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Cheap flights from Roanoke to Los Angeles from $351

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Los Angeles departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 2:03 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
10h 03m1 stop Dallas/Fort Worth
American Airlines Logo
10:40 am - 10:51 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
9h 11m1 stop Dallas/Fort Worth
$367American Airlines
Tue, Dec 15 - Sat, Jan 9
American Airlines Logo
6:52 am - 1:45 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
9h 53m1 stop Dallas/Fort Worth
American Airlines Logo
10:42 am - 10:47 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
9h 05m1 stop Dallas/Fort Worth
$367American Airlines
Sat, Oct 17 - Tue, Oct 20
American Airlines Logo
4:54 pm - 9:27 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
7h 33m1 stop Chicago O'Hare Intl
American Airlines Logo
7:15 am - 6:53 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
8h 38m1 stop Charlotte Douglas
$367American Airlines
Wed, Nov 4 - Wed, Dec 2
United Airlines Logo
6:49 am - 2:03 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
10h 14m2 stops Chicago O'Hare Intl San Francisco
United Airlines Logo
10:37 am - 10:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
9h 22m1 stop Chicago O'Hare Intl
$372United Airlines
Sat, Oct 17 - Tue, Oct 20
United Airlines Logo
6:49 am - 3:13 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
11h 24m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
10:37 am - 10:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
9h 22m1 stop Chicago O'Hare Intl
$372United Airlines
Sat, Oct 17 - Sat, Oct 24
American Airlines Logo
6:00 am - 2:03 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
11h 03m2 stops Philadelphia Dallas/Fort Worth
American Airlines Logo
10:40 am - 10:51 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
9h 11m1 stop Dallas/Fort Worth
$372American Airlines
Tue, Dec 15 - Sat, Jan 9
Delta Logo
6:00 am - 12:44 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
9h 44m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:38 am - 9:57 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
7h 19m1 stop Atlanta Hartsfield-Jackson
$373Delta
Wed, Oct 28 - Sun, Nov 1
United Airlines Logo
5:51 pm - 10:26 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
7h 35m1 stop Chicago O'Hare Intl
United Airlines Logo
10:37 am - 10:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
9h 22m1 stop Chicago O'Hare Intl
$373United Airlines
Fri, Oct 16 - Tue, Oct 20
Delta Logo
4:46 pm - 10:04 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
8h 18m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 11:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
6h 59m1 stop Atlanta Hartsfield-Jackson
$443Delta
Fri, Sep 11 - Tue, Sep 15
Delta Logo
6:00 am - 12:33 pmROA  Roanoke-SNA Santa Ana J. Wayne/Orange Cnty
9h 33m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 11:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-ROA Roanoke
6h 59m1 stop Atlanta Hartsfield-Jackson
$507Delta
Thu, Sep 10 - Tue, Sep 15

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Delta flights from Roanoke to Santa Ana, California

Our best Delta deals on Roanoke to Santa Ana, California flight tickets
Delta
Oct 28
ROA6:00 amRoanoke
9h 44m
1 stop
SNA12:44 pmSanta Ana J. Wayne/Orange Cnty
Nov 1
SNA11:38 amSanta Ana J. Wayne/Orange Cnty
7h 19m
1 stop
ROA9:57 pmRoanoke
$373
Delta
Sep 11
ROA4:46 pmRoanoke
8h 18m
1 stop
SNA10:04 pmSanta Ana J. Wayne/Orange Cnty
Sep 15
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 59m
1 stop
ROA11:59 pmRoanoke
$443
Delta
Sep 11
ROA4:46 pmRoanoke
8h 18m
1 stop
SNA10:04 pmSanta Ana J. Wayne/Orange Cnty
Sep 15
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
6h 59m
1 stop
ROA11:59 pmRoanoke
$507

