What is the cheapest airline that flies from Iowa to San Francisco?

Frontier, Alaska Airlines, and Southwest are the most popular carriers operating from Iowa to San Francisco

What airlines fly to San Francisco?

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to San Francisco from Iowa according to our data. American Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 5 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to San Francisco?

Flight times from Iowa to San Francisco vary, but if you’re flying out of Sioux City and flying into San Francisco (one of the most popular routes), then the duration is 5h 53m on average. Another popular route from Iowa to San Francisco is flying from Des Moines to San Francisco, which will take roughly 6h 07m. Keep in mind that layovers or delays could extend your travel time.

How many flights depart from Iowa to San Francisco on average per week?

As of September 2026, 3 flights take off from Iowa and land in San Francisco each week. The most common flight departure day for this route is Mon, with 33% of weekly flights taking off on this day.

When did momondo last update prices for flights from Iowa to San Francisco Airport?

Prices for flights from Iowa to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Iowa to San Francisco Airport?

The number of operators available for flights from Iowa to San Francisco Airport is 5 as of September 2026.

How old do you have to be to fly from Iowa to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$93 Cheap Flights from Iowa to San Francisco in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Iowa to San Francisco

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:51 pm - 12:20 amOMA Omaha Eppley Airfield-SFO San Francisco

5h 29m1 stop Denver Intl

12:20 pm - 7:27 pmSFO San Francisco-OMA Omaha Eppley Airfield

5h 07m1 stop Denver Intl

$205Frontier

Sat, Oct 31 - Wed, Nov 4

9:31 pm - 6:24 pmDSM Des Moines-SFO San Francisco

22h 53m1 stop Las Vegas Harry Reid Intl

11:17 am - 1:52 pmSFO San Francisco-DSM Des Moines

24h 35m1 stop Las Vegas Harry Reid Intl

$208Multiple Airlines

Mon, Sep 28 - Tue, Oct 6

8:22 pm - 12:15 amOMA Omaha Eppley Airfield-SFO San Francisco

5h 53m1 stop Denver Intl

12:00 pm - 8:06 pmSFO San Francisco-OMA Omaha Eppley Airfield

6h 06m1 stop Denver Intl

$208Frontier

Wed, Oct 14 - Sat, Oct 17

10:23 pm - 8:13 amOMA Omaha Eppley Airfield-SFO San Francisco

11h 50m1 stop Las Vegas Harry Reid Intl

12:00 pm - 8:06 pmSFO San Francisco-OMA Omaha Eppley Airfield

6h 06m1 stop Denver Intl

$217Multiple Airlines

Mon, Oct 12 - Sat, Oct 17

7:51 pm - 11:58 pmDSM Des Moines-SFO San Francisco

6h 07m1 stop Minneapolis St Paul

11:30 pm - 10:42 amSFO San Francisco-DSM Des Moines

9h 12m1 stop Atlanta Hartsfield-Jackson

$337Delta

Thu, Oct 15 - Mon, Oct 19

12:25 pm - 6:21 pmDSM Des Moines-SFO San Francisco

7h 56m1 stop Detroit Metropolitan Wayne County

10:25 pm - 10:42 amSFO San Francisco-DSM Des Moines

10h 17m1 stop Atlanta Hartsfield-Jackson

$337Delta

Sat, Oct 17 - Mon, Oct 19

5:15 pm - 10:43 pmDSM Des Moines-SFO San Francisco

7h 28m1 stop Denver Intl

5:00 am - 2:20 pmSFO San Francisco-DSM Des Moines

7h 20m1 stop Houston George Bush Intcntl

$337United Airlines

Tue, Dec 1 - Sat, Dec 5

4:12 pm - 11:57 pmDSM Des Moines-SFO San Francisco

9h 45m1 stop Dallas/Fort Worth

11:36 pm - 8:56 amSFO San Francisco-DSM Des Moines

7h 20m1 stop Chicago O'Hare Intl

$337American Airlines

Sat, Oct 10 - Mon, Oct 12

7:42 pm - 12:44 amDSM Des Moines-SFO San Francisco

7h 02m1 stop Dallas/Fort Worth

9:27 am - 6:55 pmSFO San Francisco-DSM Des Moines

7h 28m1 stop Los Angeles

$337American Airlines

Thu, Oct 15 - Mon, Oct 26

7:30 am - 10:01 amOMA Omaha Eppley Airfield-SFO San Francisco

4h 31mnonstop

4:25 pm - 9:59 pmSFO San Francisco-OMA Omaha Eppley Airfield

3h 34mnonstop

$339United Airlines

Thu, Jan 14 - Mon, Jan 18

Cheap last minute flights

Enter your travel dates to find the best prices.

