Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Chicago (ORD) offer the lowest average round-trip price of $482.

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Frontier, Southwest, and Delta are the most popular carriers operating from Indianapolis to San Francisco

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Las Vegas (LAS) has the shortest average layover time for this route: 1h 20m.

What airlines fly to San Francisco?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to San Francisco from Indianapolis according to our data. United Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 6 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 2 per day as of January 2026. The most frequent departure time is 9:00AM, with 100% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of January 2026, there are 18 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

There are 5 operators available for flights from Indianapolis Airport to San Francisco Airport as of January 2026.

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$72 Cheap Flights from Indianapolis to San Francisco in 2026

Q: What is the typical price of a round-trip flight between Indianapolis and San Francisco?

Prices are currently low for flights on this route. Typical prices usually range from $320 to $516. The lowest price recently found on this route was $269.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Indianapolis to San Francisco

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:10 am - 2:21 pm

IND

SFO

10h 11m

1 stop

9:00 am - 5:50 am

SFO

IND

17h 50m

1 stop

$269Alaska Airlines

Thu, Apr 23 - Mon, Apr 27

4:30 pm - 12:54 pm

IND

SFO

23h 24m

2 stops

6:15 am - 8:02 pm

SFO

IND

10h 47m

1 stop

$270Frontier

Sun, Feb 1 - Fri, Feb 20

12:38 pm - 12:38 pm

IND

SFO

27h 00m

2 stops

7:00 am - 3:35 pm

SFO

IND

29h 35m

1 stop

$272Frontier

Mon, Feb 2 - Sat, Feb 7

8:33 pm - 12:29 am

IND

SFO

6h 56m

1 stop

10:38 pm - 11:16 am

SFO

IND

9h 38m

1 stop

$275Frontier

Tue, Mar 10 - Sat, Mar 21

4:30 pm - 12:28 am

IND

SFO

10h 58m

1 stop

6:15 am - 8:02 pm

SFO

IND

10h 47m

1 stop

$276Frontier

Thu, Feb 5 - Fri, Feb 20

12:38 pm - 11:41 pm

IND

SFO

38h 03m

2 stops

8:48 am - 8:07 pm

SFO

IND

8h 19m

1 stop

$277Frontier

Fri, Jan 30 - Thu, Feb 19

4:30 pm - 11:22 am

IND

SFO

21h 52m

2 stops

7:00 am - 3:35 pm

SFO

IND

29h 35m

1 stop

$278Frontier

Thu, Jan 29 - Wed, Feb 4

9:58 am - 12:05 pm

IND

SFO

5h 07mnonstop

12:43 am - 10:48 am

SFO

IND

7h 05m

1 stop

$279United Airlines

Fri, Feb 6 - Sat, Feb 7

8:27 pm - 8:10 pm

IND

SFO

26h 43m

1 stop

9:00 pm - 7:42 pm

SFO

IND

19h 42m

1 stop

$280Frontier

Thu, Apr 2 - Mon, Apr 6

4:30 pm - 12:28 am

IND

SFO

10h 58m

1 stop

7:00 am - 3:35 pm

SFO

IND

29h 35m

1 stop

$281Frontier

Thu, Jan 29 - Wed, Feb 4

United Airlines flights from Indianapolis to San Francisco

Our best United Airlines deals on Indianapolis to San Francisco flight tickets

United Airlines

Feb 6

IND9:58 amIndianapolis

5h 07m

SFO12:05 pmSan Francisco

Feb 7

SFO12:43 amSan Francisco

7h 05m

1 stop

IND10:48 amIndianapolis

$279

United Airlines

Feb 19

IND10:10 amIndianapolis

5h 10m

SFO12:20 pmSan Francisco

Feb 22

SFO4:40 pmSan Francisco

4h 19m

IND11:59 pmIndianapolis

$297

United Airlines

Feb 12

IND6:00 amIndianapolis

7h 50m

1 stop

SFO10:50 amSan Francisco

Feb 15

SFO4:40 pmSan Francisco

4h 19m

IND11:59 pmIndianapolis

$298

Alaska Airlines flights from Indianapolis to San Francisco

Our best Alaska Airlines deals on Indianapolis to San Francisco flight tickets

Alaska Airlines

Apr 23

IND7:10 amIndianapolis

10h 11m

1 stop

SFO2:21 pmSan Francisco

Apr 27

SFO9:00 amSan Francisco

17h 50m

1 stop

IND5:50 amIndianapolis

$269

Alaska Airlines

Jan 29

IND7:00 amIndianapolis

10h 00m

1 stop

SFO2:00 pmSan Francisco

Feb 6

SFO7:00 amSan Francisco

9h 05m

1 stop

IND7:05 pmIndianapolis

$284

Alaska Airlines

Mar 4

IND7:57 pmIndianapolis

17h 40m

1 stop

SFO10:37 amSan Francisco

Mar 16

SFO8:47 pmSan Francisco

19h 09m

1 stop

IND6:56 pmIndianapolis

$289

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 4/23

7:10 am-2:21 pm

1 stop10h 11m

San Francisco

Mon 4/27

9:00 am-5:50 am

1 stop17h 50m

$269

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sun 2/1

4:30 pm-12:54 pm

2 stops23h 24m

San Francisco

Fri 2/20

6:15 am-8:02 pm

1 stop10h 47m

$270

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 2/2

12:38 pm-12:38 pm

2 stops27h 00m

San Francisco

Sat 2/7

7:00 am-3:35 pm

1 stop29h 35m

$272

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Tue 3/10

8:33 pm-12:29 am

1 stop6h 56m

San Francisco

Sat 3/21

10:38 pm-11:16 am

1 stop9h 38m

$275

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 2/5

4:30 pm-12:28 am

1 stop10h 58m

San Francisco

Fri 2/20

6:15 am-8:02 pm

1 stop10h 47m

$276

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 1/30

12:38 pm-11:41 pm

2 stops38h 03m

San Francisco

Thu 2/19

8:48 am-8:07 pm

1 stop8h 19m

$277

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/29

4:30 pm-11:22 am

2 stops21h 52m

San Francisco

Wed 2/4

7:00 am-3:35 pm

1 stop29h 35m

$278

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 2/6

9:58 am-12:05 pm

Nonstop5h 07m

San Francisco

Sat 2/7

12:43 am-10:48 am

1 stop7h 05m

$279

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 4/2

8:27 pm-8:10 pm

1 stop26h 43m

San Francisco

Mon 4/6

9:00 pm-7:42 pm

1 stop19h 42m

$280

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/29

4:30 pm-12:28 am

1 stop10h 58m

San Francisco

Wed 2/4

7:00 am-3:35 pm

1 stop29h 35m

$281

