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Cheap flights from Indianapolis to San Francisco from $153

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 5/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Indianapolis to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:49 pm - 10:41 am
IND
-
SFO
18h 52m
1 stop
Frontier Logo
6:00 am - 12:46 pm
SFO
-
IND
27h 46m
2 stops
$278Frontier
Mon, May 11 - Mon, May 18
Frontier Logo
6:49 pm - 8:30 am
IND
-
SFO
16h 41m
1 stop
Frontier Logo
6:00 am - 7:54 pm
SFO
-
IND
10h 54m
1 stop
$279Frontier
Fri, May 15 - Sun, May 17
Frontier Logo
8:39 pm - 12:23 am
IND
-
SFO
6h 44m
1 stop
Frontier Logo
6:00 am - 7:54 pm
SFO
-
IND
10h 54m
1 stop
$280Frontier
Mon, May 11 - Mon, May 18
Frontier Logo
7:10 pm - 10:15 am
IND
-
SFO
18h 05m
1 stop
Frontier Logo
6:00 am - 8:08 pm
SFO
-
IND
11h 08m
1 stop
$281Frontier
Wed, Aug 12 - Sat, Aug 15
Frontier Logo
12:14 pm - 7:34 pm
IND
-
SFO
10h 20m
1 stop
Frontier Logo
12:52 pm - 7:54 pm
SFO
-
IND
28h 02m
1 stop
$282Frontier
Wed, May 13 - Sat, May 16
Frontier Logo
12:14 pm - 7:34 pm
IND
-
SFO
10h 20m
1 stop
Frontier Logo
11:29 am - 12:54 pm
SFO
-
IND
22h 25m
2 stops
$283Frontier
Fri, May 29 - Tue, Jun 9
Frontier Logo
6:49 pm - 10:41 am
IND
-
SFO
18h 52m
1 stop
Frontier Logo
3:33 pm - 5:54 pm
SFO
-
IND
23h 21m
1 stop
$284Frontier
Mon, May 11 - Sun, May 17
Multiple Airlines Logo
8:39 pm - 12:23 am
IND
-
SFO
6h 44m
1 stop
Multiple Airlines Logo
8:41 pm - 10:35 pm
SFO
-
IND
22h 54m
2 stops
$285Multiple Airlines
Sat, May 30 - Sun, Jun 7
Multiple Airlines Logo
8:39 pm - 12:23 am
IND
-
SFO
6h 44m
1 stop
Multiple Airlines Logo
10:50 pm - 10:35 pm
SFO
-
IND
20h 45m
2 stops
$287Multiple Airlines
Fri, Jun 5 - Sun, Jun 7
Multiple Airlines Logo
8:39 pm - 12:23 am
IND
-
SFO
6h 44m
1 stop
Multiple Airlines Logo
10:45 pm - 11:09 pm
SFO
-
IND
21h 24m
1 stop
$289Multiple Airlines
Sun, May 24 - Wed, Jun 3

Alaska Airlines flights from Indianapolis to San Francisco

Our best Alaska Airlines deals on Indianapolis to San Francisco flight tickets
Alaska Airlines
Sep 9
IND7:00 amIndianapolis
9h 03m
1 stop
SFO1:03 pmSan Francisco
Sep 15
SFO1:43 pmSan Francisco
12h 31m
1 stop
IND5:14 amIndianapolis
$309
Alaska Airlines
Sep 19
IND7:00 amIndianapolis
10h 27m
1 stop
SFO2:27 pmSan Francisco
Sep 25
SFO7:00 amSan Francisco
19h 14m
1 stop
IND5:14 amIndianapolis
$329
Alaska Airlines
May 12
IND7:10 amIndianapolis
10h 11m
1 stop
SFO2:21 pmSan Francisco
May 27
SFO6:00 amSan Francisco
8h 39m
1 stop
IND5:39 pmIndianapolis
$364

