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Cheap flights from Sicily to San Francisco from $388

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sicily to San Francisco departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Sicily to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
ITA Airways Logo
7:05 pm - 1:15 pm
PMO
-
SFO
27h 10m
1 stop
ITA Airways Logo
12:05 pm - 3:25 pm
SFO
-
PMO
18h 20m
2 stops
$560ITA Airways
Thu, Apr 23 - Wed, May 6
ITA Airways Logo
2:25 pm - 1:05 pm
PMO
-
SFO
31h 40m
1 stop
ITA Airways Logo
4:05 pm - 6:25 pm
SFO
-
PMO
18h 20m
1 stop
$562ITA Airways
Sun, Mar 1 - Mon, Mar 9
ITA Airways Logo
6:00 am - 5:12 pm
CTA
-
SFO
20h 12m
2 stops
ITA Airways Logo
8:49 am - 2:40 pm
SFO
-
CTA
20h 51m
2 stops
$563ITA Airways
Wed, Apr 8 - Mon, Apr 13
ITA Airways Logo
6:00 am - 5:12 pm
CTA
-
SFO
20h 12m
2 stops
ITA Airways Logo
10:10 am - 3:45 pm
SFO
-
CTA
20h 35m
2 stops
$573ITA Airways
Wed, Apr 8 - Wed, Apr 15
ITA Airways Logo
6:00 am - 1:25 pm
CTA
-
SFO
16h 25m
1 stop
ITA Airways Logo
12:00 pm - 3:45 pm
SFO
-
CTA
18h 45m
2 stops
$574ITA Airways
Wed, Apr 8 - Wed, Apr 15
ITA Airways Logo
6:00 am - 1:25 pm
CTA
-
SFO
16h 25m
1 stop
ITA Airways Logo
3:25 pm - 3:45 pm
SFO
-
CTA
15h 20m
1 stop
$581ITA Airways
Wed, Apr 8 - Wed, Apr 15
Multiple Airlines Logo
9:10 am - 11:45 am
PMO
-
SFO
35h 35m
1 stop
Multiple Airlines Logo
8:10 pm - 12:05 pm
SFO
-
PMO
30h 55m
1 stop
$605Multiple Airlines
Thu, Apr 23 - Wed, May 6
American Airlines Logo
12:05 pm - 1:14 pm
PMO
-
SFO
34h 09m
2 stops
American Airlines Logo
2:59 pm - 6:40 pm
SFO
-
PMO
18h 41m
2 stops
$615American Airlines
Thu, Apr 23 - Sun, Apr 26
British Airways Logo
8:30 pm - 3:00 pm
PMO
-
SFO
27h 30m
1 stop
British Airways Logo
11:35 pm - 10:45 am
SFO
-
PMO
51h 10m
2 stops
$635British Airways
Sun, Mar 1 - Mon, Mar 9
Multiple Airlines Logo
6:10 am - 11:19 pm
REG
-
SFO
25h 09m
2 stops
Multiple Airlines Logo
7:00 am - 2:30 pm
SFO
-
REG
23h 30m
2 stops
$790Multiple Airlines
Wed, Mar 18 - Wed, Mar 25

ITA Airways flights from Sicily to San Francisco

Our best ITA Airways deals on Sicily to San Francisco flight tickets
ITA Airways
Apr 23
PMO7:05 pmPalermo Punta Raisi
27h 10m
1 stop
SFO1:15 pmSan Francisco
May 6
SFO12:05 pmSan Francisco
18h 20m
2 stops
PMO3:25 pmPalermo Punta Raisi
$560
ITA Airways
Mar 1
PMO2:25 pmPalermo Punta Raisi
31h 40m
1 stop
SFO1:05 pmSan Francisco
Mar 9
SFO4:05 pmSan Francisco
18h 20m
1 stop
PMO6:25 pmPalermo Punta Raisi
$562
ITA Airways
Apr 8
CTA6:00 amCatania Fontanarossa
20h 12m
2 stops
SFO5:12 pmSan Francisco
Apr 13
SFO8:49 amSan Francisco
20h 51m
2 stops
CTA2:40 pmCatania Fontanarossa
$563

