What airlines fly to San Diego?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to San Diego from Greenville according to our data. American Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 7 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Greenville to San Diego?

Atlanta (ATL) has the shortest average layover time for this route: 1h 13m.

What is the cheapest airline that flies from Greenville to San Diego?

Breeze Airways, American Airlines, and United Airlines are the most popular carriers operating from Greenville to San Diego

Which layover airport has the shortest travel time from Greenville to San Diego?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 6h 36m.

Which airport is the most popular layover for flights between Greenville and San Diego?

Charlotte (CLT) was the most common stop: 58% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Greenville to San Diego?

Flights via Detroit (DTW) offer the lowest average round-trip price of $350.

When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

Prices for flights from Greenville Airport to San Diego Airport were last updated today.

How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

There are 4 operators available for flights from Greenville Airport to San Diego Airport as of October 2025.

How old do you have to be to fly from Greenville Airport to San Diego Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$141 Cheap Flights from Greenville to San Diego in 2025/26

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4:24 pm - 10:17 pmGSP-SAN

8h 53m1 stop

6:19 am - 8:00 pmSAN-GSP

10h 41m1 stop

$339American Airlines

Find Deal

jue., nov. 13 - mar., nov. 18

4:24 pm - 8:18 pmGSP-SAN

6h 54m1 stop

6:19 am - 8:00 pmSAN-GSP

10h 41m1 stop

$348American Airlines

Find Deal

jue., nov. 13 - mar., nov. 18

6:00 am - 12:33 pmGSP-SAN

9h 33m1 stop

6:19 am - 8:00 pmSAN-GSP

10h 41m1 stop

$350American Airlines

Find Deal

mié., nov. 5 - mié., nov. 12

11:29 am - 6:00 pmGSP-SAN

9h 31m1 stop

10:00 pm - 11:02 amSAN-GSP

10h 02m1 stop

$359Delta

Find Deal

jue., nov. 6 - lun., nov. 10

3:05 pm - 6:55 pmGSP-SAN

6h 50m1 stop

6:40 pm - 10:00 amSAN-GSP

12h 20m2 stops

$364Southwest

Find Deal

mié., dic. 10 - mar., dic. 16

6:00 am - 12:45 pmGSP-SAN

9h 45m1 stop

6:20 am - 4:25 pmSAN-GSP

7h 05m1 stop

$366American Airlines

Find Deal

vie., nov. 21 - jue., nov. 27

3:05 pm - 9:10 pmGSP-SAN

9h 05m2 stops

7:30 pm - 10:00 amSAN-GSP

11h 30m2 stops

$369Southwest

Find Deal

mié., dic. 10 - mar., dic. 16

7:27 am - 2:15 pmGSP-SAN

9h 48m1 stop

9:50 pm - 9:02 amSAN-GSP

8h 12m1 stop

$372Delta

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jue., nov. 27 - lun., dic. 1

9:10 am - 4:02 pmGSP-SAN

9h 52m1 stop

8:40 pm - 11:47 amSAN-GSP

12h 07m2 stops

$444United Airlines

Find Deal

jue., nov. 6 - dom., nov. 9

4:17 pm - 11:44 pmGSP-SAN

10h 27m2 stops

8:40 pm - 11:47 amSAN-GSP

12h 07m2 stops

$447United Airlines

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mié., nov. 12 - dom., nov. 16

Southwest flights from Greenville to San Diego

Our best Southwest deals on Greenville to San Diego flight tickets

Southwest

Dec 10

GSP3:05 pmGreenville

6h 50m

1 stop

SAN6:55 pmSan Diego

Dec 16

SAN6:40 pmSan Diego

12h 20m

2 stops

GSP10:00 amGreenville

$364

Find similar

Southwest

Dec 10

GSP3:05 pmGreenville

9h 05m

2 stops

SAN9:10 pmSan Diego

Dec 16

SAN7:30 pmSan Diego

11h 30m

2 stops

GSP10:00 amGreenville

$369

Find similar

Southwest

Nov 12

GSP10:35 amGreenville

7h 45m

1 stop

SAN3:20 pmSan Diego

Nov 16

SAN6:35 amSan Diego

6h 05m

1 stop

GSP3:40 pmGreenville

$403

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United Airlines flights from Greenville to San Diego

