Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City, Florida to San Francisco from $193

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Francisco departing on 3/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City, Florida to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:30 pm - 8:33 pm
ECP
-
SFO
9h 03m
1 stop
Delta Logo
2:20 pm - 11:04 pm
SFO
-
ECP
6h 44m
1 stop
$359Delta
Tue, Mar 24 - Wed, Apr 1
Delta Logo
6:43 pm - 12:35 am
ECP
-
SFO
7h 52m
1 stop
Delta Logo
2:20 pm - 11:04 pm
SFO
-
ECP
6h 44m
1 stop
$372Delta
Mon, Mar 23 - Tue, Mar 31
Delta Logo
4:23 pm - 11:19 pm
ECP
-
SFO
8h 56m
1 stop
Delta Logo
2:20 pm - 11:04 pm
SFO
-
ECP
6h 44m
1 stop
$385Delta
Mon, Mar 23 - Wed, Apr 1
Delta Logo
6:00 am - 8:00 pm
ECP
-
SFO
16h 00m
2 stops
Delta Logo
2:20 pm - 11:04 pm
SFO
-
ECP
6h 44m
1 stop
$397Delta
Tue, Mar 24 - Wed, Apr 1
Southwest Logo
3:05 pm - 11:45 pm
ECP
-
SFO
10h 40m
1 stop
Southwest Logo
5:30 am - 3:50 pm
SFO
-
ECP
8h 20m
1 stop
$398Southwest
Tue, Mar 24 - Thu, Apr 2
Southwest Logo
3:30 pm - 12:15 am
ECP
-
SFO
10h 45m
2 stops
Southwest Logo
5:30 am - 3:50 pm
SFO
-
ECP
8h 20m
1 stop
$403Southwest
Tue, Mar 24 - Thu, Apr 2
Southwest Logo
3:30 pm - 12:15 am
ECP
-
SFO
10h 45m
2 stops
Southwest Logo
6:50 am - 5:25 pm
SFO
-
ECP
8h 35m
2 stops
$408Southwest
Tue, Mar 24 - Thu, Apr 2
Delta Logo
1:30 pm - 8:33 pm
ECP
-
SFO
9h 03m
1 stop
Delta Logo
10:35 pm - 8:40 am
SFO
-
ECP
8h 05m
1 stop
$409Delta
Tue, Mar 24 - Sat, Apr 4
Delta Logo
6:43 pm - 12:35 am
ECP
-
SFO
7h 52m
1 stop
Delta Logo
4:03 pm - 8:40 am
SFO
-
ECP
14h 37m
2 stops
$410Delta
Mon, Mar 23 - Tue, Mar 31
Delta Logo
4:23 pm - 11:19 pm
ECP
-
SFO
8h 56m
1 stop
Delta Logo
11:25 pm - 8:40 am
SFO
-
ECP
7h 15m
1 stop
$411Delta
Mon, Mar 23 - Sun, Apr 5

Southwest flights from Panama City, Florida to San Francisco

Our best Southwest deals on Panama City, Florida to San Francisco flight tickets
Southwest
Mar 24
ECP3:05 pmPanama City NW Florida Beaches
10h 40m
1 stop
SFO11:45 pmSan Francisco
Apr 2
SFO5:30 amSan Francisco
8h 20m
1 stop
ECP3:50 pmPanama City NW Florida Beaches
$398
Southwest
Mar 24
ECP7:30 amPanama City NW Florida Beaches
11h 00m
2 stops
SFO4:30 pmSan Francisco
Apr 2
SFO5:30 amSan Francisco
8h 20m
1 stop
ECP3:50 pmPanama City NW Florida Beaches
$403
Southwest
Mar 24
ECP3:30 pmPanama City NW Florida Beaches
10h 45m
2 stops
SFO12:15 amSan Francisco
Apr 2
SFO6:50 amSan Francisco
8h 35m
2 stops
ECP5:25 pmPanama City NW Florida Beaches
$408

