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Cheap flights from Greenville to San Diego from $139

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:37 pm - 10:40 pmGSP  Greenville-SAN San Diego
8h 03m1 stop Chicago O'Hare Intl
United Airlines Logo
10:40 am - 11:18 pmSAN  San Diego-GSP Greenville
9h 38m1 stop Chicago O'Hare Intl
$277United Airlines
Tue, Nov 10 - Tue, Nov 17
United Airlines Logo
6:30 am - 11:22 amGSP  Greenville-SAN San Diego
7h 52m1 stop Chicago O'Hare Intl
United Airlines Logo
10:30 pm - 9:56 amSAN  San Diego-GSP Greenville
8h 26m1 stop Chicago O'Hare Intl
$277United Airlines
Wed, Jan 27 - Wed, Jan 27
American Airlines Logo
7:46 pm - 11:55 pmGSP  Greenville-SAN San Diego
7h 09m1 stop Dallas/Fort Worth
American Airlines Logo
10:27 pm - 9:37 amSAN  San Diego-GSP Greenville
8h 10m1 stop Charlotte Douglas
$277American Airlines
Thu, Sep 24 - Mon, Sep 28
American Airlines Logo
5:28 pm - 9:03 pmGSP  Greenville-SAN San Diego
6h 35m1 stop Dallas/Fort Worth
American Airlines Logo
6:15 am - 4:34 pmSAN  San Diego-GSP Greenville
7h 19m1 stop Dallas/Fort Worth
$277American Airlines
Tue, Sep 8 - Tue, Sep 15
Southwest Logo
5:30 pm - 8:50 pmGSP  Greenville-SAN San Diego
6h 20m1 stop Nashville Intl
Southwest Logo
10:40 pm - 10:15 amSAN  San Diego-GSP Greenville
8h 35m1 stop Baltimore/Washington
$277Southwest
Tue, Sep 15 - Mon, Sep 21
Southwest Logo
8:40 pm - 12:30 amGSP  Greenville-SAN San Diego
6h 50m1 stop Nashville Intl
Southwest Logo
9:50 pm - 10:05 amSAN  San Diego-GSP Greenville
9h 15m1 stop Baltimore/Washington
$277Southwest
Thu, Oct 22 - Mon, Oct 26
Delta Logo
7:00 am - 2:29 pmGSP  Greenville-SAN San Diego
10h 29m1 stop Detroit Metropolitan Wayne County
Delta Logo
11:39 am - 9:49 pmSAN  San Diego-GSP Greenville
7h 10m1 stop Detroit Metropolitan Wayne County
$297Delta
Thu, Nov 26 - Thu, Dec 3
Delta Logo
5:30 am - 11:31 amGSP  Greenville-SAN San Diego
9h 01m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:30 pm - 9:47 amSAN  San Diego-GSP Greenville
8h 17m1 stop Atlanta Hartsfield-Jackson
$297Delta
Thu, Nov 12 - Mon, Nov 16
Alaska Airlines Logo
11:42 am - 11:46 pmGSP  Greenville-SAN San Diego
15h 04m2 stops Chicago O'Hare Intl Seattle/Tacoma Intl
Alaska Airlines Logo
7:00 am - 9:58 pmSAN  San Diego-GSP Greenville
11h 58m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
$673Alaska Airlines
Sat, Nov 21 - Wed, Dec 2
Alaska Airlines Logo
4:38 pm - 10:52 pmGSP  Greenville-SAN San Diego
9h 14m1 stop Chicago O'Hare Intl
Alaska Airlines Logo
6:15 am - 9:57 pmSAN  San Diego-GSP Greenville
12h 42m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
$717Alaska Airlines
Wed, Nov 25 - Fri, Nov 27

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United Airlines flights from Greenville to San Diego

Our best United Airlines deals on Greenville to San Diego flight tickets
United Airlines
Sep 2
GSP7:00 amGreenville
8h 50m
1 stop
SAN12:50 pmSan Diego
Sep 6
SAN10:40 pmSan Diego
7h 56m
1 stop
GSP9:36 amGreenville
$389
United Airlines
Sep 23
GSP6:20 amGreenville
14h 06m
2 stops
SAN5:26 pmSan Diego
Sep 29
SAN10:20 pmSan Diego
9h 25m
1 stop
GSP10:45 amGreenville
$392
United Airlines
Sep 2
GSP10:33 amGreenville
9h 27m
2 stops
SAN5:00 pmSan Diego
Sep 6
SAN10:40 pmSan Diego
7h 56m
1 stop
GSP9:36 amGreenville
$394

