Cheap flights from Santiago to Sao Paulo from $141

The cheapest month to fly to Sao Paulo from Santiago is in December. Flight prices, which tend to average around $109, are often lower during this time because this is during the off-season. If you don’t want to visit Sao Paulo in December, then you should wait until August to fly from Santiago, when ticket prices are also cheap, with an average price of $111.

The cheapest day to depart on your flight to Sao Paulo is on a Wednesday when prices can be found for as low as $842. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,139.

In the evening is the cheapest time of day to fly from Santiago to Sao Paulo when you can find flight prices for as low as $396. Flying to Sao Paulo in the evening is an ideal time because this is during off-peak travel hours. Flights to Sao Paulo are more costly in the morning, with an average ticket price of $1,139. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Santiago Arturo Merino Benitez to Sao Paulo Guarulhos Intl for the best Santiago Arturo Merino Benitez - Sao Paulo flight prices

You are more likely to see cheaper flights to Sao Paulo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Sao Paulo for around $251 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sao Paulo from Santiago for as low as $221 on momondo.

You could potentially save up to 1% on your flight if you consider stops on a Santiago to Sao Paulo flight.

As of April 2026, prices for Santiago to Sao Paulo flights are approximately 67% more expensive when compared to flights at the same time last year.

JetSMART, LATAM Airlines, and GOL are the most popular carriers operating from Santiago Arturo Merino Benitez to Sao Paulo

LATAM Airlines, Turkish Airlines and Sky Airline are the top three most popular airlines that fly to Sao Paulo from Santiago according to our data. LATAM Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Sao Paulo. Keep in mind that there are 3 different airlines that fly to Sao Paulo on a routine basis, so you have a few additional options to choose from.

Historically, on average around 12% of flights between Santiago and Sao Paulo have experienced a delay on any given week. The average delay length over the past 12 months has been 126 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the least number of delays on this route over the last 12 months; with about 12% of their flights experiencing any sort of delay.

As of April 2026, 8 flights take off from Santiago and land in Sao Paulo each day. The most common flight departure time for this route is 4:00PM, with 31% of daily flights taking off at noon.

As of April 2026, there are 58 flights per week flying from Santiago to Sao Paulo. The most common day of the week flights depart is Wed, with 38% of flights taking off on this day.