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Cheap flights from South Carolina to Los Angeles from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Los Angeles departing on 6/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
10:14 pm - 9:29 am
CLT
-
SNA
14h 15m
1 stop
Frontier Logo
6:39 pm - 11:16 am
SNA
-
CLT
13h 37m
1 stop
$244Frontier
Sat, Jun 27 - Mon, Jul 13
Frontier Logo
12:06 pm - 5:54 pm
CLT
-
SNA
8h 48m
1 stop
Frontier Logo
6:39 pm - 11:16 am
SNA
-
CLT
13h 37m
1 stop
$250Frontier
Thu, Jul 30 - Fri, Aug 7
Breeze Airways Logo
6:45 am - 11:56 am
CHS
-
SNA
8h 11m
1 stop
Breeze Airways Logo
1:00 pm - 9:38 am
SNA
-
CHS
17h 38m
1 stop
$375Breeze Airways
Thu, May 28 - Tue, Jun 2
Breeze Airways Logo
6:45 am - 11:56 am
CHS
-
SNA
8h 11m
1 stop
Breeze Airways Logo
1:00 pm - 8:43 am
SNA
-
CHS
16h 43m
2 stops
$379Breeze Airways
Thu, May 28 - Tue, Jun 2
Multiple Airlines Logo
6:45 am - 11:56 am
CHS
-
SNA
8h 11m
1 stop
Multiple Airlines Logo
10:55 am - 8:38 am
SNA
-
CHS
18h 43m
2 stops
$388Multiple Airlines
Thu, May 28 - Wed, Jun 3
Delta Logo
6:15 am - 12:40 pm
CHS
-
SNA
9h 25m
1 stop
Delta Logo
2:00 pm - 11:59 pm
SNA
-
CHS
6h 59m
1 stop
$391Delta
Tue, Jun 2 - Wed, Jun 3
American Airlines Logo
3:44 pm - 8:26 pm
CHS
-
SNA
7h 42m
1 stop
American Airlines Logo
1:01 pm - 10:57 pm
SNA
-
CHS
6h 56m
1 stop
$392American Airlines
Tue, Jun 9 - Tue, Jun 16
Delta Logo
5:16 pm - 10:25 pm
GSP
-
SNA
8h 09m
1 stop
Delta Logo
12:15 pm - 10:55 pm
SNA
-
GSP
7h 40m
1 stop
$395Delta
Tue, Jul 21 - Tue, Jul 28
American Airlines Logo
5:27 pm - 10:25 pm
GSP
-
SNA
7h 58m
1 stop
American Airlines Logo
11:55 am - 11:17 pm
SNA
-
GSP
8h 22m
1 stop
$396American Airlines
Tue, Jul 21 - Tue, Jul 28
Multiple Airlines Logo
8:50 pm - 12:43 pm
CHS
-
SNA
18h 53m
1 stop
Multiple Airlines Logo
1:00 pm - 9:38 am
SNA
-
CHS
17h 38m
1 stop
$399Multiple Airlines
Sat, May 30 - Tue, Jun 2

American Airlines flights from South Carolina to Santa Ana, California

Our best American Airlines deals on South Carolina to Santa Ana, California flight tickets
American Airlines
Jun 9
CHS3:44 pmCharleston
7h 42m
1 stop
SNA8:26 pmSanta Ana J. Wayne/Orange Cnty
Jun 16
SNA1:01 pmSanta Ana J. Wayne/Orange Cnty
6h 56m
1 stop
CHS10:57 pmCharleston
$392
American Airlines
Jul 21
GSP5:27 pmGreenville
7h 58m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
Jul 28
SNA11:55 amSanta Ana J. Wayne/Orange Cnty
8h 22m
1 stop
GSP11:17 pmGreenville
$396
American Airlines
Jul 21
GSP5:27 pmGreenville
7h 58m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
Jul 28
SNA11:55 amSanta Ana J. Wayne/Orange Cnty
8h 56m
2 stops
GSP11:51 pmGreenville
$400

