Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Greenville to San Diego from $140

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Diego departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Greenville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:50 pm - 11:25 pm
GSP
-
SAN
8h 35m
1 stop
Delta Logo
11:02 am - 10:13 pm
SAN
-
GSP
8h 11m
1 stop
$367Delta
Wed, Apr 22 - Tue, Apr 28
United Airlines Logo
7:00 am - 11:04 am
GSP
-
SAN
7h 04m
1 stop
United Airlines Logo
10:30 pm - 9:59 am
SAN
-
GSP
8h 29m
1 stop
$372United Airlines
Sat, Apr 25 - Wed, Apr 29
Delta Logo
7:30 am - 2:20 pm
GSP
-
SAN
9h 50m
1 stop
Delta Logo
10:30 pm - 10:20 am
SAN
-
GSP
8h 50m
1 stop
$377Delta
Sat, Apr 25 - Sat, May 2
Delta Logo
5:21 pm - 11:25 pm
GSP
-
SAN
9h 04m
1 stop
Delta Logo
6:15 am - 5:40 pm
SAN
-
GSP
8h 25m
1 stop
$380Delta
Thu, Apr 23 - Wed, Apr 29
Southwest Logo
10:45 am - 5:55 pm
GSP
-
SAN
10h 10m
2 stops
Southwest Logo
10:20 am - 9:40 pm
SAN
-
GSP
8h 20m
2 stops
$382Southwest
Sat, Apr 25 - Wed, Apr 29
Delta Logo
8:45 am - 12:50 pm
GSP
-
SAN
7h 05m
1 stop
Delta Logo
10:30 pm - 9:02 am
SAN
-
GSP
7h 32m
1 stop
$385Delta
Sat, May 9 - Mon, May 11
Southwest Logo
6:20 am - 12:45 pm
GSP
-
SAN
9h 25m
2 stops
Southwest Logo
1:50 pm - 10:45 pm
SAN
-
GSP
5h 55m
1 stop
$390Southwest
Tue, Mar 31 - Sat, Apr 4
United Airlines Logo
4:55 pm - 11:40 pm
GSP
-
SAN
9h 45m
2 stops
United Airlines Logo
9:45 pm - 9:58 am
SAN
-
GSP
9h 13m
1 stop
$391United Airlines
Wed, Mar 25 - Thu, Apr 2
Delta Logo
6:26 pm - 11:06 pm
GSP
-
SAN
7h 40m
1 stop
Delta Logo
10:15 pm - 10:54 am
SAN
-
GSP
9h 39m
1 stop
$393Delta
Mon, May 4 - Mon, May 11
Southwest Logo
6:25 am - 10:20 am
GSP
-
SAN
6h 55m
1 stop
Southwest Logo
10:40 pm - 11:45 am
SAN
-
GSP
10h 05m
1 stop
$398Southwest
Mon, Mar 30 - Thu, Apr 2

Delta flights from Greenville to San Diego

Our best Delta deals on Greenville to San Diego flight tickets
Delta
Apr 22
GSP5:50 pmGreenville
8h 35m
1 stop
SAN11:25 pmSan Diego
Apr 28
SAN11:02 amSan Diego
8h 11m
1 stop
GSP10:13 pmGreenville
$367
Delta
Apr 25
GSP7:30 amGreenville
9h 50m
1 stop
SAN2:20 pmSan Diego
May 2
SAN10:30 pmSan Diego
8h 50m
1 stop
GSP10:20 amGreenville
$377
Delta
Apr 23
GSP5:21 pmGreenville
9h 04m
1 stop
SAN11:25 pmSan Diego
Apr 29
SAN6:15 amSan Diego
8h 25m
1 stop
GSP5:40 pmGreenville
$380

United Airlines flights from Greenville to San Diego

Our best United Airlines deals on Greenville to San Diego flight tickets
United Airlines
Apr 25
GSP7:00 amGreenville
7h 04m
1 stop
SAN11:04 amSan Diego
Apr 29
SAN10:30 pmSan Diego
8h 29m
1 stop
GSP9:59 amGreenville
$372
United Airlines
Mar 25
GSP4:55 pmGreenville
9h 45m
2 stops
SAN11:40 pmSan Diego
Apr 2
SAN9:45 pmSan Diego
9h 13m
1 stop
GSP9:58 amGreenville
$391
United Airlines
May 27
GSP4:55 pmGreenville
10h 04m
2 stops
SAN11:59 pmSan Diego
Jun 2
SAN11:58 amSan Diego
7h 13m
1 stop
GSP10:11 pmGreenville
$452

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 4/22

5:50 pm-11:25 pm

1 stop8h 35m

San Diego

Tue 4/28

11:02 am-10:13 pm

1 stop8h 11m

$367

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Sat 4/25

7:00 am-11:04 am

1 stop7h 04m

San Diego

Wed 4/29

10:30 pm-9:59 am

1 stop8h 29m

$372

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Sat 4/25

7:30 am-2:20 pm

1 stop9h 50m

San Diego

Sat 5/2

10:30 pm-10:20 am

1 stop8h 50m

$377

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 4/23

5:21 pm-11:25 pm

1 stop9h 04m

San Diego

Wed 4/29

6:15 am-5:40 pm

1 stop8h 25m

$380

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Sat 4/25

10:45 am-5:55 pm

2 stops10h 10m

San Diego

Wed 4/29

10:20 am-9:40 pm

2 stops8h 20m

$382

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Sat 5/9

8:45 am-12:50 pm

1 stop7h 05m

San Diego

Mon 5/11

10:30 pm-9:02 am

1 stop7h 32m

$385

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 3/31

6:20 am-12:45 pm

2 stops9h 25m

San Diego

Sat 4/4

1:50 pm-10:45 pm

1 stop5h 55m

$390

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 3/25

4:55 pm-11:40 pm

2 stops9h 45m

San Diego

Thu 4/2

9:45 pm-9:58 am

1 stop9h 13m

$391

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Mon 5/4

6:26 pm-11:06 pm

1 stop7h 40m

San Diego

Mon 5/11

10:15 pm-10:54 am

1 stop9h 39m

$393

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Mon 3/30

6:25 am-10:20 am

1 stop6h 55m

San Diego

Thu 4/2

10:40 pm-11:45 am

1 stop10h 05m

$398

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of July, then departing from Greenville during the month January is also very affordable. Most momondo users find prices during this month for around $367.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $425 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Greenville for as low as $346 on momondo.

How have Greenville to San Diego flight prices changed over time?

As of February 2026, prices for Greenville to San Diego flights are approximately 3% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Fastest flight time

7h 26m

Direct flights

None
The fastest flight from Greenville to San Diego takes 7h 26m
There are no direct flights from Greenville to San Diego. There are no popular flight routes from Greenville to San Diego.
Search flight deals

  • How far is Greenville to San Diego by plane?

    A flight from Greenville to San Diego will travel around 1990.4 mi. By plane, this route typically takes 7h 26m.

  • When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

    Prices for flights from Greenville Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

  • How old do you have to be to fly from Greenville Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Diego?

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $148Free CancellationRating
7.9
8,203 reviews
Search Delta flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,288 reviews
Search American Airlines flights
United AirlinesPriceFrom $312Free CancellationRating
7.4
9,289 reviews
Search United Airlines flights
SouthwestPriceFrom $356Free CancellationRating
8.0
4,284 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Finding the right flight to San Diego from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Greenville.

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Greenville and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 3/16
Mon 3/23
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States