What is the cheapest airline that flies from Indianapolis to San Francisco?

Delta, Frontier, and Southwest are the most popular carriers operating from Indianapolis to San Francisco

How many flights depart from Indianapolis to San Francisco on average per week?

As of October 2025, there are 38 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 21% of flights taking off on this day.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Dallas (DFW) has the shortest average layover time for this route: 1h 00m.

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 20% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Detroit (DTW) offer the lowest average round-trip price of $313.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 5 per day as of October 2025. The most frequent departure time is 6:00AM, with 64% of daily flights leaving at noon.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

What airlines fly to San Francisco?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to San Francisco from Indianapolis according to our data. United Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 9 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

There are 6 operators available for flights from Indianapolis Airport to San Francisco Airport as of October 2025.

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$144 Cheap Flights from Indianapolis to San Francisco in 2025/26

Q: What is the typical price of a round-trip flight between Indianapolis and San Francisco?

Prices are currently low for flights on this route. Typical prices usually range from $319 to $555. The lowest price recently found on this route was $269.

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Cheap round-trip flights

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6:00 pm - 8:04 pmIND-SFO

5h 04mnonstop

9:42 am - 5:00 pmSFO-IND

4h 18mnonstop

$269United Airlines

Find Deal

Thu, Nov 6 - Wed, Nov 12

7:30 am - 1:25 pmIND-SFO

8h 55m1 stop

6:34 am - 5:35 pmSFO-IND

8h 01m1 stop

$270Multiple Airlines

Find Deal

Fri, Oct 31 - Sat, Nov 1

8:39 pm - 5:43 pmIND-SFO

24h 04m2 stops

8:09 pm - 7:44 pmSFO-IND

20h 35m1 stop

$273Frontier

Find Deal

Thu, Oct 30 - Sun, Nov 2

7:02 am - 11:17 amIND-SFO

7h 15m1 stop

10:30 am - 11:44 pmSFO-IND

10h 14m2 stops

$278Delta

Find Deal

Wed, Nov 12 - Tue, Nov 18

8:39 pm - 2:40 pmIND-SFO

21h 01m1 stop

8:09 pm - 7:44 pmSFO-IND

20h 35m1 stop

$282Frontier

Find Deal

Thu, Oct 30 - Sun, Nov 2

7:05 am - 11:25 amIND-SFO

7h 20m1 stop

12:30 pm - 11:00 pmSFO-IND

7h 30m1 stop

$284Southwest

Find Deal

Fri, Dec 12 - Wed, Dec 17

5:55 pm - 10:44 pmIND-SFO

7h 49m1 stop

5:50 am - 5:29 pmSFO-IND

8h 39m1 stop

$289Delta

Find Deal

Wed, Nov 12 - Thu, Nov 27

11:20 am - 6:05 pmIND-SFO

9h 45m2 stops

5:05 am - 5:05 pmSFO-IND

9h 00m2 stops

$299Southwest

Find Deal

Mon, Jan 12 - Wed, Jan 14

7:21 pm - 10:44 amIND-SFO

18h 23m1 stop

8:00 am - 6:21 pmSFO-IND

7h 21m1 stop

$313Alaska Airlines

Find Deal

Tue, Nov 4 - Tue, Nov 11

7:00 am - 9:35 pmIND-SFO

17h 35m2 stops

7:40 pm - 5:30 pmSFO-IND

18h 50m1 stop

$322Alaska Airlines

Find Deal

Wed, Feb 11 - Mon, Feb 16

Delta flights from Indianapolis to San Francisco

Our best Delta deals on Indianapolis to San Francisco flight tickets

Delta

Nov 12

IND7:02 amIndianapolis

7h 15m

1 stop

SFO11:17 amSan Francisco

Nov 18

SFO10:30 amSan Francisco

10h 14m

2 stops

IND11:44 pmIndianapolis

$278

Find similar

Delta

Nov 12

IND5:55 pmIndianapolis

7h 49m

1 stop

SFO10:44 pmSan Francisco

Nov 27

SFO5:50 amSan Francisco

8h 39m

1 stop

IND5:29 pmIndianapolis

$289

Find similar

Delta

Nov 15

IND7:02 amIndianapolis

11h 55m

2 stops

SFO3:57 pmSan Francisco

Nov 16

SFO9:30 pmSan Francisco

8h 30m

1 stop

IND9:00 amIndianapolis

$298

Find similar

Southwest flights from Indianapolis to San Francisco

Our best Southwest deals on Indianapolis to San Francisco flight tickets

Southwest

Dec 12

IND7:05 amIndianapolis

7h 20m

1 stop

SFO11:25 amSan Francisco

Dec 17

SFO12:30 pmSan Francisco

7h 30m

1 stop

IND11:00 pmIndianapolis

$284

Find similar

Southwest

Jan 12

IND11:20 amIndianapolis

9h 45m

2 stops

SFO6:05 pmSan Francisco

Jan 14

SFO5:05 amSan Francisco

9h 00m

2 stops

IND5:05 pmIndianapolis

$299

Find similar

Southwest

Nov 12

IND5:50 amIndianapolis

9h 00m

2 stops

SFO11:50 amSan Francisco

Nov 19

SFO6:10 amSan Francisco

13h 50m

2 stops

IND11:00 pmIndianapolis

$305

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 11/6

6:00 pm-8:04 pm

Nonstop5h 04m

San Francisco

Wed 11/12

9:42 am-5:00 pm

Nonstop4h 18m

$269

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 10/31

7:30 am-1:25 pm

1 stop8h 55m

San Francisco

Sat 11/1

6:34 am-5:35 pm

1 stop8h 01m

$270

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 10/30

8:39 pm-5:43 pm

2 stops24h 04m

San Francisco

Sun 11/2

8:09 pm-7:44 pm

1 stop20h 35m

$273

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 11/12

7:02 am-11:17 am

1 stop7h 15m

San Francisco

Tue 11/18

10:30 am-11:44 pm

2 stops10h 14m

$278

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 10/30

8:39 pm-2:40 pm

1 stop21h 01m

San Francisco

Sun 11/2

8:09 pm-7:44 pm

1 stop20h 35m

$282

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 12/12

7:05 am-11:25 am

1 stop7h 20m

San Francisco

Wed 12/17

12:30 pm-11:00 pm

1 stop7h 30m

$284

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 11/12

5:55 pm-10:44 pm

1 stop7h 49m

San Francisco

Thu 11/27

5:50 am-5:29 pm

1 stop8h 39m

$289

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 1/12

11:20 am-6:05 pm

2 stops9h 45m

San Francisco

Wed 1/14

5:05 am-5:05 pm

2 stops9h 00m

$299

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Tue 11/4

7:21 pm-10:44 am

1 stop18h 23m

San Francisco

Tue 11/11

8:00 am-6:21 pm

1 stop7h 21m

$313

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 2/11

7:00 am-9:35 pm

2 stops17h 35m