Frontier flights from South Carolina to Santa Ana, California

Our best Frontier deals on South Carolina to Santa Ana, California flight tickets
Frontier
Jun 27
CLT10:14 pmCharlotte Douglas
14h 15m
1 stop
SNA9:29 amSanta Ana J. Wayne/Orange Cnty
Jul 13
SNA6:39 pmSanta Ana J. Wayne/Orange Cnty
13h 37m
1 stop
CLT11:16 amCharlotte Douglas
$244
Frontier
Jul 30
CLT12:06 pmCharlotte Douglas
8h 48m
1 stop
SNA5:54 pmSanta Ana J. Wayne/Orange Cnty
Aug 7
SNA6:39 pmSanta Ana J. Wayne/Orange Cnty
13h 37m
1 stop
CLT11:16 amCharlotte Douglas
$250
Frontier
Jul 26
CLT12:06 pmCharlotte Douglas
8h 48m
1 stop
SNA5:54 pmSanta Ana J. Wayne/Orange Cnty
Jul 27
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
9h 28m
1 stop
CLT9:23 pmCharlotte Douglas
$270

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from South Carolina to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Sat 6/27

10:14 pm-9:29 am

1 stop14h 15m

Santa Ana J. Wayne/Orange Cnty

Mon 7/13

6:39 pm-11:16 am

1 stop13h 37m

$244

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Thu 7/30

12:06 pm-5:54 pm

1 stop8h 48m

Santa Ana J. Wayne/Orange Cnty

Fri 8/7

6:39 pm-11:16 am

1 stop13h 37m

$250

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 5/28

6:45 am-11:56 am

1 stop8h 11m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

1:00 pm-9:38 am

1 stop17h 38m

$375

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 5/28

6:45 am-11:56 am

1 stop8h 11m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

1:00 pm-8:43 am

2 stops16h 43m

$379

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 5/28

6:45 am-11:56 am

1 stop8h 11m

Santa Ana J. Wayne/Orange Cnty

Wed 6/3

10:55 am-8:38 am

2 stops18h 43m

$388

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Tue 6/2

6:15 am-12:40 pm

1 stop9h 25m

Santa Ana J. Wayne/Orange Cnty

Wed 6/3

2:00 pm-11:59 pm

1 stop6h 59m

$391
Quickest round-trip

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Tue 6/9

3:44 pm-8:26 pm

1 stop7h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 6/16

1:01 pm-10:57 pm

1 stop6h 56m

$392

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 7/21

5:16 pm-10:25 pm

1 stop8h 09m

Santa Ana J. Wayne/Orange Cnty

Tue 7/28

12:15 pm-10:55 pm

1 stop7h 40m

$395

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 7/21

5:27 pm-10:25 pm

1 stop7h 58m

Santa Ana J. Wayne/Orange Cnty

Tue 7/28

11:55 am-11:17 pm

1 stop8h 22m

$396

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Sat 5/30

8:50 pm-12:43 pm

1 stop18h 53m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

1:00 pm-9:38 am

1 stop17h 38m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from South Carolina to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, February is the cheapest month to fly from South Carolina to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $178. If you aren’t able to travel during the month of February, then book flights to Santa Ana, California from South Carolina during June instead. Flights to Santa Ana, California in June, while not as cheap as those in February, still average around $194.

Can stopping save me money on South Carolina to Santa Ana, California flights?

You could potentially save up to 25% on your flight if you consider stops on a South Carolina to Santa Ana, California flight.

Cheap South Carolina to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santa Ana, California

Fastest flight time

4h 59m

Direct flights

Every day

Airports in Santa Ana, California

1 airport
The fastest flight from South Carolina to Santa Ana, California takes 4h 59m
Direct flights go from South Carolina to Santa Ana, California every day.
There is 1 airport in Santa Ana, California. From South Carolina there are direct flights to Santa Ana J. Wayne/Orange Cnty (SNA).
Search flight deals

Frequently asked questions about flying from South Carolina to Santa Ana, California

  • When did momondo last update prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santa Ana, California

Compare and see reviews for airlines that fly from South Carolina to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $206Free CancellationRating
7.4
9,712 reviews
Search United Airlines flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
8,455 reviews
Search Delta flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Santa Ana with flexible booking policies on momondo?

All flight searches from South Carolina to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from South Carolina.

I’m not ready to book a flight from South Carolina to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from South Carolina and alert you when they change.

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