Cheap flights from Santiago to San Diego from $284

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Diego departing on 11/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Santiago to San Diego

Cheap round-trip flights

LATAM Airlines Logo
11:05 pm - 7:06 pmSCL-SAN
24h 01m1 stop
LATAM Airlines Logo
6:20 am - 6:00 amSAN-SCL
19h 40m1 stop
$494LATAM Airlines
Find Deal
Mon, Sep 29 - Mon, Oct 6
LATAM Airlines Logo
11:05 pm - 7:06 pmSCL-SAN
24h 01m1 stop
LATAM Airlines Logo
12:00 pm - 7:40 amSAN-SCL
15h 40m1 stop
$498LATAM Airlines
Find Deal
Tue, Sep 30 - Thu, Oct 30
United Airlines Logo
9:45 pm - 4:25 pmSCL-SAN
22h 40m1 stop
United Airlines Logo
1:47 pm - 8:50 amSAN-SCL
14h 03m1 stop
$505United Airlines
Find Deal
Fri, Oct 31 - Thu, Nov 13
Delta Logo
11:30 pm - 6:00 pmSCL-SAN
22h 30m2 stops
Delta Logo
6:20 am - 7:00 amSAN-SCL
19h 40m1 stop
$506Delta
Find Deal
Wed, Sep 24 - Sun, Nov 9
United Airlines Logo
9:45 pm - 4:25 pmSCL-SAN
22h 40m1 stop
United Airlines Logo
8:00 am - 8:50 amSAN-SCL
19h 50m1 stop
$515United Airlines
Find Deal
Wed, Oct 29 - Sun, Nov 2
Copa Airlines Logo
3:26 am - 5:50 pmSCL-SAN
18h 24m1 stop
Copa Airlines Logo
9:12 pm - 12:04 amSAN-SCL
22h 52m1 stop
$518Copa Airlines
Find Deal
Sun, Sep 28 - Mon, Oct 6
Copa Airlines Logo
1:13 am - 5:50 pmSCL-SAN
20h 37m1 stop
Copa Airlines Logo
9:12 pm - 8:20 pmSAN-SCL
19h 08m1 stop
$534Copa Airlines
Find Deal
Tue, Sep 23 - Wed, Oct 8
Delta Logo
11:55 pm - 9:19 amSCL-SAN
14h 24m1 stop
Delta Logo
6:20 am - 7:00 amSAN-SCL
19h 40m2 stops
$641Delta
Find Deal
Wed, Nov 26 - Tue, Dec 2
American Airlines Logo
10:15 pm - 2:37 pmSCL-SAN
21h 22m2 stops
American Airlines Logo
10:28 am - 7:50 amSAN-SCL
16h 22m2 stops
$653American Airlines
Find Deal
Fri, Nov 21 - Wed, Dec 3
American Airlines Logo
10:15 pm - 12:45 pmSCL-SAN
19h 30m2 stops
American Airlines Logo
10:28 am - 9:05 amSAN-SCL
17h 37m2 stops
$662American Airlines
Find Deal
Fri, Nov 21 - Wed, Dec 3

United Airlines flights from Santiago to San Diego

Our best United Airlines deals on Santiago to San Diego flight tickets
United Airlines
Oct 31
SCL9:45 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
SAN4:25 pmSan Diego
Nov 13
SAN1:47 pmSan Diego
14h 03m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
United Airlines
Oct 29
SCL9:45 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
SAN4:25 pmSan Diego
Nov 2
SAN8:00 amSan Diego
19h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
United Airlines
Oct 29
SCL9:45 pmSantiago Arturo Merino Benitez
21h 15m
2 stops
SAN3:00 pmSan Diego
Nov 2
SAN5:15 amSan Diego
21h 35m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez

Copa Airlines flights from Santiago to San Diego

Our best Copa Airlines deals on Santiago to San Diego flight tickets
Copa Airlines
Sep 28
SCL3:26 amSantiago Arturo Merino Benitez
18h 24m
1 stop
SAN5:50 pmSan Diego
Oct 6
SAN9:12 pmSan Diego
22h 52m
1 stop
SCL12:04 amSantiago Arturo Merino Benitez
Copa Airlines
Aug 24
SCL4:11 amSantiago Arturo Merino Benitez
16h 33m
1 stop
SAN5:44 pmSan Diego
Sep 5
SAN9:08 pmSan Diego
22h 32m
1 stop
SCL10:40 pmSantiago Arturo Merino Benitez
Copa Airlines
Aug 23
SCL12:13 amSantiago Arturo Merino Benitez
20h 31m
1 stop
SAN5:44 pmSan Diego
Sep 5
SAN9:08 pmSan Diego
19h 12m
1 stop
SCL7:20 pmSantiago Arturo Merino Benitez

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 9/29

11:05 pm-7:06 pm

1 stop24h 01m

San Diego

Mon 10/6

6:20 am-6:00 am

1 stop19h 40m

$494

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 9/30

11:05 pm-7:06 pm

1 stop24h 01m

San Diego

Thu 10/30

12:00 pm-7:40 am

1 stop15h 40m

$498

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 10/31

9:45 pm-4:25 pm

1 stop22h 40m

San Diego

Thu 11/13

1:47 pm-8:50 am

1 stop14h 03m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 9/24

11:30 pm-6:00 pm

2 stops22h 30m

San Diego

Sun 11/9

6:20 am-7:00 am

1 stop19h 40m

$506

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 10/29

9:45 pm-4:25 pm

1 stop22h 40m

San Diego

Sun 11/2

8:00 am-8:50 am

1 stop19h 50m

$515

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sun 9/28

3:26 am-5:50 pm

1 stop18h 24m

San Diego

Mon 10/6

9:12 pm-12:04 am

1 stop22h 52m

$518

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 9/23

1:13 am-5:50 pm

1 stop20h 37m

San Diego

Wed 10/8

9:12 pm-8:20 pm

1 stop19h 08m

$534

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 11/26

11:55 pm-9:19 am

1 stop14h 24m

San Diego

Tue 12/2

6:20 am-7:00 am

2 stops19h 40m

$641

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 11/21

10:15 pm-2:37 pm

2 stops21h 22m

San Diego

Wed 12/3

10:28 am-7:50 am

2 stops16h 22m

$653

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 11/21

10:15 pm-12:45 pm

2 stops19h 30m

San Diego

Wed 12/3

10:28 am-9:05 am

2 stops17h 37m

$662

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Santiago during the month November is also very affordable. Most momondo users find prices during this month for around $764.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Santiago to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $825. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $1,573. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $888 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $642 on momondo.

How have Santiago to San Diego flight prices changed over time?

As of August 2025, prices for Santiago to San Diego flights are approximately 44% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Best Price Found

$284

Fastest flight time

14h 14m

Direct flights

None

Airports in San Diego

1 airport
The best one-way flight to San Diego from Santiago in the past 72 hours is $284. The best round-trip flight deal from Santiago to San Diego found on momondo in the last 72 hours is $494.
The fastest flight from Santiago to San Diego takes 14h 14m
There are no direct flights from Santiago to San Diego. Popular non-direct route for this connection is Santiago Arturo Merino Benitez Airport - San Diego Airport.
There is 1 airport near San Diego: San Diego (SAN)
  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 14h 14m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Diego?

Best airlines flying from Santiago to San Diego

Compare and see reviews for airlines that fly from Santiago to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $702Free CancellationRating
8.0
7,985 reviews
Search Delta flights
LATAM AirlinesPriceFrom $803Free CancellationRating
7.5
1,840 reviews
Search LATAM Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
Poway
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 8/21
Thu 8/28

Find better results for your trip to the United States