Cheap flights from Santiago to Sao Paulo from $140

The cheapest month to fly to Sao Paulo from Santiago is in December. Flight prices, which tend to average around $109, are often lower during this time because this is during the off-season. If you don’t want to visit Sao Paulo in December, then you should wait until August to fly from Santiago, when ticket prices are also cheap, with an average price of $111.

The cheapest day to depart on your flight to Sao Paulo is on a Wednesday when prices can be found for as low as $637. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,039.

At noon is the cheapest time of day to fly from Santiago to Sao Paulo when you can find flight prices for as low as $435. Flying to Sao Paulo at noon is an ideal time because this is during off-peak travel hours. Flights to Sao Paulo are more costly in the morning, with an average ticket price of $1,078. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Santiago Arturo Merino Benitez to Sao Paulo Guarulhos Intl for the best Santiago Arturo Merino Benitez - Sao Paulo flight prices

You are more likely to see cheaper flights to Sao Paulo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Sao Paulo for around $254 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sao Paulo from Santiago for as low as $227 on momondo.

There are 3 cabin classes available to choose from on Santiago to Sao Paulo flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 4% on your flight if you consider stops on a Santiago to Sao Paulo flight.

As of May 2026, prices for Santiago to Sao Paulo flights are approximately 54% more expensive when compared to flights at the same time last year.

Historically, on average around 13% of flights between Santiago and Sao Paulo have experienced a delay on any given week. The average delay length over the past 12 months has been 126 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the least number of delays on this route over the last 12 months; with about 13% of their flights experiencing any sort of delay.

As of May 2026, 14 flights take off from Santiago and land in Sao Paulo each day. The most common flight departure time for this route is 7:00AM, with 40% of daily flights taking off at noon.

As of May 2026, there are 98 flights per week flying from Santiago to Sao Paulo. The most common day of the week flights depart is Wed, with 23% of flights taking off on this day.