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Cheap flights from Iowa to San Francisco from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to San Francisco departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Iowa to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:14 pm - 8:05 pm
DSM
-
SFO
25h 51m
1 stop
Frontier Logo
6:00 am - 7:14 pm
SFO
-
DSM
11h 14m
1 stop
$181Frontier
E, apr 6 - E, apr 13
Frontier Logo
8:49 pm - 12:27 am
OMA
-
SFO
5h 38m
1 stop
Frontier Logo
6:00 am - 8:13 pm
SFO
-
OMA
12h 13m
1 stop
$185Frontier
R, apr 17 - E, apr 20
Frontier Logo
2:16 pm - 12:23 am
DSM
-
SFO
12h 07m
1 stop
Frontier Logo
6:00 am - 1:31 pm
SFO
-
DSM
5h 31m
1 stop
$185Frontier
K, mai 6 - K, mai 13
Frontier Logo
2:16 pm - 12:23 am
DSM
-
SFO
12h 07m
1 stop
Frontier Logo
6:00 am - 1:31 pm
SFO
-
DSM
5h 31m
1 stop
$186Frontier
K, mai 6 - K, mai 13
Multiple Airlines Logo
9:55 pm - 9:39 pm
MLI
-
SFO
25h 44m
2 stops
Multiple Airlines Logo
2:47 pm - 11:29 am
SFO
-
MLI
18h 42m
1 stop
$235Multiple Airlines
E, apr 27 - K, apr 29
Multiple Airlines Logo
10:10 pm - 10:30 am
CID
-
SFO
14h 20m
1 stop
Multiple Airlines Logo
10:04 pm - 12:21 pm
SFO
-
CID
36h 17m
2 stops
$264Multiple Airlines
E, juuni 1 - R, juuni 5
American Airlines Logo
6:40 pm - 11:59 pm
MLI
-
SFO
7h 19m
1 stop
American Airlines Logo
1:30 pm - 11:54 pm
SFO
-
MLI
8h 24m
1 stop
$331American Airlines
K, mai 13 - L, mai 16
United Airlines Logo
7:11 pm - 1:42 am
LSE
-
SFO
8h 31m
1 stop
United Airlines Logo
11:30 pm - 8:56 am
SFO
-
LSE
7h 26m
1 stop
$358United Airlines
P, juuni 21 - E, aug 10
American Airlines Logo
3:48 pm - 10:00 pm
MLI
-
SFO
8h 12m
1 stop
American Airlines Logo
12:30 am - 12:27 pm
SFO
-
MLI
9h 57m
1 stop
$369American Airlines
R, apr 17 - N, apr 23
United Airlines Logo
6:34 pm - 12:30 am
MLI
-
SFO
7h 56m
1 stop
United Airlines Logo
5:05 am - 1:56 pm
SFO
-
MLI
6h 51m
1 stop
$381United Airlines
L, juuni 6 - K, juuni 10

United Airlines flights from Iowa to San Francisco

Our best United Airlines deals on Iowa to San Francisco flight tickets
United Airlines
Jun 21
LSE7:11 pmLa Crosse
8h 31m
1 stop
SFO1:42 amSan Francisco
Aug 10
SFO11:30 pmSan Francisco
7h 26m
1 stop
LSE8:56 amLa Crosse
$358
United Airlines
May 12
CID3:13 pmCedar Rapids
6h 39m
1 stop
SFO7:52 pmSan Francisco
May 18
SFO12:45 amSan Francisco
7h 42m
1 stop
CID10:27 amCedar Rapids
$367
United Airlines
Apr 14
CID4:46 pmCedar Rapids
8h 09m
1 stop
SFO10:55 pmSan Francisco
Apr 22
SFO6:40 amSan Francisco
5h 33m
1 stop
CID2:13 pmCedar Rapids
$369

