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Cheap flights from Rome to San Diego from $381

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rome to San Diego departing on 4/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:05 pm - 12:48 pm
FCO
-
SAN
26h 43m
1 stop
Multiple Airlines Logo
5:15 pm - 9:00 am
SAN
-
FCO
30h 45m
2 stops
$757Multiple Airlines
Fri, May 1 - Sun, May 10
Multiple Airlines Logo
7:05 pm - 12:48 pm
FCO
-
SAN
26h 43m
1 stop
Multiple Airlines Logo
10:00 pm - 11:55 am
SAN
-
FCO
28h 55m
2 stops
$765Multiple Airlines
Fri, May 1 - Sat, May 9
Multiple Airlines Logo
7:05 pm - 12:48 pm
FCO
-
SAN
26h 43m
1 stop
Multiple Airlines Logo
9:19 am - 11:40 pm
SAN
-
FCO
29h 21m
2 stops
$772Multiple Airlines
Fri, May 1 - Thu, May 7
Multiple Airlines Logo
8:25 pm - 1:05 pm
FCO
-
SAN
24h 40m
1 stop
Multiple Airlines Logo
7:00 am - 6:05 am
SAN
-
FCO
15h 05m
1 stop
$784Multiple Airlines
Mon, Mar 16 - Sun, Mar 22
Delta Logo
6:10 am - 1:05 pm
FCO
-
SAN
14h 55m
1 stop
Delta Logo
6:15 am - 10:50 am
SAN
-
FCO
19h 35m
2 stops
$785Delta
Tue, Mar 24 - Tue, Mar 31
KLM Logo
8:25 pm - 1:05 pm
FCO
-
SAN
24h 40m
1 stop
KLM Logo
6:15 am - 11:00 am
SAN
-
FCO
19h 45m
1 stop
$789KLM
Mon, Mar 23 - Mon, Mar 30
Delta Logo
6:30 am - 11:50 am
FCO
-
SAN
14h 20m
1 stop
Delta Logo
3:15 pm - 5:30 pm
SAN
-
FCO
17h 15m
2 stops
$792Delta
Thu, Apr 30 - Sat, May 9
KLM Logo
6:30 am - 11:50 am
FCO
-
SAN
14h 20m
1 stop
KLM Logo
7:20 am - 10:05 am
SAN
-
FCO
17h 45m
1 stop
$795KLM
Thu, Apr 30 - Mon, May 11
Air France Logo
8:45 pm - 6:50 pm
FCO
-
SAN
30h 05m
2 stops
Air France Logo
7:00 am - 6:05 am
SAN
-
FCO
15h 05m
1 stop
$796Air France
Mon, Mar 16 - Sun, Mar 22
KLM Logo
6:30 am - 11:50 am
FCO
-
SAN
14h 20m
1 stop
KLM Logo
1:40 pm - 4:25 pm
SAN
-
FCO
17h 45m
1 stop
$797KLM
Thu, Apr 30 - Sat, May 9

Delta flights from Rome to San Diego

Our best Delta deals on Rome to San Diego flight tickets
Delta
Mar 24
FCO6:10 amRome Fiumicino
14h 55m
1 stop
SAN1:05 pmSan Diego
Mar 31
SAN6:15 amSan Diego
19h 35m
2 stops
FCO10:50 amRome Fiumicino
$785
Delta
Apr 30
FCO6:30 amRome Fiumicino
14h 20m
1 stop
SAN11:50 amSan Diego
May 9
SAN3:15 pmSan Diego
17h 15m
2 stops
FCO5:30 pmRome Fiumicino
$792
Delta
Mar 16
FCO10:05 amRome Fiumicino
22h 06m
2 stops
SAN12:11 amSan Diego
Mar 22
SAN7:00 amSan Diego
15h 05m
1 stop
FCO6:05 amRome Fiumicino
$802

