Cheap flights from Chicago O'Hare Intl Airport to San Antonio from $85

If you aren’t able to travel during the month of August, then book flights to San Antonio from Chicago O'Hare Intl Airport during September instead. Flights to San Antonio in September, while not as cheap as those in August, still average around $333.

The cheapest day to depart on your flight to San Antonio is on a Tuesday when prices can be found for as low as $358. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to San Antonio on Sunday is $446.

According to our data, the cheapest time of day to fly to San Antonio is at noon. momondo users have found flights departing from Chicago O'Hare Intl Airport to San Antonio at noon for as low as $386. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to San Antonio are more costly in the afternoon, with an average ticket price of $397. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Chicago O'Hare Intl to San Antonio for the best Chicago O'Hare Intl - San Antonio flight prices

You are more likely to see cheaper flights to San Antonio from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $374 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from Chicago O'Hare Intl Airport for as low as $322 on momondo.

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to San Antonio flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 11% on your flight if you consider stops on a Chicago O'Hare Intl Airport to San Antonio flight.

As of February 2026, prices for Chicago O'Hare Intl Airport to San Antonio flights are approximately 25% cheaper when compared to flights at the same time last year.

Spirit Airlines and United Airlines are the most popular carriers operating from Chicago O'Hare Intl to San Antonio

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to San Antonio from Chicago O'Hare Intl Airport according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to San Antonio. Keep in mind that there are 5 different airlines that fly to San Antonio on a routine basis, so you have a few additional options to choose from.

As of February 2026, 16 flights take off from Chicago O'Hare Intl Airport and land in San Antonio each day. The most common flight departure time for this route is 8:00PM, with 61% of daily flights taking off in the evening.

118 flights are operational weekly from Chicago O'Hare Intl Airport to San Antonio as of February 2026. The most popular departure day for this route is Fri, with 19% of flights per week taking off on this day.