Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to San Diego from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to San Diego departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to San Diego

Cheap round-trip flights

JetBlue Logo
12:05 pm - 7:34 pmCHS-SAN
10h 29m1 stop
JetBlue Logo
8:55 pm - 11:19 amSAN-CHS
11h 24m1 stop
$275JetBlue
Find Deal
Tue, Feb 24 - Tue, Mar 10
JetBlue Logo
12:16 pm - 8:08 pmSAV-SAN
10h 52m1 stop
JetBlue Logo
9:22 pm - 11:31 amSAN-SAV
11h 09m1 stop
$297JetBlue
Find Deal
Thu, Mar 5 - Mon, Mar 9
United Airlines Logo
3:42 pm - 10:14 pmCAE-SAN
9h 32m1 stop
United Airlines Logo
10:00 pm - 10:59 amSAN-CAE
9h 59m1 stop
$309United Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
United Airlines Logo
2:53 pm - 10:14 pmCAE-SAN
10h 21m2 stops
United Airlines Logo
10:00 pm - 10:59 amSAN-CAE
9h 59m1 stop
$314United Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
Delta Logo
5:59 pm - 11:14 pmAGS-SAN
8h 15m1 stop
Delta Logo
9:48 pm - 9:05 amSAN-AGS
8h 17m1 stop
$317Delta
Find Deal
Tue, Oct 21 - Mon, Oct 27
American Airlines Logo
12:09 pm - 7:29 pmSAV-SAN
10h 20m1 stop
American Airlines Logo
9:27 pm - 9:53 amSAN-SAV
9h 26m1 stop
$326American Airlines
Find Deal
Thu, Oct 16 - Mon, Oct 20
Delta Logo
6:55 pm - 11:14 pmCHS-SAN
7h 19m1 stop
Delta Logo
10:30 pm - 10:20 amSAN-CHS
8h 50m1 stop
$337Delta
Find Deal
Sat, Oct 11 - Mon, Oct 13
American Airlines Logo
2:16 pm - 7:24 pmCAE-SAN
8h 08m1 stop
American Airlines Logo
10:31 pm - 9:45 amSAN-CAE
8h 14m1 stop
$339American Airlines
Find Deal
Fri, Oct 24 - Mon, Oct 27
Frontier Logo
5:20 pm - 11:53 pmCLT-SAN
9h 33m1 stop
Frontier Logo
6:35 am - 4:25 pmSAN-CLT
6h 50m1 stop
$348Frontier
Find Deal
Thu, Oct 2 - Sun, Oct 5
Frontier Logo
5:20 pm - 11:53 pmCLT-SAN
9h 33m1 stop
Frontier Logo
10:52 am - 9:00 amSAN-CLT
19h 08m2 stops
$349Frontier
Find Deal
Mon, Oct 6 - Thu, Oct 9

United Airlines flights from South Carolina to San Diego

Our best United Airlines deals on South Carolina to San Diego flight tickets
United Airlines
Oct 25
CAE3:42 pmColumbia Metropolitan
9h 32m
1 stop
SAN10:14 pmSan Diego
Nov 1
SAN10:00 pmSan Diego
9h 59m
1 stop
CAE10:59 amColumbia Metropolitan
$309
Find similar
United Airlines
Oct 25
CAE2:53 pmColumbia Metropolitan
10h 21m
2 stops
SAN10:14 pmSan Diego
Nov 1
SAN10:00 pmSan Diego
9h 59m
1 stop
CAE10:59 amColumbia Metropolitan
$314
Find similar
United Airlines
Oct 25
CAE10:24 amColumbia Metropolitan
11h 06m
2 stops
SAN6:30 pmSan Diego
Nov 1
SAN9:00 amSan Diego
9h 30m
2 stops
CAE9:30 pmColumbia Metropolitan
$319
Find similar

