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Cheap flights from Iowa to San Francisco from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to San Francisco departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:32 pm - 12:28 am
DSM
-
SFO
6h 56m1 stop
Frontier Logo
8:48 am - 6:47 pm
SFO
-
DSM
7h 59m1 stop
$165Frontier
to, helmi 12 - to, helmi 19
Frontier Logo
7:32 pm - 12:28 am
DSM
-
SFO
6h 56m1 stop
Frontier Logo
8:48 am - 6:47 pm
SFO
-
DSM
7h 59m1 stop
$182Frontier
to, helmi 12 - to, helmi 19
Alaska Airlines Logo
3:07 pm - 11:03 pm
OMA
-
SFO
9h 56m1 stop
Alaska Airlines Logo
12:00 pm - 2:11 pm
SFO
-
OMA
24h 11m1 stop
$228Alaska Airlines
ke, tammi 21 - ke, helmi 4
Delta Logo
5:06 pm - 11:25 pm
MLI
-
SFO
8h 19m1 stop
Delta Logo
6:00 am - 4:26 pm
SFO
-
MLI
8h 26m1 stop
$241Delta
la, tammi 17 - ti, tammi 20
United Airlines Logo
7:28 am - 9:45 am
OMA
-
SFO
4h 17mnonstop
United Airlines Logo
4:22 pm - 9:53 pm
SFO
-
OMA
3h 31mnonstop
$249United Airlines
to, tammi 15 - ma, tammi 19
Multiple Airlines Logo
3:11 pm - 7:31 am
OMA
-
SFO
18h 20m2 stops
Multiple Airlines Logo
8:48 am - 6:34 pm
SFO
-
OMA
7h 46m1 stop
$253Multiple Airlines
ti, helmi 17 - ma, helmi 23
Alaska Airlines Logo
3:11 pm - 10:56 pm
OMA
-
SFO
9h 45m1 stop
Alaska Airlines Logo
7:28 pm - 2:15 pm
SFO
-
OMA
16h 47m1 stop
$258Alaska Airlines
ma, helmi 23 - la, helmi 28
United Airlines Logo
7:23 am - 9:45 am
OMA
-
SFO
4h 22mnonstop
United Airlines Logo
10:50 pm - 10:29 am
SFO
-
OMA
9h 39m1 stop
$259United Airlines
ti, helmi 17 - ma, helmi 23
Delta Logo
5:06 pm - 11:25 pm
MLI
-
SFO
8h 19m1 stop
Delta Logo
6:00 am - 4:26 pm
SFO
-
MLI
8h 26m1 stop
$275Delta
la, tammi 17 - la, tammi 24
Multiple Airlines Logo
7:15 am - 10:24 am
DBQ
-
SFO
29h 09m2 stops
Multiple Airlines Logo
6:12 pm - 8:40 pm
SFO
-
DBQ
24h 28m3 stops
$1,391Multiple Airlines
ma, joulu 29 - pe, tammi 2

Frontier flights from Iowa to San Francisco

Our best Frontier deals on Iowa to San Francisco flight tickets
Frontier
Feb 25
OMA5:00 pmOmaha Eppley Airfield
17h 03m
1 stop
SFO8:03 amSan Francisco
Mar 2
SFO8:48 amSan Francisco
7h 46m
1 stop
OMA6:34 pmOmaha Eppley Airfield
$155
Find similar
Frontier
Feb 12
DSM7:32 pmDes Moines
6h 56m
1 stop
SFO12:28 amSan Francisco
Feb 19
SFO8:48 amSan Francisco
7h 59m
1 stop
DSM6:47 pmDes Moines
$182
Find similar
Frontier
Jan 8
CID8:15 pmCedar Rapids
13h 48m
1 stop
SFO8:03 amSan Francisco
Jan 15
SFO6:15 amSan Francisco
10h 58m
1 stop
CID7:13 pmCedar Rapids
$183
Find similar

