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Cheap flights from Panama City, Florida to San Francisco from $198

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to San Francisco departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City, Florida to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
10:30 am - 7:05 pm
ECP
-
SFO
10h 35m
2 stops
Southwest Logo
6:35 am - 6:45 pm
SFO
-
ECP
10h 10m
2 stops
$341Southwest
Tue, Sep 29 - Wed, Sep 30
Southwest Logo
10:30 am - 6:40 pm
ECP
-
SFO
10h 10m
1 stop
Southwest Logo
11:05 pm - 1:15 pm
SFO
-
ECP
12h 10m
1 stop
$342Southwest
Tue, Sep 29 - Wed, Sep 30
Delta Logo
5:30 pm - 11:57 pm
ECP
-
SFO
8h 27m
1 stop
Delta Logo
9:30 pm - 8:17 am
SFO
-
ECP
8h 47m
1 stop
$355Delta
Sat, Sep 19 - Mon, Oct 26
Southwest Logo
4:10 pm - 9:55 pm
ECP
-
SFO
7h 45m
1 stop
Southwest Logo
11:05 pm - 9:25 am
SFO
-
ECP
8h 20m
1 stop
$380Southwest
Thu, Sep 3 - Sun, Sep 6
Southwest Logo
4:10 pm - 9:55 pm
ECP
-
SFO
7h 45m
1 stop
Southwest Logo
8:20 am - 8:35 pm
SFO
-
ECP
10h 15m
2 stops
$385Southwest
Thu, Sep 3 - Sun, Sep 6
United Airlines Logo
11:41 am - 4:57 pm
ECP
-
SFO
7h 16m
1 stop
United Airlines Logo
5:00 am - 4:13 pm
SFO
-
ECP
9h 13m
1 stop
$397United Airlines
Wed, Sep 23 - Sat, Sep 26
American Airlines Logo
7:28 am - 2:58 pm
ECP
-
SFO
9h 30m
1 stop
American Airlines Logo
8:45 am - 5:33 pm
SFO
-
ECP
6h 48m
1 stop
$401American Airlines
Wed, Jul 22 - Sat, Aug 29
Delta Logo
6:00 am - 11:59 am
ECP
-
SFO
7h 59m
1 stop
Delta Logo
10:30 pm - 10:15 am
SFO
-
ECP
9h 45m
1 stop
$405Delta
Tue, Oct 27 - Tue, Nov 10
American Airlines Logo
3:13 pm - 9:10 pm
ECP
-
SFO
7h 57m
1 stop
American Airlines Logo
8:45 am - 5:33 pm
SFO
-
ECP
6h 48m
1 stop
$410American Airlines
Wed, Jul 22 - Sat, Aug 29
Delta Logo
5:30 pm - 11:57 pm
ECP
-
SFO
8h 27m
1 stop
Delta Logo
9:30 pm - 8:17 am
SFO
-
ECP
8h 47m
1 stop
$418Delta
Sat, Sep 19 - Mon, Oct 26

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American Airlines flights from Panama City, Florida to San Francisco

Our best American Airlines deals on Panama City, Florida to San Francisco flight tickets
American Airlines
Jul 22
ECP7:28 amPanama City NW Florida Beaches
9h 30m
1 stop
SFO2:58 pmSan Francisco
Aug 29
SFO8:45 amSan Francisco
6h 48m
1 stop
ECP5:33 pmPanama City NW Florida Beaches
$401
American Airlines
Jul 22
ECP3:13 pmPanama City NW Florida Beaches
7h 57m
1 stop
SFO9:10 pmSan Francisco
Aug 29
SFO8:45 amSan Francisco
6h 48m
1 stop
ECP5:33 pmPanama City NW Florida Beaches
$410
American Airlines
Jul 3
ECP4:17 pmPanama City NW Florida Beaches
8h 31m
1 stop
SFO10:48 pmSan Francisco
Jul 5
SFO1:05 amSan Francisco
6h 29m
1 stop
ECP9:34 amPanama City NW Florida Beaches
$426

