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Cheap flights from Santiago to San Francisco from $394

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
7:40 am - 11:55 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 15m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
12:00 am - 1:05 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 05m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$744Avianca
Tue, Oct 20 - Mon, Oct 26
Avianca Logo
7:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
2:15 pm - 3:10 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 55m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$744Avianca
Mon, Oct 19 - Mon, Oct 26
Delta Logo
9:50 pm - 5:11 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
24h 21m1 stop Atlanta Hartsfield-Jackson
Delta Logo
1:00 pm - 3:00 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 00m2 stops Los Angeles Lima J Chavez Intl
$748Delta
Thu, Feb 4 - Thu, Feb 11
LATAM Airlines Logo
9:55 pm - 11:04 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 09m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
7:00 am - 5:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 20m2 stops Los Angeles Lima J Chavez Intl
$761LATAM Airlines
Thu, Feb 18 - Thu, Mar 4
LATAM Airlines Logo
11:55 pm - 11:04 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 09m1 stop Los Angeles
LATAM Airlines Logo
7:00 am - 5:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 20m2 stops Los Angeles Lima J Chavez Intl
$761LATAM Airlines
Thu, Feb 18 - Thu, Mar 4
Multiple Airlines Logo
9:50 pm - 12:45 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 55m1 stop Atlanta Hartsfield-Jackson
Multiple Airlines Logo
6:00 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
18h 35m1 stop Los Angeles
$776Multiple Airlines
Mon, Feb 15 - Sun, Feb 21
Copa Airlines Logo
1:27 am - 5:25 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 58m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:22 am - 8:07 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
14h 45m1 stop Panama City Tocumen Intl
$783Copa Airlines
Thu, Dec 10 - Sun, Mar 28
Copa Airlines Logo
3:19 am - 11:12 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
24h 53m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:33 am - 3:43 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
22h 10m1 stop Panama City Tocumen Intl
$783Copa Airlines
Tue, Nov 17 - Sun, Nov 29
Delta Logo
8:40 am - 12:15 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 35m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
Delta Logo
11:55 am - 8:40 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 45m2 stops New York John F Kennedy Intl Sao Paulo Guarulhos Intl
$786Delta
Thu, Feb 4 - Thu, Feb 11
Multiple Airlines Logo
7:40 am - 10:54 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 14m2 stops Lima J Chavez Intl Los Angeles
Multiple Airlines Logo
11:55 pm - 10:41 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
31h 46m3 stops Mexico City Benito Juarez Lima J Chavez Intl Buenos Aires Jorge Newbery
$867Multiple Airlines
Sun, Dec 13 - Tue, Apr 6

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Delta flights from Santiago to San Francisco

Our best Delta deals on Santiago to San Francisco flight tickets
Delta
Dec 6
SCL11:10 pmSantiago Arturo Merino Benitez
20h 23m
2 stops
SFO2:33 pmSan Francisco
Mar 2
SFO10:00 pmSan Francisco
27h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
$786
Delta
Feb 10
SCL11:10 pmSantiago Arturo Merino Benitez
18h 35m
1 stop
SFO12:45 pmSan Francisco
Feb 17
SFO4:15 pmSan Francisco
20h 45m
2 stops
SCL6:00 pmSantiago Arturo Merino Benitez
$795
Delta
Dec 2
SCL9:55 pmSantiago Arturo Merino Benitez
17h 59m
2 stops
SFO10:54 amSan Francisco
Jan 9
SFO7:00 amSan Francisco
19h 40m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
$830

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Oct 19
SCL7:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Oct 26
SFO2:15 pmSan Francisco
20h 55m
2 stops
SCL3:10 pmSantiago Arturo Merino Benitez
$744
Avianca
Nov 6
SCL7:30 amSantiago Arturo Merino Benitez
19h 10m
2 stops
SFO9:40 pmSan Francisco
Nov 13
SFO1:15 pmSan Francisco
20h 55m
2 stops
SCL3:10 pmSantiago Arturo Merino Benitez
$745
Avianca
Oct 14
SCL7:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Oct 21
SFO2:15 pmSan Francisco
21h 00m
2 stops
SCL3:15 pmSantiago Arturo Merino Benitez
$748

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/20

7:40 am-11:55 pm

2 stops20h 15m

San Francisco

Mon 10/26

12:00 am-1:05 am

2 stops21h 05m

$744

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 10/19

7:40 am-10:35 pm

2 stops18h 55m

San Francisco

Mon 10/26

2:15 pm-3:10 pm

2 stops20h 55m

$744

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/4

9:50 pm-5:11 pm

1 stop24h 21m

San Francisco

Thu 2/11

1:00 pm-3:00 pm

2 stops21h 00m

$748

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

9:55 pm-11:04 am

2 stops18h 09m

San Francisco

Thu 3/4

7:00 am-5:20 am

2 stops17h 20m

$761
Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

11:55 pm-11:04 am

1 stop16h 09m

San Francisco

Thu 3/4

7:00 am-5:20 am

2 stops17h 20m

$761

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 2/15

9:50 pm-12:45 pm

1 stop19h 55m

San Francisco

Sun 2/21

6:00 am-5:35 am

1 stop18h 35m

$776

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/10

1:27 am-5:25 pm

1 stop20h 58m

San Francisco

Sun 3/28

1:22 am-8:07 pm

1 stop14h 45m

$783

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 11/17

3:19 am-11:12 pm

1 stop24h 53m

San Francisco

Sun 11/29

12:33 am-3:43 am

1 stop22h 10m

$783

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/4

8:40 am-12:15 am

2 stops20h 35m

San Francisco

Thu 2/11

11:55 am-8:40 pm

2 stops27h 45m

$786

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Sun 12/13

7:40 am-10:54 pm

2 stops20h 14m

San Francisco

Tue 4/6

11:55 pm-10:41 am

3 stops31h 46m

$867

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $557 to $945.
The lowest price recently found on this route was $744.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $616.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $687 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $640 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 2% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of September 2026, prices for Santiago to San Francisco flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found

$394

Fastest flight time

15h 31m

Direct flights

None
The best one-way flight to San Francisco from Santiago in the past 72 hours is $394. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $744.
The fastest flight from Santiago to San Francisco takes 15h 31m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 15h 31m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,544 reviews
Search Copa Airlines flights
AviancaPriceFrom $448Free CancellationRating
6.5
2,554 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.0
12,097 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $494Free CancellationRating
7.4
1,982 reviews
Search LATAM Airlines flights
DeltaPriceFrom $531Free CancellationRating
7.8
8,609 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
10,247 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Berkeley
Hayward
Bodega Bay
Fremont
Santa Clara
Walnut Creek
Sunnyvale
Vallejo
Half Moon Bay
Roseville
Salinas
Sonoma
Daly City
Milpitas
Pacific Grove
Marina

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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