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Cheap flights from Detroit to San Francisco from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to San Francisco departing on 3/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:24 am - 8:30 am
DTW
-
SFO
5h 06mnonstop
United Airlines Logo
9:25 pm - 5:15 am
SFO
-
DTW
4h 50mnonstop
$289United Airlines
Fri, May 29 - Tue, Jun 2
Frontier Logo
10:27 pm - 9:08 am
DTW
-
SFO
13h 41m
1 stop
Frontier Logo
6:00 am - 9:41 pm
SFO
-
DTW
12h 41m
1 stop
$290Frontier
Sun, Apr 19 - Thu, May 7
Frontier Logo
5:21 pm - 12:28 am
DTW
-
SFO
10h 07m
1 stop
Frontier Logo
9:04 pm - 10:59 am
SFO
-
DTW
10h 55m
1 stop
$291Frontier
Sat, Feb 28 - Tue, Mar 17
Multiple Airlines Logo
6:00 am - 12:28 am
DTW
-
SFO
21h 28m
1 stop
Multiple Airlines Logo
10:38 pm - 2:57 pm
SFO
-
DTW
13h 19m
1 stop
$292Multiple Airlines
Fri, Feb 27 - Sat, Mar 7
Multiple Airlines Logo
4:55 pm - 9:58 am
DTW
-
SFO
20h 03m
2 stops
Multiple Airlines Logo
10:38 pm - 11:31 am
SFO
-
DTW
9h 53m
1 stop
$293Multiple Airlines
Tue, Apr 21 - Tue, May 5
Multiple Airlines Logo
6:02 pm - 9:39 pm
DTW
-
SFO
30h 37m
1 stop
Multiple Airlines Logo
10:58 pm - 9:13 pm
SFO
-
DTW
19h 15m
1 stop
$294Multiple Airlines
Thu, Feb 12 - Sun, Feb 15
Alaska Airlines Logo
5:10 pm - 10:28 pm
DTW
-
SFO
8h 18m
1 stop
Alaska Airlines Logo
9:20 am - 5:49 am
SFO
-
DTW
17h 29m
2 stops
$295Alaska Airlines
Wed, Apr 22 - Tue, Apr 28
Frontier Logo
6:00 am - 5:46 pm
DTW
-
SFO
14h 46m
1 stop
Frontier Logo
11:16 pm - 10:17 am
SFO
-
DTW
8h 01m
1 stop
$296Frontier
Sun, May 10 - Thu, May 14
Multiple Airlines Logo
6:00 am - 11:00 am
DTW
-
SFO
32h 00m
2 stops
Multiple Airlines Logo
6:15 am - 11:55 pm
SFO
-
DTW
14h 40m
1 stop
$297Multiple Airlines
Tue, Feb 24 - Sat, Feb 28
Frontier Logo
8:30 am - 10:01 pm
DTW
-
SFO
16h 31m
1 stop
Frontier Logo
11:00 pm - 9:46 am
SFO
-
DTW
31h 46m
2 stops
$298Frontier
Tue, Feb 10 - Sat, Feb 14

United Airlines flights from Detroit to San Francisco

Our best United Airlines deals on Detroit to San Francisco flight tickets
United Airlines
May 29
DTW6:24 amDetroit Metropolitan Wayne County
5h 06m
SFO8:30 amSan Francisco
Jun 2
SFO9:25 pmSan Francisco
4h 50m
DTW5:15 amDetroit Metropolitan Wayne County
$289
United Airlines
Feb 19
DTW6:00 amDetroit Metropolitan Wayne County
7h 50m
1 stop
SFO10:50 amSan Francisco
Feb 24
SFO1:20 pmSan Francisco
4h 39m
DTW8:59 pmDetroit Metropolitan Wayne County
$299
United Airlines
Feb 19
DTW6:00 amDetroit Metropolitan Wayne County
7h 50m
1 stop
SFO10:50 amSan Francisco
Feb 27
SFO11:20 pmSan Francisco
7h 41m
1 stop
DTW10:01 amDetroit Metropolitan Wayne County
$309

Frontier flights from Detroit to San Francisco

Our best Frontier deals on Detroit to San Francisco flight tickets
Frontier
Apr 19
DTW10:27 pmDetroit Metropolitan Wayne County
13h 41m
1 stop
SFO9:08 amSan Francisco
May 7
SFO6:00 amSan Francisco
12h 41m
1 stop
DTW9:41 pmDetroit Metropolitan Wayne County
$290
Frontier
Feb 28
DTW5:21 pmDetroit Metropolitan Wayne County
10h 07m
1 stop
SFO12:28 amSan Francisco
Mar 17
SFO9:04 pmSan Francisco
10h 55m
1 stop
DTW10:59 amDetroit Metropolitan Wayne County
$291
Frontier
Feb 10
DTW8:30 amDetroit Metropolitan Wayne County
16h 31m
1 stop
SFO10:01 pmSan Francisco
Feb 15
SFO6:15 amSan Francisco
14h 40m
1 stop
DTW11:55 pmDetroit Metropolitan Wayne County
$295