9:27 pm - 8:14 amOMA Omaha Eppley Airfield-SFO San Francisco

12h 47m1 stop Las Vegas Harry Reid Intl

7:25 pm - 7:27 pmSFO San Francisco-OMA Omaha Eppley Airfield

22h 02m2 stops Los Angeles Denver Intl

$258Multiple Airlines

Mon, Sep 14 - Tue, Oct 13

9:31 pm - 8:14 amDSM Des Moines-SFO San Francisco

12h 43m1 stop Las Vegas Harry Reid Intl

3:15 pm - 9:06 pmSFO San Francisco-DSM Des Moines

27h 51m1 stop Las Vegas Harry Reid Intl

$304Multiple Airlines

Mon, Sep 14 - Wed, Sep 23

7:29 pm - 10:47 amOMA Omaha Eppley Airfield-SFO San Francisco

17h 18m1 stop Denver Intl

6:04 am - 6:34 pmSFO San Francisco-OMA Omaha Eppley Airfield

10h 30m1 stop Denver Intl

$330Frontier

Fri, Sep 11 - Mon, Sep 21

7:29 pm - 12:14 amOMA Omaha Eppley Airfield-SFO San Francisco

6h 45m1 stop Denver Intl

6:04 am - 6:34 pmSFO San Francisco-OMA Omaha Eppley Airfield

10h 30m1 stop Denver Intl

$350Frontier

Sat, Sep 12 - Sat, Sep 19

3:35 pm - 5:19 pmOMA Omaha Eppley Airfield-SFO San Francisco

3h 44mnonstop

8:53 am - 2:20 pmSFO San Francisco-OMA Omaha Eppley Airfield

3h 27mnonstop

$474United Airlines

Sun, Sep 13 - Mon, Sep 21

4:53 pm - 12:20 amOMA Omaha Eppley Airfield-SFO San Francisco

9h 27m1 stop Dallas/Fort Worth

5:50 am - 2:41 pmSFO San Francisco-OMA Omaha Eppley Airfield

6h 51m1 stop Phoenix Sky Harbor Intl

$474American Airlines

Sun, Sep 13 - Mon, Sep 21

4:53 pm - 10:30 pmOMA Omaha Eppley Airfield-SFO San Francisco

7h 37m1 stop Dallas/Fort Worth

1:27 pm - 11:58 pmSFO San Francisco-OMA Omaha Eppley Airfield

8h 31m1 stop Los Angeles

$474American Airlines

Sun, Sep 13 - Sun, Sep 20

4:30 pm - 9:40 pmOMA Omaha Eppley Airfield-SFO San Francisco

7h 10m1 stop Phoenix Sky Harbor Intl

11:15 am - 9:05 pmSFO San Francisco-OMA Omaha Eppley Airfield

7h 50m2 stops San Diego Las Vegas Harry Reid Intl

$479Southwest

Tue, Sep 15 - Tue, Sep 22

1:55 pm - 7:38 pmOMA Omaha Eppley Airfield-SFO San Francisco

7h 43m1 stop Denver Intl

8:53 am - 2:20 pmSFO San Francisco-OMA Omaha Eppley Airfield

3h 27mnonstop

$484United Airlines

Sun, Sep 13 - Mon, Sep 21

2:30 pm - 9:20 pmOMA Omaha Eppley Airfield-SFO San Francisco

8h 50m2 stops Denver Intl Las Vegas Harry Reid Intl

10:40 am - 8:55 pmSFO San Francisco-OMA Omaha Eppley Airfield

8h 15m2 stops Phoenix Sky Harbor Intl Denver Intl

$484Southwest

Tue, Sep 15 - Tue, Sep 22

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Frontier flights from Iowa to San Francisco

