What is the cheapest airline that flies from Detroit Metropolitan Wayne County to San Francisco?

Southwest, Delta, and Alaska Airlines are the most popular carriers operating from Detroit Metropolitan Wayne County to San Francisco

What airlines fly to San Francisco?

Delta, United Airlines and Southwest are the top three most popular airlines that fly to San Francisco from Detroit Metropolitan Wayne County Airport according to our data. Delta is the first choice among our users, with 48% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 7 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Detroit Metropolitan Wayne County Airport to San Francisco?

Flights connecting via St. Louis (STL) have the shortest average one-way travel time: 6h 40m.

Which airport is the most popular layover for flights between Detroit Metropolitan Wayne County Airport and San Francisco?

Denver (DEN) was the most common stop: 38% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Detroit Metropolitan Wayne County Airport to San Francisco?

Flights via Denver (DEN) offer the lowest average round-trip price of $227.

Which layover airport has the shortest connection time from Detroit Metropolitan Wayne County Airport to San Francisco?

Chicago (ORD) has the shortest average layover time for this route: 1h 03m.

What documentation or ID do you need to fly to San Francisco Airport?

The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$190 Cheap Flights from Detroit Metropolitan Wayne County Airport to San Francisco in 2026

Q: How many flights depart from Detroit Metropolitan Wayne County Airport to San Francisco on average per week?

As of June 2026, there are 66 flights per week flying from Detroit Metropolitan Wayne County Airport to San Francisco. The most common day of the week flights depart is Mon, with 23% of flights taking off on this day.

Q: How many flights depart from Detroit Metropolitan Wayne County Airport to San Francisco on average per day?

The number of flights available between Detroit Metropolitan Wayne County Airport and San Francisco is 9 per day as of June 2026. The most frequent departure time is 3:00PM, with 58% of daily flights leaving in the afternoon.

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco

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Enter your travel dates to find the best prices.

6:00 am - 1:38 pm

DTW

SFO

10h 38m

1 stop

10:10 pm - 11:21 am

SFO

DTW

10h 11m

1 stop

$343JetBlue

Thu, Nov 5 - Sun, Nov 15

7:30 am - 1:55 pm

DTW

SFO

9h 25m

1 stop

12:38 pm - 11:59 pm

SFO

DTW

8h 21m

1 stop

$344Multiple Airlines

Sat, Jun 27 - Sat, Jul 4

8:30 am - 9:38 pm

DTW

SFO

16h 08m

2 stops

11:05 pm - 1:44 pm

SFO

DTW

11h 39m

1 stop

$345Frontier

Tue, Jul 28 - Fri, Aug 7

6:47 pm - 11:43 am

DTW

SFO

19h 56m

2 stops

7:08 pm - 7:21 am

SFO

DTW

9h 13m

1 stop

$346Frontier

Mon, Jul 20 - Thu, Jul 23

2:56 pm - 10:30 am

DTW

SFO

22h 34m

2 stops

7:04 pm - 7:21 am

SFO

DTW

9h 17m

1 stop

$347Frontier

Tue, Jul 7 - Tue, Jul 14

8:30 am - 3:25 pm

DTW

SFO

9h 55m

1 stop

6:00 am - 11:59 pm

SFO

DTW

14h 59m

1 stop

$348Frontier

Wed, Jul 22 - Tue, Jul 28

6:34 am - 8:40 am

DTW

SFO

5h 06mnonstop

9:30 pm - 5:20 am

SFO

DTW

4h 50mnonstop

$349United Airlines

Thu, Jul 2 - Thu, Jul 9

8:30 am - 3:25 pm

DTW

SFO

9h 55m

1 stop

7:08 pm - 7:21 am

SFO

DTW

9h 13m

1 stop

$350Frontier

Wed, Jul 29 - Wed, Aug 5

8:30 am - 3:25 pm

DTW

SFO

9h 55m

1 stop

6:00 am - 5:48 pm

SFO

DTW

8h 48m

1 stop

$351Multiple Airlines

Wed, Jul 29 - Tue, Aug 11

7:44 pm - 8:45 pm

DTW

SFO

28h 01m

2 stops

9:39 pm - 12:34 pm

SFO

DTW

11h 55m

1 stop

$352Frontier

Fri, Jul 10 - Sun, Jul 12

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JetBlue flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best JetBlue deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets

JetBlue

Nov 5

DTW6:00 amDetroit Metropolitan Wayne County

10h 38m

1 stop

SFO1:38 pmSan Francisco

Nov 15

SFO10:10 pmSan Francisco

10h 11m

1 stop

DTW11:21 amDetroit Metropolitan Wayne County

$343

JetBlue

Nov 6

DTW4:45 pmDetroit Metropolitan Wayne County

10h 13m

1 stop

SFO11:58 pmSan Francisco

Nov 13

SFO12:15 pmSan Francisco

8h 41m

1 stop

DTW11:56 pmDetroit Metropolitan Wayne County

$380

JetBlue

Jun 29

DTW3:08 pmDetroit Metropolitan Wayne County

12h 23m

1 stop

SFO12:31 amSan Francisco

Jul 9

SFO10:25 amSan Francisco

9h 20m

1 stop

DTW10:45 pmDetroit Metropolitan Wayne County

$382

Delta flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best Delta deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets

