Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 22% of momondo users choosing 1-stop flights on this route connected there.

How many flights depart from Indianapolis to San Francisco on average per week?

As of September 2025, there are 21 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Delta, Frontier, and Hawaiian Airlines are the most popular carriers operating from Indianapolis to San Francisco

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

What airlines fly to San Francisco?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to San Francisco from Indianapolis according to our data. United Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 9 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 3 per day as of September 2025. The most frequent departure time is 6:00AM, with 100% of daily flights leaving at noon.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Dallas (DFW) has the shortest average layover time for this route: 1h 00m.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Detroit (DTW) offer the lowest average round-trip price of $313.

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

There are 6 operators available for flights from Indianapolis Airport to San Francisco Airport as of September 2025.

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$128 Cheap Flights from Indianapolis to San Francisco in 2025/26

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Find the cheapest flights from Indianapolis to San Francisco

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

12:06 pm - 11:02 pmIND-SFO

13h 56m2 stops

11:57 pm - 5:10 pmSFO-IND

14h 13m2 stops

$273Frontier

Find Deal

vie., oct. 3 - dom., oct. 5

6:45 am - 12:10 pmIND-SFO

8h 25m1 stop

10:54 pm - 6:14 amSFO-IND

4h 20mnonstop

$275United Airlines

Find Deal

jue., oct. 30 - dom., nov. 2

8:54 pm - 1:17 pmIND-SFO

19h 23m1 stop

5:45 am - 6:57 pmSFO-IND

10h 12m1 stop

$280Multiple Airlines

Find Deal

dom., sep. 28 - jue., oct. 9

8:08 pm - 12:05 amIND-SFO

6h 57m1 stop

10:57 pm - 11:14 amSFO-IND

9h 17m1 stop

$288Delta

Find Deal

jue., oct. 16 - mar., oct. 21

11:56 am - 5:20 pmIND-SFO

8h 24m1 stop

12:27 am - 10:50 amSFO-IND

7h 23m1 stop

$289American Airlines

Find Deal

vie., dic. 12 - vie., ene. 9

5:45 am - 9:21 pmIND-SFO

18h 36m2 stops

11:00 pm - 11:11 amSFO-IND

9h 11m1 stop

$293Multiple Airlines

Find Deal

mar., sep. 30 - dom., oct. 5

12:18 pm - 6:00 pmIND-SFO

8h 42m1 stop

2:00 pm - 12:22 amSFO-IND

7h 22m1 stop

$298Delta

Find Deal

mié., oct. 1 - sáb., oct. 11

9:15 pm - 12:30 amIND-SFO

6h 15m1 stop

9:30 pm - 10:30 amSFO-IND

10h 00m1 stop

$305Southwest

Find Deal

sáb., dic. 20 - sáb., ene. 10

7:50 am - 12:21 pmIND-SFO

7h 31m1 stop

12:27 am - 10:50 amSFO-IND

7h 23m1 stop

$314American Airlines

Find Deal

vie., dic. 19 - sáb., ene. 10

5:00 pm - 10:30 pmIND-SFO

8h 30m2 stops

5:30 am - 2:35 pmSFO-IND

6h 05m1 stop

$315Southwest

Find Deal

mié., dic. 31 - mar., ene. 6

Frontier flights from Indianapolis to San Francisco

Our best Frontier deals on Indianapolis to San Francisco flight tickets

Frontier

Oct 3

IND12:06 pmIndianapolis

13h 56m

2 stops

SFO11:02 pmSan Francisco

Oct 5

SFO11:57 pmSan Francisco

14h 13m

2 stops

IND5:10 pmIndianapolis

$273

Find similar

Frontier

Sep 25

IND8:54 pmIndianapolis

6h 22m

1 stop

SFO12:16 amSan Francisco

Sep 28

SFO6:29 amSan Francisco

10h 35m

1 stop

IND8:04 pmIndianapolis

$275

Find similar

Frontier

Oct 13

IND8:51 pmIndianapolis

28h 36m

1 stop

SFO10:27 pmSan Francisco

Oct 19

SFO8:21 pmSan Francisco

20h 45m

1 stop

IND8:06 pmIndianapolis

$277

Find similar

United Airlines flights from Indianapolis to San Francisco

Our best United Airlines deals on Indianapolis to San Francisco flight tickets

United Airlines

Oct 30

IND6:45 amIndianapolis

8h 25m

1 stop

SFO12:10 pmSan Francisco

Nov 2

SFO10:54 pmSan Francisco

4h 20m

IND6:14 amIndianapolis

$275

Find similar

United Airlines

Oct 16

IND6:00 amIndianapolis

4h 50m

SFO7:50 amSan Francisco

Oct 22

SFO12:43 amSan Francisco

7h 14m

1 stop

IND10:57 amIndianapolis

$279

Find similar

United Airlines

Oct 1

IND6:00 amIndianapolis

4h 50m

SFO7:50 amSan Francisco

Oct 8

SFO1:10 pmSan Francisco

4h 24m

IND8:34 pmIndianapolis

$294

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momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

