Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Santiago to San Diego from $399

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Diego departing on 5/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Santiago to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
11:25 pm - 3:09 pm
SCL
-
SAN
18h 44m
1 stop
LATAM Airlines Logo
10:00 am - 5:35 am
SAN
-
SCL
16h 35m
1 stop
$570LATAM Airlines
Mon, Aug 3 - Mon, Aug 17
LATAM Airlines Logo
8:40 pm - 7:35 pm
SCL
-
SAN
25h 55m
1 stop
LATAM Airlines Logo
10:00 am - 5:35 am
SAN
-
SCL
16h 35m
1 stop
$592LATAM Airlines
Mon, Aug 3 - Mon, Aug 17
LATAM Airlines Logo
11:25 pm - 7:18 pm
SCL
-
SAN
22h 53m
1 stop
LATAM Airlines Logo
10:00 am - 5:35 am
SAN
-
SCL
16h 35m
1 stop
$594LATAM Airlines
Mon, Aug 3 - Mon, Aug 17
LATAM Airlines Logo
11:25 pm - 10:27 am
SCL
-
SAN
14h 02m
1 stop
LATAM Airlines Logo
6:15 am - 5:35 am
SAN
-
SCL
20h 20m
1 stop
$600LATAM Airlines
Mon, Aug 24 - Sun, Aug 30
LATAM Airlines Logo
11:25 pm - 6:54 pm
SCL
-
SAN
22h 29m
1 stop
LATAM Airlines Logo
10:40 pm - 7:45 pm
SAN
-
SCL
18h 05m
2 stops
$603LATAM Airlines
Mon, Aug 24 - Sun, Aug 30
Copa Airlines Logo
4:14 am - 6:30 pm
SCL
-
SAN
17h 16m
1 stop
Copa Airlines Logo
8:58 pm - 11:26 pm
SAN
-
SCL
23h 28m
1 stop
$605Copa Airlines
Mon, Aug 24 - Sun, Aug 30
LATAM Airlines Logo
8:40 pm - 11:16 am
SCL
-
SAN
17h 36m
1 stop
LATAM Airlines Logo
6:15 am - 5:35 am
SAN
-
SCL
20h 20m
1 stop
$608LATAM Airlines
Fri, May 22 - Sun, Jun 7
Copa Airlines Logo
4:09 am - 6:30 pm
SCL
-
SAN
17h 21m
1 stop
Copa Airlines Logo
10:00 pm - 10:43 pm
SAN
-
SCL
21h 43m
1 stop
$609Copa Airlines
Fri, May 29 - Sun, Jun 14
LATAM Airlines Logo
11:25 pm - 2:57 pm
SCL
-
SAN
18h 32m
1 stop
LATAM Airlines Logo
10:50 am - 5:35 am
SAN
-
SCL
15h 45m
1 stop
$610LATAM Airlines
Wed, Jun 3 - Wed, Jun 10
Delta Logo
8:40 pm - 12:38 pm
SCL
-
SAN
18h 58m
1 stop
Delta Logo
6:15 am - 6:55 am
SAN
-
SCL
21h 40m
2 stops
$612Delta
Fri, May 29 - Mon, Jun 15

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Copa Airlines flights from Santiago to San Diego

Our best Copa Airlines deals on Santiago to San Diego flight tickets
Copa Airlines
Aug 24
SCL4:14 amSantiago Arturo Merino Benitez
17h 16m
1 stop
SAN6:30 pmSan Diego
Aug 30
SAN8:58 pmSan Diego
23h 28m
1 stop
SCL11:26 pmSantiago Arturo Merino Benitez
$605
Copa Airlines
May 29
SCL4:09 amSantiago Arturo Merino Benitez
17h 21m
1 stop
SAN6:30 pmSan Diego
Jun 14
SAN10:00 pmSan Diego
21h 43m
1 stop
SCL10:43 pmSantiago Arturo Merino Benitez
$609
Copa Airlines
May 21
SCL12:38 amSantiago Arturo Merino Benitez
20h 52m
1 stop
SAN6:30 pmSan Diego
Jun 7
SAN10:00 pmSan Diego
18h 23m
1 stop
SCL7:23 pmSantiago Arturo Merino Benitez
$635

LATAM Airlines flights from Santiago to San Diego

Our best LATAM Airlines deals on Santiago to San Diego flight tickets
LATAM Airlines
Aug 3
SCL11:25 pmSantiago Arturo Merino Benitez
18h 44m
1 stop
SAN3:09 pmSan Diego
Aug 17
SAN10:00 amSan Diego
16h 35m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$570
LATAM Airlines
Aug 3
SCL8:40 pmSantiago Arturo Merino Benitez
25h 55m
1 stop
SAN7:35 pmSan Diego
Aug 17
SAN10:00 amSan Diego
16h 35m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$592
LATAM Airlines
Aug 3
SCL11:25 pmSantiago Arturo Merino Benitez
22h 53m
1 stop
SAN7:18 pmSan Diego
Aug 17
SAN10:00 amSan Diego
16h 35m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$594

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/3

11:25 pm-3:09 pm

1 stop18h 44m

San Diego

Mon 8/17

10:00 am-5:35 am

1 stop16h 35m

$570

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/3

8:40 pm-7:35 pm

1 stop25h 55m

San Diego

Mon 8/17

10:00 am-5:35 am

1 stop16h 35m

$592

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/3

11:25 pm-7:18 pm

1 stop22h 53m

San Diego

Mon 8/17

10:00 am-5:35 am

1 stop16h 35m

$594

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/24

11:25 pm-10:27 am

1 stop14h 02m

San Diego

Sun 8/30

6:15 am-5:35 am

1 stop20h 20m

$600

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/24

11:25 pm-6:54 pm

1 stop22h 29m

San Diego

Sun 8/30

10:40 pm-7:45 pm

2 stops18h 05m

$603

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/24

4:14 am-6:30 pm

1 stop17h 16m

San Diego

Sun 8/30

8:58 pm-11:26 pm

1 stop23h 28m

$605

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 5/22

8:40 pm-11:16 am

1 stop17h 36m

San Diego

Sun 6/7

6:15 am-5:35 am

1 stop20h 20m

$608

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 5/29

4:09 am-6:30 pm

1 stop17h 21m

San Diego

Sun 6/14

10:00 pm-10:43 pm

1 stop21h 43m

$609
Quickest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 6/3

11:25 pm-2:57 pm

1 stop18h 32m

San Diego

Wed 6/10

10:50 am-5:35 am

1 stop15h 45m

$610

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 5/29

8:40 pm-12:38 pm

1 stop18h 58m

San Diego

Mon 6/15

6:15 am-6:55 am

2 stops21h 40m

$612

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Santiago during the month October is also very affordable. Most momondo users find prices during this month for around $533.

How far in advance should I book a flight from Santiago to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $752 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $521 on momondo.

How have Santiago to San Diego flight prices changed over time?

As of April 2026, prices for Santiago to San Diego flights are approximately 17% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Fastest flight time

17h 16m

Direct flights

None
The fastest flight from Santiago to San Diego takes 17h 16m
There are no direct flights from Santiago to San Diego. There are no popular flight routes from Santiago to San Diego.
Search flight deals

Frequently asked questions about flying from Santiago to San Diego

  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 17h 16m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 5/24
Sun 5/31
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States