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Cheap flights from Santiago to San Francisco from $455

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
6:40 am - 11:11 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 31m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
1:00 pm - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
13h 35m1 stop Los Angeles
$811LATAM Airlines
Wed, Apr 21 - Fri, Apr 30
LATAM Airlines Logo
9:55 pm - 11:04 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 09m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
7:00 am - 5:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 20m2 stops Los Angeles Lima J Chavez Intl
$811LATAM Airlines
Thu, Feb 18 - Thu, Mar 4
Avianca Logo
6:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 11:20 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$814Avianca
Wed, Apr 28 - Sun, May 9
Avianca Logo
6:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 11:20 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$814Avianca
Wed, Mar 31 - Wed, Apr 14
Air Canada Logo
9:55 pm - 1:10 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 15m1 stop Toronto Pearson Intl
Air Canada Logo
8:25 am - 5:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 25m1 stop Montreal Pierre Elliott Trudeau Intl
$875Air Canada
Thu, Dec 10 - Mon, Mar 15
Delta Logo
9:55 pm - 11:02 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 07m2 stops Lima J Chavez Intl Los Angeles
Delta Logo
8:55 am - 11:15 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 20m2 stops Los Angeles Sao Paulo Guarulhos Intl
$876Delta
Thu, Feb 4 - Wed, Feb 17
Delta Logo
9:55 pm - 11:02 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 07m2 stops Lima J Chavez Intl Los Angeles
Delta Logo
8:55 am - 11:15 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 20m2 stops Los Angeles Sao Paulo Guarulhos Intl
$876Delta
Tue, Feb 2 - Wed, Feb 17
United Airlines Logo
10:45 pm - 10:50 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
17h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 am - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
22h 50m1 stop Houston George Bush Intcntl
$876United Airlines
Tue, Feb 2 - Sun, Feb 14
United Airlines Logo
10:45 pm - 7:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
25h 50m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 am - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
22h 50m1 stop Houston George Bush Intcntl
$876United Airlines
Thu, Dec 17 - Tue, Dec 29
Air Canada Logo
9:55 pm - 11:10 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 15m1 stop Toronto Pearson Intl
Air Canada Logo
4:40 pm - 12:15 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
38h 35m1 stop Toronto Pearson Intl
$900Air Canada
Mon, Dec 7 - Thu, Jan 14

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Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Mar 31
SCL6:40 amSantiago Arturo Merino Benitez
19h 55m
2 stops
SFO10:35 pmSan Francisco
Apr 9
SFO2:15 pmSan Francisco
21h 00m
2 stops
SCL2:15 pmSantiago Arturo Merino Benitez
$814
Avianca
Feb 3
SCL7:30 amSantiago Arturo Merino Benitez
19h 10m
2 stops
SFO9:40 pmSan Francisco
Feb 16
SFO1:15 pmSan Francisco
20h 55m
2 stops
SCL3:10 pmSantiago Arturo Merino Benitez
$816
Avianca
Mar 31
SCL6:40 amSantiago Arturo Merino Benitez
19h 55m
2 stops
SFO10:35 pmSan Francisco
Apr 9
SFO2:15 pmSan Francisco
21h 00m
2 stops
SCL2:15 pmSantiago Arturo Merino Benitez
$824

LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Feb 18
SCL11:55 pmSantiago Arturo Merino Benitez
16h 09m
1 stop
SFO11:04 amSan Francisco
Mar 4
SFO7:00 amSan Francisco
17h 20m
2 stops
SCL5:20 amSantiago Arturo Merino Benitez
$811
LATAM Airlines
Feb 5
SCL9:55 pmSantiago Arturo Merino Benitez
19h 07m
2 stops
SFO12:02 pmSan Francisco
Mar 5
SFO7:00 amSan Francisco
17h 35m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$828
LATAM Airlines
Mar 31
SCL11:25 pmSantiago Arturo Merino Benitez
15h 39m
1 stop
SFO11:04 amSan Francisco
Apr 9
SFO8:55 amSan Francisco
17h 40m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$829

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 4/21

6:40 am-11:11 pm

2 stops19h 31m

San Francisco

Fri 4/30

1:00 pm-5:35 am

1 stop13h 35m

$811

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

9:55 pm-11:04 am

2 stops18h 09m

San Francisco

Thu 3/4

7:00 am-5:20 am

2 stops17h 20m

$811

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 4/28

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Sun 5/9

11:55 pm-11:20 pm

2 stops20h 25m

$814

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 3/31

6:40 am-10:35 pm

2 stops19h 55m

San Francisco

Wed 4/14

11:55 pm-11:20 pm

2 stops20h 25m

$814

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/10

9:55 pm-1:10 pm

1 stop20h 15m

San Francisco

Mon 3/15

8:25 am-5:50 am

1 stop17h 25m

$875

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/4

9:55 pm-11:02 am

2 stops18h 07m

San Francisco

Wed 2/17

8:55 am-11:15 am

2 stops21h 20m

$876

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 2/2

9:55 pm-11:02 am

2 stops18h 07m

San Francisco

Wed 2/17

8:55 am-11:15 am

2 stops21h 20m

$876

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 2/2

10:45 pm-10:50 am

1 stop17h 05m

San Francisco

Sun 2/14

5:00 am-8:50 am

1 stop22h 50m

$876

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/17

10:45 pm-7:35 pm

1 stop25h 50m

San Francisco

Tue 12/29

5:00 am-8:50 am

1 stop22h 50m

$876

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 12/7

9:55 pm-11:10 am

1 stop18h 15m

San Francisco

Thu 1/14

4:40 pm-12:15 pm

1 stop38h 35m

$900

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $605 to $1,012.
The lowest price recently found on this route was $811.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $640.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $717 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $640 on momondo.

How have Santiago to San Francisco flight prices changed over time?

As of October 2026, prices for Santiago to San Francisco flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found

$455

Fastest flight time

16h 06m

Direct flights

None
The best one-way flight to San Francisco from Santiago in the past 72 hours is $455. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $811.
The fastest flight from Santiago to San Francisco takes 16h 06m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 16h 06m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,554 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $494Free CancellationRating
7.4
1,970 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $515Free CancellationRating
7.0
12,210 reviews
Search American Airlines flights
DeltaPriceFrom $531Free CancellationRating
7.8
8,690 reviews
Search Delta flights
AviancaPriceFrom $542Free CancellationRating
6.5
2,549 reviews
Search Avianca flights
United AirlinesPriceFrom $571Free CancellationRating
7.3
10,451 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Hayward
Santa Clara
Walnut Creek
Bodega Bay
Fremont
Berkeley
Sunnyvale
Half Moon Bay
Vallejo
Roseville
Salinas
Sonoma
Milpitas
Palo Alto
Daly City
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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