Cheap flights from Indianapolis to San Francisco from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Indianapolis to San Francisco (IND-SFO)

Cheap round-trip flights

United Airlines Logo
4:36 pm - 9:20 pmIND-SFO
7h 44m1 stop
United Airlines Logo
11:20 pm - 6:46 amSFO-IND
4h 26mnonstop
$279United Airlines
Find Deal
jue., oct. 2 - lun., oct. 6
 Logo
10:17 am - 9:21 pmIND-SFO
14h 04m2 stops
 Logo
5:45 am - 7:28 pmSFO-IND
10h 43m1 stop
jue., sep. 18 - jue., sep. 25
Southwest Logo
6:50 am - 2:10 pmIND-SFO
10h 20m2 stops
Southwest Logo
12:30 pm - 11:00 pmSFO-IND
7h 30m1 stop
$282Southwest
Find Deal
mié., oct. 29 - mié., nov. 5
Delta Logo
6:45 am - 1:50 pmIND-SFO
10h 05m1 stop
Delta Logo
12:10 am - 11:44 amSFO-IND
8h 34m1 stop
$284Delta
Find Deal
mié., dic. 24 - lun., dic. 29
Frontier Logo
8:51 pm - 2:22 pmIND-SFO
20h 31m1 stop
Frontier Logo
6:34 am - 8:06 pmSFO-IND
10h 32m1 stop
$285Frontier
Find Deal
jue., oct. 16 - lun., oct. 20
Delta Logo
8:00 am - 12:54 pmIND-SFO
7h 54m1 stop
Delta Logo
6:00 am - 5:02 pmSFO-IND
8h 02m1 stop
$289Delta
Find Deal
jue., dic. 25 - dom., ene. 18
Southwest Logo
6:50 am - 2:10 pmIND-SFO
10h 20m2 stops
Southwest Logo
6:10 am - 11:00 pmSFO-IND
13h 50m2 stops
$299Southwest
Find Deal
mié., oct. 29 - mié., nov. 5
Frontier Logo
7:32 pm - 9:21 pmIND-SFO
28h 49m2 stops
Frontier Logo
11:57 pm - 6:25 pmSFO-IND
15h 28m1 stop
$306Frontier
Find Deal
lun., sep. 8 - dom., sep. 14
American Airlines Logo
6:00 am - 9:45 amIND-SFO
6h 45m1 stop
American Airlines Logo
12:47 am - 10:20 amSFO-IND
6h 33m1 stop
$314American Airlines
Find Deal
mié., sep. 3 - mar., sep. 9
American Airlines Logo
3:43 pm - 9:51 pmIND-SFO
9h 08m1 stop
American Airlines Logo
11:36 pm - 11:24 amSFO-IND
8h 48m1 stop
$337American Airlines
Find Deal
vie., oct. 10 - dom., oct. 12

Southwest flights from Indianapolis to San Francisco

Our best Southwest deals on Indianapolis to San Francisco flight tickets
Southwest
Oct 29
IND6:50 amIndianapolis
10h 20m
2 stops
SFO2:10 pmSan Francisco
Nov 5
SFO12:30 pmSan Francisco
7h 30m
1 stop
IND11:00 pmIndianapolis
Southwest
Oct 29
IND6:50 amIndianapolis
10h 20m
2 stops
SFO2:10 pmSan Francisco
Nov 5
SFO6:10 amSan Francisco
13h 50m
2 stops
IND11:00 pmIndianapolis
Southwest
Oct 18
IND5:05 pmIndianapolis
6h 40m
1 stop
SFO8:45 pmSan Francisco
Oct 20
SFO9:05 pmSan Francisco
10h 30m
1 stop
IND10:35 amIndianapolis

