Cheap flights from Columbus to San Diego from $121

If you are unable to visit San Diego during the month of November, then departing from Columbus during the month April is also very affordable. Most momondo users find prices during this month for around $101.

The cheapest day to depart from Columbus to San Diego is on a Saturday. Travelers who choose to depart for San Diego on a Saturday will often find tickets for as low as $395. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $564. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $446. Flights at noon are often more expensive with an average ticket price of $483.

Fly from Columbus to San Diego for the best Columbus - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $358 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Columbus for as low as $307 on momondo.

There is only 1 cabin class available to choose from on Columbus to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier and Southwest are the most popular carriers operating from Columbus to San Diego

American Airlines, Southwest and United Airlines are the top three most popular airlines that fly to San Diego from Columbus according to our data. American Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 6 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

The number of flights available between Columbus and San Diego is 1 per day as of July 2026. The most frequent departure time is 12:00PM, with 100% of daily flights leaving in the afternoon.

As of July 2026, there are 7 flights per week flying from Columbus to San Diego. The most common day of the week flights depart is Tue, with 29% of flights taking off on this day.