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Cheap flights from Myrtle Beach to San Antonio from $204

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to San Antonio departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
11:46 am - 3:11 pmMYR-SAT
28h 25m1 stop
Spirit Airlines Logo
4:16 pm - 10:41 amSAT-MYR
17h 25m1 stop
$288Spirit Airlines
Find Deal
Tue, Dec 9 - Fri, Dec 12
Spirit Airlines Logo
9:05 pm - 6:30 pmMYR-SAT
22h 25m1 stop
Spirit Airlines Logo
4:55 pm - 9:27 amSAT-MYR
15h 32m1 stop
$309Spirit Airlines
Find Deal
Thu, Oct 16 - Mon, Oct 20
Multiple Airlines Logo
9:05 pm - 6:30 pmMYR-SAT
22h 25m1 stop
Multiple Airlines Logo
3:59 pm - 2:09 pmSAT-MYR
21h 10m2 stops
$314Multiple Airlines
Find Deal
Thu, Oct 16 - Wed, Oct 22
Southwest Logo
8:15 pm - 12:15 amMYR-SAT
5h 00m1 stop
Southwest Logo
6:50 am - 2:15 pmSAT-MYR
6h 25m1 stop
$315Southwest
Find Deal
Fri, Nov 7 - Tue, Nov 11
Multiple Airlines Logo
2:59 pm - 6:30 pmMYR-SAT
28h 31m2 stops
Multiple Airlines Logo
4:55 pm - 9:27 amSAT-MYR
15h 32m1 stop
$318Multiple Airlines
Find Deal
Thu, Oct 16 - Mon, Oct 20
American Airlines Logo
4:03 pm - 10:35 pmMYR-SAT
7h 32m1 stop
American Airlines Logo
5:00 am - 2:44 pmSAT-MYR
8h 44m2 stops
$320American Airlines
Find Deal
Tue, Dec 9 - Fri, Dec 12
Southwest Logo
12:40 pm - 8:10 pmMYR-SAT
8h 30m2 stops
Southwest Logo
6:20 am - 2:15 pmSAT-MYR
6h 55m2 stops
$325Southwest
Find Deal
Fri, Nov 7 - Tue, Nov 11
American Airlines Logo
5:13 pm - 11:51 pmMYR-SAT
7h 38m1 stop
American Airlines Logo
5:48 pm - 11:55 pmSAT-MYR
5h 07m1 stop
$333American Airlines
Find Deal
Thu, Dec 18 - Mon, Dec 22
Delta Logo
6:00 am - 11:30 amMYR-SAT
6h 30m1 stop
Delta Logo
4:25 pm - 11:35 pmSAT-MYR
6h 10m1 stop
$407Delta
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Tue, Mar 10 - Wed, Mar 11
Delta Logo
6:45 pm - 12:14 amMYR-SAT
6h 29m1 stop
Delta Logo
4:25 pm - 11:35 pmSAT-MYR
6h 10m1 stop
$437Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11

Southwest flights from Myrtle Beach to San Antonio

Our best Southwest deals on Myrtle Beach to San Antonio flight tickets
Southwest
Nov 7
MYR8:15 pmMyrtle Beach Intl
5h 00m
1 stop
SAT12:15 amSan Antonio
Nov 11
SAT6:50 amSan Antonio
6h 25m
1 stop
MYR2:15 pmMyrtle Beach Intl
$315
Find similar
Southwest
Nov 7
MYR12:40 pmMyrtle Beach Intl
8h 30m
2 stops
SAT8:10 pmSan Antonio
Nov 11
SAT6:20 amSan Antonio
6h 55m
2 stops
MYR2:15 pmMyrtle Beach Intl
$325
Find similar
Southwest
Dec 9
MYR2:55 pmMyrtle Beach Intl
8h 00m
2 stops
SAT9:55 pmSan Antonio
Dec 12
SAT12:10 pmSan Antonio
6h 30m
2 stops
MYR7:40 pmMyrtle Beach Intl
$364
Find similar

Delta flights from Myrtle Beach to San Antonio

Our best Delta deals on Myrtle Beach to San Antonio flight tickets
Delta
Mar 10
MYR6:00 amMyrtle Beach Intl
6h 30m
1 stop
SAT11:30 amSan Antonio
Mar 11
SAT4:25 pmSan Antonio
6h 10m
1 stop
MYR11:35 pmMyrtle Beach Intl
$407
Find similar
Delta
Mar 10
MYR6:45 pmMyrtle Beach Intl
6h 29m
1 stop
SAT12:14 amSan Antonio
Mar 11
SAT4:25 pmSan Antonio
6h 10m
1 stop
MYR11:35 pmMyrtle Beach Intl
$437
Find similar
Delta
Oct 14
MYR6:58 pmMyrtle Beach Intl
6h 22m
1 stop
SAT12:20 amSan Antonio
Oct 19
SAT6:21 pmSan Antonio
4h 38m
1 stop
MYR11:59 pmMyrtle Beach Intl
$467
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 12/9

