Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Roanoke to Los Angeles from $329

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Los Angeles departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Roanoke to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:56 pm - 8:02 pm
ROA
-
SNA
9h 06m1 stop
American Airlines Logo
9:01 am - 6:58 pm
SNA
-
ROA
6h 57m1 stop
$329American Airlines
Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
3:30 pm - 8:02 pm
ROA
-
SNA
7h 32m1 stop
American Airlines Logo
8:05 am - 8:31 pm
SNA
-
ROA
9h 26m2 stops
$334American Airlines
Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
12:43 pm - 10:56 pm
ROA
-
SNA
13h 13m2 stops
American Airlines Logo
8:05 am - 8:31 pm
SNA
-
ROA
9h 26m2 stops
$339American Airlines
Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
7:33 am - 2:23 pm
ROA
-
SNA
9h 50m1 stop
American Airlines Logo
7:45 am - 8:30 pm
SNA
-
ROA
9h 45m2 stops
$359American Airlines
Fri, Feb 20 - Mon, Feb 23
American Airlines Logo
8:15 am - 3:54 pm
ROA
-
SNA
10h 39m2 stops
American Airlines Logo
7:48 pm - 10:37 am
SNA
-
ROA
11h 49m2 stops
$364American Airlines
Thu, Feb 19 - Thu, Feb 26
American Airlines Logo
2:54 pm - 9:14 pm
ROA
-
SNA
9h 20m1 stop
American Airlines Logo
1:30 pm - 11:55 pm
SNA
-
ROA
7h 25m1 stop
$379American Airlines
Wed, Apr 22 - Wed, Apr 29
American Airlines Logo
2:54 pm - 9:14 pm
ROA
-
SNA
9h 20m1 stop
American Airlines Logo
12:27 pm - 11:55 pm
SNA
-
ROA
8h 28m2 stops
$384American Airlines
Wed, Apr 22 - Wed, Apr 29
United Airlines Logo
2:47 pm - 10:08 pm
ROA
-
SNA
10h 21m2 stops
United Airlines Logo
6:35 pm - 10:08 am
SNA
-
ROA
12h 33m2 stops
$439United Airlines
Fri, Feb 20 - Mon, Feb 23
American Airlines Logo
5:00 am - 12:40 pm
ROA
-
SNA
10h 40m2 stops
American Airlines Logo
12:27 pm - 11:55 pm
SNA
-
ROA
8h 28m2 stops
$452American Airlines
Wed, Apr 22 - Wed, Apr 29
United Airlines Logo
12:40 pm - 6:41 pm
ROA
-
SNA
9h 01m1 stop
United Airlines Logo
10:51 am - 9:11 pm
SNA
-
ROA
7h 20m1 stop
$459United Airlines
Sat, Jan 17 - Wed, Jan 21

American Airlines flights from Roanoke to Santa Ana, California

Our best American Airlines deals on Roanoke to Santa Ana, California flight tickets
American Airlines
Jan 20
ROA1:56 pmRoanoke
9h 06m
1 stop
SNA8:02 pmSanta Ana J. Wayne/Orange Cnty
Jan 27
SNA9:01 amSanta Ana J. Wayne/Orange Cnty
6h 57m
1 stop
ROA6:58 pmRoanoke
$329
Find similar
American Airlines
Jan 20
ROA3:30 pmRoanoke
7h 32m
1 stop
SNA8:02 pmSanta Ana J. Wayne/Orange Cnty
Jan 27
SNA8:05 amSanta Ana J. Wayne/Orange Cnty
9h 26m
2 stops
ROA8:31 pmRoanoke
$334
Find similar
American Airlines
Jan 20
ROA12:43 pmRoanoke
13h 13m
2 stops
SNA10:56 pmSanta Ana J. Wayne/Orange Cnty
Jan 27
SNA8:05 amSanta Ana J. Wayne/Orange Cnty
9h 26m
2 stops
ROA8:31 pmRoanoke
$339
Find similar

