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Cheap flights from Santiago to San Francisco from $338

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
11:55 pm - 5:02 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
21h 07m2 stops Miami Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:00 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
18h 35m2 stops Atlanta Hartsfield-Jackson Miami
$669LATAM Airlines
Tue, Oct 20 - Tue, Nov 10
LATAM Airlines Logo
11:55 pm - 3:59 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 04m2 stops Miami Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:00 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 35m2 stops Atlanta Hartsfield-Jackson Miami
$670LATAM Airlines
Mon, Oct 19 - Wed, Oct 28
Avianca Logo
1:30 am - 11:55 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
26h 25m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 5:45 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
25h 50m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$676Avianca
Wed, Sep 23 - Thu, Oct 1
Avianca Logo
7:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 12:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$712Avianca
Fri, Oct 9 - Fri, Oct 16
Multiple Airlines Logo
9:50 pm - 10:36 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
17h 46m1 stop Atlanta Hartsfield-Jackson
Multiple Airlines Logo
6:00 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 35m1 stop Los Angeles
$712Multiple Airlines
Fri, Dec 11 - Sat, Mar 20
Copa Airlines Logo
3:19 am - 11:12 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
24h 53m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:36 pm - 12:18 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
23h 42m1 stop Panama City Tocumen Intl
$713Copa Airlines
Wed, Nov 25 - Sun, Dec 6
Copa Airlines Logo
3:19 am - 5:25 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 06m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:55 pm - 12:04 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
24h 09m1 stop Panama City Tocumen Intl
$713Copa Airlines
Thu, Dec 10 - Mon, Mar 29
Delta Logo
11:55 pm - 3:59 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 04m2 stops Miami Atlanta Hartsfield-Jackson
Delta Logo
5:13 pm - 7:45 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
22h 32m2 stops Salt Lake City Miami
$716Delta
Mon, Oct 19 - Wed, Oct 21
Delta Logo
11:55 pm - 3:59 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 04m2 stops Miami Atlanta Hartsfield-Jackson
Delta Logo
2:08 pm - 3:00 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 52m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
$716Delta
Mon, Oct 19 - Sat, Oct 24
Multiple Airlines Logo
9:55 pm - 9:49 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
28h 54m2 stops Lima J Chavez Intl Los Angeles
Multiple Airlines Logo
8:00 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
16h 35m1 stop Los Angeles
$719Multiple Airlines
Sat, Jan 23 - Sun, Feb 21

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American Airlines flights from Santiago to San Francisco

Our best American Airlines deals on Santiago to San Francisco flight tickets
American Airlines
Oct 15
SCL9:30 pmSantiago Arturo Merino Benitez
19h 05m
2 stops
SFO12:35 pmSan Francisco
Oct 28
SFO11:39 amSan Francisco
16h 56m
1 stop
SCL8:35 amSantiago Arturo Merino Benitez
$718
American Airlines
Dec 17
SCL10:15 pmSantiago Arturo Merino Benitez
26h 03m
1 stop
SFO7:18 pmSan Francisco
Jan 5
SFO5:30 amSan Francisco
21h 15m
1 stop
SCL7:45 amSantiago Arturo Merino Benitez
$725
American Airlines
Oct 19
SCL9:30 pmSantiago Arturo Merino Benitez
16h 59m
1 stop
SFO10:29 amSan Francisco
Oct 21
SFO11:39 amSan Francisco
16h 31m
1 stop
SCL8:10 amSantiago Arturo Merino Benitez
$728

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Sep 23
SCL1:30 amSantiago Arturo Merino Benitez
26h 25m
2 stops
SFO11:55 pmSan Francisco
Oct 1
SFO11:55 pmSan Francisco
25h 50m
2 stops
SCL5:45 amSantiago Arturo Merino Benitez
$676
Avianca
Oct 9
SCL7:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Oct 16
SFO11:55 pmSan Francisco
20h 25m
2 stops
SCL12:20 amSantiago Arturo Merino Benitez
$712
Avianca
Oct 11
SCL7:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Oct 17
SFO11:55 pmSan Francisco
20h 25m
2 stops
SCL12:20 amSantiago Arturo Merino Benitez
$714

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/20

11:55 pm-5:02 pm

2 stops21h 07m

San Francisco

Tue 11/10

6:00 am-5:35 am

2 stops18h 35m

$669

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 10/19

11:55 pm-3:59 pm

2 stops20h 04m

San Francisco

Wed 10/28

6:00 am-5:35 am

2 stops19h 35m

$670

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 9/23

1:30 am-11:55 pm

2 stops26h 25m

San Francisco

Thu 10/1

11:55 pm-5:45 am

2 stops25h 50m

$676

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/9

7:40 am-10:35 pm

2 stops18h 55m

San Francisco

Fri 10/16

11:55 pm-12:20 am

2 stops20h 25m

$712
Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 12/11

9:50 pm-10:36 am

1 stop17h 46m

San Francisco

Sat 3/20

6:00 am-5:35 am

1 stop19h 35m

$712

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 11/25

3:19 am-11:12 pm

1 stop24h 53m

San Francisco

Sun 12/6

7:36 pm-12:18 am

1 stop23h 42m

$713

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/10

3:19 am-5:25 pm

1 stop19h 06m

San Francisco

Mon 3/29

7:55 pm-12:04 am

1 stop24h 09m

$713

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 10/19

11:55 pm-3:59 pm

2 stops20h 04m

San Francisco

Wed 10/21

5:13 pm-7:45 pm

2 stops22h 32m

$716

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 10/19

11:55 pm-3:59 pm

2 stops20h 04m

San Francisco

Sat 10/24

2:08 pm-3:00 pm

2 stops20h 52m

$716

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Sat 1/23

9:55 pm-9:49 pm

2 stops28h 54m

San Francisco

Sun 2/21

8:00 am-5:35 am

1 stop16h 35m

$719

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $589 to $861.
The lowest price recently found on this route was $669.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $578.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $666 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $605 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 34% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of August 2026, prices for Santiago to San Francisco flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found

$338

Fastest flight time

15h 17m

Direct flights

None
The best one-way flight to San Francisco from Santiago in the past 72 hours is $338. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $669.
The fastest flight from Santiago to San Francisco takes 15h 17m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 15h 17m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,552 reviews
Search Copa Airlines flights
AviancaPriceFrom $448Free CancellationRating
6.5
2,549 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
11,995 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $494Free CancellationRating
7.4
1,988 reviews
Search LATAM Airlines flights
DeltaPriceFrom $559Free CancellationRating
7.8
8,529 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
10,123 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Bodega Bay
Fremont
Hayward
Berkeley
Walnut Creek
Santa Clara
Sunnyvale
Vallejo
Roseville
Salinas
Sonoma
Daly City
Milpitas
Marina
Palo Alto
Burlingame

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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