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Cheap flights from Sioux Falls to San Francisco from $145

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Sioux Falls to San Francisco

Cheap round-trip flights

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American Airlines Logo
2:26 pm - 7:39 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
7h 13m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
4:00 pm - 11:49 pmSFO  San Francisco-FSD Sioux Falls Joe Foss Field
5h 49m1 stop Phoenix Sky Harbor Intl
$321American Airlines
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
5:54 pm - 11:57 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
8h 03m1 stop Dallas/Fort Worth
American Airlines Logo
7:49 am - 5:23 pmSFO  San Francisco-FSD Sioux Falls Joe Foss Field
7h 34m1 stop Dallas/Fort Worth
$321American Airlines
Tue, Oct 27 - Tue, Dec 1
American Airlines Logo
5:58 pm - 11:31 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
7h 33m1 stop Dallas/Fort Worth
American Airlines Logo
4:00 pm - 11:49 pmSFO  San Francisco-FSD Sioux Falls Joe Foss Field
5h 49m1 stop Phoenix Sky Harbor Intl
$321American Airlines
Tue, Dec 8 - Wed, Dec 16
Multiple Airlines Logo
12:00 pm - 9:38 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
35h 38m2 stops Phoenix-Mesa Gateway Santa Ana J. Wayne/Orange Cnty
Multiple Airlines Logo
7:14 pm - 10:58 amSFO  San Francisco-FSD Sioux Falls Joe Foss Field
13h 44m1 stop Las Vegas Harry Reid Intl
$356Multiple Airlines
Sat, Nov 7 - Wed, Nov 11
United Airlines Logo
6:40 pm - 12:53 amFSD  Sioux Falls Joe Foss Field-SFO San Francisco
8h 13m1 stop Chicago O'Hare Intl
United Airlines Logo
4:24 pm - 11:44 pmSFO  San Francisco-FSD Sioux Falls Joe Foss Field
5h 20m1 stop Denver Intl
$359United Airlines
Mon, Nov 23 - Fri, Nov 27
Delta Logo
8:30 am - 12:20 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
5h 50m1 stop Minneapolis St Paul
Delta Logo
8:58 pm - 10:00 amSFO  San Francisco-FSD Sioux Falls Joe Foss Field
11h 02m2 stops Seattle/Tacoma Intl Minneapolis St Paul
$388Delta
Wed, Oct 21 - Mon, Oct 26
Multiple Airlines Logo
10:32 pm - 8:19 amFSD  Sioux Falls Joe Foss Field-SFO San Francisco
11h 47m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
4:43 pm - 7:42 pmSFO  San Francisco-FSD Sioux Falls Joe Foss Field
24h 59m1 stop Phoenix Sky Harbor Intl
$389Multiple Airlines
Mon, Nov 16 - Fri, Nov 20
Multiple Airlines Logo
10:32 pm - 8:19 amFSD  Sioux Falls Joe Foss Field-SFO San Francisco
11h 47m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
8:22 pm - 11:06 amSFO  San Francisco-FSD Sioux Falls Joe Foss Field
36h 44m2 stops Los Angeles Las Vegas Harry Reid Intl
$393Multiple Airlines
Mon, Nov 16 - Fri, Nov 20
Delta Logo
4:09 pm - 11:41 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
9h 32m2 stops Minneapolis St Paul Seattle/Tacoma Intl
Delta Logo
6:15 am - 3:50 pmSFO  San Francisco-FSD Sioux Falls Joe Foss Field
7h 35m1 stop Minneapolis St Paul
$407Delta
Wed, Jan 20 - Sun, Jan 24
United Airlines Logo
3:14 pm - 9:24 pmFSD  Sioux Falls Joe Foss Field-SFO San Francisco
8h 10m1 stop Chicago O'Hare Intl
United Airlines Logo
11:12 pm - 10:32 amSFO  San Francisco-FSD Sioux Falls Joe Foss Field
9h 20m1 stop Chicago O'Hare Intl
$411United Airlines
Sat, Dec 5 - Tue, Dec 8

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American Airlines flights from Sioux Falls to San Francisco

Our best American Airlines deals on Sioux Falls to San Francisco flight tickets
American Airlines
Oct 27
FSD5:54 pmSioux Falls Joe Foss Field
8h 03m
1 stop
SFO11:57 pmSan Francisco
Dec 1
SFO7:49 amSan Francisco
7h 34m
1 stop
FSD5:23 pmSioux Falls Joe Foss Field
$321
American Airlines
Oct 23
FSD5:54 pmSioux Falls Joe Foss Field
7h 12m
1 stop
SFO11:06 pmSan Francisco
Oct 28
SFO5:30 amSan Francisco
9h 53m
1 stop
FSD5:23 pmSioux Falls Joe Foss Field
$330
American Airlines
Oct 1
FSD5:55 pmSioux Falls Joe Foss Field
7h 54m
1 stop
SFO11:49 pmSan Francisco
Oct 6
SFO5:45 amSan Francisco
5h 50m
1 stop
FSD1:35 pmSioux Falls Joe Foss Field
$339

