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Cheap flights from Tyler to San Diego from $420

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Tyler to San Diego departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
6:42 pm - 10:10 pmTYR-SAN
5h 28m1 stop
American Airlines Logo
8:49 am - 5:38 pmSAN-TYR
6h 49m1 stop
$420American Airlines
Find Deal
Sat, Feb 28 - Tue, Mar 3
American Airlines Logo
10:26 am - 5:50 pmTYR-SAN
9h 24m2 stops
American Airlines Logo
8:49 am - 5:38 pmSAN-TYR
6h 49m1 stop
$426American Airlines
Find Deal
Sat, Feb 28 - Tue, Mar 3
American Airlines Logo
10:26 am - 5:50 pmTYR-SAN
9h 24m2 stops
American Airlines Logo
6:35 am - 5:38 pmSAN-TYR
9h 03m2 stops
$431American Airlines
Find Deal
Sat, Feb 28 - Tue, Mar 3
American Airlines Logo
10:19 am - 3:53 pmTYR-SAN
7h 34m1 stop
American Airlines Logo
3:01 pm - 10:42 pmSAN-TYR
5h 41m1 stop
$455American Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23
American Airlines Logo
5:25 am - 11:57 amTYR-SAN
8h 32m2 stops
American Airlines Logo
12:38 pm - 10:42 pmSAN-TYR
8h 04m1 stop
$461American Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23
American Airlines Logo
5:25 am - 11:57 amTYR-SAN
8h 32m2 stops
American Airlines Logo
1:06 pm - 10:42 pmSAN-TYR
7h 36m2 stops
$466American Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23
American Airlines Logo
5:25 am - 8:24 amTYR-SAN
4h 59m1 stop
American Airlines Logo
12:38 pm - 10:42 pmSAN-TYR
8h 04m1 stop
$522American Airlines
Find Deal
Thu, Sep 18 - Mon, Sep 22
American Airlines Logo
4:58 pm - 9:52 pmTYR-SAN
6h 54m2 stops
American Airlines Logo
8:18 am - 4:27 pmSAN-TYR
6h 09m1 stop
$528American Airlines
Find Deal
Thu, Sep 18 - Mon, Sep 22
American Airlines Logo
4:58 pm - 9:52 pmTYR-SAN
6h 54m2 stops
American Airlines Logo
9:45 am - 10:42 pmSAN-TYR
10h 57m2 stops
$533American Airlines
Find Deal
Thu, Sep 18 - Mon, Sep 22

American Airlines flights from Tyler to San Diego

Our best American Airlines deals on Tyler to San Diego flight tickets
American Airlines
Feb 28
TYR6:42 pmTyler Pounds Field
5h 28m
1 stop
SAN10:10 pmSan Diego
Mar 3
SAN8:49 amSan Diego
6h 49m
1 stop
TYR5:38 pmTyler Pounds Field
$420
Find similar
American Airlines
Feb 28
TYR10:26 amTyler Pounds Field
9h 24m
2 stops
SAN5:50 pmSan Diego
Mar 3
SAN8:49 amSan Diego
6h 49m
1 stop
TYR5:38 pmTyler Pounds Field
$426
Find similar
American Airlines
Feb 28
TYR10:26 amTyler Pounds Field
9h 24m
2 stops
SAN5:50 pmSan Diego
Mar 3
SAN6:35 amSan Diego
9h 03m
2 stops
TYR5:38 pmTyler Pounds Field
$431
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Tyler to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Tyler to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Sat 2/28

6:42 pm-10:10 pm

1 stop5h 28m

San Diego

Tue 3/3

8:49 am-5:38 pm

1 stop6h 49m

$420

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Sat 2/28

10:26 am-5:50 pm

2 stops9h 24m

San Diego

Tue 3/3

8:49 am-5:38 pm

1 stop6h 49m

$426

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Sat 2/28

10:26 am-5:50 pm

2 stops9h 24m

San Diego

Tue 3/3

6:35 am-5:38 pm

2 stops9h 03m

$431

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Fri 9/19

10:19 am-3:53 pm

1 stop7h 34m

San Diego

Tue 9/23

3:01 pm-10:42 pm

1 stop5h 41m

$455

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Fri 9/19

5:25 am-11:57 am

2 stops8h 32m

San Diego

Tue 9/23

12:38 pm-10:42 pm

1 stop8h 04m

$461

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Fri 9/19

5:25 am-11:57 am

2 stops8h 32m

San Diego

Tue 9/23

1:06 pm-10:42 pm

2 stops7h 36m

$466

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Thu 9/18

5:25 am-8:24 am

1 stop4h 59m

San Diego

Mon 9/22

12:38 pm-10:42 pm

1 stop8h 04m

$522

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Thu 9/18

4:58 pm-9:52 pm

2 stops6h 54m

San Diego

Mon 9/22

8:18 am-4:27 pm

1 stop6h 09m

$528

TylerSan Diego

TYR - SAN

TYRSAN

Tyler Pounds Field

Thu 9/18

4:58 pm-9:52 pm

2 stops6h 54m

San Diego

Mon 9/22

9:45 am-10:42 pm

2 stops10h 57m

$533

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Diego from

How to get the cheapest flight ticket from Tyler to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Tyler to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $524. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $622. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the morning when flights can be purchased for as low as $468. Flights in the afternoon are often more expensive with an average ticket price of $585.

When to book flights from Tyler to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Tyler to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tyler to San Diego (TYR to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tyler to San Diego

Direct flights

None
There are no direct flights from Tyler to San Diego. There are no popular flight routes from Tyler to San Diego.
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  • How far is Tyler Pounds Field to San Diego by plane?

    There are 1270.3 mi between Tyler Pounds Field and San Diego. In terms of flight time, this usually takes a little over 4h 59m.

  • When did momondo last update prices for flights from Tyler Pounds Field Airport to San Diego Airport?

    Prices for flights from Tyler Pounds Field Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Tyler Pounds Field Airport to San Diego Airport?

  • How old do you have to be to fly from Tyler Pounds Field Airport to San Diego Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Tyler Pounds Field Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Tyler to San Diego?

Best airlines flying from Tyler to San Diego

Compare and see reviews for airlines that fly from Tyler to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $330Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Imperial Beach
Poway
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Tyler to San Diego?

Finding the right flight to San Diego from Tyler is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Tyler to San Diego with flexible booking policies on momondo?

All flight searches from Tyler to San Diego on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Tyler to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Tyler to San Diego.

I’m not ready to book a flight from Tyler to San Diego right now. Can momondo alert me if prices change?

Price alerts on flights to San Diego from Tyler are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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