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Cheap flights from Santa Ana, California to Buffalo from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Buffalo departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
9:10 pm - 9:44 am
SNA
-
BUF
9h 34m
1 stop
Delta Logo
7:55 pm - 11:15 am
BUF
-
SNA
18h 20m
1 stop
$399Delta
mar., mai 26 - ven., mai 29
Delta Logo
11:53 am - 11:59 pm
SNA
-
BUF
9h 06m
1 stop
Delta Logo
6:15 am - 12:40 pm
BUF
-
SNA
9h 25m
1 stop
$402Delta
mer., mai 20 - mer., mai 27
Delta Logo
9:10 pm - 9:44 am
SNA
-
BUF
9h 34m
1 stop
Delta Logo
5:26 pm - 10:29 pm
BUF
-
SNA
8h 03m
1 stop
$404Delta
mar., mai 26 - sam., mai 30
Delta Logo
8:00 am - 11:59 pm
SNA
-
BUF
12h 59m
2 stops
Delta Logo
6:15 am - 12:40 pm
BUF
-
SNA
9h 25m
1 stop
$407Delta
mer., mai 20 - mer., mai 27
United Airlines Logo
6:50 am - 9:08 pm
SNA
-
BUF
11h 18m
2 stops
United Airlines Logo
5:52 pm - 10:14 pm
BUF
-
SNA
7h 22m
1 stop
$409United Airlines
sam., sept. 19 - mar., sept. 22
Delta Logo
8:00 am - 11:59 pm
SNA
-
BUF
12h 59m
2 stops
Delta Logo
12:04 pm - 9:54 pm
BUF
-
SNA
12h 50m
2 stops
$413Delta
mer., mai 20 - mer., mai 27
American Airlines Logo
10:29 am - 11:10 pm
SNA
-
BUF
9h 41m
2 stops
American Airlines Logo
2:46 pm - 9:37 pm
BUF
-
SNA
9h 51m
2 stops
$418American Airlines
sam., sept. 19 - mar., sept. 22
American Airlines Logo
12:01 pm - 11:10 pm
SNA
-
BUF
8h 09m
1 stop
American Airlines Logo
1:43 pm - 8:01 pm
BUF
-
SNA
9h 18m
1 stop
$443American Airlines
sam., sept. 12 - sam., sept. 19
United Airlines Logo
6:50 am - 9:08 pm
SNA
-
BUF
11h 18m
2 stops
United Airlines Logo
7:00 am - 11:33 am
BUF
-
SNA
7h 33m
1 stop
$448United Airlines
sam., sept. 12 - sam., sept. 19
American Airlines Logo
10:29 am - 11:10 pm
SNA
-
BUF
9h 41m
2 stops
American Airlines Logo
2:36 pm - 9:37 pm
BUF
-
SNA
10h 01m
2 stops
$454American Airlines
sam., sept. 12 - sam., sept. 19

Southwest flights from Santa Ana, California to Buffalo

Our best Southwest deals on Santa Ana, California to Buffalo flight tickets
Southwest
Sep 23
SNA8:45 amSanta Ana J. Wayne/Orange Cnty
9h 20m
2 stops
BUF9:05 pmBuffalo
Sep 26
BUF6:45 amBuffalo
13h 05m
1 stop
SNA4:50 pmSanta Ana J. Wayne/Orange Cnty
$521
Southwest
Sep 23
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
9h 00m
1 stop
BUF6:45 pmBuffalo
Sep 26
BUF6:45 amBuffalo
13h 05m
1 stop
SNA4:50 pmSanta Ana J. Wayne/Orange Cnty
$534
Southwest
May 4
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
9h 35m
1 stop
BUF7:20 pmBuffalo
May 8
BUF5:15 amBuffalo
7h 25m
1 stop
SNA9:40 amSanta Ana J. Wayne/Orange Cnty
$639

