Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Dallas (DFW) offer the lowest average round-trip price of $378.

What airlines fly to San Francisco?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to San Francisco from Indianapolis according to our data. United Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 7 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 29% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Alaska Airlines, Southwest, and Frontier are the most popular carriers operating from Indianapolis to San Francisco

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 2 per day as of December 2025. The most frequent departure time is 6:00PM, with 50% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of December 2025, there are 14 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 50% of flights taking off on this day.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Dallas (DFW) has the shortest average layover time for this route: 1h 00m.

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

There are 5 operators available for flights from Indianapolis Airport to San Francisco Airport as of December 2025.

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$85 Cheap Flights from Indianapolis to San Francisco in 2025/26

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7:20 am - 9:49 pmIND-SFO

17h 29m1 stop

6:54 pm - 12:18 amSFO-IND

26h 24m2 stops

$271Multiple Airlines

Find Deal

Mon, Jan 5 - Wed, Jan 7

8:55 pm - 8:47 pmIND-SFO

26h 52m1 stop

8:38 am - 4:44 pmSFO-IND

29h 06m1 stop

$274Multiple Airlines

Find Deal

Fri, Jan 9 - Sun, Jan 11

7:00 am - 2:00 pmIND-SFO

10h 00m1 stop

11:20 pm - 3:09 pmSFO-IND

12h 49m1 stop

$277Multiple Airlines

Find Deal

Wed, Jan 7 - Wed, Jan 14

7:19 pm - 12:24 amIND-SFO

8h 05m1 stop

6:30 am - 7:53 pmSFO-IND

10h 23m1 stop

$278Frontier

Find Deal

Thu, Dec 4 - Fri, Dec 12

9:00 am - 1:29 pmIND-SFO

7h 29m1 stop

4:41 pm - 12:01 amSFO-IND

4h 20mnonstop

$279United Airlines

Find Deal

Thu, Jan 8 - Wed, Jan 14

8:48 pm - 12:24 amIND-SFO

30h 36m1 stop

8:43 am - 4:34 pmSFO-IND

28h 51m1 stop

$280Multiple Airlines

Find Deal

Fri, Dec 5 - Thu, Dec 11

6:40 am - 2:20 pmIND-SFO

10h 40m2 stops

9:30 pm - 10:30 amSFO-IND

10h 00m1 stop

$281Southwest

Find Deal

Tue, Jan 6 - Sat, Jan 10

8:55 pm - 12:24 amIND-SFO

6h 29m1 stop

8:58 am - 8:00 pmSFO-IND

8h 02m1 stop

$282Frontier

Find Deal

Thu, Jan 8 - Sun, Jan 11

8:48 pm - 12:24 amIND-SFO

30h 36m1 stop

6:30 am - 7:53 pmSFO-IND

10h 23m1 stop

$284Frontier

Find Deal

Fri, Dec 5 - Fri, Dec 12

7:20 am - 9:49 pmIND-SFO

17h 29m1 stop

7:09 pm - 11:33 amSFO-IND

13h 24m2 stops

$285Multiple Airlines

Find Deal

Mon, Jan 5 - Tue, Jan 6

United Airlines flights from Indianapolis to San Francisco

Our best United Airlines deals on Indianapolis to San Francisco flight tickets

United Airlines

May 1

IND7:00 amIndianapolis

8h 18m

1 stop

SFO12:18 pmSan Francisco

May 12

SFO9:00 pmSan Francisco

4h 33m

IND4:33 amIndianapolis

$275

Find similar

United Airlines

Jan 8

IND9:00 amIndianapolis

7h 29m

1 stop

SFO1:29 pmSan Francisco

Jan 14

SFO4:41 pmSan Francisco

4h 20m

IND12:01 amIndianapolis

$279

Find similar

United Airlines

Apr 22

IND3:38 pmIndianapolis

7h 07m

1 stop

SFO7:45 pmSan Francisco

Apr 25

SFO12:45 amSan Francisco

7h 30m

1 stop

IND11:15 amIndianapolis

$302

Find similar

Frontier flights from Indianapolis to San Francisco

Our best Frontier deals on Indianapolis to San Francisco flight tickets

Frontier

Dec 4

IND7:19 pmIndianapolis

8h 05m

1 stop

SFO12:24 amSan Francisco

Dec 7

SFO6:30 amSan Francisco

10h 23m

1 stop

IND7:53 pmIndianapolis

$278

Find similar

Frontier

Jan 8

IND8:55 pmIndianapolis

6h 29m

1 stop

SFO12:24 amSan Francisco

Jan 11

SFO8:58 amSan Francisco

8h 02m

1 stop

IND8:00 pmIndianapolis

$282

Find similar

Frontier

Dec 5

IND8:48 pmIndianapolis

30h 36m

1 stop

SFO12:24 amSan Francisco

Dec 12

SFO6:30 amSan Francisco

10h 23m

1 stop

IND7:53 pmIndianapolis

$284

