Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Iowa to San Francisco from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to San Francisco departing on 10/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Iowa to San Francisco

Cheap round-trip flights

Frontier Logo
2:25 pm - 12:16 amDSM-SFO
11h 51m1 stop
Frontier Logo
6:29 am - 1:40 pmSFO-DSM
5h 11m1 stop
$149Frontier
Find Deal
Fri, Oct 3 - Mon, Oct 6
Frontier Logo
8:16 pm - 12:16 amCID-SFO
6h 00m1 stop
Frontier Logo
10:45 am - 7:31 pmSFO-CID
6h 46m1 stop
$150Frontier
Find Deal
Fri, Sep 5 - Mon, Sep 8
Southwest Logo
4:00 pm - 9:15 pmOMA-SFO
7h 15m1 stop
Southwest Logo
8:35 am - 3:35 pmSFO-OMA
5h 00m1 stop
$234Southwest
Find Deal
Thu, Sep 4 - Wed, Sep 10
Southwest Logo
4:00 pm - 11:20 pmOMA-SFO
9h 20m2 stops
Southwest Logo
1:45 pm - 10:00 pmSFO-OMA
6h 15m1 stop
$239Southwest
Find Deal
Thu, Sep 4 - Wed, Sep 10
United Airlines Logo
7:35 am - 9:25 amOMA-SFO
3h 50mnonstop
United Airlines Logo
4:25 pm - 9:56 pmSFO-OMA
3h 31mnonstop
$249United Airlines
Find Deal
Wed, Feb 4 - Wed, Feb 25
Logo
3:30 pm - 9:21 pmDSM-SFO
7h 51m1 stop
Logo
10:37 pm - 10:29 pmSFO-DSM
21h 52m1 stop
$250
Find Deal
Mon, Sep 15 - Thu, Sep 18
United Airlines Logo
6:00 am - 9:44 amOMA-SFO
5h 44m1 stop
United Airlines Logo
4:55 pm - 10:13 pmSFO-OMA
3h 18mnonstop
$259United Airlines
Find Deal
Sat, Sep 13 - Tue, Sep 16
Alaska Airlines Logo
3:14 pm - 9:20 pmOMA-SFO
8h 06m1 stop
Alaska Airlines Logo
6:00 am - 2:18 pmSFO-OMA
6h 18m1 stop
$269Alaska Airlines
Find Deal
Sat, Sep 20 - Sun, Sep 21
Logo
10:17 pm - 6:04 pmCID-SFO
21h 47m1 stop
Logo
5:45 am - 8:11 pmSFO-CID
12h 26m1 stop
$270
Find Deal
Fri, Oct 24 - Mon, Oct 27
Alaska Airlines Logo
3:14 pm - 9:20 pmOMA-SFO
8h 06m1 stop
Alaska Airlines Logo
6:00 am - 11:59 pmSFO-OMA
15h 59m2 stops
$279Alaska Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13

Frontier flights from Iowa to San Francisco

Our best Frontier deals on Iowa to San Francisco flight tickets
Frontier
Oct 3
DSM2:25 pmDes Moines
11h 51m
1 stop
SFO12:16 amSan Francisco
Oct 6
SFO6:29 amSan Francisco
5h 11m
1 stop
DSM1:40 pmDes Moines
$149
Find similar
Frontier
Sep 5
CID8:16 pmCedar Rapids
6h 00m
1 stop
SFO12:16 amSan Francisco
Sep 8
SFO10:45 amSan Francisco
6h 46m
1 stop
CID7:31 pmCedar Rapids
$150
Find similar
Frontier
Nov 10
DSM8:44 pmDes Moines
5h 30m
1 stop
SFO12:14 amSan Francisco
Nov 13
SFO10:43 amSan Francisco
7h 16m
1 stop
DSM7:59 pmDes Moines
$166
Find similar

