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Cheap flights from Panama to San Diego from $332

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to San Diego departing on 9/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama to San Diego

Recent round-trip flight deals from Panama to San Diego

Enter your travel dates to find the best prices.
Copa Airlines Logo
1:55 pm - 6:30 pm
PTY
-
SAN
6h 35mnonstop
Copa Airlines Logo
10:00 pm - 6:13 am
SAN
-
PTY
6h 13mnonstop
$601Copa Airlines
Fri, Sep 18 - Sun, Oct 18
United Airlines Logo
10:00 am - 9:24 pm
PTY
-
SAN
13h 24m
1 stop
United Airlines Logo
4:46 pm - 6:37 pm
SAN
-
PTY
23h 51m
1 stop
$607United Airlines
Fri, Sep 18 - Sun, Oct 18
American Airlines Logo
3:35 pm - 12:05 pm
PTY
-
SAN
22h 30m
2 stops
American Airlines Logo
10:45 pm - 2:00 pm
SAN
-
PTY
13h 15m
2 stops
$620American Airlines
Fri, Oct 23 - Wed, Oct 28
United Airlines Logo
10:00 am - 5:46 pm
PTY
-
SAN
9h 46m
1 stop
United Airlines Logo
8:00 am - 6:37 pm
SAN
-
PTY
8h 37m
1 stop
$626United Airlines
Fri, Sep 25 - Mon, Sep 28
United Airlines Logo
10:00 am - 5:46 pm
PTY
-
SAN
9h 46m
1 stop
United Airlines Logo
1:24 pm - 2:14 pm
SAN
-
PTY
22h 50m
2 stops
$631United Airlines
Fri, Sep 25 - Mon, Sep 28
American Airlines Logo
3:35 pm - 11:25 am
PTY
-
SAN
21h 50m
1 stop
American Airlines Logo
4:28 pm - 2:00 pm
SAN
-
PTY
19h 32m
2 stops
$636American Airlines
Fri, Oct 23 - Wed, Oct 28
United Airlines Logo
3:41 pm - 10:53 pm
PTY
-
SAN
33h 12m
1 stop
United Airlines Logo
11:00 am - 2:45 pm
SAN
-
PTY
24h 45m
2 stops
$690United Airlines
Sat, Oct 31 - Fri, Nov 6
Delta Logo
2:21 pm - 11:03 pm
PTY
-
SAN
10h 42m
1 stop
Delta Logo
10:40 pm - 1:56 pm
SAN
-
PTY
12h 16m
1 stop
$719Delta
Sat, Oct 31 - Fri, Nov 6
Copa Airlines Logo
2:01 pm - 6:30 pm
PTY
-
SAN
6h 29mnonstop
Copa Airlines Logo
10:00 pm - 6:17 am
SAN
-
PTY
6h 17mnonstop
$736Copa Airlines
Fri, Aug 7 - Mon, Sep 7
United Airlines Logo
7:55 am - 12:31 am
PTY
-
SAN
18h 36m
2 stops
United Airlines Logo
8:00 am - 6:37 pm
SAN
-
PTY
8h 37m
1 stop
$741United Airlines
Fri, Aug 7 - Mon, Sep 7

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Copa Airlines flights from Panama to San Diego

Our best Copa Airlines deals on Panama to San Diego flight tickets
Copa Airlines
Sep 18
PTY1:55 pmPanama City Tocumen Intl
6h 35m
SAN6:30 pmSan Diego
Oct 18
SAN10:00 pmSan Diego
6h 13m
PTY6:13 amPanama City Tocumen Intl
$601
Copa Airlines
Aug 7
PTY2:01 pmPanama City Tocumen Intl
6h 29m
SAN6:30 pmSan Diego
Sep 7
SAN10:00 pmSan Diego
6h 17m
PTY6:17 amPanama City Tocumen Intl
$736
Copa Airlines
Jul 22
PTY2:01 pmPanama City Tocumen Intl
6h 29m
SAN6:30 pmSan Diego
Jul 26
SAN10:00 pmSan Diego
6h 22m
PTY6:22 amPanama City Tocumen Intl
$787

