Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santa Ana, California to Buffalo from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Buffalo departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Ana, California to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
1:10 pm - 10:40 pmSNA-BUF
6h 30m1 stop
Southwest Logo
2:05 pm - 7:05 pmBUF-SNA
8h 00m1 stop
$442Southwest
Find Deal
Wed, Dec 17 - Wed, Dec 24
Southwest Logo
9:45 am - 10:00 pmSNA-BUF
9h 15m2 stops
Southwest Logo
2:05 pm - 8:35 pmBUF-SNA
9h 30m1 stop
$447Southwest
Find Deal
Wed, Dec 17 - Wed, Dec 24
Delta Logo
1:20 pm - 9:54 amSNA-BUF
17h 34m2 stops
Delta Logo
6:03 am - 10:35 amBUF-SNA
7h 32m1 stop
$460Delta
Find Deal
Thu, Jan 8 - Sun, Jan 11
Southwest Logo
10:30 am - 9:05 pmSNA-BUF
7h 35m1 stop
Southwest Logo
8:05 am - 2:30 pmBUF-SNA
9h 25m2 stops
$462Southwest
Find Deal
Thu, Dec 25 - Thu, Jan 1
Southwest Logo
7:55 pm - 7:55 amSNA-BUF
9h 00m2 stops
Southwest Logo
8:05 am - 2:30 pmBUF-SNA
9h 25m2 stops
$467Southwest
Find Deal
Thu, Dec 25 - Thu, Jan 1
Delta Logo
1:20 pm - 9:54 amSNA-BUF
17h 34m2 stops
Delta Logo
6:00 am - 11:49 amBUF-SNA
8h 49m1 stop
$470Delta
Find Deal
Thu, Jan 8 - Sun, Jan 11
Delta Logo
12:59 pm - 10:57 pmSNA-BUF
6h 58m1 stop
Delta Logo
6:03 am - 10:35 amBUF-SNA
7h 32m1 stop
$477Delta
Find Deal
Thu, Jan 8 - Sun, Jan 11
Delta Logo
1:20 pm - 9:54 amSNA-BUF
17h 34m2 stops
Delta Logo
6:03 am - 10:35 amBUF-SNA
7h 32m1 stop
$480Delta
Find Deal
Thu, Jan 8 - Sun, Jan 11
Southwest Logo
9:30 am - 8:40 pmSNA-BUF
8h 10m2 stops
Southwest Logo
12:40 pm - 8:05 pmBUF-SNA
10h 25m2 stops
$483Southwest
Find Deal
Wed, Dec 17 - Wed, Dec 24
Delta Logo
1:20 pm - 9:54 amSNA-BUF
17h 34m2 stops
Delta Logo
11:51 am - 10:15 pmBUF-SNA
13h 24m2 stops
$496Delta
Find Deal
Thu, Jan 8 - Sun, Jan 11

Delta flights from Santa Ana, California to Buffalo

Our best Delta deals on Santa Ana, California to Buffalo flight tickets
Delta
Jan 8
SNA1:20 pmSanta Ana J. Wayne/Orange Cnty
17h 34m
2 stops
BUF9:54 amBuffalo
Jan 11
BUF6:00 amBuffalo
8h 49m
1 stop
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
$470
Find similar
Delta
Jan 8
SNA12:59 pmSanta Ana J. Wayne/Orange Cnty
6h 58m
1 stop
BUF10:57 pmBuffalo
Jan 11
BUF6:03 amBuffalo
7h 32m
1 stop
SNA10:35 amSanta Ana J. Wayne/Orange Cnty
$477
Find similar
Delta
Jan 8
SNA1:20 pmSanta Ana J. Wayne/Orange Cnty
17h 34m
2 stops
BUF9:54 amBuffalo
Jan 11
BUF6:03 amBuffalo
7h 32m
1 stop
SNA10:35 amSanta Ana J. Wayne/Orange Cnty
$480
Find similar

