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Cheap flights from South Carolina to Los Angeles from $88

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Los Angeles departing on 8/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:46 pm - 10:12 amCLT  Charlotte Douglas-SNA Santa Ana J. Wayne/Orange Cnty
17h 26m1 stop Denver Intl
Frontier Logo
7:28 pm - 11:15 amSNA  Santa Ana J. Wayne/Orange Cnty-CLT Charlotte Douglas
12h 47m1 stop Dallas/Fort Worth
$198Frontier
Fri, Oct 23 - Fri, Oct 30
Frontier Logo
7:44 pm - 10:11 amCLT  Charlotte Douglas-SNA Santa Ana J. Wayne/Orange Cnty
17h 27m1 stop Denver Intl
Frontier Logo
7:28 pm - 11:15 amSNA  Santa Ana J. Wayne/Orange Cnty-CLT Charlotte Douglas
12h 47m1 stop Dallas/Fort Worth
$208Frontier
Fri, Oct 30 - Mon, Nov 2
American Airlines Logo
3:41 pm - 10:29 pmCHS  Charleston-SNA Santa Ana J. Wayne/Orange Cnty
9h 48m1 stop Dallas/Fort Worth
American Airlines Logo
10:42 am - 10:26 pmSNA  Santa Ana J. Wayne/Orange Cnty-CHS Charleston
8h 44m1 stop Dallas/Fort Worth
$267American Airlines
Tue, Oct 20 - Sat, Oct 24
Southwest Logo
2:10 pm - 9:05 pmCHS  Charleston-SNA Santa Ana J. Wayne/Orange Cnty
9h 55m1 stop Denver Intl
Southwest Logo
6:45 am - 7:30 pmSNA  Santa Ana J. Wayne/Orange Cnty-CHS Charleston
9h 45m2 stops Dallas Love Field Nashville Intl
$273Southwest
Sat, Oct 24 - Tue, Oct 27
American Airlines Logo
7:00 am - 1:45 pmCHS  Charleston-SNA Santa Ana J. Wayne/Orange Cnty
9h 45m1 stop Dallas/Fort Worth
American Airlines Logo
7:15 am - 4:44 pmSNA  Santa Ana J. Wayne/Orange Cnty-CHS Charleston
6h 29m1 stop Charlotte Douglas
$297American Airlines
Sat, Oct 24 - Tue, Oct 27
United Airlines Logo
5:45 am - 2:02 pmCHS  Charleston-SNA Santa Ana J. Wayne/Orange Cnty
11h 17m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
United Airlines Logo
12:06 pm - 10:21 pmSNA  Santa Ana J. Wayne/Orange Cnty-CHS Charleston
7h 15m1 stop Houston George Bush Intcntl
$302United Airlines
Tue, Sep 22 - Tue, Sep 29
United Airlines Logo
4:13 pm - 10:02 pmCHS  Charleston-SNA Santa Ana J. Wayne/Orange Cnty
8h 49m1 stop Denver Intl
United Airlines Logo
9:00 pm - 9:14 amSNA  Santa Ana J. Wayne/Orange Cnty-CHS Charleston
9h 14m1 stop Newark
$304United Airlines
Thu, Sep 24 - Sat, Sep 26
Southwest Logo
6:50 am - 12:30 pmCLT  Charlotte Douglas-SNA Santa Ana J. Wayne/Orange Cnty
8h 40m2 stops Nashville Intl Dallas Love Field
Southwest Logo
7:10 am - 5:35 pmSNA  Santa Ana J. Wayne/Orange Cnty-CLT Charlotte Douglas
7h 25m1 stop Dallas Love Field
$306Southwest
Tue, Jan 26 - Sat, Jan 30
Delta Logo
5:43 pm - 10:14 pmCHS  Charleston-SNA Santa Ana J. Wayne/Orange Cnty
7h 31m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:15 pm - 9:36 amSNA  Santa Ana J. Wayne/Orange Cnty-CHS Charleston
9h 21m1 stop Atlanta Hartsfield-Jackson
$339Delta
Fri, Dec 4 - Fri, Dec 11
Delta Logo
4:40 pm - 10:04 pmSAV  Savannah/Hilton Head-SNA Santa Ana J. Wayne/Orange Cnty
8h 24m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 11:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-SAV Savannah/Hilton Head
6h 55m1 stop Atlanta Hartsfield-Jackson
$348Delta
Tue, Sep 15 - Fri, Sep 18

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American Airlines flights from South Carolina to Santa Ana, California

Our best American Airlines deals on South Carolina to Santa Ana, California flight tickets
American Airlines
Oct 20
CHS3:41 pmCharleston
9h 48m
1 stop
SNA10:29 pmSanta Ana J. Wayne/Orange Cnty
Oct 24
SNA10:42 amSanta Ana J. Wayne/Orange Cnty
8h 44m
1 stop
CHS10:26 pmCharleston
$267
American Airlines
Sep 22
CHS6:44 amCharleston
7h 06m
1 stop
SNA10:50 amSanta Ana J. Wayne/Orange Cnty
Sep 29
SNA12:14 pmSanta Ana J. Wayne/Orange Cnty
7h 34m
1 stop
CHS10:48 pmCharleston
$297
American Airlines
Dec 3
SAV2:45 pmSavannah/Hilton Head
7h 25m
1 stop
SNA7:10 pmSanta Ana J. Wayne/Orange Cnty
Dec 7
SNA7:15 amSanta Ana J. Wayne/Orange Cnty
6h 53m
1 stop
SAV5:08 pmSavannah/Hilton Head
$305

