Cheap flights from Santa Ana to San Francisco from $81

If you aren’t able to travel to San Francisco during the month of May, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $171.

The cheapest day to depart from Santa Ana to San Francisco is on a Friday when prices can be found for as low as $203. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $356.

Our data shows that the cheapest Santa Ana to San Francisco flights are usually those with departure times in the afternoon. Our users have found flights to San Francisco in the afternoon for as low as $182. Flights in the evening are often more expensive with an average ticket price of $335.

Fly from Santa Ana J. Wayne/Orange Cnty to San Francisco for the best Santa Ana J. Wayne/Orange Cnty - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Santa Ana when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $225 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Santa Ana for as low as $170 on momondo.

There are 4 cabin classes available to choose from on Santa Ana J. Wayne/Orange Cnty to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Alaska Airlines, and Delta are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to San Francisco

United Airlines, Frontier and Southwest are the top three most popular airlines that fly to San Francisco from Santa Ana according to our data. United Airlines is the first choice among our users, with 27% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 10 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 16% of flights between Santa Ana and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 122 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 15% of their flights experiencing any sort of delay.

As of February 2026, 42 flights take off from Santa Ana and land in San Francisco each day. The most common flight departure time for this route is 10:00AM, with 44% of daily flights taking off at noon.

As of February 2026, 298 flights take off from Santa Ana and land in San Francisco each week. The most common flight departure day for this route is Thu, with 17% of weekly flights taking off on this day.