Which layover airport offers the lowest fares from Santiago to San Francisco?

Flights via Houston (IAH) offer the lowest average round-trip price of $710.

Which airport is the most popular layover for flights between Santiago and San Francisco?

Houston (IAH) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to San Francisco?

LATAM Airlines, American Airlines and Copa Airlines are the top three most popular airlines that fly to San Francisco from Santiago according to our data. LATAM Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Santiago Arturo Merino Benitez to San Francisco?

Avianca is the most popular carrier operating from Santiago Arturo Merino Benitez to San Francisco

Which layover airport has the shortest travel time from Santiago to San Francisco?

Flights connecting via Los Angeles (LAX) have the shortest average one-way travel time: 14h 24m.

Which layover airport has the shortest connection time from Santiago to San Francisco?

Houston (IAH) has the shortest average layover time for this route: 2h 03m.

When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

There are 6 operators available for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport as of September 2026.

How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$384 Cheap Flights from Santiago to San Francisco in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

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One-way

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Cheap round-trip flights

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9:55 pm - 11:04 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 09m2 stops Lima J Chavez Intl Los Angeles

7:00 am - 5:20 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

17h 20m2 stops Los Angeles Lima J Chavez Intl

$581LATAM Airlines

Thu, Feb 18 - Thu, Mar 4

11:55 pm - 11:04 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

16h 09m1 stop Los Angeles

7:00 am - 5:20 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

17h 20m2 stops Los Angeles Lima J Chavez Intl

$581LATAM Airlines

Thu, Feb 18 - Thu, Mar 4

5:07 am - 12:12 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

23h 05m1 stop Panama City Tocumen Intl

7:36 pm - 11:36 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

23h 00m1 stop Panama City Tocumen Intl

$593Copa Airlines

Sun, Nov 1 - Sun, Nov 8

12:23 pm - 11:40 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

15h 17m1 stop Panama City Tocumen Intl

7:36 pm - 3:43 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

27h 07m1 stop Panama City Tocumen Intl

$593Copa Airlines

Thu, Oct 1 - Wed, Dec 2

11:10 pm - 12:45 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 35m1 stop Atlanta Hartsfield-Jackson

6:00 am - 6:40 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

19h 40m1 stop Atlanta Hartsfield-Jackson

$596Delta

Mon, Feb 15 - Sun, Feb 28

10:45 pm - 5:10 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

23h 25m1 stop Houston George Bush Intcntl

7:15 am - 8:50 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

20h 35m1 stop Houston George Bush Intcntl

$605United Airlines

Thu, Nov 5 - Mon, Nov 9

10:15 pm - 7:39 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

26h 24m1 stop Miami

11:12 am - 7:45 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

15h 33m1 stop Dallas/Fort Worth

$698American Airlines

Tue, Jan 19 - Sun, Jan 31

10:15 pm - 1:07 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 52m2 stops Miami Dallas/Fort Worth

10:33 am - 7:45 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

16h 12m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth

$702American Airlines

Tue, Jan 19 - Sun, Jan 31

11:55 pm - 5:02 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

21h 07m2 stops Miami Atlanta Hartsfield-Jackson

7:00 am - 7:25 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

20h 25m1 stop New York John F Kennedy Intl

$762Delta

Tue, Oct 13 - Tue, Oct 20

10:45 pm - 7:20 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

37h 35m1 stop Houston George Bush Intcntl

12:45 am - 8:50 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

27h 05m1 stop Houston George Bush Intcntl

$770United Airlines

Wed, Jan 20 - Mon, Feb 8

Cheap last minute flights

Enter your travel dates to find the best prices.

