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Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to San Francisco departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
5:40 pm - 11:04 pm
DTW
-
SFO
8h 24m
1 stop
Frontier Logo
11:59 pm - 4:53 pm
SFO
-
DTW
13h 54m
1 stop
$290Frontier
Sel, Ags 18 - Jum, Ags 28
Frontier Logo
9:54 pm - 8:00 pm
DTW
-
SFO
25h 06m
2 stops
Frontier Logo
11:59 pm - 4:53 pm
SFO
-
DTW
13h 54m
1 stop
$291Frontier
Sel, Mei 26 - Sen, Jun 1
Frontier Logo
9:02 am - 7:14 pm
DTW
-
SFO
13h 12m
1 stop
Frontier Logo
6:00 am - 10:12 am
SFO
-
DTW
25h 12m
2 stops
$292Frontier
Sen, Mar 23 - Rab, Apr 8
Frontier Logo
9:02 am - 7:19 pm
DTW
-
SFO
13h 17m
1 stop
Frontier Logo
11:16 pm - 11:16 am
SFO
-
DTW
9h 00m
1 stop
$293Frontier
Sab, Apr 11 - Min, Mei 3
Frontier Logo
7:45 am - 12:52 pm
DTW
-
SFO
8h 07m
1 stop
Frontier Logo
7:40 pm - 11:16 am
SFO
-
DTW
12h 36m
2 stops
$294Frontier
Kam, Apr 2 - Rab, Apr 22
Frontier Logo
9:02 am - 7:14 pm
DTW
-
SFO
13h 12m
1 stop
Frontier Logo
9:04 pm - 10:59 am
SFO
-
DTW
10h 55m
1 stop
$295Frontier
Sel, Mar 24 - Jum, Mar 27
Frontier Logo
9:02 am - 7:14 pm
DTW
-
SFO
13h 12m
1 stop
Frontier Logo
9:04 pm - 10:59 am
SFO
-
DTW
10h 55m
1 stop
$296Frontier
Rab, Mar 25 - Jum, Mar 27
Frontier Logo
9:02 am - 7:14 pm
DTW
-
SFO
13h 12m
1 stop
Frontier Logo
7:40 pm - 11:16 am
SFO
-
DTW
12h 36m
2 stops
$297Frontier
Rab, Mar 25 - Sab, Apr 18
Frontier Logo
4:22 pm - 12:23 am
DTW
-
SFO
11h 01m
1 stop
Frontier Logo
10:57 pm - 8:02 am
SFO
-
DTW
54h 05m
2 stops
$298Frontier
Rab, Apr 1 - Min, Apr 5
Frontier Logo
11:54 am - 12:27 am
DTW
-
SFO
15h 33m
1 stop
Frontier Logo
9:20 pm - 12:44 am
SFO
-
DTW
24h 24m
2 stops
$299Frontier
Jum, Apr 17 - Min, Apr 19

United Airlines flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets
United Airlines
Apr 25
DTW7:10 amDetroit Metropolitan Wayne County
5h 20m
SFO9:30 amSan Francisco
May 23
SFO9:30 pmSan Francisco
4h 50m
DTW5:20 amDetroit Metropolitan Wayne County
$309
United Airlines
Apr 8
DTW7:10 amDetroit Metropolitan Wayne County
5h 20m
SFO9:30 amSan Francisco
Apr 12
SFO11:52 pmSan Francisco
6h 51m
1 stop
DTW9:43 amDetroit Metropolitan Wayne County
$319
United Airlines
Jul 22
DTW5:29 pmDetroit Metropolitan Wayne County
5h 11m
SFO7:40 pmSan Francisco
Jul 25
SFO9:30 pmSan Francisco
4h 50m
DTW5:20 amDetroit Metropolitan Wayne County
$336

Frontier flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best Frontier deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets
Frontier
Aug 18
DTW5:40 pmDetroit Metropolitan Wayne County
8h 24m
1 stop
SFO11:04 pmSan Francisco
Aug 28
SFO11:59 pmSan Francisco
13h 54m
1 stop
DTW4:53 pmDetroit Metropolitan Wayne County
$290
Frontier
May 26
DTW9:54 pmDetroit Metropolitan Wayne County
25h 06m
2 stops
SFO8:00 pmSan Francisco
Jun 1
SFO11:59 pmSan Francisco
13h 54m
1 stop
DTW4:53 pmDetroit Metropolitan Wayne County
$291
Frontier
Mar 23
DTW9:02 amDetroit Metropolitan Wayne County
13h 12m
1 stop
SFO7:14 pmSan Francisco
Apr 8
SFO6:00 amSan Francisco
25h 12m
2 stops
DTW10:12 amDetroit Metropolitan Wayne County
$292

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Maret 12, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sel 8/18

