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Cheap flights from Santiago to San Francisco from $276

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
11:55 pm - 11:20 pm
SFO
-
SCL
20h 25m
2 stops
$542Avianca
Thu, Aug 13 - Tue, Aug 18
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
11:55 pm - 11:20 pm
SFO
-
SCL
20h 25m
2 stops
$544Avianca
Tue, Aug 18 - Tue, Aug 25
LATAM Airlines Logo
11:25 pm - 1:45 pm
SCL
-
SFO
19h 20m
1 stop
LATAM Airlines Logo
7:30 am - 4:30 pm
SFO
-
SCL
28h 00m
2 stops
$547LATAM Airlines
Thu, Nov 5 - Thu, Nov 26
LATAM Airlines Logo
8:40 pm - 7:39 pm
SCL
-
SFO
25h 59m
1 stop
LATAM Airlines Logo
6:00 am - 3:00 pm
SFO
-
SCL
29h 00m
2 stops
$549LATAM Airlines
Thu, Aug 27 - Wed, Sep 23
LATAM Airlines Logo
4:30 pm - 11:58 pm
SCL
-
SFO
34h 28m
2 stops
LATAM Airlines Logo
8:00 am - 7:15 am
SFO
-
SCL
20h 15m
1 stop
$550LATAM Airlines
Wed, Aug 12 - Tue, Aug 18
American Airlines Logo
10:15 pm - 5:21 pm
SCL
-
SFO
24h 06m
2 stops
American Airlines Logo
8:00 am - 9:00 am
SFO
-
SCL
20h 00m
2 stops
$552American Airlines
Thu, Nov 5 - Thu, Nov 26
LATAM Airlines Logo
11:00 pm - 11:58 pm
SCL
-
SFO
27h 58m
2 stops
LATAM Airlines Logo
8:00 am - 7:15 am
SFO
-
SCL
20h 15m
1 stop
$554LATAM Airlines
Wed, Aug 5 - Tue, Aug 11
LATAM Airlines Logo
12:40 am - 11:57 pm
SCL
-
SFO
27h 17m
2 stops
LATAM Airlines Logo
6:00 am - 6:55 am
SFO
-
SCL
20h 55m
2 stops
$555LATAM Airlines
Wed, Sep 23 - Thu, Oct 1
LATAM Airlines Logo
11:00 pm - 11:58 pm
SCL
-
SFO
27h 58m
2 stops
LATAM Airlines Logo
11:15 pm - 6:55 am
SFO
-
SCL
28h 40m
2 stops
$557LATAM Airlines
Wed, Aug 5 - Tue, Aug 11
Copa Airlines Logo
2:56 am - 5:59 pm
SCL
-
SFO
18h 03m
1 stop
Copa Airlines Logo
8:21 pm - 10:43 pm
SFO
-
SCL
23h 22m
1 stop
$561Copa Airlines
Wed, Jul 29 - Thu, Aug 13

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Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Aug 13
SCL6:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Aug 18
SFO11:55 pmSan Francisco
20h 25m
2 stops
SCL11:20 pmSantiago Arturo Merino Benitez
$542
Avianca
Aug 18
SCL6:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Aug 25
SFO11:55 pmSan Francisco
20h 25m
2 stops
SCL11:20 pmSantiago Arturo Merino Benitez
$544
Avianca
Aug 5
SCL3:20 pmSantiago Arturo Merino Benitez
35h 35m
2 stops
SFO11:55 pmSan Francisco
Aug 10
SFO7:45 amSan Francisco
36h 35m
3 stops
SCL11:20 pmSantiago Arturo Merino Benitez
$571

LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Nov 5
SCL11:25 pmSantiago Arturo Merino Benitez
19h 20m
1 stop
SFO1:45 pmSan Francisco
Nov 26
SFO7:30 amSan Francisco
28h 00m
2 stops
SCL4:30 pmSantiago Arturo Merino Benitez
$547
LATAM Airlines
Aug 27
SCL8:40 pmSantiago Arturo Merino Benitez
25h 59m
1 stop
SFO7:39 pmSan Francisco
Sep 23
SFO6:00 amSan Francisco
29h 00m
2 stops
SCL3:00 pmSantiago Arturo Merino Benitez
$549
LATAM Airlines
Aug 12
SCL4:30 pmSantiago Arturo Merino Benitez
34h 28m
2 stops
SFO11:58 pmSan Francisco
Aug 18
SFO8:00 amSan Francisco
20h 15m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$550

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/13

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Tue 8/18

11:55 pm-11:20 pm

2 stops20h 25m

$542

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/18

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Tue 8/25

11:55 pm-11:20 pm

2 stops20h 25m

$544

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 11/5

11:25 pm-1:45 pm

1 stop19h 20m

San Francisco

Thu 11/26

7:30 am-4:30 pm

2 stops28h 00m

$547

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/27

8:40 pm-7:39 pm

1 stop25h 59m

San Francisco

Wed 9/23

6:00 am-3:00 pm

2 stops29h 00m

$549

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/12

4:30 pm-11:58 pm

2 stops34h 28m

San Francisco

Tue 8/18

8:00 am-7:15 am

1 stop20h 15m

$550

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 11/5

10:15 pm-5:21 pm

2 stops24h 06m

San Francisco

Thu 11/26

8:00 am-9:00 am

2 stops20h 00m

$552

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/5

11:00 pm-11:58 pm

2 stops27h 58m

San Francisco

Tue 8/11

8:00 am-7:15 am

1 stop20h 15m

$554

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 9/23

12:40 am-11:57 pm

2 stops27h 17m

San Francisco

Thu 10/1

6:00 am-6:55 am

2 stops20h 55m

$555

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/5

11:00 pm-11:58 pm

2 stops27h 58m

San Francisco

Tue 8/11

11:15 pm-6:55 am

2 stops28h 40m

$557

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 7/29

2:56 am-5:59 pm

1 stop18h 03m

San Francisco

Thu 8/13

8:21 pm-10:43 pm

1 stop23h 22m

$561

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $557.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $647 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $568 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 41% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of July 2026, prices for Santiago to San Francisco flights are approximately 5% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Fastest flight time

17h 06m

Direct flights

None
The fastest flight from Santiago to San Francisco takes 17h 06m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 17h 06m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,563 reviews
Search Copa Airlines flights
AviancaPriceFrom $408Free CancellationRating
6.5
2,524 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
11,808 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $501Free CancellationRating
7.4
1,953 reviews
Search LATAM Airlines flights
DeltaPriceFrom $509Free CancellationRating
7.8
8,457 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
9,977 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Hayward
Bodega Bay
Fremont
Sonoma
Roseville
Walnut Creek
Santa Clara
Berkeley
Salinas
Vallejo
Sunnyvale
Burlingame
Daly City
Big Sur
Milpitas
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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