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Cheap flights from La Crosse to San Diego from $453

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to San Diego departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from La Crosse to San Diego

Cheap round-trip flights

American Airlines Logo
6:00 am - 12:30 pmLSE-SAN
8h 30m1 stop
American Airlines Logo
6:15 am - 5:32 pmSAN-LSE
9h 17m1 stop
$474American Airlines
Find Deal
Thu, Dec 11 - Sat, Dec 13
American Airlines Logo
6:00 am - 12:30 pmLSE-SAN
8h 30m1 stop
American Airlines Logo
10:09 am - 11:52 pmSAN-LSE
11h 43m2 stops
$480American Airlines
Find Deal
Thu, Dec 11 - Sat, Dec 13
American Airlines Logo
9:46 am - 6:32 pmLSE-SAN
10h 46m2 stops
American Airlines Logo
10:47 am - 11:52 pmSAN-LSE
11h 05m2 stops
$485American Airlines
Find Deal
Thu, Dec 11 - Sat, Dec 13

American Airlines flights from La Crosse to San Diego

Our best American Airlines deals on La Crosse to San Diego flight tickets
American Airlines
Dec 11
LSE6:00 amLa Crosse
8h 30m
1 stop
SAN12:30 pmSan Diego
Dec 13
SAN6:15 amSan Diego
9h 17m
1 stop
LSE5:32 pmLa Crosse
$474
Find similar
American Airlines
Dec 11
LSE6:00 amLa Crosse
8h 30m
1 stop
SAN12:30 pmSan Diego
Dec 13
SAN10:09 amSan Diego
11h 43m
2 stops
LSE11:52 pmLa Crosse
$480
Find similar
American Airlines
Dec 11
LSE9:46 amLa Crosse
10h 46m
2 stops
SAN6:32 pmSan Diego
Dec 13
SAN10:47 amSan Diego
11h 05m
2 stops
LSE11:52 pmLa Crosse
$485
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 12/11

6:00 am-12:30 pm

1 stop8h 30m

San Diego

Sat 12/13

6:15 am-5:32 pm

1 stop9h 17m

$474

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 12/11

6:00 am-12:30 pm

1 stop8h 30m

San Diego

Sat 12/13

10:09 am-11:52 pm

2 stops11h 43m

$480

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 12/11

9:46 am-6:32 pm

2 stops10h 46m

San Diego

Sat 12/13

10:47 am-11:52 pm

2 stops11h 05m

$485

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 10/1

6:00 am-12:27 pm

1 stop8h 27m

$453

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 10/1

6:00 am-3:53 pm

2 stops11h 53m

$459

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 10/1

6:00 am-12:27 pm

1 stop8h 27m

$485

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 10/1

6:00 am-3:21 pm

2 stops11h 21m

$491

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 10/1

6:00 am-3:53 pm

2 stops11h 53m

$537

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from La Crosse to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from La Crosse to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $640. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $660. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $619. Flights in the morning are often more expensive with an average ticket price of $660.

When to book flights from La Crosse to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to San Diego (LSE to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to San Diego

Direct flights

None
There are no direct flights from La Crosse to San Diego. There are no popular flight routes from La Crosse to San Diego.
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  • How far is La Crosse to San Diego by plane?

    A flight from La Crosse to San Diego will travel around 1590.5 mi. Flights usually cover this in 8h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from La Crosse Airport to San Diego Airport?

    Prices for flights from La Crosse Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from La Crosse Airport to San Diego Airport?

  • How old do you have to be to fly from La Crosse Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from La Crosse to San Diego?

Best airlines flying from La Crosse to San Diego

Compare and see reviews for airlines that fly from La Crosse to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $474Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Poway
Imperial Beach
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from La Crosse to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from La Crosse to San Diego with flexible booking policies on momondo?

Flights from La Crosse to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from La Crosse to San Diego?

Once all potential La Crosse to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from La Crosse to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from La Crosse to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

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1 adult
Wed 10/22
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