What airlines fly to San Francisco?

LATAM Airlines, American Airlines and Copa Airlines are the top three most popular airlines that fly to San Francisco from Santiago according to our data. LATAM Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Santiago Arturo Merino Benitez to San Francisco?

LATAM Airlines and Copa Airlines are the most popular carriers operating from Santiago Arturo Merino Benitez to San Francisco

Which airport is the most popular layover for flights between Santiago and San Francisco?

Houston (IAH) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Santiago to San Francisco?

Flights via Houston (IAH) offer the lowest average round-trip price of $710.

Which layover airport has the shortest travel time from Santiago to San Francisco?

Flights connecting via Los Angeles (LAX) have the shortest average one-way travel time: 14h 24m.

Which layover airport has the shortest connection time from Santiago to San Francisco?

Houston (IAH) has the shortest average layover time for this route: 2h 03m.

When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

There are 6 operators available for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport as of September 2026.

How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$383 Cheap Flights from Santiago to San Francisco in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Round-trip

One-way

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Cheap round-trip flights

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8:40 pm - 2:46 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

22h 06m1 stop Atlanta Hartsfield-Jackson

6:00 am - 8:15 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

22h 15m1 stop Atlanta Hartsfield-Jackson

$645JetBlue

Thu, Sep 24 - Thu, Oct 1

8:40 pm - 2:46 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

22h 06m1 stop Atlanta Hartsfield-Jackson

6:00 am - 8:15 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

22h 15m1 stop Atlanta Hartsfield-Jackson

$695JetBlue

Thu, Sep 24 - Thu, Oct 1

7:30 am - 10:55 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

20h 25m2 stops Bogotá El Dorado San Salvador El Salvador Intl

11:00 pm - 1:05 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

21h 05m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$714Avianca

Thu, Feb 18 - Thu, Mar 4

7:30 am - 9:40 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl

11:00 pm - 1:05 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

21h 05m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$714Avianca

Mon, Feb 8 - Mon, Feb 22

7:30 am - 9:23 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 53m2 stops Lima J Chavez Intl Los Angeles

7:05 am - 5:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

17h 30m1 stop Los Angeles

$728LATAM Airlines

Fri, Nov 20 - Fri, Nov 27

11:55 pm - 1:52 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 57m1 stop Los Angeles

7:05 am - 5:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

17h 30m1 stop Los Angeles

$728LATAM Airlines

Fri, Nov 20 - Fri, Nov 27

5:22 am - 11:40 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

22h 18m1 stop Panama City Tocumen Intl

7:36 pm - 12:19 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

23h 43m1 stop Panama City Tocumen Intl

$763Copa Airlines

Fri, Oct 30 - Thu, Nov 5

3:28 am - 11:40 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

24h 12m1 stop Panama City Tocumen Intl

7:36 pm - 3:38 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

27h 02m1 stop Panama City Tocumen Intl

$763Copa Airlines

Fri, Oct 30 - Wed, Nov 4

9:55 pm - 12:02 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 07m2 stops Lima J Chavez Intl Los Angeles

6:00 am - 6:40 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

19h 40m1 stop Atlanta Hartsfield-Jackson

$766Delta

Tue, Dec 22 - Mon, Jan 4

9:50 pm - 10:46 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

17h 56m1 stop Atlanta Hartsfield-Jackson

6:00 am - 6:40 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

19h 40m1 stop Atlanta Hartsfield-Jackson

$766Delta

Thu, Dec 24 - Mon, Jan 4

Cheap last minute flights

Enter your travel dates to find the best prices.

