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Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to San Francisco departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco

Cheap round-trip flights

Multiple Airlines Logo
7:59 pm - 9:29 amDTW-SFO
16h 30m1 stop
Multiple Airlines Logo
12:00 pm - 12:59 amSFO-DTW
33h 59m2 stops
$298Multiple Airlines
Find Deal
vie., oct. 10 - mar., oct. 14
United Airlines Logo
5:45 pm - 7:59 pmDTW-SFO
5h 14mnonstop
United Airlines Logo
5:15 am - 4:51 pmSFO-DTW
8h 36m1 stop
$299United Airlines
Find Deal
vie., oct. 17 - mar., oct. 21
Frontier Logo
6:10 am - 6:19 pmDTW-SFO
15h 09m2 stops
Frontier Logo
6:29 am - 9:59 amSFO-DTW
24h 30m2 stops
$300Frontier
Find Deal
lun., sep. 29 - jue., oct. 2
Frontier Logo
6:00 am - 2:24 pmDTW-SFO
11h 24m1 stop
Frontier Logo
10:25 pm - 2:11 pmSFO-DTW
12h 46m1 stop
$304Frontier
Find Deal
jue., oct. 9 - dom., oct. 12
American Airlines Logo
5:30 am - 9:22 amDTW-SFO
6h 52m1 stop
American Airlines Logo
12:50 am - 10:44 amSFO-DTW
6h 54m1 stop
$309American Airlines
Find Deal
vie., oct. 17 - lun., oct. 20
Southwest Logo
7:00 am - 2:40 pmDTW-SFO
10h 40m2 stops
Southwest Logo
9:50 am - 9:25 pmSFO-DTW
8h 35m1 stop
$312Southwest
Find Deal
lun., dic. 15 - mar., ene. 6
Southwest Logo
8:00 am - 2:40 pmDTW-SFO
9h 40m1 stop
Southwest Logo
6:10 am - 7:50 pmSFO-DTW
10h 40m1 stop
$322Southwest
Find Deal
jue., nov. 20 - vie., nov. 28
American Airlines Logo
3:16 pm - 9:51 pmDTW-SFO
9h 35m1 stop
American Airlines Logo
12:50 am - 10:44 amSFO-DTW
6h 54m1 stop
$323American Airlines
Find Deal
vie., oct. 10 - lun., oct. 13
Delta Logo
8:25 pm - 10:35 pmDTW-SFO
5h 10mnonstop
Delta Logo
10:57 pm - 6:27 amSFO-DTW
4h 30mnonstop
$328Delta
Find Deal
vie., oct. 17 - mar., oct. 21
Delta Logo
8:25 pm - 10:35 pmDTW-SFO
5h 10mnonstop
Delta Logo
10:57 pm - 6:27 amSFO-DTW
4h 30mnonstop
$347Delta
Find Deal
vie., oct. 17 - lun., oct. 20

Delta flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best Delta deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets
Delta
Oct 17
DTW8:25 pmDetroit Metropolitan Wayne County
5h 10m
SFO10:35 pmSan Francisco
Oct 21
SFO10:57 pmSan Francisco
4h 30m
DTW6:27 amDetroit Metropolitan Wayne County
$328
Find similar
Delta
Oct 17
DTW8:25 pmDetroit Metropolitan Wayne County
5h 10m
SFO10:35 pmSan Francisco
Oct 20
SFO10:57 pmSan Francisco
4h 30m
DTW6:27 amDetroit Metropolitan Wayne County
$347
Find similar
Delta
Feb 11
DTW8:20 pmDetroit Metropolitan Wayne County
5h 27m
SFO10:47 pmSan Francisco
Feb 28
SFO10:31 amSan Francisco
16h 57m
1 stop
DTW6:28 amDetroit Metropolitan Wayne County
$350
Find similar

American Airlines flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets
American Airlines
Oct 17
DTW5:30 amDetroit Metropolitan Wayne County
6h 52m
1 stop
SFO9:22 amSan Francisco
Oct 20
SFO12:50 amSan Francisco
6h 54m
1 stop
DTW10:44 amDetroit Metropolitan Wayne County
$309
Find similar
American Airlines
Oct 10
DTW3:16 pmDetroit Metropolitan Wayne County
9h 35m
1 stop
SFO9:51 pmSan Francisco
Oct 13
SFO12:50 amSan Francisco
6h 54m
1 stop
DTW10:44 amDetroit Metropolitan Wayne County
$323
Find similar
American Airlines
Oct 27
DTW6:00 amDetroit Metropolitan Wayne County
9h 31m
1 stop
SFO12:31 pmSan Francisco
Oct 30
SFO12:50 amSan Francisco
6h 53m
1 stop
DTW10:43 amDetroit Metropolitan Wayne County
$337
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 19, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