Delta flights from South Carolina to Santa Ana, California

Our best Delta deals on South Carolina to Santa Ana, California flight tickets
Delta
Oct 19
CLT5:44 pmCharlotte Douglas
7h 21m
1 stop
SNA10:05 pmSanta Ana J. Wayne/Orange Cnty
Oct 25
SNA9:30 pmSanta Ana J. Wayne/Orange Cnty
9h 26m
1 stop
CLT9:56 amCharlotte Douglas
$267
Delta
Aug 28
CLT2:51 pmCharlotte Douglas
8h 16m
1 stop
SNA8:07 pmSanta Ana J. Wayne/Orange Cnty
Sep 1
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 57m
1 stop
CLT11:57 pmCharlotte Douglas
$277
Delta
Sep 30
CLT5:50 pmCharlotte Douglas
7h 14m
1 stop
SNA10:04 pmSanta Ana J. Wayne/Orange Cnty
Oct 3
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 59m
1 stop
CLT11:59 pmCharlotte Douglas
$287

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from South Carolina to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSanta Ana

CLT Charlotte Douglas - SNA Santa Ana J. Wayne/Orange Cnty

CLTSNA

Charlotte Douglas

Fri 10/23

7:46 pm-10:12 am

1 stop17h 26m

Santa Ana J. Wayne/Orange Cnty

Fri 10/30

7:28 pm-11:15 am

1 stop12h 47m

$198

CharlotteSanta Ana

CLT Charlotte Douglas - SNA Santa Ana J. Wayne/Orange Cnty

CLTSNA

Charlotte Douglas

Fri 10/30

7:44 pm-10:11 am

1 stop17h 27m

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

7:28 pm-11:15 am

1 stop12h 47m

$208

CharlestonSanta Ana

CHS Charleston - SNA Santa Ana J. Wayne/Orange Cnty

CHSSNA

Charleston

Tue 10/20

3:41 pm-10:29 pm

1 stop9h 48m

Santa Ana J. Wayne/Orange Cnty

Sat 10/24

10:42 am-10:26 pm

1 stop8h 44m

$267

CharlestonSanta Ana

CHS Charleston - SNA Santa Ana J. Wayne/Orange Cnty

CHSSNA

Charleston

Sat 10/24

2:10 pm-9:05 pm

1 stop9h 55m

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

6:45 am-7:30 pm

2 stops9h 45m

$273

CharlestonSanta Ana

CHS Charleston - SNA Santa Ana J. Wayne/Orange Cnty

CHSSNA

Charleston

Sat 10/24

7:00 am-1:45 pm

1 stop9h 45m

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

7:15 am-4:44 pm

1 stop6h 29m

$297

CharlestonSanta Ana

CHS Charleston - SNA Santa Ana J. Wayne/Orange Cnty

CHSSNA

Charleston

Tue 9/22

5:45 am-2:02 pm

2 stops11h 17m

Santa Ana J. Wayne/Orange Cnty

Tue 9/29

12:06 pm-10:21 pm

1 stop7h 15m

$302

CharlestonSanta Ana

CHS Charleston - SNA Santa Ana J. Wayne/Orange Cnty

CHSSNA

Charleston

Thu 9/24

4:13 pm-10:02 pm

1 stop8h 49m

Santa Ana J. Wayne/Orange Cnty

Sat 9/26

9:00 pm-9:14 am

1 stop9h 14m

$304

CharlotteSanta Ana

CLT Charlotte Douglas - SNA Santa Ana J. Wayne/Orange Cnty

CLTSNA

Charlotte Douglas

Tue 1/26

6:50 am-12:30 pm

2 stops8h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 1/30

7:10 am-5:35 pm

1 stop7h 25m

$306

CharlestonSanta Ana

CHS Charleston - SNA Santa Ana J. Wayne/Orange Cnty

CHSSNA

Charleston

Fri 12/4

5:43 pm-10:14 pm

1 stop7h 31m

Santa Ana J. Wayne/Orange Cnty

Fri 12/11

9:15 pm-9:36 am

1 stop9h 21m

$339
Quickest round-trip

SavannahSanta Ana

SAV Savannah/Hilton Head - SNA Santa Ana J. Wayne/Orange Cnty

SAVSNA

Savannah/Hilton Head

Tue 9/15

4:40 pm-10:04 pm

1 stop8h 24m

Santa Ana J. Wayne/Orange Cnty

Fri 9/18

2:00 pm-11:55 pm

1 stop6h 55m

$348

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from South Carolina to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, September is the cheapest month to fly from South Carolina to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $446. If you aren’t able to travel during the month of September, then book flights to Santa Ana, California from South Carolina during February instead. Flights to Santa Ana, California in February, while not as cheap as those in September, still average around $475.

Can stopping save me money on South Carolina to Santa Ana, California flights?

You could potentially save up to 12% on your flight if you consider stops on a South Carolina to Santa Ana, California flight.

Cheap South Carolina to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santa Ana, California

Fastest flight time

4h 59m

Direct flights

Every day

Airports in Santa Ana, California

1 airport
The fastest flight from South Carolina to Santa Ana, California takes 4h 59m
Direct flights go from South Carolina to Santa Ana, California every day.
There is 1 airport in Santa Ana, California. From South Carolina there are direct flights to Santa Ana J. Wayne/Orange Cnty (SNA).
Search flight deals

Frequently asked questions about flying from South Carolina to Santa Ana, California

  • When did momondo last update prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santa Ana, California

Compare and see reviews for airlines that fly from South Carolina to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $178Free CancellationRating
7.8
8,508 reviews
Search Delta flights
United AirlinesPriceFrom $206Free CancellationRating
7.4
10,111 reviews
Search United Airlines flights
American AirlinesPriceFrom $306Free CancellationRating
7.1
11,941 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,219 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Santa Ana with flexible booking policies on momondo?

All flight searches from South Carolina to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from South Carolina.

I’m not ready to book a flight from South Carolina to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from South Carolina and alert you when they change.

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