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Cheap flights from Santiago to San Diego from $343

1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
11:55 pm - 7:14 pmSCL  Santiago Arturo Merino Benitez-SAN San Diego
23h 19m1 stop Los Angeles
LATAM Airlines Logo
12:38 pm - 7:40 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
15h 02m1 stop Atlanta Hartsfield-Jackson
$651LATAM Airlines
Wed, Oct 21 - Mon, Oct 26
Copa Airlines Logo
3:28 am - 6:27 pmSCL  Santiago Arturo Merino Benitez-SAN San Diego
18h 59m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:30 pm - 2:48 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
23h 18m1 stop Panama City Tocumen Intl
$653Copa Airlines
Tue, Oct 27 - Sun, Nov 8
Delta Logo
11:10 pm - 4:25 pmSCL  Santiago Arturo Merino Benitez-SAN San Diego
21h 15m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:25 pm - 5:35 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
26h 10m2 stops Atlanta Hartsfield-Jackson Miami
$656Delta
Wed, Oct 28 - Sun, Nov 8
United Airlines Logo
9:45 pm - 11:31 amSCL  Santiago Arturo Merino Benitez-SAN San Diego
17h 46m2 stops Houston George Bush Intcntl Los Angeles
United Airlines Logo
7:41 pm - 8:50 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
32h 09m2 stops San Francisco Houston George Bush Intcntl
$657United Airlines
Wed, Oct 28 - Sun, Nov 8
United Airlines Logo
9:45 pm - 11:31 amSCL  Santiago Arturo Merino Benitez-SAN San Diego
17h 46m2 stops Houston George Bush Intcntl Los Angeles
United Airlines Logo
7:41 pm - 8:50 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
32h 09m2 stops San Francisco Houston George Bush Intcntl
$658United Airlines
Wed, Oct 28 - Sun, Nov 8
United Airlines Logo
9:45 pm - 11:31 amSCL  Santiago Arturo Merino Benitez-SAN San Diego
17h 46m2 stops Houston George Bush Intcntl Los Angeles
United Airlines Logo
7:41 pm - 8:50 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
32h 09m2 stops San Francisco Houston George Bush Intcntl
$659United Airlines
Wed, Oct 28 - Sun, Nov 8
United Airlines Logo
9:45 pm - 11:31 amSCL  Santiago Arturo Merino Benitez-SAN San Diego
17h 46m2 stops Houston George Bush Intcntl Los Angeles
United Airlines Logo
7:41 pm - 8:50 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
32h 09m2 stops San Francisco Houston George Bush Intcntl
$660United Airlines
Wed, Oct 28 - Sun, Nov 8
LATAM Airlines Logo
11:55 pm - 3:10 pmSCL  Santiago Arturo Merino Benitez-SAN San Diego
20h 15m1 stop Los Angeles
LATAM Airlines Logo
6:15 am - 7:30 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
20h 15m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
$665LATAM Airlines
Sat, Nov 7 - Wed, Nov 11
LATAM Airlines Logo
7:10 pm - 7:26 pmSCL  Santiago Arturo Merino Benitez-SAN San Diego
28h 16m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
LATAM Airlines Logo
10:30 pm - 2:35 pmSAN  San Diego-SCL Santiago Arturo Merino Benitez
36h 05m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
$669LATAM Airlines
Thu, Sep 24 - Fri, Oct 2
LATAM Airlines Logo
11:55 pm - 10:10 amSCL  Santiago Arturo Merino Benitez-SAN San Diego
38h 15m2 stops Miami Los Angeles
LATAM Airlines Logo
10:30 pm - 5:35 amSAN  San Diego-SCL Santiago Arturo Merino Benitez
27h 05m2 stops Atlanta Hartsfield-Jackson Miami
$670LATAM Airlines
Sun, Sep 27 - Sun, Oct 4

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LATAM Airlines flights from Santiago to San Diego

Our best LATAM Airlines deals on Santiago to San Diego flight tickets
LATAM Airlines
Oct 21
SCL11:55 pmSantiago Arturo Merino Benitez
23h 19m
1 stop
SAN7:14 pmSan Diego
Oct 26
SAN12:38 pmSan Diego
15h 02m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
$651
LATAM Airlines
Nov 7
SCL11:55 pmSantiago Arturo Merino Benitez
20h 15m
1 stop
SAN3:10 pmSan Diego
Nov 11
SAN6:15 amSan Diego
20h 15m
2 stops
SCL7:30 amSantiago Arturo Merino Benitez
$665
LATAM Airlines
Sep 24
SCL7:10 pmSantiago Arturo Merino Benitez
28h 16m
2 stops
SAN7:26 pmSan Diego
Oct 2
SAN10:30 pmSan Diego
36h 05m
2 stops
SCL2:35 pmSantiago Arturo Merino Benitez
$669

