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Cheap flights from Santiago to San Francisco from $426

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
9:55 pm - 1:45 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 50m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
7:05 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 30m1 stop Los Angeles
$703LATAM Airlines
Thu, Nov 5 - Thu, Dec 3
LATAM Airlines Logo
9:55 pm - 1:45 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 50m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
7:05 am - 5:05 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 00m2 stops Los Angeles Miami
$709LATAM Airlines
Mon, Nov 2 - Tue, Nov 24
Copa Airlines Logo
12:23 pm - 6:25 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
34h 02m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:36 pm - 8:15 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 39m1 stop Panama City Tocumen Intl
$738Copa Airlines
Tue, Oct 27 - Tue, Nov 10
Delta Logo
11:55 pm - 3:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 40m1 stop Los Angeles
Delta Logo
6:00 am - 7:00 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 00m2 stops Atlanta Hartsfield-Jackson Miami
$742Delta
Thu, Nov 26 - Thu, Dec 3
Delta Logo
11:10 pm - 8:06 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
25h 56m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 7:30 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
$742Delta
Mon, Nov 2 - Wed, Nov 11
American Airlines Logo
10:30 pm - 1:22 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 52m2 stops Miami Los Angeles
American Airlines Logo
8:55 am - 9:25 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 30m2 stops Dallas/Fort Worth Miami
$742American Airlines
Tue, Nov 24 - Mon, Nov 30
United Airlines Logo
10:45 pm - 3:02 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
21h 17m1 stop Houston George Bush Intcntl
United Airlines Logo
7:15 am - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 35m1 stop Houston George Bush Intcntl
$744United Airlines
Sun, Nov 1 - Wed, Nov 25
United Airlines Logo
10:45 pm - 10:46 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
17h 01m1 stop Houston George Bush Intcntl
United Airlines Logo
12:45 am - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 05m1 stop Houston George Bush Intcntl
$744United Airlines
Tue, Nov 3 - Tue, Nov 24
American Airlines Logo
10:15 pm - 2:41 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 26m2 stops Miami Charlotte Douglas
American Airlines Logo
7:00 am - 8:45 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 45m2 stops Los Angeles Miami
$755American Airlines
Tue, Oct 27 - Tue, Nov 10
Copa Airlines Logo
12:20 pm - 5:25 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
34h 05m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:22 am - 8:07 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
14h 45m1 stop Panama City Tocumen Intl
$783Copa Airlines
Fri, Dec 11 - Sun, Mar 28

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LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Nov 5
SCL9:55 pmSantiago Arturo Merino Benitez
20h 50m
2 stops
SFO1:45 pmSan Francisco
Dec 3
SFO7:05 amSan Francisco
17h 30m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$703
LATAM Airlines
Nov 2
SCL9:55 pmSantiago Arturo Merino Benitez
20h 50m
2 stops
SFO1:45 pmSan Francisco
Nov 24
SFO7:05 amSan Francisco
17h 00m
2 stops
SCL5:05 amSantiago Arturo Merino Benitez
$709
LATAM Airlines
Oct 27
SCL4:10 amSantiago Arturo Merino Benitez
22h 05m
2 stops
SFO10:15 pmSan Francisco
Nov 10
SFO8:00 amSan Francisco
18h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$719

Delta flights from Santiago to San Francisco

Our best Delta deals on Santiago to San Francisco flight tickets
Delta
Nov 24
SCL11:10 pmSantiago Arturo Merino Benitez
23h 06m
2 stops
SFO5:16 pmSan Francisco
Nov 30
SFO7:05 amSan Francisco
17h 30m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$742
Delta
Nov 7
SCL11:10 pmSantiago Arturo Merino Benitez
20h 32m
1 stop
SFO2:42 pmSan Francisco
Nov 15
SFO7:00 amSan Francisco
19h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$743
Delta
Nov 2
SCL11:10 pmSantiago Arturo Merino Benitez
25h 56m
1 stop
SFO8:06 pmSan Francisco
Nov 11
SFO6:00 amSan Francisco
20h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$744

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 11/5

9:55 pm-1:45 pm

2 stops20h 50m

San Francisco

Thu 12/3

7:05 am-5:35 am

1 stop17h 30m

$703
Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/2

9:55 pm-1:45 pm

2 stops20h 50m

San Francisco

Tue 11/24

7:05 am-5:05 am

2 stops17h 00m

$709

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/27

12:23 pm-6:25 pm

1 stop34h 02m

San Francisco

Tue 11/10

7:36 pm-8:15 pm

1 stop19h 39m

$738

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 11/26

11:55 pm-3:35 pm

1 stop20h 40m

San Francisco

Thu 12/3

6:00 am-7:00 am

2 stops20h 00m

$742

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/2

11:10 pm-8:06 pm

1 stop25h 56m

San Francisco

Wed 11/11

6:00 am-7:30 am

2 stops20h 30m

$742

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 11/24

10:30 pm-1:22 pm

2 stops19h 52m

San Francisco

Mon 11/30

8:55 am-9:25 am

2 stops19h 30m

$742

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Sun 11/1

10:45 pm-3:02 pm

1 stop21h 17m

San Francisco

Wed 11/25

7:15 am-8:50 am

1 stop20h 35m

$744

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 11/3

10:45 pm-10:46 am

1 stop17h 01m

San Francisco

Tue 11/24

12:45 am-8:50 am

1 stop27h 05m

$744

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/27

10:15 pm-2:41 pm

2 stops20h 26m

San Francisco

Tue 11/10

7:00 am-8:45 am

2 stops20h 45m

$755

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 12/11

12:20 pm-5:25 pm

1 stop34h 05m

San Francisco

Sun 3/28

1:22 am-8:07 pm

1 stop14h 45m

$783

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $666 to $1,026.
The lowest price recently found on this route was $703.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $616.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $703 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $640 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 2% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of October 2026, prices for Santiago to San Francisco flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found

$426

Fastest flight time

15h 30m

Direct flights

None
The best one-way flight to San Francisco from Santiago in the past 72 hours is $426. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $703.
The fastest flight from Santiago to San Francisco takes 15h 30m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 15h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,549 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $494Free CancellationRating
7.4
1,972 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $515Free CancellationRating
7.0
12,167 reviews
Search American Airlines flights
DeltaPriceFrom $531Free CancellationRating
7.8
8,650 reviews
Search Delta flights
AviancaPriceFrom $542Free CancellationRating
6.5
2,553 reviews
Search Avianca flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
10,363 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Hayward
Bodega Bay
Walnut Creek
Santa Clara
Fremont
Berkeley
Sunnyvale
Half Moon Bay
Vallejo
Roseville
Salinas
Milpitas
Sonoma
Pacific Grove
Palo Alto
Daly City

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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