United Airlines flights from Panama to San Diego

Our best United Airlines deals on Panama to San Diego flight tickets
United Airlines
Sep 18
PTY10:00 amPanama City Tocumen Intl
13h 24m
1 stop
SAN9:24 pmSan Diego
Oct 18
SAN4:46 pmSan Diego
23h 51m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$607
United Airlines
Sep 25
PTY10:00 amPanama City Tocumen Intl
9h 46m
1 stop
SAN5:46 pmSan Diego
Sep 28
SAN8:00 amSan Diego
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$626
United Airlines
Sep 25
PTY10:00 amPanama City Tocumen Intl
9h 46m
1 stop
SAN5:46 pmSan Diego
Sep 28
SAN1:24 pmSan Diego
22h 50m
2 stops
PTY2:14 pmPanama City Tocumen Intl
$631

momondo Fare Finder

 
Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Panama to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 9/18

1:55 pm-6:30 pm

Nonstop6h 35m

San Diego

Sun 10/18

10:00 pm-6:13 am

Nonstop6h 13m

$601

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 9/18

10:00 am-9:24 pm

1 stop13h 24m

San Diego

Sun 10/18

4:46 pm-6:37 pm

1 stop23h 51m

$607

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 10/23

3:35 pm-12:05 pm

2 stops22h 30m

San Diego

Wed 10/28

10:45 pm-2:00 pm

2 stops13h 15m

$620

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 9/25

10:00 am-5:46 pm

1 stop9h 46m

San Diego

Mon 9/28

8:00 am-6:37 pm

1 stop8h 37m

$626

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 9/25

10:00 am-5:46 pm

1 stop9h 46m

San Diego

Mon 9/28

1:24 pm-2:14 pm

2 stops22h 50m

$631

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 10/23

3:35 pm-11:25 am

1 stop21h 50m

San Diego

Wed 10/28

4:28 pm-2:00 pm

2 stops19h 32m

$636

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 10/31

3:41 pm-10:53 pm

1 stop33h 12m

San Diego

Fri 11/6

11:00 am-2:45 pm

2 stops24h 45m

$690

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 10/31

2:21 pm-11:03 pm

1 stop10h 42m

San Diego

Fri 11/6

10:40 pm-1:56 pm

1 stop12h 16m

$719
Quickest round-trip

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 8/7

2:01 pm-6:30 pm

Nonstop6h 29m

San Diego

Mon 9/7

10:00 pm-6:17 am

Nonstop6h 17m

$736

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 8/7

7:55 am-12:31 am

2 stops18h 36m

San Diego

Mon 9/7

8:00 am-6:37 pm

1 stop8h 37m

$741

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from Panama during the month November is also very affordable. Most momondo users find prices during this month for around $207.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Panama to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $334. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $714. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest Panama to San Diego flight route?

Fly from Panama City Tocumen Intl to San Diego for the best Panama - San Diego flight prices

What cabin class options are available on Panama to San Diego flights?

There are 2 cabin classes available to choose from on Panama to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama to San Diego flights?

You could potentially save up to 35% on your flight if you consider stops on a Panama to San Diego flight.

Cheap Panama to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to San Diego

Fastest flight time

6h 29m

Direct flights

Mon, Thu, Fri and Sat

Airports in San Diego

1 airport
The fastest flight from Panama to San Diego takes 6h 29m
Direct flights go from Panama to San Diego on Monday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There is 1 airport in San Diego. From Panama there are direct flights to San Diego (SAN).
Search flight deals

Frequently asked questions about flying from Panama to San Diego

  • When did momondo last update prices for flights from Panama to San Diego Airport?

    Prices for flights from Panama to San Diego Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama to San Diego Airport?

  • How old do you have to be to fly from Panama to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama to San Diego?

Best airlines flying from Panama to San Diego

Compare and see reviews for airlines that fly from Panama to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $297Free CancellationRating
7.6
1,567 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $361Free CancellationRating
7.4
9,858 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
Poway
La Mesa
San Ysidro
Borrego Springs
Imperial Beach
Lemon Grove
Santee
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Panama to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama to San Diego with flexible booking policies on momondo?

Flights from Panama to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama to San Diego?

Once all potential Panama to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to San Diego right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Diego from Panama. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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