United Airlines flights from Roanoke to Santa Ana, California

Our best United Airlines deals on Roanoke to Santa Ana, California flight tickets
United Airlines
Feb 20
ROA2:47 pmRoanoke
10h 21m
2 stops
SNA10:08 pmSanta Ana J. Wayne/Orange Cnty
Feb 23
SNA6:35 pmSanta Ana J. Wayne/Orange Cnty
12h 33m
2 stops
ROA10:08 amRoanoke
$439
Find similar
United Airlines
Jan 17
ROA12:40 pmRoanoke
9h 01m
1 stop
SNA6:41 pmSanta Ana J. Wayne/Orange Cnty
Jan 21
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
7h 20m
1 stop
ROA9:11 pmRoanoke
$459
Find similar
United Airlines
Jan 17
ROA12:40 pmRoanoke
9h 01m
1 stop
SNA6:41 pmSanta Ana J. Wayne/Orange Cnty
Jan 21
SNA6:25 pmSanta Ana J. Wayne/Orange Cnty
14h 40m
2 stops
ROA12:05 pmRoanoke
$464
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Roanoke to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 1/20

1:56 pm-8:02 pm

1 stop9h 06m

Santa Ana J. Wayne/Orange Cnty

Tue 1/27

9:01 am-6:58 pm

1 stop6h 57m

$329

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 1/20

3:30 pm-8:02 pm

1 stop7h 32m

Santa Ana J. Wayne/Orange Cnty

Tue 1/27

8:05 am-8:31 pm

2 stops9h 26m

$334

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 1/20

12:43 pm-10:56 pm

2 stops13h 13m

Santa Ana J. Wayne/Orange Cnty

Tue 1/27

8:05 am-8:31 pm

2 stops9h 26m

$339

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Fri 2/20

7:33 am-2:23 pm

1 stop9h 50m

Santa Ana J. Wayne/Orange Cnty

Mon 2/23

7:45 am-8:30 pm

2 stops9h 45m

$359

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Thu 2/19

8:15 am-3:54 pm

2 stops10h 39m

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

7:48 pm-10:37 am

2 stops11h 49m

$364

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 4/22

2:54 pm-9:14 pm

1 stop9h 20m

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

1:30 pm-11:55 pm

1 stop7h 25m

$379

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 4/22

2:54 pm-9:14 pm

1 stop9h 20m

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

12:27 pm-11:55 pm

2 stops8h 28m

$384

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Fri 2/20

2:47 pm-10:08 pm

2 stops10h 21m

Santa Ana J. Wayne/Orange Cnty

Mon 2/23

6:35 pm-10:08 am

2 stops12h 33m

$439

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 4/22

5:00 am-12:40 pm

2 stops10h 40m

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

12:27 pm-11:55 pm

2 stops8h 28m

$452

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Sat 1/17

12:40 pm-6:41 pm

1 stop9h 01m

Santa Ana J. Wayne/Orange Cnty

Wed 1/21

10:51 am-9:11 pm

1 stop7h 20m

$459

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Roanoke to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, March is the cheapest month to fly from Roanoke to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $289. If you aren’t able to travel during the month of March, then book flights to Santa Ana, California from Roanoke during November instead. Flights to Santa Ana, California in November, while not as cheap as those in March, still average around $344.

When to book flights from Roanoke to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Santa Ana, California (ROA to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Santa Ana, California

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Roanoke to Santa Ana, California takes 7h 55m
There are no direct flights from Roanoke to Santa Ana, California. There are no popular flight routes from Roanoke to Santa Ana, California.
Search flight deals

  • How far is Roanoke to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2131.2 mi away from Roanoke. By plane, this route typically takes 7h 55m.

  • When did momondo last update prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to Santa Ana, California?

Best airlines flying from Roanoke to Santa Ana, California

Compare and see reviews for airlines that fly from Roanoke to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $308Free CancellationRating
7.4
9,124 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,074 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Santa Ana for you.

Can I find flights from Roanoke to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Santa Ana?

Once you have performed a search for Roanoke to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Santa Ana, California trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 1/30
Fri 2/6
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States