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Cheap flights from La Crosse to San Diego from $408

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to San Diego departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from La Crosse to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
6:15 am - 5:04 pm
SAN
-
LSE
8h 49m
1 stop
$408American Airlines
Tue, May 26 - Sat, May 30
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
9:54 am - 12:06 am
SAN
-
LSE
12h 12m
2 stops
$414American Airlines
Tue, May 26 - Sat, May 30
American Airlines Logo
5:53 pm - 11:26 pm
LSE
-
SAN
7h 33m
1 stop
American Airlines Logo
6:15 am - 5:23 pm
SAN
-
LSE
9h 08m
1 stop
$423American Airlines
Thu, Jul 30 - Mon, Aug 3
American Airlines Logo
5:53 pm - 11:26 pm
LSE
-
SAN
7h 33m
1 stop
American Airlines Logo
10:28 pm - 11:31 am
SAN
-
LSE
11h 03m
2 stops
$429American Airlines
Thu, Jul 30 - Mon, Aug 3
American Airlines Logo
5:53 pm - 11:26 pm
LSE
-
SAN
7h 33m
1 stop
American Airlines Logo
10:28 pm - 11:31 am
SAN
-
LSE
11h 03m
2 stops
$444American Airlines
Thu, Jul 30 - Mon, Aug 3
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
1:19 pm - 12:06 am
SAN
-
LSE
8h 47m
1 stop
$453American Airlines
Fri, May 22 - Wed, May 27
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
9:25 pm - 11:22 am
SAN
-
LSE
11h 57m
2 stops
$459American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
5:34 pm - 11:39 pm
LSE
-
SAN
8h 05m
1 stop
American Airlines Logo
6:17 am - 4:58 pm
SAN
-
LSE
8h 41m
1 stop
$484American Airlines
Mon, Jun 1 - Sun, Jun 7
American Airlines Logo
3:13 pm - 9:17 pm
LSE
-
SAN
8h 04m
1 stop
American Airlines Logo
1:21 pm - 11:15 pm
SAN
-
LSE
7h 54m
1 stop
$494American Airlines
Sat, Aug 22 - Fri, Sep 25
American Airlines Logo
3:13 pm - 9:17 pm
LSE
-
SAN
8h 04m
1 stop
American Airlines Logo
1:21 pm - 11:15 pm
SAN
-
LSE
7h 54m
2 stops
$499American Airlines
Sat, Aug 22 - Fri, Sep 25

American Airlines flights from La Crosse to San Diego

Our best American Airlines deals on La Crosse to San Diego flight tickets
American Airlines
May 26
LSE5:34 pmLa Crosse
8h 05m
1 stop
SAN11:39 pmSan Diego
May 30
SAN6:15 amSan Diego
8h 49m
1 stop
LSE5:04 pmLa Crosse
$408
American Airlines
May 26
LSE5:34 pmLa Crosse
8h 05m
1 stop
SAN11:39 pmSan Diego
May 30
SAN9:54 amSan Diego
12h 12m
2 stops
LSE12:06 amLa Crosse
$414
American Airlines
Jul 30
LSE5:53 pmLa Crosse
7h 33m
1 stop
SAN11:26 pmSan Diego
Aug 3
SAN6:15 amSan Diego
9h 08m
1 stop
LSE5:23 pmLa Crosse
$423

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Tue 5/26

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Sat 5/30

6:15 am-5:04 pm

1 stop8h 49m

$408

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Tue 5/26

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Sat 5/30

9:54 am-12:06 am

2 stops12h 12m

$414

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 7/30

5:53 pm-11:26 pm

1 stop7h 33m

San Diego

Mon 8/3

6:15 am-5:23 pm

1 stop9h 08m

$423

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 7/30

5:53 pm-11:26 pm

1 stop7h 33m

San Diego

Mon 8/3

10:28 pm-11:31 am

2 stops11h 03m

$429

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 7/30

5:53 pm-11:26 pm

1 stop7h 33m

San Diego

Mon 8/3

10:28 pm-11:31 am

2 stops11h 03m

$444

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Fri 5/22

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Wed 5/27

1:19 pm-12:06 am

1 stop8h 47m

$453

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Fri 5/22

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Tue 5/26

9:25 pm-11:22 am

2 stops11h 57m

$459

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Mon 6/1

5:34 pm-11:39 pm

1 stop8h 05m

San Diego

Sun 6/7

6:17 am-4:58 pm

1 stop8h 41m

$484
Quickest round-trip

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Sat 8/22

3:13 pm-9:17 pm

1 stop8h 04m

San Diego

Fri 9/25

1:21 pm-11:15 pm

1 stop7h 54m

$494

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Sat 8/22

3:13 pm-9:17 pm

1 stop8h 04m

San Diego

Fri 9/25

1:21 pm-11:15 pm

2 stops7h 54m

$499

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Diego from

How to get the cheapest flight ticket from La Crosse to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to San Diego?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Diego from La Crosse according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 3 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When to book flights from La Crosse to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to San Diego (LSE to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to San Diego

Fastest flight time

6h 57m

Direct flights

None
The fastest flight from La Crosse to San Diego takes 6h 57m
There are no direct flights from La Crosse to San Diego. There are no popular flight routes from La Crosse to San Diego.
Search flight deals

Frequently asked questions about flying from La Crosse to San Diego

  • How far is La Crosse to San Diego by plane?

    A flight from La Crosse to San Diego will travel around 1590.5 mi. Flights usually cover this in 6h 57m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from La Crosse Airport to San Diego Airport?

    Prices for flights from La Crosse Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from La Crosse Airport to San Diego Airport?

  • How old do you have to be to fly from La Crosse Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from La Crosse to San Diego?

Best airlines flying from La Crosse to San Diego

Compare and see reviews for airlines that fly from La Crosse to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $358Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from La Crosse to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from La Crosse to San Diego with flexible booking policies on momondo?

Flights from La Crosse to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from La Crosse to San Diego?

Once all potential La Crosse to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from La Crosse to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from La Crosse to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

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