United Airlines flights from Sioux Falls to San Francisco

Our best United Airlines deals on Sioux Falls to San Francisco flight tickets
United Airlines
Nov 23
FSD6:40 pmSioux Falls Joe Foss Field
8h 13m
1 stop
SFO12:53 amSan Francisco
Nov 27
SFO4:24 pmSan Francisco
5h 20m
1 stop
FSD11:44 pmSioux Falls Joe Foss Field
$359
United Airlines
Dec 5
FSD3:14 pmSioux Falls Joe Foss Field
8h 10m
1 stop
SFO9:24 pmSan Francisco
Dec 8
SFO11:12 pmSan Francisco
9h 20m
1 stop
FSD10:32 amSioux Falls Joe Foss Field
$411
United Airlines
Dec 3
FSD9:24 amSioux Falls Joe Foss Field
7h 51m
1 stop
SFO3:15 pmSan Francisco
Dec 6
SFO6:35 amSan Francisco
10h 01m
1 stop
FSD6:36 pmSioux Falls Joe Foss Field
$429

momondo Fare Finder

 
Use the filters below to find and compare flights from Sioux Falls to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Sat 11/7

2:26 pm-7:39 pm

1 stop7h 13m

San Francisco

Wed 11/11

4:00 pm-11:49 pm

1 stop5h 49m

$321

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Tue 10/27

5:54 pm-11:57 pm

1 stop8h 03m

San Francisco

Tue 12/1

7:49 am-5:23 pm

1 stop7h 34m

$321

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Tue 12/8

5:58 pm-11:31 pm

1 stop7h 33m

San Francisco

Wed 12/16

4:00 pm-11:49 pm

1 stop5h 49m

$321

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Sat 11/7

12:00 pm-9:38 pm

2 stops35h 38m

San Francisco

Wed 11/11

7:14 pm-10:58 am

1 stop13h 44m

$356

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Mon 11/23

6:40 pm-12:53 am

1 stop8h 13m

San Francisco

Fri 11/27

4:24 pm-11:44 pm

1 stop5h 20m

$359

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Wed 10/21

8:30 am-12:20 pm

1 stop5h 50m

San Francisco

Mon 10/26

8:58 pm-10:00 am

2 stops11h 02m

$388

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Mon 11/16

10:32 pm-8:19 am

1 stop11h 47m

San Francisco

Fri 11/20

4:43 pm-7:42 pm

1 stop24h 59m

$389

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Mon 11/16

10:32 pm-8:19 am

1 stop11h 47m

San Francisco

Fri 11/20

8:22 pm-11:06 am

2 stops36h 44m

$393

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Wed 1/20

4:09 pm-11:41 pm

2 stops9h 32m

San Francisco

Sun 1/24

6:15 am-3:50 pm

1 stop7h 35m

$407

Sioux FallsSan Francisco

FSD Sioux Falls Joe Foss Field - SFO San Francisco

FSDSFO

Sioux Falls Joe Foss Field

Sat 12/5

3:14 pm-9:24 pm

1 stop8h 10m

San Francisco

Tue 12/8

11:12 pm-10:32 am

1 stop9h 20m

$411

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Sioux Falls to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of April, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $334.

How have Sioux Falls to San Francisco flight prices changed over time?

As of September 2026, prices for Sioux Falls to San Francisco flights are approximately 130% more expensive when compared to flights at the same time last year.

When to book flights from Sioux Falls to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to San Francisco (FSD to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to San Francisco

Best Price Found

$145

Fastest flight time

5h 29m

Direct flights

None
The best one-way flight to San Francisco from Sioux Falls in the past 72 hours is $145. The best round-trip flight deal from Sioux Falls to San Francisco found on momondo in the last 72 hours is $321.
The fastest flight from Sioux Falls to San Francisco takes 5h 29m
There are no direct flights from Sioux Falls to San Francisco. There are no popular flight routes from Sioux Falls to San Francisco.
Search flight deals

Frequently asked questions about flying from Sioux Falls to San Francisco

  • How far is Sioux Falls Joe Foss Field to San Francisco by plane?

    Sioux Falls Joe Foss Field and San Francisco are 1395.8 mi apart from one another. In terms of flight time, this usually takes a little over 5h 29m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to San Francisco Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to San Francisco Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Sioux Falls to San Francisco?

Best airlines flying from Sioux Falls to San Francisco

Compare and see reviews for airlines that fly from Sioux Falls to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $268Free CancellationRating
7.8
8,554 reviews
Search Delta flights
United AirlinesPriceFrom $268Free CancellationRating
7.4
10,189 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.1
12,045 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Bodega Bay
Hayward
Fremont
Berkeley
Walnut Creek
Santa Clara
Sunnyvale
Vallejo
Salinas
Roseville
Half Moon Bay
Sonoma
Daly City
Milpitas
Marina
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to San Francisco?

It is quick and easy to find Sioux Falls to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Sioux Falls to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Sioux Falls which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Sioux Falls to San Francisco?

momondo helps you find the best flight between Sioux Falls and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Sioux Falls to San Francisco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Sioux Falls to San Francisco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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