What is the cheapest airline that flies from Panama City Tocumen Intl to Lambert-St Louis?

American Airlines is the most popular carrier operating from Panama City Tocumen Intl to Lambert-St Louis

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?

Prices for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport were last updated today.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?

There is 1 operator available for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport as of December 2025.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Lambert-St Louis Airport.

What documentation or ID do you need to fly to Lambert-St Louis Airport?

The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$252 Cheap Flights from Panama City to St. Louis in 2025/26

Q: What is the typical price of a round-trip flight between Panama City and St. Louis?

Prices are currently typical for flights on this route. Typical prices usually range from $429 to $694. The lowest price recently found on this route was $537.

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4:41 pm - 9:22 am

PTY

STL

17h 41m1 stop

4:35 pm - 5:07 pm

STL

PTY

23h 32m1 stop

$537United Airlines

Sat, Feb 7 - Tue, Feb 10

2:27 pm - 11:03 am

PTY

STL

21h 36m2 stops

5:04 pm - 1:27 pm

STL

PTY

19h 23m2 stops

$551American Airlines

Sat, Feb 7 - Tue, Feb 10

4:50 pm - 10:20 am

PTY

STL

18h 30m2 stops

6:43 pm - 1:50 pm

STL

PTY

18h 07m2 stops

$556American Airlines

Sun, Feb 8 - Tue, Feb 24

4:41 pm - 11:02 am

PTY

STL

19h 21m2 stops

6:30 am - 7:38 pm

STL

PTY

12h 08m2 stops

$593United Airlines

Fri, Jan 23 - Tue, Jan 27

8:55 am - 9:55 pm

PTY

STL

14h 00m1 stop

4:42 pm - 2:45 pm

STL

PTY

21h 03m1 stop

$650United Airlines

Mon, Dec 29 - Sat, Jan 10

8:55 am - 10:00 pm

PTY

STL

14h 05m1 stop

10:07 am - 7:38 pm

STL

PTY

8h 31m1 stop

$918United Airlines

Fri, Jan 23 - Tue, Jan 27

11:25 am - 10:13 am

PTY

STL

23h 48m3 stops

4:05 pm - 12:40 am

STL

PTY

31h 35m3 stops

$1,443Multiple Airlines

Sat, Feb 7 - Tue, Feb 10

11:25 am - 10:13 am

PTY

STL

23h 48m3 stops

4:05 pm - 2:00 pm

STL

PTY

20h 55m2 stops

$1,659Multiple Airlines

Sat, Feb 7 - Tue, Feb 10

7:50 pm - 3:29 pm

PTY

STL

44h 39m2 stops

6:30 am - 2:55 pm

STL

PTY

31h 25m3 stops

$7,716Multiple Airlines

Sun, Feb 8 - Tue, Feb 24

American Airlines flights from Panama City to St. Louis

Our best American Airlines deals on Panama City to St. Louis flight tickets

American Airlines

Feb 7

PTY2:27 pmPanama City Tocumen Intl

21h 36m

2 stops

STL11:03 amLambert-St Louis

Feb 10

STL5:04 pmLambert-St Louis

19h 23m

2 stops

PTY1:27 pmPanama City Tocumen Intl

$551

Find similar

American Airlines

Feb 8

PTY4:50 pmPanama City Tocumen Intl

18h 30m

2 stops

STL10:20 amLambert-St Louis

Feb 24

STL6:43 pmLambert-St Louis

18h 07m

2 stops

PTY1:50 pmPanama City Tocumen Intl

$556

Find similar

United Airlines flights from Panama City to St. Louis

Our best United Airlines deals on Panama City to St. Louis flight tickets

United Airlines

Feb 7

PTY4:41 pmPanama City Tocumen Intl

20h 48m

2 stops

STL12:29 pmLambert-St Louis

Feb 10

STL4:35 pmLambert-St Louis

23h 32m

1 stop

PTY5:07 pmPanama City Tocumen Intl

$537

Find similar

United Airlines

Jan 23

PTY4:41 pmPanama City Tocumen Intl

22h 47m

2 stops

STL2:28 pmLambert-St Louis

Jan 27

STL6:30 amLambert-St Louis

12h 08m

2 stops

PTY7:38 pmPanama City Tocumen Intl

$593

Find similar

United Airlines

Dec 29

PTY8:55 amPanama City Tocumen Intl

14h 00m

1 stop

STL9:55 pmLambert-St Louis

Jan 10

STL4:42 pmLambert-St Louis

21h 03m

1 stop

PTY2:45 pmPanama City Tocumen Intl

$650

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 2/7

4:41 pm-9:22 am

1 stop17h 41m

Lambert-St Louis

Tue 2/10

4:35 pm-5:07 pm

1 stop23h 32m

$537

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 2/7

2:27 pm-11:03 am

2 stops21h 36m

Lambert-St Louis

Tue 2/10

5:04 pm-1:27 pm

2 stops19h 23m

$551

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 2/8

4:50 pm-10:20 am

2 stops18h 30m

Lambert-St Louis

Tue 2/24

6:43 pm-1:50 pm

2 stops18h 07m

$556

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Fri 1/23

4:41 pm-11:02 am

2 stops19h 21m

Lambert-St Louis

Tue 1/27

6:30 am-7:38 pm

2 stops12h 08m

$593

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 12/29

8:55 am-9:55 pm

1 stop14h 00m

Lambert-St Louis

Sat 1/10

4:42 pm-2:45 pm

1 stop21h 03m

$650

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Fri 1/23

8:55 am-10:00 pm

1 stop14h 05m

Lambert-St Louis

Tue 1/27

10:07 am-7:38 pm

1 stop8h 31m

$918

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 2/7

11:25 am-10:13 am

3 stops23h 48m

Lambert-St Louis

Tue 2/10

4:05 pm-12:40 am

3 stops31h 35m

$1,443

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sat 2/7

11:25 am-10:13 am

3 stops23h 48m

Lambert-St Louis

Tue 2/10

4:05 pm-2:00 pm

2 stops20h 55m

$1,659

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 2/8

7:50 pm-3:29 pm

2 stops44h 39m

Lambert-St Louis

Tue 2/24

6:30 am-2:55 pm

3 stops31h 25m

$7,716

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 1/22

4:50 pm-11:59 pm

