Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Chicago (ORD) offer the lowest average round-trip price of $482.

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 2 per day as of January 2026. The most frequent departure time is 7:00AM, with 100% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of January 2026, there are 16 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 25% of flights taking off on this day.

What airlines fly to San Francisco?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to San Francisco from Indianapolis according to our data. United Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Las Vegas (LAS) has the shortest average layover time for this route: 1h 20m.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Alaska Airlines, Delta, and Frontier are the most popular carriers operating from Indianapolis to San Francisco

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

There are 5 operators available for flights from Indianapolis Airport to San Francisco Airport as of January 2026.

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$151 Cheap Flights from Indianapolis to San Francisco in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Indianapolis to San Francisco

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:10 am - 2:21 pm

IND

SFO

10h 11m1 stop

10:25 am - 5:50 am

SFO

IND

16h 25m1 stop

$269Alaska Airlines

Thu, Apr 23 - Tue, Apr 28

12:38 pm - 11:41 pm

IND

SFO

38h 03m2 stops

8:23 pm - 4:44 pm

SFO

IND

17h 21m1 stop

$270Multiple Airlines

Fri, Jan 23 - Thu, Jan 29

8:52 pm - 12:28 am

IND

SFO

6h 36m1 stop

6:00 am - 7:38 pm

SFO

IND

10h 38m1 stop

$271Frontier

Thu, Mar 5 - Sun, Mar 8

4:30 pm - 12:28 am

IND

SFO

10h 58m1 stop

7:00 am - 7:36 pm

SFO

IND

33h 36m2 stops

$274Frontier

Thu, Jan 22 - Wed, Jan 28

4:30 pm - 12:28 am

IND

SFO

10h 58m1 stop

7:00 am - 7:36 pm

SFO

IND

33h 36m2 stops

$276Frontier

Thu, Jan 22 - Wed, Jan 28

10:10 am - 12:20 pm

IND

SFO

5h 10mnonstop

11:59 pm - 11:21 am

SFO

IND

8h 22m1 stop

$279United Airlines

Wed, Mar 4 - Sun, Mar 8

7:05 am - 1:43 pm

IND

SFO

9h 38m2 stops

10:30 am - 12:07 am

SFO

IND

10h 37m2 stops

$281Delta

Thu, Jan 22 - Mon, Jan 26

4:30 pm - 12:28 am

IND

SFO

10h 58m1 stop

7:00 am - 11:43 am

SFO

IND

49h 43m2 stops

$283Frontier

Thu, Jan 22 - Tue, Jan 27

7:00 am - 12:55 pm

IND

SFO

8h 55m1 stop

10:30 am - 12:07 am

SFO

IND

10h 37m2 stops

$285Delta

Thu, Jan 22 - Mon, Jan 26

12:21 pm - 11:41 pm

IND

SFO

38h 20m2 stops

8:23 pm - 4:44 pm

SFO

IND

17h 21m1 stop

$288Multiple Airlines

Tue, Jan 20 - Thu, Jan 29

Delta flights from Indianapolis to San Francisco

Our best Delta deals on Indianapolis to San Francisco flight tickets

Delta

Jan 22

IND7:05 amIndianapolis

9h 38m

2 stops

SFO1:43 pmSan Francisco

Jan 26

SFO10:30 amSan Francisco

10h 37m

2 stops

IND12:07 amIndianapolis

$281

Find similar

Delta

Jan 22

IND7:00 amIndianapolis

8h 55m

1 stop

SFO12:55 pmSan Francisco

Jan 26

SFO10:30 amSan Francisco

10h 37m

2 stops

IND12:07 amIndianapolis

$285

Find similar

Delta

Mar 4

IND4:40 pmIndianapolis

10h 07m

1 stop

SFO11:47 pmSan Francisco

Mar 16

SFO10:40 pmSan Francisco

8h 09m

1 stop

IND9:49 amIndianapolis

$289

Find similar

Southwest flights from Indianapolis to San Francisco

Our best Southwest deals on Indianapolis to San Francisco flight tickets

Southwest

Jan 22

IND6:40 amIndianapolis

10h 40m

2 stops

SFO2:20 pmSan Francisco

Jan 28

SFO11:30 amSan Francisco

8h 40m

2 stops

IND11:10 pmIndianapolis

$300

Find similar

Southwest

Mar 4

IND5:50 amIndianapolis

9h 15m

2 stops

SFO12:05 pmSan Francisco

Mar 16

SFO6:50 amSan Francisco

13h 50m

2 stops

IND11:40 pmIndianapolis

$305

Find similar

Southwest

Jan 31

IND12:55 pmIndianapolis

6h 40m

1 stop

SFO4:35 pmSan Francisco

Feb 3

SFO11:30 amSan Francisco

8h 40m

2 stops

IND11:10 pmIndianapolis

$325

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 4/23

7:10 am-2:21 pm

1 stop10h 11m

San Francisco

Tue 4/28

10:25 am-5:50 am

1 stop16h 25m

$269

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 1/23

12:38 pm-11:41 pm

2 stops38h 03m

San Francisco

Thu 1/29

8:23 pm-4:44 pm

1 stop17h 21m

$270

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 3/5

8:52 pm-12:28 am

1 stop6h 36m

San Francisco

Sun 3/8

6:00 am-7:38 pm

1 stop10h 38m

$271

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

4:30 pm-12:28 am

1 stop10h 58m

San Francisco

Wed 1/28

7:00 am-7:36 pm

2 stops33h 36m

$274

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

4:30 pm-12:28 am

1 stop10h 58m

San Francisco

Wed 1/28

7:00 am-7:36 pm

2 stops33h 36m

$276

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 3/4

10:10 am-12:20 pm

Nonstop5h 10m

San Francisco

Sun 3/8

11:59 pm-11:21 am

1 stop8h 22m

$279

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

7:05 am-1:43 pm

2 stops9h 38m

San Francisco

Mon 1/26

10:30 am-12:07 am

2 stops10h 37m

$281

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

4:30 pm-12:28 am

1 stop10h 58m

San Francisco

Tue 1/27

7:00 am-11:43 am

2 stops49h 43m

$283

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/22

7:00 am-12:55 pm

1 stop8h 55m

San Francisco

Mon 1/26

10:30 am-12:07 am

2 stops10h 37m

$285

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Tue 1/20

12:21 pm-11:41 pm

2 stops38h 20m

San Francisco

Thu 1/29

8:23 pm-4:44 pm

1 stop17h 21m

$288

