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Cheap flights from Greenville to San Diego from $183

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Diego departing on 7/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:30 pm - 8:45 pm
GSP
-
SAN
6h 15m
1 stop
Southwest Logo
10:40 pm - 10:15 am
SAN
-
GSP
8h 35m
1 stop
$261Southwest
Wed, Aug 12 - Tue, Aug 18
Southwest Logo
5:30 pm - 8:45 pm
GSP
-
SAN
6h 15m
1 stop
Southwest Logo
8:35 am - 8:55 pm
SAN
-
GSP
9h 20m
2 stops
$266Southwest
Wed, Aug 12 - Tue, Aug 18
Southwest Logo
6:55 pm - 11:25 pm
GSP
-
SAN
7h 30m
1 stop
Southwest Logo
8:35 am - 8:55 pm
SAN
-
GSP
9h 20m
2 stops
$286Southwest
Thu, Aug 13 - Tue, Aug 18
Southwest Logo
6:55 pm - 11:25 pm
GSP
-
SAN
7h 30m
1 stop
Southwest Logo
10:40 pm - 10:15 am
SAN
-
GSP
8h 35m
1 stop
$300Southwest
Thu, Aug 13 - Mon, Aug 17
American Airlines Logo
5:28 pm - 11:59 pm
GSP
-
SAN
9h 31m
1 stop
American Airlines Logo
6:20 am - 4:38 pm
SAN
-
GSP
7h 18m
1 stop
$311American Airlines
Thu, Aug 13 - Mon, Aug 17
Southwest Logo
2:10 pm - 7:15 pm
GSP
-
SAN
8h 05m
1 stop
Southwest Logo
6:50 am - 6:30 pm
SAN
-
GSP
8h 40m
1 stop
$322Southwest
Fri, Oct 2 - Wed, Oct 7
Southwest Logo
2:10 pm - 7:15 pm
GSP
-
SAN
8h 05m
1 stop
Southwest Logo
9:35 am - 9:00 pm
SAN
-
GSP
8h 25m
2 stops
$328Southwest
Fri, Oct 2 - Wed, Oct 7
Delta Logo
6:00 am - 9:26 am
GSP
-
SAN
6h 26m
1 stop
Delta Logo
10:25 pm - 9:25 am
SAN
-
GSP
8h 00m
1 stop
$333Delta
Tue, Sep 1 - Tue, Sep 8
Southwest Logo
1:20 pm - 7:35 pm
GSP
-
SAN
9h 15m
1 stop
Southwest Logo
8:35 am - 8:55 pm
SAN
-
GSP
9h 20m
2 stops
$338Southwest
Wed, Sep 2 - Tue, Sep 8
Southwest Logo
11:00 am - 4:55 pm
GSP
-
SAN
8h 55m
2 stops
Southwest Logo
8:35 am - 8:55 pm
SAN
-
GSP
9h 20m
2 stops
$341Southwest
Wed, Aug 12 - Tue, Aug 18

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United Airlines flights from Greenville to San Diego

Our best United Airlines deals on Greenville to San Diego flight tickets
United Airlines
Aug 31
GSP3:01 pmGreenville
8h 28m
1 stop
SAN8:29 pmSan Diego
Sep 5
SAN9:45 pmSan Diego
9h 52m
2 stops
GSP10:37 amGreenville
$364
United Airlines
Sep 1
GSP5:43 pmGreenville
7h 27m
1 stop
SAN10:10 pmSan Diego
Sep 5
SAN6:18 amSan Diego
7h 44m
1 stop
GSP5:02 pmGreenville
$443
United Airlines
Sep 26
GSP2:16 pmGreenville
9h 23m
2 stops
SAN8:39 pmSan Diego
Sep 30
SAN10:30 pmSan Diego
8h 28m
1 stop
GSP9:58 amGreenville
$448

