Cheap flights from South Carolina to San Francisco from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to San Francisco departing on 6/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
6:20 am - 11:51 am
CHS
-
SFO
8h 31m
1 stop
Breeze Airways Logo
11:54 am - 9:34 pm
SFO
-
CHS
6h 40m
1 stop
$257Breeze Airways
Wed, Oct 21 - Fri, Oct 30
Breeze Airways Logo
6:10 am - 11:09 am
CHS
-
SFO
7h 59m
1 stop
Breeze Airways Logo
11:54 am - 9:34 pm
SFO
-
CHS
6h 40m
1 stop
$260Breeze Airways
Mon, Oct 19 - Fri, Oct 30
Frontier Logo
2:20 pm - 8:49 am
CLT
-
SFO
21h 29m
1 stop
Frontier Logo
12:52 pm - 6:18 pm
SFO
-
CLT
26h 26m
1 stop
$290Frontier
Fri, May 29 - Mon, Jun 1
Frontier Logo
7:14 pm - 8:01 am
CLT
-
SFO
15h 47m
1 stop
Frontier Logo
12:52 pm - 6:18 pm
SFO
-
CLT
26h 26m
1 stop
$300Frontier
Thu, May 28 - Mon, Jun 1
Delta Logo
10:10 am - 4:55 pm
CAE
-
SFO
9h 45m
1 stop
Delta Logo
11:45 pm - 9:25 am
SFO
-
CAE
6h 40m
1 stop
$301Delta
Sat, Sep 19 - Tue, Sep 22
Delta Logo
5:50 pm - 12:46 am
CAE
-
SFO
9h 56m
1 stop
Delta Logo
10:45 pm - 9:22 am
SFO
-
CAE
7h 37m
1 stop
$329Delta
Fri, Jun 5 - Sat, Jul 11
United Airlines Logo
7:35 pm - 1:16 am
CAE
-
SFO
8h 41m
1 stop
United Airlines Logo
11:30 pm - 10:10 am
SFO
-
CAE
7h 40m
1 stop
$357United Airlines
Fri, Sep 11 - Mon, Sep 14
American Airlines Logo
7:22 pm - 12:48 am
CAE
-
SFO
8h 26m
1 stop
American Airlines Logo
5:29 am - 6:48 pm
SFO
-
CAE
10h 19m
1 stop
$367American Airlines
Fri, Jun 5 - Sat, Jul 11
American Airlines Logo
6:03 pm - 10:48 pm
CAE
-
SFO
7h 45m
1 stop
American Airlines Logo
11:49 pm - 10:44 am
SFO
-
CAE
7h 55m
1 stop
$384American Airlines
Tue, Jul 21 - Sat, Aug 1
United Airlines Logo
7:40 pm - 1:15 am
GSP
-
SFO
8h 35m
1 stop
United Airlines Logo
11:30 pm - 9:55 am
SFO
-
GSP
7h 25m
1 stop
$408United Airlines
Wed, Jun 3 - Sat, Jun 6

Breeze Airways flights from South Carolina to San Francisco

Our best Breeze Airways deals on South Carolina to San Francisco flight tickets
Breeze Airways
Oct 21
CHS6:20 amCharleston
8h 31m
1 stop
SFO11:51 amSan Francisco
Oct 30
SFO11:54 amSan Francisco
6h 40m
1 stop
CHS9:34 pmCharleston
$257
Breeze Airways
Oct 19
CHS6:10 amCharleston
7h 59m
1 stop
SFO11:09 amSan Francisco
Oct 30
SFO11:54 amSan Francisco
6h 40m
1 stop
CHS9:34 pmCharleston
$260
Breeze Airways
Oct 23
CHS6:10 amCharleston
7h 59m
1 stop
SFO11:09 amSan Francisco
Oct 30
SFO11:54 amSan Francisco
6h 40m
1 stop
CHS9:34 pmCharleston
$268

United Airlines flights from South Carolina to San Francisco

Our best United Airlines deals on South Carolina to San Francisco flight tickets
United Airlines
Sep 25
CHS2:46 pmCharleston
8h 44m
1 stop
SFO8:30 pmSan Francisco
Sep 28
SFO11:30 pmSan Francisco
7h 57m
1 stop
CHS10:27 amCharleston
$318
United Airlines
Jun 13
CHS7:47 pmCharleston
8h 28m
1 stop
SFO1:15 amSan Francisco
Jun 19
SFO11:30 pmSan Francisco
8h 05m
1 stop
CHS10:35 amCharleston
$355
United Airlines
Sep 11
CAE7:35 pmColumbia Metropolitan
8h 41m
1 stop
SFO1:16 amSan Francisco
Sep 14
SFO11:30 pmSan Francisco
7h 40m
1 stop
CAE10:10 amColumbia Metropolitan
$357

