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Cheap flights from La Crosse to San Diego from $358

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to San Diego departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:37 pm - 11:33 pm
LSE
-
SAN
6h 56m
1 stop
American Airlines Logo
10:40 pm - 9:35 am
SAN
-
LSE
8h 55m
1 stop
$358American Airlines
Mon, Apr 20 - Sat, Apr 25
American Airlines Logo
6:37 pm - 11:33 pm
LSE
-
SAN
6h 56m
1 stop
American Airlines Logo
7:20 pm - 9:35 am
SAN
-
LSE
12h 15m
2 stops
$364American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
10:05 am - 9:55 pm
LSE
-
SAN
13h 50m
2 stops
American Airlines Logo
7:20 pm - 9:35 am
SAN
-
LSE
12h 15m
2 stops
$369American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
7:15 pm - 11:22 am
SAN
-
LSE
14h 07m
2 stops
$427American Airlines
Wed, Jun 3 - Mon, Jun 8
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
6:15 am - 5:04 pm
SAN
-
LSE
8h 49m
1 stop
$428American Airlines
Wed, Jun 3 - Mon, Jun 8
American Airlines Logo
6:37 pm - 11:33 pm
LSE
-
SAN
6h 56m
1 stop
American Airlines Logo
7:20 pm - 9:35 am
SAN
-
LSE
12h 15m
2 stops
$434American Airlines
Mon, Apr 20 - Sat, Apr 25
American Airlines Logo
6:00 am - 2:20 pm
LSE
-
SAN
10h 20m
2 stops
American Airlines Logo
9:25 pm - 11:22 am
SAN
-
LSE
11h 57m
2 stops
$439American Airlines
Sat, May 30 - Tue, Jun 30
American Airlines Logo
6:37 pm - 11:33 pm
LSE
-
SAN
6h 56m
1 stop
American Airlines Logo
10:40 pm - 9:35 am
SAN
-
LSE
8h 55m
1 stop
$458American Airlines
Tue, Apr 21 - Sun, Apr 26
American Airlines Logo
5:35 pm - 11:28 pm
LSE
-
SAN
7h 53m
1 stop
American Airlines Logo
1:11 pm - 11:59 pm
SAN
-
LSE
8h 48m
1 stop
$463American Airlines
Thu, Jul 30 - Mon, Aug 3
American Airlines Logo
10:05 am - 8:50 pm
LSE
-
SAN
12h 45m
2 stops
American Airlines Logo
3:09 pm - 11:54 pm
SAN
-
LSE
6h 45m
1 stop
$464American Airlines
Wed, Apr 22 - Wed, Apr 29

American Airlines flights from La Crosse to San Diego

Our best American Airlines deals on La Crosse to San Diego flight tickets
American Airlines
Apr 20
LSE6:37 pmLa Crosse
6h 56m
1 stop
SAN11:33 pmSan Diego
Apr 25
SAN10:40 pmSan Diego
8h 55m
1 stop
LSE9:35 amLa Crosse
$358
American Airlines
Apr 24
LSE6:37 pmLa Crosse
6h 56m
1 stop
SAN11:33 pmSan Diego
Apr 27
SAN7:20 pmSan Diego
12h 15m
2 stops
LSE9:35 amLa Crosse
$364
American Airlines
Apr 24
LSE10:05 amLa Crosse
13h 50m
2 stops
SAN9:55 pmSan Diego
Apr 27
SAN7:20 pmSan Diego
12h 15m
2 stops
LSE9:35 amLa Crosse
$369

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Mon 4/20

6:37 pm-11:33 pm

1 stop6h 56m

San Diego

Sat 4/25

10:40 pm-9:35 am

1 stop8h 55m

$358

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Fri 4/24

6:37 pm-11:33 pm

1 stop6h 56m

San Diego

Mon 4/27

7:20 pm-9:35 am

2 stops12h 15m

$364

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Fri 4/24

10:05 am-9:55 pm

2 stops13h 50m

San Diego

Mon 4/27

7:20 pm-9:35 am

2 stops12h 15m

$369

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 6/3

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Mon 6/8

7:15 pm-11:22 am

2 stops14h 07m

$427

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 6/3

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Mon 6/8

6:15 am-5:04 pm

1 stop8h 49m

$428

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Mon 4/20

6:37 pm-11:33 pm

1 stop6h 56m

San Diego

Sat 4/25

7:20 pm-9:35 am

2 stops12h 15m

$434

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Sat 5/30

6:00 am-2:20 pm

2 stops10h 20m

San Diego

Tue 6/30

9:25 pm-11:22 am

2 stops11h 57m

$439

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Tue 4/21

6:37 pm-11:33 pm

1 stop6h 56m

San Diego

Sun 4/26

10:40 pm-9:35 am

1 stop8h 55m

$458

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 7/30

5:35 pm-11:28 pm

1 stop7h 53m

San Diego

Mon 8/3

1:11 pm-11:59 pm

1 stop8h 48m

$463

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 4/22

10:05 am-8:50 pm

2 stops12h 45m

San Diego

Wed 4/29

3:09 pm-11:54 pm

1 stop6h 45m

$464

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Diego from

How to get the cheapest flight ticket from La Crosse to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to San Diego?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Diego from La Crosse according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 3 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When to book flights from La Crosse to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to San Diego (LSE to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to San Diego

Fastest flight time

8h 33m

Direct flights

None
The fastest flight from La Crosse to San Diego takes 8h 33m
There are no direct flights from La Crosse to San Diego. There are no popular flight routes from La Crosse to San Diego.
Search flight deals

  • How far is La Crosse to San Diego by plane?

    A flight from La Crosse to San Diego will travel around 1590.5 mi. Flights usually cover this in 8h 33m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from La Crosse Airport to San Diego Airport?

    Prices for flights from La Crosse Airport to San Diego Airport refresh daily.

  • How old do you have to be to fly from La Crosse Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
Imperial Beach
La Mesa
Borrego Springs
Alpine
Santee
Lemon Grove

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from La Crosse to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from La Crosse to San Diego with flexible booking policies on momondo?

Flights from La Crosse to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from La Crosse to San Diego?

Once all potential La Crosse to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from La Crosse to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from La Crosse to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

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