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Cheap flights from Myrtle Beach to San Francisco from $292

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 6/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
2:10 pm - 10:10 pm
MYR
-
STS
11h 00m
2 stops
Southwest Logo
2:15 pm - 9:50 am
STS
-
MYR
16h 35m
2 stops
$605Southwest
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
6:33 am - 12:03 pm
MYR
-
STS
8h 30m
1 stop
American Airlines Logo
12:45 pm - 11:51 pm
STS
-
MYR
8h 06m
1 stop
$617American Airlines
Tue, Jun 2 - Tue, Jun 9
Southwest Logo
2:10 pm - 10:10 pm
MYR
-
STS
11h 00m
2 stops
Southwest Logo
4:15 pm - 10:05 am
STS
-
MYR
14h 50m
2 stops
$724Southwest
Wed, May 20 - Sun, May 24
Southwest Logo
10:55 am - 10:40 pm
MYR
-
STS
14h 45m
2 stops
Southwest Logo
4:35 pm - 10:35 am
STS
-
MYR
15h 00m
2 stops
$841Southwest
Fri, May 22 - Tue, May 26
American Airlines Logo
6:33 am - 12:03 pm
MYR
-
STS
8h 30m
1 stop
American Airlines Logo
12:43 pm - 11:51 pm
STS
-
MYR
8h 08m
1 stop
$916American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
6:33 am - 12:03 pm
MYR
-
STS
8h 30m
1 stop
American Airlines Logo
12:43 pm - 11:51 pm
STS
-
MYR
8h 08m
1 stop
$927American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
6:33 am - 12:03 pm
MYR
-
STS
8h 30m
1 stop
American Airlines Logo
4:20 pm - 8:44 am
STS
-
MYR
13h 24m
2 stops
$983American Airlines
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
6:04 am - 3:53 pm
MYR
-
STS
12h 49m
2 stops
American Airlines Logo
12:43 pm - 11:51 pm
STS
-
MYR
8h 08m
1 stop
$1,041American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
6:50 am - 3:50 pm
MYR
-
STS
12h 00m
2 stops
American Airlines Logo
12:43 pm - 11:51 pm
STS
-
MYR
8h 08m
1 stop
$1,088American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
6:33 am - 12:03 pm
MYR
-
STS
8h 30m
1 stop
American Airlines Logo
4:20 pm - 8:44 am
STS
-
MYR
13h 24m
2 stops
$1,126American Airlines
Fri, May 22 - Tue, May 26

Southwest flights from Myrtle Beach to Santa Rosa

Our best Southwest deals on Myrtle Beach to Santa Rosa flight tickets
Southwest
Jun 2
MYR2:10 pmMyrtle Beach Intl
11h 00m
2 stops
STS10:10 pmSanta Rosa Sonoma County
Jun 9
STS2:15 pmSanta Rosa Sonoma County
16h 35m
2 stops
MYR9:50 amMyrtle Beach Intl
$605
Southwest
May 20
MYR2:10 pmMyrtle Beach Intl
11h 00m
2 stops
STS10:10 pmSanta Rosa Sonoma County
May 24
STS4:15 pmSanta Rosa Sonoma County
14h 50m
2 stops
MYR10:05 amMyrtle Beach Intl
$724
Southwest
May 22
MYR10:55 amMyrtle Beach Intl
14h 45m
2 stops
STS10:40 pmSanta Rosa Sonoma County
May 26
STS4:35 pmSanta Rosa Sonoma County
15h 00m
2 stops
MYR10:35 amMyrtle Beach Intl
$841

American Airlines flights from Myrtle Beach to Santa Rosa

Our best American Airlines deals on Myrtle Beach to Santa Rosa flight tickets
American Airlines
Jun 2
MYR6:33 amMyrtle Beach Intl
8h 30m
1 stop
STS12:03 pmSanta Rosa Sonoma County
Jun 9
STS12:45 pmSanta Rosa Sonoma County
8h 06m
1 stop
MYR11:51 pmMyrtle Beach Intl
$617
American Airlines
May 22
MYR6:33 amMyrtle Beach Intl
8h 30m
1 stop
STS12:03 pmSanta Rosa Sonoma County
May 26
STS12:43 pmSanta Rosa Sonoma County
8h 08m
1 stop
MYR11:51 pmMyrtle Beach Intl
$916
American Airlines
May 22
MYR6:33 amMyrtle Beach Intl
8h 30m
1 stop
STS12:03 pmSanta Rosa Sonoma County
May 26
STS12:43 pmSanta Rosa Sonoma County
8h 08m
1 stop
MYR11:51 pmMyrtle Beach Intl
$927

