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Cheap flights from Santa Ana, California to Buffalo from $208

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:54 am - 9:49 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
9h 55m1 stop Chicago O'Hare Intl
American Airlines Logo
7:00 am - 12:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 30m1 stop Dallas/Fort Worth
$447American Airlines
Sat, Dec 12 - Wed, Dec 16
United Airlines Logo
10:20 am - 8:56 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 36m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 11:37 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 07m1 stop Chicago O'Hare Intl
$447United Airlines
Sat, Dec 12 - Wed, Dec 16
Delta Logo
12:59 pm - 12:01 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 02m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:10 am - 10:30 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 20m1 stop Detroit Metropolitan Wayne County
$447Delta
Tue, Dec 15 - Fri, Dec 18
Delta Logo
11:46 am - 11:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
9h 13m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:05 am - 11:20 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 15m1 stop Atlanta Hartsfield-Jackson
$447Delta
Thu, Jan 7 - Sat, Jan 9
United Airlines Logo
1:00 pm - 10:53 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
6h 53m1 stop Denver Intl
United Airlines Logo
5:43 pm - 10:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 47m1 stop Chicago O'Hare Intl
$447United Airlines
Wed, Jan 6 - Mon, Jan 11
American Airlines Logo
8:48 am - 10:56 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
11h 08m2 stops Chicago O'Hare Intl New York LaGuardia
American Airlines Logo
6:00 am - 10:42 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 42m1 stop Chicago O'Hare Intl
$452American Airlines
Wed, Jan 6 - Mon, Jan 11
United Airlines Logo
6:45 am - 4:57 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 12m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 2:18 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 48m2 stops Chicago O'Hare Intl San Francisco
$452United Airlines
Sat, Dec 12 - Wed, Dec 16
Southwest Logo
11:10 am - 10:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 15m2 stops Phoenix Sky Harbor Intl Denver Intl
Southwest Logo
2:00 pm - 8:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 30m2 stops Chicago Midway Las Vegas Harry Reid Intl
$457Southwest
Sat, Dec 12 - Wed, Dec 16
Southwest Logo
7:30 pm - 8:25 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
9h 55m2 stops Las Vegas Harry Reid Intl Baltimore/Washington
Southwest Logo
2:05 pm - 8:50 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 45m2 stops Chicago Midway Las Vegas Harry Reid Intl
$457Southwest
Wed, Jan 6 - Mon, Jan 11
American Airlines Logo
9:51 am - 12:14 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
11h 23m2 stops Phoenix Sky Harbor Intl Charlotte Douglas
American Airlines Logo
7:03 am - 2:04 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 01m1 stop Dallas/Fort Worth
$572American Airlines
Sat, Dec 26 - Thu, Dec 31

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United Airlines flights from Santa Ana, California to Buffalo

Our best United Airlines deals on Santa Ana, California to Buffalo flight tickets
United Airlines
Dec 3
SNA1:00 pmSanta Ana J. Wayne/Orange Cnty
6h 57m
1 stop
BUF10:57 pmBuffalo
Dec 7
BUF8:17 amBuffalo
7h 44m
1 stop
SNA1:01 pmSanta Ana J. Wayne/Orange Cnty
$577
United Airlines
Dec 10
SNA1:00 pmSanta Ana J. Wayne/Orange Cnty
6h 57m
1 stop
BUF10:57 pmBuffalo
Dec 15
BUF10:00 amBuffalo
13h 46m
2 stops
SNA8:46 pmSanta Ana J. Wayne/Orange Cnty
$582
United Airlines
Dec 3
SNA7:15 amSanta Ana J. Wayne/Orange Cnty
12h 42m
2 stops
BUF10:57 pmBuffalo
Dec 7
BUF3:00 pmBuffalo
10h 15m
2 stops
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
$587

Delta flights from Santa Ana, California to Buffalo

Our best Delta deals on Santa Ana, California to Buffalo flight tickets
Delta
Jan 6
SNA11:46 amSanta Ana J. Wayne/Orange Cnty
9h 13m
1 stop
BUF11:59 pmBuffalo
Jan 9
BUF6:05 amBuffalo
8h 15m
1 stop
SNA11:20 amSanta Ana J. Wayne/Orange Cnty
$447
Delta
Jan 6
SNA9:50 amSanta Ana J. Wayne/Orange Cnty
10h 23m
2 stops
BUF11:13 pmBuffalo
Jan 13
BUF6:15 amBuffalo
7h 19m
1 stop
SNA10:34 amSanta Ana J. Wayne/Orange Cnty
$452
Delta
Jan 5
SNA7:05 pmSanta Ana J. Wayne/Orange Cnty
12h 34m
2 stops
BUF10:39 amBuffalo
Jan 13
BUF1:00 pmBuffalo
12h 03m
2 stops
SNA10:03 pmSanta Ana J. Wayne/Orange Cnty
$458

momondo Fare Finder

 
Use the filters below to find and compare flights from Santa Ana, California to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 12/12