American Airlines flights from Roanoke to Santa Ana, California

Our best American Airlines deals on Roanoke to Santa Ana, California flight tickets
American Airlines
Dec 15
ROA7:00 amRoanoke
10h 03m
1 stop
SNA2:03 pmSanta Ana J. Wayne/Orange Cnty
Jan 9
SNA10:40 amSanta Ana J. Wayne/Orange Cnty
9h 11m
1 stop
ROA10:51 pmRoanoke
$367
American Airlines
Dec 15
ROA9:14 amRoanoke
11h 28m
2 stops
SNA5:42 pmSanta Ana J. Wayne/Orange Cnty
Jan 9
SNA7:35 pmSanta Ana J. Wayne/Orange Cnty
11h 01m
2 stops
ROA9:36 amRoanoke
$377
American Airlines
Oct 28
ROA6:52 amRoanoke
8h 44m
1 stop
SNA12:36 pmSanta Ana J. Wayne/Orange Cnty
Nov 1
SNA7:39 pmSanta Ana J. Wayne/Orange Cnty
11h 04m
2 stops
ROA9:43 amRoanoke
$378

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Roanoke to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Tue 12/15

7:00 am-2:03 pm

1 stop10h 03m

Santa Ana J. Wayne/Orange Cnty

Sat 1/9

10:40 am-10:51 pm

1 stop9h 11m

$367

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Sat 10/17

6:52 am-1:45 pm

1 stop9h 53m

Santa Ana J. Wayne/Orange Cnty

Tue 10/20

10:42 am-10:47 pm

1 stop9h 05m

$367

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Wed 11/4

4:54 pm-9:27 pm

1 stop7h 33m

Santa Ana J. Wayne/Orange Cnty

Wed 12/2

7:15 am-6:53 pm

1 stop8h 38m

$367

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Sat 10/17

6:49 am-2:03 pm

2 stops10h 14m

Santa Ana J. Wayne/Orange Cnty

Tue 10/20

10:37 am-10:59 pm

1 stop9h 22m

$372

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Sat 10/17

6:49 am-3:13 pm

2 stops11h 24m

Santa Ana J. Wayne/Orange Cnty

Sat 10/24

10:37 am-10:59 pm

1 stop9h 22m

$372

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Tue 12/15

6:00 am-2:03 pm

2 stops11h 03m

Santa Ana J. Wayne/Orange Cnty

Sat 1/9

10:40 am-10:51 pm

1 stop9h 11m

$372

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Wed 10/28

6:00 am-12:44 pm

1 stop9h 44m

Santa Ana J. Wayne/Orange Cnty

Sun 11/1

11:38 am-9:57 pm

1 stop7h 19m

$373

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Fri 10/16

5:51 pm-10:26 pm

1 stop7h 35m

Santa Ana J. Wayne/Orange Cnty

Tue 10/20

10:37 am-10:59 pm

1 stop9h 22m

$373
Quickest round-trip

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Fri 9/11

4:46 pm-10:04 pm

1 stop8h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 9/15

2:00 pm-11:59 pm

1 stop6h 59m

$443

RoanokeSanta Ana

ROA Roanoke - SNA Santa Ana J. Wayne/Orange Cnty

ROASNA

Roanoke

Thu 9/10

6:00 am-12:33 pm

1 stop9h 33m

Santa Ana J. Wayne/Orange Cnty

Tue 9/15

2:00 pm-11:59 pm

1 stop6h 59m

$507

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, May is the cheapest month to fly from Roanoke to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of May, then book flights to Santa Ana, California from Roanoke during April instead. Flights to Santa Ana, California in April, while not as cheap as those in May, still average around $0.

When to book flights from Roanoke to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Santa Ana, California (ROA to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Santa Ana, California

Fastest flight time

7h 34m

Direct flights

None
The fastest flight from Roanoke to Santa Ana, California takes 7h 34m
There are no direct flights from Roanoke to Santa Ana, California. There are no popular flight routes from Roanoke to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Roanoke to Santa Ana, California

  • How far is Roanoke to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2131.2 mi away from Roanoke. By plane, this route typically takes 7h 34m.

  • When did momondo last update prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to Santa Ana, California?

Best airlines flying from Roanoke to Santa Ana, California

Compare and see reviews for airlines that fly from Roanoke to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
7.8
8,508 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,941 reviews
Search American Airlines flights
United AirlinesPriceFrom $314Free CancellationRating
7.4
10,111 reviews
Search United Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Santa Ana for you.

Can I find flights from Roanoke to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Santa Ana?

Once you have performed a search for Roanoke to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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