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Cheap flights from Panama to San Diego from $329

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to San Diego departing on 1/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to San Diego

Recent round-trip flight deals from Panama to San Diego

Enter your travel dates to find the best prices.
United Airlines Logo
7:55 am - 7:57 pm
PTY
-
SAN
14h 02m1 stop
United Airlines Logo
5:42 pm - 6:37 pm
SAN
-
PTY
22h 55m1 stop
$648United Airlines
jue., may. 28 - dom., may. 31
Copa Airlines Logo
1:45 pm - 5:41 pm
PTY
-
SAN
6h 56mnonstop
Copa Airlines Logo
8:16 pm - 5:20 am
SAN
-
PTY
6h 04mnonstop
$707Copa Airlines
dom., ene. 25 - lun., ene. 26
United Airlines Logo
8:55 am - 9:56 pm
PTY
-
SAN
16h 01m1 stop
United Airlines Logo
8:37 pm - 2:45 pm
SAN
-
PTY
15h 08m2 stops
$713United Airlines
mar., ene. 20 - mar., ene. 27
United Airlines Logo
8:55 am - 9:56 pm
PTY
-
SAN
16h 01m1 stop
United Airlines Logo
8:00 am - 7:38 pm
SAN
-
PTY
8h 38m1 stop
$722United Airlines
vie., ene. 23 - mar., ene. 27
United Airlines Logo
8:55 am - 7:54 pm
PTY
-
SAN
13h 59m2 stops
United Airlines Logo
4:10 pm - 5:07 pm
SAN
-
PTY
21h 57m2 stops
$726United Airlines
vie., ene. 23 - mar., ene. 27
Multiple Airlines Logo
9:09 am - 12:59 pm
PTY
-
SAN
29h 50m1 stop
Multiple Airlines Logo
9:13 pm - 5:20 am
SAN
-
PTY
6h 07mnonstop
$798Multiple Airlines
jue., may. 28 - dom., may. 31
United Airlines Logo
4:41 pm - 10:46 am
PTY
-
SAN
21h 05m2 stops
United Airlines Logo
1:51 pm - 7:38 pm
SAN
-
PTY
26h 47m1 stop
$809United Airlines
mar., ene. 6 - lun., ene. 26
United Airlines Logo
8:55 am - 4:36 pm
PTY
-
SAN
10h 41m1 stop
United Airlines Logo
6:00 pm - 2:45 pm
SAN
-
PTY
17h 45m2 stops
$832United Airlines
mié., ene. 7 - sáb., ene. 24
Multiple Airlines Logo
10:26 am - 6:51 pm
PTY
-
SAN
11h 25m1 stop
Multiple Airlines Logo
11:03 am - 8:34 pm
SAN
-
PTY
30h 31m1 stop
$837Multiple Airlines
dom., ene. 25 - lun., ene. 26
Copa Airlines Logo
7:55 am - 7:54 pm
PTY
-
SAN
14h 59m1 stop
Copa Airlines Logo
8:16 pm - 5:20 am
SAN
-
PTY
6h 04mnonstop
$843Copa Airlines
dom., ene. 25 - lun., ene. 26

United Airlines flights from Panama to San Diego

Our best United Airlines deals on Panama to San Diego flight tickets
United Airlines
May 28
PTY7:55 amPanama City Tocumen Intl
14h 02m
1 stop
SAN7:57 pmSan Diego
May 31
SAN5:42 pmSan Diego
22h 55m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$648
Find similar
United Airlines
Jan 20
PTY8:55 amPanama City Tocumen Intl
12h 41m
1 stop
SAN6:36 pmSan Diego
Jan 27
SAN8:00 amSan Diego
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$713
Find similar
United Airlines
Jan 23
PTY8:55 amPanama City Tocumen Intl
16h 01m
1 stop
SAN9:56 pmSan Diego
Jan 27
SAN8:00 amSan Diego
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$722
Find similar

