Cheap flights from Tampa to San Francisco from $159

If you aren’t able to travel to San Francisco during the month of November, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $389.

The cheapest day to depart from Tampa to San Francisco is on a Friday when prices can be found for as low as $478. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $934.

Our data shows that the cheapest Tampa to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $537. Flights in the evening are often more expensive with an average ticket price of $1,120.

Fly from Tampa to San Francisco for the best Tampa - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $401 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Tampa for as low as $364 on momondo.

There are 4 cabin classes available to choose from on Tampa to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Tampa to San Francisco.

As of February 2026, prices for Tampa to San Francisco flights are approximately 58% more expensive when compared to flights at the same time last year.

Southwest, United Airlines, and Alaska Airlines are the most popular carriers operating from Tampa to San Francisco

United Airlines, Frontier and Delta are the top three most popular airlines that fly to San Francisco from Tampa according to our data. United Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 7 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Charlotte (CLT) was the most common stop: 39% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $197.

Flights connecting via Los Angeles (LAX) have the shortest average one-way travel time: 7h 21m.

Charlotte (CLT) has the shortest average layover time for this route: 0h 43m.

6 flights are operational daily from Tampa to San Francisco as of February 2026. The most popular departure time for this route is 6:00AM, with 72% of flights per day taking off at noon.

43 flights are operational weekly from Tampa to San Francisco as of February 2026. The most popular departure day for this route is Mon, with 16% of flights per week taking off on this day.