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Cheap flights from Panama City to Los Angeles from $381

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Los Angeles departing on 11/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:35 pm - 9:14 amPTY-SNA
20h 39m1 stop
United Airlines Logo
4:10 pm - 2:45 pmSNA-PTY
19h 35m2 stops
$653United Airlines
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Tue, Dec 2 - Tue, Dec 16
United Airlines Logo
4:41 pm - 9:58 amPTY-SNA
20h 17m2 stops
United Airlines Logo
6:25 pm - 5:07 pmSNA-PTY
19h 42m2 stops
$674United Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
4:41 pm - 11:17 amPTY-SNA
21h 36m1 stop
United Airlines Logo
7:50 pm - 5:07 pmSNA-PTY
18h 17m2 stops
$695United Airlines
Find Deal
Thu, Nov 27 - Sat, Dec 6
United Airlines Logo
8:55 am - 9:23 amPTY-SNA
27h 28m2 stops
United Airlines Logo
6:25 pm - 5:07 pmSNA-PTY
19h 42m2 stops
$912United Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
United Airlines Logo
3:35 pm - 8:54 amPTY-SNA
20h 19m1 stop
United Airlines Logo
7:50 pm - 6:49 pmSNA-PTY
19h 59m1 stop
$970United Airlines
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Fri, Nov 28 - Fri, Dec 5
United Airlines Logo
4:41 pm - 2:04 pmPTY-SNA
24h 23m1 stop
United Airlines Logo
12:15 pm - 2:45 pmSNA-PTY
23h 30m1 stop
$7,172United Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 16

United Airlines flights from Panama City to Santa Ana, California

Our best United Airlines deals on Panama City to Santa Ana, California flight tickets
United Airlines
Dec 2
PTY3:35 pmPanama City Tocumen Intl
20h 39m
1 stop
SNA9:14 amSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA4:10 pmSanta Ana J. Wayne/Orange Cnty
19h 35m
2 stops
PTY2:45 pmPanama City Tocumen Intl
$653
Find similar
United Airlines
Nov 26
PTY4:41 pmPanama City Tocumen Intl
20h 17m
2 stops
SNA9:58 amSanta Ana J. Wayne/Orange Cnty
Dec 3
SNA6:25 pmSanta Ana J. Wayne/Orange Cnty
19h 42m
2 stops
PTY5:07 pmPanama City Tocumen Intl
$674
Find similar
United Airlines
Nov 27
PTY4:41 pmPanama City Tocumen Intl
21h 36m
1 stop
SNA11:17 amSanta Ana J. Wayne/Orange Cnty
Dec 6
SNA7:50 pmSanta Ana J. Wayne/Orange Cnty
18h 17m
2 stops
PTY5:07 pmPanama City Tocumen Intl
$695
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Panama City to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 12/2

3:35 pm-9:14 am

1 stop20h 39m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

4:10 pm-2:45 pm

2 stops19h 35m

$653

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 11/26

4:41 pm-9:58 am

2 stops20h 17m

Santa Ana J. Wayne/Orange Cnty

Wed 12/3

6:25 pm-5:07 pm

2 stops19h 42m

$674

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Thu 11/27

4:41 pm-11:17 am

1 stop21h 36m

Santa Ana J. Wayne/Orange Cnty

Sat 12/6

7:50 pm-5:07 pm

2 stops18h 17m

$695

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 11/28

8:55 am-9:23 am

2 stops27h 28m

Santa Ana J. Wayne/Orange Cnty

Fri 12/5

6:25 pm-5:07 pm

2 stops19h 42m

$912

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 11/28

3:35 pm-8:54 am

1 stop20h 19m

Santa Ana J. Wayne/Orange Cnty

Fri 12/5

7:50 pm-6:49 pm

1 stop19h 59m

$970

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 12/2

4:41 pm-2:04 pm

1 stop24h 23m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

12:15 pm-2:45 pm

1 stop23h 30m

$7,172

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 11/26

4:41 pm-12:28 pm

2 stops22h 47m

$381

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 12/1

2:43 pm-9:53 am

2 stops22h 10m

$404

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 11/14

3:35 pm-8:54 am

1 stop20h 19m

$407

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 11/14

8:55 am-10:19 pm

2 stops16h 24m

$411

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Panama City to Santa Ana, California is on a Tuesday. Travelers who choose to depart for Santa Ana, California on a Tuesday will often find tickets for as low as $646. The most expensive day to fly to Santa Ana, California is Monday, with ticket prices averaging around $754.

When to book flights from Panama City to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Santa Ana, California (PTY to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santa Ana, California

Direct flights

None
There are no direct flights from Panama City to Santa Ana, California. There are no popular flight routes from Panama City to Santa Ana, California.
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  • How far is Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2971.5 mi away from Panama City Tocumen Intl. A reasonable flight in good conditions will take 20h 17m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santa Ana?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Ana from Panama City.

Can I find flights from Panama City to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Santa Ana?

momondo provides multiple filters to help you find the best flight to Santa Ana from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from Panama City and alert you when they change.

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