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Cheap flights from Panama City to San Diego from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to San Diego departing on 12/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Copa Airlines Logo
1:45 pm - 5:41 pmPTY-SAN
6h 56mnonstop
Copa Airlines Logo
8:17 pm - 5:20 amSAN-PTY
6h 03mnonstop
$477Copa Airlines
Find Deal
vie., ene. 23 - dom., feb. 8
United Airlines Logo
4:41 pm - 9:20 amPTY-SAN
19h 39m2 stops
United Airlines Logo
4:10 pm - 2:45 pmSAN-PTY
19h 35m2 stops
$483United Airlines
Find Deal
vie., ene. 23 - dom., feb. 8
United Airlines Logo
4:41 pm - 10:46 amPTY-SAN
21h 05m2 stops
United Airlines Logo
4:00 pm - 2:45 pmSAN-PTY
19h 45m2 stops
$505United Airlines
Find Deal
mié., ene. 28 - jue., feb. 5
United Airlines Logo
4:41 pm - 11:14 amPTY-SAN
21h 33m1 stop
United Airlines Logo
3:40 pm - 5:07 pmSAN-PTY
22h 27m1 stop
$531United Airlines
Find Deal
vie., feb. 13 - jue., feb. 19
United Airlines Logo
11:35 am - 11:42 pmPTY-SAN
15h 07m2 stops
United Airlines Logo
7:40 am - 6:49 pmSAN-PTY
32h 09m1 stop
$532United Airlines
Find Deal
vie., dic. 12 - sáb., ene. 3
Copa Airlines Logo
1:45 pm - 5:41 pmPTY-SAN
6h 56mnonstop
Copa Airlines Logo
8:16 pm - 5:20 amSAN-PTY
6h 04mnonstop
$568Copa Airlines
Find Deal
mar., ene. 6 - vie., ene. 9
Multiple Airlines Logo
2:55 am - 8:39 amPTY-SAN
32h 44m3 stops
Multiple Airlines Logo
8:12 pm - 5:20 amSAN-PTY
6h 08mnonstop
$614Multiple Airlines
Find Deal
dom., dic. 14 - mié., dic. 24
United Airlines Logo
4:41 pm - 4:36 pmPTY-SAN
26h 55m1 stop
United Airlines Logo
6:00 pm - 5:07 pmSAN-PTY
20h 07m2 stops
$693United Airlines
Find Deal
mar., ene. 6 - vie., ene. 9
Copa Airlines Logo
11:57 am - 7:54 pmPTY-SAN
10h 57m1 stop
Copa Airlines Logo
8:17 pm - 5:20 amSAN-PTY
6h 03mnonstop
$709Copa Airlines
Find Deal
vie., ene. 23 - dom., feb. 8
United Airlines Logo
3:35 pm - 10:40 amPTY-SAN
22h 05m1 stop
United Airlines Logo
3:00 pm - 2:45 pmSAN-PTY
20h 45m1 stop
$713United Airlines
Find Deal
lun., dic. 15 - mié., dic. 24

United Airlines flights from Panama City to San Diego

Our best United Airlines deals on Panama City to San Diego flight tickets
United Airlines
Jan 23
PTY4:41 pmPanama City Tocumen Intl
28h 55m
1 stop
SAN6:36 pmSan Diego
Feb 8
SAN4:10 pmSan Diego
19h 35m
2 stops
PTY2:45 pmPanama City Tocumen Intl
$483
Find similar
United Airlines
Dec 9
PTY8:55 amPanama City Tocumen Intl
12h 26m
1 stop
SAN6:21 pmSan Diego
Dec 12
SAN5:23 pmSan Diego
18h 22m
1 stop
PTY2:45 pmPanama City Tocumen Intl
$497
Find similar
United Airlines
Dec 9
PTY11:35 amPanama City Tocumen Intl
11h 17m
2 stops
SAN7:52 pmSan Diego
Dec 12
SAN7:00 pmSan Diego
19h 07m
2 stops
PTY5:07 pmPanama City Tocumen Intl
$501
Find similar

Copa Airlines flights from Panama City to San Diego

Our best Copa Airlines deals on Panama City to San Diego flight tickets
Copa Airlines
Jan 16
PTY1:45 pmPanama City Tocumen Intl
6h 56m
SAN5:41 pmSan Diego
Jan 23
SAN8:16 pmSan Diego
6h 04m
PTY5:20 amPanama City Tocumen Intl
$429
Find similar
Copa Airlines
Jan 23
PTY1:45 pmPanama City Tocumen Intl
6h 56m
SAN5:41 pmSan Diego
Feb 8
SAN8:17 pmSan Diego
6h 03m
PTY5:20 amPanama City Tocumen Intl
$477
Find similar
Copa Airlines
Jan 6
PTY1:45 pmPanama City Tocumen Intl
6h 56m
SAN5:41 pmSan Diego
Jan 9
SAN8:16 pmSan Diego
6h 04m
PTY5:20 amPanama City Tocumen Intl
$568
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 2, 2025.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 1/23

