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Cheap flights from Roanoke to Los Angeles from $314

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Los Angeles departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Roanoke to Los Angeles

Cheap round-trip flights

American Airlines Logo
6:33 am - 2:11 pmROA-SNA
10h 38m1 stop
American Airlines Logo
9:59 am - 11:59 pmSNA-ROA
11h 00m2 stops
$314American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
American Airlines Logo
6:07 am - 2:09 pmROA-SNA
11h 02m2 stops
American Airlines Logo
9:59 am - 11:59 pmSNA-ROA
11h 00m2 stops
$319American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
American Airlines Logo
6:33 am - 2:11 pmROA-SNA
10h 38m1 stop
American Airlines Logo
8:55 am - 6:46 pmSNA-ROA
6h 51m1 stop
$349American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
Delta Logo
3:50 pm - 10:20 pmROA-SNA
9h 30m1 stop
Delta Logo
12:45 pm - 12:10 amSNA-ROA
8h 25m1 stop
$364Delta
Find Deal
Fri, Dec 5 - Sat, Dec 6
Delta Logo
3:50 pm - 10:20 pmROA-SNA
9h 30m1 stop
Delta Logo
8:00 am - 12:10 amSNA-ROA
13h 10m2 stops
$369Delta
Find Deal
Fri, Dec 5 - Sat, Dec 6
Delta Logo
7:05 am - 5:19 pmROA-SNA
13h 14m2 stops
Delta Logo
7:00 pm - 10:33 amSNA-ROA
12h 33m2 stops
$374Delta
Find Deal
Tue, Sep 30 - Fri, Oct 17
American Airlines Logo
4:06 pm - 8:24 pmROA-SNA
7h 18m1 stop
American Airlines Logo
11:55 am - 10:37 pmSNA-ROA
7h 42m1 stop
$409American Airlines
Find Deal
Wed, Feb 18 - Sat, Feb 21
United Airlines Logo
5:40 pm - 10:30 pmROA-SNA
7h 50m1 stop
United Airlines Logo
7:07 pm - 10:17 amSNA-ROA
12h 10m2 stops
$444United Airlines
Find Deal
Mon, Sep 29 - Sat, Oct 11
United Airlines Logo
10:30 am - 8:35 pmROA-SNA
13h 05m2 stops
United Airlines Logo
9:05 pm - 2:04 pmSNA-ROA
13h 59m2 stops
$449United Airlines
Find Deal
Mon, Sep 29 - Fri, Oct 17
United Airlines Logo
5:40 pm - 8:54 amROA-SNA
18h 14m2 stops
United Airlines Logo
9:05 pm - 9:47 amSNA-ROA
9h 42m2 stops
$483United Airlines
Find Deal
Sat, Oct 25 - Tue, Oct 28

American Airlines flights from Roanoke to Santa Ana

Our best American Airlines deals on Roanoke to Santa Ana flight tickets
American Airlines
Dec 10
ROA6:33 amRoanoke
10h 38m
1 stop
SNA2:11 pmSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA9:59 amSanta Ana J. Wayne/Orange Cnty
11h 00m
2 stops
ROA11:59 pmRoanoke
$314
Find similar
American Airlines
Dec 10
ROA6:07 amRoanoke
11h 02m
2 stops
SNA2:09 pmSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA9:59 amSanta Ana J. Wayne/Orange Cnty
11h 00m
2 stops
ROA11:59 pmRoanoke
$319
Find similar
American Airlines
Dec 10
ROA6:33 amRoanoke
10h 38m
1 stop
SNA2:11 pmSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
6h 51m
1 stop
ROA6:46 pmRoanoke
$349
Find similar

