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Cheap flights from Santiago to San Diego from $314

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to San Diego departing on 3/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
5:21 am - 5:14 pm
SCL
-
SAN
16h 53m1 stop
Copa Airlines Logo
9:18 pm - 8:20 pm
SAN
-
SCL
19h 02m1 stop
$625Copa Airlines
lun., mar. 2 - dom., mar. 8
Delta Logo
11:25 pm - 6:51 pm
SCL
-
SAN
23h 26m2 stops
Delta Logo
10:30 pm - 5:35 am
SAN
-
SCL
27h 05m2 stops
$628Delta
jue., mar. 12 - mar., mar. 24
LATAM Airlines Logo
11:55 pm - 7:12 pm
SCL
-
SAN
23h 17m1 stop
LATAM Airlines Logo
6:21 am - 5:35 am
SAN
-
SCL
19h 14m1 stop
$637LATAM Airlines
jue., mar. 19 - lun., mar. 23
Copa Airlines Logo
2:34 am - 6:30 pm
SCL
-
SAN
18h 56m1 stop
Copa Airlines Logo
9:16 pm - 11:26 pm
SAN
-
SCL
23h 10m1 stop
$639Copa Airlines
dom., abr. 5 - vie., abr. 17
LATAM Airlines Logo
11:55 pm - 7:12 pm
SCL
-
SAN
23h 17m1 stop
LATAM Airlines Logo
2:05 pm - 5:35 am
SAN
-
SCL
35h 30m2 stops
$643LATAM Airlines
sáb., mar. 21 - sáb., mar. 28
LATAM Airlines Logo
11:55 pm - 2:52 pm
SCL
-
SAN
18h 57m1 stop
LATAM Airlines Logo
2:05 pm - 5:35 am
SAN
-
SCL
35h 30m2 stops
$647LATAM Airlines
vie., mar. 20 - sáb., mar. 28
American Airlines Logo
11:15 pm - 9:56 pm
SCL
-
SAN
27h 41m1 stop
American Airlines Logo
7:10 am - 8:15 am
SAN
-
SCL
20h 05m1 stop
$652American Airlines
vie., dic. 19 - vie., ene. 23
Delta Logo
11:10 pm - 11:28 pm
SCL
-
SAN
29h 18m1 stop
Delta Logo
6:30 am - 6:10 am
SAN
-
SCL
18h 40m1 stop
$655Delta
vie., dic. 19 - vie., ene. 23
United Airlines Logo
10:45 pm - 5:34 pm
SCL
-
SAN
23h 49m2 stops
United Airlines Logo
7:45 am - 8:50 am
SAN
-
SCL
20h 05m2 stops
$656United Airlines
vie., dic. 19 - vie., ene. 23
United Airlines Logo
10:45 pm - 3:01 pm
SCL
-
SAN
21h 16m2 stops
United Airlines Logo
12:11 pm - 8:50 am
SAN
-
SCL
15h 39m1 stop
$657United Airlines
vie., dic. 19 - vie., ene. 23

LATAM Airlines flights from Santiago to San Diego

Our best LATAM Airlines deals on Santiago to San Diego flight tickets
LATAM Airlines
Mar 19
SCL11:55 pmSantiago Arturo Merino Benitez
23h 17m
1 stop
SAN7:12 pmSan Diego
Mar 23
SAN6:21 amSan Diego
19h 14m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
$637
Find similar
LATAM Airlines
Mar 21
SCL11:55 pmSantiago Arturo Merino Benitez
23h 17m
1 stop
SAN7:12 pmSan Diego
Mar 28
SAN2:05 pmSan Diego
35h 30m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
$643
Find similar
LATAM Airlines
Mar 20
SCL11:55 pmSantiago Arturo Merino Benitez
18h 57m
1 stop
SAN2:52 pmSan Diego
Mar 28
SAN2:05 pmSan Diego
35h 30m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
$647
Find similar

