Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santiago to San Diego from $295

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Diego departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santiago to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
11:35 pm - 9:15 amSCL-SAN
14h 40m1 stop
LATAM Airlines Logo
9:59 am - 6:00 amSAN-SCL
15h 01m1 stop
$492LATAM Airlines
Find Deal
Fri, Nov 21 - Sat, Nov 29
LATAM Airlines Logo
11:35 pm - 5:56 pmSCL-SAN
23h 21m1 stop
LATAM Airlines Logo
6:35 am - 6:00 amSAN-SCL
18h 25m1 stop
$494LATAM Airlines
Find Deal
Fri, Nov 21 - Sat, Nov 29
Copa Airlines Logo
3:23 am - 5:03 pmSCL-SAN
18h 40m1 stop
Copa Airlines Logo
8:12 pm - 12:24 amSAN-SCL
23h 12m1 stop
$502Copa Airlines
Find Deal
Thu, Nov 20 - Wed, Dec 3
United Airlines Logo
10:45 pm - 1:04 pmSCL-SAN
19h 19m2 stops
United Airlines Logo
6:30 am - 8:50 amSAN-SCL
21h 20m2 stops
$503United Airlines
Find Deal
Wed, Nov 26 - Tue, Dec 2
United Airlines Logo
10:45 pm - 6:24 pmSCL-SAN
24h 39m1 stop
United Airlines Logo
9:10 pm - 8:50 amSAN-SCL
30h 40m2 stops
$505United Airlines
Find Deal
Sat, Nov 22 - Sun, Nov 30
American Airlines Logo
11:15 pm - 3:07 pmSCL-SAN
20h 52m1 stop
American Airlines Logo
6:15 am - 7:45 amSAN-SCL
20h 30m1 stop
$514American Airlines
Find Deal
Mon, Dec 1 - Mon, Dec 8
American Airlines Logo
11:15 pm - 3:19 pmSCL-SAN
21h 04m2 stops
American Airlines Logo
6:15 am - 8:00 amSAN-SCL
20h 45m1 stop
$517American Airlines
Find Deal
Fri, Nov 21 - Sat, Nov 29
Copa Airlines Logo
3:23 am - 5:03 pmSCL-SAN
18h 40m1 stop
Copa Airlines Logo
8:10 pm - 12:06 amSAN-SCL
22h 56m1 stop
$532Copa Airlines
Find Deal
Sat, Nov 8 - Mon, Nov 24
Delta Logo
10:55 pm - 6:00 pmSCL-SAN
23h 05m2 stops
Delta Logo
6:24 am - 7:40 amSAN-SCL
20h 16m1 stop
$535Delta
Find Deal
Fri, Oct 31 - Thu, Nov 13
Delta Logo
8:15 am - 9:20 amSCL-SAN
29h 05m2 stops
Delta Logo
7:48 pm - 6:30 amSAN-SCL
29h 42m1 stop
$555Delta
Find Deal
Wed, Oct 29 - Sun, Nov 2

LATAM Airlines flights from Santiago to San Diego

Our best LATAM Airlines deals on Santiago to San Diego flight tickets
LATAM Airlines
Nov 21
SCL11:35 pmSantiago Arturo Merino Benitez
14h 40m
1 stop
SAN9:15 amSan Diego
Nov 29
SAN9:59 amSan Diego
15h 01m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
$492
Find similar
LATAM Airlines
Nov 21
SCL11:35 pmSantiago Arturo Merino Benitez
23h 21m
1 stop
SAN5:56 pmSan Diego
Nov 29
SAN6:35 amSan Diego
18h 25m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
$494
Find similar
LATAM Airlines
Nov 21
SCL11:35 pmSantiago Arturo Merino Benitez
14h 40m
1 stop
SAN9:15 amSan Diego
Dec 3
SAN9:59 amSan Diego
14h 36m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$495
Find similar

Copa Airlines flights from Santiago to San Diego

Our best Copa Airlines deals on Santiago to San Diego flight tickets
Copa Airlines
Nov 20
SCL3:23 amSantiago Arturo Merino Benitez
18h 40m
1 stop
SAN5:03 pmSan Diego
Dec 3
SAN8:12 pmSan Diego
23h 12m
1 stop
SCL12:24 amSantiago Arturo Merino Benitez
$502
Find similar
Copa Airlines
Nov 8
SCL3:23 amSantiago Arturo Merino Benitez
18h 40m
1 stop
SAN5:03 pmSan Diego
Nov 24
SAN8:10 pmSan Diego
22h 56m
1 stop
SCL12:06 amSantiago Arturo Merino Benitez
$532
Find similar
Copa Airlines
Dec 9
SCL3:23 amSantiago Arturo Merino Benitez
19h 14m
1 stop
SAN5:37 pmSan Diego
Jan 6
SAN8:16 pmSan Diego
19h 04m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
$577
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 11/21

11:35 pm-9:15 am

1 stop14h 40m

San Diego

Sat 11/29

9:59 am-6:00 am

1 stop15h 01m

$492

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 11/21

11:35 pm-5:56 pm

1 stop23h 21m

San Diego

Sat 11/29

6:35 am-6:00 am

1 stop18h 25m

$494

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 11/20

3:23 am-5:03 pm

1 stop18h 40m

San Diego

Wed 12/3

8:12 pm-12:24 am

1 stop23h 12m

$502

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 11/26

10:45 pm-1:04 pm

2 stops19h 19m

San Diego

Tue 12/2

6:30 am-8:50 am

2 stops21h 20m

$503

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/22

10:45 pm-6:24 pm

1 stop24h 39m

San Diego

Sun 11/30

9:10 pm-8:50 am

2 stops30h 40m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 12/1

11:15 pm-3:07 pm

1 stop20h 52m

San Diego

Mon 12/8

6:15 am-7:45 am

1 stop20h 30m

$514

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 11/21

11:15 pm-3:19 pm

2 stops21h 04m

San Diego

Sat 11/29

6:15 am-8:00 am

1 stop20h 45m

$517

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/8

3:23 am-5:03 pm

1 stop18h 40m

San Diego

Mon 11/24

8:10 pm-12:06 am

1 stop22h 56m

$532

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 10/31

10:55 pm-6:00 pm

2 stops23h 05m

San Diego

Thu 11/13

6:24 am-7:40 am

1 stop20h 16m

$535

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/29

8:15 am-9:20 am

2 stops29h 05m

San Diego

Sun 11/2

7:48 pm-6:30 am

1 stop29h 42m

$555

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Santiago during the month October is also very affordable. Most momondo users find prices during this month for around $542.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Santiago to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $825. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $1,573. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $835 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $568 on momondo.

How have Santiago to San Diego flight prices changed over time?

As of October 2025, prices for Santiago to San Diego flights are approximately 15% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Direct flights

None
There are no direct flights from Santiago to San Diego. There are no popular flight routes from Santiago to San Diego.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 14h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Diego?

Best airlines flying from Santiago to San Diego

Compare and see reviews for airlines that fly from Santiago to San Diego with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $497Free CancellationRating
7.5
1,866 reviews
Search LATAM Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
Poway
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 11/15
Sat 11/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States