Delta flights from Iowa to San Francisco

Our best Delta deals on Iowa to San Francisco flight tickets
Delta
Apr 10
OMA5:50 pmOmaha Eppley Airfield
8h 09m
1 stop
SFO11:59 pmSan Francisco
Apr 11
SFO6:20 amSan Francisco
8h 26m
1 stop
OMA4:46 pmOmaha Eppley Airfield
$389
Delta
Jul 14
CID12:09 pmCedar Rapids
7h 03m
1 stop
SFO5:12 pmSan Francisco
Jul 20
SFO12:51 amSan Francisco
8h 35m
1 stop
CID11:26 amCedar Rapids
$399
Delta
Jul 4
CID4:24 pmCedar Rapids
6h 18m
1 stop
SFO8:42 pmSan Francisco
Jul 6
SFO3:26 pmSan Francisco
5h 23m
1 stop
CID10:49 pmCedar Rapids
$400

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated märts 27, 2026.
Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

E 4/6

8:14 pm-8:05 pm

1 stop25h 51m

San Francisco

E 4/13

6:00 am-7:14 pm

1 stop11h 14m

$181

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

R 4/17

8:49 pm-12:27 am

1 stop5h 38m

San Francisco

E 4/20

6:00 am-8:13 pm

1 stop12h 13m

$185

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

K 5/6

2:16 pm-12:23 am

1 stop12h 07m

San Francisco

K 5/13

6:00 am-1:31 pm

1 stop5h 31m

$185

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

K 5/6

2:16 pm-12:23 am

1 stop12h 07m

San Francisco

K 5/13

6:00 am-1:31 pm

1 stop5h 31m

$186

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

E 4/27

9:55 pm-9:39 pm

2 stops25h 44m

San Francisco

K 4/29

2:47 pm-11:29 am

1 stop18h 42m

$235

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

E 6/1

10:10 pm-10:30 am

1 stop14h 20m

San Francisco

R 6/5

10:04 pm-12:21 pm

2 stops36h 17m

$264

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

K 5/13

6:40 pm-11:59 pm

1 stop7h 19m

San Francisco

L 5/16

1:30 pm-11:54 pm

1 stop8h 24m

$331

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

P 6/21

7:11 pm-1:42 am

1 stop8h 31m

San Francisco

E 8/10

11:30 pm-8:56 am

1 stop7h 26m

$358

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

R 4/17

3:48 pm-10:00 pm

1 stop8h 12m

San Francisco

N 4/23

12:30 am-12:27 pm

1 stop9h 57m

$369
Quickest round-trip

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

L 6/6

6:34 pm-12:30 am

1 stop7h 56m

San Francisco

K 6/10

5:05 am-1:56 pm

1 stop6h 51m

$381

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Iowa to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $366.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $427 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Iowa for as low as $351 on momondo.

Cheap Iowa to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to San Francisco

Fastest flight time

3h 44m

Direct flights

Every day

Airports in San Francisco

1 airport
The fastest flight from Iowa to San Francisco takes 3h 44m
Direct flights go from Iowa to San Francisco every day.
There is 1 airport in San Francisco. From Iowa there are direct flights to San Francisco (SFO).
Search flight deals

  • When did momondo last update prices for flights from Iowa to San Francisco Airport?

    Prices for flights from Iowa to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to San Francisco Airport?

  • How old do you have to be to fly from Iowa to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to San Francisco

Compare and see reviews for airlines that fly from Iowa to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $129Free CancellationRating
5.7
3,014 reviews
Search Frontier flights
DeltaPriceFrom $243Free CancellationRating
7.9
8,341 reviews
Search Delta flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
9,491 reviews
Search United Airlines flights
American AirlinesPriceFrom $288Free CancellationRating
7.1
11,507 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
8.0
4,331 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Daly City
Half Moon Bay
Milpitas
South San Francisco
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to San Francisco with flexible booking policies on momondo?

All flight searches from Iowa to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to San Francisco?

momondo helps you find the best flight between Iowa and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Iowa to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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P 4/26
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