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Cheap flights from Santa Ana to Buffalo from $203

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Buffalo departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
11:00 am - 10:40 pmSNA-BUF
8h 40m1 stop
Southwest Logo
2:05 pm - 7:05 pmBUF-SNA
8h 00m1 stop
$417Southwest
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Tue, Nov 4 - Tue, Nov 11
Southwest Logo
11:00 am - 10:40 pmSNA-BUF
8h 40m1 stop
Southwest Logo
6:15 am - 1:25 pmBUF-SNA
10h 10m2 stops
$422Southwest
Find Deal
Tue, Nov 4 - Tue, Nov 11
Southwest Logo
7:55 pm - 8:15 amSNA-BUF
9h 20m2 stops
Southwest Logo
6:15 am - 12:35 pmBUF-SNA
9h 20m2 stops
$427Southwest
Find Deal
Tue, Nov 4 - Tue, Nov 11
American Airlines Logo
10:43 am - 10:39 pmSNA-BUF
8h 56m1 stop
American Airlines Logo
10:07 am - 2:18 pmBUF-SNA
7h 11m1 stop
$431American Airlines
Find Deal
Mon, Nov 10 - Sat, Nov 15
American Airlines Logo
11:42 am - 11:36 pmSNA-BUF
8h 54m1 stop
American Airlines Logo
6:12 am - 11:37 amBUF-SNA
8h 25m1 stop
$432American Airlines
Find Deal
Mon, Nov 10 - Sat, Nov 15
Delta Logo
9:20 pm - 12:31 pmSNA-BUF
12h 11m2 stops
Delta Logo
12:05 pm - 6:36 pmBUF-SNA
9h 31m1 stop
$437Delta
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Mon, Nov 10 - Sat, Nov 15
Delta Logo
9:20 pm - 3:05 pmSNA-BUF
14h 45m2 stops
Delta Logo
6:12 am - 2:14 pmBUF-SNA
11h 02m2 stops
$442Delta
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Mon, Nov 10 - Sat, Nov 15
United Airlines Logo
6:41 pm - 10:52 pmSNA-BUF
25h 11m1 stop
United Airlines Logo
8:10 am - 9:23 amBUF-SNA
28h 13m1 stop
$553United Airlines
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Thu, Nov 6 - Sun, Nov 9
Frontier Logo
12:01 pm - 4:29 pmSNA-BUF
25h 28m1 stop
Frontier Logo
8:19 pm - 1:35 pmBUF-SNA
44h 16m2 stops
$581Frontier
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Thu, Oct 16 - Thu, Oct 23
United Airlines Logo
9:37 am - 10:46 pmSNA-BUF
10h 09m2 stops
United Airlines Logo
7:07 am - 12:45 pmBUF-SNA
8h 38m2 stops
$609United Airlines
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Sat, Oct 18 - Wed, Oct 22

Southwest flights from Santa Ana to Buffalo

Our best Southwest deals on Santa Ana to Buffalo flight tickets
Southwest
Nov 4
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
8h 40m
1 stop
BUF10:40 pmBuffalo
Nov 11
BUF2:05 pmBuffalo
8h 00m
1 stop
SNA7:05 pmSanta Ana J. Wayne/Orange Cnty
$417
Find similar
Southwest
Nov 4
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
8h 40m
1 stop
BUF10:40 pmBuffalo
Nov 11
BUF6:15 amBuffalo
10h 10m
2 stops
SNA1:25 pmSanta Ana J. Wayne/Orange Cnty
$422
Find similar
Southwest
Nov 4
SNA7:55 pmSanta Ana J. Wayne/Orange Cnty
9h 20m
2 stops
BUF8:15 amBuffalo
Nov 11
BUF6:15 amBuffalo
9h 20m
2 stops
SNA12:35 pmSanta Ana J. Wayne/Orange Cnty
$427
Find similar

