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Cheap flights from Panama City to Los Angeles from $397

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Los Angeles departing on 3/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:55 am - 9:36 pm
PTY
-
SNA
15h 41m
1 stop
United Airlines Logo
4:12 pm - 2:14 pm
SNA
-
PTY
20h 02m
2 stops
$686United Airlines
Mon, Jul 27 - Tue, Aug 4
United Airlines Logo
3:41 pm - 1:15 pm
PTY
-
SNA
23h 34m
2 stops
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
$696United Airlines
Wed, Mar 25 - Wed, Apr 1
United Airlines Logo
7:55 am - 9:36 pm
PTY
-
SNA
15h 41m
1 stop
United Airlines Logo
7:55 pm - 4:12 pm
SNA
-
PTY
18h 17m
2 stops
$707United Airlines
Fri, Jul 24 - Mon, Aug 3
American Airlines Logo
3:10 pm - 10:05 am
PTY
-
SNA
20h 55m
2 stops
American Airlines Logo
7:18 pm - 3:01 pm
SNA
-
PTY
17h 43m
2 stops
$710American Airlines
Thu, Mar 26 - Thu, Apr 2
United Airlines Logo
3:41 pm - 11:27 am
PTY
-
SNA
21h 46m
1 stop
United Airlines Logo
3:29 pm - 2:14 pm
SNA
-
PTY
20h 45m
1 stop
$729United Airlines
Wed, Mar 25 - Fri, Apr 3
United Airlines Logo
3:41 pm - 1:15 pm
PTY
-
SNA
23h 34m
2 stops
United Airlines Logo
6:28 pm - 6:37 pm
SNA
-
PTY
22h 09m
2 stops
$739United Airlines
Wed, Mar 25 - Wed, Apr 1
United Airlines Logo
7:55 am - 9:36 pm
PTY
-
SNA
15h 41m
1 stop
United Airlines Logo
2:58 pm - 4:12 pm
SNA
-
PTY
23h 14m
1 stop
$750United Airlines
Sun, Jul 26 - Sun, Aug 2
United Airlines Logo
3:41 pm - 9:48 am
PTY
-
SNA
20h 07m
2 stops
United Airlines Logo
6:28 pm - 4:12 pm
SNA
-
PTY
19h 44m
2 stops
$767United Airlines
Fri, Mar 27 - Mon, Apr 6
United Airlines Logo
7:55 am - 8:34 pm
PTY
-
SNA
14h 39m
2 stops
United Airlines Logo
2:54 pm - 2:14 pm
SNA
-
PTY
21h 20m
2 stops
$771United Airlines
Tue, Jul 28 - Sun, Aug 2
United Airlines Logo
3:41 pm - 12:22 pm
PTY
-
SNA
22h 41m
2 stops
United Airlines Logo
1:21 pm - 2:14 pm
SNA
-
PTY
22h 53m
2 stops
$778United Airlines
Thu, Mar 26 - Thu, Apr 2

United Airlines flights from Panama City to Santa Ana

Our best United Airlines deals on Panama City to Santa Ana flight tickets
United Airlines
Jul 27
PTY7:55 amPanama City Tocumen Intl
15h 41m
1 stop
SNA9:36 pmSanta Ana J. Wayne/Orange Cnty
Aug 4
SNA4:12 pmSanta Ana J. Wayne/Orange Cnty
20h 02m
2 stops
PTY2:14 pmPanama City Tocumen Intl
$686
United Airlines
Mar 25
PTY3:41 pmPanama City Tocumen Intl
23h 34m
2 stops
SNA1:15 pmSanta Ana J. Wayne/Orange Cnty
Apr 1
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$696
United Airlines
Jul 24
PTY7:55 amPanama City Tocumen Intl
15h 41m
1 stop
SNA9:36 pmSanta Ana J. Wayne/Orange Cnty
Aug 3
SNA7:55 pmSanta Ana J. Wayne/Orange Cnty
18h 17m
2 stops
PTY4:12 pmPanama City Tocumen Intl
$707