1:45 pm-5:41 pm

Nonstop6h 56m

San Diego

dom. 2/8

8:17 pm-5:20 am

Nonstop6h 03m

$477

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 1/23

4:41 pm-9:20 am

2 stops19h 39m

San Diego

dom. 2/8

4:10 pm-2:45 pm

2 stops19h 35m

$483

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 1/28

4:41 pm-10:46 am

2 stops21h 05m

San Diego

jue. 2/5

4:00 pm-2:45 pm

2 stops19h 45m

$505

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 2/13

4:41 pm-11:14 am

1 stop21h 33m

San Diego

jue. 2/19

3:40 pm-5:07 pm

1 stop22h 27m

$531

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 12/12

11:35 am-11:42 pm

2 stops15h 07m

San Diego

sáb. 1/3

7:40 am-6:49 pm

1 stop32h 09m

$532

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mar. 1/6

1:45 pm-5:41 pm

Nonstop6h 56m

San Diego

vie. 1/9

8:16 pm-5:20 am

Nonstop6h 04m

$568

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 12/14

2:55 am-8:39 am

3 stops32h 44m

San Diego

mié. 12/24

8:12 pm-5:20 am

Nonstop6h 08m

$614

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mar. 1/6

4:41 pm-4:36 pm

1 stop26h 55m

San Diego

vie. 1/9

6:00 pm-5:07 pm

2 stops20h 07m

$693

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 1/23

11:57 am-7:54 pm

1 stop10h 57m

San Diego

dom. 2/8

8:17 pm-5:20 am

Nonstop6h 03m

$709

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

lun. 12/15

3:35 pm-10:40 am

1 stop22h 05m

San Diego

mié. 12/24

3:00 pm-2:45 pm

1 stop20h 45m

$713

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Panama City to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Panama City during the month November is also very affordable. Most momondo users find prices during this month for around $428.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Panama City to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $235. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $668. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $334. Flights in the evening are often more expensive with an average ticket price of $1,009.

What is the cheapest Panama City Tocumen Intl to San Diego flight route?

Fly from Panama City Tocumen Intl to San Diego for the best Panama City Tocumen Intl - San Diego flight prices

What cabin class options are available on Panama City Tocumen Intl to San Diego flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to San Diego flights?

No. A direct flight is the cheapest option for a flight between Panama City to San Diego.

How have Panama City to San Diego flight prices changed over time?

As of December 2025, prices for Panama City to San Diego flights are approximately 29% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to San Diego (PTY to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to San Diego

Best Price Found

$234

Fastest flight time

6h 39m

Direct flights

Mon, Tue, Wed, Thu and Sat

Airports in San Diego

1 airport
The best flight deal from Panama City to San Diego found on momondo in the last 72 hours is $234
The fastest flight from Panama City to San Diego takes 6h 39m
Direct flights go from Panama City to San Diego on Monday, Tuesday, Wednesday, Thursday and Saturday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • How far is Panama City Tocumen Intl to San Diego by plane?

    San Diego is 2903.4 mi away from Panama City Tocumen Intl. 6h 52m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to San Diego Airport?

    Prices for flights from Panama City Tocumen Intl Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to San Diego?

  • What is the most popular airline from Panama City to San Diego?

Best airlines flying from Panama City to San Diego

Compare and see reviews for airlines that fly from Panama City to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $224Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $361Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

  • Copa Airlines Flights From Panama City to San Diego

    Copa Airlines is one of the most popular airlines flying from Panama City to San Diego, operating 1 flight/week on average for this route. A good Copa Airlines flight deal for Panama City to San Diego starts from $224 round-trip, up to an average price of $460. Our users have rated Copa Airlines at 7.6/10.

  • United Airlines Flights From Panama City to San Diego

    $361 is the best United Airlines flight deal from Panama City to San Diego found on momondo over the last 72 hours. The average United Airlines ticket price found was closer to $600, however, with flight time and availability significantly affecting the price. United Airlines (7.4/10 from 9,063 user reviews) flies into San Diego from Panama City 4 times in an average week so prices can vary.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
Poway
La Mesa
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Diego?

Finding the right flight to San Diego from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Panama City to San Diego with flexible booking policies on momondo?

All flight searches from Panama City to San Diego on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to San Diego?

momondo helps you find the best flight between Panama City and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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