American Airlines flights from Santa Ana to Buffalo

Our best American Airlines deals on Santa Ana to Buffalo flight tickets
American Airlines
Nov 10
SNA10:43 amSanta Ana J. Wayne/Orange Cnty
8h 56m
1 stop
BUF10:39 pmBuffalo
Nov 15
BUF10:07 amBuffalo
7h 11m
1 stop
SNA2:18 pmSanta Ana J. Wayne/Orange Cnty
$431
Find similar
American Airlines
Nov 10
SNA11:42 amSanta Ana J. Wayne/Orange Cnty
8h 54m
1 stop
BUF11:36 pmBuffalo
Nov 15
BUF6:12 amBuffalo
8h 25m
1 stop
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
$432
Find similar
American Airlines
Dec 18
SNA11:09 amSanta Ana J. Wayne/Orange Cnty
8h 24m
1 stop
BUF10:33 pmBuffalo
Dec 24
BUF1:37 pmBuffalo
10h 14m
1 stop
SNA8:51 pmSanta Ana J. Wayne/Orange Cnty
$477
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 5, 2025.
Use the filters below to find and compare flights from Santa Ana to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

11:00 am-10:40 pm

1 stop8h 40m

Buffalo

Tue 11/11

2:05 pm-7:05 pm

1 stop8h 00m

$417

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

11:00 am-10:40 pm

1 stop8h 40m

Buffalo

Tue 11/11

6:15 am-1:25 pm

2 stops10h 10m

$422

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

7:55 pm-8:15 am

2 stops9h 20m

Buffalo

Tue 11/11

6:15 am-12:35 pm

2 stops9h 20m

$427

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

10:43 am-10:39 pm

1 stop8h 56m

Buffalo

Sat 11/15

10:07 am-2:18 pm

1 stop7h 11m

$431

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

11:42 am-11:36 pm

1 stop8h 54m

Buffalo

Sat 11/15

6:12 am-11:37 am

1 stop8h 25m

$432

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

9:20 pm-12:31 pm

2 stops12h 11m

Buffalo

Sat 11/15

12:05 pm-6:36 pm

1 stop9h 31m

$437

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

9:20 pm-3:05 pm

2 stops14h 45m

Buffalo

Sat 11/15

6:12 am-2:14 pm

2 stops11h 02m

$442

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 11/6

6:41 pm-10:52 pm

1 stop25h 11m

Buffalo

Sun 11/9

8:10 am-9:23 am

1 stop28h 13m

$553

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 10/16

12:01 pm-4:29 pm

1 stop25h 28m

Buffalo

Thu 10/23

8:19 pm-1:35 pm

2 stops44h 16m

$581

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 10/18

9:37 am-10:46 pm

2 stops10h 09m

Buffalo

Wed 10/22

7:07 am-12:45 pm

2 stops8h 38m

$609

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Santa Ana to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Monday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $293. Flights from Santa Ana to Buffalo on a Sunday will generally be more expensive and average around $409. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Santa Ana to Buffalo when you can find flight prices for as low as $298. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Buffalo, so prices are often more expensive at around $360 per ticket.

How have Santa Ana to Buffalo flight prices changed over time?

As of October 2025, prices for Santa Ana to Buffalo flights are approximately 100% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Buffalo (SNA to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Buffalo

Direct flights

None
There are no direct flights from Santa Ana to Buffalo. There are no popular flight routes from Santa Ana to Buffalo.
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  • How far is Santa Ana J. Wayne/Orange Cnty to Buffalo by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Buffalo will travel around 2182.8 mi. A reasonable flight in good conditions will take 6h 22m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana to Buffalo?

Best airlines flying from Santa Ana to Buffalo

Compare and see reviews for airlines that fly from Santa Ana to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $276Free CancellationRating
8.0
4,237 reviews
Search Southwest flights
American AirlinesPriceFrom $357Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $357Free CancellationRating
7.4
8,953 reviews
Search United Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Tonawanda
Amherst
Williamsville
Grand Island
Orchard Park
Lockport
West Seneca
East Aurora
Bowmansville
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santa Ana.

Can I find flights from Santa Ana to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Buffalo?

Once all potential Santa Ana to Buffalo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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