Cheap flights from Detroit to San Antonio from $125

If you aren’t able to travel during the month of July, then book flights to San Antonio from Detroit during February instead. Flights to San Antonio in February, while not as cheap as those in July, still average around $424.

The cheapest day to depart on your flight to San Antonio is on a Wednesday when prices can be found for as low as $438. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to San Antonio on Monday is $539.

According to our data, the cheapest time of day to fly to San Antonio is at noon. momondo users have found flights departing from Detroit to San Antonio at noon for as low as $460. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to San Antonio are more costly in the morning, with an average ticket price of $479. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Detroit Metropolitan Wayne County to San Antonio for the best Detroit - San Antonio flight prices

You are more likely to see cheaper flights to San Antonio from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $462 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from Detroit for as low as $376 on momondo.

There are 4 cabin classes available to choose from on Detroit to San Antonio flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Detroit to San Antonio.

As of September 2026, prices for Detroit to San Antonio flights are approximately 21% cheaper when compared to flights at the same time last year.

Southwest and Delta are the most popular carriers operating from Detroit to San Antonio

Delta, Frontier and Southwest are the top three most popular airlines that fly to San Antonio from Detroit according to our data. Delta is the first choice among our users, with 77% of people opting to fly with this airline when traveling to San Antonio. Keep in mind that there are 5 different airlines that fly to San Antonio on a routine basis, so you have a few additional options to choose from.

Denver (DEN) was the most common stop: 75% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $173.

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 5h 26m.

Dallas (DFW) has the shortest average layover time for this route: 1h 06m.

As of September 2026, there are 6 flights per day flying from Detroit to San Antonio. The most common time of day flights depart is 8:00PM, with 54% of flights taking off in the evening.

44 flights are operational weekly from Detroit to San Antonio as of September 2026. The most popular departure day for this route is Fri, with 30% of flights per week taking off on this day.