Cheap flights from Panama City to Los Angeles from $381

The month of October is, on average, the cheapest month to fly to Los Angeles from Panama City, with most prices found around $618. If you aren’t able to travel during the month of October, then book flights to Los Angeles from Panama City during December instead. Flights to Los Angeles in December, while not as cheap as those in October, still average around $622.

Our data shows that Tuesday is the least expensive day to fly to Los Angeles. Tickets to fly out on this day can be as low as $749. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Los Angeles on Saturday is $1,061.

Our most recent data shows that the best time of day to fly to Los Angeles is in the afternoon. Flights from Panama City to Los Angeles during this time can be as low as $679. In the morning is when there is more demand to fly to Los Angeles, so prices are often more expensive at around $907 per ticket.

Fly from Panama City Tocumen Intl to Los Angeles Los Angeles for the best Panama City Tocumen Intl - Los Angeles Los Angeles flight prices

You are more likely to see cheaper flights to Los Angeles from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Los Angeles for around $671 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Los Angeles from Panama City for as low as $572 on momondo.

There are 3 cabin classes available to choose from on Panama City to Los Angeles flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 10% on your flight if you consider stops on a Panama City to Los Angeles flight.

As of August 2026, prices for Panama City to Los Angeles flights are approximately 19% more expensive when compared to flights at the same time last year.

Historically, on average around 8% of flights between Panama City and Los Angeles have experienced a delay on any given week. The average delay length over the past 12 months has been 146 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

San Salvador (SAL) was the most common stop: 62% of momondo users choosing 1-stop flights on this route connected there.

Flights via San Salvador (SAL) offer the lowest average round-trip price of $786.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 8h 56m.

Houston (IAH) has the shortest average layover time for this route: 1h 20m.

10 flights are operational daily from Panama City to Los Angeles as of August 2026. The most popular departure time for this route is 7:00AM, with 41% of flights per day taking off at noon.

71 flights are operational weekly from Panama City to Los Angeles as of August 2026. The most popular departure day for this route is Tue, with 15% of flights per week taking off on this day.