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Cheap flights from Santo Domingo to San Diego from $254

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to San Diego departing on 4/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santo Domingo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:37 pm - 11:25 pm
SDQ
-
SAN
11h 48m
1 stop
Delta Logo
9:45 pm - 6:34 pm
SAN
-
SDQ
17h 49m
2 stops
$470Delta
Fri, Apr 17 - Tue, Apr 21
United Airlines Logo
6:00 am - 10:30 pm
SDQ
-
SAN
19h 30m
2 stops
United Airlines Logo
4:09 pm - 11:55 am
SAN
-
SDQ
16h 46m
2 stops
$473United Airlines
Fri, Apr 17 - Fri, Apr 24
Delta Logo
2:37 pm - 11:25 pm
SDQ
-
SAN
11h 48m
1 stop
Delta Logo
10:30 pm - 6:34 pm
SAN
-
SDQ
17h 04m
2 stops
$482Delta
Fri, Apr 17 - Fri, Apr 24
Delta Logo
6:05 am - 11:25 pm
SDQ
-
SAN
20h 20m
2 stops
Delta Logo
6:15 am - 12:17 am
SAN
-
SDQ
15h 02m
2 stops
$483Delta
Fri, Apr 17 - Tue, Apr 21
Copa Airlines Logo
8:53 am - 6:30 pm
SDQ
-
SAN
12h 37m
1 stop
Copa Airlines Logo
8:58 pm - 4:15 pm
SAN
-
SDQ
16h 17m
1 stop
$491Copa Airlines
Mon, Jul 27 - Mon, Aug 10
American Airlines Logo
4:00 pm - 11:53 am
SDQ
-
SAN
22h 53m
1 stop
American Airlines Logo
12:53 pm - 9:20 am
SAN
-
SDQ
17h 27m
1 stop
$501American Airlines
Mon, Apr 20 - Tue, May 5
United Airlines Logo
3:20 pm - 9:15 am
SDQ
-
SAN
20h 55m
2 stops
United Airlines Logo
10:20 pm - 2:10 pm
SAN
-
SDQ
12h 50m
1 stop
$505United Airlines
Fri, May 8 - Mon, May 11
American Airlines Logo
5:55 pm - 11:53 am
SDQ
-
SAN
20h 58m
1 stop
American Airlines Logo
9:45 pm - 2:59 pm
SAN
-
SDQ
14h 14m
2 stops
$506American Airlines
Mon, Apr 20 - Tue, May 5
Delta Logo
6:05 am - 10:00 pm
SDQ
-
SAN
18h 55m
2 stops
Delta Logo
6:15 am - 11:55 pm
SAN
-
SDQ
14h 40m
2 stops
$517Delta
Tue, Jun 2 - Tue, Jun 9
JetBlue Logo
5:50 am - 8:04 pm
SDQ
-
SAN
17h 14m
1 stop
JetBlue Logo
8:30 pm - 2:42 pm
SAN
-
SDQ
15h 12m
1 stop
$555JetBlue
Fri, May 8 - Mon, May 11

JetBlue flights from Santo Domingo to San Diego

Our best JetBlue deals on Santo Domingo to San Diego flight tickets
JetBlue
May 8
SDQ5:50 amSanto Domingo Las Americas
17h 14m
1 stop
SAN8:04 pmSan Diego
May 11
SAN8:30 pmSan Diego
15h 12m
1 stop
SDQ2:42 pmSanto Domingo Las Americas
$555
JetBlue
Apr 22
SDQ5:40 amSanto Domingo Las Americas
17h 24m
1 stop
SAN8:04 pmSan Diego
Apr 25
SAN9:15 pmSan Diego
13h 41m
1 stop
SDQ1:56 pmSanto Domingo Las Americas
$598
JetBlue
May 7
SDQ7:26 pmSanto Domingo Las Americas
17h 27m
1 stop
SAN9:53 amSan Diego
May 31
SAN8:45 pmSan Diego
14h 37m
1 stop
SDQ2:22 pmSanto Domingo Las Americas
$672

