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Cheap flights from Santo Domingo to San Antonio from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to San Antonio departing on 4/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santo Domingo to San Antonio

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
Spirit Airlines Logo
6:07 am - 1:29 pm
SAT
-
SDQ
6h 22m
1 stop
$421Spirit Airlines
Thu, Apr 30 - Thu, May 7
Spirit Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Spirit Airlines Logo
6:07 am - 1:29 pm
SAT
-
SDQ
6h 22m
1 stop
$458Spirit Airlines
Sat, May 16 - Fri, May 29
Spirit Airlines Logo
2:35 pm - 11:51 pm
SDQ
-
SAT
10h 16m
1 stop
Spirit Airlines Logo
2:12 pm - 1:29 pm
SAT
-
SDQ
22h 17m
2 stops
$505Spirit Airlines
Thu, Apr 30 - Thu, May 7
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
6:07 am - 5:29 am
SAT
-
SDQ
22h 22m
2 stops
$537Multiple Airlines
Sat, May 16 - Mon, Jun 1
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
12:00 pm - 5:59 am
SAT
-
SDQ
16h 59m
2 stops
$545Multiple Airlines
Sat, May 16 - Wed, May 27
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
2:12 pm - 7:18 pm
SAT
-
SDQ
28h 06m
2 stops
$546Multiple Airlines
Sat, May 16 - Sat, May 30
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
9:55 am - 5:29 am
SAT
-
SDQ
18h 34m
2 stops
$550Multiple Airlines
Sat, May 16 - Thu, May 28
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
12:00 pm - 5:59 am
SAT
-
SDQ
16h 59m
2 stops
$554Multiple Airlines
Thu, May 14 - Fri, May 29
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
2:12 pm - 7:18 pm
SAT
-
SDQ
28h 06m
2 stops
$555Multiple Airlines
Thu, May 14 - Sat, May 30
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
SAT
10h 24m
1 stop
Multiple Airlines Logo
9:55 am - 4:29 pm
SAT
-
SDQ
29h 34m
2 stops
$556Multiple Airlines
Thu, May 14 - Sun, May 31

Spirit Airlines flights from Santo Domingo to San Antonio

Our best Spirit Airlines deals on Santo Domingo to San Antonio flight tickets
Spirit Airlines
Apr 30
SDQ2:35 pmSanto Domingo Las Americas
10h 16m
1 stop
SAT11:51 pmSan Antonio
May 7
SAT6:07 amSan Antonio
6h 22m
1 stop
SDQ1:29 pmSanto Domingo Las Americas
$421
Spirit Airlines
May 16
SDQ2:35 pmSanto Domingo Las Americas
10h 24m
1 stop
SAT11:59 pmSan Antonio
May 29
SAT6:07 amSan Antonio
6h 22m
1 stop
SDQ1:29 pmSanto Domingo Las Americas
$458
Spirit Airlines
Apr 30
SDQ2:35 pmSanto Domingo Las Americas
10h 16m
1 stop
SAT11:51 pmSan Antonio
May 7
SAT2:12 pmSan Antonio
22h 17m
2 stops
SDQ1:29 pmSanto Domingo Las Americas
$505

United Airlines flights from Santo Domingo to San Antonio

Our best United Airlines deals on Santo Domingo to San Antonio flight tickets
United Airlines
Apr 3
SDQ3:20 pmSanto Domingo Las Americas
22h 04m
2 stops
SAT12:24 pmSan Antonio
Apr 7
SAT5:50 pmSan Antonio
19h 20m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$619
United Airlines
Apr 3
SDQ6:00 amSanto Domingo Las Americas
16h 03m
2 stops
SAT9:03 pmSan Antonio
Apr 7
SAT5:50 pmSan Antonio
19h 20m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$706
United Airlines
Apr 3
SDQ6:00 amSanto Domingo Las Americas
14h 48m
2 stops
SAT7:48 pmSan Antonio
Apr 7
SAT12:15 pmSan Antonio
9h 31m
1 stop
SDQ10:46 pmSanto Domingo Las Americas
$905

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 4/30

2:35 pm-11:51 pm

1 stop10h 16m

San Antonio

Thu 5/7

6:07 am-1:29 pm

1 stop6h 22m

$421

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Sat 5/16

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Fri 5/29

6:07 am-1:29 pm

1 stop6h 22m

$458

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 4/30

2:35 pm-11:51 pm

1 stop10h 16m

San Antonio

Thu 5/7

2:12 pm-1:29 pm

2 stops22h 17m

$505

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Sat 5/16

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Mon 6/1

6:07 am-5:29 am

2 stops22h 22m

$537

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Sat 5/16

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Wed 5/27

12:00 pm-5:59 am

2 stops16h 59m

$545

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Sat 5/16

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Sat 5/30

2:12 pm-7:18 pm

2 stops28h 06m

$546

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Sat 5/16

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Thu 5/28

9:55 am-5:29 am

2 stops18h 34m

$550

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 5/14

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Fri 5/29

12:00 pm-5:59 am

2 stops16h 59m

$554

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 5/14

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Sat 5/30

2:12 pm-7:18 pm

2 stops28h 06m

$555

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 5/14

2:35 pm-11:59 pm

1 stop10h 24m

San Antonio

Sun 5/31

9:55 am-4:29 pm

2 stops29h 34m

$556

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to San Antonio from

How to get the cheapest flight ticket from Santo Domingo to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and San Antonio?

Can stopping save me money on Santo Domingo to San Antonio flights?

You could potentially save up to 3% on your flight if you consider stops on a Santo Domingo to San Antonio flight.

How have Santo Domingo to San Antonio flight prices changed over time?

As of March 2026, prices for Santo Domingo to San Antonio flights are approximately 40% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to San Antonio (SDQ to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to San Antonio

Fastest flight time

15h 17m

Direct flights

None
The fastest flight from Santo Domingo to San Antonio takes 15h 17m
There are no direct flights from Santo Domingo to San Antonio. There are no popular flight routes from Santo Domingo to San Antonio.
Search flight deals

  • How far is Santo Domingo Las Americas to San Antonio by plane?

    The straight-line distance from Santo Domingo Las Americas to San Antonio is 1947.2 mi. Typically, this will take 15h 17m by plane in normal conditions.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to San Antonio Airport?

    Prices for flights from Santo Domingo Las Americas Airport to San Antonio Airport are updated daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to San Antonio Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to San Antonio Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The necessary travel and health documents for your San Antonio Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santo Domingo to San Antonio?

Best airlines flying from Santo Domingo to San Antonio

Compare and see reviews for airlines that fly from Santo Domingo to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $461Free CancellationRating
7.1
11,488 reviews
Search American Airlines flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville
Boerne
Pleasanton
Schertz

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to San Antonio?

Finding the right flight to San Antonio from Santo Domingo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Antonio quick and easy, saving you time and money.

Can I find flights from Santo Domingo to San Antonio with flexible booking policies on momondo?

Flights from Santo Domingo to San Antonio with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santo Domingo to San Antonio?

momondo helps you find the best flight between Santo Domingo and San Antonio by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to San Antonio right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to San Antonio now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Antonio and let you know when they change.

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