Delta flights from Greenville to San Diego

Our best Delta deals on Greenville to San Diego flight tickets
Delta
Sep 1
GSP6:00 amGreenville
6h 26m
1 stop
SAN9:26 amSan Diego
Sep 8
SAN10:25 pmSan Diego
8h 00m
1 stop
GSP9:25 amGreenville
$333
Delta
Aug 31
GSP8:49 amGreenville
6h 44m
1 stop
SAN12:33 pmSan Diego
Sep 8
SAN10:25 pmSan Diego
8h 00m
1 stop
GSP9:25 amGreenville
$346
Delta
Aug 31
GSP11:10 amGreenville
10h 04m
1 stop
SAN6:14 pmSan Diego
Sep 10
SAN6:20 amSan Diego
8h 00m
1 stop
GSP5:20 pmGreenville
$359

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 8/12

5:30 pm-8:45 pm

1 stop6h 15m

San Diego

Tue 8/18

10:40 pm-10:15 am

1 stop8h 35m

$261

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 8/12

5:30 pm-8:45 pm

1 stop6h 15m

San Diego

Tue 8/18

8:35 am-8:55 pm

2 stops9h 20m

$266

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 8/13

6:55 pm-11:25 pm

1 stop7h 30m

San Diego

Tue 8/18

8:35 am-8:55 pm

2 stops9h 20m

$286

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 8/13

6:55 pm-11:25 pm

1 stop7h 30m

San Diego

Mon 8/17

10:40 pm-10:15 am

1 stop8h 35m

$300

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 8/13

5:28 pm-11:59 pm

1 stop9h 31m

San Diego

Mon 8/17

6:20 am-4:38 pm

1 stop7h 18m

$311

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Fri 10/2

2:10 pm-7:15 pm

1 stop8h 05m

San Diego

Wed 10/7

6:50 am-6:30 pm

1 stop8h 40m

$322

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Fri 10/2

2:10 pm-7:15 pm

1 stop8h 05m

San Diego

Wed 10/7

9:35 am-9:00 pm

2 stops8h 25m

$328
Quickest round-trip

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 9/1

6:00 am-9:26 am

1 stop6h 26m

San Diego

Tue 9/8

10:25 pm-9:25 am

1 stop8h 00m

$333

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 9/2

1:20 pm-7:35 pm

1 stop9h 15m

San Diego

Tue 9/8

8:35 am-8:55 pm

2 stops9h 20m

$338

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Wed 8/12

11:00 am-4:55 pm

2 stops8h 55m

San Diego

Tue 8/18

8:35 am-8:55 pm

2 stops9h 20m

$341

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Greenville to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from Greenville during the month August is also very affordable. Most momondo users find prices during this month for around $394.

How far in advance should I book a flight from Greenville to San Diego?

You are more likely to see cheaper flights to San Diego from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $483 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Greenville for as low as $299 on momondo.

How have Greenville to San Diego flight prices changed over time?

As of July 2026, prices for Greenville to San Diego flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Diego (GSP to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Diego

Fastest flight time

6h 15m

Direct flights

None
The fastest flight from Greenville to San Diego takes 6h 15m
There are no direct flights from Greenville to San Diego. There are no popular flight routes from Greenville to San Diego.
Search flight deals

Frequently asked questions about flying from Greenville to San Diego

  • How far is Greenville to San Diego by plane?

    A flight from Greenville to San Diego will travel around 1990.4 mi. By plane, this route typically takes 6h 15m.

  • When did momondo last update prices for flights from Greenville Airport to San Diego Airport?

    Prices for flights from Greenville Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Diego Airport?

  • How old do you have to be to fly from Greenville Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Diego?

Best airlines flying from Greenville to San Diego

Compare and see reviews for airlines that fly from Greenville to San Diego with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $305Free CancellationRating
7.9
4,250 reviews
Search Southwest flights
United AirlinesPriceFrom $312Free CancellationRating
7.4
9,944 reviews
Search United Airlines flights
American AirlinesPriceFrom $312Free CancellationRating
7.1
11,782 reviews
Search American Airlines flights
DeltaPriceFrom $326Free CancellationRating
7.8
8,450 reviews
Search Delta flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
La Mesa
Poway
San Ysidro
Imperial Beach
Borrego Springs
Santee
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Finding the right flight to San Diego from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Greenville.

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Greenville and alert you when they change.

An easier way to manage your San Diego trip

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