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Cheap flights from Des Moines to San Francisco from $659

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Francisco departing on 10/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
5:30 am - 3:47 pmDSM-STS
12h 17m1 stop
American Airlines Logo
4:17 pm - 1:58 pmSTS-DSM
19h 41m1 stop
$659American Airlines
Find Deal
Sat, Oct 18 - Sun, Oct 19
American Airlines Logo
5:00 am - 3:47 pmDSM-STS
12h 47m2 stops
American Airlines Logo
4:17 pm - 1:58 pmSTS-DSM
19h 41m1 stop
$680American Airlines
Find Deal
Sat, Oct 18 - Sun, Oct 19
American Airlines Logo
5:30 am - 3:47 pmDSM-STS
12h 17m1 stop
American Airlines Logo
4:17 pm - 9:16 pmSTS-DSM
26h 59m1 stop
$688American Airlines
Find Deal
Sat, Oct 11 - Tue, Oct 14
American Airlines Logo
5:00 am - 3:47 pmDSM-STS
12h 47m2 stops
American Airlines Logo
12:53 pm - 1:47 pmSTS-DSM
22h 54m1 stop
$709American Airlines
Find Deal
Sat, Oct 11 - Tue, Oct 14
American Airlines Logo
5:30 am - 3:47 pmDSM-STS
12h 17m1 stop
American Airlines Logo
4:17 pm - 5:02 pmSTS-DSM
22h 45m2 stops
$716American Airlines
Find Deal
Sat, Oct 11 - Tue, Oct 14
American Airlines Logo
5:00 am - 3:47 pmDSM-STS
12h 47m2 stops
American Airlines Logo
12:53 pm - 10:45 amSTS-DSM
19h 52m2 stops
$738American Airlines
Find Deal
Sat, Oct 11 - Tue, Oct 14
American Airlines Logo
5:00 am - 3:47 pmDSM-STS
12h 47m2 stops
American Airlines Logo
4:17 pm - 5:02 pmSTS-DSM
22h 45m2 stops
$757American Airlines
Find Deal
Sat, Oct 11 - Tue, Oct 14
Alaska Airlines Logo
5:00 am - 1:36 pmDSM-STS
10h 36m2 stops
Alaska Airlines Logo
6:51 pm - 8:22 amSTS-DSM
11h 31m2 stops
$849Alaska Airlines
Find Deal
Sat, Oct 18 - Sun, Oct 19

American Airlines flights from Des Moines to Santa Rosa

Our best American Airlines deals on Des Moines to Santa Rosa flight tickets
American Airlines
Oct 18
DSM5:30 amDes Moines
12h 17m
1 stop
STS3:47 pmSanta Rosa Sonoma County
Oct 19
STS4:17 pmSanta Rosa Sonoma County
19h 41m
1 stop
DSM1:58 pmDes Moines
$659
Find similar
American Airlines
Oct 18
DSM5:00 amDes Moines
12h 47m
2 stops
STS3:47 pmSanta Rosa Sonoma County
Oct 19
STS4:17 pmSanta Rosa Sonoma County
19h 41m
1 stop
DSM1:58 pmDes Moines
$680
Find similar
American Airlines
Oct 11
DSM5:30 amDes Moines
12h 17m
1 stop
STS3:47 pmSanta Rosa Sonoma County
Oct 14
STS4:17 pmSanta Rosa Sonoma County
26h 59m
1 stop
DSM9:16 pmDes Moines
$688
Find similar

