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Cheap flights from Myrtle Beach to Los Angeles from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Los Angeles departing on 7/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:21 pm - 10:14 pm
MYR
-
SNA
9h 53m
1 stop
United Airlines Logo
9:14 pm - 8:58 am
SNA
-
MYR
8h 44m
1 stop
$404United Airlines
Tue, Sep 15 - Sat, Sep 19
United Airlines Logo
10:00 am - 5:18 pm
MYR
-
SNA
10h 18m
1 stop
United Airlines Logo
6:26 pm - 9:04 am
SNA
-
MYR
11h 38m
2 stops
$408United Airlines
Tue, Jun 2 - Tue, Jun 9
United Airlines Logo
3:21 pm - 10:14 pm
MYR
-
SNA
9h 53m
1 stop
United Airlines Logo
6:30 pm - 8:58 am
SNA
-
MYR
11h 28m
2 stops
$409United Airlines
Tue, Sep 15 - Sat, Sep 19
United Airlines Logo
11:25 am - 8:51 pm
MYR
-
SNA
12h 26m
2 stops
United Airlines Logo
6:30 pm - 8:58 am
SNA
-
MYR
11h 28m
2 stops
$414United Airlines
Tue, Sep 15 - Sat, Sep 19
Delta Logo
11:32 am - 9:54 pm
MYR
-
SNA
13h 22m
2 stops
Delta Logo
8:00 am - 11:59 pm
SNA
-
MYR
12h 59m
2 stops
$423Delta
Tue, Jun 2 - Tue, Jun 9
Delta Logo
6:00 am - 12:40 pm
MYR
-
SNA
9h 40m
1 stop
Delta Logo
2:00 pm - 11:58 pm
SNA
-
MYR
6h 58m
1 stop
$425Delta
Sun, May 24 - Tue, Jun 2
United Airlines Logo
10:00 am - 6:59 pm
MYR
-
SNA
11h 59m
2 stops
United Airlines Logo
6:26 pm - 9:04 am
SNA
-
MYR
11h 38m
2 stops
$426United Airlines
Tue, Jun 2 - Tue, Jun 9
Delta Logo
1:30 pm - 6:33 pm
MYR
-
SNA
8h 03m
1 stop
Delta Logo
2:00 pm - 11:58 pm
SNA
-
MYR
6h 58m
1 stop
$435Delta
Sun, May 24 - Tue, Jun 2
Delta Logo
1:30 pm - 6:33 pm
MYR
-
SNA
8h 03m
1 stop
Delta Logo
2:00 pm - 11:58 pm
SNA
-
MYR
6h 58m
1 stop
$440Delta
Sun, May 24 - Tue, Jun 2
Delta Logo
6:00 am - 11:55 am
MYR
-
SNA
8h 55m
2 stops
Delta Logo
2:00 pm - 11:58 pm
SNA
-
MYR
6h 58m
1 stop
$445Delta
Sun, May 24 - Tue, Jun 2

United Airlines flights from Myrtle Beach to Santa Ana, California

Our best United Airlines deals on Myrtle Beach to Santa Ana, California flight tickets
United Airlines
Sep 15
MYR3:21 pmMyrtle Beach Intl
9h 53m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
Sep 19
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
8h 44m
1 stop
MYR8:58 amMyrtle Beach Intl
$404
United Airlines
Jun 2
MYR10:00 amMyrtle Beach Intl
10h 18m
1 stop
SNA5:18 pmSanta Ana J. Wayne/Orange Cnty
Jun 9
SNA6:26 pmSanta Ana J. Wayne/Orange Cnty
11h 38m
2 stops
MYR9:04 amMyrtle Beach Intl
$408
United Airlines
Sep 15
MYR3:21 pmMyrtle Beach Intl
9h 53m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
Sep 19
SNA6:30 pmSanta Ana J. Wayne/Orange Cnty
11h 28m
2 stops
MYR8:58 amMyrtle Beach Intl
$409