Our best United Airlines deals on Greenville to San Diego flight tickets

United Airlines

Nov 6

GSP9:10 amGreenville

9h 52m

1 stop

SAN4:02 pmSan Diego

Nov 9

SAN8:40 pmSan Diego

12h 07m

2 stops

GSP11:47 amGreenville

$444

Find similar

United Airlines

Nov 12

GSP4:17 pmGreenville

10h 27m

2 stops

SAN11:44 pmSan Diego

Nov 16

SAN8:40 pmSan Diego

12h 07m

2 stops

GSP11:47 amGreenville

$447

Find similar

United Airlines

Nov 27

GSP2:55 pmGreenville

8h 38m

1 stop

SAN8:33 pmSan Diego

Dec 1

SAN8:40 pmSan Diego

12h 04m

2 stops

GSP11:44 amGreenville

$462

Find similar

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

jue. 11/13

4:24 pm-10:17 pm

1 stop8h 53m

San Diego

mar. 11/18

6:19 am-8:00 pm

1 stop10h 41m

$339

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

jue. 11/13

4:24 pm-8:18 pm

1 stop6h 54m

San Diego

mar. 11/18

6:19 am-8:00 pm

1 stop10h 41m

$348

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

mié. 11/5

6:00 am-12:33 pm

1 stop9h 33m

San Diego

mié. 11/12

6:19 am-8:00 pm

1 stop10h 41m

$350

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

jue. 11/6

11:29 am-6:00 pm

1 stop9h 31m

San Diego

lun. 11/10

10:00 pm-11:02 am

1 stop10h 02m

$359

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

mié. 12/10

3:05 pm-6:55 pm

1 stop6h 50m

San Diego

mar. 12/16

6:40 pm-10:00 am

2 stops12h 20m

$364

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

vie. 11/21

6:00 am-12:45 pm

1 stop9h 45m

San Diego

jue. 11/27

6:20 am-4:25 pm

1 stop7h 05m

$366

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

mié. 12/10

3:05 pm-9:10 pm

2 stops9h 05m

San Diego

mar. 12/16

7:30 pm-10:00 am

2 stops11h 30m

$369

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

jue. 11/27

7:27 am-2:15 pm

1 stop9h 48m

San Diego

lun. 12/1

9:50 pm-9:02 am

1 stop8h 12m

$372

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

jue. 11/6

9:10 am-4:02 pm

1 stop9h 52m

San Diego

dom. 11/9

8:40 pm-11:47 am

2 stops12h 07m

$444

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

mié. 11/12

4:17 pm-11:44 pm

2 stops10h 27m

San Diego

dom. 11/16

8:40 pm-11:47 am

2 stops12h 07m

$447

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of July, then departing from Greenville during the month February is also very affordable. Most momondo users find prices during this month for around $384.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Greenville to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $487. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $566. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $460. Flights at noon are often more expensive with an average ticket price of $509.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Greenville for as low as $356 on momondo.

How have Greenville to San Diego flight prices changed over time?

As of October 2025, prices for Greenville to San Diego flights are approximately 48% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Direct flights	None

There are no direct flights from Greenville to San Diego. There are no popular flight routes from Greenville to San Diego.

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How far is Greenville to San Diego by plane?
A flight from Greenville to San Diego will travel around 1990.4 mi. By plane, this route typically takes 6h 44m.
When did momondo last update prices for flights from Greenville Airport to San Diego Airport?
Prices for flights from Greenville Airport to San Diego Airport were last updated today.
How many operators does momondo search for flights from Greenville Airport to San Diego Airport?
There are 4 operators available for flights from Greenville Airport to San Diego Airport as of October 2025.
How old do you have to be to fly from Greenville Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Greenville to San Diego?
momondo data reveals that the most frequently booked airline on the route from Greenville to San Diego is American Airlines, representing 62% of all bookings. The subsequent popular airlines are Delta at 23%, United Airlines at 8%, and Southwest at 7%.

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $284	Free Cancellation	Rating 7.9 7,984 reviews	Search Delta flights
American Airlines	PriceFrom $291	Free Cancellation	Rating 7.2 11,043 reviews	Search American Airlines flights
United Airlines	PriceFrom $312	Free Cancellation	Rating 7.4 8,982 reviews	Search United Airlines flights
Southwest	PriceFrom $350	Free Cancellation	Rating 8.0 4,241 reviews	Search Southwest flights

Coronado

Chula Vista

El Cajon

Julian

National City

La Mesa

Imperial Beach

Poway

San Ysidro

Borrego Springs

Lemon Grove

Alpine

Santee

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Finding the right flight to San Diego from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Greenville.

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Greenville and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Greenville to San Diego from $141

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Diego departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of July, then departing from Greenville during the month February is also very affordable. Most momondo users find prices during this month for around $384.

What is the cheapest day to depart on your flight to San Diego?

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $460. Flights at noon are often more expensive with an average ticket price of $509.

How far in advance should I book a flight to San Diego?

How have Greenville to San Diego flight prices changed over time?

As of October 2025, prices for Greenville to San Diego flights are approximately 48% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Greenville to San Diego?

Breeze Airways, American Airlines, and United Airlines are the most popular carriers operating from Greenville to San Diego

What airlines fly to San Diego?

Which airport is the most popular layover for flights between Greenville and San Diego?

Charlotte (CLT) was the most common stop: 58% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Greenville to San Diego?

Flights via Detroit (DTW) offer the lowest average round-trip price of $350.

Which layover airport has the shortest travel time from Greenville to San Diego?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 6h 36m.

Which layover airport has the shortest connection time from Greenville to San Diego?

Atlanta (ATL) has the shortest average layover time for this route: 1h 13m.

When to book flights from Greenville to San Diego

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Direct flights

How far is Greenville to San Diego by plane?

When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

How old do you have to be to fly from Greenville Airport to San Diego Airport?

What documentation or ID do you need to fly to San Diego Airport?

What is the most popular airline from Greenville to San Diego?

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo

Traveling to a place near San Diego?

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

How can momondo help me find flights from Greenville to San Diego?

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California