Alaska Airlines flights from Des Moines to Santa Rosa

Our best Alaska Airlines deals on Des Moines to Santa Rosa flight tickets
Alaska Airlines
Oct 18
DSM5:00 amDes Moines
10h 36m
2 stops
STS1:36 pmSanta Rosa Sonoma County
Oct 19
STS6:51 pmSanta Rosa Sonoma County
11h 31m
2 stops
DSM8:22 amDes Moines
$849
Find similar
Alaska Airlines
Sep 14
DSM5:00 amDes Moines
10h 36m
2 stops
STS1:36 pmSanta Rosa Sonoma County
Sep 16
STS7:00 amSanta Rosa Sonoma County
14h 56m
2 stops
DSM11:56 pmDes Moines
$1,289
Find similar
Alaska Airlines
Sep 9
DSM8:16 amDes Moines
14h 07m
2 stops
STS8:23 pmSanta Rosa Sonoma County
Sep 11
STS5:55 pmSanta Rosa Sonoma County
12h 30m
2 stops
DSM8:25 amDes Moines
$1,469
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Rosa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 8, 2025.
Use the filters below to find and compare flights from Des Moines to Santa Rosa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/18

5:30 am-3:47 pm

1 stop12h 17m

Santa Rosa Sonoma County

Sun 10/19

4:17 pm-1:58 pm

1 stop19h 41m

$659

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/18

5:00 am-3:47 pm

2 stops12h 47m

Santa Rosa Sonoma County

Sun 10/19

4:17 pm-1:58 pm

1 stop19h 41m

$680

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/11

5:30 am-3:47 pm

1 stop12h 17m

Santa Rosa Sonoma County

Tue 10/14

4:17 pm-9:16 pm

1 stop26h 59m

$688

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/11

5:00 am-3:47 pm

2 stops12h 47m

Santa Rosa Sonoma County

Tue 10/14

12:53 pm-1:47 pm

1 stop22h 54m

$709

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/11

5:30 am-3:47 pm

1 stop12h 17m

Santa Rosa Sonoma County

Tue 10/14

4:17 pm-5:02 pm

2 stops22h 45m

$716

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/11

5:00 am-3:47 pm

2 stops12h 47m

Santa Rosa Sonoma County

Tue 10/14

12:53 pm-10:45 am

2 stops19h 52m

$738

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/11

5:00 am-3:47 pm

2 stops12h 47m

Santa Rosa Sonoma County

Tue 10/14

4:17 pm-5:02 pm

2 stops22h 45m

$757

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 10/18

5:00 am-1:36 pm

2 stops10h 36m

Santa Rosa Sonoma County

Sun 10/19

6:51 pm-8:22 am

2 stops11h 31m

$849

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 10/14

2:40 pm-7:13 pm

3 stops30h 33m

$1,234

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 10/14

5:00 am-1:36 pm

2 stops10h 36m

$2,368

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Francisco from

How to get the cheapest flight ticket from Des Moines to Santa Rosa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Santa Rosa Sonoma County?

Alaska Airlines is the most popular carrier operating from Des Moines to Santa Rosa Sonoma County

What airlines fly to Santa Rosa?

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to Santa Rosa from Des Moines according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Santa Rosa. Keep in mind that there are 5 different airlines that fly to Santa Rosa on a routine basis, so you have a few additional options to choose from.

When to book flights from Des Moines to Santa Rosa

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Rosa according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santa Rosa (DSM to STS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Rosa

Direct flights

None
There are no direct flights from Des Moines to Santa Rosa. There are no popular flight routes from Des Moines to Santa Rosa.
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  • How far is Des Moines to Santa Rosa Sonoma County by plane?

    There are 1545.9 mi between Des Moines and Santa Rosa Sonoma County. Typically, this will take 10h 36m by plane in normal conditions.

  • When did momondo last update prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

    Prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

  • How old do you have to be to fly from Des Moines Airport to Santa Rosa Sonoma County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Rosa Sonoma County Airport.

  • What documentation or ID do you need to fly to Santa Rosa Sonoma County Airport?

    The required travel and health documents for your Santa Rosa Sonoma County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Rosa Sonoma County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Des Moines to Santa Rosa?

Best airlines flying from Des Moines to Santa Rosa

Compare and see reviews for airlines that fly from Des Moines to Santa Rosa with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $441Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

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Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Rosa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Santa Rosa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Santa Rosa with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Rosa from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Santa Rosa?

Once all potential Des Moines to Santa Rosa flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Santa Rosa right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Rosa from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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