United Airlines flights from Rome to San Diego

Our best United Airlines deals on Rome to San Diego flight tickets
United Airlines
Apr 28
FCO6:50 amRome Fiumicino
22h 22m
2 stops
SAN8:12 pmSan Diego
May 10
SAN8:54 amSan Diego
18h 26m
1 stop
FCO12:20 pmRome Fiumicino
$916
United Airlines
Apr 1
FCO6:50 amRome Fiumicino
19h 22m
2 stops
SAN5:12 pmSan Diego
Apr 5
SAN12:40 pmSan Diego
14h 40m
1 stop
FCO12:20 pmRome Fiumicino
$918
United Airlines
Apr 28
FCO6:50 amRome Fiumicino
22h 22m
2 stops
SAN8:12 pmSan Diego
May 8
SAN5:15 pmSan Diego
19h 45m
1 stop
FCO10:00 pmRome Fiumicino
$920

momondo Fare Finder

 
Customize your flight search to find flights from Rome to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Rome to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Fri 5/1

7:05 pm-12:48 pm

1 stop26h 43m

San Diego

Sun 5/10

5:15 pm-9:00 am

2 stops30h 45m

$757

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Fri 5/1

7:05 pm-12:48 pm

1 stop26h 43m

San Diego

Sat 5/9

10:00 pm-11:55 am

2 stops28h 55m

$765

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Fri 5/1

7:05 pm-12:48 pm

1 stop26h 43m

San Diego

Thu 5/7

9:19 am-11:40 pm

2 stops29h 21m

$772

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Mon 3/16

8:25 pm-1:05 pm

1 stop24h 40m

San Diego

Sun 3/22

7:00 am-6:05 am

1 stop15h 05m

$784

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Tue 3/24

6:10 am-1:05 pm

1 stop14h 55m

San Diego

Tue 3/31

6:15 am-10:50 am

2 stops19h 35m

$785

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Mon 3/23

8:25 pm-1:05 pm

1 stop24h 40m

San Diego

Mon 3/30

6:15 am-11:00 am

1 stop19h 45m

$789

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Thu 4/30

6:30 am-11:50 am

1 stop14h 20m

San Diego

Sat 5/9

3:15 pm-5:30 pm

2 stops17h 15m

$792

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Thu 4/30

6:30 am-11:50 am

1 stop14h 20m

San Diego

Mon 5/11

7:20 am-10:05 am

1 stop17h 45m

$795

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Mon 3/16

8:45 pm-6:50 pm

2 stops30h 05m

San Diego

Sun 3/22

7:00 am-6:05 am

1 stop15h 05m

$796

RomeSan Diego

FCO - SAN

FCOSAN

Rome Fiumicino

Thu 4/30

6:30 am-11:50 am

1 stop14h 20m

San Diego

Sat 5/9

1:40 pm-4:25 pm

1 stop17h 45m

$797

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Rome to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Rome and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Rome during the month March is also very affordable. Most momondo users find prices during this month for around $788.

Can stopping save me money on Rome to San Diego flights?

You could potentially save up to 22% on your flight if you consider stops on a Rome to San Diego flight.

How have Rome to San Diego flight prices changed over time?

As of February 2026, prices for Rome to San Diego flights are approximately 7% cheaper when compared to flights at the same time last year.

When to book flights from Rome to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Rome to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rome to San Diego (ROM to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rome to San Diego

Fastest flight time

14h 20m

Direct flights

None
The fastest flight from Rome to San Diego takes 14h 20m
There are no direct flights from Rome to San Diego. There are no popular flight routes from Rome to San Diego.
Search flight deals

  • How far is Rome to San Diego by plane?

    The straight-line distance from Rome to San Diego is 6366.7 mi. A reasonable flight in good conditions will take 14h 20m.

  • When did momondo last update prices for flights from Rome to San Diego Airport?

    Prices for flights from Rome to San Diego Airport were last updated today.

  • How old do you have to be to fly from Rome to San Diego Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Rome to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents required for your trip to San Diego Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Diego Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Rome to San Diego?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Rome to San Diego. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Rome to San Diego with flexible booking policies on momondo?

Flights from Rome to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Rome to San Diego?

Once you have performed a search for Rome to San Diego flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Rome to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Rome to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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