Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santiago to San Francisco from $457

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
11:55 pm - 11:55 pm
SCL
-
SFO
27h 00m2 stops
Avianca Logo
11:55 pm - 4:15 am
SFO
-
SCL
25h 20m2 stops
$530Avianca
Wed, Apr 15 - Thu, May 14
LATAM Airlines Logo
12:20 am - 7:19 pm
SCL
-
SFO
22h 59m2 stops
LATAM Airlines Logo
8:00 am - 7:40 am
SFO
-
SCL
19h 40m1 stop
$535LATAM Airlines
Thu, Mar 12 - Tue, Mar 17
American Airlines Logo
10:35 pm - 11:02 am
SCL
-
SFO
17h 27m1 stop
American Airlines Logo
8:00 am - 8:15 am
SFO
-
SCL
19h 15m1 stop
$536American Airlines
Mon, Jan 26 - Wed, Feb 4
American Airlines Logo
10:30 pm - 7:12 pm
SCL
-
SFO
25h 42m1 stop
American Airlines Logo
11:35 pm - 8:05 am
SFO
-
SCL
27h 30m1 stop
$537American Airlines
Sat, Feb 7 - Tue, Mar 3
American Airlines Logo
10:35 pm - 11:02 am
SCL
-
SFO
17h 27m1 stop
American Airlines Logo
7:00 am - 8:15 am
SFO
-
SCL
20h 15m1 stop
$539American Airlines
Mon, Jan 26 - Wed, Feb 4
American Airlines Logo
10:30 pm - 3:05 pm
SCL
-
SFO
21h 35m2 stops
American Airlines Logo
10:11 am - 9:00 am
SFO
-
SCL
17h 49m2 stops
$540American Airlines
Thu, Jan 29 - Sun, Feb 1
American Airlines Logo
10:35 pm - 1:50 pm
SCL
-
SFO
20h 15m2 stops
American Airlines Logo
7:00 am - 8:15 am
SFO
-
SCL
20h 15m1 stop
$541American Airlines
Mon, Jan 26 - Wed, Feb 4
LATAM Airlines Logo
11:10 pm - 11:04 pm
SCL
-
SFO
28h 54m2 stops
LATAM Airlines Logo
6:28 pm - 7:40 am
SFO
-
SCL
33h 12m2 stops
$542LATAM Airlines
Fri, Feb 13 - Sat, Mar 14
LATAM Airlines Logo
11:10 pm - 10:54 pm
SCL
-
SFO
28h 44m2 stops
LATAM Airlines Logo
5:55 am - 7:40 am
SFO
-
SCL
20h 45m2 stops
$544LATAM Airlines
Mon, Jan 26 - Wed, Feb 4
Multiple Airlines Logo
7:15 am - 11:16 pm
SCL
-
SFO
19h 01m2 stops
Multiple Airlines Logo
10:57 am - 5:35 am
SFO
-
SCL
15h 38m1 stop
$545Multiple Airlines
Wed, Apr 15 - Thu, May 14

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Apr 15
SCL11:55 pmSantiago Arturo Merino Benitez
27h 00m
2 stops
SFO11:55 pmSan Francisco
May 14
SFO11:55 pmSan Francisco
25h 20m
2 stops
SCL4:15 amSantiago Arturo Merino Benitez
$530
Avianca
Apr 21
SCL6:10 amSantiago Arturo Merino Benitez
20h 45m
2 stops
SFO11:55 pmSan Francisco
May 4
SFO11:55 pmSan Francisco
19h 35m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
$531
Avianca
Feb 23
SCL4:25 pmSantiago Arturo Merino Benitez
35h 55m
2 stops
SFO11:20 pmSan Francisco
Mar 2
SFO11:10 pmSan Francisco
25h 20m
2 stops
SCL5:30 amSantiago Arturo Merino Benitez
$565

American Airlines flights from Santiago to San Francisco

Our best American Airlines deals on Santiago to San Francisco flight tickets
American Airlines
Jan 26
SCL10:35 pmSantiago Arturo Merino Benitez
17h 27m
1 stop
SFO11:02 amSan Francisco
Feb 3
SFO12:17 amSan Francisco
26h 58m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$536
American Airlines
Jan 26
SCL10:35 pmSantiago Arturo Merino Benitez
17h 27m
1 stop
SFO11:02 amSan Francisco
Feb 4
SFO7:00 amSan Francisco
20h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$539
American Airlines
Jan 29
SCL10:30 pmSantiago Arturo Merino Benitez
21h 35m
2 stops
SFO3:05 pmSan Francisco
Feb 1
SFO10:11 amSan Francisco
17h 49m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
$540

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 11, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 4/15

11:55 pm-11:55 pm

2 stops27h 00m

San Francisco

Thu 5/14

11:55 pm-4:15 am

2 stops25h 20m

$530

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 3/12

12:20 am-7:19 pm

2 stops22h 59m

San Francisco

Tue 3/17

8:00 am-7:40 am

1 stop19h 40m

$535

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 1/26

10:35 pm-11:02 am

1 stop17h 27m

San Francisco

Wed 2/4

8:00 am-8:15 am

1 stop19h 15m

$536

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sat 2/7

10:30 pm-7:12 pm

1 stop25h 42m

San Francisco

Tue 3/3

11:35 pm-8:05 am

1 stop27h 30m

$537

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 1/26

10:35 pm-11:02 am

1 stop17h 27m

San Francisco

Wed 2/4

7:00 am-8:15 am

1 stop20h 15m

$539

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 1/29

10:30 pm-3:05 pm

2 stops21h 35m

San Francisco

Sun 2/1

10:11 am-9:00 am

2 stops17h 49m

$540

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 1/26

10:35 pm-1:50 pm

2 stops20h 15m

San Francisco

Wed 2/4

7:00 am-8:15 am

1 stop20h 15m

$541

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 2/13

11:10 pm-11:04 pm

2 stops28h 54m

San Francisco

Sat 3/14

6:28 pm-7:40 am

2 stops33h 12m

$542

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 1/26

11:10 pm-10:54 pm

2 stops28h 44m

San Francisco

Wed 2/4

5:55 am-7:40 am

2 stops20h 45m

$544

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 4/15

7:15 am-11:16 pm

2 stops19h 01m

San Francisco

Thu 5/14

10:57 am-5:35 am

1 stop15h 38m

$545

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $570.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $652 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $575 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 13% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of January 2026, prices for Santiago to San Francisco flights are approximately 4% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Fastest flight time

15h 23m

Direct flights

None
The fastest flight from Santiago to San Francisco takes 15h 23m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5935.3 mi. 15h 23m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $408Free CancellationRating
6.6
2,491 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.2
11,100 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $511Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $518Free CancellationRating
7.5
1,901 reviews
Search LATAM Airlines flights
DeltaPriceFrom $554Free CancellationRating
7.9
8,039 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
9,145 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Santa Clara
Berkeley
Walnut Creek
Fremont
Half Moon Bay
Daly City
Vallejo
Livermore
Salinas
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 2/10
Tue 2/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States