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Cheap flights from South Carolina to San Diego from $65

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to San Diego departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
10:10 am - 7:50 pmCHS-SAN
12h 40m1 stop
JetBlue Logo
9:00 pm - 9:20 amSAN-CHS
9h 20m1 stop
$275JetBlue
Find Deal
jue., ene. 8 - dom., ene. 11
JetBlue Logo
12:59 pm - 7:11 pmSAV-SAN
9h 12m1 stop
JetBlue Logo
8:31 pm - 10:55 amSAN-SAV
11h 24m1 stop
$297JetBlue
Find Deal
jue., dic. 4 - jue., dic. 11
Alaska Airlines Logo
7:24 pm - 10:13 amCHS-SAN
17h 49m1 stop
Alaska Airlines Logo
4:25 pm - 6:24 pmSAN-CHS
22h 59m1 stop
$306Alaska Airlines
Find Deal
mié., dic. 3 - mié., dic. 10
Delta Logo
6:00 am - 12:17 pmCHS-SAN
9h 17m1 stop
Delta Logo
6:15 am - 5:40 pmSAN-CHS
8h 25m1 stop
$307Delta
Find Deal
mar., mar. 3 - mié., mar. 4
Delta Logo
12:45 pm - 7:41 pmCAE-SAN
9h 56m1 stop
Delta Logo
8:00 am - 7:27 pmSAN-CAE
8h 27m1 stop
$309Delta
Find Deal
vie., ene. 9 - mar., ene. 13
United Airlines Logo
4:11 pm - 10:30 pmCHS-SAN
9h 19m1 stop
United Airlines Logo
8:40 pm - 10:46 amSAN-CHS
11h 06m2 stops
$312United Airlines
Find Deal
mié., dic. 3 - mié., dic. 10
United Airlines Logo
2:29 pm - 10:20 pmCAE-SAN
10h 51m1 stop
United Airlines Logo
10:34 pm - 2:15 pmSAN-CAE
12h 41m2 stops
$314United Airlines
Find Deal
lun., nov. 24 - mar., dic. 2
Alaska Airlines Logo
6:45 pm - 12:07 amCHS-SAN
32h 22m1 stop
Alaska Airlines Logo
7:00 am - 5:31 pmSAN-CHS
31h 31m1 stop
$324Alaska Airlines
Find Deal
mié., feb. 18 - lun., feb. 23
American Airlines Logo
11:42 am - 8:45 pmGSP-SAN
12h 03m1 stop
American Airlines Logo
6:15 am - 7:44 pmSAN-GSP
10h 29m1 stop
$338American Airlines
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mar., dic. 9 - dom., dic. 14
American Airlines Logo
6:00 am - 12:41 pmGSP-SAN
9h 41m1 stop
American Airlines Logo
6:15 am - 9:45 pmSAN-GSP
12h 30m1 stop
$344American Airlines
Find Deal
mié., dic. 3 - mié., dic. 10

Alaska Airlines flights from South Carolina to San Diego

Our best Alaska Airlines deals on South Carolina to San Diego flight tickets
Alaska Airlines
Dec 3
CHS7:24 pmCharleston
17h 49m
1 stop
SAN10:13 amSan Diego
Dec 10
SAN4:25 pmSan Diego
22h 59m
1 stop
CHS6:24 pmCharleston
$306
Find similar
Alaska Airlines
Feb 18
CHS6:45 pmCharleston
32h 22m
1 stop
SAN12:07 amSan Diego
Feb 23
SAN7:00 amSan Diego
31h 31m
1 stop
CHS5:31 pmCharleston
$324
Find similar
Alaska Airlines
Mar 3
CHS6:45 pmCharleston
32h 22m
1 stop
SAN12:07 amSan Diego
Mar 6
SAN8:50 pmSan Diego
17h 41m
1 stop
CHS5:31 pmCharleston
$354
Find similar

