Cheap flights from St. Louis to Los Angeles from $162

The month of September is, on average, the cheapest month to fly to Los Angeles from St. Louis, with most prices found around $310. If you aren’t able to travel during the month of September, then book flights to Los Angeles from St. Louis during October instead. Flights to Los Angeles in October, while not as cheap as those in September, still average around $318.

Our data shows that Thursday is the least expensive day to fly to Los Angeles. Tickets to fly out on this day can be as low as $416. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Los Angeles on Sunday is $536.

Our most recent data shows that the best time of day to fly to Los Angeles is in the afternoon. Flights from St. Louis to Los Angeles during this time can be as low as $335. In the morning is when there is more demand to fly to Los Angeles, so prices are often more expensive at around $504 per ticket.

Fly from Lambert-St Louis to Los Angeles Los Angeles for the best Lambert-St Louis - Los Angeles Los Angeles flight prices

You are more likely to see cheaper flights to Los Angeles from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Los Angeles for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Los Angeles from St. Louis for as low as $289 on momondo.

There are 4 cabin classes available to choose from on Lambert-St Louis to Los Angeles Los Angeles flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between St. Louis to Los Angeles.

As of March 2026, prices for St. Louis to Los Angeles flights are approximately 18% more expensive when compared to flights at the same time last year.

Alaska Airlines and Southwest are the most popular carriers operating from Lambert-St Louis to Los Angeles Los Angeles

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to Los Angeles from St. Louis according to our data. Southwest is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Los Angeles. Keep in mind that there are 8 different airlines that fly to Los Angeles on a routine basis, so you have a few additional options to choose from.

Salt Lake City (SLC) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Salt Lake City (SLC) offer the lowest average round-trip price of $392.

Flights connecting via Salt Lake City (SLC) have the shortest average one-way travel time: 6h 10m.

Salt Lake City (SLC) has the shortest average layover time for this route: 0h 56m.

8 flights are operational daily from St. Louis to Los Angeles as of March 2026. The most popular departure time for this route is 6:00AM, with 94% of flights per day taking off at noon.

The number of flights available between St. Louis and Los Angeles is 62 per week as of March 2026. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.