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Cheap flights from South Carolina to Los Angeles from $88

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Los Angeles departing on 4/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:49 pm - 10:46 am
CLT
-
SNA
17h 57m
1 stop
Frontier Logo
11:32 am - 6:54 pm
SNA
-
CLT
28h 22m
1 stop
$211Frontier
Thu, Apr 16 - Mon, Apr 20
Frontier Logo
7:49 pm - 10:46 am
CLT
-
SNA
17h 57m
1 stop
Frontier Logo
11:32 am - 6:54 pm
SNA
-
CLT
28h 22m
1 stop
$232Frontier
Thu, Apr 16 - Mon, Apr 20
Multiple Airlines Logo
7:49 pm - 10:46 am
CLT
-
SNA
17h 57m
1 stop
Multiple Airlines Logo
4:37 pm - 9:19 am
SNA
-
CLT
13h 42m
2 stops
$239Multiple Airlines
Thu, Apr 16 - Thu, Apr 23
Spirit Airlines Logo
10:14 am - 8:57 pm
CLT
-
SNA
13h 43m
2 stops
Spirit Airlines Logo
4:37 pm - 8:26 am
SNA
-
CLT
12h 49m
2 stops
$248Spirit Airlines
Mon, Apr 27 - Sat, May 2
Spirit Airlines Logo
1:20 pm - 9:53 am
CLT
-
SNA
23h 33m
2 stops
Spirit Airlines Logo
4:37 pm - 8:26 am
SNA
-
CLT
12h 49m
2 stops
$249Spirit Airlines
Fri, Apr 10 - Sat, Apr 18
Multiple Airlines Logo
7:49 pm - 10:46 am
CLT
-
SNA
17h 57m
1 stop
Multiple Airlines Logo
4:37 pm - 9:19 am
SNA
-
CLT
13h 42m
2 stops
$260Multiple Airlines
Thu, Apr 16 - Thu, Apr 23
Delta Logo
4:01 pm - 7:47 pm
CAE
-
SNA
6h 46m
1 stop
Delta Logo
9:20 pm - 9:15 am
SNA
-
CAE
8h 55m
1 stop
$329Delta
Tue, May 5 - Mon, May 11
Delta Logo
5:40 am - 10:55 am
CAE
-
SNA
8h 15m
1 stop
Delta Logo
5:11 pm - 9:15 am
SNA
-
CAE
13h 04m
2 stops
$334Delta
Thu, May 7 - Tue, May 12
United Airlines Logo
4:55 pm - 10:26 pm
CHS
-
SNA
8h 31m
1 stop
United Airlines Logo
8:49 am - 9:10 pm
SNA
-
CHS
9h 21m
1 stop
$337United Airlines
Mon, Mar 9 - Wed, Mar 11
United Airlines Logo
4:00 pm - 10:15 pm
CHS
-
SNA
9h 15m
1 stop
United Airlines Logo
6:34 pm - 9:15 am
SNA
-
CHS
11h 41m
2 stops
$392United Airlines
Thu, Mar 12 - Mon, Mar 16

Frontier flights from South Carolina to Santa Ana

Our best Frontier deals on South Carolina to Santa Ana flight tickets
Frontier
Apr 16
CLT7:49 pmCharlotte Douglas
17h 57m
1 stop
SNA10:46 amSanta Ana J. Wayne/Orange Cnty
Apr 20
SNA11:32 amSanta Ana J. Wayne/Orange Cnty
28h 22m
1 stop
CLT6:54 pmCharlotte Douglas
$211
Frontier
Feb 27
CLT5:13 pmCharlotte Douglas
21h 27m
1 stop
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
Mar 1
SNA11:22 amSanta Ana J. Wayne/Orange Cnty
25h 56m
1 stop
CLT4:18 pmCharlotte Douglas
$286
Frontier
Apr 16
CLT7:49 pmCharlotte Douglas
17h 57m
1 stop
SNA10:46 amSanta Ana J. Wayne/Orange Cnty
Apr 23
SNA11:32 amSanta Ana J. Wayne/Orange Cnty
28h 22m
1 stop
CLT6:54 pmCharlotte Douglas
$291