Delta

Jul 2

DTW6:55 pmDetroit Metropolitan Wayne County

5h 04m

SFO8:59 pmSan Francisco

Jul 9

SFO10:55 pmSan Francisco

4h 32m

DTW6:27 amDetroit Metropolitan Wayne County

$349

Delta

Jun 29

DTW6:55 pmDetroit Metropolitan Wayne County

5h 04m

SFO8:59 pmSan Francisco

Jul 3

SFO10:55 pmSan Francisco

4h 35m

DTW6:30 amDetroit Metropolitan Wayne County

$359

Delta

Jul 16

DTW8:37 pmDetroit Metropolitan Wayne County

4h 58m

SFO10:35 pmSan Francisco

Jul 19

SFO11:56 pmSan Francisco

4h 31m

DTW7:27 amDetroit Metropolitan Wayne County

$379

momondo Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

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Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 11/5

6:00 am-1:38 pm

1 stop10h 38m

San Francisco

Sun 11/15

10:10 pm-11:21 am

1 stop10h 11m

$343

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 6/27

7:30 am-1:55 pm

1 stop9h 25m

San Francisco

Sat 7/4

12:38 pm-11:59 pm

1 stop8h 21m

$344

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 7/28

8:30 am-9:38 pm

2 stops16h 08m

San Francisco

Fri 8/7

11:05 pm-1:44 pm

1 stop11h 39m

$345

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Mon 7/20

6:47 pm-11:43 am

2 stops19h 56m

San Francisco

Thu 7/23

7:08 pm-7:21 am

1 stop9h 13m

$346

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 7/7

2:56 pm-10:30 am

2 stops22h 34m

San Francisco

Tue 7/14

7:04 pm-7:21 am

1 stop9h 17m

$347

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 7/22

8:30 am-3:25 pm

1 stop9h 55m

San Francisco

Tue 7/28

6:00 am-11:59 pm

1 stop14h 59m

$348

Quickest round-trip

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 7/2

6:34 am-8:40 am

Nonstop5h 06m

San Francisco

Thu 7/9

9:30 pm-5:20 am

Nonstop4h 50m

$349

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 7/29

8:30 am-3:25 pm

1 stop9h 55m

San Francisco

Wed 8/5

7:08 pm-7:21 am

1 stop9h 13m

$350

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 7/29

8:30 am-3:25 pm

1 stop9h 55m

San Francisco

Tue 8/11

6:00 am-5:48 pm

1 stop8h 48m

$351

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 7/10

7:44 pm-8:45 pm

2 stops28h 01m

San Francisco

Sun 7/12

9:39 pm-12:34 pm

1 stop11h 55m

$352

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of January, then flying in July is also cheap. Prices for this month can be found on momondo for an average of $398.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to San Francisco is on a Thursday when prices can be found for as low as $497. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $683.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Detroit Metropolitan Wayne County Airport to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $504. Flights in the afternoon are often more expensive with an average ticket price of $579.

What is the cheapest Detroit Metropolitan Wayne County to San Francisco flight route?

Fly from Detroit Metropolitan Wayne County to San Francisco for the best Detroit Metropolitan Wayne County - San Francisco flight prices

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

You are more likely to see cheaper flights to San Francisco from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $452 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Detroit Metropolitan Wayne County Airport for as low as $361 on momondo.

What cabin class options are available on Detroit Metropolitan Wayne County Airport to San Francisco flights?

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County Airport to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Detroit Metropolitan Wayne County Airport to San Francisco flight prices changed over time?

As of June 2026, prices for Detroit Metropolitan Wayne County Airport to San Francisco flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to San Francisco (DTW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Best Price Found	$339
Fastest flight time	4h 51m
Direct flights	Every day
Airports in San Francisco	1 airport

The best one-way flight to San Francisco from Detroit Metropolitan Wayne County Airport in the past 72 hours is $339. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to San Francisco found on momondo in the last 72 hours is $455.

The fastest flight from Detroit Metropolitan Wayne County Airport to San Francisco takes 4h 51m

Direct flights go from Detroit Metropolitan Wayne County Airport to San Francisco every day.

There is 1 airport in San Francisco. From Detroit Metropolitan Wayne County Airport there are direct flights to San Francisco (SFO).

