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Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to San Francisco departing on 2/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:05 am - 9:32 am
DTW
-
SFO
5h 27mnonstop
United Airlines Logo
1:20 pm - 8:59 pm
SFO
-
DTW
4h 39mnonstop
$289United Airlines
Wed, Feb 18 - Sat, Feb 21
American Airlines Logo
6:35 am - 4:34 pm
DTW
-
SFO
12h 59m1 stop
American Airlines Logo
11:04 am - 10:58 pm
SFO
-
DTW
8h 54m1 stop
$290American Airlines
Sat, Jan 17 - Sun, Jan 18
Frontier Logo
12:19 pm - 8:47 pm
DTW
-
SFO
11h 28m1 stop
Frontier Logo
9:11 pm - 11:24 am
SFO
-
DTW
11h 13m2 stops
$291Frontier
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
7:22 pm - 7:48 am
DTW
-
SFO
15h 26m2 stops
Multiple Airlines Logo
11:20 pm - 10:20 am
SFO
-
DTW
8h 00m1 stop
$292Multiple Airlines
Thu, Jan 15 - Fri, Jan 16
Multiple Airlines Logo
8:00 am - 9:55 am
DTW
-
SFO
28h 55m1 stop
Multiple Airlines Logo
10:14 pm - 5:05 am
SFO
-
DTW
27h 51m2 stops
$293Multiple Airlines
Wed, Jan 14 - Fri, Mar 20
Multiple Airlines Logo
11:54 am - 8:09 pm
DTW
-
SFO
11h 15m1 stop
Multiple Airlines Logo
10:47 pm - 4:35 am
SFO
-
DTW
26h 48m1 stop
$294Multiple Airlines
Tue, Mar 10 - Fri, Mar 27
Multiple Airlines Logo
5:05 am - 1:24 pm
DTW
-
SFO
11h 19m1 stop
Multiple Airlines Logo
9:11 pm - 11:24 am
SFO
-
DTW
11h 13m2 stops
$295Multiple Airlines
Sat, Jan 17 - Sun, Jan 18
Multiple Airlines Logo
8:00 am - 9:55 am
DTW
-
SFO
28h 55m1 stop
Multiple Airlines Logo
9:45 am - 5:05 am
SFO
-
DTW
16h 20m2 stops
$296Multiple Airlines
Wed, Jan 14 - Sat, Mar 21
Multiple Airlines Logo
6:20 am - 11:22 am
DTW
-
SFO
8h 02m1 stop
Multiple Airlines Logo
8:58 am - 11:07 pm
SFO
-
DTW
11h 09m2 stops
$297Multiple Airlines
Fri, Jan 23 - Sat, Feb 14
Multiple Airlines Logo
12:19 pm - 12:28 am
DTW
-
SFO
15h 09m1 stop
Multiple Airlines Logo
8:09 pm - 5:05 am
SFO
-
DTW
29h 56m1 stop
$298Multiple Airlines
Fri, Jan 16 - Fri, Mar 20

United Airlines flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets
United Airlines
Feb 18
DTW7:05 amDetroit Metropolitan Wayne County
5h 27m
SFO9:32 amSan Francisco
Feb 24
SFO1:20 pmSan Francisco
4h 39m
DTW8:59 pmDetroit Metropolitan Wayne County
$289
Find similar
United Airlines
Jan 8
DTW7:10 amDetroit Metropolitan Wayne County
5h 21m
SFO9:31 amSan Francisco
Jan 15
SFO9:20 pmSan Francisco
9h 48m
1 stop
DTW10:08 amDetroit Metropolitan Wayne County
$299
Find similar
United Airlines
Jan 16
DTW7:45 pmDetroit Metropolitan Wayne County
8h 45m
1 stop
SFO1:30 amSan Francisco
Jan 18
SFO5:00 amSan Francisco
7h 08m
1 stop
DTW3:08 pmDetroit Metropolitan Wayne County
$309
Find similar

American Airlines flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets
American Airlines
Jan 17
DTW6:35 amDetroit Metropolitan Wayne County
12h 59m
1 stop
SFO4:34 pmSan Francisco
Jan 18
SFO6:00 amSan Francisco
7h 13m
1 stop
DTW4:13 pmDetroit Metropolitan Wayne County
$290
Find similar
American Airlines
Jan 17
DTW5:35 pmDetroit Metropolitan Wayne County
8h 37m
1 stop
SFO11:12 pmSan Francisco
Jan 24
SFO6:00 amSan Francisco
8h 19m
2 stops
DTW5:19 pmDetroit Metropolitan Wayne County
$314
Find similar
American Airlines
Jan 24
DTW11:20 amDetroit Metropolitan Wayne County
10h 10m
2 stops
SFO6:30 pmSan Francisco
Feb 11
SFO9:10 amSan Francisco
10h 25m
2 stops
DTW10:35 pmDetroit Metropolitan Wayne County
$319
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 2/18

