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Cheap flights from Santa Ana, California to Buffalo from $219

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:40 am - 9:37 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
6h 57m1 stop Chicago O'Hare Intl
American Airlines Logo
7:00 am - 12:29 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 29m1 stop Dallas/Fort Worth
$437American Airlines
Tue, Dec 8 - Tue, Dec 15
American Airlines Logo
10:45 am - 10:53 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
9h 08m1 stop Dallas/Fort Worth
American Airlines Logo
7:04 am - 12:35 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 31m1 stop Dallas/Fort Worth
$437American Airlines
Mon, Nov 2 - Sat, Nov 7
Delta Logo
2:00 pm - 11:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
6h 59m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 12:50 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 50m1 stop Atlanta Hartsfield-Jackson
$437Delta
Wed, Nov 11 - Sat, Nov 14
Delta Logo
9:30 pm - 10:35 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
10h 05m1 stop New York John F Kennedy Intl
Delta Logo
6:10 am - 10:26 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 16m1 stop Detroit Metropolitan Wayne County
$437Delta
Mon, Nov 16 - Wed, Nov 18
Delta Logo
12:59 pm - 12:01 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 02m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:00 am - 11:13 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 13m1 stop Atlanta Hartsfield-Jackson
$437Delta
Thu, Dec 17 - Tue, Jan 5
American Airlines Logo
9:55 am - 9:40 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 45m2 stops Phoenix Sky Harbor Intl Charlotte Douglas
American Airlines Logo
7:57 am - 2:33 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 36m1 stop Chicago O'Hare Intl
$442American Airlines
Mon, Nov 2 - Sat, Nov 7
American Airlines Logo
6:45 am - 9:37 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
11h 52m2 stops Dallas/Fort Worth Chicago O'Hare Intl
American Airlines Logo
7:03 am - 3:42 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
11h 39m2 stops Charlotte Douglas Phoenix Sky Harbor Intl
$447American Airlines
Tue, Dec 8 - Tue, Dec 15
United Airlines Logo
11:30 am - 10:54 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 24m1 stop Denver Intl
United Airlines Logo
5:45 pm - 10:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 45m1 stop Chicago O'Hare Intl
$453United Airlines
Tue, Feb 2 - Fri, Feb 5
United Airlines Logo
6:45 am - 5:02 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
8:50 am - 1:14 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 24m1 stop Denver Intl
$453United Airlines
Tue, Oct 27 - Fri, Oct 30
United Airlines Logo
11:20 am - 10:57 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 37m1 stop Denver Intl
United Airlines Logo
11:40 am - 8:19 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
11h 39m1 stop Newark
$567United Airlines
Mon, Dec 14 - Wed, Jan 6

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Delta flights from Santa Ana, California to Buffalo

Our best Delta deals on Santa Ana, California to Buffalo flight tickets
Delta
Nov 11
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 59m
1 stop
BUF11:59 pmBuffalo
Nov 18
BUF6:10 amBuffalo
7h 16m
1 stop
SNA10:26 amSanta Ana J. Wayne/Orange Cnty
$437
Delta
Nov 13
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 59m
1 stop
BUF11:59 pmBuffalo
Nov 14
BUF12:16 pmBuffalo
9h 26m
1 stop
SNA6:42 pmSanta Ana J. Wayne/Orange Cnty
$453
Delta
Oct 16
SNA9:15 pmSanta Ana J. Wayne/Orange Cnty
10h 23m
1 stop
BUF10:38 amBuffalo
Oct 20
BUF6:15 amBuffalo
7h 07m
1 stop
SNA10:22 amSanta Ana J. Wayne/Orange Cnty
$478

American Airlines flights from Santa Ana, California to Buffalo

Our best American Airlines deals on Santa Ana, California to Buffalo flight tickets
American Airlines
Nov 2
SNA9:55 amSanta Ana J. Wayne/Orange Cnty
8h 45m
2 stops
BUF9:40 pmBuffalo
Nov 7
BUF7:57 amBuffalo
9h 36m
1 stop
SNA2:33 pmSanta Ana J. Wayne/Orange Cnty
$442
American Airlines
Oct 16
SNA10:42 amSanta Ana J. Wayne/Orange Cnty
9h 12m
1 stop
BUF10:54 pmBuffalo
Oct 19
BUF6:03 pmBuffalo
7h 26m
1 stop
SNA10:29 pmSanta Ana J. Wayne/Orange Cnty
$487
American Airlines
Oct 16
SNA7:31 pmSanta Ana J. Wayne/Orange Cnty
12h 14m
2 stops
BUF10:45 amBuffalo
Oct 19
BUF6:03 pmBuffalo
7h 26m
1 stop
SNA10:29 pmSanta Ana J. Wayne/Orange Cnty
$492

momondo Fare Finder

 
Use the filters below to find and compare flights from Santa Ana, California to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 12/8