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Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to San Francisco

How far is Detroit Metropolitan Wayne County to San Francisco by plane?
The distance between Detroit Metropolitan Wayne County and San Francisco is about 2069.7 mi. A reasonable flight in good conditions will take 4h 51m.
When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?
Prices for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport?
The number of operators available for flights from Detroit Metropolitan Wayne County Airport to San Francisco Airport is 7 as of June 2026.
How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to San Francisco Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Detroit Metropolitan Wayne County Airport to San Francisco?
momondo data reveals that the most frequently booked plane model on the route from Detroit Metropolitan Wayne County Airport to San Francisco is Boeing 737-900, representing 35.62% of all bookings. The subsequent popular models are Airbus A319 at 24.09%, Boeing 737 MAX 9 at 12.85%, and Airbus A321neo at 7.32%.
What is the most popular airline from Detroit Metropolitan Wayne County Airport to San Francisco?
Based on momondo bookings for flights between Detroit Metropolitan Wayne County Airport and San Francisco, the leading airline is Delta, making up 45% of the total bookings. Other popular airlines include United Airlines with 37%, Frontier with 8%, and Southwest with 4%.

Best airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
Sun Country Air	PriceFrom $107	Free Cancellation	Rating 6.8 330 reviews	Search Sun Country Air flights
Frontier	PriceFrom $155	Free Cancellation	Rating 5.6 2,903 reviews	Search Frontier flights
JetBlue	PriceFrom $259	Free Cancellation	Rating 7.1 2,980 reviews	Search JetBlue flights
United Airlines	PriceFrom $289	Free Cancellation	Rating 7.4 9,794 reviews	Search United Airlines flights
Southwest	PriceFrom $306	Free Cancellation	Rating 7.9 4,243 reviews	Search Southwest flights
American Airlines	PriceFrom $308	Free Cancellation	Rating 7.1 11,643 reviews	Search American Airlines flights
Delta	PriceFrom $342	Free Cancellation	Rating 7.9 8,394 reviews	Search Delta flights

Delta Flights From Detroit Metropolitan Wayne County Airport to San Francisco
The lowest priced Delta flight from Detroit Metropolitan Wayne County Airport to San Francisco from the last 72 hours was $342. Generally, Delta has 28 flights on this route every week with an average price of $554. Delta is rated 7.9/10 by our users.
United Airlines Flights From Detroit Metropolitan Wayne County Airport to San Francisco
United Airlines (7.4/10 from 9,794 reviews) operates around 5 flights from Detroit Metropolitan Wayne County Airport to San Francisco in any given week. The average United Airlines airfare for this route is around $413, with deals from around $289 rare but found on momondo. Referenced prices are for round-trip Detroit Metropolitan Wayne County Airport to San Francisco flight searches in the last 72 hours.

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Modesto

Sonoma

Hayward

Roseville

Bodega Bay

Walnut Creek

Santa Clara

Berkeley

Fremont

Vallejo

Sunnyvale

Big Sur

South San Francisco

Pacific Grove

Daly City

Burlingame

Calistoga

Salinas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Detroit.

Can I find flights from Detroit to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to San Francisco?

momondo helps you find the best flight between Detroit and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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JetBlue flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best JetBlue deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets

Delta flights from Detroit Metropolitan Wayne County Airport to San Francisco

Our best Delta deals on Detroit Metropolitan Wayne County Airport to San Francisco flight tickets

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Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

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How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to San Francisco

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and San Francisco?

What is the cheapest month to fly to San Francisco?

What is the cheapest day to depart on your flight to San Francisco?

What is the cheapest time of day to depart on your flight to San Francisco?

What is the cheapest Detroit Metropolitan Wayne County to San Francisco flight route?

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

What cabin class options are available on Detroit Metropolitan Wayne County Airport to San Francisco flights?

How have Detroit Metropolitan Wayne County Airport to San Francisco flight prices changed over time?

What is the cheapest airline that flies from Detroit Metropolitan Wayne County to San Francisco?

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Detroit Metropolitan Wayne County Airport and San Francisco?

Which layover airport offers the lowest fares from Detroit Metropolitan Wayne County Airport to San Francisco?

Which layover airport has the shortest travel time from Detroit Metropolitan Wayne County Airport to San Francisco?

Which layover airport has the shortest connection time from Detroit Metropolitan Wayne County Airport to San Francisco?

How many flights depart from Detroit Metropolitan Wayne County Airport to San Francisco on average per day?

How many flights depart from Detroit Metropolitan Wayne County Airport to San Francisco on average per week?

When to book flights from Detroit Metropolitan Wayne County Airport to San Francisco

Cheap Detroit Metropolitan Wayne County Airport to San Francisco (DTW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Best Price Found

Fastest flight time

Direct flights

Airports in San Francisco

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to San Francisco

Best airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco with momondo

Delta Flights From Detroit Metropolitan Wayne County Airport to San Francisco

United Airlines Flights From Detroit Metropolitan Wayne County Airport to San Francisco

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