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Cheap flights from Santiago to San Diego from $404

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Diego departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
12:46 am - 6:30 pm
SCL
-
SAN
20h 44m
1 stop
Copa Airlines Logo
9:18 pm - 7:23 pm
SAN
-
SCL
19h 05m
1 stop
$609Copa Airlines
Tue, Apr 14 - Wed, Apr 29
Delta Logo
10:55 pm - 8:45 pm
SCL
-
SAN
24h 50m
1 stop
Delta Logo
9:45 pm - 7:15 am
SAN
-
SCL
30h 30m
1 stop
$612Delta
Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
11:00 pm - 6:39 pm
SCL
-
SAN
22h 39m
2 stops
LATAM Airlines Logo
6:20 am - 10:04 am
SAN
-
SCL
24h 44m
3 stops
$620LATAM Airlines
Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
6:05 pm - 6:39 pm
SCL
-
SAN
27h 34m
2 stops
LATAM Airlines Logo
2:10 pm - 2:05 pm
SAN
-
SCL
20h 55m
2 stops
$621LATAM Airlines
Thu, Apr 23 - Mon, Apr 27
LATAM Airlines Logo
10:30 am - 1:00 pm
SCL
-
SAN
29h 30m
2 stops
LATAM Airlines Logo
6:15 am - 1:35 pm
SAN
-
SCL
28h 20m
2 stops
$626LATAM Airlines
Wed, Apr 15 - Wed, Apr 29
Copa Airlines Logo
5:49 am - 6:30 pm
SCL
-
SAN
16h 41m
1 stop
Copa Airlines Logo
9:18 pm - 10:43 pm
SAN
-
SCL
22h 25m
1 stop
$629Copa Airlines
Fri, Apr 3 - Sun, Apr 19
LATAM Airlines Logo
4:30 pm - 11:25 pm
SCL
-
SAN
33h 55m
2 stops
LATAM Airlines Logo
6:20 am - 7:15 am
SAN
-
SCL
21h 55m
2 stops
$639LATAM Airlines
Wed, Apr 15 - Wed, Apr 29
LATAM Airlines Logo
6:45 pm - 2:50 pm
SCL
-
SAN
23h 05m
2 stops
LATAM Airlines Logo
6:20 am - 5:45 am
SAN
-
SCL
20h 25m
2 stops
$671LATAM Airlines
Thu, Apr 23 - Mon, Apr 27
LATAM Airlines Logo
7:15 am - 9:49 am
SCL
-
SAN
29h 34m
2 stops
LATAM Airlines Logo
11:02 am - 5:25 pm
SAN
-
SCL
27h 23m
2 stops
$672LATAM Airlines
Wed, Apr 15 - Wed, Apr 29
LATAM Airlines Logo
8:40 pm - 9:49 am
SCL
-
SAN
16h 09m
1 stop
LATAM Airlines Logo
6:15 am - 5:35 am
SAN
-
SCL
20h 20m
1 stop
$673LATAM Airlines
Fri, Apr 24 - Sun, May 10

LATAM Airlines flights from Santiago to San Diego

Our best LATAM Airlines deals on Santiago to San Diego flight tickets
LATAM Airlines
Apr 21
SCL11:00 pmSantiago Arturo Merino Benitez
22h 39m
2 stops
SAN6:39 pmSan Diego
Apr 28
SAN6:20 amSan Diego
24h 44m
3 stops
SCL10:04 amSantiago Arturo Merino Benitez
$620
LATAM Airlines
Apr 23
SCL6:05 pmSantiago Arturo Merino Benitez
27h 34m
2 stops
SAN6:39 pmSan Diego
Apr 27
SAN2:10 pmSan Diego
20h 55m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
$621
LATAM Airlines
Apr 15
SCL10:30 amSantiago Arturo Merino Benitez
29h 30m
2 stops
SAN1:00 pmSan Diego
Apr 29
SAN6:15 amSan Diego
28h 20m
2 stops
SCL1:35 pmSantiago Arturo Merino Benitez
$626

United Airlines flights from Santiago to San Diego

Our best United Airlines deals on Santiago to San Diego flight tickets
United Airlines
Mar 12
SCL9:45 pmSantiago Arturo Merino Benitez
18h 59m
2 stops
SAN12:44 pmSan Diego
Mar 23
SAN6:15 amSan Diego
21h 35m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez
$860
United Airlines
Mar 12
SCL9:45 pmSantiago Arturo Merino Benitez
21h 04m
2 stops
SAN2:49 pmSan Diego
Mar 23
SAN6:30 amSan Diego
21h 20m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez
$864
United Airlines
Mar 12
SCL9:45 pmSantiago Arturo Merino Benitez
22h 53m
1 stop
SAN4:38 pmSan Diego
Mar 23
SAN1:53 pmSan Diego
13h 57m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
$869

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 4/14

12:46 am-6:30 pm

1 stop20h 44m

San Diego

Wed 4/29

9:18 pm-7:23 pm

1 stop19h 05m

$609

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 4/21

10:55 pm-8:45 pm

1 stop24h 50m

San Diego

Tue 4/28

9:45 pm-7:15 am

1 stop30h 30m

$612

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 4/21

11:00 pm-6:39 pm

2 stops22h 39m

San Diego

Tue 4/28

6:20 am-10:04 am

3 stops24h 44m

$620

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 4/23

6:05 pm-6:39 pm

2 stops27h 34m

San Diego

Mon 4/27

2:10 pm-2:05 pm

2 stops20h 55m

$621

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 4/15

10:30 am-1:00 pm

2 stops29h 30m

San Diego

Wed 4/29

6:15 am-1:35 pm

2 stops28h 20m

$626

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 4/3

5:49 am-6:30 pm

1 stop16h 41m

San Diego

Sun 4/19

9:18 pm-10:43 pm

1 stop22h 25m

$629

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 4/15

4:30 pm-11:25 pm

2 stops33h 55m

San Diego

Wed 4/29

6:20 am-7:15 am

2 stops21h 55m

$639

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 4/23

6:45 pm-2:50 pm

2 stops23h 05m

San Diego

Mon 4/27

6:20 am-5:45 am

2 stops20h 25m

$671

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 4/15

7:15 am-9:49 am

2 stops29h 34m

San Diego

Wed 4/29

11:02 am-5:25 pm

2 stops27h 23m

$672
Quickest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 4/24

8:40 pm-9:49 am

1 stop16h 09m

San Diego

Sun 5/10

6:15 am-5:35 am

1 stop20h 20m

$673

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Santiago during the month October is also very affordable. Most momondo users find prices during this month for around $535.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $786 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $521 on momondo.

Can stopping save me money on Santiago to San Diego flights?

You could potentially save up to 32% on your flight if you consider stops on a Santiago to San Diego flight.

How have Santiago to San Diego flight prices changed over time?

As of March 2026, prices for Santiago to San Diego flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Fastest flight time

16h 41m

Direct flights

None
The fastest flight from Santiago to San Diego takes 16h 41m
There are no direct flights from Santiago to San Diego. There are no popular flight routes from Santiago to San Diego.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 16h 41m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Diego?

Best airlines flying from Santiago to San Diego

Compare and see reviews for airlines that fly from Santiago to San Diego with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $497Free CancellationRating
7.4
1,918 reviews
Search LATAM Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
Imperial Beach
La Mesa
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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