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Cheap flights from Santo Domingo to San Antonio from $369

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to San Antonio departing on 1/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santo Domingo to San Antonio

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:30 am - 10:03 pmSDQ  Santo Domingo Las Americas-SAT San Antonio
13h 33m1 stop Miami
American Airlines Logo
5:10 am - 1:33 pmSAT  San Antonio-SDQ Santo Domingo Las Americas
7h 23m1 stop Miami
$670American Airlines
Tue, Sep 15 - Tue, Oct 13
American Airlines Logo
10:21 am - 10:03 pmSDQ  Santo Domingo Las Americas-SAT San Antonio
12h 42m1 stop Miami
American Airlines Logo
5:14 am - 1:11 pmSAT  San Antonio-SDQ Santo Domingo Las Americas
6h 57m1 stop Miami
$672American Airlines
Thu, Sep 24 - Thu, Oct 1
United Airlines Logo
6:00 am - 10:45 amSDQ  Santo Domingo Las Americas-SAT San Antonio
29h 45m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
5:30 pm - 2:10 pmSAT  San Antonio-SDQ Santo Domingo Las Americas
19h 40m2 stops Chicago O'Hare Intl Newark
$675United Airlines
Tue, Sep 15 - Tue, Oct 13
United Airlines Logo
6:00 am - 10:45 amSDQ  Santo Domingo Las Americas-SAT San Antonio
29h 45m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
4:17 pm - 2:10 pmSAT  San Antonio-SDQ Santo Domingo Las Americas
20h 53m2 stops Houston George Bush Intcntl Newark
$675United Airlines
Tue, Sep 15 - Tue, Oct 13
American Airlines Logo
2:15 pm - 10:03 pmSDQ  Santo Domingo Las Americas-SAT San Antonio
8h 48m1 stop Miami
American Airlines Logo
3:00 pm - 9:22 amSAT  San Antonio-SDQ Santo Domingo Las Americas
17h 22m2 stops Dallas/Fort Worth Miami
$675American Airlines
Tue, Sep 15 - Tue, Oct 13
United Airlines Logo
6:00 am - 8:38 amSDQ  Santo Domingo Las Americas-SAT San Antonio
27h 38m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
11:47 am - 2:10 pmSAT  San Antonio-SDQ Santo Domingo Las Americas
25h 23m2 stops Houston George Bush Intcntl Newark
$675United Airlines
Thu, Oct 8 - Mon, Oct 12
United Airlines Logo
6:00 am - 9:31 pmSDQ  Santo Domingo Las Americas-SAT San Antonio
16h 31m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
5:33 pm - 11:55 amSAT  San Antonio-SDQ Santo Domingo Las Americas
17h 22m2 stops Chicago O'Hare Intl Newark
$681United Airlines
Thu, Oct 1 - Sat, Oct 10
United Airlines Logo
3:20 pm - 11:41 amSDQ  Santo Domingo Las Americas-SAT San Antonio
21h 21m1 stop Newark
United Airlines Logo
4:17 pm - 11:55 amSAT  San Antonio-SDQ Santo Domingo Las Americas
18h 38m2 stops Houston George Bush Intcntl Newark
$681United Airlines
Thu, Oct 1 - Sat, Oct 10
United Airlines Logo
6:00 am - 8:38 amSDQ  Santo Domingo Las Americas-SAT San Antonio
27h 38m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
11:47 am - 2:10 pmSAT  San Antonio-SDQ Santo Domingo Las Americas
25h 23m2 stops Houston George Bush Intcntl Newark
$698United Airlines
Thu, Oct 8 - Mon, Oct 12
United Airlines Logo
1:10 pm - 3:53 pmSDQ  Santo Domingo Las Americas-SAT San Antonio
27h 43m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
9:48 am - 11:55 amSAT  San Antonio-SDQ Santo Domingo Las Americas
25h 07m2 stops Houston George Bush Intcntl Newark
$737United Airlines
Sun, Sep 27 - Wed, Oct 7

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American Airlines flights from Santo Domingo to San Antonio

Our best American Airlines deals on Santo Domingo to San Antonio flight tickets
American Airlines
Sep 15
SDQ9:30 amSanto Domingo Las Americas
13h 33m
1 stop
SAT10:03 pmSan Antonio
Oct 13
SAT5:10 amSan Antonio
7h 23m
1 stop
SDQ1:33 pmSanto Domingo Las Americas
$670
American Airlines
Sep 24
SDQ10:21 amSanto Domingo Las Americas
12h 42m
1 stop
SAT10:03 pmSan Antonio
Oct 1
SAT5:14 amSan Antonio
6h 57m
1 stop
SDQ1:11 pmSanto Domingo Las Americas
$672
American Airlines
Dec 23
SDQ3:51 pmSanto Domingo Las Americas
9h 22m
1 stop
SAT11:13 pmSan Antonio
Jan 6
SAT5:10 amSan Antonio
7h 00m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
$676

