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Cheap flights from Indianapolis to San Francisco from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 12/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
5:30 am - 9:50 pmIND-SFO
19h 20m2 stops
Multiple Airlines Logo
11:33 pm - 6:50 pmSFO-IND
16h 17m1 stop
$272Multiple Airlines
Find Deal
Sat, Dec 6 - Sun, Dec 7
United Airlines Logo
9:58 am - 12:05 pmIND-SFO
5h 07mnonstop
United Airlines Logo
12:25 pm - 10:14 pmSFO-IND
6h 49m1 stop
$275United Airlines
Find Deal
Thu, Jan 22 - Mon, Jan 26
Multiple Airlines Logo
5:30 am - 9:50 pmIND-SFO
19h 20m2 stops
Multiple Airlines Logo
6:00 am - 4:34 pmSFO-IND
7h 34m1 stop
$278Multiple Airlines
Find Deal
Sat, Dec 6 - Mon, Dec 8
Frontier Logo
8:39 pm - 12:14 amIND-SFO
6h 35m1 stop
Frontier Logo
6:34 am - 6:44 pmSFO-IND
9h 10m1 stop
$282Frontier
Find Deal
Thu, Nov 13 - Mon, Nov 17
Frontier Logo
12:17 pm - 9:11 pmIND-SFO
11h 54m1 stop
Frontier Logo
6:34 am - 6:44 pmSFO-IND
9h 10m1 stop
$287Frontier
Find Deal
Fri, Nov 14 - Mon, Nov 17
Delta Logo
12:52 pm - 6:04 pmIND-SFO
8h 12m1 stop
Delta Logo
12:30 am - 12:07 pmSFO-IND
8h 37m1 stop
$289Delta
Find Deal
Sat, Dec 6 - Mon, Dec 8
Delta Logo
6:13 am - 1:43 pmIND-SFO
10h 30m2 stops
Delta Logo
10:30 am - 10:49 pmSFO-IND
9h 19m2 stops
$290Delta
Find Deal
Thu, Jan 22 - Mon, Jan 26
Southwest Logo
5:50 am - 9:30 amIND-SFO
6h 40m1 stop
Southwest Logo
11:40 am - 11:45 pmSFO-IND
9h 05m2 stops
$294Southwest
Find Deal
Sat, Dec 6 - Tue, Dec 9
Southwest Logo
6:00 am - 12:10 pmIND-SFO
9h 10m2 stops
Southwest Logo
9:50 am - 9:05 pmSFO-IND
8h 15m1 stop
$306Southwest
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Thu, Dec 18 - Thu, Jan 8
American Airlines Logo
5:15 pm - 10:58 pmIND-SFO
8h 43m1 stop
American Airlines Logo
11:59 pm - 10:36 amSFO-IND
7h 37m1 stop
$348American Airlines
Find Deal
Mon, Dec 22 - Sat, Dec 27

Frontier flights from Indianapolis to San Francisco

Our best Frontier deals on Indianapolis to San Francisco flight tickets
Frontier
Nov 13
IND8:39 pmIndianapolis
6h 35m
1 stop
SFO12:14 amSan Francisco
Nov 17
SFO6:34 amSan Francisco
9h 10m
1 stop
IND6:44 pmIndianapolis
$282
Find similar
Frontier
Nov 14
IND12:17 pmIndianapolis
11h 54m
1 stop
SFO9:11 pmSan Francisco
Nov 17
SFO6:34 amSan Francisco
9h 10m
1 stop
IND6:44 pmIndianapolis
$287
Find similar
Frontier
Nov 13
IND8:39 pmIndianapolis
21h 01m
1 stop
SFO2:40 pmSan Francisco
Nov 16
SFO10:23 pmSan Francisco
9h 59m
1 stop
IND11:22 amIndianapolis
$298
Find similar

