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Cheap flights from Santiago to San Francisco from $278

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:50 pm - 2:38 pm
SCL
-
SFO
20h 48m
2 stops
American Airlines Logo
11:45 am - 8:05 am
SFO
-
SCL
17h 20m
1 stop
$555American Airlines
Thu, Aug 27 - Fri, Sep 4
American Airlines Logo
8:50 pm - 4:00 pm
SCL
-
SFO
22h 10m
2 stops
American Airlines Logo
10:50 am - 6:25 am
SFO
-
SCL
16h 35m
1 stop
$556American Airlines
Wed, Aug 5 - Tue, Aug 11
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
18h 55m
2 stops
Avianca Logo
2:15 pm - 2:15 pm
SFO
-
SCL
21h 00m
2 stops
$557Avianca
Wed, Jul 22 - Sun, Aug 16
LATAM Airlines Logo
8:40 pm - 10:20 am
SCL
-
SFO
16h 40m
1 stop
LATAM Airlines Logo
9:30 am - 5:35 am
SFO
-
SCL
17h 05m
1 stop
$558LATAM Airlines
Thu, Jul 30 - Thu, Aug 13
Copa Airlines Logo
1:44 am - 11:40 pm
SCL
-
SFO
25h 56m
1 stop
Copa Airlines Logo
1:12 am - 6:10 am
SFO
-
SCL
24h 58m
1 stop
$561Copa Airlines
Tue, Oct 13 - Thu, Oct 22
Multiple Airlines Logo
11:25 pm - 11:27 am
SCL
-
SFO
15h 02m
1 stop
Multiple Airlines Logo
6:00 am - 7:15 am
SFO
-
SCL
22h 15m
1 stop
$566Multiple Airlines
Mon, Jul 6 - Mon, Jul 13
Copa Airlines Logo
4:21 am - 11:40 pm
SCL
-
SFO
22h 19m
1 stop
Copa Airlines Logo
1:12 am - 5:14 am
SFO
-
SCL
25h 02m
1 stop
$568Copa Airlines
Thu, Jul 23 - Tue, Aug 4
Avianca Logo
3:20 pm - 12:50 pm
SCL
-
SFO
24h 30m
2 stops
Avianca Logo
11:55 pm - 4:45 am
SFO
-
SCL
25h 50m
2 stops
$571Avianca
Wed, Jul 22 - Tue, Aug 18
Avianca Logo
6:40 am - 10:35 pm
SCL
-
SFO
42h 55m
2 stops
Avianca Logo
7:45 am - 4:45 am
SFO
-
SCL
42h 00m
3 stops
$573Avianca
Wed, Jul 22 - Tue, Aug 18
Avianca Logo
3:20 pm - 12:50 pm
SCL
-
SFO
24h 30m
2 stops
Avianca Logo
11:55 pm - 4:45 am
SFO
-
SCL
25h 50m
2 stops
$574Avianca
Mon, Jul 6 - Mon, Jul 13

LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Jul 30
SCL8:40 pmSantiago Arturo Merino Benitez
16h 40m
1 stop
SFO10:20 amSan Francisco
Aug 13
SFO9:30 amSan Francisco
17h 05m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$558
LATAM Airlines
Oct 8
SCL4:30 pmSantiago Arturo Merino Benitez
47h 29m
2 stops
SFO11:59 amSan Francisco
Oct 18
SFO6:00 amSan Francisco
22h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$577
LATAM Airlines
Jul 24
SCL11:25 pmSantiago Arturo Merino Benitez
19h 19m
1 stop
SFO3:44 pmSan Francisco
Jul 31
SFO11:59 pmSan Francisco
51h 56m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
$598

Copa Airlines flights from Santiago to San Francisco

Our best Copa Airlines deals on Santiago to San Francisco flight tickets
Copa Airlines
Oct 13
SCL1:44 amSantiago Arturo Merino Benitez
25h 56m
1 stop
SFO11:40 pmSan Francisco
Oct 22
SFO1:12 amSan Francisco
24h 58m
1 stop
SCL6:10 amSantiago Arturo Merino Benitez
$561
Copa Airlines
Jul 23
SCL4:21 amSantiago Arturo Merino Benitez
22h 19m
1 stop
SFO11:40 pmSan Francisco
Aug 4
SFO1:12 amSan Francisco
25h 02m
1 stop
SCL5:14 amSantiago Arturo Merino Benitez
$568
Copa Airlines
Aug 13
SCL2:14 amSantiago Arturo Merino Benitez
24h 26m
1 stop
SFO11:40 pmSan Francisco
Aug 27
SFO1:12 amSan Francisco
22h 48m
1 stop
SCL3:00 amSantiago Arturo Merino Benitez
$584

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 4, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/27

8:50 pm-2:38 pm

2 stops20h 48m

San Francisco

Fri 9/4

11:45 am-8:05 am

1 stop17h 20m

$555

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/5

8:50 pm-4:00 pm

2 stops22h 10m

San Francisco

Tue 8/11

10:50 am-6:25 am

1 stop16h 35m

$556

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 7/22

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Sun 8/16

2:15 pm-2:15 pm

2 stops21h 00m

$557
Quickest round-trip

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/30

8:40 pm-10:20 am

1 stop16h 40m

San Francisco

Thu 8/13

9:30 am-5:35 am

1 stop17h 05m

$558

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 10/13

1:44 am-11:40 pm

1 stop25h 56m

San Francisco

Thu 10/22

1:12 am-6:10 am

1 stop24h 58m

$561

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 7/6

11:25 pm-11:27 am

1 stop15h 02m

San Francisco

Mon 7/13

6:00 am-7:15 am

1 stop22h 15m

$566

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/23

4:21 am-11:40 pm

1 stop22h 19m

San Francisco

Tue 8/4

1:12 am-5:14 am

1 stop25h 02m

$568

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 7/22

3:20 pm-12:50 pm

2 stops24h 30m

San Francisco

Tue 8/18

11:55 pm-4:45 am

2 stops25h 50m

$571

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 7/22

6:40 am-10:35 pm

2 stops42h 55m

San Francisco

Tue 8/18

7:45 am-4:45 am

3 stops42h 00m

$573

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 7/6

3:20 pm-12:50 pm

2 stops24h 30m

San Francisco

Mon 7/13

11:55 pm-4:45 am

2 stops25h 50m

$574

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $571.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $652 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $599 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 30% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of June 2026, prices for Santiago to San Francisco flights are approximately 41% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Fastest flight time

16h 38m

Direct flights

None
The fastest flight from Santiago to San Francisco takes 16h 38m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
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Frequently asked questions about flying from Santiago to San Francisco

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 16h 38m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $433Free CancellationRating
6.5
2,528 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $501Free CancellationRating
7.4
1,919 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $511Free CancellationRating
7.5
1,568 reviews
Search Copa Airlines flights
DeltaPriceFrom $559Free CancellationRating
7.8
8,395 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
9,774 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Hayward
Walnut Creek
Bodega Bay
Roseville
Santa Clara
Berkeley
Fremont
Vallejo
Sunnyvale
Big Sur
South San Francisco
Calistoga
Daly City
Pacific Grove
Salinas
Burlingame

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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