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Cheap flights from Santiago to San Francisco from $278

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
11:55 pm - 11:20 pm
SFO
-
SCL
20h 25m
2 stops
$544Avianca
Tue, Aug 18 - Tue, Aug 25
Avianca Logo
6:40 am - 11:55 pm
SCL
-
SFO
20h 15m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$547Avianca
Thu, Aug 20 - Mon, Aug 31
Avianca Logo
6:40 am - 11:55 pm
SCL
-
SFO
20h 15m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$549Avianca
Thu, Aug 20 - Mon, Aug 31
Avianca Logo
3:20 pm - 10:35 pm
SCL
-
SFO
34h 15m
2 stops
Avianca Logo
7:45 am - 2:15 pm
SFO
-
SCL
27h 30m
3 stops
$574Avianca
Wed, Aug 5 - Mon, Aug 10
Avianca Logo
7:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
11:55 pm - 5:45 am
SFO
-
SCL
25h 50m
2 stops
$575Avianca
Thu, Sep 24 - Thu, Oct 1
Avianca Logo
6:40 am - 12:50 pm
SCL
-
SFO
33h 10m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$576Avianca
Wed, Aug 19 - Sun, Aug 30
Avianca Logo
3:20 pm - 10:35 pm
SCL
-
SFO
34h 15m
2 stops
Avianca Logo
7:45 am - 2:15 pm
SFO
-
SCL
27h 30m
3 stops
$578Avianca
Wed, Aug 12 - Tue, Aug 18
Avianca Logo
6:40 am - 11:55 pm
SCL
-
SFO
20h 15m
2 stops
Avianca Logo
2:30 am - 5:45 am
SFO
-
SCL
23h 15m
2 stops
$581Avianca
Thu, Sep 3 - Tue, Sep 15
Avianca Logo
12:30 am - 10:35 pm
SCL
-
SFO
25h 05m
2 stops
Avianca Logo
2:30 am - 5:45 am
SFO
-
SCL
23h 15m
2 stops
$583Avianca
Wed, Sep 2 - Tue, Sep 15
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
2:15 pm - 4:45 am
SFO
-
SCL
35h 30m
2 stops
$585Avianca
Tue, Aug 25 - Sun, Aug 30

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Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Aug 18
SCL6:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Aug 25
SFO11:55 pmSan Francisco
20h 25m
2 stops
SCL11:20 pmSantiago Arturo Merino Benitez
$544
Avianca
Aug 20
SCL6:40 amSantiago Arturo Merino Benitez
20h 15m
2 stops
SFO11:55 pmSan Francisco
Aug 31
SFO2:15 pmSan Francisco
21h 00m
2 stops
SCL2:15 pmSantiago Arturo Merino Benitez
$547
Avianca
Aug 20
SCL6:40 amSantiago Arturo Merino Benitez
20h 15m
2 stops
SFO11:55 pmSan Francisco
Aug 31
SFO2:15 pmSan Francisco
21h 00m
2 stops
SCL2:15 pmSantiago Arturo Merino Benitez
$549

LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Sep 19
SCL5:40 amSantiago Arturo Merino Benitez
20h 27m
2 stops
SFO10:07 pmSan Francisco
Nov 15
SFO7:30 amSan Francisco
19h 10m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$625
LATAM Airlines
Dec 11
SCL7:30 amSantiago Arturo Merino Benitez
20h 41m
2 stops
SFO11:11 pmSan Francisco
Mar 29
SFO6:00 amSan Francisco
25h 04m
3 stops
SCL11:04 amSantiago Arturo Merino Benitez
$631
LATAM Airlines
Jul 30
SCL11:05 pmSantiago Arturo Merino Benitez
37h 55m
2 stops
SFO10:00 amSan Francisco
Aug 13
SFO9:30 amSan Francisco
17h 05m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$840

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 16, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/18

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Tue 8/25

11:55 pm-11:20 pm

2 stops20h 25m

$544

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/20

6:40 am-11:55 pm

2 stops20h 15m

San Francisco

Mon 8/31

2:15 pm-2:15 pm

2 stops21h 00m

$547

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/20

6:40 am-11:55 pm

2 stops20h 15m

San Francisco

Mon 8/31

2:15 pm-2:15 pm

2 stops21h 00m

$549

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/5

3:20 pm-10:35 pm

2 stops34h 15m

San Francisco

Mon 8/10

7:45 am-2:15 pm

3 stops27h 30m

$574

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 9/24

7:40 am-10:35 pm

2 stops18h 55m

San Francisco

Thu 10/1

11:55 pm-5:45 am

2 stops25h 50m

$575

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/19

6:40 am-12:50 pm

2 stops33h 10m

San Francisco

Sun 8/30

2:15 pm-2:15 pm

2 stops21h 00m

$576

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/12

3:20 pm-10:35 pm

2 stops34h 15m

San Francisco

Tue 8/18

7:45 am-2:15 pm

3 stops27h 30m

$578

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 9/3

6:40 am-11:55 pm

2 stops20h 15m

San Francisco

Tue 9/15

2:30 am-5:45 am

2 stops23h 15m

$581

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 9/2

12:30 am-10:35 pm

2 stops25h 05m

San Francisco

Tue 9/15

2:30 am-5:45 am

2 stops23h 15m

$583

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/25

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Sun 8/30

2:15 pm-4:45 am

2 stops35h 30m

$585

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $560.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $647 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $568 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 41% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of July 2026, prices for Santiago to San Francisco flights are approximately 5% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Fastest flight time

17h 06m

Direct flights

None
The fastest flight from Santiago to San Francisco takes 17h 06m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 17h 06m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
AviancaPriceFrom $408Free CancellationRating
6.5
2,523 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
11,811 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $501Free CancellationRating
7.4
1,956 reviews
Search LATAM Airlines flights
DeltaPriceFrom $509Free CancellationRating
7.8
8,471 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
9,993 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Hayward
Fremont
Sonoma
Bodega Bay
Walnut Creek
Roseville
Santa Clara
Berkeley
Vallejo
Salinas
Sunnyvale
Burlingame
Daly City
Big Sur
Milpitas
Palo Alto

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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