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Cheap flights from Myrtle Beach to Los Angeles from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Los Angeles departing on 9/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Myrtle Beach to Los Angeles (MYR-SNA)

Cheap round-trip flights

American Airlines Logo
12:40 pm - 6:28 pmMYR-SNA
8h 48m2 stops
American Airlines Logo
11:42 am - 10:54 pmSNA-MYR
8h 12m1 stop
$427American Airlines
Find Deal
Sat, Sep 6 - Sun, Sep 14
United Airlines Logo
11:29 am - 8:28 pmMYR-SNA
11h 59m2 stops
United Airlines Logo
9:14 pm - 10:36 amSNA-MYR
10h 22m1 stop
$431United Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
Delta Logo
12:30 pm - 8:25 pmMYR-SNA
10h 55m2 stops
Delta Logo
9:20 pm - 10:39 amSNA-MYR
10h 19m2 stops
$432Delta
Find Deal
Sat, Sep 6 - Sun, Sep 14
United Airlines Logo
4:45 pm - 10:30 pmMYR-SNA
8h 45m1 stop
United Airlines Logo
9:14 pm - 10:36 amSNA-MYR
10h 22m1 stop
$446United Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
American Airlines Logo
7:00 am - 11:57 amMYR-SNA
7h 57m1 stop
American Airlines Logo
12:53 pm - 10:54 pmSNA-MYR
7h 01m1 stop
$460American Airlines
Find Deal
Sat, Sep 6 - Sun, Sep 14
American Airlines Logo
6:15 am - 3:48 pmMYR-SNA
12h 33m2 stops
American Airlines Logo
11:42 am - 10:54 pmSNA-MYR
8h 12m1 stop
$464American Airlines
Find Deal
Sat, Sep 6 - Sun, Sep 14
American Airlines Logo
8:06 am - 3:48 pmMYR-SNA
10h 42m2 stops
American Airlines Logo
7:12 pm - 9:33 amSNA-MYR
11h 21m2 stops
$470American Airlines
Find Deal
Sat, Sep 6 - Sun, Sep 14
Spirit Airlines Logo
9:59 am - 8:59 pmMYR-SNA
14h 00m2 stops
Spirit Airlines Logo
5:46 pm - 10:41 amSNA-MYR
13h 55m2 stops
$621Spirit Airlines
Find Deal
Sat, Dec 13 - Mon, Dec 22
United Airlines Logo
11:29 am - 8:28 pmMYR-SNA
11h 59m2 stops
United Airlines Logo
4:15 pm - 2:42 pmSNA-MYR
19h 27m2 stops
$636United Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
United Airlines Logo
4:45 pm - 12:44 pmMYR-SNA
22h 59m2 stops
United Airlines Logo
9:14 pm - 10:36 amSNA-MYR
10h 22m1 stop
$721United Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6

American Airlines flights from Myrtle Beach to Santa Ana

Our best American Airlines deals on Myrtle Beach to Santa Ana flight tickets
American Airlines
Sep 6
MYR12:40 pmMyrtle Beach Intl
8h 48m
2 stops
SNA6:28 pmSanta Ana J. Wayne/Orange Cnty
Sep 14
SNA11:42 amSanta Ana J. Wayne/Orange Cnty
8h 12m
1 stop
MYR10:54 pmMyrtle Beach Intl
$427
Find similar
American Airlines
Sep 6
MYR7:00 amMyrtle Beach Intl
7h 57m
1 stop
SNA11:57 amSanta Ana J. Wayne/Orange Cnty
Sep 14
SNA12:53 pmSanta Ana J. Wayne/Orange Cnty
7h 01m
1 stop
MYR10:54 pmMyrtle Beach Intl
$460
Find similar
American Airlines
Sep 6
MYR6:15 amMyrtle Beach Intl
12h 33m
2 stops
SNA3:48 pmSanta Ana J. Wayne/Orange Cnty
Sep 14
SNA11:42 amSanta Ana J. Wayne/Orange Cnty
8h 12m
1 stop
MYR10:54 pmMyrtle Beach Intl
$464
Find similar

