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Cheap flights from Santo Domingo to San Diego from $289

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to San Diego departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santo Domingo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:47 am - 6:29 pmSDQ  Santo Domingo Las Americas-SAN San Diego
12h 42m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 1:13 pmSAN  San Diego-SDQ Santo Domingo Las Americas
12h 13m1 stop Panama City Tocumen Intl
$569Copa Airlines
Mon, Sep 21 - Mon, Sep 28
Copa Airlines Logo
8:47 am - 6:30 pmSDQ  Santo Domingo Las Americas-SAN San Diego
12h 43m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 4:14 pmSAN  San Diego-SDQ Santo Domingo Las Americas
15h 14m1 stop Panama City Tocumen Intl
$569Copa Airlines
Fri, Oct 2 - Wed, Oct 7
Copa Airlines Logo
8:47 am - 6:29 pmSDQ  Santo Domingo Las Americas-SAN San Diego
12h 42m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 1:12 pmSAN  San Diego-SDQ Santo Domingo Las Americas
12h 12m1 stop Panama City Tocumen Intl
$569Copa Airlines
Wed, Sep 16 - Fri, Oct 16
United Airlines Logo
3:20 pm - 9:49 amSDQ  Santo Domingo Las Americas-SAN San Diego
21h 29m1 stop Newark
United Airlines Logo
2:45 pm - 2:06 pmSAN  San Diego-SDQ Santo Domingo Las Americas
20h 21m1 stop Newark
$581United Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
4:20 pm - 8:59 amSDQ  Santo Domingo Las Americas-SAN San Diego
19h 39m2 stops Miami Charlotte Douglas
American Airlines Logo
9:30 pm - 12:35 pmSAN  San Diego-SDQ Santo Domingo Las Americas
12h 05m1 stop Philadelphia
$585American Airlines
Thu, Oct 1 - Tue, Oct 6
American Airlines Logo
4:20 pm - 8:59 amSDQ  Santo Domingo Las Americas-SAN San Diego
19h 39m2 stops Miami Charlotte Douglas
American Airlines Logo
9:25 pm - 3:20 pmSAN  San Diego-SDQ Santo Domingo Las Americas
14h 55m2 stops Charlotte Douglas Miami
$585American Airlines
Thu, Oct 1 - Tue, Oct 6
United Airlines Logo
6:00 am - 10:27 pmSDQ  Santo Domingo Las Americas-SAN San Diego
19h 27m2 stops Newark Denver Intl
United Airlines Logo
6:50 am - 10:46 pmSAN  San Diego-SDQ Santo Domingo Las Americas
12h 56m2 stops Chicago O'Hare Intl Newark
$585United Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
4:20 pm - 8:59 amSDQ  Santo Domingo Las Americas-SAN San Diego
19h 39m2 stops Miami Charlotte Douglas
American Airlines Logo
12:56 pm - 9:22 amSAN  San Diego-SDQ Santo Domingo Las Americas
17h 26m1 stop Miami
$585American Airlines
Thu, Oct 1 - Tue, Oct 6
United Airlines Logo
6:00 am - 8:39 pmSDQ  Santo Domingo Las Americas-SAN San Diego
17h 39m2 stops Newark Denver Intl
United Airlines Logo
10:20 pm - 2:06 pmSAN  San Diego-SDQ Santo Domingo Las Americas
12h 46m1 stop Newark
$585United Airlines
Fri, Oct 23 - Tue, Oct 27
Copa Airlines Logo
8:48 am - 6:30 pmSDQ  Santo Domingo Las Americas-SAN San Diego
12h 42m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 10:55 amSAN  San Diego-SDQ Santo Domingo Las Americas
9h 55m1 stop Panama City Tocumen Intl
$632Copa Airlines
Wed, Aug 26 - Mon, Aug 31

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United Airlines flights from Santo Domingo to San Diego

Our best United Airlines deals on Santo Domingo to San Diego flight tickets
United Airlines
Oct 23
SDQ3:20 pmSanto Domingo Las Americas
21h 29m
1 stop
SAN9:49 amSan Diego
Oct 27
SAN2:45 pmSan Diego
20h 21m
1 stop
SDQ2:06 pmSanto Domingo Las Americas
$581
United Airlines
Oct 16
SDQ6:00 amSanto Domingo Las Americas
17h 08m
2 stops
SAN8:08 pmSan Diego
Oct 17
SAN10:20 pmSan Diego
12h 50m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
$656
United Airlines
Oct 2
SDQ1:10 pmSanto Domingo Las Americas
32h 25m
3 stops
SAN6:35 pmSan Diego
Oct 7
SAN10:13 amSan Diego
24h 57m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$711

