Cheap flights from Panama City to Boston from $278

In general, August is the cheapest month to fly from Panama City to Boston. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $517. If you aren’t able to travel during the month of August, then book flights to Boston from Panama City during May instead. Flights to Boston in May, while not as cheap as those in August, still average around $566.

The cheapest day to depart from Panama City to Boston is on a Monday when prices can be found for as low as $575. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Boston on Tuesday is $642.

According to our data, the cheapest time of day to fly to Boston is in the morning. momondo users have found flights departing from Panama City to Boston in the morning for as low as $581. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Boston, so prices are often more expensive at around $594 per ticket.

Fly from Panama City Tocumen Intl to Boston Logan Intl for the best Panama City Tocumen Intl - Boston Logan Intl flight prices

You are more likely to see cheaper flights to Boston from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Boston for around $636 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Boston from Panama City for as low as $427 on momondo.

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Boston Logan Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 50% on your flight if you consider stops on a Panama City to Boston flight.

As of March 2026, prices for Panama City to Boston flights are approximately 34% more expensive when compared to flights at the same time last year.

Newark (EWR) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Newark (EWR) offer the lowest average round-trip price of $646.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 8h 20m.

San Salvador (SAL) has the shortest average layover time for this route: 1h 58m.

As of March 2026, there are 2 flights per day flying from Panama City to Boston. The most common time of day flights depart is 4:00PM, with 100% of flights taking off in the afternoon.

As of March 2026, 14 flights take off from Panama City and land in Boston each week. The most common flight departure day for this route is Mon, with 14% of weekly flights taking off on this day.