7:05 am-9:32 am

Nonstop5h 27m

San Francisco

Sat 2/21

1:20 pm-8:59 pm

Nonstop4h 39m

$289

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 1/17

6:35 am-4:34 pm

1 stop12h 59m

San Francisco

Sun 1/18

11:04 am-10:58 pm

1 stop8h 54m

$290

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 1/15

12:19 pm-8:47 pm

1 stop11h 28m

San Francisco

Sun 1/18

9:11 pm-11:24 am

2 stops11h 13m

$291

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 1/15

7:22 pm-7:48 am

2 stops15h 26m

San Francisco

Fri 1/16

11:20 pm-10:20 am

1 stop8h 00m

$292

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 1/14

8:00 am-9:55 am

1 stop28h 55m

San Francisco

Fri 3/20

10:14 pm-5:05 am

2 stops27h 51m

$293

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 3/10

11:54 am-8:09 pm

1 stop11h 15m

San Francisco

Fri 3/27

10:47 pm-4:35 am

1 stop26h 48m

$294

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 1/17

5:05 am-1:24 pm

1 stop11h 19m

San Francisco

Sun 1/18

9:11 pm-11:24 am

2 stops11h 13m

$295

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 1/14

8:00 am-9:55 am

1 stop28h 55m

San Francisco

Sat 3/21

9:45 am-5:05 am

2 stops16h 20m

$296

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 1/23

6:20 am-11:22 am

1 stop8h 02m

San Francisco

Sat 2/14

8:58 am-11:07 pm

2 stops11h 09m

$297

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 1/16

12:19 pm-12:28 am

1 stop15h 09m

San Francisco

Fri 3/20

8:09 pm-5:05 am

1 stop29h 56m

$298

Flights are sorted by cheapest round-trip flights first.

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See travel insights to San Francisco from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of July, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $401.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to San Francisco is on a Friday when prices can be found for as low as $523. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $747.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Detroit Metropolitan Wayne County Airport to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $564. Flights in the morning are often more expensive with an average ticket price of $600.

What is the cheapest Detroit Metropolitan Wayne County to San Francisco flight route?

Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit Metropolitan Wayne County - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $472 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit Metropolitan Wayne County Airport for as low as $338 on momondo.

What cabin class options are available on Detroit Metropolitan Wayne County to San Francisco flights?

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Detroit Metropolitan Wayne County Airport to San Francisco flight prices changed over time?

As of December 2025, prices for Detroit Metropolitan Wayne County Airport to San Francisco flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to San Francisco (DTW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Best Price Found

$307

Fastest flight time

5h 16m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Detroit Metropolitan Wayne County Airport in the past 72 hours is $307. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to San Francisco found on momondo in the last 72 hours is $389.
The fastest flight from Detroit Metropolitan Wayne County Airport to San Francisco takes 5h 16m
Direct flights go from Detroit Metropolitan Wayne County Airport to San Francisco every day.
There is 1 airport in San Francisco. From Detroit Metropolitan Wayne County Airport there are direct flights to San Francisco (SFO).
Search flight deals

  • How far is Detroit Metropolitan Wayne County to San Francisco by plane?

    The distance between Detroit Metropolitan Wayne County and San Francisco is about 2070.0 mi. A reasonable flight in good conditions will take 5h 16m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to San Francisco?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to San Francisco?

Best airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Sun Country AirPriceFrom $128Free CancellationRating
6.9
333 reviews
Search Sun Country Air flights
FrontierPriceFrom $140Free CancellationRating
5.8
3,081 reviews
Search Frontier flights
JetBluePriceFrom $279Free CancellationRating
7.2
2,897 reviews
Search JetBlue flights
United AirlinesPriceFrom $289Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
8,005 reviews
Search Delta flights
SouthwestPriceFrom $306Free CancellationRating
7.9
4,250 reviews
Search Southwest flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

  • Delta Flights From Detroit Metropolitan Wayne County Airport to San Francisco

    The lowest priced Delta flight from Detroit Metropolitan Wayne County Airport to San Francisco from the last 72 hours was $289. Generally, Delta has 13 flights on this route every week with an average price of $540. Delta is rated 7.9/10 by our users.

  • United Airlines Flights From Detroit Metropolitan Wayne County Airport to San Francisco

    United Airlines (7.4/10 from 9,091 reviews) operates around 2 flights from Detroit Metropolitan Wayne County Airport to San Francisco in any given week. The average United Airlines airfare for this route is around $416, with deals from around $289 rare but found on momondo. Referenced prices are for round-trip Detroit Metropolitan Wayne County Airport to San Francisco flight searches in the last 72 hours.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Berkeley
Santa Clara
Walnut Creek
Fremont
Daly City
Half Moon Bay
Vallejo
Salinas
Livermore
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Detroit.

Can I find flights from Detroit to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to San Francisco?

momondo helps you find the best flight between Detroit and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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