Our best Frontier deals on Iowa to San Francisco flight tickets

Frontier

Oct 14

OMA8:22 pmOmaha Eppley Airfield

23h 56m

1 stop

SFO6:18 pmSan Francisco

Oct 17

SFO6:00 amSan Francisco

12h 06m

1 stop

OMA8:06 pmOmaha Eppley Airfield

$205

Frontier

Oct 14

OMA8:22 pmOmaha Eppley Airfield

5h 53m

1 stop

SFO12:15 amSan Francisco

Oct 17

SFO12:00 pmSan Francisco

6h 06m

1 stop

OMA8:06 pmOmaha Eppley Airfield

$208

Frontier

Oct 14

OMA8:22 pmOmaha Eppley Airfield

15h 32m

2 stops

SFO9:54 amSan Francisco

Oct 17

SFO12:00 pmSan Francisco

6h 06m

1 stop

OMA8:06 pmOmaha Eppley Airfield

$214

Delta flights from Iowa to San Francisco

Our best Delta deals on Iowa to San Francisco flight tickets

Delta

Oct 15

DSM7:51 pmDes Moines

6h 07m

1 stop

SFO11:58 pmSan Francisco

Oct 19

SFO11:30 pmSan Francisco

9h 12m

1 stop

DSM10:42 amDes Moines

$337

Delta

Jan 6

MLI11:00 amMoline Quad-City

8h 11m

1 stop

SFO5:11 pmSan Francisco

Jan 16

SFO6:00 amSan Francisco

8h 22m

1 stop

MLI4:22 pmMoline Quad-City

$361

Delta

Oct 16

MLI5:04 pmMoline Quad-City

8h 52m

1 stop

SFO11:56 pmSan Francisco

Oct 24

SFO11:30 pmSan Francisco

8h 48m

1 stop

MLI10:18 amMoline Quad-City

$370

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OmahaSan Francisco

OMA Omaha Eppley Airfield - SFO San Francisco

OMASFO

Omaha Eppley Airfield

Sat 10/31

8:51 pm-12:20 am

1 stop5h 29m

San Francisco

Wed 11/4

12:20 pm-7:27 pm

1 stop5h 07m

$205

Des MoinesSan Francisco

DSM Des Moines - SFO San Francisco

DSMSFO

Des Moines

Mon 9/28

9:31 pm-6:24 pm

1 stop22h 53m

San Francisco

Tue 10/6

11:17 am-1:52 pm

1 stop24h 35m

$208

OmahaSan Francisco

OMA Omaha Eppley Airfield - SFO San Francisco

OMASFO

Omaha Eppley Airfield

Wed 10/14

8:22 pm-12:15 am

1 stop5h 53m

San Francisco

Sat 10/17

12:00 pm-8:06 pm

1 stop6h 06m

$208

OmahaSan Francisco

OMA Omaha Eppley Airfield - SFO San Francisco

OMASFO

Omaha Eppley Airfield

Mon 10/12

10:23 pm-8:13 am

1 stop11h 50m

San Francisco

Sat 10/17

12:00 pm-8:06 pm

1 stop6h 06m

$217

Des MoinesSan Francisco

DSM Des Moines - SFO San Francisco

DSMSFO

Des Moines

Thu 10/15

7:51 pm-11:58 pm

1 stop6h 07m

San Francisco

Mon 10/19

11:30 pm-10:42 am

1 stop9h 12m

$337

Des MoinesSan Francisco

DSM Des Moines - SFO San Francisco

DSMSFO

Des Moines

Sat 10/17

12:25 pm-6:21 pm

1 stop7h 56m

San Francisco

Mon 10/19

10:25 pm-10:42 am

1 stop10h 17m

$337

Des MoinesSan Francisco

DSM Des Moines - SFO San Francisco

DSMSFO

Des Moines

Tue 12/1

5:15 pm-10:43 pm

1 stop7h 28m

San Francisco

Sat 12/5

5:00 am-2:20 pm

1 stop7h 20m

$337

Des MoinesSan Francisco

DSM Des Moines - SFO San Francisco

DSMSFO

Des Moines

Sat 10/10

4:12 pm-11:57 pm

1 stop9h 45m

San Francisco

Mon 10/12

11:36 pm-8:56 am

1 stop7h 20m

$337

Des MoinesSan Francisco

DSM Des Moines - SFO San Francisco

DSMSFO

Des Moines

Thu 10/15

7:42 pm-12:44 am

1 stop7h 02m

San Francisco

Mon 10/26

9:27 am-6:55 pm

1 stop7h 28m

$337

Quickest round-trip

OmahaSan Francisco

OMA Omaha Eppley Airfield - SFO San Francisco

OMASFO

Omaha Eppley Airfield

Thu 1/14

7:30 am-10:01 am

Nonstop4h 31m

San Francisco

Mon 1/18

4:25 pm-9:59 pm

Nonstop3h 34m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of September, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $398.

How far in advance should I book a flight from Iowa to San Francisco?

You are more likely to see cheaper flights to San Francisco from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $458 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Iowa for as low as $367 on momondo.