Alaska Airlines flights from Iowa to San Francisco

Our best Alaska Airlines deals on Iowa to San Francisco flight tickets
Alaska Airlines
Feb 5
OMA3:07 pmOmaha Eppley Airfield
8h 51m
1 stop
SFO9:58 pmSan Francisco
Feb 10
SFO7:40 pmSan Francisco
16h 31m
1 stop
OMA2:11 pmOmaha Eppley Airfield
$228
Find similar
Alaska Airlines
Mar 5
OMA3:11 pmOmaha Eppley Airfield
9h 45m
1 stop
SFO10:56 pmSan Francisco
Mar 9
SFO8:47 pmSan Francisco
15h 28m
1 stop
OMA2:15 pmOmaha Eppley Airfield
$258
Find similar
Alaska Airlines
Feb 4
OMA3:07 pmOmaha Eppley Airfield
7h 05m
1 stop
SFO8:12 pmSan Francisco
Feb 10
SFO7:40 pmSan Francisco
16h 31m
1 stop
OMA2:11 pmOmaha Eppley Airfield
$300
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated joulukuu 14, 2025.
Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

to 2/12

7:32 pm-12:28 am

1 stop6h 56m

San Francisco

to 2/19

8:48 am-6:47 pm

1 stop7h 59m

$165

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

to 2/12

7:32 pm-12:28 am

1 stop6h 56m

San Francisco

to 2/19

8:48 am-6:47 pm

1 stop7h 59m

$182

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

ke 1/21

3:07 pm-11:03 pm

1 stop9h 56m

San Francisco

ke 2/4

12:00 pm-2:11 pm

1 stop24h 11m

$228

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

la 1/17

5:06 pm-11:25 pm

1 stop8h 19m

San Francisco

ti 1/20

6:00 am-4:26 pm

1 stop8h 26m

$241

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

to 1/15

7:28 am-9:45 am

Nonstop4h 17m

San Francisco

ma 1/19

4:22 pm-9:53 pm

Nonstop3h 31m

$249

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

ti 2/17

3:11 pm-7:31 am

2 stops18h 20m

San Francisco

ma 2/23

8:48 am-6:34 pm

1 stop7h 46m

$253

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

ma 2/23

3:11 pm-10:56 pm

1 stop9h 45m

San Francisco

la 2/28

7:28 pm-2:15 pm

1 stop16h 47m

$258

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

ti 2/17

7:23 am-9:45 am

Nonstop4h 22m

San Francisco

ma 2/23

10:50 pm-10:29 am

1 stop9h 39m

$259

MolineSan Francisco

MLI - SFO

MLISFO

Moline Quad-City

la 1/17

5:06 pm-11:25 pm

1 stop8h 19m

San Francisco

la 1/24

6:00 am-4:26 pm

1 stop8h 26m

$275

DubuqueSan Francisco

DBQ - SFO

DBQSFO

Dubuque

ma 12/29

7:15 am-10:24 am

2 stops29h 09m

San Francisco

pe 1/2

6:12 pm-8:40 pm

3 stops24h 28m

$1,391

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Iowa to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of September, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $374.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Iowa to San Francisco is on a Friday when prices can be found for as low as $450. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $541.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Iowa to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $371. Flights at noon are often more expensive with an average ticket price of $471.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $438 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Iowa for as low as $347 on momondo.

Cheap Iowa to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to San Francisco

Fastest flight time

3h 50m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in San Francisco

1 airport
The fastest flight from Iowa to San Francisco takes 3h 50m
Direct flights go from Iowa to San Francisco on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in San Francisco. From Iowa there are direct flights to San Francisco (SFO).
Search flight deals

  • When did momondo last update prices for flights from Iowa to San Francisco Airport?

    Prices for flights from Iowa to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to San Francisco Airport?

  • How old do you have to be to fly from Iowa to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to San Francisco

Compare and see reviews for airlines that fly from Iowa to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $129Free CancellationRating
5.8
3,080 reviews
Search Frontier flights
DeltaPriceFrom $265Free CancellationRating
7.9
8,008 reviews
Search Delta flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
American AirlinesPriceFrom $288Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
SouthwestPriceFrom $336Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Berkeley
Santa Clara
Walnut Creek
Fremont
Daly City
Half Moon Bay
Vallejo
Salinas
Livermore
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to San Francisco with flexible booking policies on momondo?

All flight searches from Iowa to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to San Francisco?

momondo helps you find the best flight between Iowa and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Iowa to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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1 adult
ti 1/13
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