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Cheap flights from Des Moines to San Francisco from $199

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Francisco departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:37 am - 12:30 pm
DSM
-
STS
8h 53m
1 stop
American Airlines Logo
1:00 pm - 11:48 pm
STS
-
DSM
8h 48m
1 stop
$387American Airlines
Wed, Jul 15 - Tue, Jul 21
American Airlines Logo
5:12 am - 12:03 pm
DSM
-
STS
8h 51m
1 stop
American Airlines Logo
1:00 pm - 11:58 pm
STS
-
DSM
8h 58m
2 stops
$392American Airlines
Wed, Jul 15 - Tue, Jul 21
Southwest Logo
12:05 pm - 9:30 pm
DSM
-
STS
11h 25m
2 stops
Southwest Logo
7:40 am - 8:55 pm
STS
-
DSM
11h 15m
2 stops
$397Southwest
Wed, Oct 7 - Wed, Oct 14
Southwest Logo
12:10 pm - 10:50 pm
DSM
-
STS
12h 40m
2 stops
Southwest Logo
6:00 am - 9:45 pm
STS
-
DSM
13h 45m
2 stops
$403Southwest
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
2:25 pm - 10:35 pm
DSM
-
STS
10h 10m
2 stops
Southwest Logo
6:00 am - 5:45 pm
STS
-
DSM
9h 45m
2 stops
$428Southwest
Thu, Sep 17 - Tue, Sep 22
American Airlines Logo
5:12 am - 12:03 pm
DSM
-
STS
8h 51m
1 stop
American Airlines Logo
1:00 pm - 11:48 pm
STS
-
DSM
8h 48m
1 stop
$443American Airlines
Mon, Jul 20 - Tue, Aug 4
American Airlines Logo
5:12 am - 12:03 pm
DSM
-
STS
8h 51m
1 stop
American Airlines Logo
1:00 pm - 11:58 pm
STS
-
DSM
8h 58m
2 stops
$448American Airlines
Mon, Jul 20 - Tue, Aug 4
Southwest Logo
6:10 am - 4:35 pm
DSM
-
STS
12h 25m
2 stops
Southwest Logo
6:00 am - 5:45 pm
STS
-
DSM
9h 45m
2 stops
$477Southwest
Mon, Jul 20 - Tue, Aug 4
American Airlines Logo
5:12 am - 3:42 pm
DSM
-
STS
12h 30m
2 stops
American Airlines Logo
1:00 pm - 11:58 pm
STS
-
DSM
8h 58m
2 stops
$493American Airlines
Wed, Jul 15 - Tue, Jul 21
American Airlines Logo
5:12 am - 12:03 pm
DSM
-
STS
8h 51m
1 stop
American Airlines Logo
12:58 pm - 8:46 pm
STS
-
DSM
5h 48m
1 stop
$505American Airlines
Tue, Aug 4 - Sat, Aug 8

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Southwest flights from Des Moines to Santa Rosa

Our best Southwest deals on Des Moines to Santa Rosa flight tickets
Southwest
Oct 7
DSM12:05 pmDes Moines
11h 25m
2 stops
STS9:30 pmSanta Rosa Sonoma County
Oct 14
STS7:40 amSanta Rosa Sonoma County
11h 15m
2 stops
DSM8:55 pmDes Moines
$397
Southwest
Jul 21
DSM12:10 pmDes Moines
12h 40m
2 stops
STS10:50 pmSanta Rosa Sonoma County
Jul 28
STS6:00 amSanta Rosa Sonoma County
13h 45m
2 stops
DSM9:45 pmDes Moines
$403
Southwest
Sep 17
DSM2:25 pmDes Moines
10h 10m
2 stops
STS10:35 pmSanta Rosa Sonoma County
Sep 22
STS6:00 amSanta Rosa Sonoma County
9h 45m
2 stops
DSM5:45 pmDes Moines
$428