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Detroit to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 5/29

6:24 am-8:30 am

Nonstop5h 06m

San Francisco

Tue 6/2

9:25 pm-5:15 am

Nonstop4h 50m

$289

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sun 4/19

10:27 pm-9:08 am

1 stop13h 41m

San Francisco

Thu 5/7

6:00 am-9:41 pm

1 stop12h 41m

$290

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 2/28

5:21 pm-12:28 am

1 stop10h 07m

San Francisco

Tue 3/17

9:04 pm-10:59 am

1 stop10h 55m

$291

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 2/27

6:00 am-12:28 am

1 stop21h 28m

San Francisco

Sat 3/7

10:38 pm-2:57 pm

1 stop13h 19m

$292

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 4/21

4:55 pm-9:58 am

2 stops20h 03m

San Francisco

Tue 5/5

10:38 pm-11:31 am

1 stop9h 53m

$293

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 2/12

6:02 pm-9:39 pm

1 stop30h 37m

San Francisco

Sun 2/15

10:58 pm-9:13 pm

1 stop19h 15m

$294

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 4/22

5:10 pm-10:28 pm

1 stop8h 18m

San Francisco

Tue 4/28

9:20 am-5:49 am

2 stops17h 29m

$295

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sun 5/10

6:00 am-5:46 pm

1 stop14h 46m

San Francisco

Thu 5/14

11:16 pm-10:17 am

1 stop8h 01m

$296

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 2/24

6:00 am-11:00 am

2 stops32h 00m

San Francisco

Sat 2/28

6:15 am-11:55 pm

1 stop14h 40m

$297

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 2/10

8:30 am-10:01 pm

1 stop16h 31m

San Francisco

Sat 2/14

11:00 pm-9:46 am

2 stops31h 46m

$298

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Detroit to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of July, then flying in June is also cheap. Prices for this month can be found on momondo for an average of $389.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Detroit to San Francisco is on a Thursday when prices can be found for as low as $495. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $672.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Detroit to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $517. Flights in the afternoon are often more expensive with an average ticket price of $565.

What is the cheapest Detroit to San Francisco flight route?

Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $455 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit for as low as $338 on momondo.

What cabin class options are available on Detroit to San Francisco flights?

There are 4 cabin classes available to choose from on Detroit to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Detroit to San Francisco flight prices changed over time?

As of January 2026, prices for Detroit to San Francisco flights are approximately 64% more expensive when compared to flights at the same time last year.

When to book flights from Detroit to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to San Francisco (DTT to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to San Francisco

Best Price Found

$218

Fastest flight time

5h 04m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Detroit in the past 72 hours is $218. The best round-trip flight deal from Detroit to San Francisco found on momondo in the last 72 hours is $388.
The fastest flight from Detroit to San Francisco takes 5h 04m
Direct flights go from Detroit to San Francisco every day.
There is 1 airport in San Francisco. From Detroit there are direct flights to San Francisco (SFO).
Search flight deals

  • How far is Detroit to San Francisco by plane?

    A flight from Detroit to San Francisco will travel around 2084.6 mi. Typically, this will take 5h 04m by plane in normal conditions.

  • When did momondo last update prices for flights from Detroit to San Francisco Airport?

    Prices for flights from Detroit to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to San Francisco Airport?

  • How old do you have to be to fly from Detroit to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Detroit to San Francisco?

  • What is the most popular airline from Detroit to San Francisco?

Best airlines flying from Detroit to San Francisco

Compare and see reviews for airlines that fly from Detroit to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Sun Country AirPriceFrom $126Free CancellationRating
6.9
343 reviews
Search Sun Country Air flights
FrontierPriceFrom $134Free CancellationRating
5.7
3,056 reviews
Search Frontier flights
JetBluePriceFrom $259Free CancellationRating
7.2
2,891 reviews
Search JetBlue flights
SouthwestPriceFrom $288Free CancellationRating
8.0
4,267 reviews
Search Southwest flights
United AirlinesPriceFrom $289Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
8,127 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,206 reviews
Search American Airlines flights

  • Delta Flights From Detroit to San Francisco

    The lowest priced Delta flight from Detroit to San Francisco from the last 72 hours was $289. Generally, Delta has 15 flights on this route every week with an average price of $521. Delta is rated 7.9/10 by our users.

  • United Airlines Flights From Detroit to San Francisco

    United Airlines is also a popular choice for this route. United Airlines flight deals for Detroit to San Francisco start from as low as $289 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $404. United Airlines operates 7 flights to San Francisco from Detroit in an average week. Users have rated it 7.4/10 across 9,215 reviews.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Santa Clara
Berkeley
Walnut Creek
Fremont
Daly City
Half Moon Bay
Salinas
Vallejo
Livermore
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Detroit to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to San Francisco?

momondo helps you find the best flight between Detroit and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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