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Cheap flights from Indiana to San Diego from $64

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to San Diego departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:00 am - 7:15 pmORD-SAN
14h 15m1 stop
Frontier Logo
6:34 am - 8:43 pmSAN-ORD
12h 09m2 stops
$160Frontier
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Mon, Dec 8 - Thu, Dec 11
United Airlines Logo
7:10 am - 9:39 amORD-SAN
4h 29mnonstop
United Airlines Logo
1:05 pm - 11:10 pmSAN-ORD
8h 05m1 stop
$161United Airlines
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Thu, Nov 27 - Wed, Dec 3
Southwest Logo
5:15 pm - 9:10 pmMDW-SAN
5h 55m1 stop
Southwest Logo
7:00 am - 1:00 pmSAN-MDW
4h 00mnonstop
$162Southwest
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Wed, Dec 3 - Sat, Dec 6
Multiple Airlines Logo
7:51 pm - 12:01 amORD-SAN
6h 10m1 stop
Multiple Airlines Logo
8:00 am - 2:29 pmSAN-ORD
4h 29mnonstop
$162Multiple Airlines
Find Deal
Thu, Feb 5 - Sun, Feb 8
Southwest Logo
8:20 am - 10:50 amMDW-SAN
4h 30mnonstop
Southwest Logo
9:55 am - 7:35 pmSAN-MDW
7h 40m1 stop
$163Southwest
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Wed, Dec 17 - Wed, Dec 31
Alaska Airlines Logo
8:55 am - 11:22 amORD-SAN
4h 27mnonstop
Alaska Airlines Logo
5:53 pm - 11:50 pmSAN-ORD
3h 57mnonstop
$163Alaska Airlines
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Thu, Dec 4 - Tue, Dec 9
Alaska Airlines Logo
8:59 pm - 11:27 pmORD-SAN
4h 28mnonstop
Alaska Airlines Logo
5:31 pm - 11:59 pmSAN-ORD
4h 28mnonstop
$165Alaska Airlines
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Wed, Dec 17 - Sun, Dec 28
Multiple Airlines Logo
3:24 pm - 11:59 pmORD-SAN
10h 35m1 stop
Multiple Airlines Logo
8:00 am - 2:09 pmSAN-ORD
4h 09mnonstop
$168Multiple Airlines
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Fri, Dec 5 - Mon, Dec 8
American Airlines Logo
9:55 am - 12:29 pmORD-SAN
4h 34mnonstop
American Airlines Logo
6:20 am - 12:29 pmSAN-ORD
4h 09mnonstop
$178American Airlines
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Mon, Nov 24 - Wed, Jan 28
American Airlines Logo
6:10 pm - 8:45 pmORD-SAN
4h 35mnonstop
American Airlines Logo
6:15 am - 12:31 pmSAN-ORD
4h 16mnonstop
$187American Airlines
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Thu, Dec 4 - Tue, Dec 9

Frontier flights from Indiana to San Diego

Our best Frontier deals on Indiana to San Diego flight tickets
Frontier
Dec 8
ORD7:00 amChicago O'Hare Intl
14h 15m
1 stop
SAN7:15 pmSan Diego
Dec 11
SAN6:34 amSan Diego
12h 09m
2 stops
ORD8:43 pmChicago O'Hare Intl
$160
Find similar
Frontier
Dec 4
ORD7:00 amChicago O'Hare Intl
18h 59m
1 stop
SAN11:59 pmSan Diego
Dec 9
SAN6:34 amSan Diego
29h 57m
2 stops
ORD2:31 pmChicago O'Hare Intl
$164
Find similar
Frontier
Feb 2
ORD5:20 amChicago O'Hare Intl
20h 41m
2 stops
SAN12:01 amSan Diego
Feb 6
SAN6:25 amSan Diego
10h 21m
1 stop
ORD6:46 pmChicago O'Hare Intl
$170
Find similar