4:20 pm - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

24h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl

11:55 pm - 12:20 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

20h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$781Avianca

Mon, Sep 21 - Thu, Oct 22

4:20 pm - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

24h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl

2:30 am - 5:45 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

23h 15m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$787Avianca

Mon, Sep 21 - Sat, Sep 26

4:20 pm - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

24h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl

2:30 am - 5:45 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

23h 15m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$798Avianca

Mon, Sep 21 - Sat, Sep 26

1:30 am - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

39h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl

10:21 am - 5:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

15h 14m1 stop Los Angeles

$1,031Multiple Airlines

Sun, Sep 20 - Thu, Oct 22

7:40 am - 12:50 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

57h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl

10:21 am - 5:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

15h 14m1 stop Los Angeles

$1,048Multiple Airlines

Sun, Sep 20 - Thu, Oct 22

4:20 pm - 10:35 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

34h 15m2 stops Bogotá El Dorado San Salvador El Salvador Intl

1:00 pm - 11:55 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

30h 55m3 stops Calgary Toronto Pearson Intl Punta Cana

$1,069Multiple Airlines

Mon, Sep 21 - Thu, Oct 22

9:30 pm - 11:59 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

30h 29m1 stop Miami

8:33 am - 8:10 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

19h 37m1 stop Miami

$1,088American Airlines

Mon, Sep 21 - Thu, Oct 22

9:30 pm - 12:05 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 35m1 stop Miami

11:27 am - 8:00 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

16h 33m1 stop Miami

$1,143American Airlines

Mon, Sep 21 - Sun, Sep 27

8:40 pm - 12:00 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 20m1 stop Atlanta Hartsfield-Jackson

6:00 am - 7:00 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

21h 00m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

$1,231Delta

Mon, Sep 21 - Sun, Sep 27

9:30 am - 12:00 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

30h 30m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson

6:00 am - 6:25 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

32h 25m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

$1,385LATAM Airlines

Mon, Sep 21 - Sun, Sep 27

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Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets

