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Cheap flights from Myrtle Beach to Los Angeles from $188

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Los Angeles departing on 7/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:45 pm - 8:43 pm
MYR
-
SNA
8h 58m
1 stop
American Airlines Logo
7:45 am - 7:21 pm
SNA
-
MYR
8h 36m
1 stop
$363American Airlines
Wed, Nov 18 - Wed, Dec 2
United Airlines Logo
11:30 am - 9:01 pm
MYR
-
SNA
12h 31m
2 stops
United Airlines Logo
6:28 pm - 10:37 am
SNA
-
MYR
13h 09m
2 stops
$374United Airlines
Wed, Nov 18 - Wed, Dec 2
American Airlines Logo
5:03 am - 1:51 pm
MYR
-
SNA
11h 48m
2 stops
American Airlines Logo
7:45 am - 7:21 pm
SNA
-
MYR
8h 36m
1 stop
$417American Airlines
Wed, Nov 18 - Wed, Dec 2
American Airlines Logo
12:14 pm - 6:10 pm
MYR
-
SNA
8h 56m
1 stop
American Airlines Logo
3:21 pm - 11:34 am
SNA
-
MYR
17h 13m
1 stop
$419American Airlines
Wed, Aug 12 - Tue, Aug 18
Southwest Logo
11:00 am - 5:30 pm
MYR
-
SNA
9h 30m
2 stops
Southwest Logo
6:45 am - 7:20 pm
SNA
-
MYR
9h 35m
2 stops
$425Southwest
Wed, Aug 12 - Tue, Aug 18
Delta Logo
2:15 pm - 6:38 pm
MYR
-
SNA
7h 23m
1 stop
Delta Logo
2:00 pm - 11:35 pm
SNA
-
MYR
6h 35m
1 stop
$440Delta
Fri, Nov 13 - Mon, Nov 16
Southwest Logo
2:00 pm - 9:10 pm
MYR
-
SNA
10h 10m
2 stops
Southwest Logo
8:40 pm - 10:05 am
SNA
-
MYR
10h 25m
2 stops
$450Southwest
Fri, Aug 28 - Mon, Aug 31
American Airlines Logo
5:21 pm - 10:45 pm
MYR
-
SNA
8h 24m
1 stop
American Airlines Logo
6:45 am - 4:41 pm
SNA
-
MYR
6h 56m
1 stop
$467American Airlines
Fri, Nov 6 - Mon, Nov 23
American Airlines Logo
5:03 am - 1:51 pm
MYR
-
SNA
11h 48m
2 stops
American Airlines Logo
8:30 am - 10:05 pm
SNA
-
MYR
10h 35m
2 stops
$470American Airlines
Wed, Nov 18 - Wed, Dec 2
United Airlines Logo
10:00 am - 5:18 pm
MYR
-
SNA
10h 18m
1 stop
United Airlines Logo
7:27 pm - 2:19 pm
SNA
-
MYR
15h 52m
2 stops
$480United Airlines
Thu, Jul 9 - Wed, Jul 15

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Southwest flights from Myrtle Beach to Santa Ana, California

Our best Southwest deals on Myrtle Beach to Santa Ana, California flight tickets
Southwest
Aug 12
MYR11:00 amMyrtle Beach Intl
9h 30m
2 stops
SNA5:30 pmSanta Ana J. Wayne/Orange Cnty
Aug 18
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
9h 35m
2 stops
MYR7:20 pmMyrtle Beach Intl
$425
Southwest
Aug 28
MYR2:00 pmMyrtle Beach Intl
10h 10m
2 stops
SNA9:10 pmSanta Ana J. Wayne/Orange Cnty
Aug 31
SNA8:40 pmSanta Ana J. Wayne/Orange Cnty
10h 25m
2 stops
MYR10:05 amMyrtle Beach Intl
$450
Southwest
Jul 9
MYR5:15 amMyrtle Beach Intl
9h 10m
2 stops
SNA11:25 amSanta Ana J. Wayne/Orange Cnty
Jul 15
SNA8:35 amSanta Ana J. Wayne/Orange Cnty
9h 00m
2 stops
MYR8:35 pmMyrtle Beach Intl
$573