Cheap Iowa to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to San Francisco

Best Price Found	$93
Fastest flight time	3h 44m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Iowa in the past 72 hours is $93. The best round-trip flight deal from Iowa to San Francisco found on momondo in the last 72 hours is $205.

The fastest flight from Iowa to San Francisco takes 3h 44m

Direct flights go from Iowa to San Francisco every day.

There is 1 airport in San Francisco. From Iowa there are direct flights to San Francisco (SFO).

Search flight deals

Frequently asked questions about flying from Iowa to San Francisco

When did momondo last update prices for flights from Iowa to San Francisco Airport?
Prices for flights from Iowa to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Iowa to San Francisco Airport?
The number of operators available for flights from Iowa to San Francisco Airport is 5 as of September 2026.
How old do you have to be to fly from Iowa to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to San Francisco

Compare and see reviews for airlines that fly from Iowa to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $120	Free Cancellation	Rating 5.6 2,610 reviews	Search Frontier flights
United Airlines	PriceFrom $253	Free Cancellation	Rating 7.4 10,190 reviews	Search United Airlines flights
Delta	PriceFrom $286	Free Cancellation	Rating 7.8 8,554 reviews	Search Delta flights
American Airlines	PriceFrom $309	Free Cancellation	Rating 7.1 12,045 reviews	Search American Airlines flights
Southwest	PriceFrom $371	Free Cancellation	Rating 8.0 4,195 reviews	Search Southwest flights

Santa Cruz

Carmel-by-the-Sea

Modesto

South San Francisco

Bodega Bay

Hayward

Fremont

Berkeley

Walnut Creek

Santa Clara

Sunnyvale

Vallejo

Salinas

Roseville

Half Moon Bay

Sonoma

Daly City

Milpitas

Marina

Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to San Francisco with flexible booking policies on momondo?

All flight searches from Iowa to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to San Francisco?

momondo helps you find the best flight between Iowa and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Iowa to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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Cheap flights from Iowa to San Francisco from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to San Francisco departing on 9/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Iowa to San Francisco

Our best Frontier deals on Iowa to San Francisco flight tickets

Delta flights from Iowa to San Francisco

Our best Delta deals on Iowa to San Francisco flight tickets

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How to get the cheapest flight ticket from Iowa to San Francisco

What is the cheapest month to fly to San Francisco?

How far in advance should I book a flight from Iowa to San Francisco?

What is the cheapest airline that flies from Iowa to San Francisco?

What airlines fly to San Francisco?

How many flights depart from Iowa to San Francisco on average per week?

How long does it take to fly to San Francisco?

Cheap Iowa to San Francisco flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

Frequently asked questions about flying from Iowa to San Francisco

Best airlines flying from Iowa to San Francisco

Compare and see reviews for airlines that fly from Iowa to San Francisco with momondo

Traveling to a place near San Francisco?

Why use momondo?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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