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $336.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $476. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $783.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $530. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $372 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $309 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of January 2026, prices for Indianapolis to San Francisco flights are approximately 24% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found	$363
Fastest flight time	4h 57m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $363. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $422.

The fastest flight from Indianapolis to San Francisco takes 4h 57m

Direct flights go from Indianapolis to San Francisco every day.

There is 1 airport in San Francisco. From Indianapolis there are direct flights to San Francisco (SFO).

Search flight deals

How far is Indianapolis to San Francisco by plane?
There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 4h 57m.
When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?
Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?
There are 5 operators available for flights from Indianapolis Airport to San Francisco Airport as of January 2026.
How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to San Francisco is Airbus A319, representing 29.32% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 26.37%, Boeing 737-800 at 20.25%, and Airbus A320-100/200 at 11.39%.
What is the most popular airline from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Indianapolis to San Francisco is United Airlines, representing 59% of all bookings. The subsequent popular airlines are Delta at 15%, American Airlines at 10%, and Southwest at 9%.

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $130	Free Cancellation	Rating 5.7 3,063 reviews	Search Frontier flights
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 8,024 reviews	Search Delta flights
American Airlines	PriceFrom $238	Free Cancellation	Rating 7.2 11,081 reviews	Search American Airlines flights
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 9,137 reviews	Search United Airlines flights
Southwest	PriceFrom $284	Free Cancellation	Rating 8.0 4,257 reviews	Search Southwest flights

United Airlines Flights From Indianapolis to San Francisco
United Airlines flight deals from Indianapolis to San Francisco start from $269 round-trip. Over the 8 United Airlines flights for this route in a normal week, average airfare is usually $402 round-trip - but some users have found much cheaper deals with momondo.

Santa Cruz

Carmel-by-the-Sea

Modesto

Sonoma

Bodega Bay

Roseville

Hayward

Calistoga

Big Sur

Santa Clara

Berkeley

Walnut Creek

Fremont

Daly City

Half Moon Bay

Vallejo

Livermore

Salinas

Sunnyvale

Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Mon 2/2

Mon 2/9

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Airports servicing California

Popular cities in the United States

Flights to New Yorkfrom $53

Flights to Los Angelesfrom $39

Flights to Miamifrom $49

Flights to Chicagofrom $59

Flights to Orlandofrom $43

Flights to Las Vegasfrom $53

Flights to Washington, D.C.from $58

Flights to Bostonfrom $31

Flights to Atlantafrom $42

Flights to Dallasfrom $57

Flights to Seattlefrom $57

Flights to Denverfrom $53

Cheap flights from Indianapolis to San Francisco from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 2/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Indianapolis to San Francisco

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Delta flights from Indianapolis to San Francisco

Our best Delta deals on Indianapolis to San Francisco flight tickets

Southwest flights from Indianapolis to San Francisco

Our best Southwest deals on Indianapolis to San Francisco flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $336.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $476. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $783.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $530. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of January 2026, prices for Indianapolis to San Francisco flights are approximately 24% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Alaska Airlines, Delta, and Frontier are the most popular carriers operating from Indianapolis to San Francisco

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Chicago (ORD) offer the lowest average round-trip price of $482.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Las Vegas (LAS) has the shortest average layover time for this route: 1h 20m.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 2 per day as of January 2026. The most frequent departure time is 7:00AM, with 100% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of January 2026, there are 16 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 25% of flights taking off on this day.

When to book flights from Indianapolis to San Francisco

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

How far is Indianapolis to San Francisco by plane?

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

What documentation or ID do you need to fly to San Francisco Airport?

What is the most popular plane model from Indianapolis to San Francisco?

What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

United Airlines Flights From Indianapolis to San Francisco

Traveling to a place near San Francisco?

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

How can momondo help me find flights from Indianapolis to San Francisco?

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California