Delta flights from Myrtle Beach to Santa Ana, California

Our best Delta deals on Myrtle Beach to Santa Ana, California flight tickets
Delta
Nov 13
MYR2:15 pmMyrtle Beach Intl
7h 23m
1 stop
SNA6:38 pmSanta Ana J. Wayne/Orange Cnty
Nov 16
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 35m
1 stop
MYR11:35 pmMyrtle Beach Intl
$440
Delta
Aug 29
MYR6:00 amMyrtle Beach Intl
9h 46m
1 stop
SNA12:46 pmSanta Ana J. Wayne/Orange Cnty
Aug 31
SNA2:15 pmSanta Ana J. Wayne/Orange Cnty
17h 23m
2 stops
MYR10:38 amMyrtle Beach Intl
$506
Delta
Aug 29
MYR6:00 amMyrtle Beach Intl
9h 46m
1 stop
SNA12:46 pmSanta Ana J. Wayne/Orange Cnty
Aug 31
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
17h 47m
1 stop
MYR10:47 amMyrtle Beach Intl
$565

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 11/18

2:45 pm-8:43 pm

1 stop8h 58m

Santa Ana J. Wayne/Orange Cnty

Wed 12/2

7:45 am-7:21 pm

1 stop8h 36m

$363

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 11/18

11:30 am-9:01 pm

2 stops12h 31m

Santa Ana J. Wayne/Orange Cnty

Wed 12/2

6:28 pm-10:37 am

2 stops13h 09m

$374

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 11/18

5:03 am-1:51 pm

2 stops11h 48m

Santa Ana J. Wayne/Orange Cnty

Wed 12/2

7:45 am-7:21 pm

1 stop8h 36m

$417

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 8/12

12:14 pm-6:10 pm

1 stop8h 56m

Santa Ana J. Wayne/Orange Cnty

Tue 8/18

3:21 pm-11:34 am

1 stop17h 13m

$419

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 8/12

11:00 am-5:30 pm

2 stops9h 30m

Santa Ana J. Wayne/Orange Cnty

Tue 8/18

6:45 am-7:20 pm

2 stops9h 35m

$425
Quickest round-trip

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 11/13

2:15 pm-6:38 pm

1 stop7h 23m

Santa Ana J. Wayne/Orange Cnty

Mon 11/16

2:00 pm-11:35 pm

1 stop6h 35m

$440

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 8/28

2:00 pm-9:10 pm

2 stops10h 10m

Santa Ana J. Wayne/Orange Cnty

Mon 8/31

8:40 pm-10:05 am

2 stops10h 25m

$450

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 11/6

5:21 pm-10:45 pm

1 stop8h 24m

Santa Ana J. Wayne/Orange Cnty

Mon 11/23

6:45 am-4:41 pm

1 stop6h 56m

$467

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 11/18

5:03 am-1:51 pm

2 stops11h 48m

Santa Ana J. Wayne/Orange Cnty

Wed 12/2

8:30 am-10:05 pm

2 stops10h 35m

$470

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Thu 7/9

10:00 am-5:18 pm

1 stop10h 18m

Santa Ana J. Wayne/Orange Cnty

Wed 7/15

7:27 pm-2:19 pm

2 stops15h 52m

$480

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Myrtle Beach to Santa Ana, California flights?

You could potentially save up to 21% on your flight if you consider stops on a Myrtle Beach to Santa Ana, California flight.

When to book flights from Myrtle Beach to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santa Ana, California (MYR to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santa Ana, California

Fastest flight time

7h 23m

Direct flights

None
The fastest flight from Myrtle Beach to Santa Ana, California takes 7h 23m
There are no direct flights from Myrtle Beach to Santa Ana, California. There are no popular flight routes from Myrtle Beach to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Santa Ana, California

  • How far is Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty by plane?

    Myrtle Beach Intl and Santa Ana J. Wayne/Orange Cnty are 2225.0 mi apart from one another. Typically, this will take 7h 23m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Santa Ana, California?

Best airlines flying from Myrtle Beach to Santa Ana, California

Compare and see reviews for airlines that fly from Myrtle Beach to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $306Free CancellationRating
7.1
11,746 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
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Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Myrtle Beach to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Myrtle Beach to Santa Ana with flexible booking policies on momondo?

Flights from Myrtle Beach to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Santa Ana?

Once all potential Myrtle Beach to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Santa Ana right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Ana from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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