Cheap flights from South Carolina to San Antonio from $69

If you aren’t able to travel during the month of September, then book flights to San Antonio from South Carolina during January instead. Flights to San Antonio in January, while not as cheap as those in September, still average around $344.

You are more likely to see cheaper flights to San Antonio from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $409 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from South Carolina for as low as $329 on momondo.

Frontier, Spirit Airlines, and Delta are the most popular carriers operating from South Carolina to San Antonio

Delta, American Airlines and Southwest are the top three most popular airlines that fly to San Antonio from South Carolina according to our data. Delta is the first choice among our users, with 43% of people opting to fly with this airline when traveling to San Antonio. Keep in mind that there are 5 different airlines that fly to San Antonio on a routine basis, so you have a few additional options to choose from.

As of March 2026, there are 29 flights per week flying from South Carolina to San Antonio. The most common day of the week flights depart is Mon, with 21% of flights taking off on this day.

Flight times vary depending on what airport in South Carolina you fly out of and what airport in San Antonio you fly into. For example, flying from Charleston to Austin takes 2h 40m on average. On the other hand, flying from Greenville to Austin takes 4h 15m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.