Copa Airlines flights from Santiago to San Diego

Our best Copa Airlines deals on Santiago to San Diego flight tickets
Copa Airlines
Mar 2
SCL5:21 amSantiago Arturo Merino Benitez
16h 53m
1 stop
SAN5:14 pmSan Diego
Mar 8
SAN9:18 pmSan Diego
19h 02m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
$625
Find similar
Copa Airlines
Apr 5
SCL2:34 amSantiago Arturo Merino Benitez
18h 56m
1 stop
SAN6:30 pmSan Diego
Apr 17
SAN9:16 pmSan Diego
23h 10m
1 stop
SCL11:26 pmSantiago Arturo Merino Benitez
$639
Find similar
Copa Airlines
Dec 10
SCL5:44 amSantiago Arturo Merino Benitez
16h 53m
1 stop
SAN5:37 pmSan Diego
Jan 6
SAN8:16 pmSan Diego
22h 27m
1 stop
SCL11:43 pmSantiago Arturo Merino Benitez
$652
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 4, 2025.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

lun. 3/2

5:21 am-5:14 pm

1 stop16h 53m

San Diego

dom. 3/8

9:18 pm-8:20 pm

1 stop19h 02m

$625

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

jue. 3/12

11:25 pm-6:51 pm

2 stops23h 26m

San Diego

mar. 3/24

10:30 pm-5:35 am

2 stops27h 05m

$628

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

jue. 3/19

11:55 pm-7:12 pm

1 stop23h 17m

San Diego

lun. 3/23

6:21 am-5:35 am

1 stop19h 14m

$637

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

dom. 4/5

2:34 am-6:30 pm

1 stop18h 56m

San Diego

vie. 4/17

9:16 pm-11:26 pm

1 stop23h 10m

$639

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

sáb. 3/21

11:55 pm-7:12 pm

1 stop23h 17m

San Diego

sáb. 3/28

2:05 pm-5:35 am

2 stops35h 30m

$643

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

vie. 3/20

11:55 pm-2:52 pm

1 stop18h 57m

San Diego

sáb. 3/28

2:05 pm-5:35 am

2 stops35h 30m

$647

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

vie. 12/19

11:15 pm-9:56 pm

1 stop27h 41m

San Diego

vie. 1/23

7:10 am-8:15 am

1 stop20h 05m

$652

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

vie. 12/19

11:10 pm-11:28 pm

1 stop29h 18m

San Diego

vie. 1/23

6:30 am-6:10 am

1 stop18h 40m

$655

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

vie. 12/19

10:45 pm-5:34 pm

2 stops23h 49m

San Diego

vie. 1/23

7:45 am-8:50 am

2 stops20h 05m

$656

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

vie. 12/19

10:45 pm-3:01 pm

2 stops21h 16m

San Diego

vie. 1/23

12:11 pm-8:50 am

1 stop15h 39m

$657

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Santiago to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Santiago during the month October is also very affordable. Most momondo users find prices during this month for around $531.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Santiago to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $825. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $1,573. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $806 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Santiago for as low as $642 on momondo.

Can stopping save me money on Santiago to San Diego flights?

You could potentially save up to 12% on your flight if you consider stops on a Santiago to San Diego flight.

How have Santiago to San Diego flight prices changed over time?

As of December 2025, prices for Santiago to San Diego flights are approximately 36% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to San Diego (SCL to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to San Diego

Fastest flight time

16h 46m

Direct flights

None
The fastest flight from Santiago to San Diego takes 16h 46m
There are no direct flights from Santiago to San Diego. There are no popular flight routes from Santiago to San Diego.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to San Diego by plane?

    San Diego is 5476.6 mi away from Santiago Arturo Merino Benitez. Flights usually cover this in 16h 46m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to San Diego Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to San Diego?

Best airlines flying from Santiago to San Diego

Compare and see reviews for airlines that fly from Santiago to San Diego with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $497Free CancellationRating
7.5
1,890 reviews
Search LATAM Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
Poway
La Mesa
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to San Diego?

momondo helps you find the best flight between Santiago and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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