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Cheap flights from South Carolina to Los Angeles from $68

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Los Angeles departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
12:17 pm - 12:42 pmCLT-SNA
27h 25m1 stop
Frontier Logo
1:17 pm - 11:22 amSNA-CLT
19h 05m1 stop
$130Frontier
Find Deal
Thu, Jan 8 - Sat, Jan 10
Frontier Logo
5:44 pm - 12:42 pmCLT-SNA
21h 58m1 stop
Frontier Logo
1:17 pm - 11:22 amSNA-CLT
19h 05m1 stop
$150Frontier
Find Deal
Thu, Dec 11 - Sat, Jan 10
Multiple Airlines Logo
5:44 pm - 12:42 pmCLT-SNA
21h 58m1 stop
Multiple Airlines Logo
11:39 am - 9:50 amSNA-CLT
19h 11m2 stops
$203Multiple Airlines
Find Deal
Thu, Dec 11 - Tue, Dec 16
Multiple Airlines Logo
5:49 pm - 12:42 pmCLT-SNA
21h 53m1 stop
Multiple Airlines Logo
8:19 pm - 6:27 pmSNA-CLT
19h 08m2 stops
$207Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Spirit Airlines Logo
8:55 am - 10:23 pmCLT-SNA
16h 28m2 stops
Spirit Airlines Logo
11:39 am - 2:03 pmSNA-CLT
23h 24m3 stops
$252Spirit Airlines
Find Deal
Fri, Dec 5 - Tue, Dec 9
Spirit Airlines Logo
8:06 pm - 4:51 pmCLT-SNA
23h 45m3 stops
Spirit Airlines Logo
6:45 am - 2:03 pmSNA-CLT
28h 18m3 stops
$260Spirit Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
American Airlines Logo
3:09 pm - 8:10 pmCAE-SNA
8h 01m1 stop
American Airlines Logo
2:47 pm - 12:06 amSNA-CAE
6h 19m1 stop
$309American Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 7
Delta Logo
5:34 am - 2:15 pmCAE-SNA
11h 41m2 stops
Delta Logo
7:45 am - 4:51 pmSNA-CAE
6h 06m1 stop
$314Delta
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Thu, Dec 4 - Sun, Dec 7
Delta Logo
2:54 pm - 8:08 pmAGS-SNA
8h 14m1 stop
Delta Logo
7:30 am - 11:33 pmSNA-AGS
13h 03m2 stops
$316Delta
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Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
4:10 pm - 8:10 pmAGS-SNA
7h 00m1 stop
American Airlines Logo
7:50 am - 4:59 pmSNA-AGS
6h 09m1 stop
$345American Airlines
Find Deal
Tue, Dec 16 - Tue, Jan 6

American Airlines flights from South Carolina to Santa Ana, California

Our best American Airlines deals on South Carolina to Santa Ana, California flight tickets
American Airlines
Dec 5
CAE3:09 pmColumbia Metropolitan
8h 01m
1 stop
SNA8:10 pmSanta Ana J. Wayne/Orange Cnty
Dec 7
SNA2:47 pmSanta Ana J. Wayne/Orange Cnty
6h 19m
1 stop
CAE12:06 amColumbia Metropolitan
$309
Find similar
American Airlines
Dec 16
AGS4:10 pmAugusta Bush Field
7h 00m
1 stop
SNA8:10 pmSanta Ana J. Wayne/Orange Cnty
Jan 6
SNA7:50 amSanta Ana J. Wayne/Orange Cnty
6h 09m
1 stop
AGS4:59 pmAugusta Bush Field
$345
Find similar
American Airlines
Dec 16
AGS7:15 amAugusta Bush Field
11h 08m
2 stops
SNA3:23 pmSanta Ana J. Wayne/Orange Cnty
Jan 6
SNA7:50 amSanta Ana J. Wayne/Orange Cnty
6h 09m
1 stop
AGS4:59 pmAugusta Bush Field
$350
Find similar