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momondo Fare Finder

Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

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Route

Depart

Return

Price

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 1/5

7:20 am-9:49 pm

1 stop17h 29m

San Francisco

Wed 1/7

6:54 pm-12:18 am

2 stops26h 24m

$271

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 1/9

8:55 pm-8:47 pm

1 stop26h 52m

San Francisco

Sun 1/11

8:38 am-4:44 pm

1 stop29h 06m

$274

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 1/7

7:00 am-2:00 pm

1 stop10h 00m

San Francisco

Wed 1/14

11:20 pm-3:09 pm

1 stop12h 49m

$277

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 12/4

7:19 pm-12:24 am

1 stop8h 05m

San Francisco

Fri 12/12

6:30 am-7:53 pm

1 stop10h 23m

$278

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/8

9:00 am-1:29 pm

1 stop7h 29m

San Francisco

Wed 1/14

4:41 pm-12:01 am

Nonstop4h 20m

$279

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 12/5

8:48 pm-12:24 am

1 stop30h 36m

San Francisco

Thu 12/11

8:43 am-4:34 pm

1 stop28h 51m

$280

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Tue 1/6

6:40 am-2:20 pm

2 stops10h 40m

San Francisco

Sat 1/10

9:30 pm-10:30 am

1 stop10h 00m

$281

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Thu 1/8

8:55 pm-12:24 am

1 stop6h 29m

San Francisco

Sun 1/11

8:58 am-8:00 pm

1 stop8h 02m

$282

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Fri 12/5

8:48 pm-12:24 am

1 stop30h 36m

San Francisco

Fri 12/12

6:30 am-7:53 pm

1 stop10h 23m

$284

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Mon 1/5

7:20 am-9:49 pm

1 stop17h 29m

San Francisco

Tue 1/6

7:09 pm-11:33 am

2 stops13h 24m

$285

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How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $337.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Thursday when prices can be found for as low as $476. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $732.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $519. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $370 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Indianapolis for as low as $330 on momondo.

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of December 2025, prices for Indianapolis to San Francisco flights are approximately 20% cheaper when compared to flights at the same time last year.

When to book flights from Indianapolis to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found	$225
Fastest flight time	4h 57m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Indianapolis in the past 72 hours is $225. The best round-trip flight deal from Indianapolis to San Francisco found on momondo in the last 72 hours is $386.

The fastest flight from Indianapolis to San Francisco takes 4h 57m

Direct flights go from Indianapolis to San Francisco every day.

There is 1 airport near San Francisco: San Francisco (SFO)

Search flight deals

How far is Indianapolis to San Francisco by plane?
There are 1942.9 mi between Indianapolis and San Francisco. A reasonable flight in good conditions will take 5h 10m.
When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?
Prices for flights from Indianapolis Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?
There are 5 operators available for flights from Indianapolis Airport to San Francisco Airport as of December 2025.
How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indianapolis Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked plane model on the route from Indianapolis to San Francisco is Boeing 737-800, representing 31.01% of all bookings. The subsequent popular models are Airbus A319 at 29.26%, Boeing 737 MAX 8 at 22.67%, and Airbus A320-100/200 at 7.56%.
What is the most popular airline from Indianapolis to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Indianapolis to San Francisco is United Airlines, representing 59% of all bookings. The subsequent popular airlines are Delta at 15%, American Airlines at 12%, and Southwest at 8%.