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santa Rosa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santa Rosa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Tue 6/2

2:10 pm-10:10 pm

2 stops11h 00m

Santa Rosa Sonoma County

Tue 6/9

2:15 pm-9:50 am

2 stops16h 35m

$605
Quickest round-trip

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Tue 6/2

6:33 am-12:03 pm

1 stop8h 30m

Santa Rosa Sonoma County

Tue 6/9

12:45 pm-11:51 pm

1 stop8h 06m

$617

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Wed 5/20

2:10 pm-10:10 pm

2 stops11h 00m

Santa Rosa Sonoma County

Sun 5/24

4:15 pm-10:05 am

2 stops14h 50m

$724

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Fri 5/22

10:55 am-10:40 pm

2 stops14h 45m

Santa Rosa Sonoma County

Tue 5/26

4:35 pm-10:35 am

2 stops15h 00m

$841

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Fri 5/22

6:33 am-12:03 pm

1 stop8h 30m

Santa Rosa Sonoma County

Tue 5/26

12:43 pm-11:51 pm

1 stop8h 08m

$916

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Fri 5/22

6:33 am-12:03 pm

1 stop8h 30m

Santa Rosa Sonoma County

Tue 5/26

12:43 pm-11:51 pm

1 stop8h 08m

$927

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Tue 6/2

6:33 am-12:03 pm

1 stop8h 30m

Santa Rosa Sonoma County

Tue 6/9

4:20 pm-8:44 am

2 stops13h 24m

$983

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Wed 5/20

6:04 am-3:53 pm

2 stops12h 49m

Santa Rosa Sonoma County

Sun 5/24

12:43 pm-11:51 pm

1 stop8h 08m

$1,041

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Fri 5/22

6:50 am-3:50 pm

2 stops12h 00m

Santa Rosa Sonoma County

Tue 5/26

12:43 pm-11:51 pm

1 stop8h 08m

$1,088

Myrtle BeachSanta Rosa

MYR - STS

MYRSTS

Myrtle Beach Intl

Fri 5/22

6:33 am-12:03 pm

1 stop8h 30m

Santa Rosa Sonoma County

Tue 5/26

4:20 pm-8:44 am

2 stops13h 24m

$1,126

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Myrtle Beach to Santa Rosa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Santa Rosa Sonoma County?

American Airlines and Southwest are the most popular carriers operating from Myrtle Beach Intl to Santa Rosa Sonoma County

What airlines fly to Santa Rosa?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Santa Rosa from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Santa Rosa. Keep in mind that there are 6 different airlines that fly to Santa Rosa on a routine basis, so you have a few additional options to choose from.

When to book flights from Myrtle Beach to Santa Rosa

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santa Rosa according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santa Rosa (MYR to STS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santa Rosa

Fastest flight time

8h 30m

Direct flights

None
The fastest flight from Myrtle Beach to Santa Rosa takes 8h 30m
There are no direct flights from Myrtle Beach to Santa Rosa. There are no popular flight routes from Myrtle Beach to Santa Rosa.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Santa Rosa

  • How far is Myrtle Beach Intl to Santa Rosa Sonoma County by plane?

    A flight from Myrtle Beach Intl to Santa Rosa Sonoma County will travel around 2445.0 mi. A reasonable flight in good conditions will take 8h 30m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santa Rosa Sonoma County Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santa Rosa Sonoma County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santa Rosa Sonoma County Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Santa Rosa Sonoma County Airport.

  • What documentation or ID do you need to fly to Santa Rosa Sonoma County Airport?

    The travel and health documents required for your trip to Santa Rosa Sonoma County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Rosa Sonoma County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Fort Bragg
Mendocino
Ukiah
Little River
Point Arena

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santa Rosa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Myrtle Beach to Santa Rosa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Myrtle Beach to Santa Rosa with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Rosa from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Santa Rosa?

momondo provides multiple filters to help you find the best flight to Santa Rosa from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Santa Rosa right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Rosa from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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