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Cheap flights from South Carolina to Los Angeles from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Los Angeles departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:30 pm - 11:25 am
CLT
-
SNA
19h 55m
1 stop
Frontier Logo
11:29 am - 4:56 pm
SNA
-
CLT
26h 27m
1 stop
$216Frontier
Fri, Apr 24 - Fri, May 1
Frontier Logo
6:30 pm - 11:25 am
CLT
-
SNA
19h 55m
1 stop
Frontier Logo
11:29 am - 5:23 pm
SNA
-
CLT
26h 54m
1 stop
$225Frontier
Fri, Apr 24 - Sun, Apr 26
Delta Logo
6:00 am - 4:12 pm
CHS
-
SNA
13h 12m
2 stops
Delta Logo
9:20 pm - 8:51 am
SNA
-
CHS
8h 31m
1 stop
$342Delta
Tue, Apr 21 - Mon, Apr 27
Delta Logo
6:00 am - 6:06 pm
CHS
-
SNA
15h 06m
2 stops
Delta Logo
9:20 pm - 12:24 pm
SNA
-
CHS
12h 04m
2 stops
$347Delta
Tue, Apr 21 - Mon, Apr 27
American Airlines Logo
4:41 pm - 10:45 pm
CHS
-
SNA
9h 04m
1 stop
American Airlines Logo
7:45 am - 6:02 pm
SNA
-
CHS
7h 17m
1 stop
$365American Airlines
Thu, Apr 23 - Tue, Apr 28
Spirit Airlines Logo
6:28 pm - 9:53 am
MYR
-
SNA
18h 25m
2 stops
Spirit Airlines Logo
2:53 pm - 9:43 am
SNA
-
MYR
15h 50m
2 stops
$376Spirit Airlines
Fri, Apr 10 - Tue, Apr 14
American Airlines Logo
4:41 pm - 10:45 pm
CHS
-
SNA
9h 04m
1 stop
American Airlines Logo
9:51 am - 11:59 pm
SNA
-
CHS
11h 08m
2 stops
$381American Airlines
Wed, Apr 29 - Wed, May 6
United Airlines Logo
10:34 am - 8:40 pm
MYR
-
SNA
13h 06m
2 stops
United Airlines Logo
6:26 pm - 9:04 am
SNA
-
MYR
11h 38m
2 stops
$393United Airlines
Sun, May 24 - Tue, Jun 2
United Airlines Logo
4:00 pm - 9:58 pm
CHS
-
SNA
8h 58m
1 stop
United Airlines Logo
9:00 am - 7:33 pm
SNA
-
CHS
7h 33m
1 stop
$397United Airlines
Thu, Apr 23 - Tue, Apr 28
Spirit Airlines Logo
6:28 pm - 9:53 am
MYR
-
SNA
18h 25m
2 stops
Spirit Airlines Logo
2:53 pm - 9:43 am
SNA
-
MYR
15h 50m
2 stops
$399Spirit Airlines
Thu, Apr 9 - Tue, Apr 14

Spirit Airlines flights from South Carolina to Santa Ana, California

Our best Spirit Airlines deals on South Carolina to Santa Ana, California flight tickets
Spirit Airlines
Apr 10
CLT1:20 pmCharlotte Douglas
23h 33m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
Apr 14
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
35h 04m
3 stops
CLT8:49 pmCharlotte Douglas
$361
Spirit Airlines
Apr 10
CLT1:20 pmCharlotte Douglas
23h 33m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
Apr 13
SNA10:48 amSanta Ana J. Wayne/Orange Cnty
32h 15m
3 stops
CLT10:03 pmCharlotte Douglas
$371
Spirit Airlines
Apr 10
MYR6:28 pmMyrtle Beach Intl
18h 25m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
Apr 14
SNA2:53 pmSanta Ana J. Wayne/Orange Cnty
15h 50m
2 stops
MYR9:43 amMyrtle Beach Intl
$376