8:54 am-9:49 pm

1 stop9h 55m

Buffalo

Wed 12/16

7:00 am-12:30 pm

1 stop8h 30m

$447

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 12/12

10:20 am-8:56 pm

1 stop7h 36m

Buffalo

Wed 12/16

6:30 am-11:37 am

1 stop8h 07m

$447

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Tue 12/15

12:59 pm-12:01 am

1 stop8h 02m

Buffalo

Fri 12/18

6:10 am-10:30 am

1 stop7h 20m

$447

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Thu 1/7

11:46 am-11:59 pm

1 stop9h 13m

Buffalo

Sat 1/9

6:05 am-11:20 am

1 stop8h 15m

$447
Quickest round-trip

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 1/6

1:00 pm-10:53 pm

1 stop6h 53m

Buffalo

Mon 1/11

5:43 pm-10:30 pm

1 stop7h 47m

$447

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 1/6

8:48 am-10:56 pm

2 stops11h 08m

Buffalo

Mon 1/11

6:00 am-10:42 am

1 stop7h 42m

$452

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 12/12

6:45 am-4:57 pm

1 stop7h 12m

Buffalo

Wed 12/16

6:30 am-2:18 pm

2 stops10h 48m

$452

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 12/12

11:10 am-10:25 pm

2 stops8h 15m

Buffalo

Wed 12/16

2:00 pm-8:30 pm

2 stops9h 30m

$457

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Wed 1/6

7:30 pm-8:25 am

2 stops9h 55m

Buffalo

Mon 1/11

2:05 pm-8:50 pm

2 stops9h 45m

$457

Santa AnaBuffalo

SNA Santa Ana J. Wayne/Orange Cnty - BUF Buffalo

SNABUF

Santa Ana J. Wayne/Orange Cnty

Sat 12/26

9:51 am-12:14 am

2 stops11h 23m

Buffalo

Thu 12/31

7:03 am-2:04 pm

1 stop10h 01m

$572

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Santa Ana, California to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of February, then book flights to Buffalo from Santa Ana, California during January instead. Flights to Buffalo in January, while not as cheap as those in February, still average around $456.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Monday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $371. Flights from Santa Ana, California to Buffalo on a Thursday will generally be more expensive and average around $490. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

At noon is the cheapest time of day to fly from Santa Ana, California to Buffalo when you can find flight prices for as low as $284. Flying to Buffalo at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Buffalo, so prices are often more expensive at around $438 per ticket.

Can stopping save me money on Santa Ana, California to Buffalo flights?

You could potentially save up to 11% on your flight if you consider stops on a Santa Ana, California to Buffalo flight.

How have Santa Ana, California to Buffalo flight prices changed over time?

As of November 2026, prices for Santa Ana, California to Buffalo flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Buffalo (SNA to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Buffalo

Best Price Found

$208

Fastest flight time

6h 57m

Direct flights

None
The best one-way flight to Buffalo from Santa Ana, California in the past 72 hours is $208. The best round-trip flight deal from Santa Ana, California to Buffalo found on momondo in the last 72 hours is $447.
The fastest flight from Santa Ana, California to Buffalo takes 6h 57m
There are no direct flights from Santa Ana, California to Buffalo. There are no popular flight routes from Santa Ana, California to Buffalo.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Buffalo

  • How far is Santa Ana J. Wayne/Orange Cnty to Buffalo by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Buffalo will travel around 2182.8 mi. A reasonable flight in good conditions will take 6h 57m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Buffalo?

Best airlines flying from Santa Ana, California to Buffalo

Compare and see reviews for airlines that fly from Santa Ana, California to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $350Free CancellationRating
7.3
10,460 reviews
Search United Airlines flights
American AirlinesPriceFrom $370Free CancellationRating
7.0
12,230 reviews
Search American Airlines flights
SouthwestPriceFrom $462Free CancellationRating
8.0
4,215 reviews
Search Southwest flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Williamsville
Amherst
Tonawanda
Bowmansville
Lockport
Orchard Park
West Seneca
Grand Island
East Aurora
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santa Ana.

Can I find flights from Santa Ana to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Buffalo?

Once all potential Santa Ana to Buffalo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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