American Airlines flights from Des Moines to Santa Rosa

Our best American Airlines deals on Des Moines to Santa Rosa flight tickets
American Airlines
Jul 15
DSM5:37 amDes Moines
8h 53m
1 stop
STS12:30 pmSanta Rosa Sonoma County
Jul 21
STS1:00 pmSanta Rosa Sonoma County
8h 48m
1 stop
DSM11:48 pmDes Moines
$387
American Airlines
Jul 15
DSM5:12 amDes Moines
8h 51m
1 stop
STS12:03 pmSanta Rosa Sonoma County
Jul 21
STS1:00 pmSanta Rosa Sonoma County
8h 58m
2 stops
DSM11:58 pmDes Moines
$392
American Airlines
Jul 20
DSM5:12 amDes Moines
8h 51m
1 stop
STS12:03 pmSanta Rosa Sonoma County
Aug 4
STS1:00 pmSanta Rosa Sonoma County
8h 48m
1 stop
DSM11:48 pmDes Moines
$443

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Rosa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Des Moines to Santa Rosa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 7/15

5:37 am-12:30 pm

1 stop8h 53m

Santa Rosa Sonoma County

Tue 7/21

1:00 pm-11:48 pm

1 stop8h 48m

$387

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 7/15

5:12 am-12:03 pm

1 stop8h 51m

Santa Rosa Sonoma County

Tue 7/21

1:00 pm-11:58 pm

2 stops8h 58m

$392

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 10/7

12:05 pm-9:30 pm

2 stops11h 25m

Santa Rosa Sonoma County

Wed 10/14

7:40 am-8:55 pm

2 stops11h 15m

$397

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 7/21

12:10 pm-10:50 pm

2 stops12h 40m

Santa Rosa Sonoma County

Tue 7/28

6:00 am-9:45 pm

2 stops13h 45m

$403

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Thu 9/17

2:25 pm-10:35 pm

2 stops10h 10m

Santa Rosa Sonoma County

Tue 9/22

6:00 am-5:45 pm

2 stops9h 45m

$428

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Mon 7/20

5:12 am-12:03 pm

1 stop8h 51m

Santa Rosa Sonoma County

Tue 8/4

1:00 pm-11:48 pm

1 stop8h 48m

$443

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Mon 7/20

5:12 am-12:03 pm

1 stop8h 51m

Santa Rosa Sonoma County

Tue 8/4

1:00 pm-11:58 pm

2 stops8h 58m

$448

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Mon 7/20

6:10 am-4:35 pm

2 stops12h 25m

Santa Rosa Sonoma County

Tue 8/4

6:00 am-5:45 pm

2 stops9h 45m

$477

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 7/15

5:12 am-3:42 pm

2 stops12h 30m

Santa Rosa Sonoma County

Tue 7/21

1:00 pm-11:58 pm

2 stops8h 58m

$493
Quickest round-trip

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 8/4

5:12 am-12:03 pm

1 stop8h 51m

Santa Rosa Sonoma County

Sat 8/8

12:58 pm-8:46 pm

1 stop5h 48m

$505

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Santa Rosa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to Santa Rosa flights?

You could potentially save up to 7% on your flight if you consider stops on a Des Moines to Santa Rosa flight.

When to book flights from Des Moines to Santa Rosa

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Rosa according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santa Rosa (DSM to STS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Rosa

Fastest flight time

8h 40m

Direct flights

None
The fastest flight from Des Moines to Santa Rosa takes 8h 40m
There are no direct flights from Des Moines to Santa Rosa. There are no popular flight routes from Des Moines to Santa Rosa.
Search flight deals

Frequently asked questions about flying from Des Moines to Santa Rosa

  • How far is Des Moines to Santa Rosa Sonoma County by plane?

    There are 1545.9 mi between Des Moines and Santa Rosa Sonoma County. Typically, this will take 8h 40m by plane in normal conditions.

  • When did momondo last update prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

    Prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

  • How old do you have to be to fly from Des Moines Airport to Santa Rosa Sonoma County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Rosa Sonoma County Airport.

  • What documentation or ID do you need to fly to Santa Rosa Sonoma County Airport?

    The required travel and health documents for your Santa Rosa Sonoma County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Rosa Sonoma County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Des Moines to Santa Rosa?

Best airlines flying from Des Moines to Santa Rosa

Compare and see reviews for airlines that fly from Des Moines to Santa Rosa with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $544Free CancellationRating
7.1
11,746 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Fort Bragg
Mendocino
Ukiah
Little River
Point Arena

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Rosa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Santa Rosa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Santa Rosa with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Rosa from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Santa Rosa?

Once all potential Des Moines to Santa Rosa flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Santa Rosa right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Rosa from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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