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Cheap flights from Roanoke to Los Angeles from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Los Angeles departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Roanoke to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:53 am - 2:11 pmROA-SNA
10h 18m1 stop
American Airlines Logo
8:55 am - 9:37 pmSNA-ROA
9h 42m1 stop
$309American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
American Airlines Logo
12:58 pm - 9:41 pmROA-SNA
11h 43m2 stops
American Airlines Logo
8:55 am - 9:37 pmSNA-ROA
9h 42m1 stop
$314American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
American Airlines Logo
12:58 pm - 9:41 pmROA-SNA
11h 43m2 stops
American Airlines Logo
12:28 pm - 11:59 pmSNA-ROA
8h 31m2 stops
$319American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
Delta Logo
3:47 pm - 10:14 pmROA-SNA
9h 27m1 stop
Delta Logo
9:51 am - 12:06 amSNA-ROA
11h 15m2 stops
$339Delta
Find Deal
Mon, Jan 26 - Tue, Feb 3
Delta Logo
7:05 am - 8:03 pmROA-SNA
15h 58m2 stops
Delta Logo
9:51 am - 12:06 amSNA-ROA
11h 15m2 stops
$344Delta
Find Deal
Tue, Jan 27 - Tue, Feb 3
Delta Logo
3:47 pm - 10:14 pmROA-SNA
9h 27m1 stop
Delta Logo
11:15 am - 10:44 amSNA-ROA
20h 29m2 stops
$358Delta
Find Deal
Mon, Jan 26 - Mon, Feb 2
United Airlines Logo
6:45 am - 11:51 amROA-SNA
8h 06m1 stop
United Airlines Logo
10:51 am - 9:44 pmSNA-ROA
7h 53m1 stop
$409United Airlines
Find Deal
Tue, Jan 27 - Tue, Feb 3
United Airlines Logo
12:40 pm - 9:18 pmROA-SNA
11h 38m2 stops
United Airlines Logo
10:51 am - 9:44 pmSNA-ROA
7h 53m1 stop
$414United Airlines
Find Deal
Wed, Jan 28 - Sat, Feb 7
United Airlines Logo
2:55 pm - 10:24 pmROA-SNA
10h 29m2 stops
United Airlines Logo
9:10 pm - 2:09 pmSNA-ROA
13h 59m2 stops
$419United Airlines
Find Deal
Mon, Jan 26 - Thu, Feb 5
American Airlines Logo
8:12 am - 3:55 pmROA-SNA
10h 43m2 stops
American Airlines Logo
6:45 am - 8:30 pmSNA-ROA
10h 45m2 stops
$492American Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 15

American Airlines flights from Roanoke to Santa Ana, California

Our best American Airlines deals on Roanoke to Santa Ana, California flight tickets
American Airlines
Dec 10
ROA6:53 amRoanoke
10h 18m
1 stop
SNA2:11 pmSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
9h 42m
1 stop
ROA9:37 pmRoanoke
$309
Find similar
American Airlines
Dec 10
ROA12:58 pmRoanoke
11h 43m
2 stops
SNA9:41 pmSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
9h 42m
1 stop
ROA9:37 pmRoanoke
$314
Find similar
American Airlines
Dec 10
ROA12:58 pmRoanoke
11h 43m
2 stops
SNA9:41 pmSanta Ana J. Wayne/Orange Cnty
Dec 16
SNA12:28 pmSanta Ana J. Wayne/Orange Cnty
8h 31m
2 stops
ROA11:59 pmRoanoke
$319
Find similar

Delta flights from Roanoke to Santa Ana, California

Our best Delta deals on Roanoke to Santa Ana, California flight tickets
Delta
Jan 26
ROA3:47 pmRoanoke
9h 27m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
Feb 3
SNA9:51 amSanta Ana J. Wayne/Orange Cnty
11h 15m
2 stops
ROA12:06 amRoanoke
$339
Find similar
Delta
Jan 27
ROA7:05 amRoanoke
15h 58m
2 stops
SNA8:03 pmSanta Ana J. Wayne/Orange Cnty
Feb 3
SNA9:51 amSanta Ana J. Wayne/Orange Cnty
11h 15m
2 stops
ROA12:06 amRoanoke
$344
Find similar
Delta
Jan 26
ROA3:47 pmRoanoke
9h 27m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
Feb 2
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
20h 29m
2 stops
ROA10:44 amRoanoke
$358
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Roanoke to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 12/10

6:53 am-2:11 pm

1 stop10h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

8:55 am-9:37 pm

1 stop9h 42m

$309

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 12/10

12:58 pm-9:41 pm

2 stops11h 43m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

8:55 am-9:37 pm

1 stop9h 42m

$314

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 12/10

12:58 pm-9:41 pm

2 stops11h 43m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

12:28 pm-11:59 pm

2 stops8h 31m

$319

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Mon 1/26

3:47 pm-10:14 pm

1 stop9h 27m

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

9:51 am-12:06 am

2 stops11h 15m

$339

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 1/27

7:05 am-8:03 pm

2 stops15h 58m

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

9:51 am-12:06 am

2 stops11h 15m

$344

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Mon 1/26

3:47 pm-10:14 pm

1 stop9h 27m

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

11:15 am-10:44 am

2 stops20h 29m

$358

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Tue 1/27

6:45 am-11:51 am

1 stop8h 06m

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

10:51 am-9:44 pm

1 stop7h 53m

$409

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Wed 1/28

12:40 pm-9:18 pm

2 stops11h 38m

Santa Ana J. Wayne/Orange Cnty

Sat 2/7

10:51 am-9:44 pm

1 stop7h 53m

$414

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Mon 1/26

2:55 pm-10:24 pm

2 stops10h 29m

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

9:10 pm-2:09 pm

2 stops13h 59m

$419

RoanokeSanta Ana

ROA - SNA

ROASNA

Roanoke

Thu 12/4

8:12 am-3:55 pm

2 stops10h 43m

Santa Ana J. Wayne/Orange Cnty

Mon 12/15

6:45 am-8:30 pm

2 stops10h 45m

$492

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, March is the cheapest month to fly from Roanoke to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $289. If you aren’t able to travel during the month of March, then book flights to Santa Ana, California from Roanoke during November instead. Flights to Santa Ana, California in November, while not as cheap as those in March, still average around $344.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Roanoke to Santa Ana, California is on a Saturday. Travelers who choose to depart for Santa Ana, California on a Saturday will often find tickets for as low as $463. The most expensive day to fly to Santa Ana, California is Sunday, with ticket prices averaging around $993.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the morning is the cheapest time of day to fly from Roanoke to Santa Ana, California when you can find flight prices for as low as $572. Flying to Santa Ana, California in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the afternoon when prices are around $713.

When to book flights from Roanoke to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Santa Ana, California (ROA to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Santa Ana, California

Direct flights

None
There are no direct flights from Roanoke to Santa Ana, California. There are no popular flight routes from Roanoke to Santa Ana, California.
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  • How far is Roanoke to Santa Ana J. Wayne/Orange Cnty by plane?

    Santa Ana J. Wayne/Orange Cnty is 2131.2 mi away from Roanoke. By plane, this route typically takes 7h 32m.

  • When did momondo last update prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to Santa Ana, California?

Best airlines flying from Roanoke to Santa Ana, California

Compare and see reviews for airlines that fly from Roanoke to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $308Free CancellationRating
7.4
9,012 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Santa Ana for you.

Can I find flights from Roanoke to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Santa Ana?

Once you have performed a search for Roanoke to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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