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Cheap flights from Sicily to San Francisco from $427

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sicily to San Francisco departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Sicily to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
ITA Airways Logo
6:10 am - 1:05 pm
PMO
-
SFO
15h 55m
1 stop
ITA Airways Logo
3:05 pm - 2:20 pm
SFO
-
PMO
14h 15m
1 stop
$570ITA Airways
Tue, Nov 17 - Tue, Nov 24
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
3:15 pm - 7:45 pm
SFO
-
PMO
19h 30m
1 stop
$589ITA Airways
Thu, Sep 10 - Sun, Sep 20
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
3:15 pm - 9:05 pm
SFO
-
PMO
20h 50m
1 stop
$591ITA Airways
Tue, Sep 8 - Mon, Sep 21
Scandinavian Airlines Logo
6:50 pm - 2:40 pm
PMO
-
SFO
28h 50m
1 stop
Scandinavian Airlines Logo
6:00 am - 5:10 pm
SFO
-
PMO
26h 10m
2 stops
$603Scandinavian Airlines
Wed, Sep 9 - Fri, Sep 18
ITA Airways Logo
4:10 pm - 1:05 pm
PMO
-
SFO
29h 55m
1 stop
ITA Airways Logo
3:05 pm - 10:45 am
SFO
-
PMO
34h 40m
2 stops
$607ITA Airways
Fri, Nov 20 - Thu, Nov 26
Scandinavian Airlines Logo
6:50 pm - 2:40 pm
PMO
-
SFO
28h 50m
1 stop
Scandinavian Airlines Logo
5:38 pm - 6:00 pm
SFO
-
PMO
39h 22m
2 stops
$609Scandinavian Airlines
Wed, Sep 9 - Mon, Sep 21
ITA Airways Logo
8:25 pm - 1:05 pm
PMO
-
SFO
25h 40m
2 stops
ITA Airways Logo
3:05 pm - 10:45 am
SFO
-
PMO
34h 40m
2 stops
$624ITA Airways
Fri, Nov 20 - Thu, Nov 26
Air France Logo
7:30 pm - 12:50 pm
CTA
-
SFO
26h 20m
1 stop
Air France Logo
3:05 pm - 9:55 am
SFO
-
CTA
33h 50m
1 stop
$837Air France
Thu, Jul 16 - Mon, Jul 20
United Airlines Logo
6:25 am - 9:30 am
REG
-
SFO
36h 05m
2 stops
United Airlines Logo
11:30 pm - 2:30 pm
SFO
-
REG
30h 00m
2 stops
$974United Airlines
Tue, Aug 11 - Tue, Aug 18
United Airlines Logo
6:25 am - 6:24 pm
REG
-
SFO
20h 59m
2 stops
United Airlines Logo
6:45 am - 2:30 pm
SFO
-
REG
22h 45m
2 stops
$976United Airlines
Wed, Sep 30 - Sun, Oct 4

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ITA Airways flights from Sicily to San Francisco

Our best ITA Airways deals on Sicily to San Francisco flight tickets
ITA Airways
Nov 17
PMO6:10 amPalermo Punta Raisi
15h 55m
1 stop
SFO1:05 pmSan Francisco
Nov 24
SFO3:05 pmSan Francisco
14h 15m
1 stop
PMO2:20 pmPalermo Punta Raisi
$570
ITA Airways
Sep 10
PMO6:10 amPalermo Punta Raisi
16h 05m
1 stop
SFO1:15 pmSan Francisco
Sep 20
SFO3:15 pmSan Francisco
19h 30m
1 stop
PMO7:45 pmPalermo Punta Raisi
$589
ITA Airways
Sep 8
PMO6:10 amPalermo Punta Raisi
16h 05m
1 stop
SFO1:15 pmSan Francisco
Sep 21
SFO3:15 pmSan Francisco
20h 50m
1 stop
PMO9:05 pmPalermo Punta Raisi
$591

