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Cheap flights from Des Moines to San Francisco from $574

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Francisco departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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American Airlines Logo
5:21 am - 12:27 pmDSM-STS
9h 06m1 stop
American Airlines Logo
12:57 pm - 10:59 pmSTS-DSM
8h 02m2 stops
$574American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
5:15 am - 12:28 pmDSM-STS
9h 13m1 stop
American Airlines Logo
4:12 pm - 12:04 amSTS-DSM
5h 52m1 stop
$609American Airlines
Find Deal
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
5:21 am - 12:27 pmDSM-STS
9h 06m1 stop
American Airlines Logo
12:57 pm - 10:59 pmSTS-DSM
8h 02m2 stops
$614American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
5:00 am - 12:28 pmDSM-STS
9h 28m1 stop
American Airlines Logo
4:12 pm - 12:04 amSTS-DSM
5h 52m1 stop
$664American Airlines
Find Deal
Thu, Mar 5 - Wed, Mar 11
American Airlines Logo
5:00 am - 3:57 pmDSM-STS
12h 57m2 stops
American Airlines Logo
4:12 pm - 12:04 amSTS-DSM
5h 52m1 stop
$669American Airlines
Find Deal
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
5:00 am - 12:27 pmDSM-STS
9h 27m2 stops
American Airlines Logo
12:57 pm - 10:59 pmSTS-DSM
8h 02m2 stops
$674American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
5:15 am - 12:28 pmDSM-STS
9h 13m1 stop
American Airlines Logo
4:12 pm - 12:04 amSTS-DSM
5h 52m1 stop
$677American Airlines
Find Deal
Wed, Mar 4 - Fri, Mar 13
American Airlines Logo
5:00 am - 12:27 pmDSM-STS
9h 27m2 stops
American Airlines Logo
12:57 pm - 10:59 pmSTS-DSM
8h 02m2 stops
$708American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
Alaska Airlines Logo
2:24 pm - 12:08 pmDSM-STS
23h 44m2 stops
Alaska Airlines Logo
7:00 pm - 6:02 pmSTS-DSM
21h 02m2 stops
$719Alaska Airlines
Find Deal
Thu, Mar 5 - Thu, Mar 12
Alaska Airlines Logo
5:21 am - 10:53 pmDSM-STS
19h 32m2 stops
Alaska Airlines Logo
7:00 pm - 6:02 pmSTS-DSM
21h 02m2 stops
$849Alaska Airlines
Find Deal
Sun, Mar 8 - Sun, Mar 15

American Airlines flights from Des Moines to Santa Rosa

Our best American Airlines deals on Des Moines to Santa Rosa flight tickets
American Airlines
Dec 10
DSM5:21 amDes Moines
9h 06m
1 stop
STS12:27 pmSanta Rosa Sonoma County
Dec 13
STS12:57 pmSanta Rosa Sonoma County
8h 02m
2 stops
DSM10:59 pmDes Moines
$574
Find similar
American Airlines
Mar 4
DSM5:15 amDes Moines
9h 13m
1 stop
STS12:28 pmSanta Rosa Sonoma County
Mar 11
STS4:12 pmSanta Rosa Sonoma County
5h 52m
1 stop
DSM12:04 amDes Moines
$609
Find similar
American Airlines
Dec 10
DSM5:21 amDes Moines
9h 06m
1 stop
STS12:27 pmSanta Rosa Sonoma County
Dec 13
STS12:57 pmSanta Rosa Sonoma County
8h 02m
2 stops
DSM10:59 pmDes Moines
$614
Find similar