11:46 am-3:11 pm

1 stop28h 25m

San Antonio

Fri 12/12

4:16 pm-10:41 am

1 stop17h 25m

$288

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Thu 10/16

9:05 pm-6:30 pm

1 stop22h 25m

San Antonio

Mon 10/20

4:55 pm-9:27 am

1 stop15h 32m

$309

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Thu 10/16

9:05 pm-6:30 pm

1 stop22h 25m

San Antonio

Wed 10/22

3:59 pm-2:09 pm

2 stops21h 10m

$314

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Fri 11/7

8:15 pm-12:15 am

1 stop5h 00m

San Antonio

Tue 11/11

6:50 am-2:15 pm

1 stop6h 25m

$315

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Thu 10/16

2:59 pm-6:30 pm

2 stops28h 31m

San Antonio

Mon 10/20

4:55 pm-9:27 am

1 stop15h 32m

$318

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 12/9

4:03 pm-10:35 pm

1 stop7h 32m

San Antonio

Fri 12/12

5:00 am-2:44 pm

2 stops8h 44m

$320

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Fri 11/7

12:40 pm-8:10 pm

2 stops8h 30m

San Antonio

Tue 11/11

6:20 am-2:15 pm

2 stops6h 55m

$325

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Thu 12/18

5:13 pm-11:51 pm

1 stop7h 38m

San Antonio

Mon 12/22

5:48 pm-11:55 pm

1 stop5h 07m

$333

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 3/10

6:00 am-11:30 am

1 stop6h 30m

San Antonio

Wed 3/11

4:25 pm-11:35 pm

1 stop6h 10m

$407

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 3/10

6:45 pm-12:14 am

1 stop6h 29m

San Antonio

Wed 3/11

4:25 pm-11:35 pm

1 stop6h 10m

$437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to San Antonio from

How to get the cheapest flight ticket from Myrtle Beach to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Antonio?

If you aren’t able to travel during the month of May, then book flights to San Antonio from Myrtle Beach during August instead. Flights to San Antonio in August, while not as cheap as those in May, still average around $291.

What is the cheapest day to depart on your flight to San Antonio?

The cheapest day to depart on your flight to San Antonio is on a Wednesday when prices can be found for as low as $351. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to San Antonio on Friday is $457.

What is the cheapest time of day to depart on your flight to San Antonio?

According to our data, the cheapest time of day to fly to San Antonio is at noon. momondo users have found flights departing from Myrtle Beach to San Antonio at noon for as low as $374. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to San Antonio are more costly in the evening, with an average ticket price of $436. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

How have Myrtle Beach to San Antonio flight prices changed over time?

As of October 2025, prices for Myrtle Beach to San Antonio flights are approximately 334% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to San Antonio (MYR to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to San Antonio

Direct flights

None
There are no direct flights from Myrtle Beach to San Antonio. There are no popular flight routes from Myrtle Beach to San Antonio.
Search flight deals

  • How far is Myrtle Beach Intl to San Antonio by plane?

    There are 1188.5 mi between Myrtle Beach Intl and San Antonio. A reasonable flight in good conditions will take 5h 00m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to San Antonio Airport?

    Prices for flights from Myrtle Beach Intl Airport to San Antonio Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to San Antonio Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to San Antonio Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The required travel and health documents for your San Antonio Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Antonio Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to San Antonio?

Best airlines flying from Myrtle Beach to San Antonio

Compare and see reviews for airlines that fly from Myrtle Beach to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $193Free CancellationRating
6.3
8,070 reviews
Search Spirit Airlines flights
DeltaPriceFrom $286Free CancellationRating
7.9
7,962 reviews
Search Delta flights
SouthwestPriceFrom $340Free CancellationRating
8.0
4,248 reviews
Search Southwest flights
American AirlinesPriceFrom $345Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville
Boerne
Schertz
Pleasanton

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to San Antonio?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Antonio from Myrtle Beach.

Can I find flights from Myrtle Beach to San Antonio with flexible booking policies on momondo?

Yes. All flights to San Antonio from Myrtle Beach on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Myrtle Beach to San Antonio?

momondo provides multiple filters to help you find the best flight to San Antonio from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to San Antonio right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Antonio, momondo offers a useful price alert feature which will track prices for flights to San Antonio from Myrtle Beach and alert you when they change.

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