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Cheap flights from Des Moines to San Francisco from $205

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Francisco departing on 6/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:25 am - 12:03 pm
DSM
-
STS
8h 38m
1 stop
American Airlines Logo
4:20 pm - 11:46 pm
STS
-
DSM
5h 26m
1 stop
$409American Airlines
Tue, May 26 - Tue, Jun 2
Southwest Logo
3:15 pm - 10:10 pm
DSM
-
STS
8h 55m
2 stops
Southwest Logo
6:00 am - 10:10 pm
STS
-
DSM
14h 10m
2 stops
$440Southwest
Tue, May 26 - Tue, Jun 2
Southwest Logo
3:15 pm - 10:10 pm
DSM
-
STS
8h 55m
2 stops
Southwest Logo
6:00 am - 10:20 pm
STS
-
DSM
14h 20m
2 stops
$470Southwest
Tue, May 26 - Thu, Jun 4
American Airlines Logo
5:45 am - 12:39 pm
DSM
-
STS
8h 54m
1 stop
American Airlines Logo
12:45 pm - 10:52 pm
STS
-
DSM
8h 07m
1 stop
$486American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
5:00 am - 3:50 pm
DSM
-
STS
12h 50m
2 stops
American Airlines Logo
1:03 pm - 11:46 pm
STS
-
DSM
8h 43m
1 stop
$519American Airlines
Tue, May 26 - Tue, Jun 2
American Airlines Logo
5:45 am - 12:33 pm
DSM
-
STS
8h 48m
1 stop
American Airlines Logo
1:03 pm - 11:47 pm
STS
-
DSM
8h 44m
1 stop
$534American Airlines
Sat, May 30 - Wed, Jun 3
American Airlines Logo
5:25 am - 3:50 pm
DSM
-
STS
12h 25m
2 stops
American Airlines Logo
12:43 pm - 10:52 pm
STS
-
DSM
8h 09m
1 stop
$539American Airlines
Sat, May 30 - Tue, Jun 2
American Airlines Logo
5:25 am - 12:03 pm
DSM
-
STS
8h 38m
1 stop
American Airlines Logo
1:09 pm - 11:33 pm
STS
-
DSM
8h 24m
1 stop
$544American Airlines
Tue, May 26 - Thu, Jun 4
American Airlines Logo
5:25 am - 12:03 pm
DSM
-
STS
8h 38m
1 stop
American Airlines Logo
1:03 pm - 11:33 pm
STS
-
DSM
8h 30m
1 stop
$549American Airlines
Sat, May 30 - Mon, Jun 1
American Airlines Logo
5:25 am - 12:33 pm
DSM
-
STS
9h 08m
2 stops
American Airlines Logo
1:03 pm - 11:33 pm
STS
-
DSM
8h 30m
1 stop
$554American Airlines
Sat, May 30 - Mon, Jun 1

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Alaska Airlines flights from Des Moines to Santa Rosa

Our best Alaska Airlines deals on Des Moines to Santa Rosa flight tickets
Alaska Airlines
Oct 15
DSM2:37 pmDes Moines
24h 29m
2 stops
STS1:06 pmSanta Rosa Sonoma County
Oct 18
STS3:08 pmSanta Rosa Sonoma County
25h 48m
2 stops
DSM6:56 pmDes Moines
$699
Alaska Airlines
Oct 15
DSM5:00 amDes Moines
9h 05m
2 stops
STS12:05 pmSanta Rosa Sonoma County
Oct 18
STS6:47 pmSanta Rosa Sonoma County
20h 24m
2 stops
DSM5:11 pmDes Moines
$756
Alaska Airlines
May 29
DSM2:24 pmDes Moines
11h 06m
2 stops
STS11:30 pmSanta Rosa Sonoma County
Jun 1
STS7:01 amSanta Rosa Sonoma County
15h 07m
2 stops
DSM12:08 amDes Moines
$759

American Airlines flights from Des Moines to Santa Rosa

Our best American Airlines deals on Des Moines to Santa Rosa flight tickets
American Airlines
May 26
DSM5:25 amDes Moines
8h 38m
1 stop
STS12:03 pmSanta Rosa Sonoma County
Jun 2
STS4:20 pmSanta Rosa Sonoma County
5h 26m
1 stop
DSM11:46 pmDes Moines
$409
American Airlines
Jun 16
DSM5:45 amDes Moines
8h 54m
1 stop
STS12:39 pmSanta Rosa Sonoma County
Jun 23
STS12:45 pmSanta Rosa Sonoma County
8h 07m
1 stop
DSM10:52 pmDes Moines
$486
American Airlines
May 26
DSM5:00 amDes Moines
12h 50m
2 stops
STS3:50 pmSanta Rosa Sonoma County
Jun 2
STS1:03 pmSanta Rosa Sonoma County
8h 43m
1 stop
DSM11:46 pmDes Moines
$519

