Cheap flights from Panama City to Boston from $325

In general, November is the cheapest month to fly from Panama City to Boston. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $615. If you aren’t able to travel during the month of November, then book flights to Boston from Panama City during March instead. Flights to Boston in March, while not as cheap as those in November, still average around $620.

The cheapest day to depart from Panama City to Boston is on a Thursday when prices can be found for as low as $581. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Boston on Monday is $852.

According to our data, the cheapest time of day to fly to Boston is in the afternoon. momondo users have found flights departing from Panama City to Boston in the afternoon for as low as $632. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Boston, so prices are often more expensive at around $670 per ticket.

Fly from Panama City Tocumen Intl to Boston Logan Intl for the best Panama City Tocumen Intl - Boston Logan Intl flight prices

You are more likely to see cheaper flights to Boston from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Boston for around $680 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Boston from Panama City for as low as $453 on momondo.

There are 2 cabin classes available to choose from on Panama City to Boston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 12% on your flight if you consider stops on a Panama City to Boston flight.

As of June 2026, prices for Panama City to Boston flights are approximately 8% more expensive when compared to flights at the same time last year.

Avianca is the most popular carrier operating from Panama City Tocumen Intl to Boston Logan Intl

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Boston from Panama City according to our data. Copa Airlines is the first choice among our users, with 76% of people opting to fly with this airline when traveling to Boston. Keep in mind that there are 3 different airlines that fly to Boston on a routine basis, so you have a few additional options to choose from.

Newark (EWR) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Newark (EWR) offer the lowest average round-trip price of $646.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 8h 20m.

San Salvador (SAL) has the shortest average layover time for this route: 1h 58m.

As of June 2026, there are 1 flights per day flying from Panama City to Boston. The most common time of day flights depart is 4:00PM, with 100% of flights taking off in the afternoon.

As of June 2026, 11 flights take off from Panama City and land in Boston each week. The most common flight departure day for this route is Mon, with 27% of weekly flights taking off on this day.