American Airlines flights from Iowa to San Francisco

Our best American Airlines deals on Iowa to San Francisco flight tickets
American Airlines
Sep 27
OMA3:46 pmOmaha Eppley Airfield
7h 19m
1 stop
SFO9:05 pmSan Francisco
Oct 4
SFO6:45 amSan Francisco
8h 35m
2 stops
OMA5:20 pmOmaha Eppley Airfield
$274
Find similar
American Airlines
Sep 24
DSM5:10 amDes Moines
7h 17m
1 stop
SFO10:27 amSan Francisco
Oct 6
SFO12:50 amSan Francisco
6h 10m
1 stop
DSM9:00 amDes Moines
$283
Find similar
American Airlines
Sep 24
DSM5:10 amDes Moines
9h 58m
2 stops
SFO1:08 pmSan Francisco
Oct 6
SFO12:50 amSan Francisco
6h 10m
1 stop
DSM9:00 amDes Moines
$288
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Iowa to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Fri 10/3

2:25 pm-12:16 am

1 stop11h 51m

San Francisco

Mon 10/6

6:29 am-1:40 pm

1 stop5h 11m

$149

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

Fri 9/5

8:16 pm-12:16 am

1 stop6h 00m

San Francisco

Mon 9/8

10:45 am-7:31 pm

1 stop6h 46m

$150

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Thu 9/4

4:00 pm-9:15 pm

1 stop7h 15m

San Francisco

Wed 9/10

8:35 am-3:35 pm

1 stop5h 00m

$234

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Thu 9/4

4:00 pm-11:20 pm

2 stops9h 20m

San Francisco

Wed 9/10

1:45 pm-10:00 pm

1 stop6h 15m

$239

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Wed 2/4

7:35 am-9:25 am

Nonstop3h 50m

San Francisco

Wed 2/25

4:25 pm-9:56 pm

Nonstop3h 31m

$249

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

Mon 9/15

3:30 pm-9:21 pm

1 stop7h 51m

San Francisco

Thu 9/18

10:37 pm-10:29 pm

1 stop21h 52m

$250

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Sat 9/13

6:00 am-9:44 am

1 stop5h 44m

San Francisco

Tue 9/16

4:55 pm-10:13 pm

Nonstop3h 18m

$259

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Sat 9/20

3:14 pm-9:20 pm

1 stop8h 06m

San Francisco

Sun 9/21

6:00 am-2:18 pm

1 stop6h 18m

$269

Cedar RapidsSan Francisco

CID - SFO

CIDSFO

Cedar Rapids

Fri 10/24

10:17 pm-6:04 pm

1 stop21h 47m

San Francisco

Mon 10/27

5:45 am-8:11 pm

1 stop12h 26m

$270

OmahaSan Francisco

OMA - SFO

OMASFO

Omaha Eppley Airfield

Tue 9/9

3:14 pm-9:20 pm

1 stop8h 06m

San Francisco

Sat 9/13

6:00 am-11:59 pm

2 stops15h 59m

$279

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Iowa to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $414.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Iowa to San Francisco is on a Friday when prices can be found for as low as $450. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $541.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Iowa to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $371. Flights at noon are often more expensive with an average ticket price of $471.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Iowa when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $440 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Iowa for as low as $381 on momondo.

Cheap Iowa to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to San Francisco

Best Price Found

$76

Fastest flight time

3h 42m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Iowa in the past 72 hours is $76. The best round-trip flight deal from Iowa to San Francisco found on momondo in the last 72 hours is $149.
The fastest flight from Iowa to San Francisco takes 3h 42m
Direct flights go from Iowa to San Francisco every day.
There is 1 airport near San Francisco: San Francisco (SFO)
Search flight deals

  • When did momondo last update prices for flights from Iowa to San Francisco Airport?

    Prices for flights from Iowa to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to San Francisco Airport?

  • How old do you have to be to fly from Iowa to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to San Francisco

Compare and see reviews for airlines that fly from Iowa to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $108Free CancellationRating
5.8
3,219 reviews
Search Frontier flights
DeltaPriceFrom $265Free CancellationRating
8.0
7,980 reviews
Search Delta flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
8,916 reviews
Search United Airlines flights
American AirlinesPriceFrom $288Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $350Free CancellationRating
8.0
4,244 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Calistoga
Sonoma
Hayward
Bodega Bay
Roseville
Santa Clara
Big Sur
Daly City
Fremont
Berkeley
Walnut Creek
Half Moon Bay
South San Francisco
Vallejo
Redwood City
Sunnyvale
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to San Francisco with flexible booking policies on momondo?

All flight searches from Iowa to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Iowa to San Francisco?

momondo helps you find the best flight between Iowa and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Iowa to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Iowa to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 8/19
Tue 8/26
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States