Delta flights from Myrtle Beach to Santa Ana, California

Our best Delta deals on Myrtle Beach to Santa Ana, California flight tickets
Delta
Jun 2
MYR11:32 amMyrtle Beach Intl
13h 22m
2 stops
SNA9:54 pmSanta Ana J. Wayne/Orange Cnty
Jun 9
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
12h 59m
2 stops
MYR11:59 pmMyrtle Beach Intl
$423
Delta
May 24
MYR6:00 amMyrtle Beach Intl
9h 40m
1 stop
SNA12:40 pmSanta Ana J. Wayne/Orange Cnty
Jun 2
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 58m
1 stop
MYR11:58 pmMyrtle Beach Intl
$425
Delta
May 24
MYR1:30 pmMyrtle Beach Intl
8h 03m
1 stop
SNA6:33 pmSanta Ana J. Wayne/Orange Cnty
Jun 2
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 58m
1 stop
MYR11:58 pmMyrtle Beach Intl
$435

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/15

3:21 pm-10:14 pm

1 stop9h 53m

Santa Ana J. Wayne/Orange Cnty

Sat 9/19

9:14 pm-8:58 am

1 stop8h 44m

$404

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 6/2

10:00 am-5:18 pm

1 stop10h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 6/9

6:26 pm-9:04 am

2 stops11h 38m

$408

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/15

3:21 pm-10:14 pm

1 stop9h 53m

Santa Ana J. Wayne/Orange Cnty

Sat 9/19

6:30 pm-8:58 am

2 stops11h 28m

$409

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/15

11:25 am-8:51 pm

2 stops12h 26m

Santa Ana J. Wayne/Orange Cnty

Sat 9/19

6:30 pm-8:58 am

2 stops11h 28m

$414

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 6/2

11:32 am-9:54 pm

2 stops13h 22m

Santa Ana J. Wayne/Orange Cnty

Tue 6/9

8:00 am-11:59 pm

2 stops12h 59m

$423

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 5/24

6:00 am-12:40 pm

1 stop9h 40m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

2:00 pm-11:58 pm

1 stop6h 58m

$425

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 6/2

10:00 am-6:59 pm

2 stops11h 59m

Santa Ana J. Wayne/Orange Cnty

Tue 6/9

6:26 pm-9:04 am

2 stops11h 38m

$426
Quickest round-trip

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 5/24

1:30 pm-6:33 pm

1 stop8h 03m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

2:00 pm-11:58 pm

1 stop6h 58m

$435

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 5/24

1:30 pm-6:33 pm

1 stop8h 03m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

2:00 pm-11:58 pm

1 stop6h 58m

$440

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 5/24

6:00 am-11:55 am

2 stops8h 55m

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

2:00 pm-11:58 pm

1 stop6h 58m

$445

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Myrtle Beach to Santa Ana, California flights?

You could potentially save up to 4% on your flight if you consider stops on a Myrtle Beach to Santa Ana, California flight.

When to book flights from Myrtle Beach to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santa Ana, California (MYR to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santa Ana, California

Fastest flight time

9h 53m

Direct flights

None
The fastest flight from Myrtle Beach to Santa Ana, California takes 9h 53m
There are no direct flights from Myrtle Beach to Santa Ana, California. There are no popular flight routes from Myrtle Beach to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Santa Ana, California

  • How far is Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty by plane?

    Myrtle Beach Intl and Santa Ana J. Wayne/Orange Cnty are 2225.0 mi apart from one another. Typically, this will take 9h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Santa Ana, California?

Best airlines flying from Myrtle Beach to Santa Ana, California

Compare and see reviews for airlines that fly from Myrtle Beach to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $306Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
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Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Myrtle Beach to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Myrtle Beach to Santa Ana with flexible booking policies on momondo?

Flights from Myrtle Beach to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Santa Ana?

Once all potential Myrtle Beach to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Santa Ana right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Ana from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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