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the typical price of a round-trip flight between Indianapolis and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $336.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $479. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $779.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $534. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $371 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $304 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of January 2026, prices for Indianapolis to San Francisco flights are approximately 9% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found	$363
Fastest flight time	4h 57m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $363. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $375.

The fastest flight from Indianapolis to San Francisco takes 4h 57m

Direct flights go from Indianapolis to San Francisco every day.

There is 1 airport in San Francisco. From Indianapolis there are direct flights to San Francisco (SFO).

Search flight deals

How far is Indianapolis to San Francisco by plane?
There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 4h 57m.
When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?
Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?
There are 5 operators available for flights from Indianapolis Airport to San Francisco Airport as of January 2026.
How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to San Francisco is Airbus A319, representing 30.37% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 27.10%, Boeing 737-800 at 14.72%, and Airbus A320-100/200 at 13.79%.
What is the most popular airline from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Indianapolis to San Francisco is United Airlines, representing 60% of all bookings. The subsequent popular airlines are Delta at 14%, American Airlines at 10%, and Southwest at 9%.

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $100	Free Cancellation	Rating 5.7 3,057 reviews	Search Frontier flights
Delta	PriceFrom $165	Free Cancellation	Rating 7.9 8,051 reviews	Search Delta flights
American Airlines	PriceFrom $238	Free Cancellation	Rating 7.2 11,136 reviews	Search American Airlines flights
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 9,164 reviews	Search United Airlines flights
Southwest	PriceFrom $284	Free Cancellation	Rating 8.0 4,258 reviews	Search Southwest flights

United Airlines Flights From Indianapolis to San Francisco
United Airlines flight deals from Indianapolis to San Francisco start from $269 round-trip. Over the 6 United Airlines flights for this route in a normal week, average airfare is usually $401 round-trip - but some users have found much cheaper deals with momondo.

Santa Cruz

Carmel-by-the-Sea

Modesto

Sonoma

Bodega Bay

Roseville

Hayward

Calistoga

Big Sur

Santa Clara

Berkeley

Walnut Creek

Fremont

Half Moon Bay

Daly City

Vallejo

Livermore

Salinas

Sunnyvale

Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sat 2/14

Sat 2/21

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Airports servicing California

Popular cities in the United States

Flights to New Yorkfrom $49

Flights to Los Angelesfrom $41

Flights to Miamifrom $45

Flights to Chicagofrom $54

Flights to Orlandofrom $33

Flights to Las Vegasfrom $21

Flights to Washington, D.C.from $54

Flights to Bostonfrom $50

Flights to Atlantafrom $36

Flights to Dallasfrom $50

Flights to Seattlefrom $54

Flights to Denverfrom $56

Cheap flights from Indianapolis to San Francisco from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 2/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Indianapolis to San Francisco

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

United Airlines flights from Indianapolis to San Francisco

Our best United Airlines deals on Indianapolis to San Francisco flight tickets

Alaska Airlines flights from Indianapolis to San Francisco

Our best Alaska Airlines deals on Indianapolis to San Francisco flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

What is the typical price of a round-trip flight between Indianapolis and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $336.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $479. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $779.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $534. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of January 2026, prices for Indianapolis to San Francisco flights are approximately 9% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Frontier, Southwest, and Delta are the most popular carriers operating from Indianapolis to San Francisco

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Chicago (ORD) offer the lowest average round-trip price of $482.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Las Vegas (LAS) has the shortest average layover time for this route: 1h 20m.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 2 per day as of January 2026. The most frequent departure time is 9:00AM, with 100% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of January 2026, there are 18 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

When to book flights from Indianapolis to San Francisco

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

How far is Indianapolis to San Francisco by plane?

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

What documentation or ID do you need to fly to San Francisco Airport?

What is the most popular plane model from Indianapolis to San Francisco?

What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

United Airlines Flights From Indianapolis to San Francisco

Traveling to a place near San Francisco?

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

How can momondo help me find flights from Indianapolis to San Francisco?

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States