Which layover airport has the shortest connection time from Greenville to San Diego?

Atlanta (ATL) has the shortest average layover time for this route: 1h 00m.

What is the cheapest airline that flies from Greenville to San Diego?

American Airlines, United Airlines, and Southwest are the most popular carriers operating from Greenville to San Diego

What airlines fly to San Diego?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to San Diego from Greenville according to our data. American Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 7 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Greenville to San Diego?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 6h 44m.

Which airport is the most popular layover for flights between Greenville and San Diego?

Charlotte (CLT) was the most common stop: 64% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Greenville to San Diego?

Flights via Detroit (DTW) offer the lowest average round-trip price of $350.

When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

Prices for flights from Greenville Airport to San Diego Airport were last updated today.

How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

There are 4 operators available for flights from Greenville Airport to San Diego Airport as of August 2025.

How old do you have to be to fly from Greenville Airport to San Diego Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$164 Cheap Flights from Greenville to San Diego (GSP-SAN) in 2025

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Greenville to San Diego (GSP-SAN)

Round-trip

One-way

Last minute

Cheap round-trip flights

10:04 am - 3:22 pmGSP-SAN

8h 18m1 stop

10:30 pm - 10:09 amSAN-GSP

8h 39m1 stop

$327Delta

Find Deal

Tue, Oct 28 - Tue, Nov 4

7:41 pm - 11:14 pmGSP-SAN

6h 33m1 stop

10:30 pm - 10:09 amSAN-GSP

8h 39m1 stop

$337Delta

Find Deal

Mon, Oct 27 - Tue, Nov 4

3:05 pm - 6:55 pmGSP-SAN

6h 50m1 stop

5:15 pm - 10:00 amSAN-GSP

13h 45m2 stops

$342Southwest

Find Deal

Thu, Dec 11 - Tue, Dec 16

10:17 am - 2:11 pmGSP-SAN

6h 54m1 stop

12:54 pm - 11:51 pmSAN-GSP

7h 57m1 stop

$347American Airlines

Find Deal

Sat, Oct 4 - Mon, Oct 13

7:41 pm - 11:14 pmGSP-SAN

6h 33m1 stop

10:30 pm - 10:09 amSAN-GSP

8h 39m1 stop

$352Delta

Find Deal

Mon, Oct 27 - Fri, Oct 31

6:33 pm - 10:36 pmGSP-SAN

7h 03m1 stop

10:42 am - 10:30 pmSAN-GSP

8h 48m1 stop

$357American Airlines

Find Deal

Tue, Sep 23 - Fri, Sep 26

7:00 am - 1:40 pmGSP-SAN

9h 40m2 stops

8:39 pm - 11:46 amSAN-GSP

12h 07m2 stops

$367United Airlines

Find Deal

Tue, Sep 23 - Fri, Sep 26

6:05 am - 6:40 pmGSP-SAN

15h 35m2 stops

6:50 am - 7:50 pmSAN-GSP

10h 00m1 stop

$368Southwest

Find Deal

Wed, Oct 29 - Wed, Nov 5

4:59 pm - 9:41 pmGSP-SAN

7h 42m1 stop

6:15 am - 3:46 pmSAN-GSP

6h 31m1 stop

$381United Airlines

Find Deal

Mon, Sep 15 - Thu, Sep 18

5:55 pm - 12:56 pmGSP-SAN

22h 01m2 stops

6:38 pm - 8:58 pmSAN-GSP

23h 20m2 stops

$537Alaska Airlines

Find Deal

Mon, Oct 27 - Mon, Nov 10

American Airlines flights from Greenville to San Diego

Our best American Airlines deals on Greenville to San Diego flight tickets

American Airlines

Oct 4

GSP10:17 amGreenville

6h 54m

1 stop

SAN2:11 pmSan Diego

Oct 13

SAN12:54 pmSan Diego

7h 57m

1 stop

GSP11:51 pmGreenville

$347

Find similar

American Airlines

Sep 23

GSP6:33 pmGreenville

7h 03m

1 stop

SAN10:36 pmSan Diego

Sep 26

SAN10:42 amSan Diego

8h 48m

1 stop

GSP10:30 pmGreenville

$357

Find similar

American Airlines

Oct 10

GSP6:00 amGreenville

8h 26m

1 stop

SAN11:26 amSan Diego

Oct 14

SAN12:30 pmSan Diego

7h 51m

1 stop

GSP11:21 pmGreenville

$377

Find similar

United Airlines flights from Greenville to San Diego

Our best United Airlines deals on Greenville to San Diego flight tickets

United Airlines

Sep 23

GSP7:00 amGreenville

9h 40m

2 stops

SAN1:40 pmSan Diego

Sep 26

SAN8:39 pmSan Diego

12h 07m

2 stops

GSP11:46 amGreenville

$367

Find similar

United Airlines

Sep 15

GSP4:59 pmGreenville

7h 42m

1 stop

SAN9:41 pmSan Diego

Sep 18

SAN6:15 amSan Diego

6h 31m

1 stop

GSP3:46 pmGreenville

$381

Find similar

United Airlines

Sep 25

GSP6:05 amGreenville

9h 52m

1 stop

SAN12:57 pmSan Diego

Sep 28

SAN8:39 pmSan Diego

12h 07m

2 stops

GSP11:46 amGreenville

$414

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 10/28

10:04 am-3:22 pm

1 stop8h 18m

San Diego

Tue 11/4

10:30 pm-10:09 am

1 stop8h 39m

$327

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Mon 10/27

7:41 pm-11:14 pm

1 stop6h 33m

San Diego

Tue 11/4

10:30 pm-10:09 am

1 stop8h 39m

$337

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 12/11

3:05 pm-6:55 pm

1 stop6h 50m

San Diego

Tue 12/16

5:15 pm-10:00 am

2 stops13h 45m

$342

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Sat 10/4

10:17 am-2:11 pm

1 stop6h 54m

San Diego

Mon 10/13

12:54 pm-11:51 pm

1 stop7h 57m

$347

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Mon 10/27

7:41 pm-11:14 pm

1 stop6h 33m

San Diego

Fri 10/31

10:30 pm-10:09 am

1 stop8h 39m

$352

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 9/23

6:33 pm-10:36 pm

1 stop7h 03m

San Diego

Fri 9/26

10:42 am-10:30 pm

1 stop8h 48m

$357

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 9/23

7:00 am-1:40 pm

2 stops9h 40m

San Diego

Fri 9/26

8:39 pm-11:46 am

2 stops12h 07m

$367

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 10/29

6:05 am-6:40 pm

2 stops15h 35m

San Diego

Wed 11/5

6:50 am-7:50 pm

1 stop10h 00m

$368

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Mon 9/15

4:59 pm-9:41 pm

1 stop7h 42m

San Diego

Thu 9/18

6:15 am-3:46 pm

1 stop6h 31m

$381

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Mon 10/27

5:55 pm-12:56 pm

2 stops22h 01m

San Diego

Mon 11/10

6:38 pm-8:58 pm

2 stops23h 20m

$537

