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Cheap flights from Roanoke to Los Angeles from $219

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Los Angeles departing on 4/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Roanoke to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
$357Delta
Tue, Aug 18 - Tue, Sep 1
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
7:00 am - 11:50 pm
SNA
-
ROA
13h 50m
2 stops
$362Delta
Tue, Aug 18 - Tue, Aug 25
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
$392Delta
Tue, Aug 18 - Sun, Aug 30
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
7:05 pm - 10:35 am
SNA
-
ROA
12h 30m
2 stops
$411Delta
Tue, Aug 18 - Tue, Sep 1
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
$418Delta
Fri, Aug 21 - Sat, Sep 5
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
7:05 pm - 10:35 am
SNA
-
ROA
12h 30m
2 stops
$423Delta
Tue, Aug 18 - Sun, Aug 30
Delta Logo
3:25 pm - 10:14 pm
ROA
-
SNA
9h 49m
1 stop
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
$438Delta
Wed, Aug 19 - Sat, Sep 5
American Airlines Logo
2:54 pm - 9:14 pm
ROA
-
SNA
9h 20m
1 stop
American Airlines Logo
1:36 pm - 12:10 am
SNA
-
ROA
7h 34m
1 stop
$439American Airlines
Sat, Apr 25 - Tue, Apr 28
American Airlines Logo
6:00 am - 10:37 am
ROA
-
SNA
7h 37m
1 stop
American Airlines Logo
12:55 pm - 11:01 pm
SNA
-
ROA
7h 06m
1 stop
$442American Airlines
Wed, Jul 1 - Sat, Aug 1
Delta Logo
11:20 am - 6:20 pm
ROA
-
SNA
10h 00m
1 stop
Delta Logo
2:00 pm - 11:50 pm
SNA
-
ROA
6h 50m
1 stop
$443Delta
Thu, Aug 20 - Wed, Aug 26

American Airlines flights from Roanoke to Santa Ana

Our best American Airlines deals on Roanoke to Santa Ana flight tickets
American Airlines
Apr 25
ROA2:54 pmRoanoke
9h 20m
1 stop
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
Apr 28
SNA1:36 pmSanta Ana J. Wayne/Orange Cnty
7h 34m
1 stop
ROA12:10 amRoanoke
$439
American Airlines
Jul 1
ROA6:00 amRoanoke
7h 37m
1 stop
SNA10:37 amSanta Ana J. Wayne/Orange Cnty
Aug 1
SNA12:55 pmSanta Ana J. Wayne/Orange Cnty
7h 06m
1 stop
ROA11:01 pmRoanoke
$442
American Airlines
Apr 25
ROA11:09 amRoanoke
10h 20m
2 stops
SNA6:29 pmSanta Ana J. Wayne/Orange Cnty
Apr 28
SNA1:36 pmSanta Ana J. Wayne/Orange Cnty
7h 34m
1 stop
ROA12:10 amRoanoke
$444

United Airlines flights from Roanoke to Santa Ana

Our best United Airlines deals on Roanoke to Santa Ana flight tickets
United Airlines
Aug 22
ROA10:30 amRoanoke
10h 01m
2 stops
SNA5:31 pmSanta Ana J. Wayne/Orange Cnty
Sep 1
SNA8:40 amSanta Ana J. Wayne/Orange Cnty
12h 03m
2 stops
ROA11:43 pmRoanoke
$477
United Airlines
Aug 17
ROA5:47 pmRoanoke
7h 27m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
Sep 1
SNA10:48 amSanta Ana J. Wayne/Orange Cnty
7h 26m
1 stop
ROA9:14 pmRoanoke
$483
United Airlines
Aug 17
ROA5:47 pmRoanoke
7h 27m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
Sep 5
SNA7:49 pmSanta Ana J. Wayne/Orange Cnty
11h 03m
2 stops
ROA9:52 amRoanoke
$488

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Roanoke to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 8/18

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

2:00 pm-11:50 pm

1 stop6h 50m

$357

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 8/18

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

7:00 am-11:50 pm

2 stops13h 50m

$362

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 8/18

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Sun 8/30

2:00 pm-11:50 pm

1 stop6h 50m

$392

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 8/18

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

7:05 pm-10:35 am

2 stops12h 30m

$411

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Fri 8/21

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Sat 9/5

2:00 pm-11:50 pm

1 stop6h 50m

$418

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 8/18

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Sun 8/30

7:05 pm-10:35 am

2 stops12h 30m

$423

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 8/19

3:25 pm-10:14 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Sat 9/5

2:00 pm-11:50 pm

1 stop6h 50m

$438

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Sat 4/25

2:54 pm-9:14 pm

1 stop9h 20m

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

1:36 pm-12:10 am

1 stop7h 34m

$439
Quickest round-trip

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 7/1

6:00 am-10:37 am

1 stop7h 37m

Santa Ana J. Wayne/Orange Cnty

Sat 8/1

12:55 pm-11:01 pm

1 stop7h 06m

$442

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Thu 8/20

11:20 am-6:20 pm

1 stop10h 00m

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

2:00 pm-11:50 pm

1 stop6h 50m

$443

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Roanoke to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Roanoke to Santa Ana J. Wayne/Orange Cnty?

Allegiant Air, American Airlines, and United Airlines are the most popular carriers operating from Roanoke to Santa Ana J. Wayne/Orange Cnty

What airlines fly to Santa Ana?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Santa Ana from Roanoke according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Santa Ana. Keep in mind that there are 3 different airlines that fly to Santa Ana on a routine basis, so you have a few additional options to choose from.

When to book flights from Roanoke to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Santa Ana (ROA to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Santa Ana

Fastest flight time

7h 46m

Direct flights

None
The fastest flight from Roanoke to Santa Ana takes 7h 46m
There are no direct flights from Roanoke to Santa Ana. There are no popular flight routes from Roanoke to Santa Ana.
Search flight deals

Frequently asked questions about flying from Roanoke to Santa Ana

  • How far is Roanoke to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2131.2 mi away from Roanoke. By plane, this route typically takes 7h 46m.

  • When did momondo last update prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to Santa Ana?

Best airlines flying from Roanoke to Santa Ana

Compare and see reviews for airlines that fly from Roanoke to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
7.9
8,408 reviews
Search Delta flights
United AirlinesPriceFrom $308Free CancellationRating
7.4
9,574 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,570 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Santa Ana for you.

Can I find flights from Roanoke to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Santa Ana?

Once you have performed a search for Roanoke to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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