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Cheap flights from Santiago to San Francisco from $457

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 3/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
11:25 pm - 11:59 am
SCL
-
SFO
15h 34m
1 stop
LATAM Airlines Logo
8:55 am - 5:35 am
SFO
-
SCL
17h 40m
1 stop
$528LATAM Airlines
Sat, May 23 - Thu, Jun 4
United Airlines Logo
10:45 pm - 8:45 pm
SCL
-
SFO
27h 00m
1 stop
United Airlines Logo
12:43 am - 8:50 am
SFO
-
SCL
27h 07m
1 stop
$530United Airlines
Mon, Feb 23 - Sun, Mar 1
LATAM Airlines Logo
8:40 pm - 3:11 pm
SCL
-
SFO
21h 31m
2 stops
LATAM Airlines Logo
7:00 am - 7:15 am
SFO
-
SCL
21h 15m
2 stops
$532LATAM Airlines
Fri, May 15 - Tue, May 19
LATAM Airlines Logo
11:00 pm - 5:10 pm
SCL
-
SFO
21h 10m
2 stops
LATAM Airlines Logo
11:05 am - 5:35 am
SFO
-
SCL
15h 30m
1 stop
$533LATAM Airlines
Mon, May 11 - Mon, Jun 8
LATAM Airlines Logo
7:45 am - 10:25 am
SCL
-
SFO
29h 40m
2 stops
LATAM Airlines Logo
11:00 am - 5:35 am
SFO
-
SCL
15h 35m
1 stop
$535LATAM Airlines
Fri, Apr 17 - Sun, May 3
LATAM Airlines Logo
12:20 am - 12:35 am
SCL
-
SFO
28h 15m
2 stops
LATAM Airlines Logo
11:40 pm - 1:35 pm
SFO
-
SCL
34h 55m
2 stops
$538LATAM Airlines
Thu, Mar 19 - Thu, Apr 30
LATAM Airlines Logo
4:35 am - 12:35 am
SCL
-
SFO
24h 00m
2 stops
LATAM Airlines Logo
8:55 am - 7:40 am
SFO
-
SCL
18h 45m
2 stops
$540LATAM Airlines
Thu, Mar 12 - Thu, Mar 19
Delta Logo
11:00 pm - 7:35 pm
SCL
-
SFO
23h 35m
2 stops
Delta Logo
7:00 am - 6:55 am
SFO
-
SCL
20h 55m
2 stops
$541Delta
Mon, May 11 - Mon, Jun 8
Copa Airlines Logo
5:21 am - 11:40 pm
SCL
-
SFO
22h 19m
1 stop
Copa Airlines Logo
1:23 am - 11:26 pm
SFO
-
SCL
19h 03m
1 stop
$543Copa Airlines
Fri, Mar 20 - Wed, Apr 29
Avianca Logo
2:30 pm - 11:55 pm
SCL
-
SFO
36h 25m
2 stops
Avianca Logo
11:55 pm - 4:15 am
SFO
-
SCL
25h 20m
2 stops
$549Avianca
Wed, May 13 - Sat, May 30

Avianca flights from Santiago to San Francisco

Our best Avianca deals on Santiago to San Francisco flight tickets
Avianca
May 13
SCL2:30 pmSantiago Arturo Merino Benitez
36h 25m
2 stops
SFO11:55 pmSan Francisco
May 30
SFO11:55 pmSan Francisco
25h 20m
2 stops
SCL4:15 amSantiago Arturo Merino Benitez
$549
Avianca
Mar 9
SCL4:25 pmSantiago Arturo Merino Benitez
35h 15m
2 stops
SFO11:40 pmSan Francisco
Mar 19
SFO2:20 pmSan Francisco
21h 00m
2 stops
SCL3:20 pmSantiago Arturo Merino Benitez
$571
Avianca
Mar 10
SCL7:25 amSantiago Arturo Merino Benitez
20h 15m
2 stops
SFO11:40 pmSan Francisco
Jun 5
SFO11:55 pmSan Francisco
19h 35m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
$578

LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
May 23
SCL11:25 pmSantiago Arturo Merino Benitez
15h 34m
1 stop
SFO11:59 amSan Francisco
Jun 4
SFO8:55 amSan Francisco
17h 40m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$528
LATAM Airlines
May 15
SCL8:40 pmSantiago Arturo Merino Benitez
21h 31m
2 stops
SFO3:11 pmSan Francisco
May 19
SFO7:00 amSan Francisco
21h 15m
2 stops
SCL7:15 amSantiago Arturo Merino Benitez
$532
LATAM Airlines
May 11
SCL11:00 pmSantiago Arturo Merino Benitez
21h 10m
2 stops
SFO5:10 pmSan Francisco
Jun 8
SFO11:05 amSan Francisco
15h 30m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$533

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sat 5/23

11:25 pm-11:59 am

1 stop15h 34m

San Francisco

Thu 6/4

8:55 am-5:35 am

1 stop17h 40m

$528

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 2/23

10:45 pm-8:45 pm

1 stop27h 00m

San Francisco

Sun 3/1

12:43 am-8:50 am

1 stop27h 07m

$530

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 5/15

8:40 pm-3:11 pm

2 stops21h 31m

San Francisco

Tue 5/19

7:00 am-7:15 am

2 stops21h 15m

$532

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 5/11

11:00 pm-5:10 pm

2 stops21h 10m

San Francisco

Mon 6/8

11:05 am-5:35 am

1 stop15h 30m

$533

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 4/17

7:45 am-10:25 am

2 stops29h 40m

San Francisco

Sun 5/3

11:00 am-5:35 am

1 stop15h 35m

$535

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 3/19

12:20 am-12:35 am

2 stops28h 15m

San Francisco

Thu 4/30

11:40 pm-1:35 pm

2 stops34h 55m

$538

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 3/12

4:35 am-12:35 am

2 stops24h 00m

San Francisco

Thu 3/19

8:55 am-7:40 am

2 stops18h 45m

$540

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 5/11

11:00 pm-7:35 pm

2 stops23h 35m

San Francisco

Mon 6/8

7:00 am-6:55 am

2 stops20h 55m

$541

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 3/20

5:21 am-11:40 pm

1 stop22h 19m

San Francisco

Wed 4/29

1:23 am-11:26 pm

1 stop19h 03m

$543

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 5/13

2:30 pm-11:55 pm

2 stops36h 25m

San Francisco

Sat 5/30

11:55 pm-4:15 am

2 stops25h 20m

$549

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $570.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $648 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $569 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 29% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of January 2026, prices for Santiago to San Francisco flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Fastest flight time

15h 23m

Direct flights

None
The fastest flight from Santiago to San Francisco takes 15h 23m
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5935.3 mi. 15h 23m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $408Free CancellationRating
6.6
2,491 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.2
11,189 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $508Free CancellationRating
7.5
1,912 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $511Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
DeltaPriceFrom $551Free CancellationRating
7.9
8,113 reviews
Search Delta flights
United AirlinesPriceFrom $571Free CancellationRating
7.4
9,198 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Santa Clara
Berkeley
Walnut Creek
Fremont
Daly City
Half Moon Bay
Salinas
Vallejo
Livermore
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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