American Airlines flights from Panama City to Santa Ana

Our best American Airlines deals on Panama City to Santa Ana flight tickets
American Airlines
Mar 26
PTY3:10 pmPanama City Tocumen Intl
20h 55m
2 stops
SNA10:05 amSanta Ana J. Wayne/Orange Cnty
Apr 2
SNA7:18 pmSanta Ana J. Wayne/Orange Cnty
17h 43m
2 stops
PTY3:01 pmPanama City Tocumen Intl
$710
American Airlines
Mar 28
PTY3:10 pmPanama City Tocumen Intl
19h 45m
2 stops
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
Apr 5
SNA4:32 pmSanta Ana J. Wayne/Orange Cnty
18h 09m
2 stops
PTY12:41 pmPanama City Tocumen Intl
$945
American Airlines
Mar 28
PTY3:10 pmPanama City Tocumen Intl
19h 45m
2 stops
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
Apr 7
SNA1:30 pmSanta Ana J. Wayne/Orange Cnty
21h 16m
2 stops
PTY12:46 pmPanama City Tocumen Intl
$948

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 7/27

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Tue 8/4

4:12 pm-2:14 pm

2 stops20h 02m

$686

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 3/25

3:41 pm-1:15 pm

2 stops23h 34m

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

8:00 am-6:37 pm

1 stop8h 37m

$696

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 7/24

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Mon 8/3

7:55 pm-4:12 pm

2 stops18h 17m

$707

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Thu 3/26

3:10 pm-10:05 am

2 stops20h 55m

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

7:18 pm-3:01 pm

2 stops17h 43m

$710

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 3/25

3:41 pm-11:27 am

1 stop21h 46m

Santa Ana J. Wayne/Orange Cnty

Fri 4/3

3:29 pm-2:14 pm

1 stop20h 45m

$729

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 3/25

3:41 pm-1:15 pm

2 stops23h 34m

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

6:28 pm-6:37 pm

2 stops22h 09m

$739

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 7/26

7:55 am-9:36 pm

1 stop15h 41m

Santa Ana J. Wayne/Orange Cnty

Sun 8/2

2:58 pm-4:12 pm

1 stop23h 14m

$750

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 3/27

3:41 pm-9:48 am

2 stops20h 07m

Santa Ana J. Wayne/Orange Cnty

Mon 4/6

6:28 pm-4:12 pm

2 stops19h 44m

$767

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 7/28

7:55 am-8:34 pm

2 stops14h 39m

Santa Ana J. Wayne/Orange Cnty

Sun 8/2

2:54 pm-2:14 pm

2 stops21h 20m

$771

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Thu 3/26

3:41 pm-12:22 pm

2 stops22h 41m

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

1:21 pm-2:14 pm

2 stops22h 53m

$778

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Panama City to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty?

United Airlines is the most popular carrier operating from Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty

What airlines fly to Santa Ana?

Copa Airlines, Avianca and American Airlines are the top three most popular airlines that fly to Santa Ana from Panama City according to our data. Copa Airlines is the first choice among our users, with 70% of people opting to fly with this airline when traveling to Santa Ana. Keep in mind that there are 4 different airlines that fly to Santa Ana on a routine basis, so you have a few additional options to choose from.

When to book flights from Panama City to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Santa Ana (PTY to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santa Ana

Fastest flight time

13h 07m

Direct flights

None
The fastest flight from Panama City to Santa Ana takes 13h 07m
There are no direct flights from Panama City to Santa Ana. There are no popular flight routes from Panama City to Santa Ana.
Search flight deals

  • How far is Panama City Tocumen Intl to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2971.5 mi away from Panama City Tocumen Intl. A reasonable flight in good conditions will take 13h 07m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santa Ana?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Ana from Panama City.

Can I find flights from Panama City to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Santa Ana?

momondo provides multiple filters to help you find the best flight to Santa Ana from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Santa Ana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Ana, momondo offers a useful price alert feature which will track prices for flights to Santa Ana from Panama City and alert you when they change.

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