Southwest flights from Greenville to San Diego

Our best Southwest deals on Greenville to San Diego flight tickets
Southwest
Oct 7
GSP7:20 pmGreenville
6h 45m
1 stop
SAN11:05 pmSan Diego
Oct 13
SAN10:40 pmSan Diego
11h 00m
1 stop
GSP12:40 pmGreenville
$282
Southwest
Nov 10
GSP11:20 amGreenville
8h 20m
2 stops
SAN4:40 pmSan Diego
Nov 17
SAN8:15 amSan Diego
9h 30m
2 stops
GSP8:45 pmGreenville
$287
Southwest
Oct 1
GSP8:40 pmGreenville
6h 50m
1 stop
SAN12:30 amSan Diego
Oct 3
SAN9:50 pmSan Diego
8h 55m
1 stop
GSP9:45 amGreenville
$318

momondo Fare Finder

 
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Tue 11/10

5:37 pm-10:40 pm

1 stop8h 03m

San Diego

Tue 11/17

10:40 am-11:18 pm

1 stop9h 38m

$277

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Wed 1/27

6:30 am-11:22 am

1 stop7h 52m

San Diego

Wed 1/27

10:30 pm-9:56 am

1 stop8h 26m

$277

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Thu 9/24

7:46 pm-11:55 pm

1 stop7h 09m

San Diego

Mon 9/28

10:27 pm-9:37 am

1 stop8h 10m

$277
Quickest round-trip

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Tue 9/8

5:28 pm-9:03 pm

1 stop6h 35m

San Diego

Tue 9/15

6:15 am-4:34 pm

1 stop7h 19m

$277

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Tue 9/15

5:30 pm-8:50 pm

1 stop6h 20m

San Diego

Mon 9/21

10:40 pm-10:15 am

1 stop8h 35m

$277

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Thu 10/22

8:40 pm-12:30 am

1 stop6h 50m

San Diego

Mon 10/26

9:50 pm-10:05 am

1 stop9h 15m

$277

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Thu 11/26

7:00 am-2:29 pm

1 stop10h 29m

San Diego

Thu 12/3

11:39 am-9:49 pm

1 stop7h 10m

$297

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Thu 11/12

5:30 am-11:31 am

1 stop9h 01m

San Diego

Mon 11/16

10:30 pm-9:47 am

1 stop8h 17m

$297

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Sat 11/21

11:42 am-11:46 pm

2 stops15h 04m

San Diego

Wed 12/2

7:00 am-9:58 pm

2 stops11h 58m

$673

GreenvilleSan Diego

GSP Greenville - SAN San Diego

GSPSAN

Greenville

Wed 11/25

4:38 pm-10:52 pm

1 stop9h 14m

San Diego

Fri 11/27

6:15 am-9:57 pm

2 stops12h 42m

$717

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $341 to $546.
The lowest price recently found on this route was $277.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Greenville during the month January is also very affordable. Most momondo users find prices during this month for around $367.

How far in advance should I book a flight from Greenville to San Diego?

You are more likely to see cheaper flights to San Diego from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $493 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Greenville for as low as $299 on momondo.

How have Greenville to San Diego flight prices changed over time?

As of August 2026, prices for Greenville to San Diego flights are approximately 17% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Best Price Found

$139

Fastest flight time

6h 42m

Direct flights

None
The best one-way flight to San Diego from Greenville in the past 72 hours is $139. The best round-trip flight deal from Greenville to San Diego found on momondo in the last 72 hours is $277.
The fastest flight from Greenville to San Diego takes 6h 42m
There are no direct flights from Greenville to San Diego. There are no popular flight routes from Greenville to San Diego.
Search flight deals

Frequently asked questions about flying from Greenville to San Diego

  • How far is Greenville to San Diego by plane?

    A flight from Greenville to San Diego will travel around 1990.4 mi. By plane, this route typically takes 6h 42m.

  • When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

    Prices for flights from Greenville Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

  • How old do you have to be to fly from Greenville Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Diego?

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $298Free CancellationRating
7.8
8,513 reviews
Search Delta flights
SouthwestPriceFrom $305Free CancellationRating
8.0
4,215 reviews
Search Southwest flights
United AirlinesPriceFrom $312Free CancellationRating
7.4
10,105 reviews
Search United Airlines flights
American AirlinesPriceFrom $312Free CancellationRating
7.1
11,979 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
National City
Julian
La Mesa
Poway
San Ysidro
Imperial Beach
Santee
Borrego Springs
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Finding the right flight to San Diego from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Greenville.

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Greenville and alert you when they change.

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