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Cheap flights from Myrtle Beach to San Antonio from $292

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to San Antonio departing on 5/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to San Antonio

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
7:15 pm - 11:55 pm
MYR
-
SAT
5h 40m
1 stop
Southwest Logo
2:00 pm - 9:45 pm
SAT
-
MYR
6h 45m
1 stop
$371Southwest
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
6:06 pm - 11:59 pm
MYR
-
SAT
6h 53m
2 stops
American Airlines Logo
8:00 am - 3:45 pm
SAT
-
MYR
6h 45m
1 stop
$376American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
6:06 pm - 11:59 pm
MYR
-
SAT
6h 53m
2 stops
American Airlines Logo
5:01 am - 12:32 pm
SAT
-
MYR
6h 31m
2 stops
$395American Airlines
Tue, Jun 16 - Tue, Jun 23
Southwest Logo
7:15 pm - 12:10 am
MYR
-
SAT
5h 55m
1 stop
Southwest Logo
1:50 pm - 9:20 pm
SAT
-
MYR
6h 30m
1 stop
$397Southwest
Sat, Jun 13 - Mon, Jun 15
Southwest Logo
11:15 am - 4:15 pm
MYR
-
SAT
6h 00m
1 stop
Southwest Logo
11:50 am - 9:10 pm
SAT
-
MYR
8h 20m
1 stop
$399Southwest
Wed, May 27 - Wed, Jun 10
Southwest Logo
2:10 pm - 10:00 pm
MYR
-
SAT
8h 50m
2 stops
Southwest Logo
2:00 pm - 9:45 pm
SAT
-
MYR
6h 45m
1 stop
$404Southwest
Wed, May 27 - Wed, Jun 10
Southwest Logo
7:50 am - 3:45 pm
MYR
-
SAT
8h 55m
2 stops
Southwest Logo
5:10 am - 6:35 pm
SAT
-
MYR
12h 25m
1 stop
$408Southwest
Thu, Jul 2 - Mon, Jul 6
Southwest Logo
7:15 pm - 11:55 pm
MYR
-
SAT
5h 40m
1 stop
Southwest Logo
12:25 pm - 8:30 pm
SAT
-
MYR
7h 05m
1 stop
$409Southwest
Tue, Jun 9 - Thu, Jun 11
Delta Logo
6:00 am - 11:10 am
MYR
-
SAT
6h 10m
1 stop
Delta Logo
6:45 am - 1:38 pm
SAT
-
MYR
5h 53m
1 stop
$412Delta
Mon, Sep 14 - Sun, Sep 20
Southwest Logo
8:30 am - 5:55 pm
MYR
-
SAT
10h 25m
1 stop
Southwest Logo
11:45 am - 9:20 pm
SAT
-
MYR
8h 35m
2 stops
$420Southwest
Tue, Jun 16 - Fri, Jun 19

Southwest flights from Myrtle Beach to San Antonio

Our best Southwest deals on Myrtle Beach to San Antonio flight tickets
Southwest
Jun 16
MYR7:15 pmMyrtle Beach Intl
5h 40m
1 stop
SAT11:55 pmSan Antonio
Jun 23
SAT8:20 amSan Antonio
9h 15m
1 stop
MYR6:35 pmMyrtle Beach Intl
$371
Southwest
Jun 13
MYR7:15 pmMyrtle Beach Intl
5h 55m
1 stop
SAT12:10 amSan Antonio
Jun 15
SAT1:50 pmSan Antonio
6h 30m
1 stop
MYR9:20 pmMyrtle Beach Intl
$397
Southwest
May 27
MYR11:15 amMyrtle Beach Intl
6h 00m
1 stop
SAT4:15 pmSan Antonio
Jun 10
SAT11:50 amSan Antonio
8h 20m
1 stop
MYR9:10 pmMyrtle Beach Intl
$399