Delta flights from Panama City, Florida to San Francisco

Our best Delta deals on Panama City, Florida to San Francisco flight tickets
Delta
Mar 24
ECP1:30 pmPanama City NW Florida Beaches
9h 03m
1 stop
SFO8:33 pmSan Francisco
Apr 1
SFO2:20 pmSan Francisco
6h 44m
1 stop
ECP11:04 pmPanama City NW Florida Beaches
$359
Delta
Mar 23
ECP6:43 pmPanama City NW Florida Beaches
7h 52m
1 stop
SFO12:35 amSan Francisco
Mar 31
SFO2:20 pmSan Francisco
6h 44m
1 stop
ECP11:04 pmPanama City NW Florida Beaches
$372
Delta
Mar 23
ECP6:43 pmPanama City NW Florida Beaches
7h 52m
1 stop
SFO12:35 amSan Francisco
Mar 30
SFO9:35 pmSan Francisco
9h 05m
1 stop
ECP8:40 amPanama City NW Florida Beaches
$385

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Panama City, Florida to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/24

1:30 pm-8:33 pm

1 stop9h 03m

San Francisco

Wed 4/1

2:20 pm-11:04 pm

1 stop6h 44m

$359

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Mon 3/23

6:43 pm-12:35 am

1 stop7h 52m

San Francisco

Tue 3/31

2:20 pm-11:04 pm

1 stop6h 44m

$372

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Mon 3/23

4:23 pm-11:19 pm

1 stop8h 56m

San Francisco

Wed 4/1

2:20 pm-11:04 pm

1 stop6h 44m

$385

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/24

6:00 am-8:00 pm

2 stops16h 00m

San Francisco

Wed 4/1

2:20 pm-11:04 pm

1 stop6h 44m

$397

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/24

3:05 pm-11:45 pm

1 stop10h 40m

San Francisco

Thu 4/2

5:30 am-3:50 pm

1 stop8h 20m

$398

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/24

3:30 pm-12:15 am

2 stops10h 45m

San Francisco

Thu 4/2

5:30 am-3:50 pm

1 stop8h 20m

$403

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/24

3:30 pm-12:15 am

2 stops10h 45m

San Francisco

Thu 4/2

6:50 am-5:25 pm

2 stops8h 35m

$408

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/24

1:30 pm-8:33 pm

1 stop9h 03m

San Francisco

Sat 4/4

10:35 pm-8:40 am

1 stop8h 05m

$409

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Mon 3/23

6:43 pm-12:35 am

1 stop7h 52m

San Francisco

Tue 3/31

4:03 pm-8:40 am

2 stops14h 37m

$410

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Mon 3/23

4:23 pm-11:19 pm

1 stop8h 56m

San Francisco

Sun 4/5

11:25 pm-8:40 am

1 stop7h 15m

$411

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Panama City, Florida to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of April, then flying in June is also cheap. Prices for this month can be found on momondo for an average of $389.

How have Panama City, Florida to San Francisco flight prices changed over time?

As of February 2026, prices for Panama City, Florida to San Francisco flights are approximately 94% more expensive when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Francisco (ECP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Francisco

Fastest flight time

7h 57m

Direct flights

None
The fastest flight from Panama City, Florida to San Francisco takes 7h 57m
There are no direct flights from Panama City, Florida to San Francisco. There are no popular flight routes from Panama City, Florida to San Francisco.
Search flight deals

  • How far is Panama City NW Florida Beaches to San Francisco by plane?

    Panama City NW Florida Beaches and San Francisco are 2154.5 mi apart from one another. A reasonable flight in good conditions will take 7h 57m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Francisco Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Francisco Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Francisco?

Best airlines flying from Panama City, Florida to San Francisco

Compare and see reviews for airlines that fly from Panama City, Florida to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $297Free CancellationRating
7.9
8,207 reviews
Search Delta flights
United AirlinesPriceFrom $306Free CancellationRating
7.4
9,312 reviews
Search United Airlines flights
American AirlinesPriceFrom $360Free CancellationRating
7.2
11,304 reviews
Search American Airlines flights
SouthwestPriceFrom $389Free CancellationRating
8.0
4,294 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Walnut Creek
Santa Clara
Calistoga
Berkeley
Big Sur
Fremont
Daly City
Half Moon Bay
Salinas
Vallejo
Sunnyvale
Milpitas
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to San Francisco for you.

Can I find flights from Panama City to San Francisco with flexible booking policies on momondo?

All flight searches from Panama City to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 3/19
Thu 3/26
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States