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $130	Free Cancellation	Rating 5.8 3,094 reviews	Search Frontier flights
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 8,010 reviews	Search Delta flights
American Airlines	PriceFrom $240	Free Cancellation	Rating 7.2 11,041 reviews	Search American Airlines flights
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 9,065 reviews	Search United Airlines flights
Southwest	PriceFrom $284	Free Cancellation	Rating 8.0 4,253 reviews	Search Southwest flights

United Airlines Flights From Indianapolis to San Francisco
United Airlines flight deals from Indianapolis to San Francisco start from $269 round-trip. Over the 4 United Airlines flights for this route in a normal week, average airfare is usually $406 round-trip - but some users have found much cheaper deals with momondo.

Santa Cruz

Carmel-by-the-Sea

Modesto

Sonoma

Bodega Bay

Roseville

Hayward

Calistoga

Big Sur

Santa Clara

Berkeley

Daly City

Walnut Creek

Fremont

Half Moon Bay

Vallejo

Salinas

Livermore

Turlock

Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Finding the right flight to San Francisco from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Indianapolis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Indianapolis to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Indianapolis.

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Indianapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Flights to Atlantafrom $37

Flights to Dallasfrom $53

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Flights to Denverfrom $49

Cheap flights from Indianapolis to San Francisco from $85

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to San Francisco departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Our best United Airlines deals on Indianapolis to San Francisco flight tickets

Frontier flights from Indianapolis to San Francisco

Our best Frontier deals on Indianapolis to San Francisco flight tickets

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Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.

See travel insights to San Francisco from

How to get the cheapest flight ticket from Indianapolis to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $337.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Indianapolis to San Francisco is on a Thursday when prices can be found for as low as $476. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $732.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Indianapolis to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $519. Flights at noon are often more expensive with an average ticket price of $1,075.

What is the cheapest Indianapolis to San Francisco flight route?

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

What cabin class options are available on Indianapolis to San Francisco flights?

There are 4 cabin classes available to choose from on Indianapolis to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Indianapolis to San Francisco flight prices changed over time?

As of December 2025, prices for Indianapolis to San Francisco flights are approximately 20% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Indianapolis to San Francisco?

Alaska Airlines, Southwest, and Frontier are the most popular carriers operating from Indianapolis to San Francisco

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Indianapolis and San Francisco?

Chicago (ORD) was the most common stop: 29% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Indianapolis to San Francisco?

Flights via Dallas (DFW) offer the lowest average round-trip price of $378.

Which layover airport has the shortest travel time from Indianapolis to San Francisco?

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 30m.

Which layover airport has the shortest connection time from Indianapolis to San Francisco?

Dallas (DFW) has the shortest average layover time for this route: 1h 00m.

How many flights depart from Indianapolis to San Francisco on average per day?

The number of flights available between Indianapolis and San Francisco is 2 per day as of December 2025. The most frequent departure time is 6:00PM, with 50% of daily flights leaving at noon.

How many flights depart from Indianapolis to San Francisco on average per week?

As of December 2025, there are 14 flights per week flying from Indianapolis to San Francisco. The most common day of the week flights depart is Mon, with 50% of flights taking off on this day.

When to book flights from Indianapolis to San Francisco

Cheap Indianapolis to San Francisco (IND to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to San Francisco

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

How far is Indianapolis to San Francisco by plane?

When did momondo last update prices for flights from Indianapolis Airport to San Francisco Airport?

How many operators does momondo search for flights from Indianapolis Airport to San Francisco Airport?

How old do you have to be to fly from Indianapolis Airport to San Francisco Airport?

What documentation or ID do you need to fly to San Francisco Airport?

What is the most popular plane model from Indianapolis to San Francisco?

What is the most popular airline from Indianapolis to San Francisco?

Best airlines flying from Indianapolis to San Francisco

Compare and see reviews for airlines that fly from Indianapolis to San Francisco with momondo

United Airlines Flights From Indianapolis to San Francisco

Traveling to a place near San Francisco?

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to San Francisco?

Can I find flights from Indianapolis to San Francisco with flexible booking policies on momondo?

How can momondo help me find flights from Indianapolis to San Francisco?

I’m not ready to book a flight from Indianapolis to San Francisco right now. Can momondo alert me if prices change?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States