Delta flights from South Carolina to San Diego

Our best Delta deals on South Carolina to San Diego flight tickets
Delta
Mar 3
CHS6:00 amCharleston
9h 17m
1 stop
SAN12:17 pmSan Diego
Mar 4
SAN6:15 amSan Diego
8h 25m
1 stop
CHS5:40 pmCharleston
$307
Find similar
Delta
Jan 9
CAE12:45 pmColumbia Metropolitan
9h 56m
1 stop
SAN7:41 pmSan Diego
Jan 13
SAN8:00 amSan Diego
8h 27m
1 stop
CAE7:27 pmColumbia Metropolitan
$309
Find similar
Delta
Dec 3
SAV7:00 amSavannah/Hilton Head
19h 58m
1 stop
SAN11:58 pmSan Diego
Dec 9
SAN10:15 pmSan Diego
20h 20m
1 stop
SAV9:35 pmSavannah/Hilton Head
$323
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

jue. 1/8

10:10 am-7:50 pm

1 stop12h 40m

San Diego

dom. 1/11

9:00 pm-9:20 am

1 stop9h 20m

$275

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

jue. 12/4

12:59 pm-7:11 pm

1 stop9h 12m

San Diego

jue. 12/11

8:31 pm-10:55 am

1 stop11h 24m

$297

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

mié. 12/3

7:24 pm-10:13 am

1 stop17h 49m

San Diego

mié. 12/10

4:25 pm-6:24 pm

1 stop22h 59m

$306

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

mar. 3/3

6:00 am-12:17 pm

1 stop9h 17m

San Diego

mié. 3/4

6:15 am-5:40 pm

1 stop8h 25m

$307

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

vie. 1/9

12:45 pm-7:41 pm

1 stop9h 56m

San Diego

mar. 1/13

8:00 am-7:27 pm

1 stop8h 27m

$309

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

mié. 12/3

4:11 pm-10:30 pm

1 stop9h 19m

San Diego

mié. 12/10

8:40 pm-10:46 am

2 stops11h 06m

$312

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

lun. 11/24

2:29 pm-10:20 pm

1 stop10h 51m

San Diego

mar. 12/2

10:34 pm-2:15 pm

2 stops12h 41m

$314

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

mié. 2/18

6:45 pm-12:07 am

1 stop32h 22m

San Diego

lun. 2/23

7:00 am-5:31 pm

1 stop31h 31m

$324

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

mar. 12/9

11:42 am-8:45 pm

1 stop12h 03m

San Diego

dom. 12/14

6:15 am-7:44 pm

1 stop10h 29m

$338

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

mié. 12/3

6:00 am-12:41 pm

1 stop9h 41m

San Diego

mié. 12/10

6:15 am-9:45 pm

1 stop12h 30m

$344

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from South Carolina to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from South Carolina during the month September is also very affordable. Most momondo users find prices during this month for around $344.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from South Carolina to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $437. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $545. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $444. Flights in the morning are often more expensive with an average ticket price of $491.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $407 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from South Carolina for as low as $291 on momondo.

Can stopping save me money on South Carolina to San Diego flights?

You could potentially save up to 8% on your flight if you consider stops on a South Carolina to San Diego flight.

Cheap South Carolina to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to San Diego

Fastest flight time

5h 10m

Direct flights

Every day

Airports in San Diego

1 airport
The fastest flight from South Carolina to San Diego takes 5h 10m
Direct flights go from South Carolina to San Diego every day.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • When did momondo last update prices for flights from South Carolina to San Diego Airport?

    Prices for flights from South Carolina to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to San Diego Airport?

  • How old do you have to be to fly from South Carolina to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to San Diego

Compare and see reviews for airlines that fly from South Carolina to San Diego with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $170Free CancellationRating
7.2
2,907 reviews
Search JetBlue flights
DeltaPriceFrom $257Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $294Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
SouthwestPriceFrom $348Free CancellationRating
8.0
4,240 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from South Carolina.

Can I find flights from South Carolina to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to San Diego?

Once all potential South Carolina to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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