United Airlines flights from Santo Domingo to San Diego

Our best United Airlines deals on Santo Domingo to San Diego flight tickets
United Airlines
May 8
SDQ6:00 amSanto Domingo Las Americas
14h 24m
2 stops
SAN5:24 pmSan Diego
May 11
SAN10:20 pmSan Diego
12h 50m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
$494
United Airlines
May 8
SDQ6:00 amSanto Domingo Las Americas
14h 24m
2 stops
SAN5:24 pmSan Diego
May 11
SAN6:05 pmSan Diego
17h 05m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$505
United Airlines
Jun 2
SDQ6:00 amSanto Domingo Las Americas
20h 54m
2 stops
SAN11:54 pmSan Diego
Jun 9
SAN9:05 pmSan Diego
11h 50m
1 stop
SDQ11:55 amSanto Domingo Las Americas
$541

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 4/17

2:37 pm-11:25 pm

1 stop11h 48m

San Diego

Tue 4/21

9:45 pm-6:34 pm

2 stops17h 49m

$470

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 4/17

6:00 am-10:30 pm

2 stops19h 30m

San Diego

Fri 4/24

4:09 pm-11:55 am

2 stops16h 46m

$473
Quickest round-trip

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 4/17

2:37 pm-11:25 pm

1 stop11h 48m

San Diego

Fri 4/24

10:30 pm-6:34 pm

2 stops17h 04m

$482

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 4/17

6:05 am-11:25 pm

2 stops20h 20m

San Diego

Tue 4/21

6:15 am-12:17 am

2 stops15h 02m

$483

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Mon 7/27

8:53 am-6:30 pm

1 stop12h 37m

San Diego

Mon 8/10

8:58 pm-4:15 pm

1 stop16h 17m

$491

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Mon 4/20

4:00 pm-11:53 am

1 stop22h 53m

San Diego

Tue 5/5

12:53 pm-9:20 am

1 stop17h 27m

$501

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 5/8

3:20 pm-9:15 am

2 stops20h 55m

San Diego

Mon 5/11

10:20 pm-2:10 pm

1 stop12h 50m

$505

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Mon 4/20

5:55 pm-11:53 am

1 stop20h 58m

San Diego

Tue 5/5

9:45 pm-2:59 pm

2 stops14h 14m

$506

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Tue 6/2

6:05 am-10:00 pm

2 stops18h 55m

San Diego

Tue 6/9

6:15 am-11:55 pm

2 stops14h 40m

$517

Santo DomingoSan Diego

SDQ - SAN

SDQSAN

Santo Domingo Las Americas

Fri 5/8

5:50 am-8:04 pm

1 stop17h 14m

San Diego

Mon 5/11

8:30 pm-2:42 pm

1 stop15h 12m

$555

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Santo Domingo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of February, then departing from Santo Domingo during the month January is also very affordable. Most momondo users find prices during this month for around $500.

Can stopping save me money on Santo Domingo to San Diego flights?

You could potentially save up to 36% on your flight if you consider stops on a Santo Domingo to San Diego flight.

How have Santo Domingo to San Diego flight prices changed over time?

When to book flights from Santo Domingo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to San Diego (SDQ to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to San Diego

Fastest flight time

11h 48m

Direct flights

None
The fastest flight from Santo Domingo to San Diego takes 11h 48m
There are no direct flights from Santo Domingo to San Diego. There are no popular flight routes from Santo Domingo to San Diego.
Search flight deals

  • How far is Santo Domingo Las Americas to San Diego by plane?

    The distance between Santo Domingo Las Americas and San Diego is about 3072.5 mi. Flights usually cover this in 11h 48m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to San Diego Airport?

    Prices for flights from Santo Domingo Las Americas Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to San Diego Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to San Diego Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santo Domingo to San Diego?

Best airlines flying from Santo Domingo to San Diego

Compare and see reviews for airlines that fly from Santo Domingo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $336Free CancellationRating
7.1
11,488 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
Imperial Beach
La Mesa
Borrego Springs
Alpine
Santee
Lemon Grove

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to San Diego?

Finding the right flight to San Diego from Santo Domingo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Santo Domingo to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to San Diego?

momondo helps you find the best flight between Santo Domingo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

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