American Airlines flights from Myrtle Beach to San Antonio

Our best American Airlines deals on Myrtle Beach to San Antonio flight tickets
American Airlines
Jun 16
MYR6:06 pmMyrtle Beach Intl
6h 53m
2 stops
SAT11:59 pmSan Antonio
Jun 23
SAT8:00 amSan Antonio
6h 45m
1 stop
MYR3:45 pmMyrtle Beach Intl
$376
American Airlines
Jun 16
MYR6:06 pmMyrtle Beach Intl
6h 53m
2 stops
SAT11:59 pmSan Antonio
Jun 23
SAT5:01 amSan Antonio
6h 31m
2 stops
MYR12:32 pmMyrtle Beach Intl
$395
American Airlines
Jul 10
MYR4:42 pmMyrtle Beach Intl
7h 23m
1 stop
SAT11:05 pmSan Antonio
Jul 12
SAT7:00 amSan Antonio
7h 31m
2 stops
MYR3:31 pmMyrtle Beach Intl
$673

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 6/16

7:15 pm-11:55 pm

1 stop5h 40m

San Antonio

Tue 6/23

2:00 pm-9:45 pm

1 stop6h 45m

$371

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 6/16

6:06 pm-11:59 pm

2 stops6h 53m

San Antonio

Tue 6/23

8:00 am-3:45 pm

1 stop6h 45m

$376

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 6/16

6:06 pm-11:59 pm

2 stops6h 53m

San Antonio

Tue 6/23

5:01 am-12:32 pm

2 stops6h 31m

$395

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Sat 6/13

7:15 pm-12:10 am

1 stop5h 55m

San Antonio

Mon 6/15

1:50 pm-9:20 pm

1 stop6h 30m

$397

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Wed 5/27

11:15 am-4:15 pm

1 stop6h 00m

San Antonio

Wed 6/10

11:50 am-9:10 pm

1 stop8h 20m

$399

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Wed 5/27

2:10 pm-10:00 pm

2 stops8h 50m

San Antonio

Wed 6/10

2:00 pm-9:45 pm

1 stop6h 45m

$404

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Thu 7/2

7:50 am-3:45 pm

2 stops8h 55m

San Antonio

Mon 7/6

5:10 am-6:35 pm

1 stop12h 25m

$408

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 6/9

7:15 pm-11:55 pm

1 stop5h 40m

San Antonio

Thu 6/11

12:25 pm-8:30 pm

1 stop7h 05m

$409
Quickest round-trip

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Mon 9/14

6:00 am-11:10 am

1 stop6h 10m

San Antonio

Sun 9/20

6:45 am-1:38 pm

1 stop5h 53m

$412

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 6/16

8:30 am-5:55 pm

1 stop10h 25m

San Antonio

Fri 6/19

11:45 am-9:20 pm

2 stops8h 35m

$420

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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2

See travel insights to San Antonio from

How to get the cheapest flight ticket from Myrtle Beach to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and San Antonio?

What is the cheapest month to fly to San Antonio?

If you aren’t able to travel during the month of August, then book flights to San Antonio from Myrtle Beach during May instead. Flights to San Antonio in May, while not as cheap as those in August, still average around $315.

How have Myrtle Beach to San Antonio flight prices changed over time?

When to book flights from Myrtle Beach to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to San Antonio (MYR to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to San Antonio

Fastest flight time

5h 36m

Direct flights

None
The fastest flight from Myrtle Beach to San Antonio takes 5h 36m
There are no direct flights from Myrtle Beach to San Antonio. There are no popular flight routes from Myrtle Beach to San Antonio.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to San Antonio

  • How far is Myrtle Beach Intl to San Antonio by plane?

    There are 1188.5 mi between Myrtle Beach Intl and San Antonio. A reasonable flight in good conditions will take 5h 36m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to San Antonio Airport?

    Prices for flights from Myrtle Beach Intl Airport to San Antonio Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to San Antonio Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to San Antonio Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The required travel and health documents for your San Antonio Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Antonio Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to San Antonio?

Best airlines flying from Myrtle Beach to San Antonio

Compare and see reviews for airlines that fly from Myrtle Beach to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $273Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights
DeltaPriceFrom $286Free CancellationRating
7.9
8,455 reviews
Search Delta flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville
Boerne
Pleasanton
Schertz

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to San Antonio?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Antonio from Myrtle Beach.

Can I find flights from Myrtle Beach to San Antonio with flexible booking policies on momondo?

Yes. All flights to San Antonio from Myrtle Beach on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Myrtle Beach to San Antonio?

momondo provides multiple filters to help you find the best flight to San Antonio from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to San Antonio right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Antonio, momondo offers a useful price alert feature which will track prices for flights to San Antonio from Myrtle Beach and alert you when they change.

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