Cheap flights from Detroit to San Francisco from $222
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to San Francisco departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Sun 12/13
7:34 pm-12:50 am
1 stop8h 16m
San Francisco
Fri 1/8
6:30 pm-5:42 am
1 stop8h 12m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Mon 12/14
7:34 pm-12:50 am
1 stop8h 16m
San Francisco
Fri 1/8
6:30 pm-5:42 am
1 stop8h 12m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Thu 12/3
6:30 am-11:10 am
1 stop7h 40m
San Francisco
Tue 3/9
6:35 am-4:05 pm
1 stop6h 30m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Thu 12/17
6:10 am-10:30 am
1 stop7h 20m
San Francisco
Sun 1/10
6:05 am-3:55 pm
1 stop6h 50m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Fri 11/6
7:59 pm-10:43 am
1 stop17h 44m
San Francisco
Thu 11/12
10:23 pm-4:55 am
1 stop27h 32m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Sat 1/16
7:25 am-9:27 pm
2 stops17h 02m
San Francisco
Tue 1/19
7:00 pm-4:32 pm
2 stops18h 32m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Tue 2/9
8:20 pm-10:39 pm
Nonstop5h 19m
San Francisco
Sun 2/28
10:45 pm-6:20 am
Nonstop4h 35m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Thu 10/29
8:35 pm-10:38 pm
Nonstop5h 03m
San Francisco
Wed 11/4
10:35 pm-6:04 am
Nonstop4h 29m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Fri 11/6
8:15 am-10:46 am
Nonstop5h 31m
San Francisco
Sun 11/8
11:00 pm-6:42 am
Nonstop4h 42m
DetroitSan Francisco
DTW Detroit Metropolitan Wayne County - SFO San Francisco
DTWSFO
Detroit Metropolitan Wayne County
Mon 11/23
8:15 am-10:46 am
Nonstop5h 31m
San Francisco
Fri 11/27
8:31 am-4:03 pm
Nonstop4h 32m
See travel insights to San Francisco from
How to get the cheapest flight ticket from Detroit to San Francisco
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Detroit and San Francisco?
Prices are currently low for flights on this route.
Typical prices usually range from $359 to $544.The lowest price recently found on this route was $320.
What is the cheapest month to fly to San Francisco?
If you aren’t able to travel to San Francisco during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $421.
What is the cheapest day to depart on your flight to San Francisco?
The cheapest day to depart from Detroit to San Francisco is on a Thursday when prices can be found for as low as $492. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $678.
What is the cheapest time of day to depart on your flight to San Francisco?
Our data shows that the cheapest Detroit to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $500. Flights in the afternoon are often more expensive with an average ticket price of $588.
What is the cheapest Detroit to San Francisco flight route?
Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit - San Francisco flight prices
How far in advance should I book a flight from Detroit to San Francisco?
You are more likely to see cheaper flights to San Francisco from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $460 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit for as low as $370 on momondo.
What cabin class options are available on Detroit to San Francisco flights?
There are 4 cabin classes available to choose from on Detroit to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
What is the cheapest airline that flies from Detroit to San Francisco?
Alaska Airlines, Southwest, and United Airlines are the most popular carriers operating from Detroit to San Francisco
What airlines fly to San Francisco?
Delta, United Airlines and Southwest are the top three most popular airlines that fly to San Francisco from Detroit according to our data. Delta is the first choice among our users, with 47% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.
Which airport is the most popular layover for flights between Detroit and San Francisco?
Denver (DEN) was the most common stop: 55% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from Detroit to San Francisco?
Flights via Denver (DEN) offer the lowest average round-trip price of $227.
Which layover airport has the shortest travel time from Detroit to San Francisco?
Flights connecting via St. Louis (STL) have the shortest average one-way travel time: 6h 40m.
Which layover airport has the shortest connection time from Detroit to San Francisco?
St. Louis (STL) has the shortest average layover time for this route: 1h 10m.
How many flights depart from Detroit to San Francisco on average per day?
As of October 2026, there are 14 flights per day flying from Detroit to San Francisco. The most common time of day flights depart is 7:00PM, with 35% of flights taking off at noon.
How many flights depart from Detroit to San Francisco on average per week?
101 flights are operational weekly from Detroit to San Francisco as of October 2026. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.
When to book flights from Detroit to San Francisco
Cheap Detroit to San Francisco (DTT to SFO) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Detroit to San Francisco
Frequently asked questions about flying from Detroit to San Francisco
How far is Detroit to San Francisco by plane?
A flight from Detroit to San Francisco will travel around 2084.3 mi. Typically, this will take 4h 56m by plane in normal conditions.
When did momondo last update prices for flights from Detroit to San Francisco Airport?
Prices for flights from Detroit to San Francisco Airport are updated daily.
How many operators does momondo search for flights from Detroit to San Francisco Airport?
As of October 2026, there are 6 operators available to choose from for flights from Detroit to San Francisco Airport.
How old do you have to be to fly from Detroit to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Detroit to San Francisco?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Detroit to San Francisco is Boeing 737-900 (32.35% of total bookings). The next most popular plane models are Boeing 757 (13.92%), Airbus A319 (12.27%), and Airbus A320-100/200 (9.83%).
What is the most popular airline from Detroit to San Francisco?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Detroit to San Francisco is Delta (47% of total bookings). The next most popular airlines are United Airlines (37%), Frontier (10%), and American Airlines (3%).
Best airlines flying from Detroit to San Francisco
Compare and see reviews for airlines that fly from Detroit to San Francisco with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $187 | Free Cancellation | Rating 5.6 2,550 reviews | |||
| PriceFrom $259 | Free Cancellation | Rating 7.1 3,049 reviews | |||
| PriceFrom $289 | Free Cancellation | Rating 7.4 10,319 reviews | |||
| PriceFrom $290 | Free Cancellation | Rating 7.9 4,221 reviews | |||
| PriceFrom $308 | Free Cancellation | Rating 7.0 12,145 reviews | |||
| PriceFrom $349 | Free Cancellation | Rating 7.8 8,645 reviews |
Delta Flights From Detroit to San Francisco
The lowest priced Delta flight from Detroit to San Francisco from the last 72 hours was $349. Generally, Delta has 24 flights on this route every week with an average price of $581. Delta is rated 7.8/10 by our users.
United Airlines Flights From Detroit to San Francisco
United Airlines is also a popular choice for this route. United Airlines flight deals for Detroit to San Francisco start from as low as $289 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $426. United Airlines operates 8 flights to San Francisco from Detroit in an average week. Users have rated it 7.4/10 across 10,319 reviews.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Detroit to San Francisco?
momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to San Francisco. Millions of users trust and use momondo every year so you are in good hands.
Can I find flights from Detroit to San Francisco with flexible booking policies on momondo?
momondo does allow users to show only those flights to San Francisco from Detroit which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from Detroit to San Francisco?
momondo helps you find the best flight between Detroit and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.
I’m not ready to book a flight from Detroit to San Francisco right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to San Francisco from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.