Frontier flights from Indianapolis to San Francisco

Our best Frontier deals on Indianapolis to San Francisco flight tickets
Frontier
May 11
IND6:49 pmIndianapolis
18h 52m
1 stop
SFO10:41 amSan Francisco
May 18
SFO6:00 amSan Francisco
27h 46m
2 stops
IND12:46 pmIndianapolis
$278
Frontier
May 15
IND6:49 pmIndianapolis
16h 41m
1 stop
SFO8:30 amSan Francisco
May 17
SFO6:00 amSan Francisco
10h 54m
1 stop
IND7:54 pmIndianapolis
$279
Frontier
May 11
IND8:39 pmIndianapolis
6h 44m
1 stop
SFO12:23 amSan Francisco
May 18
SFO6:00 amSan Francisco
10h 54m
1 stop
IND7:54 pmIndianapolis
$280

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 5/11

6:49 pm-10:41 am

1 stop18h 52m

San Francisco

Mon 5/18

6:00 am-12:46 pm

2 stops27h 46m

$278

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 5/15

6:49 pm-8:30 am

1 stop16h 41m

San Francisco

Sun 5/17

6:00 am-7:54 pm

1 stop10h 54m

$279
Quickest round-trip

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 5/11

8:39 pm-12:23 am

1 stop6h 44m

San Francisco

Mon 5/18

6:00 am-7:54 pm

1 stop10h 54m

$280

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 8/12

7:10 pm-10:15 am

1 stop18h 05m

San Francisco

Sat 8/15

6:00 am-8:08 pm

1 stop11h 08m

$281

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 5/13

12:14 pm-7:34 pm

1 stop10h 20m

San Francisco

Sat 5/16

12:52 pm-7:54 pm

1 stop28h 02m

$282

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 5/29

12:14 pm-7:34 pm

1 stop10h 20m

San Francisco

Tue 6/9

11:29 am-12:54 pm

2 stops22h 25m

$283

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 5/11

6:49 pm-10:41 am

1 stop18h 52m

San Francisco

Sun 5/17

3:33 pm-5:54 pm

1 stop23h 21m

$284

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sat 5/30

8:39 pm-12:23 am

1 stop6h 44m

San Francisco

Sun 6/7

8:41 pm-10:35 pm

2 stops22h 54m

$285

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 6/5

8:39 pm-12:23 am

1 stop6h 44m

San Francisco

Sun 6/7

10:50 pm-10:35 pm

2 stops20h 45m

$287

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Sun 5/24

8:39 pm-12:23 am

1 stop6h 44m

San Francisco

Wed 6/3

10:45 pm-11:09 pm

1 stop21h 24m

$289

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of September, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $359.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $459. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $728.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $511. Flights in the evening are often more expensive with an average ticket price of $1,017.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight from Indianapolis to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $307 on momondo.

How have Indianapolis to San Francisco flight prices changed over time?

As of April 2026, prices for Indianapolis to San Francisco flights are approximately 32% cheaper when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

$303

Fastest flight time

4h 42m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $303. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $438.
The fastest flight from Indianapolis to San Francisco takes 4h 42m
Direct flights go from Indianapolis to San Francisco every day.
There is 1 airport in San Francisco. From Indianapolis there are direct flights to San Francisco (SFO).
Search flight deals

Frequently asked questions about flying from Indianapolis to San Francisco

  • How far is Indianapolis to San Francisco by plane?

    There are 1942.5 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 4h 42m.

  • When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

    Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

  • How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indianapolis to San Francisco?

  • What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $107Free CancellationRating
5.6
2,970 reviews
Search Frontier flights
DeltaPriceFrom $144Free CancellationRating
7.9
8,467 reviews
Search Delta flights
American AirlinesPriceFrom $237Free CancellationRating
7.1
11,680 reviews
Search American Airlines flights
United AirlinesPriceFrom $269Free CancellationRating
7.4
9,680 reviews
Search United Airlines flights
JetBluePriceFrom $278Free CancellationRating
7.1
2,968 reviews
Search JetBlue flights
SouthwestPriceFrom $284Free CancellationRating
8.0
4,315 reviews
Search Southwest flights

  • United Airlines Flights From Indianapolis to San Francisco

    United Airlines flight deals from Indianapolis to San Francisco start from $269 round-trip. Over the 2 United Airlines flights for this route in a normal week, average airfare is usually $395 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Vallejo
Fremont
Big Sur
Calistoga
Daly City
South San Francisco
Pacific Grove
Sunnyvale
Salinas
Milpitas

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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