Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santiago to San Francisco from $255

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Avianca Logo
4:25 pm - 10:50 pmSCL-SFO
34h 25m2 stops
Avianca Logo
1:35 am - 5:30 amSFO-SCL
22h 55m2 stops
$458Avianca
Find Deal
Fri, Oct 31 - Sat, Nov 15
Avianca Logo
11:55 pm - 11:55 pmSCL-SFO
27h 00m2 stops
Avianca Logo
2:20 pm - 10:30 pmSFO-SCL
29h 10m2 stops
$468Avianca
Find Deal
Fri, Aug 29 - Fri, Sep 5
Avianca Logo
3:30 pm - 12:35 pmSCL-SFO
25h 05m2 stops
Avianca Logo
2:20 pm - 5:15 amSFO-SCL
34h 55m2 stops
$474Avianca
Find Deal
Sun, Sep 28 - Sat, Oct 4
LATAM Airlines Logo
11:05 pm - 9:58 amSCL-SFO
14h 53m1 stop
LATAM Airlines Logo
6:15 am - 7:00 amSFO-SCL
20h 45m1 stop
$504LATAM Airlines
Find Deal
Mon, Sep 29 - Sun, Oct 5
LATAM Airlines Logo
11:05 pm - 2:48 pmSCL-SFO
19h 43m1 stop
LATAM Airlines Logo
11:58 am - 7:00 amSFO-SCL
15h 02m1 stop
$506LATAM Airlines
Find Deal
Tue, Sep 23 - Tue, Oct 21
Delta Logo
9:40 pm - 10:10 amSCL-SFO
16h 30m1 stop
Delta Logo
6:15 am - 7:00 amSFO-SCL
20h 45m1 stop
$510Delta
Find Deal
Tue, Sep 9 - Sun, Sep 28
Copa Airlines Logo
3:23 am - 11:17 pmSCL-SFO
24h 54m1 stop
Copa Airlines Logo
12:36 am - 8:21 pmSFO-SCL
14h 45m1 stop
$529Copa Airlines
Find Deal
Mon, Nov 3 - Tue, Nov 11
Delta Logo
11:55 pm - 3:09 pmSCL-SFO
20h 14m1 stop
Delta Logo
11:30 am - 7:00 amSFO-SCL
14h 30m1 stop
$533Delta
Find Deal
Tue, Nov 18 - Tue, Jan 27
American Airlines Logo
11:15 pm - 4:01 pmSCL-SFO
21h 46m2 stops
American Airlines Logo
9:50 am - 7:50 amSFO-SCL
17h 00m2 stops
$548American Airlines
Find Deal
Mon, Nov 17 - Tue, Jan 27
Copa Airlines Logo
12:20 pm - 11:17 pmSCL-SFO
15h 57m1 stop
Copa Airlines Logo
12:42 am - 3:17 amSFO-SCL
21h 35m1 stop
$549Copa Airlines
Find Deal
Mon, Nov 17 - Sun, Jan 25

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Oct 31
SCL4:25 pmSantiago Arturo Merino Benitez
34h 25m
2 stops
SFO10:50 pmSan Francisco
Nov 15
SFO1:35 amSan Francisco
22h 55m
2 stops
SCL5:30 amSantiago Arturo Merino Benitez
$458
Find similar
Avianca
Aug 29
SCL11:55 pmSantiago Arturo Merino Benitez
27h 00m
2 stops
SFO11:55 pmSan Francisco
Sep 5
SFO2:20 pmSan Francisco
29h 10m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
$468
Find similar
Avianca
Sep 28
SCL3:30 pmSantiago Arturo Merino Benitez
25h 05m
2 stops
SFO12:35 pmSan Francisco
Oct 4
SFO2:20 pmSan Francisco
34h 55m
2 stops
SCL5:15 amSantiago Arturo Merino Benitez
$474
Find similar

LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Sep 29
SCL11:05 pmSantiago Arturo Merino Benitez
14h 53m
1 stop
SFO9:58 amSan Francisco
Oct 5
SFO6:15 amSan Francisco
20h 45m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$504
Find similar
LATAM Airlines
Sep 23
SCL11:05 pmSantiago Arturo Merino Benitez
19h 43m
1 stop
SFO2:48 pmSan Francisco
Oct 21
SFO11:58 amSan Francisco
15h 02m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$506
Find similar
LATAM Airlines
Oct 13
SCL9:40 pmSantiago Arturo Merino Benitez
16h 18m
1 stop
SFO9:58 amSan Francisco
Oct 22
SFO7:15 amSan Francisco
19h 10m
2 stops
SCL6:25 amSantiago Arturo Merino Benitez
$514
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/31

4:25 pm-10:50 pm

2 stops34h 25m

San Francisco

Sat 11/15

1:35 am-5:30 am

2 stops22h 55m

$458

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 8/29

11:55 pm-11:55 pm

2 stops27h 00m

San Francisco

Fri 9/5

2:20 pm-10:30 pm

2 stops29h 10m

$468

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sun 9/28

3:30 pm-12:35 pm

2 stops25h 05m

San Francisco

Sat 10/4

2:20 pm-5:15 am

2 stops34h 55m

$474

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 9/29

11:05 pm-9:58 am

1 stop14h 53m

San Francisco

Sun 10/5

6:15 am-7:00 am

1 stop20h 45m

$504

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 9/23

11:05 pm-2:48 pm

1 stop19h 43m

San Francisco

Tue 10/21

11:58 am-7:00 am

1 stop15h 02m

$506

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 9/9

9:40 pm-10:10 am

1 stop16h 30m

San Francisco

Sun 9/28

6:15 am-7:00 am

1 stop20h 45m

$510

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/3

3:23 am-11:17 pm

1 stop24h 54m

San Francisco

Tue 11/11

12:36 am-8:21 pm

1 stop14h 45m

$529

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 11/18

11:55 pm-3:09 pm

1 stop20h 14m

San Francisco

Tue 1/27

11:30 am-7:00 am

1 stop14h 30m

$533

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/17

11:15 pm-4:01 pm

2 stops21h 46m

San Francisco

Tue 1/27

9:50 am-7:50 am

2 stops17h 00m

$548

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/17

12:20 pm-11:17 pm

1 stop15h 57m

San Francisco

Sun 1/25

12:42 am-3:17 am

1 stop21h 35m

$549

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $592.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Santiago to San Francisco is on a Saturday when prices can be found for as low as $663. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $834.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Santiago to San Francisco flights are usually those with departure times in the afternoon. Our users have found flights to San Francisco in the afternoon for as low as $565. Flights in the evening are often more expensive with an average ticket price of $822.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $666 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $575 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 37% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of August 2025, prices for Santiago to San Francisco flights are approximately 21% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found

$255

Fastest flight time

14h 40m

Direct flights

None

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Santiago in the past 72 hours is $255. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $458.
The fastest flight from Santiago to San Francisco takes 14h 40m
There are no direct flights from Santiago to San Francisco. Popular non-direct route for this connection is Santiago Arturo Merino Benitez Airport - San Francisco Airport.
There is 1 airport near San Francisco: San Francisco (SFO)
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5935.3 mi. 14h 53m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $513Free CancellationRating
7.4
8,925 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $518Free CancellationRating
7.5
1,510 reviews
Search Copa Airlines flights
DeltaPriceFrom $547Free CancellationRating
8.0
7,981 reviews
Search Delta flights
LATAM AirlinesPriceFrom $552Free CancellationRating
7.5
1,844 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $612Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Calistoga
Sonoma
Hayward
Bodega Bay
Roseville
Santa Clara
Big Sur
Daly City
Fremont
Berkeley
Walnut Creek
Half Moon Bay
South San Francisco
Vallejo
Redwood City
Sunnyvale
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 8/23
Sat 8/30
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States