Cheap flights from Istanbul to San Francisco from $539

If you aren’t able to travel to San Francisco during the month of January, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $482.

The cheapest day to depart from Istanbul to San Francisco is on a Thursday when prices can be found for as low as $829. The most expensive day to fly to San Francisco is Saturday, with ticket prices averaging around $1,269.

Our data shows that the cheapest Istanbul to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $887. Flights at noon are often more expensive with an average ticket price of $904.

Fly from Istanbul to San Francisco for the best Istanbul - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Istanbul when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $862 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Istanbul for as low as $590 on momondo.

There are 2 cabin classes available to choose from on Istanbul to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

SAUDIA, United Airlines, and KLM are the most popular carriers operating from Istanbul to San Francisco

Turkish Airlines, Lufthansa and KLM are the top three most popular airlines that fly to San Francisco from Istanbul according to our data. Turkish Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 19% of flights between Istanbul and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 88 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, Turkish Airlines have had the least number of delays on this route over the last 12 months; with about 19% of their flights experiencing any sort of delay.

4 flights are operational daily from Istanbul to San Francisco as of July 2026. The most popular departure time for this route is 1:00PM, with 70% of flights per day taking off in the afternoon.

30 flights are operational weekly from Istanbul to San Francisco as of July 2026. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.