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Cheap flights from Santa Ana, California to Buffalo from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Buffalo departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:01 pm - 11:01 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 00m1 stop Dallas/Fort Worth
American Airlines Logo
12:56 pm - 7:59 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 03m1 stop Charlotte Douglas
$385American Airlines
Wed, Sep 2 - Wed, Sep 9
American Airlines Logo
12:01 pm - 11:01 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 00m1 stop Dallas/Fort Worth
American Airlines Logo
5:29 am - 12:45 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 16m2 stops Washington, D.C. Reagan-National Dallas/Fort Worth
$390American Airlines
Wed, Sep 2 - Wed, Sep 9
American Airlines Logo
7:31 pm - 10:53 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
12h 22m2 stops Phoenix Sky Harbor Intl Chicago O'Hare Intl
American Airlines Logo
7:00 am - 1:45 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 45m1 stop Dallas/Fort Worth
$390American Airlines
Mon, Oct 5 - Wed, Oct 28
American Airlines Logo
9:07 am - 11:36 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
11h 29m2 stops Dallas/Fort Worth Washington, D.C. Reagan-National
American Airlines Logo
10:43 am - 6:21 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 38m2 stops Philadelphia Phoenix Sky Harbor Intl
$395American Airlines
Wed, Sep 2 - Wed, Sep 9
Delta Logo
8:11 am - 6:23 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 12m1 stop Minneapolis St Paul
Delta Logo
6:20 am - 10:26 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 06m1 stop Detroit Metropolitan Wayne County
$407Delta
Sat, Sep 5 - Wed, Sep 9
Delta Logo
12:20 pm - 11:09 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 49m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:20 am - 10:26 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 06m1 stop Detroit Metropolitan Wayne County
$407Delta
Wed, Sep 2 - Wed, Sep 9
United Airlines Logo
1:08 pm - 10:37 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
6h 29m1 stop Denver Intl
United Airlines Logo
5:58 pm - 10:25 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 27m1 stop Chicago O'Hare Intl
$407United Airlines
Wed, Sep 9 - Wed, Sep 16
Southwest Logo
7:30 am - 9:10 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
10h 40m2 stops Dallas Love Field Baltimore/Washington
Southwest Logo
3:55 pm - 8:55 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 00m1 stop Denver Intl
$412Southwest
Wed, Sep 9 - Wed, Sep 16
Southwest Logo
10:00 am - 9:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 55m2 stops Phoenix Sky Harbor Intl Baltimore/Washington
Southwest Logo
4:00 pm - 9:50 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 50m2 stops Chicago Midway Denver Intl
$439Southwest
Tue, Nov 17 - Mon, Nov 23
Southwest Logo
1:40 pm - 12:15 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 35m1 stop Las Vegas Harry Reid Intl
Southwest Logo
3:25 pm - 9:25 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 00m1 stop Las Vegas Harry Reid Intl
$469Southwest
Thu, Oct 8 - Tue, Oct 20

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Delta flights from Santa Ana, California to Buffalo

Our best Delta deals on Santa Ana, California to Buffalo flight tickets
Delta
Sep 2
SNA12:20 pmSanta Ana J. Wayne/Orange Cnty
7h 49m
1 stop
BUF11:09 pmBuffalo
Sep 9
BUF6:20 amBuffalo
7h 06m
1 stop
SNA10:26 amSanta Ana J. Wayne/Orange Cnty
$407
Delta
Sep 1
SNA12:20 pmSanta Ana J. Wayne/Orange Cnty
7h 49m
1 stop
BUF11:09 pmBuffalo
Sep 8
BUF6:05 amBuffalo
9h 28m
1 stop
SNA12:33 pmSanta Ana J. Wayne/Orange Cnty
$469
Delta
Aug 18
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
9h 10m
1 stop
BUF6:55 pmBuffalo
Aug 22
BUF5:13 pmBuffalo
8h 12m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
$649