British Airways flights from Sicily to San Francisco

Our best British Airways deals on Sicily to San Francisco flight tickets
British Airways
Nov 19
PMO12:50 pmPalermo Punta Raisi
35h 05m
1 stop
SFO2:55 pmSan Francisco
Nov 27
SFO11:59 pmSan Francisco
27h 01m
2 stops
PMO12:00 pmPalermo Punta Raisi
$741
British Airways
Sep 14
PMO7:50 pmPalermo Punta Raisi
27h 00m
1 stop
SFO1:50 pmSan Francisco
Sep 22
SFO1:27 pmSan Francisco
36h 43m
2 stops
PMO11:10 amPalermo Punta Raisi
$742
British Airways
Nov 19
PMO12:50 pmPalermo Punta Raisi
38h 34m
2 stops
SFO6:24 pmSan Francisco
Nov 27
SFO11:59 pmSan Francisco
27h 01m
2 stops
PMO12:00 pmPalermo Punta Raisi
$746

momondo Fare Finder

 
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 11/17

6:10 am-1:05 pm

1 stop15h 55m

San Francisco

Tue 11/24

3:05 pm-2:20 pm

1 stop14h 15m

$570

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 9/10

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sun 9/20

3:15 pm-7:45 pm

1 stop19h 30m

$589

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 9/8

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Mon 9/21

3:15 pm-9:05 pm

1 stop20h 50m

$591

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 9/9

6:50 pm-2:40 pm

1 stop28h 50m

San Francisco

Fri 9/18

6:00 am-5:10 pm

2 stops26h 10m

$603

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/20

4:10 pm-1:05 pm

1 stop29h 55m

San Francisco

Thu 11/26

3:05 pm-10:45 am

2 stops34h 40m

$607

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 9/9

6:50 pm-2:40 pm

1 stop28h 50m

San Francisco

Mon 9/21

5:38 pm-6:00 pm

2 stops39h 22m

$609

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/20

8:25 pm-1:05 pm

2 stops25h 40m

San Francisco

Thu 11/26

3:05 pm-10:45 am

2 stops34h 40m

$624

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Thu 7/16

7:30 pm-12:50 pm

1 stop26h 20m

San Francisco

Mon 7/20

3:05 pm-9:55 am

1 stop33h 50m

$837

Reggio CalabriaSan Francisco

REG - SFO

REGSFO

Reggio Calabria Tito Menniti

Tue 8/11

6:25 am-9:30 am

2 stops36h 05m

San Francisco

Tue 8/18

11:30 pm-2:30 pm

2 stops30h 00m

$974

Reggio CalabriaSan Francisco

REG - SFO

REGSFO

Reggio Calabria Tito Menniti

Wed 9/30

6:25 am-6:24 pm

2 stops20h 59m

San Francisco

Sun 10/4

6:45 am-2:30 pm

2 stops22h 45m

$976

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Sicily to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of January, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $537.

Can stopping save me money on Sicily to San Francisco flights?

You could potentially save up to 10% on your flight if you consider stops on a Sicily to San Francisco flight.

Cheap Sicily to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sicily to San Francisco

Fastest flight time

15h 50m

Direct flights

None
The fastest flight from Sicily to San Francisco takes 15h 50m
There are no direct flights from Sicily to San Francisco. There are no popular flight routes from Sicily to San Francisco.
Search flight deals

Frequently asked questions about flying from Sicily to San Francisco

  • When did momondo last update prices for flights from Sicily to San Francisco Airport?

    Prices for flights from Sicily to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Sicily to San Francisco Airport?

  • How old do you have to be to fly from Sicily to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Sicily to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Sicily to San Francisco

Compare and see reviews for airlines that fly from Sicily to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
LufthansaPriceFrom $710Free CancellationRating
6.8
8,109 reviews
Search Lufthansa flights
ITA AirwaysPriceFrom $714Free CancellationRating
6.7
1,269 reviews
Search ITA Airways flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Bodega Bay
South San Francisco
Sonoma
Fremont
Hayward
Roseville
Walnut Creek
Santa Clara
Berkeley
Vallejo
Salinas
Sunnyvale
Big Sur
Burlingame
Daly City
Milpitas
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Sicily to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Sicily to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Sicily to San Francisco with flexible booking policies on momondo?

Flights from Sicily to San Francisco with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Sicily to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Sicily to San Francisco.

I’m not ready to book a flight from Sicily to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Sicily and alert you when they change.

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