Which airport is the most popular layover for flights between Santiago and San Francisco?

Houston (IAH) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to San Francisco?

LATAM Airlines, American Airlines and Delta are the top three most popular airlines that fly to San Francisco from Santiago according to our data. LATAM Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Santiago to San Francisco?

Flights connecting via Los Angeles (LAX) have the shortest average one-way travel time: 14h 24m.

Which layover airport offers the lowest fares from Santiago to San Francisco?

Flights via Houston (IAH) offer the lowest average round-trip price of $710.

Which layover airport has the shortest connection time from Santiago to San Francisco?

Houston (IAH) has the shortest average layover time for this route: 2h 03m.

When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.

How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

There are 6 operators available for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport as of October 2026.

How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$425 Cheap Flights from Santiago to San Francisco in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to San Francisco

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:40 am - 10:35 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl

11:55 pm - 11:20 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

20h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$824Avianca

Tue, Apr 6 - Fri, Apr 30

6:40 am - 10:35 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl

2:15 pm - 2:15 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

21h 00m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$824Avianca

Fri, Apr 9 - Sat, Apr 24

9:55 pm - 11:04 amSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 09m2 stops Lima J Chavez Intl Los Angeles

7:00 am - 5:20 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

17h 20m2 stops Los Angeles Lima J Chavez Intl

$829LATAM Airlines

Thu, Feb 18 - Thu, Mar 4

6:40 am - 11:11 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 31m2 stops Lima J Chavez Intl Los Angeles

8:55 am - 5:35 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

17h 40m1 stop Los Angeles

$829LATAM Airlines

Fri, Apr 9 - Sat, Apr 24

9:55 pm - 1:29 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

20h 34m2 stops Lima J Chavez Intl Los Angeles

7:30 am - 7:40 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

19h 10m1 stop Atlanta Hartsfield-Jackson

$846Delta

Tue, Feb 2 - Wed, Feb 17

11:10 pm - 12:45 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

18h 35m1 stop Atlanta Hartsfield-Jackson

7:30 am - 7:40 amSFO San Francisco-SCL Santiago Arturo Merino Benitez

19h 10m1 stop Atlanta Hartsfield-Jackson

$846Delta

Wed, Feb 10 - Wed, Feb 17

9:55 pm - 3:40 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

22h 45m1 stop Toronto Pearson Intl

8:40 am - 12:15 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

22h 35m1 stop Toronto Pearson Intl

$866Air Canada

Thu, Dec 3 - Wed, Jan 13

12:20 pm - 5:25 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

34h 05m1 stop Panama City Tocumen Intl

7:36 pm - 11:35 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

22h 59m1 stop Panama City Tocumen Intl

$870Copa Airlines

Mon, Dec 7 - Sun, Dec 13

9:55 pm - 1:10 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

20h 15m1 stop Toronto Pearson Intl

6:30 am - 12:15 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

24h 45m2 stops Vancouver Intl Toronto Pearson Intl

$874Air Canada

Thu, Dec 24 - Mon, Jan 11

2:10 am - 6:28 pmSCL Santiago Arturo Merino Benitez-SFO San Francisco

19h 18m1 stop Panama City Tocumen Intl

7:55 pm - 1:52 pmSFO San Francisco-SCL Santiago Arturo Merino Benitez

14h 57m1 stop Panama City Tocumen Intl

$883Copa Airlines

Thu, Apr 8 - Fri, Apr 23

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Air Canada flights from Santiago to San Francisco