5:40 pm-11:04 pm

1 stop8h 24m

San Francisco

Jum 8/28

11:59 pm-4:53 pm

1 stop13h 54m

$290

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sel 5/26

9:54 pm-8:00 pm

2 stops25h 06m

San Francisco

Sen 6/1

11:59 pm-4:53 pm

1 stop13h 54m

$291

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sen 3/23

9:02 am-7:14 pm

1 stop13h 12m

San Francisco

Rab 4/8

6:00 am-10:12 am

2 stops25h 12m

$292

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sab 4/11

9:02 am-7:19 pm

1 stop13h 17m

San Francisco

Min 5/3

11:16 pm-11:16 am

1 stop9h 00m

$293
Quickest round-trip

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Kam 4/2

7:45 am-12:52 pm

1 stop8h 07m

San Francisco

Rab 4/22

7:40 pm-11:16 am

2 stops12h 36m

$294

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sel 3/24

9:02 am-7:14 pm

1 stop13h 12m

San Francisco

Jum 3/27

9:04 pm-10:59 am

1 stop10h 55m

$295

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Rab 3/25

9:02 am-7:14 pm

1 stop13h 12m

San Francisco

Jum 3/27

9:04 pm-10:59 am

1 stop10h 55m

$296

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Rab 3/25

9:02 am-7:14 pm

1 stop13h 12m

San Francisco

Sab 4/18

7:40 pm-11:16 am

2 stops12h 36m

$297

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Rab 4/1

4:22 pm-12:23 am

1 stop11h 01m

San Francisco

Min 4/5

10:57 pm-8:02 am

2 stops54h 05m

$298

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Jum 4/17

11:54 am-12:27 am

1 stop15h 33m

San Francisco

Min 4/19

9:20 pm-12:44 am

2 stops24h 24m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of July, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $389.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to San Francisco is on a Thursday when prices can be found for as low as $483. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $658.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Detroit Metropolitan Wayne County Airport to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $501. Flights in the afternoon are often more expensive with an average ticket price of $559.

What is the cheapest Detroit Metropolitan Wayne County to San Francisco flight route?

Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit Metropolitan Wayne County - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit Metropolitan Wayne County Airport for as low as $350 on momondo.

What cabin class options are available on Detroit Metropolitan Wayne County to San Francisco flights?

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Detroit Metropolitan Wayne County Airport to San Francisco flight prices changed over time?

As of March 2026, prices for Detroit Metropolitan Wayne County Airport to San Francisco flights are approximately 19% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to San Francisco (DTW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Best Price Found

$305

Fastest flight time

5h 05m

Direct flights

Every day

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Detroit Metropolitan Wayne County Airport in the past 72 hours is $305. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to San Francisco found on momondo in the last 72 hours is $418.
The fastest flight from Detroit Metropolitan Wayne County Airport to San Francisco takes 5h 05m
Direct flights go from Detroit Metropolitan Wayne County Airport to San Francisco every day.
There is 1 airport in San Francisco. From Detroit Metropolitan Wayne County Airport there are direct flights to San Francisco (SFO).
Search flight deals

  • How far is Detroit Metropolitan Wayne County to San Francisco by plane?

    The distance between Detroit Metropolitan Wayne County and San Francisco is about 2070.0 mi. A reasonable flight in good conditions will take 5h 05m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to San Francisco?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to San Francisco?

Best airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Sun Country AirPriceFrom $126Free CancellationRating
6.8
342 reviews
Search Sun Country Air flights
FrontierPriceFrom $150Free CancellationRating
5.7
3,031 reviews
Search Frontier flights
JetBluePriceFrom $259Free CancellationRating
7.2
2,904 reviews
Search JetBlue flights
SouthwestPriceFrom $288Free CancellationRating
8.0
4,319 reviews
Search Southwest flights
United AirlinesPriceFrom $289Free CancellationRating
7.4
9,421 reviews
Search United Airlines flights
DeltaPriceFrom $289Free CancellationRating
7.9
8,285 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,442 reviews
Search American Airlines flights

  • Delta Flights From Detroit Metropolitan Wayne County Airport to San Francisco

    The lowest priced Delta flight from Detroit Metropolitan Wayne County Airport to San Francisco from the last 72 hours was $289. Generally, Delta has 22 flights on this route every week with an average price of $502. Delta is rated 7.9/10 by our users.

  • United Airlines Flights From Detroit Metropolitan Wayne County Airport to San Francisco

    United Airlines (7.4/10 from 9,421 reviews) operates around 7 flights from Detroit Metropolitan Wayne County Airport to San Francisco in any given week. The average United Airlines airfare for this route is around $396, with deals from around $289 rare but found on momondo. Referenced prices are for round-trip Detroit Metropolitan Wayne County Airport to San Francisco flight searches in the last 72 hours.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Walnut Creek
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Half Moon Bay
Daly City
South San Francisco
Pacific Grove
Milpitas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Detroit.

Can I find flights from Detroit to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to San Francisco?

momondo helps you find the best flight between Detroit and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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