Cheap flights from Detroit to San Antonio from $123

If you aren’t able to travel during the month of July, then book flights to San Antonio from Detroit during January instead. Flights to San Antonio in January, while not as cheap as those in July, still average around $428.

The cheapest day to depart on your flight to San Antonio is on a Wednesday when prices can be found for as low as $436. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to San Antonio on Sunday is $545.

According to our data, the cheapest time of day to fly to San Antonio is in the evening. momondo users have found flights departing from Detroit to San Antonio in the evening for as low as $476. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to San Antonio are more costly at noon, with an average ticket price of $479. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Detroit Metropolitan Wayne County to San Antonio for the best Detroit - San Antonio flight prices

You are more likely to see cheaper flights to San Antonio from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from Detroit for as low as $376 on momondo.

There are 4 cabin classes available to choose from on Detroit to San Antonio flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest is the most popular carrier operating from Detroit to San Antonio

Delta, Frontier and Southwest are the top three most popular airlines that fly to San Antonio from Detroit according to our data. Delta is the first choice among our users, with 77% of people opting to fly with this airline when traveling to San Antonio. Keep in mind that there are 4 different airlines that fly to San Antonio on a routine basis, so you have a few additional options to choose from.

Denver (DEN) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $195.

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 5h 26m.

Dallas (DFW) has the shortest average layover time for this route: 1h 06m.

As of October 2026, there are 9 flights per day flying from Detroit to San Antonio. The most common time of day flights depart is 8:00PM, with 48% of flights taking off in the evening.

65 flights are operational weekly from Detroit to San Antonio as of October 2026. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.