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Cheap flights from Panama City, Florida to San Francisco from $189

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City, Florida to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:07 pm - 11:57 pmECP  Panama City NW Florida Beaches-SFO San Francisco
9h 50m1 stop Dallas/Fort Worth
American Airlines Logo
12:16 pm - 10:40 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
8h 24m1 stop Charlotte Douglas
$377American Airlines
Tue, Oct 20 - Tue, Oct 27
Southwest Logo
7:40 am - 3:10 pmECP  Panama City NW Florida Beaches-SFO San Francisco
9h 30m1 stop Nashville Intl
Southwest Logo
6:55 am - 6:25 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
9h 30m2 stops Las Vegas Harry Reid Intl Nashville Intl
$398Southwest
Tue, Oct 20 - Tue, Oct 27
Southwest Logo
7:40 am - 4:05 pmECP  Panama City NW Florida Beaches-SFO San Francisco
10h 25m2 stops Nashville Intl Denver Intl
Southwest Logo
6:55 am - 6:25 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
9h 30m2 stops Las Vegas Harry Reid Intl Nashville Intl
$403Southwest
Tue, Oct 20 - Tue, Oct 27
Delta Logo
9:30 am - 5:16 pmECP  Panama City NW Florida Beaches-SFO San Francisco
9h 46m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:59 pm - 8:38 amSFO  San Francisco-ECP Panama City NW Florida Beaches
7h 39m1 stop Atlanta Hartsfield-Jackson
$409Delta
Fri, Nov 13 - Fri, Dec 4
American Airlines Logo
12:13 pm - 6:28 pmECP  Panama City NW Florida Beaches-SFO San Francisco
8h 15m1 stop Dallas/Fort Worth
American Airlines Logo
6:38 am - 3:10 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
6h 32m1 stop Dallas/Fort Worth
$409American Airlines
Fri, Nov 13 - Fri, Dec 4
American Airlines Logo
7:36 am - 2:44 pmECP  Panama City NW Florida Beaches-SFO San Francisco
9h 08m1 stop Charlotte Douglas
American Airlines Logo
8:00 am - 6:31 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
8h 31m1 stop Charlotte Douglas
$409American Airlines
Fri, Dec 25 - Fri, Jan 1
Southwest Logo
3:00 pm - 11:55 pmECP  Panama City NW Florida Beaches-SFO San Francisco
10h 55m2 stops Dallas Love Field Phoenix Sky Harbor Intl
Southwest Logo
9:40 pm - 10:30 amSFO  San Francisco-ECP Panama City NW Florida Beaches
10h 50m2 stops Las Vegas Harry Reid Intl Dallas Love Field
$469Southwest
Wed, Dec 23 - Tue, Dec 29
Delta Logo
9:30 am - 8:17 pmECP  Panama City NW Florida Beaches-SFO San Francisco
12h 47m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl
Delta Logo
10:59 pm - 10:34 amSFO  San Francisco-ECP Panama City NW Florida Beaches
9h 35m1 stop Atlanta Hartsfield-Jackson
$491Delta
Fri, Nov 13 - Fri, Dec 4
United Airlines Logo
9:06 am - 5:10 pmECP  Panama City NW Florida Beaches-SFO San Francisco
10h 04m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 am - 2:28 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
7h 28m1 stop Houston George Bush Intcntl
$507United Airlines
Tue, Nov 10 - Wed, Nov 11
United Airlines Logo
9:06 am - 5:10 pmECP  Panama City NW Florida Beaches-SFO San Francisco
10h 04m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 am - 2:28 pmSFO  San Francisco-ECP Panama City NW Florida Beaches
7h 28m1 stop Houston George Bush Intcntl
$543United Airlines
Tue, Nov 10 - Wed, Nov 11

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American Airlines flights from Panama City, Florida to San Francisco

Our best American Airlines deals on Panama City, Florida to San Francisco flight tickets
American Airlines
Oct 20
ECP4:07 pmPanama City NW Florida Beaches
9h 50m
1 stop
SFO11:57 pmSan Francisco
Oct 27
SFO12:16 pmSan Francisco
8h 24m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
$377
American Airlines
Dec 1
ECP7:25 amPanama City NW Florida Beaches
9h 29m
1 stop
SFO2:54 pmSan Francisco
Dec 6
SFO5:35 amSan Francisco
7h 38m
1 stop
ECP3:13 pmPanama City NW Florida Beaches
$459
American Airlines
Dec 25
ECP4:31 pmPanama City NW Florida Beaches
7h 46m
1 stop
SFO10:17 pmSan Francisco
Jan 1
SFO8:00 amSan Francisco
8h 32m
1 stop
ECP6:32 pmPanama City NW Florida Beaches
$464