Delta flights from Panama City, Florida to San Francisco

Our best Delta deals on Panama City, Florida to San Francisco flight tickets
Delta
Oct 27
ECP6:00 amPanama City NW Florida Beaches
7h 59m
1 stop
SFO11:59 amSan Francisco
Nov 10
SFO10:30 pmSan Francisco
9h 45m
1 stop
ECP10:15 amPanama City NW Florida Beaches
$405
Delta
Sep 19
ECP5:30 pmPanama City NW Florida Beaches
8h 27m
1 stop
SFO11:57 pmSan Francisco
Oct 26
SFO9:30 pmSan Francisco
8h 47m
1 stop
ECP8:17 amPanama City NW Florida Beaches
$418
Delta
Oct 27
ECP1:30 pmPanama City NW Florida Beaches
8h 07m
1 stop
SFO7:37 pmSan Francisco
Nov 12
SFO9:30 pmSan Francisco
8h 47m
1 stop
ECP8:17 amPanama City NW Florida Beaches
$420

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Panama City, Florida to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 9/29

10:30 am-7:05 pm

2 stops10h 35m

San Francisco

Wed 9/30

6:35 am-6:45 pm

2 stops10h 10m

$341

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 9/29

10:30 am-6:40 pm

1 stop10h 10m

San Francisco

Wed 9/30

11:05 pm-1:15 pm

1 stop12h 10m

$342

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Sat 9/19

5:30 pm-11:57 pm

1 stop8h 27m

San Francisco

Mon 10/26

9:30 pm-8:17 am

1 stop8h 47m

$355

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Thu 9/3

4:10 pm-9:55 pm

1 stop7h 45m

San Francisco

Sun 9/6

11:05 pm-9:25 am

1 stop8h 20m

$380

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Thu 9/3

4:10 pm-9:55 pm

1 stop7h 45m

San Francisco

Sun 9/6

8:20 am-8:35 pm

2 stops10h 15m

$385

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Wed 9/23

11:41 am-4:57 pm

1 stop7h 16m

San Francisco

Sat 9/26

5:00 am-4:13 pm

1 stop9h 13m

$397

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Wed 7/22

7:28 am-2:58 pm

1 stop9h 30m

San Francisco

Sat 8/29

8:45 am-5:33 pm

1 stop6h 48m

$401

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 10/27

6:00 am-11:59 am

1 stop7h 59m

San Francisco

Tue 11/10

10:30 pm-10:15 am

1 stop9h 45m

$405
Quickest round-trip

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Wed 7/22

3:13 pm-9:10 pm

1 stop7h 57m

San Francisco

Sat 8/29

8:45 am-5:33 pm

1 stop6h 48m

$410

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Sat 9/19

5:30 pm-11:57 pm

1 stop8h 27m

San Francisco

Mon 10/26

9:30 pm-8:17 am

1 stop8h 47m

$418

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Panama City, Florida to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of January, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $424.

How have Panama City, Florida to San Francisco flight prices changed over time?

As of June 2026, prices for Panama City, Florida to San Francisco flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Francisco (ECP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Francisco

Fastest flight time

7h 16m

Direct flights

None
The fastest flight from Panama City, Florida to San Francisco takes 7h 16m
There are no direct flights from Panama City, Florida to San Francisco. There are no popular flight routes from Panama City, Florida to San Francisco.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to San Francisco

  • How far is Panama City NW Florida Beaches to San Francisco by plane?

    Panama City NW Florida Beaches and San Francisco are 2153.9 mi apart from one another. A reasonable flight in good conditions will take 7h 16m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Francisco Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Francisco Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Francisco?

Best airlines flying from Panama City, Florida to San Francisco

Compare and see reviews for airlines that fly from Panama City, Florida to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $297Free CancellationRating
7.9
8,394 reviews
Search Delta flights
United AirlinesPriceFrom $306Free CancellationRating
7.4
9,796 reviews
Search United Airlines flights
American AirlinesPriceFrom $358Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
SouthwestPriceFrom $445Free CancellationRating
7.9
4,240 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Hayward
Roseville
Bodega Bay
Walnut Creek
Santa Clara
Berkeley
Fremont
Vallejo
Sunnyvale
Big Sur
South San Francisco
Pacific Grove
Daly City
Burlingame
Calistoga
Salinas

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to San Francisco for you.

Can I find flights from Panama City to San Francisco with flexible booking policies on momondo?

All flight searches from Panama City to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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