Delta flights from Roanoke to Santa Ana

Our best Delta deals on Roanoke to Santa Ana flight tickets
Delta
Dec 5
ROA3:50 pmRoanoke
9h 30m
1 stop
SNA10:20 pmSanta Ana J. Wayne/Orange Cnty
Dec 6
SNA12:45 pmSanta Ana J. Wayne/Orange Cnty
8h 25m
1 stop
ROA12:10 amRoanoke
$364
Find similar
Delta
Dec 5
ROA3:50 pmRoanoke
9h 30m
1 stop
SNA10:20 pmSanta Ana J. Wayne/Orange Cnty
Dec 6
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
13h 10m
2 stops
ROA12:10 amRoanoke
$369
Find similar
Delta
Sep 30
ROA7:05 amRoanoke
13h 14m
2 stops
SNA5:19 pmSanta Ana J. Wayne/Orange Cnty
Oct 17
SNA7:00 pmSanta Ana J. Wayne/Orange Cnty
12h 33m
2 stops
ROA10:33 amRoanoke
$374
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Roanoke to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 12/10

6:33 am-2:11 pm

1 stop10h 38m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

9:59 am-11:59 pm

2 stops11h 00m

$314

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 12/10

6:07 am-2:09 pm

2 stops11h 02m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

9:59 am-11:59 pm

2 stops11h 00m

$319

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 12/10

6:33 am-2:11 pm

1 stop10h 38m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

8:55 am-6:46 pm

1 stop6h 51m

$349

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Fri 12/5

3:50 pm-10:20 pm

1 stop9h 30m

Santa Ana J. Wayne/Orange Cnty

Sat 12/6

12:45 pm-12:10 am

1 stop8h 25m

$364

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Fri 12/5

3:50 pm-10:20 pm

1 stop9h 30m

Santa Ana J. Wayne/Orange Cnty

Sat 12/6

8:00 am-12:10 am

2 stops13h 10m

$369

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 9/30

7:05 am-5:19 pm

2 stops13h 14m

Santa Ana J. Wayne/Orange Cnty

Fri 10/17

7:00 pm-10:33 am

2 stops12h 33m

$374

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 2/18

4:06 pm-8:24 pm

1 stop7h 18m

Santa Ana J. Wayne/Orange Cnty

Sat 2/21

11:55 am-10:37 pm

1 stop7h 42m

$409

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Mon 9/29

5:40 pm-10:30 pm

1 stop7h 50m

Santa Ana J. Wayne/Orange Cnty

Sat 10/11

7:07 pm-10:17 am

2 stops12h 10m

$444

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Mon 9/29

10:30 am-8:35 pm

2 stops13h 05m

Santa Ana J. Wayne/Orange Cnty

Fri 10/17

9:05 pm-2:04 pm

2 stops13h 59m

$449

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Sat 10/25

5:40 pm-8:54 am

2 stops18h 14m

Santa Ana J. Wayne/Orange Cnty

Tue 10/28

9:05 pm-9:47 am

2 stops9h 42m

$483

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Roanoke is in February. Flight prices, which tend to average around $369, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Santa Ana, with average flight prices from Roanoke averaging around $384.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Roanoke is on a Saturday. momondo users have found tickets for Saturday departures for as low as $463. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Roanoke because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $993.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Roanoke to Santa Ana flights are usually those with departure times in the morning. Our users have found flights to Santa Ana in the morning for as low as $572. Try not to purchase tickets in the afternoon because they tend to be around $713. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Roanoke to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Santa Ana (ROA to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Santa Ana

Direct flights

None
There are no direct flights from Roanoke to Santa Ana. There are no popular flight routes from Roanoke to Santa Ana.
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  • How far is Roanoke to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2131.2 mi away from Roanoke. By plane, this route typically takes 7h 18m.

  • When did momondo last update prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to Santa Ana?

Best airlines flying from Roanoke to Santa Ana

Compare and see reviews for airlines that fly from Roanoke to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $308Free CancellationRating
7.4
8,931 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $333Free CancellationRating
7.9
7,956 reviews
Search Delta flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
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Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Santa Ana for you.

Can I find flights from Roanoke to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Santa Ana?

Once you have performed a search for Roanoke to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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