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Cheap flights from Santiago to San Francisco from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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American Airlines Logo
11:15 pm - 11:19 amSCL-SFO
17h 04m1 stop
American Airlines Logo
8:02 am - 8:55 amSFO-SCL
19h 53m1 stop
$503American Airlines
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Wed, Dec 3 - Wed, Dec 10
American Airlines Logo
11:15 pm - 1:20 pmSCL-SFO
19h 05m1 stop
American Airlines Logo
1:17 pm - 8:55 amSFO-SCL
14h 38m1 stop
$505American Airlines
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Wed, Nov 26 - Wed, Dec 3
Avianca Logo
7:25 am - 11:40 pmSCL-SFO
20h 15m2 stops
Avianca Logo
2:20 pm - 3:20 pmSFO-SCL
21h 00m2 stops
$512Avianca
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Tue, Mar 10 - Mon, Mar 23
Avianca Logo
7:25 am - 11:40 pmSCL-SFO
20h 15m2 stops
Avianca Logo
2:20 pm - 3:20 pmSFO-SCL
21h 00m2 stops
$513Avianca
Find Deal
Tue, Mar 10 - Mon, Mar 23
Copa Airlines Logo
5:12 am - 11:17 pmSCL-SFO
23h 05m1 stop
Copa Airlines Logo
12:36 am - 3:43 amSFO-SCL
22h 07m1 stop
$532Copa Airlines
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Wed, Nov 26 - Tue, Dec 2
LATAM Airlines Logo
11:55 pm - 12:01 pmSCL-SFO
16h 06m1 stop
LATAM Airlines Logo
6:00 am - 7:00 amSFO-SCL
21h 00m1 stop
$533LATAM Airlines
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Tue, Mar 10 - Mon, Mar 23
Delta Logo
8:50 am - 11:37 pmSCL-SFO
19h 47m2 stops
Delta Logo
8:00 am - 7:40 amSFO-SCL
18h 40m1 stop
$534Delta
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Thu, Jan 29 - Mon, Feb 2
Delta Logo
11:10 pm - 8:56 pmSCL-SFO
26h 46m1 stop
Delta Logo
11:40 am - 3:30 pmSFO-SCL
22h 50m2 stops
$535Delta
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Tue, Nov 18 - Tue, Jan 27
LATAM Airlines Logo
8:50 pm - 3:13 pmSCL-SFO
22h 23m2 stops
LATAM Airlines Logo
6:00 am - 7:00 amSFO-SCL
21h 00m2 stops
$549LATAM Airlines
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Thu, Mar 19 - Mon, Mar 23
Copa Airlines Logo
3:23 am - 11:17 pmSCL-SFO
24h 54m1 stop
Copa Airlines Logo
1:54 am - 12:34 amSFO-SCL
18h 40m1 stop
$567Copa Airlines
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Sat, Dec 13 - Sun, Mar 22

United Airlines flights from Santiago to San Francisco

Our best United Airlines deals on Santiago to San Francisco flight tickets
United Airlines
Dec 18
SCL10:45 pmSantiago Arturo Merino Benitez
23h 07m
1 stop
SFO4:52 pmSan Francisco
Jan 5
SFO9:01 amSan Francisco
18h 49m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
$536
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United Airlines
Nov 10
SCL10:45 pmSantiago Arturo Merino Benitez
29h 14m
1 stop
SFO10:59 pmSan Francisco
Nov 17
SFO9:10 amSan Francisco
18h 40m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
$554
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United Airlines
Dec 19
SCL10:45 pmSantiago Arturo Merino Benitez
27h 26m
1 stop
SFO9:11 pmSan Francisco
Jan 4
SFO11:59 pmSan Francisco
27h 51m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
$576
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LATAM Airlines flights from Santiago to San Francisco

Our best LATAM Airlines deals on Santiago to San Francisco flight tickets
LATAM Airlines
Mar 10
SCL11:55 pmSantiago Arturo Merino Benitez
16h 06m
1 stop
SFO12:01 pmSan Francisco
Mar 23
SFO6:00 amSan Francisco
21h 00m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$533
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LATAM Airlines
Mar 19
SCL8:50 pmSantiago Arturo Merino Benitez
22h 23m
2 stops
SFO3:13 pmSan Francisco
Mar 23
SFO6:00 amSan Francisco
21h 00m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
$549
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LATAM Airlines
Apr 21
SCL4:00 pmSantiago Arturo Merino Benitez
30h 35m
2 stops
SFO7:35 pmSan Francisco
May 4
SFO6:00 amSan Francisco
22h 00m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$563
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momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 12/3

11:15 pm-11:19 am

1 stop17h 04m

San Francisco

Wed 12/10

8:02 am-8:55 am

1 stop19h 53m

$503

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 11/26

11:15 pm-1:20 pm

1 stop19h 05m

San Francisco

Wed 12/3

1:17 pm-8:55 am

1 stop14h 38m

$505

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 3/10

7:25 am-11:40 pm

2 stops20h 15m

San Francisco

Mon 3/23

2:20 pm-3:20 pm

2 stops21h 00m

$512

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 3/10

7:25 am-11:40 pm

2 stops20h 15m

San Francisco

Mon 3/23

2:20 pm-3:20 pm

2 stops21h 00m

$513

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 11/26

5:12 am-11:17 pm

1 stop23h 05m

San Francisco

Tue 12/2

12:36 am-3:43 am

1 stop22h 07m

$532

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 3/10

11:55 pm-12:01 pm

1 stop16h 06m

San Francisco

Mon 3/23

6:00 am-7:00 am

1 stop21h 00m

$533

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 1/29

8:50 am-11:37 pm

2 stops19h 47m

San Francisco

Mon 2/2

8:00 am-7:40 am

1 stop18h 40m

$534

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 11/18

11:10 pm-8:56 pm

1 stop26h 46m

San Francisco

Tue 1/27

11:40 am-3:30 pm

2 stops22h 50m

$535

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 3/19

8:50 pm-3:13 pm

2 stops22h 23m

San Francisco

Mon 3/23

6:00 am-7:00 am

2 stops21h 00m

$549

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sat 12/13

3:23 am-11:17 pm

1 stop24h 54m

San Francisco

Sun 3/22

1:54 am-12:34 am

1 stop18h 40m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $570.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Santiago to San Francisco is on a Saturday when prices can be found for as low as $663. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $834.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Santiago to San Francisco flights are usually those with departure times in the afternoon. Our users have found flights to San Francisco in the afternoon for as low as $565. Flights in the evening are often more expensive with an average ticket price of $822.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $673 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $581 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 32% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of November 2025, prices for Santiago to San Francisco flights are approximately 11% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Direct flights

None
There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.
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  • How far is Santiago Arturo Merino Benitez to San Francisco by plane?

    A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5935.3 mi. 15h 57m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Francisco?

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $408Free CancellationRating
6.6
2,469 reviews
Search Avianca flights
American AirlinesPriceFrom $481Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $511Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $518Free CancellationRating
7.5
1,874 reviews
Search LATAM Airlines flights
DeltaPriceFrom $547Free CancellationRating
7.9
8,001 reviews
Search Delta flights
United AirlinesPriceFrom $603Free CancellationRating
7.4
9,003 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Calistoga
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Vallejo
Walnut Creek
Half Moon Bay
Salinas
Livermore
Turlock
South San Francisco

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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