Copa Airlines flights from Santo Domingo to San Diego

Our best Copa Airlines deals on Santo Domingo to San Diego flight tickets
Copa Airlines
Sep 16
SDQ8:47 amSanto Domingo Las Americas
12h 42m
1 stop
SAN6:29 pmSan Diego
Oct 16
SAN10:00 pmSan Diego
12h 12m
1 stop
SDQ1:12 pmSanto Domingo Las Americas
$569
Copa Airlines
Aug 26
SDQ8:48 amSanto Domingo Las Americas
12h 42m
1 stop
SAN6:30 pmSan Diego
Aug 31
SAN10:00 pmSan Diego
9h 55m
1 stop
SDQ10:55 amSanto Domingo Las Americas
$632
Copa Airlines
Aug 16
SDQ6:07 amSanto Domingo Las Americas
15h 23m
1 stop
SAN6:30 pmSan Diego
Aug 31
SAN10:00 pmSan Diego
9h 55m
1 stop
SDQ10:55 amSanto Domingo Las Americas
$839

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Mon 9/21

8:47 am-6:29 pm

1 stop12h 42m

San Diego

Mon 9/28

10:00 pm-1:13 pm

1 stop12h 13m

$569

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Fri 10/2

8:47 am-6:30 pm

1 stop12h 43m

San Diego

Wed 10/7

10:00 pm-4:14 pm

1 stop15h 14m

$569

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Wed 9/16

8:47 am-6:29 pm

1 stop12h 42m

San Diego

Fri 10/16

10:00 pm-1:12 pm

1 stop12h 12m

$569

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Fri 10/23

3:20 pm-9:49 am

1 stop21h 29m

San Diego

Tue 10/27

2:45 pm-2:06 pm

1 stop20h 21m

$581

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Thu 10/1

4:20 pm-8:59 am

2 stops19h 39m

San Diego

Tue 10/6

9:30 pm-12:35 pm

1 stop12h 05m

$585

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Thu 10/1

4:20 pm-8:59 am

2 stops19h 39m

San Diego

Tue 10/6

9:25 pm-3:20 pm

2 stops14h 55m

$585

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Fri 10/23

6:00 am-10:27 pm

2 stops19h 27m

San Diego

Tue 10/27

6:50 am-10:46 pm

2 stops12h 56m

$585

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Thu 10/1

4:20 pm-8:59 am

2 stops19h 39m

San Diego

Tue 10/6

12:56 pm-9:22 am

1 stop17h 26m

$585

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Fri 10/23

6:00 am-8:39 pm

2 stops17h 39m

San Diego

Tue 10/27

10:20 pm-2:06 pm

1 stop12h 46m

$585
Quickest round-trip

Santo DomingoSan Diego

SDQ Santo Domingo Las Americas - SAN San Diego

SDQSAN

Santo Domingo Las Americas

Wed 8/26

8:48 am-6:30 pm

1 stop12h 42m

San Diego

Mon 8/31

10:00 pm-10:55 am

1 stop9h 55m

$632

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of April, then departing from Santo Domingo during the month February is also very affordable. Most momondo users find prices during this month for around $339.

Can stopping save me money on Santo Domingo to San Diego flights?

You could potentially save up to 47% on your flight if you consider stops on a Santo Domingo to San Diego flight.

How have Santo Domingo to San Diego flight prices changed over time?

When to book flights from Santo Domingo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to San Diego (SDQ to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to San Diego

Fastest flight time

12h 42m

Direct flights

None
The fastest flight from Santo Domingo to San Diego takes 12h 42m
There are no direct flights from Santo Domingo to San Diego. There are no popular flight routes from Santo Domingo to San Diego.
Search flight deals

Frequently asked questions about flying from Santo Domingo to San Diego

  • How far is Santo Domingo Las Americas to San Diego by plane?

    The distance between Santo Domingo Las Americas and San Diego is about 3072.5 mi. Flights usually cover this in 12h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to San Diego Airport?

    Prices for flights from Santo Domingo Las Americas Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to San Diego Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to San Diego Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santo Domingo to San Diego?

Best airlines flying from Santo Domingo to San Diego

Compare and see reviews for airlines that fly from Santo Domingo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $336Free CancellationRating
7.1
11,913 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $558Free CancellationRating
7.6
1,557 reviews
Search Copa Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
National City
Julian
La Mesa
Poway
San Ysidro
Imperial Beach
Santee
Borrego Springs
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to San Diego?

Finding the right flight to San Diego from Santo Domingo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Santo Domingo to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to San Diego?

momondo helps you find the best flight between Santo Domingo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

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