United Airlines flights from Indianapolis to San Francisco

Our best United Airlines deals on Indianapolis to San Francisco flight tickets
United Airlines
Jan 22
IND9:58 amIndianapolis
5h 07m
SFO12:05 pmSan Francisco
Jan 26
SFO12:25 pmSan Francisco
6h 49m
1 stop
IND10:14 pmIndianapolis
$275
Find similar
United Airlines
Dec 5
IND7:28 amIndianapolis
5h 03m
SFO9:31 amSan Francisco
Dec 6
SFO12:43 amSan Francisco
7h 10m
1 stop
IND10:53 amIndianapolis
$279
Find similar
United Airlines
Feb 3
IND11:40 amIndianapolis
8h 10m
1 stop
SFO4:50 pmSan Francisco
Feb 7
SFO12:25 pmSan Francisco
6h 49m
1 stop
IND10:14 pmIndianapolis
$284
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sat 12/6

5:30 am-9:50 pm

2 stops19h 20m

San Francisco

Sun 12/7

11:33 pm-6:50 pm

1 stop16h 17m

$272

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

9:58 am-12:05 pm

Nonstop5h 07m

San Francisco

Mon 1/26

12:25 pm-10:14 pm

1 stop6h 49m

$275

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sat 12/6

5:30 am-9:50 pm

2 stops19h 20m

San Francisco

Mon 12/8

6:00 am-4:34 pm

1 stop7h 34m

$278

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 11/13

8:39 pm-12:14 am

1 stop6h 35m

San Francisco

Mon 11/17

6:34 am-6:44 pm

1 stop9h 10m

$282

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 11/14

12:17 pm-9:11 pm

1 stop11h 54m

San Francisco

Mon 11/17

6:34 am-6:44 pm

1 stop9h 10m

$287

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sat 12/6

12:52 pm-6:04 pm

1 stop8h 12m

San Francisco

Mon 12/8

12:30 am-12:07 pm

1 stop8h 37m

$289

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

6:13 am-1:43 pm

2 stops10h 30m

San Francisco

Mon 1/26

10:30 am-10:49 pm

2 stops9h 19m

$290

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sat 12/6

5:50 am-9:30 am

1 stop6h 40m

San Francisco

Tue 12/9

11:40 am-11:45 pm

2 stops9h 05m

$294

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 12/18

6:00 am-12:10 pm

2 stops9h 10m

San Francisco

Thu 1/8

9:50 am-9:05 pm

1 stop8h 15m

$306

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 12/22

5:15 pm-10:58 pm

1 stop8h 43m

San Francisco

Sat 12/27

11:59 pm-10:36 am

1 stop7h 37m

$348

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $337.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $474. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $759.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $519. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $369 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $323 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of November 2025, prices for Indianapolis to San Francisco flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

$203

Fastest flight time

4h 59m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $203. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $322.
The fastest flight from Indianapolis to San Francisco takes 4h 59m
Direct flights go from Indianapolis to San Francisco every day.
There is 1 airport near San Francisco: San Francisco (SFO)
Search flight deals

  • How far is Indianapolis to San Francisco by plane?

    There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 5h 03m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

    Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Francisco?

  • What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $130Free CancellationRating
5.8
3,117 reviews
Search Frontier flights
Sun Country AirPriceFrom $149Free CancellationRating
6.9
334 reviews
Search Sun Country Air flights
DeltaPriceFrom $220Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $239Free CancellationRating
7.2
11,035 reviews
Search American Airlines flights
United AirlinesPriceFrom $269Free CancellationRating
7.4
8,996 reviews
Search United Airlines flights
SouthwestPriceFrom $284Free CancellationRating
8.0
4,238 reviews
Search Southwest flights

  • Southwest Flights From Indianapolis to San Francisco

    Southwest flight deals from Indianapolis to San Francisco start from $284 round-trip. Over the 3 Southwest flights for this route in a normal week, average airfare is usually $419 round-trip - but some users have found much cheaper deals with momondo.

  • United Airlines Flights From Indianapolis to San Francisco

    United Airlines is also a popular choice for this route. United Airlines flight deals for Indianapolis to San Francisco start from as low as $269 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $409. United Airlines operates 8 flights to San Francisco from Indianapolis in an average week. Users have rated it 7.4/10 across 8,996 reviews.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Calistoga
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Vallejo
Walnut Creek
Half Moon Bay
Salinas
Turlock
Livermore
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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