Turkish Airlines flights from Sicily to San Francisco

Our best Turkish Airlines deals on Sicily to San Francisco flight tickets
Turkish Airlines
Mar 19
CTA7:25 pmCatania Fontanarossa
30h 20m
1 stop
SFO5:45 pmSan Francisco
Mar 26
SFO7:50 pmSan Francisco
28h 45m
1 stop
CTA8:35 amCatania Fontanarossa
$740
Turkish Airlines
Apr 6
CTA9:25 amCatania Fontanarossa
34h 25m
1 stop
SFO10:50 amSan Francisco
Apr 14
SFO6:45 pmSan Francisco
38h 40m
1 stop
CTA6:25 pmCatania Fontanarossa
$775
Turkish Airlines
Jul 11
PMO7:35 pmPalermo Punta Raisi
24h 15m
1 stop
SFO10:50 amSan Francisco
Jul 31
SFO12:55 pmSan Francisco
20h 40m
1 stop
PMO6:35 pmPalermo Punta Raisi
$1,059

momondo Fare Finder

 
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:05 pm-1:15 pm

1 stop27h 10m

San Francisco

Wed 5/6

12:05 pm-3:25 pm

2 stops18h 20m

$560

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 3/1

2:25 pm-1:05 pm

1 stop31h 40m

San Francisco

Mon 3/9

4:05 pm-6:25 pm

1 stop18h 20m

$562

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Wed 4/8

6:00 am-5:12 pm

2 stops20h 12m

San Francisco

Mon 4/13

8:49 am-2:40 pm

2 stops20h 51m

$563

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Wed 4/8

6:00 am-5:12 pm

2 stops20h 12m

San Francisco

Wed 4/15

10:10 am-3:45 pm

2 stops20h 35m

$573

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Wed 4/8

6:00 am-1:25 pm

1 stop16h 25m

San Francisco

Wed 4/15

12:00 pm-3:45 pm

2 stops18h 45m

$574

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Wed 4/8

6:00 am-1:25 pm

1 stop16h 25m

San Francisco

Wed 4/15

3:25 pm-3:45 pm

1 stop15h 20m

$581

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

9:10 am-11:45 am

1 stop35h 35m

San Francisco

Wed 5/6

8:10 pm-12:05 pm

1 stop30h 55m

$605

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

12:05 pm-1:14 pm

2 stops34h 09m

San Francisco

Sun 4/26

2:59 pm-6:40 pm

2 stops18h 41m

$615

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 3/1

8:30 pm-3:00 pm

1 stop27h 30m

San Francisco

Mon 3/9

11:35 pm-10:45 am

2 stops51h 10m

$635

Reggio CalabriaSan Francisco

REG - SFO

REGSFO

Reggio Calabria Tito Menniti

Wed 3/18

6:10 am-11:19 pm

2 stops25h 09m

San Francisco

Wed 3/25

7:00 am-2:30 pm

2 stops23h 30m

$790

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Sicily to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Sicily to San Francisco flights?

You could potentially save up to 13% on your flight if you consider stops on a Sicily to San Francisco flight.

Cheap Sicily to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sicily to San Francisco

Fastest flight time

21h 19m

Direct flights

None
The fastest flight from Sicily to San Francisco takes 21h 19m
There are no direct flights from Sicily to San Francisco. There are no popular flight routes from Sicily to San Francisco.
Search flight deals

  • When did momondo last update prices for flights from Sicily to San Francisco Airport?

    Prices for flights from Sicily to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Sicily to San Francisco Airport?

  • How old do you have to be to fly from Sicily to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Sicily to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Sicily to San Francisco

Compare and see reviews for airlines that fly from Sicily to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $710Free CancellationRating
6.8
7,759 reviews
Search Lufthansa flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Santa Clara
Walnut Creek
Berkeley
Big Sur
Fremont
Half Moon Bay
Daly City
Salinas
Vallejo
Sunnyvale
Livermore
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Sicily to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Sicily to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Sicily to San Francisco with flexible booking policies on momondo?

Flights from Sicily to San Francisco with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Sicily to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Sicily to San Francisco.

I’m not ready to book a flight from Sicily to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Sicily and alert you when they change.

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