11:55 pm - 8:08 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

24h 13m1 stop New York John F Kennedy Intl

7:00 am - 7:25 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

20h 25m1 stop New York John F Kennedy Intl

$645JetBlue

Fri, Sep 11 - Mon, Sep 21

11:55 pm - 3:54 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 59m1 stop Los Angeles

11:33 am - 8:15 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

16h 42m1 stop Atlanta Hartsfield-Jackson

$695JetBlue

Fri, Sep 11 - Mon, Sep 21

4:20 pm - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

24h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl

2:15 pm - 3:15 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

21h 00m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$739Avianca

Mon, Sep 14 - Mon, Sep 28

1:30 am - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

39h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl

12:00 am - 1:05 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

21h 05m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$748Avianca

Mon, Sep 14 - Wed, Oct 28

9:30 pm - 3:30 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

22h 00m2 stops Miami Los Angeles

11:39 am - 8:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

16h 56m1 stop Miami

$1,005American Airlines

Tue, Sep 15 - Thu, Oct 29

9:30 pm - 11:59 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

30h 29m1 stop Miami

11:39 am - 8:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

16h 56m1 stop Miami

$1,071American Airlines

Tue, Sep 15 - Thu, Oct 29

5:14 am - 12:27 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

23h 13m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

4:40 pm - 8:50 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

35h 10m1 stop Houston George Bush Intcntl

$1,177United Airlines

Fri, Sep 11 - Mon, Dec 7

8:55 pm - 12:00 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 05m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

6:00 am - 5:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

18h 35m2 stops Detroit Metropolitan Wayne County Miami

$1,211Delta

Tue, Sep 15 - Wed, Nov 11

8:40 pm - 10:21 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

17h 41m1 stop Atlanta Hartsfield-Jackson

6:00 am - 7:40 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

20h 40m1 stop Atlanta Hartsfield-Jackson

$1,211Delta

Tue, Sep 15 - Wed, Nov 11

3:14 am - 9:15 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

22h 01m2 stops Panama City Tocumen Intl Newark

5:00 am - 8:50 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

22h 50m1 stop Houston George Bush Intcntl

$1,368United Airlines

Thu, Sep 10 - Tue, Dec 8

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JetBlue flights from Santiago to San Francisco