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of July, then departing from Greenville during the month February is also very affordable. Most momondo users find prices during this month for around $388.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Greenville to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $487. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $566. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $460. Flights at noon are often more expensive with an average ticket price of $509.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $438 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Greenville for as low as $356 on momondo.

How have Greenville to San Diego flight prices changed over time?

As of August 2025, prices for Greenville to San Diego flights are approximately 16% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Direct flights	None

There are no direct flights from Greenville to San Diego. There are no popular flight routes from Greenville to San Diego.

Search flight deals

How far is Greenville to San Diego by plane?
A flight from Greenville to San Diego will travel around 1990.4 mi. By plane, this route typically takes 5h 57m.
When did momondo last update prices for flights from Greenville Airport to San Diego Airport?
Prices for flights from Greenville Airport to San Diego Airport were last updated today.
How many operators does momondo search for flights from Greenville Airport to San Diego Airport?
There are 4 operators available for flights from Greenville Airport to San Diego Airport as of August 2025.
How old do you have to be to fly from Greenville Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Greenville to San Diego?
momondo data reveals that the most frequently booked airline on the route from Greenville to San Diego is American Airlines, representing 65% of all bookings. The subsequent popular airlines are Delta at 21%, Southwest at 8%, and United Airlines at 7%.

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $284	Free Cancellation	Rating 7.9 7,979 reviews	Search Delta flights
American Airlines	PriceFrom $301	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southwest	PriceFrom $350	Free Cancellation	Rating 8.0 4,243 reviews	Search Southwest flights
United Airlines	PriceFrom $373	Free Cancellation	Rating 7.4 8,943 reviews	Search United Airlines flights

Coronado

Chula Vista

El Cajon

Julian

La Mesa

National City

Imperial Beach

Poway

San Ysidro

Borrego Springs

Alpine

Lemon Grove

Santee

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Finding the right flight to San Diego from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Greenville.

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Greenville and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sun 8/31

Sun 9/7

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Airports servicing California

Popular cities in the United States

Flights to New Yorkfrom $35

Flights to Los Angelesfrom $37

Flights to Miamifrom $39

Flights to Chicagofrom $37

Flights to Orlandofrom $37

Flights to Las Vegasfrom $37

Flights to San Franciscofrom $37

Flights to Washington, D.C.from $37

Flights to Bostonfrom $58

Flights to Atlantafrom $39

Flights to Dallasfrom $45

Flights to Seattlefrom $53

Cheap flights from Greenville to San Diego from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Diego departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Greenville to San Diego (GSP-SAN)

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

American Airlines flights from Greenville to San Diego

Our best American Airlines deals on Greenville to San Diego flight tickets

United Airlines flights from Greenville to San Diego

Our best United Airlines deals on Greenville to San Diego flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

See travel insights to San Diego from

How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of July, then departing from Greenville during the month February is also very affordable. Most momondo users find prices during this month for around $388.

What is the cheapest day to depart on your flight to San Diego?

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $460. Flights at noon are often more expensive with an average ticket price of $509.

How far in advance should I book a flight to San Diego?

How have Greenville to San Diego flight prices changed over time?

As of August 2025, prices for Greenville to San Diego flights are approximately 16% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Greenville to San Diego?

American Airlines, United Airlines, and Southwest are the most popular carriers operating from Greenville to San Diego

What airlines fly to San Diego?

Which airport is the most popular layover for flights between Greenville and San Diego?

Charlotte (CLT) was the most common stop: 64% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Greenville to San Diego?

Flights via Detroit (DTW) offer the lowest average round-trip price of $350.

Which layover airport has the shortest travel time from Greenville to San Diego?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 6h 44m.

Which layover airport has the shortest connection time from Greenville to San Diego?

Atlanta (ATL) has the shortest average layover time for this route: 1h 00m.

When to book flights from Greenville to San Diego

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Direct flights

How far is Greenville to San Diego by plane?

When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

How old do you have to be to fly from Greenville Airport to San Diego Airport?

What documentation or ID do you need to fly to San Diego Airport?

What is the most popular airline from Greenville to San Diego?

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo

Traveling to a place near San Diego?

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

How can momondo help me find flights from Greenville to San Diego?

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California