Southwest flights from Panama City, Florida to San Francisco

Our best Southwest deals on Panama City, Florida to San Francisco flight tickets
Southwest
Oct 20
ECP7:40 amPanama City NW Florida Beaches
9h 30m
1 stop
SFO3:10 pmSan Francisco
Oct 27
SFO6:55 amSan Francisco
9h 30m
2 stops
ECP6:25 pmPanama City NW Florida Beaches
$398
Southwest
Oct 20
ECP7:40 amPanama City NW Florida Beaches
10h 25m
2 stops
SFO4:05 pmSan Francisco
Oct 27
SFO6:55 amSan Francisco
9h 30m
2 stops
ECP6:25 pmPanama City NW Florida Beaches
$403
Southwest
Dec 23
ECP3:00 pmPanama City NW Florida Beaches
10h 55m
2 stops
SFO11:55 pmSan Francisco
Dec 29
SFO9:40 pmSan Francisco
10h 50m
2 stops
ECP10:30 amPanama City NW Florida Beaches
$469

momondo Fare Finder

 
Use the filters below to find and compare flights from Panama City, Florida to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Tue 10/20

4:07 pm-11:57 pm

1 stop9h 50m

San Francisco

Tue 10/27

12:16 pm-10:40 pm

1 stop8h 24m

$377

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Tue 10/20

7:40 am-3:10 pm

1 stop9h 30m

San Francisco

Tue 10/27

6:55 am-6:25 pm

2 stops9h 30m

$398

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Tue 10/20

7:40 am-4:05 pm

2 stops10h 25m

San Francisco

Tue 10/27

6:55 am-6:25 pm

2 stops9h 30m

$403

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Fri 11/13

9:30 am-5:16 pm

1 stop9h 46m

San Francisco

Fri 12/4

10:59 pm-8:38 am

1 stop7h 39m

$409
Quickest round-trip

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Fri 11/13

12:13 pm-6:28 pm

1 stop8h 15m

San Francisco

Fri 12/4

6:38 am-3:10 pm

1 stop6h 32m

$409

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Fri 12/25

7:36 am-2:44 pm

1 stop9h 08m

San Francisco

Fri 1/1

8:00 am-6:31 pm

1 stop8h 31m

$409

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Wed 12/23

3:00 pm-11:55 pm

2 stops10h 55m

San Francisco

Tue 12/29

9:40 pm-10:30 am

2 stops10h 50m

$469

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Fri 11/13

9:30 am-8:17 pm

2 stops12h 47m

San Francisco

Fri 12/4

10:59 pm-10:34 am

1 stop9h 35m

$491

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Tue 11/10

9:06 am-5:10 pm

1 stop10h 04m

San Francisco

Wed 11/11

5:00 am-2:28 pm

1 stop7h 28m

$507

Panama CitySan Francisco

ECP Panama City NW Florida Beaches - SFO San Francisco

ECPSFO

Panama City NW Florida Beaches

Tue 11/10

9:06 am-5:10 pm

1 stop10h 04m

San Francisco

Wed 11/11

5:00 am-2:28 pm

1 stop7h 28m

$543

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City, Florida to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $397 to $637.
The lowest price recently found on this route was $377.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $402.

How have Panama City, Florida to San Francisco flight prices changed over time?

As of September 2026, prices for Panama City, Florida to San Francisco flights are approximately 45% cheaper when compared to flights at the same time last year.

When to book flights from Panama City, Florida to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to San Francisco (ECP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to San Francisco

Best Price Found

$189

Fastest flight time

7h 36m

Direct flights

None
The best one-way flight to San Francisco from Panama City, Florida in the past 72 hours is $189. The best round-trip flight deal from Panama City, Florida to San Francisco found on momondo in the last 72 hours is $377.
The fastest flight from Panama City, Florida to San Francisco takes 7h 36m
There are no direct flights from Panama City, Florida to San Francisco. There are no popular flight routes from Panama City, Florida to San Francisco.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to San Francisco

  • How far is Panama City NW Florida Beaches to San Francisco by plane?

    Panama City NW Florida Beaches and San Francisco are 2153.9 mi apart from one another. A reasonable flight in good conditions will take 7h 36m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to San Francisco Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to San Francisco Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to San Francisco?

Best airlines flying from Panama City, Florida to San Francisco

Compare and see reviews for airlines that fly from Panama City, Florida to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $297Free CancellationRating
7.8
8,608 reviews
Search Delta flights
SouthwestPriceFrom $354Free CancellationRating
8.0
4,204 reviews
Search Southwest flights
United AirlinesPriceFrom $371Free CancellationRating
7.4
10,261 reviews
Search United Airlines flights
American AirlinesPriceFrom $393Free CancellationRating
7.0
12,097 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Hayward
Berkeley
Bodega Bay
Fremont
Walnut Creek
Santa Clara
Sunnyvale
Vallejo
Half Moon Bay
Roseville
Salinas
Sonoma
Milpitas
Daly City
Pacific Grove
Palo Alto

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to San Francisco for you.

Can I find flights from Panama City to San Francisco with flexible booking policies on momondo?

All flight searches from Panama City to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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