United Airlines flights from Myrtle Beach to Santa Ana

Our best United Airlines deals on Myrtle Beach to Santa Ana flight tickets
United Airlines
Sep 9
MYR11:29 amMyrtle Beach Intl
11h 59m
2 stops
SNA8:28 pmSanta Ana J. Wayne/Orange Cnty
Sep 13
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
10h 22m
1 stop
MYR10:36 amMyrtle Beach Intl
$431
Find similar
United Airlines
Sep 9
MYR4:45 pmMyrtle Beach Intl
8h 45m
1 stop
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
Sep 13
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
10h 22m
1 stop
MYR10:36 amMyrtle Beach Intl
$446
Find similar
United Airlines
Sep 9
MYR11:29 amMyrtle Beach Intl
11h 59m
2 stops
SNA8:28 pmSanta Ana J. Wayne/Orange Cnty
Sep 13
SNA4:15 pmSanta Ana J. Wayne/Orange Cnty
19h 27m
2 stops
MYR2:42 pmMyrtle Beach Intl
$636
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 9/6

12:40 pm-6:28 pm

2 stops8h 48m

Santa Ana J. Wayne/Orange Cnty

Sun 9/14

11:42 am-10:54 pm

1 stop8h 12m

$427

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/9

11:29 am-8:28 pm

2 stops11h 59m

Santa Ana J. Wayne/Orange Cnty

Sat 9/13

9:14 pm-10:36 am

1 stop10h 22m

$431

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 9/6

12:30 pm-8:25 pm

2 stops10h 55m

Santa Ana J. Wayne/Orange Cnty

Sun 9/14

9:20 pm-10:39 am

2 stops10h 19m

$432

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/9

4:45 pm-10:30 pm

1 stop8h 45m

Santa Ana J. Wayne/Orange Cnty

Sat 9/13

9:14 pm-10:36 am

1 stop10h 22m

$446

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 9/6

7:00 am-11:57 am

1 stop7h 57m

Santa Ana J. Wayne/Orange Cnty

Sun 9/14

12:53 pm-10:54 pm

1 stop7h 01m

$460

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 9/6

6:15 am-3:48 pm

2 stops12h 33m

Santa Ana J. Wayne/Orange Cnty

Sun 9/14

11:42 am-10:54 pm

1 stop8h 12m

$464

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 9/6

8:06 am-3:48 pm

2 stops10h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 9/14

7:12 pm-9:33 am

2 stops11h 21m

$470

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 12/13

9:59 am-8:59 pm

2 stops14h 00m

Santa Ana J. Wayne/Orange Cnty

Mon 12/22

5:46 pm-10:41 am

2 stops13h 55m

$621

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/9

11:29 am-8:28 pm

2 stops11h 59m

Santa Ana J. Wayne/Orange Cnty

Sat 9/13

4:15 pm-2:42 pm

2 stops19h 27m

$636

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 9/2

4:45 pm-12:44 pm

2 stops22h 59m

Santa Ana J. Wayne/Orange Cnty

Sat 9/6

9:14 pm-10:36 am

1 stop10h 22m

$721

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Myrtle Beach is on a Saturday. momondo users have found tickets for Saturday departures for as low as $403. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Myrtle Beach because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $611.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Myrtle Beach to Santa Ana flights are usually those with departure times in the morning. Our users have found flights to Santa Ana in the morning for as low as $463. Try not to purchase tickets at noon because they tend to be around $564. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Myrtle Beach to Santa Ana flights?

You could potentially save up to 50% on your flight if you consider stops on a Myrtle Beach to Santa Ana flight.

When to book flights from Myrtle Beach to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Santa Ana (MYR to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Santa Ana

Best Price Found

$136

Fastest flight time

7h 57m

Direct flights

None

Airports in Santa Ana

1 airport
The best one-way flight to Santa Ana from Myrtle Beach in the past 72 hours is $136. The best round-trip flight deal from Myrtle Beach to Santa Ana found on momondo in the last 72 hours is $427.
The fastest flight from Myrtle Beach to Santa Ana takes 7h 57m
There are no direct flights from Myrtle Beach to Santa Ana. Popular non-direct route for this connection is Myrtle Beach Intl Airport - Santa Ana J. Wayne/Orange Cnty Airport.
There is 1 airport near Santa Ana: Santa Ana J. Wayne/Orange Cnty (SNA)
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  • How far is Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty by plane?

    Myrtle Beach Intl and Santa Ana J. Wayne/Orange Cnty are 2225.0 mi apart from one another. Typically, this will take 7h 57m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to Santa Ana?

Best airlines flying from Myrtle Beach to Santa Ana

Compare and see reviews for airlines that fly from Myrtle Beach to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $296Free CancellationRating
8.0
7,986 reviews
Search Delta flights
American AirlinesPriceFrom $319Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

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Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Myrtle Beach to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Myrtle Beach to Santa Ana with flexible booking policies on momondo?

Flights from Myrtle Beach to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Santa Ana?

Once all potential Myrtle Beach to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Santa Ana right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Ana from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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