vie. 10/10

7:59 pm-9:29 am

1 stop16h 30m

San Francisco

mar. 10/14

12:00 pm-12:59 am

2 stops33h 59m

$298

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

vie. 10/17

5:45 pm-7:59 pm

Nonstop5h 14m

San Francisco

mar. 10/21

5:15 am-4:51 pm

1 stop8h 36m

$299

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

lun. 9/29

6:10 am-6:19 pm

2 stops15h 09m

San Francisco

jue. 10/2

6:29 am-9:59 am

2 stops24h 30m

$300

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

jue. 10/9

6:00 am-2:24 pm

1 stop11h 24m

San Francisco

dom. 10/12

10:25 pm-2:11 pm

1 stop12h 46m

$304

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

vie. 10/17

5:30 am-9:22 am

1 stop6h 52m

San Francisco

lun. 10/20

12:50 am-10:44 am

1 stop6h 54m

$309

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

lun. 12/15

7:00 am-2:40 pm

2 stops10h 40m

San Francisco

mar. 1/6

9:50 am-9:25 pm

1 stop8h 35m

$312

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

jue. 11/20

8:00 am-2:40 pm

1 stop9h 40m

San Francisco

vie. 11/28

6:10 am-7:50 pm

1 stop10h 40m

$322

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

vie. 10/10

3:16 pm-9:51 pm

1 stop9h 35m

San Francisco

lun. 10/13

12:50 am-10:44 am

1 stop6h 54m

$323

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

vie. 10/17

8:25 pm-10:35 pm

Nonstop5h 10m

San Francisco

mar. 10/21

10:57 pm-6:27 am

Nonstop4h 30m

$328

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

vie. 10/17

8:25 pm-10:35 pm

Nonstop5h 10m

San Francisco

lun. 10/20

10:57 pm-6:27 am

Nonstop4h 30m

$347

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of July, then flying in June is also cheap. Prices for this month can be found on momondo for an average of $408.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to San Francisco is on a Friday when prices can be found for as low as $585. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $816.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Detroit Metropolitan Wayne County Airport to San Francisco flights are usually those with departure times in the afternoon. Our users have found flights to San Francisco in the afternoon for as low as $607. Flights in the morning are often more expensive with an average ticket price of $669.

What is the cheapest Detroit Metropolitan Wayne County to San Francisco flight route?

Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit Metropolitan Wayne County - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $524 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit Metropolitan Wayne County Airport for as low as $362 on momondo.

What cabin class options are available on Detroit Metropolitan Wayne County to San Francisco flights?

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Detroit Metropolitan Wayne County Airport to San Francisco flight prices changed over time?

As of September 2025, prices for Detroit Metropolitan Wayne County Airport to San Francisco flights are approximately 115% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to San Francisco (DTW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Best Price Found

$273

Fastest flight time

4h 58m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Detroit Metropolitan Wayne County Airport in the past 72 hours is $273. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to San Francisco found on momondo in the last 72 hours is $389.
The fastest flight from Detroit Metropolitan Wayne County Airport to San Francisco takes 4h 58m
Direct flights go from Detroit Metropolitan Wayne County Airport to San Francisco every day.
There is 1 airport near San Francisco: San Francisco (SFO)
Search flight deals

  • How far is Detroit Metropolitan Wayne County to San Francisco by plane?

    The distance between Detroit Metropolitan Wayne County and San Francisco is about 2070.0 mi. A reasonable flight in good conditions will take 5h 10m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to San Francisco?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to San Francisco?

Best airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $101Free CancellationRating
6.3
8,030 reviews
Search Spirit Airlines flights
Sun Country AirPriceFrom $128Free CancellationRating
6.9
330 reviews
Search Sun Country Air flights
FrontierPriceFrom $130Free CancellationRating
5.8
3,171 reviews
Search Frontier flights
JetBluePriceFrom $267Free CancellationRating
7.2
2,911 reviews
Search JetBlue flights
United AirlinesPriceFrom $289Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
7,964 reviews
Search Delta flights
SouthwestPriceFrom $308Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Delta Flights From Detroit Metropolitan Wayne County Airport to San Francisco

    The lowest priced Delta flight from Detroit Metropolitan Wayne County Airport to San Francisco from the last 72 hours was $289. Generally, Delta has 26 flights on this route every week with an average price of $572. Delta is rated 7.9/10 by our users.

  • United Airlines Flights From Detroit Metropolitan Wayne County Airport to San Francisco

    United Airlines (7.4/10 from 8,926 reviews) operates around 12 flights from Detroit Metropolitan Wayne County Airport to San Francisco in any given week. The average United Airlines airfare for this route is around $547, with deals from around $289 rare but found on momondo. Referenced prices are for round-trip Detroit Metropolitan Wayne County Airport to San Francisco flight searches in the last 72 hours.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Calistoga
Bodega Bay
Roseville
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Half Moon Bay
Walnut Creek
Vallejo
Redwood City
Salinas
South San Francisco
Fairfield

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Detroit.

Can I find flights from Detroit to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to San Francisco?

momondo helps you find the best flight between Detroit and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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