United Airlines flights from Santo Domingo to San Antonio

Our best United Airlines deals on Santo Domingo to San Antonio flight tickets
United Airlines
Sep 15
SDQ6:00 amSanto Domingo Las Americas
29h 45m
2 stops
SAT10:45 amSan Antonio
Oct 13
SAT4:17 pmSan Antonio
20h 53m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$675
United Airlines
Oct 1
SDQ3:20 pmSanto Domingo Las Americas
21h 21m
1 stop
SAT11:41 amSan Antonio
Oct 10
SAT4:17 pmSan Antonio
18h 38m
2 stops
SDQ11:55 amSanto Domingo Las Americas
$681
United Airlines
Oct 8
SDQ6:00 amSanto Domingo Las Americas
27h 38m
2 stops
SAT8:38 amSan Antonio
Oct 12
SAT11:47 amSan Antonio
25h 23m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$698

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Tue 9/15

9:30 am-10:03 pm

1 stop13h 33m

San Antonio

Tue 10/13

5:10 am-1:33 pm

1 stop7h 23m

$670
Quickest round-trip

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Thu 9/24

10:21 am-10:03 pm

1 stop12h 42m

San Antonio

Thu 10/1

5:14 am-1:11 pm

1 stop6h 57m

$672

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Tue 9/15

6:00 am-10:45 am

2 stops29h 45m

San Antonio

Tue 10/13

5:30 pm-2:10 pm

2 stops19h 40m

$675

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Tue 9/15

6:00 am-10:45 am

2 stops29h 45m

San Antonio

Tue 10/13

4:17 pm-2:10 pm

2 stops20h 53m

$675

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Tue 9/15

2:15 pm-10:03 pm

1 stop8h 48m

San Antonio

Tue 10/13

3:00 pm-9:22 am

2 stops17h 22m

$675

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Thu 10/8

6:00 am-8:38 am

2 stops27h 38m

San Antonio

Mon 10/12

11:47 am-2:10 pm

2 stops25h 23m

$675

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Thu 10/1

6:00 am-9:31 pm

2 stops16h 31m

San Antonio

Sat 10/10

5:33 pm-11:55 am

2 stops17h 22m

$681

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Thu 10/1

3:20 pm-11:41 am

1 stop21h 21m

San Antonio

Sat 10/10

4:17 pm-11:55 am

2 stops18h 38m

$681

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Thu 10/8

6:00 am-8:38 am

2 stops27h 38m

San Antonio

Mon 10/12

11:47 am-2:10 pm

2 stops25h 23m

$698

Santo DomingoSan Antonio

SDQ Santo Domingo Las Americas - SAT San Antonio

SDQSAT

Santo Domingo Las Americas

Sun 9/27

1:10 pm-3:53 pm

2 stops27h 43m

San Antonio

Wed 10/7

9:48 am-11:55 am

2 stops25h 07m

$737

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to San Antonio

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Can stopping save me money on Santo Domingo to San Antonio flights?

You could potentially save up to 45% on your flight if you consider stops on a Santo Domingo to San Antonio flight.

How have Santo Domingo to San Antonio flight prices changed over time?

When to book flights from Santo Domingo to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to San Antonio (SDQ to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to San Antonio

Fastest flight time

10h 35m

Direct flights

None
The fastest flight from Santo Domingo to San Antonio takes 10h 35m
There are no direct flights from Santo Domingo to San Antonio. There are no popular flight routes from Santo Domingo to San Antonio.
Search flight deals

Frequently asked questions about flying from Santo Domingo to San Antonio

  • How far is Santo Domingo Las Americas to San Antonio by plane?

    The straight-line distance from Santo Domingo Las Americas to San Antonio is 1947.2 mi. Typically, this will take 10h 35m by plane in normal conditions.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to San Antonio Airport?

    Prices for flights from Santo Domingo Las Americas Airport to San Antonio Airport are updated daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to San Antonio Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to San Antonio Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The necessary travel and health documents for your San Antonio Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santo Domingo to San Antonio?

Best airlines flying from Santo Domingo to San Antonio

Compare and see reviews for airlines that fly from Santo Domingo to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $531Free CancellationRating
7.1
11,904 reviews
Search American Airlines flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Pleasanton
Kerrville
Boerne
Schertz

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to San Antonio?

Finding the right flight to San Antonio from Santo Domingo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Antonio quick and easy, saving you time and money.

Can I find flights from Santo Domingo to San Antonio with flexible booking policies on momondo?

Flights from Santo Domingo to San Antonio with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santo Domingo to San Antonio?

momondo helps you find the best flight between Santo Domingo and San Antonio by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to San Antonio right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to San Antonio now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Antonio and let you know when they change.

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