Cheap flights from Panama City to Los Angeles from $331

The month of December is, on average, the cheapest month to fly to Los Angeles from Panama City, with most prices found around $622. If you aren’t able to travel during the month of December, then book flights to Los Angeles from Panama City during February instead. Flights to Los Angeles in February, while not as cheap as those in December, still average around $622.

Our data shows that Thursday is the least expensive day to fly to Los Angeles. Tickets to fly out on this day can be as low as $806. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Los Angeles on Friday is $1,721.

Our most recent data shows that the best time of day to fly to Los Angeles is in the afternoon. Flights from Panama City to Los Angeles during this time can be as low as $749. In the morning is when there is more demand to fly to Los Angeles, so prices are often more expensive at around $995 per ticket.

Fly from Panama City Tocumen Intl to Los Angeles for the best Panama City Tocumen Intl - Los Angeles flight prices

You are more likely to see cheaper flights to Los Angeles from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Los Angeles for around $678 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Los Angeles from Panama City for as low as $565 on momondo.

There are 3 cabin classes available to choose from on Panama City to Los Angeles flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 8% on your flight if you consider stops on a Panama City to Los Angeles flight.

As of September 2026, prices for Panama City to Los Angeles flights are approximately 70% more expensive when compared to flights at the same time last year.

Copa Airlines and Delta are the most popular carriers operating from Panama City Tocumen Intl to Los Angeles

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Los Angeles from Panama City according to our data. Copa Airlines is the first choice among our users, with 72% of people opting to fly with this airline when traveling to Los Angeles. Keep in mind that there are 3 different airlines that fly to Los Angeles on a routine basis, so you have a few additional options to choose from.

Historically, on average around 8% of flights between Panama City and Los Angeles have experienced a delay on any given week. The average delay length over the past 12 months has been 149 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

Houston (IAH) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via San Salvador (SAL) offer the lowest average round-trip price of $569.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 8h 59m.

Houston (IAH) has the shortest average layover time for this route: 1h 20m.

8 flights are operational daily from Panama City to Los Angeles as of September 2026. The most popular departure time for this route is 7:00AM, with 41% of flights per day taking off at noon.

59 flights are operational weekly from Panama City to Los Angeles as of September 2026. The most popular departure day for this route is Mon, with 15% of flights per week taking off on this day.