Alaska Airlines flights from Indiana to San Diego

Our best Alaska Airlines deals on Indiana to San Diego flight tickets
Alaska Airlines
Dec 4
ORD8:55 amChicago O'Hare Intl
4h 27m
SAN11:22 amSan Diego
Dec 9
SAN5:53 pmSan Diego
3h 57m
ORD11:50 pmChicago O'Hare Intl
$163
Find similar
Alaska Airlines
Dec 17
ORD8:59 pmChicago O'Hare Intl
4h 28m
SAN11:27 pmSan Diego
Dec 28
SAN5:31 pmSan Diego
4h 28m
ORD11:59 pmChicago O'Hare Intl
$165
Find similar
Alaska Airlines
Nov 27
ORD7:10 amChicago O'Hare Intl
4h 29m
SAN9:39 amSan Diego
Dec 3
SAN5:53 pmSan Diego
3h 57m
ORD11:50 pmChicago O'Hare Intl
$166
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indiana to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Indiana to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Mon 12/8

7:00 am-7:15 pm

1 stop14h 15m

San Diego

Thu 12/11

6:34 am-8:43 pm

2 stops12h 09m

$160

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 11/27

7:10 am-9:39 am

Nonstop4h 29m

San Diego

Wed 12/3

1:05 pm-11:10 pm

1 stop8h 05m

$161

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Wed 12/3

5:15 pm-9:10 pm

1 stop5h 55m

San Diego

Sat 12/6

7:00 am-1:00 pm

Nonstop4h 00m

$162

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 2/5

7:51 pm-12:01 am

1 stop6h 10m

San Diego

Sun 2/8

8:00 am-2:29 pm

Nonstop4h 29m

$162

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Wed 12/17

8:20 am-10:50 am

Nonstop4h 30m

San Diego

Wed 12/31

9:55 am-7:35 pm

1 stop7h 40m

$163

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 12/4

8:55 am-11:22 am

Nonstop4h 27m

San Diego

Tue 12/9

5:53 pm-11:50 pm

Nonstop3h 57m

$163

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 12/17

8:59 pm-11:27 pm

Nonstop4h 28m

San Diego

Sun 12/28

5:31 pm-11:59 pm

Nonstop4h 28m

$165

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Fri 12/5

3:24 pm-11:59 pm

1 stop10h 35m

San Diego

Mon 12/8

8:00 am-2:09 pm

Nonstop4h 09m

$168

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Mon 11/24

9:55 am-12:29 pm

Nonstop4h 34m

San Diego

Wed 1/28

6:20 am-12:29 pm

Nonstop4h 09m

$178

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 12/4

6:10 pm-8:45 pm

Nonstop4h 35m

San Diego

Tue 12/9

6:15 am-12:31 pm

Nonstop4h 16m

$187

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Indiana to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Indiana during the month September is also very affordable. Most momondo users find prices during this month for around $297.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Indiana to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $398. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $562. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $337. Flights at noon are often more expensive with an average ticket price of $567.

What is the cheapest Indiana to San Diego flight route?

Fly from Indianapolis to San Diego for the best Indiana - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $347 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Indiana for as low as $306 on momondo.

What cabin class options are available on Indiana to San Diego flights?

There is only 1 cabin class available to choose from on Indiana to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Indiana to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to San Diego

Best Price Found

$191

Fastest flight time

4h 20m

Direct flights

Every day

Airports in San Diego

1 airport
The best one-way flight to San Diego from Indiana in the past 72 hours is $191. The best round-trip flight deal from Indiana to San Diego found on momondo in the last 72 hours is $351.
The fastest flight from Indiana to San Diego takes 4h 20m
Direct flights go from Indiana to San Diego every day.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • When did momondo last update prices for flights from Indiana to San Diego Airport?

    Prices for flights from Indiana to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Indiana to San Diego Airport?

  • How old do you have to be to fly from Indiana to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Indiana to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Indiana to San Diego?

Best airlines flying from Indiana to San Diego

Compare and see reviews for airlines that fly from Indiana to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $137Free CancellationRating
5.8
3,111 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $138Free CancellationRating
6.3
8,131 reviews
Search Spirit Airlines flights
DeltaPriceFrom $203Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
United AirlinesPriceFrom $226Free CancellationRating
7.4
9,011 reviews
Search United Airlines flights
SouthwestPriceFrom $271Free CancellationRating
8.0
4,238 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Indiana.

Can I find flights from Indiana to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Indiana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Indiana to San Diego?

momondo helps you find the best flight between Indiana and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Indiana to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Indiana are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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