Avianca

Sep 22

SCL7:40 amSantiago Arturo Merino Benitez

20h 15m

2 stops

SFO11:55 pmSan Francisco

Oct 4

SFO11:55 pmSan Francisco

20h 25m

2 stops

SCL12:20 amSantiago Arturo Merino Benitez

$758

Avianca

Oct 10

SCL7:40 amSantiago Arturo Merino Benitez

20h 15m

2 stops

SFO11:55 pmSan Francisco

Oct 17

SFO11:55 pmSan Francisco

20h 25m

2 stops

SCL12:20 amSantiago Arturo Merino Benitez

$764

Avianca

Sep 30

SCL7:40 amSantiago Arturo Merino Benitez

18h 55m

2 stops

SFO10:35 pmSan Francisco

Oct 7

SFO2:15 pmSan Francisco

21h 00m

2 stops

SCL3:15 pmSantiago Arturo Merino Benitez

$768

American Airlines flights from Santiago to San Francisco

Our best American Airlines deals on Santiago to San Francisco flight tickets

American Airlines

Dec 17

SCL11:45 pmSantiago Arturo Merino Benitez

28h 08m

1 stop

SFO10:53 pmSan Francisco

Jan 5

SFO7:54 amSan Francisco

18h 51m

1 stop

SCL7:45 amSantiago Arturo Merino Benitez

$615

American Airlines

Dec 17

SCL11:45 pmSantiago Arturo Merino Benitez

28h 08m

1 stop

SFO10:53 pmSan Francisco

Jan 5

SFO8:21 amSan Francisco

19h 39m

2 stops

SCL9:00 amSantiago Arturo Merino Benitez

$619

American Airlines

Jan 19

SCL10:15 pmSantiago Arturo Merino Benitez

26h 24m

1 stop

SFO7:39 pmSan Francisco

Jan 31

SFO11:12 amSan Francisco

15h 33m

1 stop

SCL7:45 amSantiago Arturo Merino Benitez

$698

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

9:55 pm-11:04 am

2 stops18h 09m

San Francisco

Thu 3/4

7:00 am-5:20 am

2 stops17h 20m

$581

Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

11:55 pm-11:04 am

1 stop16h 09m

San Francisco

Thu 3/4

7:00 am-5:20 am

2 stops17h 20m

$581

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Sun 11/1

5:07 am-12:12 am

1 stop23h 05m

San Francisco

Sun 11/8

7:36 pm-11:36 pm

1 stop23h 00m

$593

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 10/1

12:23 pm-11:40 pm

1 stop15h 17m

San Francisco

Wed 12/2

7:36 pm-3:43 am

1 stop27h 07m

$593

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 2/15

11:10 pm-12:45 pm

1 stop18h 35m

San Francisco

Sun 2/28

6:00 am-6:40 am

1 stop19h 40m

$596

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 11/5

10:45 pm-5:10 pm

1 stop23h 25m

San Francisco

Mon 11/9

7:15 am-8:50 am

1 stop20h 35m

$605

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 1/19

10:15 pm-7:39 pm

1 stop26h 24m

San Francisco

Sun 1/31

11:12 am-7:45 am

1 stop15h 33m

$698

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 1/19

10:15 pm-1:07 pm

2 stops19h 52m

San Francisco

Sun 1/31

10:33 am-7:45 am

2 stops16h 12m

$702

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/13

11:55 pm-5:02 pm

2 stops21h 07m

San Francisco

Tue 10/20

7:00 am-7:25 am

1 stop20h 25m

$762

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 1/20

10:45 pm-7:20 am

1 stop37h 35m

San Francisco

Mon 2/8

12:45 am-8:50 am

1 stop27h 05m

$770

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $667 to $945.
The lowest price recently found on this route was $581.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $616.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $682 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $638 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 29% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of September 2026, prices for Santiago to San Francisco flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found	$384
Fastest flight time	15h 17m
Direct flights	None

The best one-way flight to San Francisco from Santiago in the past 72 hours is $384. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $581.

The fastest flight from Santiago to San Francisco takes 15h 17m

There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.

Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

How far is Santiago Arturo Merino Benitez to San Francisco by plane?
A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 15h 17m is a normal flight duration for this route.
When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.
How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
There are 6 operators available for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport as of September 2026.
How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Santiago to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Santiago to San Francisco is LATAM Airlines, representing 31% of all bookings. The subsequent popular airlines are American Airlines at 19%, Copa Airlines at 16%, and Delta at 16%.

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $311	Free Cancellation	Rating 7.6 1,542 reviews	Search Copa Airlines flights
Avianca	PriceFrom $448	Free Cancellation	Rating 6.5 2,551 reviews	Search Avianca flights
American Airlines	PriceFrom $481	Free Cancellation	Rating 7.1 12,054 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $494	Free Cancellation	Rating 7.4 1,985 reviews	Search LATAM Airlines flights
Delta	PriceFrom $531	Free Cancellation	Rating 7.8 8,568 reviews	Search Delta flights
United Airlines	PriceFrom $571	Free Cancellation	Rating 7.4 10,214 reviews	Search United Airlines flights

Santa Cruz

Carmel-by-the-Sea

Modesto

South San Francisco

Bodega Bay

Hayward

Berkeley

Fremont

Santa Clara

Walnut Creek

Sunnyvale

Vallejo

Half Moon Bay

Roseville

Salinas

Sonoma

Daly City

Milpitas

Pacific Grove

Marina

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Santiago to San Francisco from $384

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 10/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets

American Airlines flights from Santiago to San Francisco

Our best American Airlines deals on Santiago to San Francisco flight tickets

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How to get the cheapest flight ticket from Santiago to San Francisco

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

How far in advance should I book a flight from Santiago to San Francisco?

Can stopping save me money on Santiago to San Francisco flights?

How have Santiago to San Francisco flight prices changed over time?

What is the cheapest airline that flies from Santiago Arturo Merino Benitez to San Francisco?

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Santiago and San Francisco?

Which layover airport offers the lowest fares from Santiago to San Francisco?

Which layover airport has the shortest travel time from Santiago to San Francisco?

Which layover airport has the shortest connection time from Santiago to San Francisco?

When to book flights from Santiago to San Francisco

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Santiago to San Francisco

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo

Traveling to a place near San Francisco?

Why use momondo?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Francisco

List of cabin classes available on flights landing in San Francisco. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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