Delta flights from South Carolina to San Diego

Our best Delta deals on South Carolina to San Diego flight tickets
Delta
Oct 21
AGS5:59 pmAugusta Bush Field
8h 15m
1 stop
SAN11:14 pmSan Diego
Oct 27
SAN9:48 pmSan Diego
8h 17m
1 stop
AGS9:05 amAugusta Bush Field
$317
Find similar
Delta
Oct 11
CHS6:55 pmCharleston
7h 19m
1 stop
SAN11:14 pmSan Diego
Oct 13
SAN10:30 pmSan Diego
8h 50m
1 stop
CHS10:20 amCharleston
$337
Find similar
Delta
Mar 3
CHS6:00 amCharleston
9h 19m
1 stop
SAN12:19 pmSan Diego
Mar 4
SAN6:15 amSan Diego
8h 47m
1 stop
CHS6:02 pmCharleston
$355
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

Tue 2/24

12:05 pm-7:34 pm

1 stop10h 29m

San Diego

Tue 3/10

8:55 pm-11:19 am

1 stop11h 24m

$275

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Thu 3/5

12:16 pm-8:08 pm

1 stop10h 52m

San Diego

Mon 3/9

9:22 pm-11:31 am

1 stop11h 09m

$297

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

Sat 10/25

3:42 pm-10:14 pm

1 stop9h 32m

San Diego

Sat 11/1

10:00 pm-10:59 am

1 stop9h 59m

$309

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

Sat 10/25

2:53 pm-10:14 pm

2 stops10h 21m

San Diego

Sat 11/1

10:00 pm-10:59 am

1 stop9h 59m

$314

AugustaSan Diego

AGS - SAN

AGSSAN

Augusta Bush Field

Tue 10/21

5:59 pm-11:14 pm

1 stop8h 15m

San Diego

Mon 10/27

9:48 pm-9:05 am

1 stop8h 17m

$317

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Thu 10/16

12:09 pm-7:29 pm

1 stop10h 20m

San Diego

Mon 10/20

9:27 pm-9:53 am

1 stop9h 26m

$326

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

Sat 10/11

6:55 pm-11:14 pm

1 stop7h 19m

San Diego

Mon 10/13

10:30 pm-10:20 am

1 stop8h 50m

$337

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

Fri 10/24

2:16 pm-7:24 pm

1 stop8h 08m

San Diego

Mon 10/27

10:31 pm-9:45 am

1 stop8h 14m

$339

CharlotteSan Diego

CLT - SAN

CLTSAN

Charlotte Douglas

Thu 10/2

5:20 pm-11:53 pm

1 stop9h 33m

San Diego

Sun 10/5

6:35 am-4:25 pm

1 stop6h 50m

$348

CharlotteSan Diego

CLT - SAN

CLTSAN

Charlotte Douglas

Mon 10/6

5:20 pm-11:53 pm

1 stop9h 33m

San Diego

Thu 10/9

10:52 am-9:00 am

2 stops19h 08m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from South Carolina to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from South Carolina during the month August is also very affordable. Most momondo users find prices during this month for around $370.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from South Carolina to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $437. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $545. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $444. Flights in the morning are often more expensive with an average ticket price of $491.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $407 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from South Carolina for as low as $291 on momondo.

Can stopping save me money on South Carolina to San Diego flights?

You could potentially save up to 8% on your flight if you consider stops on a South Carolina to San Diego flight.

Cheap South Carolina to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to San Diego

Fastest flight time

4h 56m

Direct flights

Every day

Airports in San Diego

1 airport
The fastest flight from South Carolina to San Diego takes 4h 56m
Direct flights go from South Carolina to San Diego every day.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • When did momondo last update prices for flights from South Carolina to San Diego Airport?

    Prices for flights from South Carolina to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to San Diego Airport?

  • How old do you have to be to fly from South Carolina to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to San Diego

Compare and see reviews for airlines that fly from South Carolina to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $70Free CancellationRating
6.3
8,031 reviews
Search Spirit Airlines flights
JetBluePriceFrom $170Free CancellationRating
7.2
2,912 reviews
Search JetBlue flights
DeltaPriceFrom $257Free CancellationRating
7.9
7,971 reviews
Search Delta flights
American AirlinesPriceFrom $268Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $294Free CancellationRating
7.4
8,922 reviews
Search United Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,244 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Poway
Imperial Beach
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from South Carolina.

Can I find flights from South Carolina to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to San Diego?

Once all potential South Carolina to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/22
Wed 10/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States