Southwest flights from South Carolina to Santa Ana

Our best Southwest deals on South Carolina to Santa Ana flight tickets
Southwest
Feb 28
CLT5:25 amCharlotte Douglas
14h 20m
1 stop
SNA4:45 pmSanta Ana J. Wayne/Orange Cnty
Mar 3
SNA7:25 amSanta Ana J. Wayne/Orange Cnty
8h 05m
1 stop
CLT6:30 pmCharlotte Douglas
$336
Southwest
Feb 28
CLT5:25 amCharlotte Douglas
14h 20m
1 stop
SNA4:45 pmSanta Ana J. Wayne/Orange Cnty
Mar 3
SNA6:40 pmSanta Ana J. Wayne/Orange Cnty
15h 00m
2 stops
CLT12:40 pmCharlotte Douglas
$347
Southwest
Mar 3
CLT1:35 pmCharlotte Douglas
10h 25m
2 stops
SNA9:00 pmSanta Ana J. Wayne/Orange Cnty
Mar 7
SNA7:20 pmSanta Ana J. Wayne/Orange Cnty
10h 40m
2 stops
CLT9:00 amCharlotte Douglas
$362

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from South Carolina to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 4/16

7:49 pm-10:46 am

1 stop17h 57m

Santa Ana J. Wayne/Orange Cnty

Mon 4/20

11:32 am-6:54 pm

1 stop28h 22m

$211

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 4/16

7:49 pm-10:46 am

1 stop17h 57m

Santa Ana J. Wayne/Orange Cnty

Mon 4/20

11:32 am-6:54 pm

1 stop28h 22m

$232

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 4/16

7:49 pm-10:46 am

1 stop17h 57m

Santa Ana J. Wayne/Orange Cnty

Thu 4/23

4:37 pm-9:19 am

2 stops13h 42m

$239

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Mon 4/27

10:14 am-8:57 pm

2 stops13h 43m

Santa Ana J. Wayne/Orange Cnty

Sat 5/2

4:37 pm-8:26 am

2 stops12h 49m

$248

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Fri 4/10

1:20 pm-9:53 am

2 stops23h 33m

Santa Ana J. Wayne/Orange Cnty

Sat 4/18

4:37 pm-8:26 am

2 stops12h 49m

$249

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 4/16

7:49 pm-10:46 am

1 stop17h 57m

Santa Ana J. Wayne/Orange Cnty

Thu 4/23

4:37 pm-9:19 am

2 stops13h 42m

$260

ColumbiaSanta Ana

CAE - SNA

CAESNA

Columbia Metropolitan

Tue 5/5

4:01 pm-7:47 pm

1 stop6h 46m

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

9:20 pm-9:15 am

1 stop8h 55m

$329

ColumbiaSanta Ana

CAE - SNA

CAESNA

Columbia Metropolitan

Thu 5/7

5:40 am-10:55 am

1 stop8h 15m

Santa Ana J. Wayne/Orange Cnty

Tue 5/12

5:11 pm-9:15 am

2 stops13h 04m

$334

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Mon 3/9

4:55 pm-10:26 pm

1 stop8h 31m

Santa Ana J. Wayne/Orange Cnty

Wed 3/11

8:49 am-9:10 pm

1 stop9h 21m

$337

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 3/12

4:00 pm-10:15 pm

1 stop9h 15m

Santa Ana J. Wayne/Orange Cnty

Mon 3/16

6:34 pm-9:15 am

2 stops11h 41m

$392

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from South Carolina is in March. Flight prices, which tend to average around $403, are often lower during this time because this is during the off-season. The month of June is another great option to travel to Santa Ana, with average flight prices from South Carolina averaging around $413.

Can stopping save me money on South Carolina to Santa Ana flights?

You could potentially save up to 44% on your flight if you consider stops on a South Carolina to Santa Ana flight.

Cheap South Carolina to Santa Ana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santa Ana

Fastest flight time

5h 14m

Direct flights

Every day

Airports in Santa Ana

1 airport
The fastest flight from South Carolina to Santa Ana takes 5h 14m
Direct flights go from South Carolina to Santa Ana every day.
There is 1 airport in Santa Ana. From South Carolina there are direct flights to Santa Ana J. Wayne/Orange Cnty (SNA).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santa Ana

Compare and see reviews for airlines that fly from South Carolina to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $270Free CancellationRating
7.4
9,249 reviews
Search United Airlines flights
American AirlinesPriceFrom $278Free CancellationRating
7.2
11,248 reviews
Search American Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
8,169 reviews
Search Delta flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,280 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Santa Ana with flexible booking policies on momondo?

All flight searches from South Carolina to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from South Carolina.

I’m not ready to book a flight from South Carolina to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from South Carolina and alert you when they change.

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