Frontier flights from South Carolina to Santa Ana, California

Our best Frontier deals on South Carolina to Santa Ana, California flight tickets
Frontier
Apr 24
CLT6:30 pmCharlotte Douglas
19h 55m
1 stop
SNA11:25 amSanta Ana J. Wayne/Orange Cnty
May 1
SNA11:29 amSanta Ana J. Wayne/Orange Cnty
26h 27m
1 stop
CLT4:56 pmCharlotte Douglas
$216
Frontier
Apr 24
CLT6:30 pmCharlotte Douglas
19h 55m
1 stop
SNA11:25 amSanta Ana J. Wayne/Orange Cnty
Apr 26
SNA11:29 amSanta Ana J. Wayne/Orange Cnty
26h 54m
1 stop
CLT5:23 pmCharlotte Douglas
$225
Frontier
May 28
CLT11:26 amCharlotte Douglas
27h 53m
1 stop
SNA12:19 pmSanta Ana J. Wayne/Orange Cnty
May 29
SNA8:10 pmSanta Ana J. Wayne/Orange Cnty
8h 15m
1 stop
CLT7:25 amCharlotte Douglas
$235

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from South Carolina to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Fri 4/24

6:30 pm-11:25 am

1 stop19h 55m

Santa Ana J. Wayne/Orange Cnty

Fri 5/1

11:29 am-4:56 pm

1 stop26h 27m

$216

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Fri 4/24

6:30 pm-11:25 am

1 stop19h 55m

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

11:29 am-5:23 pm

1 stop26h 54m

$225

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Tue 4/21

6:00 am-4:12 pm

2 stops13h 12m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

9:20 pm-8:51 am

1 stop8h 31m

$342

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Tue 4/21

6:00 am-6:06 pm

2 stops15h 06m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

9:20 pm-12:24 pm

2 stops12h 04m

$347
Quickest round-trip

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 4/23

4:41 pm-10:45 pm

1 stop9h 04m

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

7:45 am-6:02 pm

1 stop7h 17m

$365

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 4/10

6:28 pm-9:53 am

2 stops18h 25m

Santa Ana J. Wayne/Orange Cnty

Tue 4/14

2:53 pm-9:43 am

2 stops15h 50m

$376

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Wed 4/29

4:41 pm-10:45 pm

1 stop9h 04m

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

9:51 am-11:59 pm

2 stops11h 08m

$381

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 5/24

10:34 am-8:40 pm

2 stops13h 06m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

6:26 pm-9:04 am

2 stops11h 38m

$393

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 4/23

4:00 pm-9:58 pm

1 stop8h 58m

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

9:00 am-7:33 pm

1 stop7h 33m

$397

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Thu 4/9

6:28 pm-9:53 am

2 stops18h 25m

Santa Ana J. Wayne/Orange Cnty

Tue 4/14

2:53 pm-9:43 am

2 stops15h 50m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, June is the cheapest month to fly from South Carolina to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $369. If you aren’t able to travel during the month of June, then book flights to Santa Ana, California from South Carolina during May instead. Flights to Santa Ana, California in May, while not as cheap as those in June, still average around $430.

Can stopping save me money on South Carolina to Santa Ana, California flights?

You could potentially save up to 29% on your flight if you consider stops on a South Carolina to Santa Ana, California flight.

Cheap South Carolina to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santa Ana, California

Fastest flight time

4h 50m

Direct flights

Every day

Airports in Santa Ana, California

1 airport
The fastest flight from South Carolina to Santa Ana, California takes 4h 50m
Direct flights go from South Carolina to Santa Ana, California every day.
There is 1 airport in Santa Ana, California. From South Carolina there are direct flights to Santa Ana J. Wayne/Orange Cnty (SNA).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santa Ana, California

Compare and see reviews for airlines that fly from South Carolina to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $206Free CancellationRating
7.4
9,491 reviews
Search United Airlines flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,504 reviews
Search American Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
8,341 reviews
Search Delta flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,331 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Santa Ana with flexible booking policies on momondo?

All flight searches from South Carolina to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from South Carolina.

I’m not ready to book a flight from South Carolina to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from South Carolina and alert you when they change.

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