Delta flights from Indianapolis to San Francisco

Our best Delta deals on Indianapolis to San Francisco flight tickets
Delta
Dec 24
IND6:45 amIndianapolis
10h 05m
1 stop
SFO1:50 pmSan Francisco
Dec 29
SFO12:10 amSan Francisco
8h 34m
1 stop
IND11:44 amIndianapolis
Delta
Dec 25
IND8:00 amIndianapolis
7h 54m
1 stop
SFO12:54 pmSan Francisco
Jan 18
SFO6:00 amSan Francisco
8h 02m
1 stop
IND5:02 pmIndianapolis
Delta
Sep 3
IND6:00 amIndianapolis
7h 10m
1 stop
SFO10:10 amSan Francisco
Sep 17
SFO1:20 pmSan Francisco
6h 38m
1 stop
IND10:58 pmIndianapolis

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 21, 2025.
Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

jue. 10/2

4:36 pm-9:20 pm

1 stop7h 44m

San Francisco

lun. 10/6

11:20 pm-6:46 am

Nonstop4h 26m

$279

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

jue. 9/18

10:17 am-9:21 pm

2 stops14h 04m

San Francisco

jue. 9/25

5:45 am-7:28 pm

1 stop10h 43m

$281

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mié. 10/29

6:50 am-2:10 pm

2 stops10h 20m

San Francisco

mié. 11/5

12:30 pm-11:00 pm

1 stop7h 30m

$282

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mié. 12/24

6:45 am-1:50 pm

1 stop10h 05m

San Francisco

lun. 12/29

12:10 am-11:44 am

1 stop8h 34m

$284

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

jue. 10/16

8:51 pm-2:22 pm

1 stop20h 31m

San Francisco

lun. 10/20

6:34 am-8:06 pm

1 stop10h 32m

$285

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

jue. 12/25

8:00 am-12:54 pm

1 stop7h 54m

San Francisco

dom. 1/18

6:00 am-5:02 pm

1 stop8h 02m

$289

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mié. 10/29

6:50 am-2:10 pm

2 stops10h 20m

San Francisco

mié. 11/5

6:10 am-11:00 pm

2 stops13h 50m

$299

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

lun. 9/8

7:32 pm-9:21 pm

2 stops28h 49m

San Francisco

dom. 9/14

11:57 pm-6:25 pm

1 stop15h 28m

$306

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

mié. 9/3

6:00 am-9:45 am

1 stop6h 45m

San Francisco

mar. 9/9

12:47 am-10:20 am

1 stop6h 33m

$314

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

vie. 10/10

3:43 pm-9:51 pm

1 stop9h 08m

San Francisco

dom. 10/12

11:36 pm-11:24 am

1 stop8h 48m

$337

Flights are sorted by cheapest round-trip flights first.

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See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $359.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $476. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $854.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $544. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $374 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $328 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of August 2025, prices for Indianapolis to San Francisco flights are approximately 13% cheaper when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

$387

Fastest flight time

4h 45m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $387. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $469.
The fastest flight from Indianapolis to San Francisco takes 4h 45m
Direct flights go from Indianapolis to San Francisco every day.
There is 1 airport near San Francisco: San Francisco (SFO)
  • How far is Indianapolis to San Francisco by plane?

    There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 4h 45m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

    Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Francisco?

  • What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $130Free CancellationRating
5.8
3,207 reviews
Search Frontier flights
Sun Country AirPriceFrom $192Free CancellationRating
6.9
333 reviews
Search Sun Country Air flights
DeltaPriceFrom $236Free CancellationRating
7.9
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $236Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $269Free CancellationRating
7.4
8,930 reviews
Search United Airlines flights
SouthwestPriceFrom $288Free CancellationRating
8.0
4,245 reviews
Search Southwest flights
  • United Airlines Flights From Indianapolis to San Francisco

    United Airlines flight deals from Indianapolis to San Francisco start from $269 round-trip. Over the 7 United Airlines flights for this route in a normal week, average airfare is usually $419 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Calistoga
Sonoma
Hayward
Bodega Bay
Roseville
Santa Clara
Big Sur
Daly City
Fremont
Berkeley
Walnut Creek
Half Moon Bay
Vallejo
South San Francisco
Redwood City
Pacific Grove
Sunnyvale

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
mar. 8/26
mar. 9/2

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