Delta flights from Santa Ana, California to Buffalo

Our best Delta deals on Santa Ana, California to Buffalo flight tickets
Delta
May 26
SNA9:10 pmSanta Ana J. Wayne/Orange Cnty
9h 34m
1 stop
BUF9:44 amBuffalo
May 29
BUF7:55 pmBuffalo
18h 20m
1 stop
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
$399
Delta
May 20
SNA11:53 amSanta Ana J. Wayne/Orange Cnty
9h 06m
1 stop
BUF11:59 pmBuffalo
May 27
BUF6:15 amBuffalo
9h 25m
1 stop
SNA12:40 pmSanta Ana J. Wayne/Orange Cnty
$402
Delta
May 26
SNA9:10 pmSanta Ana J. Wayne/Orange Cnty
9h 34m
1 stop
BUF9:44 amBuffalo
May 30
BUF5:26 pmBuffalo
8h 03m
1 stop
SNA10:29 pmSanta Ana J. Wayne/Orange Cnty
$404

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated avril 23, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

mar. 5/26

9:10 pm-9:44 am

1 stop9h 34m

Buffalo

ven. 5/29

7:55 pm-11:15 am

1 stop18h 20m

$399

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

mer. 5/20

11:53 am-11:59 pm

1 stop9h 06m

Buffalo

mer. 5/27

6:15 am-12:40 pm

1 stop9h 25m

$402

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

mar. 5/26

9:10 pm-9:44 am

1 stop9h 34m

Buffalo

sam. 5/30

5:26 pm-10:29 pm

1 stop8h 03m

$404

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

mer. 5/20

8:00 am-11:59 pm

2 stops12h 59m

Buffalo

mer. 5/27

6:15 am-12:40 pm

1 stop9h 25m

$407

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

sam. 9/19

6:50 am-9:08 pm

2 stops11h 18m

Buffalo

mar. 9/22

5:52 pm-10:14 pm

1 stop7h 22m

$409

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

mer. 5/20

8:00 am-11:59 pm

2 stops12h 59m

Buffalo

mer. 5/27

12:04 pm-9:54 pm

2 stops12h 50m

$413

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

sam. 9/19

10:29 am-11:10 pm

2 stops9h 41m

Buffalo

mar. 9/22

2:46 pm-9:37 pm

2 stops9h 51m

$418
Quickest round-trip

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

sam. 9/12

12:01 pm-11:10 pm

1 stop8h 09m

Buffalo

sam. 9/19

1:43 pm-8:01 pm

1 stop9h 18m

$443

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

sam. 9/12

6:50 am-9:08 pm

2 stops11h 18m

Buffalo

sam. 9/19

7:00 am-11:33 am

1 stop7h 33m

$448

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

sam. 9/12

10:29 am-11:10 pm

2 stops9h 41m

Buffalo

sam. 9/19

2:36 pm-9:37 pm

2 stops10h 01m

$454

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Santa Ana, California to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and Buffalo?

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Monday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $289. Flights from Santa Ana, California to Buffalo on a Sunday will generally be more expensive and average around $376. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Santa Ana, California to Buffalo when you can find flight prices for as low as $297. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Buffalo, so prices are often more expensive at around $348 per ticket.

Can stopping save me money on Santa Ana, California to Buffalo flights?

You could potentially save up to 44% on your flight if you consider stops on a Santa Ana, California to Buffalo flight.

How have Santa Ana, California to Buffalo flight prices changed over time?

As of April 2026, prices for Santa Ana, California to Buffalo flights are approximately 21% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Buffalo (SNA to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Buffalo

Fastest flight time

6h 43m

Direct flights

None
The fastest flight from Santa Ana, California to Buffalo takes 6h 43m
There are no direct flights from Santa Ana, California to Buffalo. There are no popular flight routes from Santa Ana, California to Buffalo.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Buffalo

  • How far is Santa Ana J. Wayne/Orange Cnty to Buffalo by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Buffalo will travel around 2182.8 mi. A reasonable flight in good conditions will take 6h 43m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Buffalo?

Best airlines flying from Santa Ana, California to Buffalo

Compare and see reviews for airlines that fly from Santa Ana, California to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $276Free CancellationRating
8.0
4,327 reviews
Search Southwest flights
American AirlinesPriceFrom $357Free CancellationRating
7.1
11,659 reviews
Search American Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Grand Island
Tonawanda
Orchard Park
Williamsville
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santa Ana.

Can I find flights from Santa Ana to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Buffalo?

Once all potential Santa Ana to Buffalo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
sam. 5/23
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