American Airlines flights from Santa Ana, California to Buffalo

Our best American Airlines deals on Santa Ana, California to Buffalo flight tickets
American Airlines
Dec 18
SNA11:09 amSanta Ana J. Wayne/Orange Cnty
8h 24m
1 stop
BUF10:33 pmBuffalo
Dec 24
BUF6:00 amBuffalo
12h 23m
2 stops
SNA3:23 pmSanta Ana J. Wayne/Orange Cnty
$570
Find similar
American Airlines
Dec 18
SNA9:59 amSanta Ana J. Wayne/Orange Cnty
9h 34m
2 stops
BUF10:33 pmBuffalo
Dec 24
BUF6:00 amBuffalo
12h 23m
2 stops
SNA3:23 pmSanta Ana J. Wayne/Orange Cnty
$575
Find similar
American Airlines
Dec 6
SNA9:21 amSanta Ana J. Wayne/Orange Cnty
11h 46m
2 stops
BUF12:07 amBuffalo
Dec 8
BUF4:46 pmBuffalo
7h 55m
1 stop
SNA9:41 pmSanta Ana J. Wayne/Orange Cnty
$602
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

1:10 pm-10:40 pm

1 stop6h 30m

Buffalo

Wed 12/24

2:05 pm-7:05 pm

1 stop8h 00m

$442

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

9:45 am-10:00 pm

2 stops9h 15m

Buffalo

Wed 12/24

2:05 pm-8:35 pm

1 stop9h 30m

$447

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

1:20 pm-9:54 am

2 stops17h 34m

Buffalo

Sun 1/11

6:03 am-10:35 am

1 stop7h 32m

$460

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 12/25

10:30 am-9:05 pm

1 stop7h 35m

Buffalo

Thu 1/1

8:05 am-2:30 pm

2 stops9h 25m

$462

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 12/25

7:55 pm-7:55 am

2 stops9h 00m

Buffalo

Thu 1/1

8:05 am-2:30 pm

2 stops9h 25m

$467

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

1:20 pm-9:54 am

2 stops17h 34m

Buffalo

Sun 1/11

6:00 am-11:49 am

1 stop8h 49m

$470

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

12:59 pm-10:57 pm

1 stop6h 58m

Buffalo

Sun 1/11

6:03 am-10:35 am

1 stop7h 32m

$477

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

1:20 pm-9:54 am

2 stops17h 34m

Buffalo

Sun 1/11

6:03 am-10:35 am

1 stop7h 32m

$480

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

9:30 am-8:40 pm

2 stops8h 10m

Buffalo

Wed 12/24

12:40 pm-8:05 pm

2 stops10h 25m

$483

Santa AnaBuffalo

SNA - BUF

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

1:20 pm-9:54 am

2 stops17h 34m

Buffalo

Sun 1/11

11:51 am-10:15 pm

2 stops13h 24m

$496

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Buffalo from

How to get the cheapest flight ticket from Santa Ana, California to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of March, then book flights to Buffalo from Santa Ana, California during September instead. Flights to Buffalo in September, while not as cheap as those in March, still average around $360.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Monday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $298. Flights from Santa Ana, California to Buffalo on a Sunday will generally be more expensive and average around $409. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Santa Ana, California to Buffalo when you can find flight prices for as low as $297. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Buffalo, so prices are often more expensive at around $360 per ticket.

How have Santa Ana, California to Buffalo flight prices changed over time?

As of November 2025, prices for Santa Ana, California to Buffalo flights are approximately 33% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Buffalo (SNA to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Buffalo

Direct flights

None
There are no direct flights from Santa Ana, California to Buffalo. There are no popular flight routes from Santa Ana, California to Buffalo.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Buffalo by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Buffalo will travel around 2182.8 mi. A reasonable flight in good conditions will take 6h 42m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Buffalo?

Best airlines flying from Santa Ana, California to Buffalo

Compare and see reviews for airlines that fly from Santa Ana, California to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $276Free CancellationRating
8.0
4,251 reviews
Search Southwest flights
American AirlinesPriceFrom $357Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
United AirlinesPriceFrom $357Free CancellationRating
7.4
9,028 reviews
Search United Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Grand Island
Williamsville
Lockport
Orchard Park
West Seneca
East Aurora
Bowmansville
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santa Ana.

Can I find flights from Santa Ana to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Buffalo?

Once all potential Santa Ana to Buffalo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 12/21
Sun 12/28
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States