Cheap flights from Panama City to Houston from $338

The month of June is, on average, the cheapest month to fly to Houston George Bush Intcntl Airport from Panama City, with most prices found around $681. If you are unable to visit Houston George Bush Intcntl Airport during the month of June, then departing from Panama City during the month March is also very affordable. Most momondo users find prices during this month for around $818.

The cheapest day to depart from Panama City to Houston George Bush Intcntl Airport is on a Thursday. Travelers who choose to depart for Houston George Bush Intcntl Airport on a Thursday will often find tickets for as low as $758. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Houston George Bush Intcntl Airport on Sunday is $867.

Our data shows that the cheapest Panama City to Houston George Bush Intcntl Airport flights are usually those with departure times in the afternoon. Our users have found flights to Houston George Bush Intcntl Airport in the afternoon for as low as $775. Try not to purchase tickets in the morning because they tend to be around $782. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Panama City Tocumen Intl to Houston George Bush Intcntl for the best Panama City Tocumen Intl - Houston George Bush Intcntl flight prices

There are 3 cabin classes available to choose from on Panama City to Houston George Bush Intcntl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 46% on your flight if you consider stops on a Panama City to Houston George Bush Intcntl Airport flight.

Historically, on average around 5% of flights between Panama City and Houston have experienced a delay on any given week. The average delay length over the past 12 months has been 130 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.

2 flights are operational daily from Panama City to Houston George Bush Intcntl Airport as of October 2026. The most popular departure time for this route is 10:00AM, with 50% of flights per day taking off at noon.

16 flights are operational weekly from Panama City to Houston George Bush Intcntl Airport as of October 2026. The most popular departure day for this route is Sun, with 25% of flights per week taking off on this day.