San Francisco

Mon 2/16

7:40 pm-5:30 pm

1 stop18h 50m

$322

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the typical price of a round-trip flight between Indianapolis and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $337.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $475. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $786.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $527. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $369 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $319 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of October 2025, prices for Indianapolis to San Francisco flights are approximately 41% more expensive when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found	$273
Fastest flight time	4h 50m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $273. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $322.

The fastest flight from Indianapolis to San Francisco takes 4h 50m

Direct flights go from Indianapolis to San Francisco every day.

There is 1 airport near San Francisco: San Francisco (SFO)

Search flight deals

How far is Indianapolis to San Francisco by plane?
There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 5h 04m.
When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?
Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?
There are 6 operators available for flights from Indianapolis Airport to San Francisco Airport as of October 2025.
How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to San Francisco is Boeing 737-800, representing 42.77% of all bookings. The subsequent popular models are Airbus A319 at 24.59%, Boeing 737 MAX 8 at 21.69%, and Airbus A320-100/200 at 2.07%.
What is the most popular airline from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Indianapolis to San Francisco is United Airlines, representing 57% of all bookings. The subsequent popular airlines are Delta at 17%, American Airlines at 12%, and Southwest at 7%.

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $129	Free Cancellation	Rating 5.8 3,137 reviews	Search Frontier flights
Sun Country Air	PriceFrom $149	Free Cancellation	Rating 6.9 335 reviews	Search Sun Country Air flights
Delta	PriceFrom $229	Free Cancellation	Rating 7.9 7,980 reviews	Search Delta flights
American Airlines	PriceFrom $238	Free Cancellation	Rating 7.2 11,040 reviews	Search American Airlines flights
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 8,982 reviews	Search United Airlines flights
Southwest	PriceFrom $284	Free Cancellation	Rating 8.0 4,241 reviews	Search Southwest flights

Southwest Flights From Indianapolis to San Francisco
Southwest flight deals from Indianapolis to San Francisco start from $284 round-trip. Over the 3 Southwest flights for this route in a normal week, average airfare is usually $435 round-trip - but some users have found much cheaper deals with momondo.
United Airlines Flights From Indianapolis to San Francisco
United Airlines is also a popular choice for this route. United Airlines flight deals for Indianapolis to San Francisco start from as low as $269 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $412. United Airlines operates 15 flights to San Francisco from Indianapolis in an average week. Users have rated it 7.4/10 across 8,982 reviews.

Santa Cruz

Carmel-by-the-Sea

Modesto

Sonoma

Bodega Bay

Calistoga

Roseville

Hayward

Big Sur

Santa Clara

Fremont

Daly City

Berkeley

Vallejo

Walnut Creek

Half Moon Bay

Salinas

Turlock

South San Francisco

Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Indianapolis to San Francisco from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Find the cheapest flights from Indianapolis to San Francisco

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Delta flights from Indianapolis to San Francisco

Our best Delta deals on Indianapolis to San Francisco flight tickets

Southwest flights from Indianapolis to San Francisco

Our best Southwest deals on Indianapolis to San Francisco flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $337.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Friday when prices can be found for as low as $475. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $786.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $527. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of October 2025, prices for Indianapolis to San Francisco flights are approximately 41% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Delta, Frontier, and Southwest are the most popular carriers operating from Indianapolis to San Francisco

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 20% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Detroit (DTW) offer the lowest average round-trip price of $313.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Dallas (DFW) has the shortest average layover time for this route: 1h 00m.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 5 per day as of October 2025. The most frequent departure time is 6:00AM, with 64% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of October 2025, there are 38 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 21% of flights taking off on this day.

When to book flights from Indianapolis to San Francisco

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

How far is Indianapolis to San Francisco by plane?

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

What documentation or ID do you need to fly to San Francisco Airport?

What is the most popular plane model from Indianapolis to San Francisco?

What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

Southwest Flights From Indianapolis to San Francisco

United Airlines Flights From Indianapolis to San Francisco

Traveling to a place near San Francisco?

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

How can momondo help me find flights from Indianapolis to San Francisco?

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down