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Rosa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Des Moines to Santa Rosa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 5/26

5:25 am-12:03 pm

1 stop8h 38m

Santa Rosa Sonoma County

Tue 6/2

4:20 pm-11:46 pm

1 stop5h 26m

$409

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 5/26

3:15 pm-10:10 pm

2 stops8h 55m

Santa Rosa Sonoma County

Tue 6/2

6:00 am-10:10 pm

2 stops14h 10m

$440

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 5/26

3:15 pm-10:10 pm

2 stops8h 55m

Santa Rosa Sonoma County

Thu 6/4

6:00 am-10:20 pm

2 stops14h 20m

$470

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 6/16

5:45 am-12:39 pm

1 stop8h 54m

Santa Rosa Sonoma County

Tue 6/23

12:45 pm-10:52 pm

1 stop8h 07m

$486

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 5/26

5:00 am-3:50 pm

2 stops12h 50m

Santa Rosa Sonoma County

Tue 6/2

1:03 pm-11:46 pm

1 stop8h 43m

$519

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 5/30

5:45 am-12:33 pm

1 stop8h 48m

Santa Rosa Sonoma County

Wed 6/3

1:03 pm-11:47 pm

1 stop8h 44m

$534

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 5/30

5:25 am-3:50 pm

2 stops12h 25m

Santa Rosa Sonoma County

Tue 6/2

12:43 pm-10:52 pm

1 stop8h 09m

$539

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Tue 5/26

5:25 am-12:03 pm

1 stop8h 38m

Santa Rosa Sonoma County

Thu 6/4

1:09 pm-11:33 pm

1 stop8h 24m

$544

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 5/30

5:25 am-12:03 pm

1 stop8h 38m

Santa Rosa Sonoma County

Mon 6/1

1:03 pm-11:33 pm

1 stop8h 30m

$549

Des MoinesSanta Rosa

DSM - STS

DSMSTS

Des Moines

Sat 5/30

5:25 am-12:33 pm

2 stops9h 08m

Santa Rosa Sonoma County

Mon 6/1

1:03 pm-11:33 pm

1 stop8h 30m

$554

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Santa Rosa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Santa Rosa Sonoma County?

American Airlines is the most popular carrier operating from Des Moines to Santa Rosa Sonoma County

What airlines fly to Santa Rosa?

American Airlines, United Airlines and Southwest are the top three most popular airlines that fly to Santa Rosa from Des Moines according to our data. American Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Santa Rosa. Keep in mind that there are 5 different airlines that fly to Santa Rosa on a routine basis, so you have a few additional options to choose from.

When to book flights from Des Moines to Santa Rosa

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santa Rosa according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santa Rosa (DSM to STS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santa Rosa

Fastest flight time

11h 13m

Direct flights

None
The fastest flight from Des Moines to Santa Rosa takes 11h 13m
There are no direct flights from Des Moines to Santa Rosa. There are no popular flight routes from Des Moines to Santa Rosa.
Search flight deals

Frequently asked questions about flying from Des Moines to Santa Rosa

  • How far is Des Moines to Santa Rosa Sonoma County by plane?

    There are 1545.9 mi between Des Moines and Santa Rosa Sonoma County. Typically, this will take 11h 13m by plane in normal conditions.

  • When did momondo last update prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

    Prices for flights from Des Moines Airport to Santa Rosa Sonoma County Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santa Rosa Sonoma County Airport?

  • How old do you have to be to fly from Des Moines Airport to Santa Rosa Sonoma County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santa Rosa Sonoma County Airport.

  • What documentation or ID do you need to fly to Santa Rosa Sonoma County Airport?

    The required travel and health documents for your Santa Rosa Sonoma County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Rosa Sonoma County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Des Moines to Santa Rosa?

Best airlines flying from Des Moines to Santa Rosa

Compare and see reviews for airlines that fly from Des Moines to Santa Rosa with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $573Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Fort Bragg
Mendocino
Ukiah
Little River
Point Arena

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santa Rosa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Santa Rosa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Santa Rosa with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Rosa from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Santa Rosa?

Once all potential Des Moines to Santa Rosa flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Santa Rosa right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Rosa from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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