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Cheap flights from Santiago to San Diego from $297

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Diego departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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LATAM Airlines Logo
11:55 pm - 2:54 pm
SCL
-
SAN
18h 59m
1 stop
LATAM Airlines Logo
6:20 am - 5:35 am
SAN
-
SCL
19h 15m
1 stop
$597LATAM Airlines
Thu, Mar 12 - Mon, Mar 23
LATAM Airlines Logo
11:55 pm - 2:54 pm
SCL
-
SAN
18h 59m
1 stop
LATAM Airlines Logo
8:00 am - 6:45 am
SAN
-
SCL
18h 45m
2 stops
$609LATAM Airlines
Thu, Mar 12 - Mon, Mar 23
United Airlines Logo
9:45 pm - 12:57 pm
SCL
-
SAN
19h 12m
2 stops
United Airlines Logo
6:30 am - 7:50 am
SAN
-
SCL
21h 20m
2 stops
$613United Airlines
Thu, Mar 12 - Mon, Mar 23
Copa Airlines Logo
2:30 am - 6:30 pm
SCL
-
SAN
19h 00m
1 stop
Copa Airlines Logo
9:18 pm - 11:26 pm
SAN
-
SCL
23h 08m
1 stop
$624Copa Airlines
Sun, Apr 12 - Fri, Apr 24
Delta Logo
11:00 pm - 6:39 pm
SCL
-
SAN
22h 39m
2 stops
Delta Logo
11:02 am - 7:15 am
SAN
-
SCL
17h 13m
1 stop
$627Delta
Mon, Apr 13 - Fri, Apr 24
LATAM Airlines Logo
11:55 pm - 6:50 pm
SCL
-
SAN
22h 55m
1 stop
LATAM Airlines Logo
6:20 am - 5:35 am
SAN
-
SCL
19h 15m
1 stop
$636LATAM Airlines
Thu, Mar 12 - Mon, Mar 23
American Airlines Logo
11:15 pm - 2:18 pm
SCL
-
SAN
20h 03m
1 stop
American Airlines Logo
9:00 am - 7:00 am
SAN
-
SCL
18h 00m
1 stop
$637American Airlines
Mon, Mar 2 - Sun, Mar 8
LATAM Airlines Logo
11:55 pm - 2:54 pm
SCL
-
SAN
18h 59m
1 stop
LATAM Airlines Logo
6:20 am - 5:35 am
SAN
-
SCL
19h 15m
1 stop
$638LATAM Airlines
Thu, Mar 12 - Mon, Mar 23
American Airlines Logo
11:55 pm - 4:00 pm
SCL
-
SAN
21h 05m
2 stops
American Airlines Logo
1:01 pm - 9:05 am
SAN
-
SCL
16h 04m
1 stop
$642American Airlines
Mon, Mar 2 - Sun, Mar 8
United Airlines Logo
10:45 pm - 6:33 pm
SCL
-
SAN
24h 48m
1 stop
United Airlines Logo
12:16 pm - 7:50 am
SAN
-
SCL
15h 34m
1 stop
$645United Airlines
Fri, Mar 6 - Mon, Mar 9

LATAM Airlines flights from Santiago to San Diego

Our best LATAM Airlines deals on Santiago to San Diego flight tickets
LATAM Airlines
Mar 12
SCL11:55 pmSantiago Arturo Merino Benitez
18h 59m
1 stop
SAN2:54 pmSan Diego
Mar 23
SAN6:20 amSan Diego
19h 15m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$597
LATAM Airlines
Mar 12
SCL11:55 pmSantiago Arturo Merino Benitez
18h 59m
1 stop
SAN2:54 pmSan Diego
Mar 23
SAN8:00 amSan Diego
18h 45m
2 stops
SCL6:45 amSantiago Arturo Merino Benitez
$609
LATAM Airlines
Mar 12
SCL11:55 pmSantiago Arturo Merino Benitez
22h 55m
1 stop
SAN6:50 pmSan Diego
Mar 23
SAN6:20 amSan Diego
19h 15m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$636

United Airlines flights from Santiago to San Diego

Our best United Airlines deals on Santiago to San Diego flight tickets
United Airlines
Mar 12
SCL9:45 pmSantiago Arturo Merino Benitez
19h 12m
2 stops
SAN12:57 pmSan Diego
Mar 23
SAN6:30 amSan Diego
21h 20m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez
$613
United Airlines
Mar 6
SCL10:45 pmSantiago Arturo Merino Benitez
24h 48m
1 stop
SAN6:33 pmSan Diego
Mar 9
SAN12:16 pmSan Diego
15h 34m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
$645
United Airlines
Mar 6
SCL10:45 pmSantiago Arturo Merino Benitez
24h 48m
1 stop
SAN6:33 pmSan Diego
Mar 9
SAN6:15 amSan Diego
21h 35m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez
$650

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/12

11:55 pm-2:54 pm

1 stop18h 59m

San Diego

Mon 3/23

6:20 am-5:35 am

1 stop19h 15m

$597

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/12

11:55 pm-2:54 pm

1 stop18h 59m

San Diego

Mon 3/23

8:00 am-6:45 am

2 stops18h 45m

$609

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/12

9:45 pm-12:57 pm

2 stops19h 12m

San Diego

Mon 3/23

6:30 am-7:50 am

2 stops21h 20m

$613

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sun 4/12

2:30 am-6:30 pm

1 stop19h 00m

San Diego

Fri 4/24

9:18 pm-11:26 pm

1 stop23h 08m

$624

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 4/13

11:00 pm-6:39 pm

2 stops22h 39m

San Diego

Fri 4/24

11:02 am-7:15 am

1 stop17h 13m

$627

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/12

11:55 pm-6:50 pm

1 stop22h 55m

San Diego

Mon 3/23

6:20 am-5:35 am

1 stop19h 15m

$636

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 3/2

11:15 pm-2:18 pm

1 stop20h 03m

San Diego

Sun 3/8

9:00 am-7:00 am

1 stop18h 00m

$637

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/12

11:55 pm-2:54 pm

1 stop18h 59m

San Diego

Mon 3/23

6:20 am-5:35 am

1 stop19h 15m

$638

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 3/2

11:55 pm-4:00 pm

2 stops21h 05m

San Diego

Sun 3/8

1:01 pm-9:05 am

1 stop16h 04m

$642

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 3/6

10:45 pm-6:33 pm

1 stop24h 48m

San Diego

Mon 3/9

12:16 pm-7:50 am

1 stop15h 34m

$645

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Santiago during the month October is also very affordable. Most momondo users find prices during this month for around $542.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $805 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $614 on momondo.

Can stopping save me money on Santiago to San Diego flights?

You could potentially save up to 27% on your flight if you consider stops on a Santiago to San Diego flight.

How have Santiago to San Diego flight prices changed over time?

As of January 2026, prices for Santiago to San Diego flights are approximately 6% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Fastest flight time

16h 49m

Direct flights

None
The fastest flight from Santiago to San Diego takes 16h 49m
There are no direct flights from Santiago to San Diego. There are no popular flight routes from Santiago to San Diego.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 16h 49m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Diego?

Best airlines flying from Santiago to San Diego

Compare and see reviews for airlines that fly from Santiago to San Diego with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $497Free CancellationRating
7.5
1,913 reviews
Search LATAM Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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