Alaska Airlines flights from South Carolina to Santa Ana, California

Our best Alaska Airlines deals on South Carolina to Santa Ana, California flight tickets
Alaska Airlines
Dec 4
CHS7:24 pmCharleston
24h 13m
1 stop
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
Dec 10
SNA8:05 amSanta Ana J. Wayne/Orange Cnty
31h 19m
1 stop
CHS6:24 pmCharleston
$364
Find similar
Alaska Airlines
Apr 23
CHS6:45 pmCharleston
16h 59m
1 stop
SNA8:44 amSanta Ana J. Wayne/Orange Cnty
Apr 28
SNA9:15 pmSanta Ana J. Wayne/Orange Cnty
17h 13m
1 stop
CHS5:28 pmCharleston
$436
Find similar
Alaska Airlines
Nov 18
GSP12:07 pmGreenville
13h 08m
2 stops
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
Dec 2
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
12h 19m
2 stops
GSP10:04 pmGreenville
$922
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momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 7, 2025.
Use the filters below to find and compare flights from South Carolina to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 1/8

12:17 pm-12:42 pm

1 stop27h 25m

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

1:17 pm-11:22 am

1 stop19h 05m

$130

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 12/11

5:44 pm-12:42 pm

1 stop21h 58m

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

1:17 pm-11:22 am

1 stop19h 05m

$150

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 12/11

5:44 pm-12:42 pm

1 stop21h 58m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

11:39 am-9:50 am

2 stops19h 11m

$203

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 12/4

5:49 pm-12:42 pm

1 stop21h 53m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

8:19 pm-6:27 pm

2 stops19h 08m

$207

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Fri 12/5

8:55 am-10:23 pm

2 stops16h 28m

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

11:39 am-2:03 pm

3 stops23h 24m

$252

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Tue 12/2

8:06 pm-4:51 pm

3 stops23h 45m

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

6:45 am-2:03 pm

3 stops28h 18m

$260

ColumbiaSanta Ana

CAE - SNA

CAESNA

Columbia Metropolitan

Fri 12/5

3:09 pm-8:10 pm

1 stop8h 01m

Santa Ana J. Wayne/Orange Cnty

Sun 12/7

2:47 pm-12:06 am

1 stop6h 19m

$309

ColumbiaSanta Ana

CAE - SNA

CAESNA

Columbia Metropolitan

Thu 12/4

5:34 am-2:15 pm

2 stops11h 41m

Santa Ana J. Wayne/Orange Cnty

Sun 12/7

7:45 am-4:51 pm

1 stop6h 06m

$314

AugustaSanta Ana

AGS - SNA

AGSSNA

Augusta Bush Field

Sat 2/21

2:54 pm-8:08 pm

1 stop8h 14m

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

7:30 am-11:33 pm

2 stops13h 03m

$316

AugustaSanta Ana

AGS - SNA

AGSSNA

Augusta Bush Field

Tue 12/16

4:10 pm-8:10 pm

1 stop7h 00m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

7:50 am-4:59 pm

1 stop6h 09m

$345

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, March is the cheapest month to fly from South Carolina to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $401. If you aren’t able to travel during the month of March, then book flights to Santa Ana, California from South Carolina during May instead. Flights to Santa Ana, California in May, while not as cheap as those in March, still average around $430.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from South Carolina to Santa Ana, California is on a Tuesday. Travelers who choose to depart for Santa Ana, California on a Tuesday will often find tickets for as low as $419. The most expensive day to fly to Santa Ana, California is Sunday, with ticket prices averaging around $672.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the evening is the cheapest time of day to fly from South Carolina to Santa Ana, California when you can find flight prices for as low as $325. Flying to Santa Ana, California in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $557.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $528 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from South Carolina for as low as $391 on momondo.

Can stopping save me money on South Carolina to Santa Ana, California flights?

You could potentially save up to 1% on your flight if you consider stops on a South Carolina to Santa Ana, California flight.

Cheap South Carolina to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santa Ana, California

Fastest flight time

5h 12m

Direct flights

Every day

Airports in Santa Ana, California

1 airport
The fastest flight from South Carolina to Santa Ana, California takes 5h 12m
Direct flights go from South Carolina to Santa Ana, California every day.
There is 1 airport near Santa Ana, California: Santa Ana J. Wayne/Orange Cnty (SNA)
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  • When did momondo last update prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santa Ana, California

Compare and see reviews for airlines that fly from South Carolina to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $270Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $300Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Santa Ana with flexible booking policies on momondo?

All flight searches from South Carolina to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from South Carolina.

I’m not ready to book a flight from South Carolina to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from South Carolina and alert you when they change.

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