11:40 am-9:37 pm

1 stop6h 57m

Buffalo

Tue 12/15

7:00 am-12:29 pm

1 stop8h 29m

$437

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

10:45 am-10:53 pm

1 stop9h 08m

Buffalo

Sat 11/7

7:04 am-12:35 pm

1 stop8h 31m

$437

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 11/11

2:00 pm-11:59 pm

1 stop6h 59m

Buffalo

Sat 11/14

6:00 am-12:50 pm

1 stop9h 50m

$437

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/16

9:30 pm-10:35 am

1 stop10h 05m

Buffalo

Wed 11/18

6:10 am-10:26 am

1 stop7h 16m

$437

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 12/17

12:59 pm-12:01 am

1 stop8h 02m

Buffalo

Tue 1/5

6:00 am-11:13 am

1 stop8h 13m

$437

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

9:55 am-9:40 pm

2 stops8h 45m

Buffalo

Sat 11/7

7:57 am-2:33 pm

1 stop9h 36m

$442

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 12/8

6:45 am-9:37 pm

2 stops11h 52m

Buffalo

Tue 12/15

7:03 am-3:42 pm

2 stops11h 39m

$447

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 2/2

11:30 am-10:54 pm

1 stop8h 24m

Buffalo

Fri 2/5

5:45 pm-10:30 pm

1 stop7h 45m

$453
Quickest round-trip

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

6:45 am-5:02 pm

1 stop7h 17m

Buffalo

Fri 10/30

8:50 am-1:14 pm

1 stop7h 24m

$453

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 12/14

11:20 am-10:57 pm

1 stop8h 37m

Buffalo

Wed 1/6

11:40 am-8:19 pm

1 stop11h 39m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Santa Ana, California to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and Buffalo?

Prices are currently low for flights on this route.

Typical prices usually range from $572 to $654.
The lowest price recently found on this route was $437.

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of February, then book flights to Buffalo from Santa Ana, California during January instead. Flights to Buffalo in January, while not as cheap as those in February, still average around $456.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Monday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $378. Flights from Santa Ana, California to Buffalo on a Thursday will generally be more expensive and average around $491. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Santa Ana, California to Buffalo when you can find flight prices for as low as $284. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Buffalo, so prices are often more expensive at around $435 per ticket.

How have Santa Ana, California to Buffalo flight prices changed over time?

As of September 2026, prices for Santa Ana, California to Buffalo flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Buffalo (SNA to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Buffalo

Best Price Found

$219

Fastest flight time

6h 38m

Direct flights

None
The best one-way flight to Buffalo from Santa Ana, California in the past 72 hours is $219. The best round-trip flight deal from Santa Ana, California to Buffalo found on momondo in the last 72 hours is $437.
The fastest flight from Santa Ana, California to Buffalo takes 6h 38m
There are no direct flights from Santa Ana, California to Buffalo. There are no popular flight routes from Santa Ana, California to Buffalo.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Buffalo

  • How far is Santa Ana J. Wayne/Orange Cnty to Buffalo by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Buffalo will travel around 2182.8 mi. A reasonable flight in good conditions will take 6h 38m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Buffalo?

Best airlines flying from Santa Ana, California to Buffalo

Compare and see reviews for airlines that fly from Santa Ana, California to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $350Free CancellationRating
7.4
10,226 reviews
Search United Airlines flights
American AirlinesPriceFrom $370Free CancellationRating
7.0
12,076 reviews
Search American Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Williamsville
Tonawanda
Bowmansville
Lockport
Orchard Park
West Seneca
Grand Island
East Aurora
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santa Ana.

Can I find flights from Santa Ana to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Buffalo?

Once all potential Santa Ana to Buffalo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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