vie. 10/3

12:06 pm-11:02 pm

2 stops13h 56m

San Francisco

dom. 10/5

11:57 pm-5:10 pm

2 stops14h 13m

$273

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

jue. 10/30

6:45 am-12:10 pm

1 stop8h 25m

San Francisco

dom. 11/2

10:54 pm-6:14 am

Nonstop4h 20m

$275

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

dom. 9/28

8:54 pm-1:17 pm

1 stop19h 23m

San Francisco

jue. 10/9

5:45 am-6:57 pm

1 stop10h 12m

$280

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

jue. 10/16

8:08 pm-12:05 am

1 stop6h 57m

San Francisco

mar. 10/21

10:57 pm-11:14 am

1 stop9h 17m

$288

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

vie. 12/12

11:56 am-5:20 pm

1 stop8h 24m

San Francisco

vie. 1/9

12:27 am-10:50 am

1 stop7h 23m

$289

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mar. 9/30

5:45 am-9:21 pm

2 stops18h 36m

San Francisco

dom. 10/5

11:00 pm-11:11 am

1 stop9h 11m

$293

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mié. 10/1

12:18 pm-6:00 pm

1 stop8h 42m

San Francisco

sáb. 10/11

2:00 pm-12:22 am

1 stop7h 22m

$298

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

sáb. 12/20

9:15 pm-12:30 am

1 stop6h 15m

San Francisco

sáb. 1/10

9:30 pm-10:30 am

1 stop10h 00m

$305

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

vie. 12/19

7:50 am-12:21 pm

1 stop7h 31m

San Francisco

sáb. 1/10

12:27 am-10:50 am

1 stop7h 23m

$314

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mié. 12/31

5:00 pm-10:30 pm

2 stops8h 30m

San Francisco

mar. 1/6

5:30 am-2:35 pm

1 stop6h 05m

$315

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $359.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $479. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $856.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $542. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $373 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $326 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of September 2025, prices for Indianapolis to San Francisco flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found	$278
Fastest flight time	4h 45m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $278. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $384.

The fastest flight from Indianapolis to San Francisco takes 4h 45m

Direct flights go from Indianapolis to San Francisco every day.

There is 1 airport near San Francisco: San Francisco (SFO)

Search flight deals

How far is Indianapolis to San Francisco by plane?
There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 4h 48m.
When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?
Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?
There are 6 operators available for flights from Indianapolis Airport to San Francisco Airport as of September 2025.
How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to San Francisco is Boeing 737-800, representing 49.52% of all bookings. The subsequent popular models are Airbus A319 at 26.43%, Boeing 737 MAX 8 at 13.33%, and Boeing 737 MAX 9 at 1.43%.
What is the most popular airline from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Indianapolis to San Francisco is United Airlines, representing 56% of all bookings. The subsequent popular airlines are Delta at 18%, American Airlines at 13%, and Southwest at 7%.

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $130	Free Cancellation	Rating 5.8 3,174 reviews	Search Frontier flights
Sun Country Air	PriceFrom $192	Free Cancellation	Rating 6.9 330 reviews	Search Sun Country Air flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 7,957 reviews	Search Delta flights
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 8,924 reviews	Search United Airlines flights
Southwest	PriceFrom $288	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights

United Airlines Flights From Indianapolis to San Francisco
United Airlines flight deals from Indianapolis to San Francisco start from $269 round-trip. Over the 7 United Airlines flights for this route in a normal week, average airfare is usually $420 round-trip - but some users have found much cheaper deals with momondo.

Santa Cruz

Carmel-by-the-Sea

Modesto

Sonoma

Calistoga

Bodega Bay

Roseville

Hayward

Big Sur

Santa Clara

Daly City

Fremont

Berkeley

Half Moon Bay

Walnut Creek

Vallejo

Redwood City

Salinas

South San Francisco

Fairfield

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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jue. 10/16

jue. 10/23

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Flights to Orlandofrom $60

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Flights to Washington, D.C.from $49

Flights to Bostonfrom $62

Flights to Atlantafrom $51

Flights to Dallasfrom $68

Flights to Seattlefrom $69

Flights to Denverfrom $63

Cheap flights from Indianapolis to San Francisco from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 10/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Filter for what you want

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Find the cheapest flights from Indianapolis to San Francisco

Cheap round-trip flights

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Cheap last minute flights

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Frontier flights from Indianapolis to San Francisco

Our best Frontier deals on Indianapolis to San Francisco flight tickets

United Airlines flights from Indianapolis to San Francisco

Our best United Airlines deals on Indianapolis to San Francisco flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $359.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $479. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $856.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $542. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of September 2025, prices for Indianapolis to San Francisco flights are approximately 13% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Delta, Frontier, and Hawaiian Airlines are the most popular carriers operating from Indianapolis to San Francisco

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 22% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Detroit (DTW) offer the lowest average round-trip price of $313.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Dallas (DFW) has the shortest average layover time for this route: 1h 00m.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 3 per day as of September 2025. The most frequent departure time is 6:00AM, with 100% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of September 2025, there are 21 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.

When to book flights from Indianapolis to San Francisco

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

How far is Indianapolis to San Francisco by plane?

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

What documentation or ID do you need to fly to San Francisco Airport?

What is the most popular plane model from Indianapolis to San Francisco?

What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

United Airlines Flights From Indianapolis to San Francisco

Traveling to a place near San Francisco?

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

How can momondo help me find flights from Indianapolis to San Francisco?

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States