Cheap flights from Tampa to San Francisco from $166

If you aren’t able to travel to San Francisco during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $400.

The cheapest day to depart from Tampa to San Francisco is on a Wednesday when prices can be found for as low as $560. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $975.

Our data shows that the cheapest Tampa to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $648. Flights in the afternoon are often more expensive with an average ticket price of $989.

Fly from Tampa to San Francisco for the best Tampa - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $461 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Tampa for as low as $364 on momondo.

There are 4 cabin classes available to choose from on Tampa to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Delta, and Alaska Airlines are the most popular carriers operating from Tampa to San Francisco

United Airlines, Southwest and Frontier are the top three most popular airlines that fly to San Francisco from Tampa according to our data. United Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 7 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Denver (DEN) was the most common stop: 65% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $329.

Flights connecting via San Diego (SAN) have the shortest average one-way travel time: 7h 17m.

San Diego (SAN) has the shortest average layover time for this route: 0h 49m.

1 flights are operational daily from Tampa to San Francisco as of October 2026. The most popular departure time for this route is 7:00AM, with 57% of flights per day taking off at noon.

11 flights are operational weekly from Tampa to San Francisco as of October 2026. The most popular departure day for this route is Sat, with 64% of flights per week taking off on this day.