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Wed 10/21

6:20 am-11:51 am

1 stop8h 31m

San Francisco

Fri 10/30

11:54 am-9:34 pm

1 stop6h 40m

$257
Quickest round-trip

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Mon 10/19

6:10 am-11:09 am

1 stop7h 59m

San Francisco

Fri 10/30

11:54 am-9:34 pm

1 stop6h 40m

$260

CharlotteSan Francisco

CLT - SFO

CLTSFO

Charlotte Douglas

Fri 5/29

2:20 pm-8:49 am

1 stop21h 29m

San Francisco

Mon 6/1

12:52 pm-6:18 pm

1 stop26h 26m

$290

CharlotteSan Francisco

CLT - SFO

CLTSFO

Charlotte Douglas

Thu 5/28

7:14 pm-8:01 am

1 stop15h 47m

San Francisco

Mon 6/1

12:52 pm-6:18 pm

1 stop26h 26m

$300

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Sat 9/19

10:10 am-4:55 pm

1 stop9h 45m

San Francisco

Tue 9/22

11:45 pm-9:25 am

1 stop6h 40m

$301

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 6/5

5:50 pm-12:46 am

1 stop9h 56m

San Francisco

Sat 7/11

10:45 pm-9:22 am

1 stop7h 37m

$329

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 9/11

7:35 pm-1:16 am

1 stop8h 41m

San Francisco

Mon 9/14

11:30 pm-10:10 am

1 stop7h 40m

$357

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 6/5

7:22 pm-12:48 am

1 stop8h 26m

San Francisco

Sat 7/11

5:29 am-6:48 pm

1 stop10h 19m

$367

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Tue 7/21

6:03 pm-10:48 pm

1 stop7h 45m

San Francisco

Sat 8/1

11:49 pm-10:44 am

1 stop7h 55m

$384

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 6/3

7:40 pm-1:15 am

1 stop8h 35m

San Francisco

Sat 6/6

11:30 pm-9:55 am

1 stop7h 25m

$408

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from South Carolina to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of May, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $92.

What is the cheapest South Carolina to San Francisco flight route?

Fly from Charleston to San Francisco for the best South Carolina - San Francisco flight prices

How far in advance should I book a flight from South Carolina to San Francisco?

You are more likely to see cheaper flights to San Francisco from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $385 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from South Carolina for as low as $219 on momondo.

Cheap South Carolina to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to San Francisco

Fastest flight time

5h 25m

Direct flights

Every day

Airports in San Francisco

1 airport
The fastest flight from South Carolina to San Francisco takes 5h 25m
Direct flights go from South Carolina to San Francisco every day.
There is 1 airport in San Francisco. From South Carolina there are direct flights to San Francisco (SFO).

Frequently asked questions about flying from South Carolina to San Francisco

  • When did momondo last update prices for flights from South Carolina to San Francisco Airport?

    Prices for flights from South Carolina to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to San Francisco Airport?

  • How old do you have to be to fly from South Carolina to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from South Carolina to San Francisco?

Best airlines flying from South Carolina to San Francisco

Compare and see reviews for airlines that fly from South Carolina to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $131Free CancellationRating
8.1
284 reviews
Search Breeze Airways flights
DeltaPriceFrom $199Free CancellationRating
7.9
8,452 reviews
Search Delta flights
American AirlinesPriceFrom $246Free CancellationRating
7.1
11,663 reviews
Search American Airlines flights
United AirlinesPriceFrom $256Free CancellationRating
7.4
9,717 reviews
Search United Airlines flights
JetBluePriceFrom $276Free CancellationRating
7.1
2,974 reviews
Search JetBlue flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,299 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Walnut Creek
Bodega Bay
Hayward
Roseville
Santa Clara
Berkeley
Fremont
Vallejo
Big Sur
Sunnyvale
Calistoga
South San Francisco
Salinas
Daly City
Milpitas
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to San Francisco for you.

Can I find flights from South Carolina to San Francisco with flexible booking policies on momondo?

All flight searches from South Carolina to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to San Francisco.

I’m not ready to book a flight from South Carolina to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Sun 6/14
Sun 6/21

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