United Airlines flights from Santa Ana, California to Buffalo

Our best United Airlines deals on Santa Ana, California to Buffalo flight tickets
United Airlines
Sep 3
SNA10:20 amSanta Ana J. Wayne/Orange Cnty
7h 47m
1 stop
BUF9:07 pmBuffalo
Sep 10
BUF5:58 pmBuffalo
7h 27m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
$491
United Airlines
Sep 3
SNA10:20 amSanta Ana J. Wayne/Orange Cnty
7h 47m
1 stop
BUF9:07 pmBuffalo
Sep 10
BUF6:30 amBuffalo
10h 27m
2 stops
SNA1:57 pmSanta Ana J. Wayne/Orange Cnty
$497
United Airlines
Sep 5
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
11h 49m
2 stops
BUF11:44 pmBuffalo
Sep 9
BUF10:30 amBuffalo
11h 17m
2 stops
SNA6:47 pmSanta Ana J. Wayne/Orange Cnty
$500

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 9/2

12:01 pm-11:01 pm

1 stop8h 00m

Buffalo

Wed 9/9

12:56 pm-7:59 pm

1 stop10h 03m

$385

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 9/2

12:01 pm-11:01 pm

1 stop8h 00m

Buffalo

Wed 9/9

5:29 am-12:45 pm

2 stops10h 16m

$390

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Mon 10/5

7:31 pm-10:53 am

2 stops12h 22m

Buffalo

Wed 10/28

7:00 am-1:45 pm

1 stop9h 45m

$390

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 9/2

9:07 am-11:36 pm

2 stops11h 29m

Buffalo

Wed 9/9

10:43 am-6:21 pm

2 stops10h 38m

$395

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 9/5

8:11 am-6:23 pm

1 stop7h 12m

Buffalo

Wed 9/9

6:20 am-10:26 am

1 stop7h 06m

$407

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 9/2

12:20 pm-11:09 pm

1 stop7h 49m

Buffalo

Wed 9/9

6:20 am-10:26 am

1 stop7h 06m

$407
Quickest round-trip

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

1:08 pm-10:37 pm

1 stop6h 29m

Buffalo

Wed 9/16

5:58 pm-10:25 pm

1 stop7h 27m

$407

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

7:30 am-9:10 pm

2 stops10h 40m

Buffalo

Wed 9/16

3:55 pm-8:55 pm

1 stop8h 00m

$412

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 11/17

10:00 am-9:55 pm

2 stops8h 55m

Buffalo

Mon 11/23

4:00 pm-9:50 pm

2 stops8h 50m

$439

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 10/8

1:40 pm-12:15 am

1 stop7h 35m

Buffalo

Tue 10/20

3:25 pm-9:25 pm

1 stop9h 00m

$469

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Santa Ana, California to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and Buffalo?

Prices are currently low for flights on this route.

Typical prices usually range from $389 to $545.
The lowest price recently found on this route was $385.

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of February, then book flights to Buffalo from Santa Ana, California during August instead. Flights to Buffalo in August, while not as cheap as those in February, still average around $418.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Monday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $380. Flights from Santa Ana, California to Buffalo on a Friday will generally be more expensive and average around $468. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Santa Ana, California to Buffalo when you can find flight prices for as low as $284. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Buffalo, so prices are often more expensive at around $431 per ticket.

Can stopping save me money on Santa Ana, California to Buffalo flights?

You could potentially save up to 25% on your flight if you consider stops on a Santa Ana, California to Buffalo flight.

How have Santa Ana, California to Buffalo flight prices changed over time?

As of August 2026, prices for Santa Ana, California to Buffalo flights are approximately 9% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Buffalo (SNA to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Buffalo

Fastest flight time

6h 49m

Direct flights

None
The fastest flight from Santa Ana, California to Buffalo takes 6h 49m
There are no direct flights from Santa Ana, California to Buffalo. There are no popular flight routes from Santa Ana, California to Buffalo.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Buffalo

  • How far is Santa Ana J. Wayne/Orange Cnty to Buffalo by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Buffalo will travel around 2182.8 mi. A reasonable flight in good conditions will take 6h 49m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Buffalo?

Best airlines flying from Santa Ana, California to Buffalo

Compare and see reviews for airlines that fly from Santa Ana, California to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $276Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
American AirlinesPriceFrom $362Free CancellationRating
7.1
11,866 reviews
Search American Airlines flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Williamsville
Orchard Park
Grand Island
Bowmansville
West Seneca
Lockport
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santa Ana.

Can I find flights from Santa Ana to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Buffalo?

Once all potential Santa Ana to Buffalo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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