United Airlines flights from Santiago to San Diego

Our best United Airlines deals on Santiago to San Diego flight tickets
United Airlines
Oct 28
SCL9:45 pmSantiago Arturo Merino Benitez
17h 46m
2 stops
SAN11:31 amSan Diego
Nov 8
SAN7:41 pmSan Diego
32h 09m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
$657
United Airlines
Oct 28
SCL9:45 pmSantiago Arturo Merino Benitez
17h 46m
2 stops
SAN11:31 amSan Diego
Nov 8
SAN7:41 pmSan Diego
32h 09m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
$658
United Airlines
Oct 28
SCL9:45 pmSantiago Arturo Merino Benitez
17h 46m
2 stops
SAN11:31 amSan Diego
Nov 8
SAN7:41 pmSan Diego
32h 09m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
$659

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

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Route

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Price

Cheapest round-trip
Quickest round-trip

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/21

11:55 pm-7:14 pm

1 stop23h 19m

San Diego

Mon 10/26

12:38 pm-7:40 am

1 stop15h 02m

$651

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Tue 10/27

3:28 am-6:27 pm

1 stop18h 59m

San Diego

Sun 11/8

10:30 pm-2:48 am

1 stop23h 18m

$653

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/28

11:10 pm-4:25 pm

1 stop21h 15m

San Diego

Sun 11/8

10:25 pm-5:35 am

2 stops26h 10m

$656

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/28

9:45 pm-11:31 am

2 stops17h 46m

San Diego

Sun 11/8

7:41 pm-8:50 am

2 stops32h 09m

$657

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/28

9:45 pm-11:31 am

2 stops17h 46m

San Diego

Sun 11/8

7:41 pm-8:50 am

2 stops32h 09m

$658

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/28

9:45 pm-11:31 am

2 stops17h 46m

San Diego

Sun 11/8

7:41 pm-8:50 am

2 stops32h 09m

$659

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/28

9:45 pm-11:31 am

2 stops17h 46m

San Diego

Sun 11/8

7:41 pm-8:50 am

2 stops32h 09m

$660

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/7

11:55 pm-3:10 pm

1 stop20h 15m

San Diego

Wed 11/11

6:15 am-7:30 am

2 stops20h 15m

$665

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Thu 9/24

7:10 pm-7:26 pm

2 stops28h 16m

San Diego

Fri 10/2

10:30 pm-2:35 pm

2 stops36h 05m

$669

SantiagoSan Diego

SCL Santiago Arturo Merino Benitez - SAN San Diego

SCLSAN

Santiago Arturo Merino Benitez

Sun 9/27

11:55 pm-10:10 am

2 stops38h 15m

San Diego

Sun 10/4

10:30 pm-5:35 am

2 stops27h 05m

$670

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $653 to $809.
The lowest price recently found on this route was $651.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Santiago during the month December is also very affordable. Most momondo users find prices during this month for around $656.

How far in advance should I book a flight from Santiago to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $747 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $650 on momondo.

Can stopping save me money on Santiago to San Diego flights?

You could potentially save up to 36% on your flight if you consider stops on a Santiago to San Diego flight.

How have Santiago to San Diego flight prices changed over time?

As of September 2026, prices for Santiago to San Diego flights are approximately 17% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Best Price Found

$343

Fastest flight time

17h 08m

Direct flights

None
The best one-way flight to San Diego from Santiago in the past 72 hours is $343. The best round-trip flight deal from Santiago to San Diego found on momondo in the last 72 hours is $651.
The fastest flight from Santiago to San Diego takes 17h 08m
There are no direct flights from Santiago to San Diego. There are no popular flight routes from Santiago to San Diego.
Search flight deals

Frequently asked questions about flying from Santiago to San Diego

  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 17h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
El Cajon
Coronado
National City
La Mesa
Julian
Poway
San Ysidro
Imperial Beach
Santee
Alpine
Lemon Grove
Borrego Springs

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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