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Cheap flights from Santiago to San Francisco from $277

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 8/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$546Avianca
Fri, Jul 24 - Mon, Jul 27
Avianca Logo
4:20 pm - 10:35 pm
SCL
-
SFO
34h 15m
2 stops
Avianca Logo
11:55 pm - 5:45 am
SFO
-
SCL
25h 50m
2 stops
$559Avianca
Mon, Sep 7 - Thu, Sep 10
Copa Airlines Logo
11:22 am - 6:00 pm
SCL
-
SFO
33h 38m
1 stop
Copa Airlines Logo
1:12 am - 1:50 am
SFO
-
SCL
21h 38m
1 stop
$561Copa Airlines
Thu, Jul 23 - Tue, Aug 4
Delta Logo
11:00 pm - 10:00 pm
SCL
-
SFO
26h 00m
2 stops
Delta Logo
9:30 am - 5:35 am
SFO
-
SCL
17h 05m
1 stop
$563Delta
Mon, Aug 10 - Mon, Aug 24
Copa Airlines Logo
2:14 am - 11:40 pm
SCL
-
SFO
24h 26m
1 stop
Copa Airlines Logo
8:21 pm - 11:26 pm
SFO
-
SCL
24h 05m
1 stop
$568Copa Airlines
Mon, Aug 17 - Tue, Aug 25
Delta Logo
8:40 pm - 5:31 pm
SCL
-
SFO
23h 51m
1 stop
Delta Logo
7:13 am - 6:55 am
SFO
-
SCL
20h 42m
2 stops
$571Delta
Thu, Jul 30 - Thu, Aug 13
Avianca Logo
3:20 pm - 12:50 pm
SCL
-
SFO
24h 30m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$572Avianca
Mon, Jul 27 - Wed, Aug 12
Avianca Logo
3:20 pm - 12:50 pm
SCL
-
SFO
24h 30m
2 stops
Avianca Logo
2:30 am - 4:45 am
SFO
-
SCL
23h 15m
2 stops
$573Avianca
Thu, Jul 23 - Tue, Aug 4
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
7:45 am - 11:20 pm
SFO
-
SCL
36h 35m
3 stops
$575Avianca
Tue, Aug 18 - Tue, Aug 25
Delta Logo
11:25 pm - 11:54 am
SCL
-
SFO
16h 29m
1 stop
Delta Logo
11:45 pm - 5:35 am
SFO
-
SCL
25h 50m
2 stops
$576Delta
Wed, Oct 14 - Mon, Oct 26

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United Airlines flights from Santiago to San Francisco

Our best United Airlines deals on Santiago to San Francisco flight tickets
United Airlines
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
18h 33m
1 stop
SFO12:18 pmSan Francisco
Nov 15
SFO7:00 amSan Francisco
20h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
$580
United Airlines
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
15h 50m
1 stop
SFO9:35 amSan Francisco
Nov 15
SFO11:59 pmSan Francisco
27h 51m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
$600
United Airlines
Jul 3
SCL4:21 amSantiago Arturo Merino Benitez
22h 44m
2 stops
SFO12:05 amSan Francisco
Jul 15
SFO12:45 amSan Francisco
22h 05m
2 stops
SCL1:50 amSantiago Arturo Merino Benitez
$850

Copa Airlines flights from Santiago to San Francisco

Our best Copa Airlines deals on Santiago to San Francisco flight tickets
Copa Airlines
Jul 23
SCL11:22 amSantiago Arturo Merino Benitez
33h 38m
1 stop
SFO6:00 pmSan Francisco
Aug 4
SFO1:12 amSan Francisco
21h 38m
1 stop
SCL1:50 amSantiago Arturo Merino Benitez
$561
Copa Airlines
Aug 17
SCL2:14 amSantiago Arturo Merino Benitez
24h 26m
1 stop
SFO11:40 pmSan Francisco
Aug 25
SFO8:21 pmSan Francisco
24h 05m
1 stop
SCL11:26 pmSantiago Arturo Merino Benitez
$568
Copa Airlines
Jul 29
SCL2:56 amSantiago Arturo Merino Benitez
23h 44m
1 stop
SFO11:40 pmSan Francisco
Aug 13
SFO8:21 pmSan Francisco
23h 22m
1 stop
SCL10:43 pmSantiago Arturo Merino Benitez
$591

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 7/24

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Mon 7/27

2:15 pm-2:15 pm

2 stops21h 00m

$546

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 9/7

4:20 pm-10:35 pm

2 stops34h 15m

San Francisco

Thu 9/10

11:55 pm-5:45 am

2 stops25h 50m

$559

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/23

11:22 am-6:00 pm

1 stop33h 38m

San Francisco

Tue 8/4

1:12 am-1:50 am

1 stop21h 38m

$561

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 8/10

11:00 pm-10:00 pm

2 stops26h 00m

San Francisco

Mon 8/24

9:30 am-5:35 am

1 stop17h 05m

$563

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 8/17

2:14 am-11:40 pm

1 stop24h 26m

San Francisco

Tue 8/25

8:21 pm-11:26 pm

1 stop24h 05m

$568

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/30

8:40 pm-5:31 pm

1 stop23h 51m

San Francisco

Thu 8/13

7:13 am-6:55 am

2 stops20h 42m

$571

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 7/27

3:20 pm-12:50 pm

2 stops24h 30m

San Francisco

Wed 8/12

2:15 pm-2:15 pm

2 stops21h 00m

$572

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/23

3:20 pm-12:50 pm

2 stops24h 30m

San Francisco

Tue 8/4

2:30 am-4:45 am

2 stops23h 15m

$573

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/18

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Tue 8/25

7:45 am-11:20 pm

3 stops36h 35m

$575

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 10/14

11:25 pm-11:54 am

1 stop16h 29m

San Francisco

Mon 10/26

11:45 pm-5:35 am

2 stops25h 50m

$576

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $568.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $650 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $593 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 41% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of June 2026, prices for Santiago to San Francisco flights are approximately 66% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Fastest flight time

16h 38m

Direct flights

None
The fastest flight from Santiago to San Francisco takes 16h 38m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 16h 38m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,569 reviews
Search Copa Airlines flights
AviancaPriceFrom $408Free CancellationRating
6.5
2,534 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
11,722 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $501Free CancellationRating
7.4
1,940 reviews
Search LATAM Airlines flights
DeltaPriceFrom $559Free CancellationRating
7.8
8,422 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
9,866 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Hayward
Bodega Bay
Roseville
Fremont
Walnut Creek
Santa Clara
South San Francisco
Berkeley
Vallejo
Sunnyvale
Salinas
Big Sur
Pacific Grove
Daly City
Burlingame
Calistoga

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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