Our best JetBlue deals on Santiago to San Francisco flight tickets

JetBlue

Sep 24

SCL8:40 pmSantiago Arturo Merino Benitez

22h 06m

1 stop

SFO2:46 pmSan Francisco

Oct 1

SFO6:00 amSan Francisco

22h 15m

1 stop

SCL8:15 amSantiago Arturo Merino Benitez

$645

JetBlue

Sep 24

SCL8:40 pmSantiago Arturo Merino Benitez

22h 06m

1 stop

SFO2:46 pmSan Francisco

Oct 1

SFO6:00 amSan Francisco

22h 15m

1 stop

SCL8:15 amSantiago Arturo Merino Benitez

$695

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets

Avianca

Feb 18

SCL7:30 amSantiago Arturo Merino Benitez

19h 10m

2 stops

SFO9:40 pmSan Francisco

Mar 4

SFO1:15 pmSan Francisco

20h 55m

2 stops

SCL3:10 pmSantiago Arturo Merino Benitez

$714

Avianca

Jan 29

SCL7:30 amSantiago Arturo Merino Benitez

19h 10m

2 stops

SFO9:40 pmSan Francisco

Feb 19

SFO1:15 pmSan Francisco

20h 55m

2 stops

SCL3:10 pmSantiago Arturo Merino Benitez

$715

Avianca

Jan 29

SCL7:30 amSantiago Arturo Merino Benitez

19h 10m

2 stops

SFO9:40 pmSan Francisco

Feb 19

SFO1:15 pmSan Francisco

20h 55m

2 stops

SCL3:10 pmSantiago Arturo Merino Benitez

$716

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 9/24

8:40 pm-2:46 pm

1 stop22h 06m

San Francisco

Thu 10/1

6:00 am-8:15 am

1 stop22h 15m

$645

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 9/24

8:40 pm-2:46 pm

1 stop22h 06m

San Francisco

Thu 10/1

6:00 am-8:15 am

1 stop22h 15m

$695

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

7:30 am-10:55 pm

2 stops20h 25m

San Francisco

Thu 3/4

11:00 pm-1:05 am

2 stops21h 05m

$714

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 2/8

7:30 am-9:40 pm

2 stops19h 10m

San Francisco

Mon 2/22

11:00 pm-1:05 am

2 stops21h 05m

$714

Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 11/20

7:30 am-9:23 pm

2 stops18h 53m

San Francisco

Fri 11/27

7:05 am-5:35 am

1 stop17h 30m

$728

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 11/20

11:55 pm-1:52 pm

1 stop18h 57m

San Francisco

Fri 11/27

7:05 am-5:35 am

1 stop17h 30m

$728

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/30

5:22 am-11:40 pm

1 stop22h 18m

San Francisco

Thu 11/5

7:36 pm-12:19 am

1 stop23h 43m

$763

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/30

3:28 am-11:40 pm

1 stop24h 12m

San Francisco

Wed 11/4

7:36 pm-3:38 am

1 stop27h 02m

$763

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 12/22

9:55 pm-12:02 pm

2 stops19h 07m

San Francisco

Mon 1/4

6:00 am-6:40 am

1 stop19h 40m

$766

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/24

9:50 pm-10:46 am

1 stop17h 56m

San Francisco

Mon 1/4

6:00 am-6:40 am

1 stop19h 40m

$766

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $666 to $936.
The lowest price recently found on this route was $645.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $616.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $681 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $639 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 29% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of September 2026, prices for Santiago to San Francisco flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found	$383
Fastest flight time	15h 54m
Direct flights	None

The best one-way flight to San Francisco from Santiago in the past 72 hours is $383. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $645.

The fastest flight from Santiago to San Francisco takes 15h 54m

There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.

Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

How far is Santiago Arturo Merino Benitez to San Francisco by plane?
A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 15h 54m is a normal flight duration for this route.
When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.
How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
There are 6 operators available for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport as of September 2026.
How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Santiago to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Santiago to San Francisco is LATAM Airlines, representing 34% of all bookings. The subsequent popular airlines are American Airlines at 18%, Copa Airlines at 16%, and Delta at 15%.

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $311	Free Cancellation	Rating 7.6 1,544 reviews	Search Copa Airlines flights
Avianca	PriceFrom $448	Free Cancellation	Rating 6.5 2,553 reviews	Search Avianca flights
American Airlines	PriceFrom $481	Free Cancellation	Rating 7.1 12,046 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $494	Free Cancellation	Rating 7.4 1,987 reviews	Search LATAM Airlines flights
Delta	PriceFrom $559	Free Cancellation	Rating 7.8 8,553 reviews	Search Delta flights
United Airlines	PriceFrom $571	Free Cancellation	Rating 7.4 10,190 reviews	Search United Airlines flights

Santa Cruz

Carmel-by-the-Sea

Modesto

South San Francisco

Bodega Bay

Hayward

Fremont

Berkeley

Walnut Creek

Santa Clara

Sunnyvale

Vallejo

Salinas

Roseville

Half Moon Bay

Sonoma

Daly City

Milpitas

Marina

Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Santiago to San Francisco from $383

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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JetBlue flights from Santiago to San Francisco

Our best JetBlue deals on Santiago to San Francisco flight tickets

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets

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How to get the cheapest flight ticket from Santiago to San Francisco

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

How far in advance should I book a flight from Santiago to San Francisco?

Can stopping save me money on Santiago to San Francisco flights?

How have Santiago to San Francisco flight prices changed over time?

What is the cheapest airline that flies from Santiago Arturo Merino Benitez to San Francisco?

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Santiago and San Francisco?

Which layover airport offers the lowest fares from Santiago to San Francisco?

Which layover airport has the shortest travel time from Santiago to San Francisco?

Which layover airport has the shortest connection time from Santiago to San Francisco?

When to book flights from Santiago to San Francisco

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Santiago to San Francisco

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo

Traveling to a place near San Francisco?

Why use momondo?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Francisco

List of cabin classes available on flights landing in San Francisco. Availability may vary depending on flight origin and airline.

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