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Cheap flights from Santiago to San Francisco from $362

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
7:30 am - 9:23 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 53m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
7:05 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 30m1 stop Los Angeles
$524LATAM Airlines
Mon, Nov 16 - Tue, Nov 24
LATAM Airlines Logo
11:55 pm - 1:52 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 57m1 stop Los Angeles
LATAM Airlines Logo
7:05 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
17h 30m1 stop Los Angeles
$524LATAM Airlines
Mon, Nov 16 - Tue, Nov 24
Delta Logo
11:10 pm - 3:59 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 49m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 7:15 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 15m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
$536Delta
Fri, Oct 30 - Sat, Nov 7
Delta Logo
8:40 pm - 2:52 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
22h 12m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl
Delta Logo
6:00 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 35m2 stops Atlanta Hartsfield-Jackson Miami
$536Delta
Mon, Sep 28 - Mon, Oct 5
Multiple Airlines Logo
9:30 am - 1:20 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
31h 50m1 stop Mexico City Benito Juarez
Multiple Airlines Logo
7:10 am - 5:35 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
18h 25m1 stop Los Angeles
$600Multiple Airlines
Tue, Sep 22 - Thu, Oct 8
Multiple Airlines Logo
11:55 pm - 11:04 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 09m1 stop Los Angeles
Multiple Airlines Logo
10:30 pm - 7:00 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 30m1 stop Mexico City Benito Juarez
$605Multiple Airlines
Mon, Feb 22 - Sun, Feb 28
Avianca Logo
7:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
12:00 am - 1:05 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 05m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$706Avianca
Sat, Oct 24 - Sat, Oct 31
Avianca Logo
7:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
1:15 pm - 3:10 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 55m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$706Avianca
Fri, Sep 25 - Sat, Dec 5
United Airlines Logo
9:45 pm - 10:10 amSCL  Santiago Arturo Merino Benitez-SFO San Francisco
16h 25m1 stop Houston George Bush Intcntl
United Airlines Logo
11:59 pm - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
27h 51m1 stop Houston George Bush Intcntl
$710United Airlines
Fri, Oct 30 - Sat, Nov 7
United Airlines Logo
9:45 pm - 12:53 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 08m1 stop Houston George Bush Intcntl
United Airlines Logo
6:35 pm - 8:50 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
33h 15m1 stop Houston George Bush Intcntl
$710United Airlines
Fri, Oct 30 - Sat, Nov 7

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LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Nov 16
SCL11:55 pmSantiago Arturo Merino Benitez
18h 57m
1 stop
SFO1:52 pmSan Francisco
Nov 24
SFO7:05 amSan Francisco
17h 30m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$524
LATAM Airlines
Dec 11
SCL9:55 pmSantiago Arturo Merino Benitez
17h 59m
2 stops
SFO10:54 amSan Francisco
Mar 29
SFO7:00 amSan Francisco
19h 25m
2 stops
SCL6:25 amSantiago Arturo Merino Benitez
$530
LATAM Airlines
Dec 17
SCL8:40 amSantiago Arturo Merino Benitez
17h 46m
2 stops
SFO9:26 pmSan Francisco
Jan 5
SFO6:00 amSan Francisco
20h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$534

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
Sep 25
SCL7:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Dec 5
SFO1:15 pmSan Francisco
20h 55m
2 stops
SCL3:10 pmSantiago Arturo Merino Benitez
$706
Avianca
Sep 19
SCL7:40 amSantiago Arturo Merino Benitez
18h 55m
2 stops
SFO10:35 pmSan Francisco
Oct 18
SFO11:55 pmSan Francisco
20h 25m
2 stops
SCL12:20 amSantiago Arturo Merino Benitez
$708
Avianca
Jan 29
SCL7:30 amSantiago Arturo Merino Benitez
19h 10m
2 stops
SFO9:40 pmSan Francisco
Feb 19
SFO1:15 pmSan Francisco
20h 55m
2 stops
SCL3:10 pmSantiago Arturo Merino Benitez
$712

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/16

7:30 am-9:23 pm

2 stops18h 53m

San Francisco

Tue 11/24

7:05 am-5:35 am

1 stop17h 30m

$524

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 11/16

11:55 pm-1:52 pm

1 stop18h 57m

San Francisco

Tue 11/24

7:05 am-5:35 am

1 stop17h 30m

$524

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/30

11:10 pm-3:59 pm

1 stop20h 49m

San Francisco

Sat 11/7

6:00 am-7:15 am

2 stops20h 15m

$536

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 9/28

8:40 pm-2:52 pm

2 stops22h 12m

San Francisco

Mon 10/5

6:00 am-5:35 am

2 stops19h 35m

$536

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 9/22

9:30 am-1:20 pm

1 stop31h 50m

San Francisco

Thu 10/8

7:10 am-5:35 am

1 stop18h 25m

$600

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 2/22

11:55 pm-11:04 am

1 stop16h 09m

San Francisco

Sun 2/28

10:30 pm-7:00 am

1 stop27h 30m

$605

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Sat 10/24

7:40 am-10:35 pm

2 stops18h 55m

San Francisco

Sat 10/31

12:00 am-1:05 am

2 stops21h 05m

$706

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 9/25

7:40 am-10:35 pm

2 stops18h 55m

San Francisco

Sat 12/5

1:15 pm-3:10 pm

2 stops20h 55m

$706

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/30

9:45 pm-10:10 am

1 stop16h 25m

San Francisco

Sat 11/7

11:59 pm-8:50 am

1 stop27h 51m

$710

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 10/30

9:45 pm-12:53 pm

1 stop19h 08m

San Francisco

Sat 11/7

6:35 pm-8:50 am

1 stop33h 15m

$710

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $630 to $903.
The lowest price recently found on this route was $524.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $599.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $672 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $619 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 30% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of August 2026, prices for Santiago to San Francisco flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found

$362

Fastest flight time

17h 18m

Direct flights

None
The best one-way flight to San Francisco from Santiago in the past 72 hours is $362. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $524.
The fastest flight from Santiago to San Francisco takes 17h 18m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 17h 18m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $311Free CancellationRating
7.6
1,550 reviews
Search Copa Airlines flights
AviancaPriceFrom $448Free CancellationRating
6.5
2,556 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
12,019 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $494Free CancellationRating
7.4
1,987 reviews
Search LATAM Airlines flights
DeltaPriceFrom $559Free CancellationRating
7.8
8,533 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
10,146 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Bodega Bay
Fremont
Berkeley
Hayward
Walnut Creek
Santa Clara
Sunnyvale
Vallejo
Roseville
Salinas
Sonoma
Daly City
Milpitas
Half Moon Bay
Burlingame
Marina

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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