1 stop8h 09m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Panama City and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, June is the cheapest month to fly from Panama City to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. The month of February is another great option to travel to St. Louis, with average flight prices from Panama City averaging around $398.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $496. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $611. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Panama City at noon is the least expensive time of day to depart. momondo users have found prices as low as $535 when looking at flights departing at noon. In the morning is when there is more demand to fly to St. Louis, so prices are often more expensive at around $574 per ticket.

When to book flights from Panama City to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to St. Louis according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to St. Louis (PTY to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to St. Louis

Fastest flight time	11h 20m
Direct flights	None

The fastest flight from Panama City to St. Louis takes 11h 20m

There are no direct flights from Panama City to St. Louis. There are no popular flight routes from Panama City to St. Louis.

Search flight deals

How far is Panama City Tocumen Intl to Lambert-St Louis by plane?
The straight-line distance from Panama City Tocumen Intl to Lambert-St Louis is 2151.1 mi. Typically, this will take 11h 20m by plane in normal conditions.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?
Prices for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport were last updated today.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?
There is 1 operator available for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport as of December 2025.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Panama City to St. Louis?
momondo data reveals that the most frequently booked airline on the route from Panama City to St. Louis is United Airlines, representing 100% of all bookings.

Best airlines flying from Panama City to St. Louis

Compare and see reviews for airlines that fly from Panama City to St. Louis with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $478	Free Cancellation	Rating 7.4 9,091 reviews		Search United Airlines flights

St. Charles

Chesterfield

Hermann

Fairview Heights

Maryland Heights

O'Fallon

Florissant

Fenton

Wentzville

St. Peters

Collinsville

Alton

Clayton

Festus

Glencoe

Farmington

Eureka

Edwardsville

Litchfield

Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to St. Louis?

Finding the right flight to St. Louis from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to St. Louis quick and easy, saving you time and money.

Can I find flights from Panama City to St. Louis with flexible booking policies on momondo?

Flights from Panama City to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Panama City.

I’m not ready to book a flight from Panama City to St. Louis right now. Can momondo alert me if prices change?

If you are simply researching potential flights to St. Louis, momondo offers a useful price alert feature which will track prices for flights to St. Louis from Panama City and alert you when they change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Panama City to St. Louis from $317

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

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Find the cheapest flights from Panama City to St. Louis

Cheap round-trip flights

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American Airlines flights from Panama City to St. Louis

Our best American Airlines deals on Panama City to St. Louis flight tickets

United Airlines flights from Panama City to St. Louis

Our best United Airlines deals on Panama City to St. Louis flight tickets

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See travel insights to St. Louis from

How to get the cheapest flight ticket from Panama City to St. Louis

What is the typical price of a round-trip flight between Panama City and St. Louis?

What is the cheapest month to fly to St. Louis?

What is the cheapest day to depart on your flight to St. Louis?

What is the cheapest time of day to depart on your flight to St. Louis?

What is the cheapest airline that flies from Panama City Tocumen Intl to Lambert-St Louis?

American Airlines is the most popular carrier operating from Panama City Tocumen Intl to Lambert-St Louis

When to book flights from Panama City to St. Louis

Cheap Panama City to St. Louis (PTY to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to St. Louis

Fastest flight time

Direct flights

How far is Panama City Tocumen Intl to Lambert-St Louis by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Lambert-St Louis Airport?

What documentation or ID do you need to fly to Lambert-St Louis Airport?

What is the most popular airline from Panama City to St. Louis?

Best airlines flying from Panama City to St. Louis

Compare and see reviews for airlines that fly from Panama City to St. Louis with momondo

Traveling to a place near St. Louis?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to St. Louis?

Can I find flights from Panama City to St. Louis with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to St. Louis?

I’m not ready to book a flight from Panama City to St. Louis right now. Can momondo alert me if prices change?

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Missouri