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Cheap flights from Panama City to San Diego from $324

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to San Diego departing on 9/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:55 am - 7:57 pm
PTY
-
SAN
14h 02m
1 stop
United Airlines Logo
5:00 pm - 7:38 pm
SAN
-
PTY
23h 38m
2 stops
$620United Airlines
vie., nov. 6 - dom., nov. 8
United Airlines Logo
8:55 am - 7:57 pm
PTY
-
SAN
14h 02m
1 stop
United Airlines Logo
5:00 pm - 7:38 pm
SAN
-
PTY
23h 38m
2 stops
$631United Airlines
vie., nov. 6 - dom., nov. 8
American Airlines Logo
1:39 pm - 8:58 am
PTY
-
SAN
21h 19m
2 stops
American Airlines Logo
12:32 pm - 12:39 pm
SAN
-
PTY
22h 07m
1 stop
$711American Airlines
vie., ago. 14 - mar., ago. 18
United Airlines Logo
3:30 pm - 8:22 am
PTY
-
SAN
18h 52m
2 stops
United Airlines Logo
5:30 pm - 6:37 pm
SAN
-
PTY
23h 07m
1 stop
$720United Airlines
mié., jul. 22 - dom., jul. 26
United Airlines Logo
8:55 am - 10:42 pm
PTY
-
SAN
16h 47m
2 stops
United Airlines Logo
5:00 pm - 7:38 pm
SAN
-
PTY
23h 38m
2 stops
$722United Airlines
vie., nov. 6 - dom., nov. 8
Copa Airlines Logo
1:45 pm - 5:26 pm
PTY
-
SAN
6h 41mnonstop
Copa Airlines Logo
10:00 pm - 7:10 am
SAN
-
PTY
6h 10mnonstop
$736Copa Airlines
mié., dic. 2 - dom., dic. 6
United Airlines Logo
3:30 pm - 10:08 am
PTY
-
SAN
20h 38m
2 stops
United Airlines Logo
6:55 pm - 6:37 pm
SAN
-
PTY
21h 42m
2 stops
$741United Airlines
lun., jul. 27 - vie., jul. 31
Copa Airlines Logo
7:55 am - 9:24 pm
PTY
-
SAN
15h 29m
1 stop
Copa Airlines Logo
6:15 am - 6:37 pm
SAN
-
PTY
10h 22m
1 stop
$753Copa Airlines
mié., jul. 22 - dom., jul. 26
United Airlines Logo
3:30 pm - 9:05 am
PTY
-
SAN
19h 35m
2 stops
United Airlines Logo
8:32 pm - 6:37 pm
SAN
-
PTY
20h 05m
2 stops
$762United Airlines
mié., jul. 22 - dom., jul. 26
United Airlines Logo
7:55 am - 9:24 pm
PTY
-
SAN
15h 29m
1 stop
United Airlines Logo
7:41 pm - 4:12 pm
SAN
-
PTY
18h 31m
2 stops
$767United Airlines
mié., jul. 22 - dom., jul. 26

American Airlines flights from Panama City to San Diego

Our best American Airlines deals on Panama City to San Diego flight tickets
American Airlines
Aug 14
PTY1:39 pmPanama City Tocumen Intl
21h 19m
2 stops
SAN8:58 amSan Diego
Aug 18
SAN12:32 pmSan Diego
22h 07m
1 stop
PTY12:39 pmPanama City Tocumen Intl
$711
American Airlines
Dec 2
PTY4:37 pmPanama City Tocumen Intl
20h 17m
2 stops
SAN9:54 amSan Diego
Dec 6
SAN7:30 pmSan Diego
17h 07m
2 stops
PTY3:37 pmPanama City Tocumen Intl
$768
American Airlines
Jul 10
PTY1:14 pmPanama City Tocumen Intl
21h 54m
2 stops
SAN9:08 amSan Diego
Jul 16
SAN10:25 pmSan Diego
11h 49m
1 stop
PTY12:14 pmPanama City Tocumen Intl
$799

Copa Airlines flights from Panama City to San Diego

Our best Copa Airlines deals on Panama City to San Diego flight tickets
Copa Airlines
Dec 2
PTY1:45 pmPanama City Tocumen Intl
6h 41m
SAN5:26 pmSan Diego
Dec 6
SAN10:00 pmSan Diego
6h 10m
PTY7:10 amPanama City Tocumen Intl
$736
Copa Airlines
Jul 22
PTY7:55 amPanama City Tocumen Intl
15h 29m
1 stop
SAN9:24 pmSan Diego
Jul 26
SAN6:15 amSan Diego
10h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$753
Copa Airlines
Jul 2
PTY10:00 amPanama City Tocumen Intl
11h 50m
1 stop
SAN7:50 pmSan Diego
Jul 16
SAN5:15 pmSan Diego
18h 59m
1 stop
PTY2:14 pmPanama City Tocumen Intl
$784