Our best Air Canada deals on Santiago to San Francisco flight tickets

Air Canada

Dec 3

SCL9:55 pmSantiago Arturo Merino Benitez

22h 45m

1 stop

SFO3:40 pmSan Francisco

Jan 13

SFO8:40 amSan Francisco

22h 35m

1 stop

SCL12:15 pmSantiago Arturo Merino Benitez

$866

Air Canada

Dec 24

SCL9:55 pmSantiago Arturo Merino Benitez

22h 45m

1 stop

SFO3:40 pmSan Francisco

Jan 13

SFO12:00 pmSan Francisco

19h 15m

1 stop

SCL12:15 pmSantiago Arturo Merino Benitez

$874

Air Canada

Dec 24

SCL9:55 pmSantiago Arturo Merino Benitez

28h 35m

1 stop

SFO9:30 pmSan Francisco

Jan 9

SFO8:25 amSan Francisco

46h 50m

2 stops

SCL12:15 pmSantiago Arturo Merino Benitez

$877

American Airlines flights from Santiago to San Francisco

Our best American Airlines deals on Santiago to San Francisco flight tickets

American Airlines

Feb 1

SCL10:15 pmSantiago Arturo Merino Benitez

18h 00m

1 stop

SFO11:15 amSan Francisco

Feb 28

SFO12:40 amSan Francisco

26h 05m

1 stop

SCL7:45 amSantiago Arturo Merino Benitez

$897

American Airlines

Feb 1

SCL11:45 pmSantiago Arturo Merino Benitez

18h 50m

2 stops

SFO1:35 pmSan Francisco

Mar 1

SFO8:00 amSan Francisco

20h 00m

1 stop

SCL9:00 amSantiago Arturo Merino Benitez

$903

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 4/6

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Fri 4/30

11:55 pm-11:20 pm

2 stops20h 25m

$824

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 4/9

6:40 am-10:35 pm

2 stops18h 55m

San Francisco

Sat 4/24

2:15 pm-2:15 pm

2 stops21h 00m

$824

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 2/18

9:55 pm-11:04 am

2 stops18h 09m

San Francisco

Thu 3/4

7:00 am-5:20 am

2 stops17h 20m

$829

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Fri 4/9

6:40 am-11:11 pm

2 stops19h 31m

San Francisco

Sat 4/24

8:55 am-5:35 am

1 stop17h 40m

$829

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Tue 2/2

9:55 pm-1:29 pm

2 stops20h 34m

San Francisco

Wed 2/17

7:30 am-7:40 am

1 stop19h 10m

$846

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Wed 2/10

11:10 pm-12:45 pm

1 stop18h 35m

San Francisco

Wed 2/17

7:30 am-7:40 am

1 stop19h 10m

$846

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/3

9:55 pm-3:40 pm

1 stop22h 45m

San Francisco

Wed 1/13

8:40 am-12:15 pm

1 stop22h 35m

$866

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Mon 12/7

12:20 pm-5:25 pm

1 stop34h 05m

San Francisco

Sun 12/13

7:36 pm-11:35 pm

1 stop22h 59m

$870

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 12/24

9:55 pm-1:10 pm

1 stop20h 15m

San Francisco

Mon 1/11

6:30 am-12:15 pm

2 stops24h 45m

$874

Quickest round-trip

SantiagoSan Francisco

SCL Santiago Arturo Merino Benitez - SFO San Francisco

SCLSFO

Santiago Arturo Merino Benitez

Thu 4/8

2:10 am-6:28 pm

1 stop19h 18m

San Francisco

Fri 4/23

7:55 pm-1:52 pm

1 stop14h 57m

$883

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santiago to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Santiago and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $640 to $1,020.
The lowest price recently found on this route was $824.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $640.

How far in advance should I book a flight from Santiago to San Francisco?

You are more likely to see cheaper flights to San Francisco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $717 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santiago for as low as $640 on momondo.

Can stopping save me money on Santiago to San Francisco flights?

You could potentially save up to 2% on your flight if you consider stops on a Santiago to San Francisco flight.

How have Santiago to San Francisco flight prices changed over time?

As of October 2026, prices for Santiago to San Francisco flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Francisco

Best Price Found	$425
Fastest flight time	16h 05m
Direct flights	None

The best one-way flight to San Francisco from Santiago in the past 72 hours is $425. The best round-trip flight deal from Santiago to San Francisco found on momondo in the last 72 hours is $824.

The fastest flight from Santiago to San Francisco takes 16h 05m

There are no direct flights from Santiago to San Francisco. There are no popular flight routes from Santiago to San Francisco.

Search flight deals

Frequently asked questions about flying from Santiago to San Francisco

How far is Santiago Arturo Merino Benitez to San Francisco by plane?
A flight from Santiago Arturo Merino Benitez to San Francisco will travel around 5934.4 mi. 16h 05m is a normal flight duration for this route.
When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
Prices for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport refresh daily.
How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
There are 6 operators available for flights from Santiago Arturo Merino Benitez Airport to San Francisco Airport as of October 2026.
How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Santiago to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Santiago to San Francisco is LATAM Airlines, representing 30% of all bookings. The subsequent popular airlines are American Airlines at 18%, Delta at 18%, and Copa Airlines at 16%.

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $311	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $494	Free Cancellation	Rating 7.4 1,970 reviews	Search LATAM Airlines flights
American Airlines	PriceFrom $515	Free Cancellation	Rating 7.0 12,188 reviews	Search American Airlines flights
Delta	PriceFrom $531	Free Cancellation	Rating 7.8 8,665 reviews	Search Delta flights
Avianca	PriceFrom $542	Free Cancellation	Rating 6.5 2,552 reviews	Search Avianca flights
United Airlines	PriceFrom $571	Free Cancellation	Rating 7.3 10,405 reviews	Search United Airlines flights

Santa Cruz

Carmel-by-the-Sea

Modesto

South San Francisco

Hayward

Bodega Bay

Walnut Creek

Santa Clara

Fremont

Berkeley

Sunnyvale

Half Moon Bay

Vallejo

Roseville

Salinas

Sonoma

Milpitas

Daly City

Palo Alto

Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to San Francisco with flexible booking policies on momondo?

All flight searches from Santiago to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to San Francisco?

Once you have performed a search for Santiago to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Santiago to San Francisco from $425

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Francisco departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Air Canada flights from Santiago to San Francisco

Our best Air Canada deals on Santiago to San Francisco flight tickets

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Our best American Airlines deals on Santiago to San Francisco flight tickets

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How to get the cheapest flight ticket from Santiago to San Francisco

What is the typical price of a round-trip flight between Santiago and San Francisco?

What is the cheapest month to fly to San Francisco?

How far in advance should I book a flight from Santiago to San Francisco?

Can stopping save me money on Santiago to San Francisco flights?

How have Santiago to San Francisco flight prices changed over time?

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Santiago and San Francisco?

Which layover airport offers the lowest fares from Santiago to San Francisco?

Which layover airport has the shortest travel time from Santiago to San Francisco?

Which layover airport has the shortest connection time from Santiago to San Francisco?

When to book flights from Santiago to San Francisco

Cheap Santiago to San Francisco (SCL to SFO) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Santiago to San Francisco

Best airlines flying from Santiago to San Francisco

Compare and see reviews for airlines that fly from Santiago to San Francisco with momondo

Traveling to a place near San Francisco?

Why use momondo?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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List of cabin classes available on flights landing in San Francisco. Availability may vary depending on flight origin and airline.

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