Alaska Airlines flights from Des Moines to Santa Rosa

Our best Alaska Airlines deals on Des Moines to Santa Rosa flight tickets
Alaska Airlines
Mar 5
DSM2:24 pmDes Moines
23h 44m
2 stops
STS12:08 pmSanta Rosa Sonoma County
Mar 12
STS7:00 pmSanta Rosa Sonoma County
21h 02m
2 stops
DSM6:02 pmDes Moines
$719
Find similar
Alaska Airlines
Mar 8
DSM5:21 amDes Moines
19h 32m
2 stops
STS10:53 pmSanta Rosa Sonoma County
Mar 15
STS7:00 pmSanta Rosa Sonoma County
21h 02m
2 stops
DSM6:02 pmDes Moines
$849
Find similar
Alaska Airlines
Mar 8
DSM5:21 amDes Moines
19h 32m
2 stops
STS10:53 pmSanta Rosa Sonoma County
Mar 15
STS7:00 pmSanta Rosa Sonoma County
20h 01m
3 stops
DSM5:01 pmDes Moines
$994
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Rosa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Des Moines to Santa Rosa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 12/10

5:21 am-12:27 pm

1 stop9h 06m

Santa Rosa Sonoma County

Sat 12/13

12:57 pm-10:59 pm

2 stops8h 02m

$574

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 3/4

5:15 am-12:28 pm

1 stop9h 13m

Santa Rosa Sonoma County

Wed 3/11

4:12 pm-12:04 am

1 stop5h 52m

$609

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 12/10

5:21 am-12:27 pm

1 stop9h 06m

Santa Rosa Sonoma County

Sat 12/13

12:57 pm-10:59 pm

2 stops8h 02m

$614

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Thu 3/5

5:00 am-12:28 pm

1 stop9h 28m

Santa Rosa Sonoma County

Wed 3/11

4:12 pm-12:04 am

1 stop5h 52m

$664

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 3/4

5:00 am-3:57 pm

2 stops12h 57m

Santa Rosa Sonoma County

Wed 3/11

4:12 pm-12:04 am

1 stop5h 52m

$669

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 12/10

5:00 am-12:27 pm

2 stops9h 27m

Santa Rosa Sonoma County

Sat 12/13

12:57 pm-10:59 pm

2 stops8h 02m

$674

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 3/4

5:15 am-12:28 pm

1 stop9h 13m

Santa Rosa Sonoma County

Fri 3/13

4:12 pm-12:04 am

1 stop5h 52m

$677

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Wed 12/10

5:00 am-12:27 pm

2 stops9h 27m

Santa Rosa Sonoma County

Sat 12/13

12:57 pm-10:59 pm

2 stops8h 02m

$708

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Thu 3/5

2:24 pm-12:08 pm

2 stops23h 44m

Santa Rosa Sonoma County

Thu 3/12

7:00 pm-6:02 pm

2 stops21h 02m

$719

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sun 3/8

5:21 am-10:53 pm

2 stops19h 32m

Santa Rosa Sonoma County

Sun 3/15

7:00 pm-6:02 pm

2 stops21h 02m

$849

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Francisco from

How to get the cheapest flight ticket from Des Moines to Santa Rosa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Santa Rosa?

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to Santa Rosa from Des Moines according to our data. American Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to Santa Rosa. Keep in mind that there are 5 different airlines that fly to Santa Rosa on a routine basis, so you have a few additional options to choose from.

When to book flights from Des Moines to Santa Rosa

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Rosa according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santa Rosa (DSM to STS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Rosa

Direct flights

None
There are no direct flights from Des Moines to Santa Rosa. There are no popular flight routes from Des Moines to Santa Rosa.
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  • How far is Des Moines to Santa Rosa Sonoma County by plane?

    There are 1545.9 mi between Des Moines and Santa Rosa Sonoma County. Typically, this will take 8h 49m by plane in normal conditions.

  • When did momondo last update prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

    Prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

  • How old do you have to be to fly from Des Moines Airport to Santa Rosa Sonoma County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Rosa Sonoma County Airport.

  • What documentation or ID do you need to fly to Santa Rosa Sonoma County Airport?

    The required travel and health documents for your Santa Rosa Sonoma County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Rosa Sonoma County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Des Moines to Santa Rosa?

Best airlines flying from Des Moines to Santa Rosa

Compare and see reviews for airlines that fly from Des Moines to Santa Rosa with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $573Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Fort Bragg
Mendocino
Ukiah
Little River
Point Arena

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Rosa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Santa Rosa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Santa Rosa with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Rosa from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Santa Rosa?

Once all potential Des Moines to Santa Rosa flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Santa Rosa right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Rosa from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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