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated junio 6, 2026.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 11/6

8:55 am-7:57 pm

1 stop14h 02m

San Diego

dom. 11/8

5:00 pm-7:38 pm

2 stops23h 38m

$620

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 11/6

8:55 am-7:57 pm

1 stop14h 02m

San Diego

dom. 11/8

5:00 pm-7:38 pm

2 stops23h 38m

$631

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 8/14

1:39 pm-8:58 am

2 stops21h 19m

San Diego

mar. 8/18

12:32 pm-12:39 pm

1 stop22h 07m

$711

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 7/22

3:30 pm-8:22 am

2 stops18h 52m

San Diego

dom. 7/26

5:30 pm-6:37 pm

1 stop23h 07m

$720

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 11/6

8:55 am-10:42 pm

2 stops16h 47m

San Diego

dom. 11/8

5:00 pm-7:38 pm

2 stops23h 38m

$722
Quickest round-trip

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 12/2

1:45 pm-5:26 pm

Nonstop6h 41m

San Diego

dom. 12/6

10:00 pm-7:10 am

Nonstop6h 10m

$736

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

lun. 7/27

3:30 pm-10:08 am

2 stops20h 38m

San Diego

vie. 7/31

6:55 pm-6:37 pm

2 stops21h 42m

$741

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 7/22

7:55 am-9:24 pm

1 stop15h 29m

San Diego

dom. 7/26

6:15 am-6:37 pm

1 stop10h 22m

$753

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 7/22

3:30 pm-9:05 am

2 stops19h 35m

San Diego

dom. 7/26

8:32 pm-6:37 pm

2 stops20h 05m

$762

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 7/22

7:55 am-9:24 pm

1 stop15h 29m

San Diego

dom. 7/26

7:41 pm-4:12 pm

2 stops18h 31m

$767

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Panama City during the month November is also very affordable. Most momondo users find prices during this month for around $428.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Panama City to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $334. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $631. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest Panama City Tocumen Intl to San Diego flight route?

Fly from Panama City Tocumen Intl to San Diego for the best Panama City Tocumen Intl - San Diego flight prices

What cabin class options are available on Panama City to San Diego flights?

There are 2 cabin classes available to choose from on Panama City to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to San Diego flights?

You could potentially save up to 33% on your flight if you consider stops on a Panama City to San Diego flight.

How have Panama City to San Diego flight prices changed over time?

As of June 2026, prices for Panama City to San Diego flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to San Diego (PTY to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to San Diego

Fastest flight time

6h 29m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in San Diego

1 airport
The fastest flight from Panama City to San Diego takes 6h 29m
Direct flights go from Panama City to San Diego on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There is 1 airport in San Diego. From Panama City there are direct flights to San Diego (SAN).
Search flight deals

Frequently asked questions about flying from Panama City to San Diego

  • How far is Panama City Tocumen Intl to San Diego by plane?

    San Diego is 2903.4 mi away from Panama City Tocumen Intl. 6h 29m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to San Diego Airport?

    Prices for flights from Panama City Tocumen Intl Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to San Diego?

  • What is the most popular airline from Panama City to San Diego?

Best airlines flying from Panama City to San Diego

Compare and see reviews for airlines that fly from Panama City to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $224Free CancellationRating
7.5
1,568 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $361Free CancellationRating
7.4
9,779 reviews
Search United Airlines flights

  • Copa Airlines Flights From Panama City to San Diego

    Copa Airlines is one of the most popular airlines flying from Panama City to San Diego, operating 4 flights/week on average for this route. A good Copa Airlines flight deal for Panama City to San Diego starts from $224 round-trip, up to an average price of $631. Our users have rated Copa Airlines at 7.5/10.

  • United Airlines Flights From Panama City to San Diego

    $361 is the best United Airlines flight deal from Panama City to San Diego found on momondo over the last 72 hours. The average United Airlines ticket price found was closer to $722, however, with flight time and availability significantly affecting the price. United Airlines (7.4/10 from 9,778 user reviews) flies into San Diego from Panama City 4 times in an average week so prices can vary.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Borrego Springs
Lemon Grove
Imperial Beach
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

Finding the right flight to San Diego from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

All flight searches from Panama City to San Diego on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to San Diego?

momondo helps you find the best flight between Panama City and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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