Copa Airlines flights from Panama to San Diego

Our best Copa Airlines deals on Panama to San Diego flight tickets
Copa Airlines
Jan 25
PTY1:45 pmPanama City Tocumen Intl
6h 56m
SAN5:41 pmSan Diego
Jan 26
SAN8:16 pmSan Diego
6h 04m
PTY5:20 amPanama City Tocumen Intl
$707
Find similar
Copa Airlines
Jan 25
PTY7:55 amPanama City Tocumen Intl
14h 59m
1 stop
SAN7:54 pmSan Diego
Jan 26
SAN8:16 pmSan Diego
6h 04m
PTY5:20 amPanama City Tocumen Intl
$843
Find similar
Copa Airlines
Dec 24
PTY1:45 pmPanama City Tocumen Intl
6h 52m
SAN5:37 pmSan Diego
Jan 5
SAN8:16 pmSan Diego
6h 04m
PTY5:20 amPanama City Tocumen Intl
$1,233
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 23, 2025.
Use the filters below to find and compare flights from Panama to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

jue. 5/28

7:55 am-7:57 pm

1 stop14h 02m

San Diego

dom. 5/31

5:42 pm-6:37 pm

1 stop22h 55m

$648

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 1/25

1:45 pm-5:41 pm

Nonstop6h 56m

San Diego

lun. 1/26

8:16 pm-5:20 am

Nonstop6h 04m

$707

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mar. 1/20

8:55 am-9:56 pm

1 stop16h 01m

San Diego

mar. 1/27

8:37 pm-2:45 pm

2 stops15h 08m

$713

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 1/23

8:55 am-9:56 pm

1 stop16h 01m

San Diego

mar. 1/27

8:00 am-7:38 pm

1 stop8h 38m

$722

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 1/23

8:55 am-7:54 pm

2 stops13h 59m

San Diego

mar. 1/27

4:10 pm-5:07 pm

2 stops21h 57m

$726

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

jue. 5/28

9:09 am-12:59 pm

1 stop29h 50m

San Diego

dom. 5/31

9:13 pm-5:20 am

Nonstop6h 07m

$798

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mar. 1/6

4:41 pm-10:46 am

2 stops21h 05m

San Diego

lun. 1/26

1:51 pm-7:38 pm

1 stop26h 47m

$809

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 1/7

8:55 am-4:36 pm

1 stop10h 41m

San Diego

sáb. 1/24

6:00 pm-2:45 pm

2 stops17h 45m

$832

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 1/25

10:26 am-6:51 pm

1 stop11h 25m

San Diego

lun. 1/26

11:03 am-8:34 pm

1 stop30h 31m

$837

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 1/25

7:55 am-7:54 pm

1 stop14h 59m

San Diego

lun. 1/26

8:16 pm-5:20 am

Nonstop6h 04m

$843

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Panama during the month November is also very affordable. Most momondo users find prices during this month for around $428.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Panama to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $235. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $668. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $334. Flights in the morning are often more expensive with an average ticket price of $697.

What is the cheapest Panama to San Diego flight route?

Fly from Panama City Tocumen Intl to San Diego for the best Panama - San Diego flight prices

What cabin class options are available on Panama to San Diego flights?

There are 2 cabin classes available to choose from on Panama to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama to San Diego flights?

No. A direct flight is the cheapest option for a flight between Panama to San Diego.

Cheap Panama to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to San Diego

Best Price Found

$244

Fastest flight time

6h 52m

Direct flights

Mon, Tue, Wed, Thu and Sat

Airports in San Diego

1 airport
The best one-way flight to San Diego from Panama in the past 72 hours is $244. The best round-trip flight deal from Panama to San Diego found on momondo in the last 72 hours is $234.
The fastest flight from Panama to San Diego takes 6h 52m
Direct flights go from Panama to San Diego on Monday, Tuesday, Wednesday, Thursday and Saturday. The only airline offering direct flights is Copa Airlines.
There is 1 airport in San Diego. From Panama there are direct flights to San Diego (SAN).
Search flight deals

  • When did momondo last update prices for flights from Panama to San Diego Airport?

    Prices for flights from Panama to San Diego Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Panama to San Diego Airport?

  • How old do you have to be to fly from Panama to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama to San Diego?

Best airlines flying from Panama to San Diego

Compare and see reviews for airlines that fly from Panama to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $224Free CancellationRating
7.6
1,557 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $361Free CancellationRating
7.4
9,106 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Borrego Springs
Imperial Beach
La Mesa
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama to San Diego with flexible booking policies on momondo?

Flights from Panama to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama to San Diego?

Once all potential Panama to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to San Diego right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Diego from Panama. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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