Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Roanoke to San Francisco from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Francisco departing on 10/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Roanoke to San Francisco

Cheap round-trip flights

American Airlines Logo
2:38 pm - 9:56 pmROA-SFO
10h 18m1 stop
American Airlines Logo
9:35 am - 8:29 pmSFO-ROA
7h 54m1 stop
$309American Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
American Airlines Logo
2:38 pm - 8:44 pmROA-SFO
9h 06m1 stop
American Airlines Logo
11:25 pm - 12:18 pmSFO-ROA
9h 53m2 stops
$314American Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
United Airlines Logo
5:40 pm - 10:31 pmROA-SFO
7h 51m1 stop
United Airlines Logo
6:30 am - 6:45 pmSFO-ROA
9h 15m1 stop
$339United Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
American Airlines Logo
6:00 am - 1:10 pmROA-SFO
10h 10m2 stops
American Airlines Logo
12:51 pm - 11:05 pmSFO-ROA
7h 14m1 stop
$344American Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
United Airlines Logo
7:55 pm - 1:17 amROA-SFO
8h 22m1 stop
United Airlines Logo
7:00 am - 5:10 pmSFO-ROA
7h 10m1 stop
$353United Airlines
Find Deal
Wed, Dec 24 - Wed, Dec 31
American Airlines Logo
2:24 pm - 9:46 pmROA-SFO
10h 22m1 stop
American Airlines Logo
6:00 am - 4:23 pmSFO-ROA
7h 23m1 stop
$369American Airlines
Find Deal
Fri, Sep 26 - Sun, Sep 28
United Airlines Logo
3:00 pm - 9:47 pmROA-SFO
9h 47m1 stop
United Airlines Logo
11:20 pm - 9:47 amSFO-ROA
7h 27m1 stop
$409United Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
Delta Logo
6:57 pm - 11:49 pmROA-SFO
7h 52m1 stop
Delta Logo
2:05 pm - 12:05 amSFO-ROA
7h 00m1 stop
$508Delta
Find Deal
Tue, Dec 23 - Sat, Jan 3
Delta Logo
6:57 pm - 8:26 amROA-SFO
16h 29m2 stops
Delta Logo
2:05 pm - 12:05 amSFO-ROA
7h 00m1 stop
$542Delta
Find Deal
Tue, Dec 23 - Sat, Jan 3
Delta Logo
6:57 pm - 11:49 pmROA-SFO
7h 52m1 stop
Delta Logo
8:00 am - 8:37 pmSFO-ROA
9h 37m1 stop
$543Delta
Find Deal
Tue, Dec 23 - Thu, Jan 1

American Airlines flights from Roanoke to San Francisco

Our best American Airlines deals on Roanoke to San Francisco flight tickets
American Airlines
Oct 22
ROA2:38 pmRoanoke
10h 18m
1 stop
SFO9:56 pmSan Francisco
Oct 29
SFO9:35 amSan Francisco
7h 54m
1 stop
ROA8:29 pmRoanoke
$309
Find similar
American Airlines
Oct 22
ROA2:38 pmRoanoke
9h 06m
1 stop
SFO8:44 pmSan Francisco
Oct 29
SFO11:25 pmSan Francisco
9h 53m
2 stops
ROA12:18 pmRoanoke
$314
Find similar
American Airlines
Sep 30
ROA6:00 amRoanoke
10h 10m
2 stops
SFO1:10 pmSan Francisco
Oct 7
SFO12:51 pmSan Francisco
7h 14m
1 stop
ROA11:05 pmRoanoke
$344
Find similar

United Airlines flights from Roanoke to San Francisco

Our best United Airlines deals on Roanoke to San Francisco flight tickets
United Airlines
Sep 30
ROA5:40 pmRoanoke
7h 51m
1 stop
SFO10:31 pmSan Francisco
Oct 7
SFO6:30 amSan Francisco
9h 15m
1 stop
ROA6:45 pmRoanoke
$339
Find similar
United Airlines
Dec 24
ROA7:55 pmRoanoke
8h 22m
1 stop
SFO1:17 amSan Francisco
Dec 31
SFO7:00 amSan Francisco
7h 10m
1 stop
ROA5:10 pmRoanoke
$353
Find similar
United Airlines
Oct 22
ROA3:00 pmRoanoke
9h 47m
1 stop
SFO9:47 pmSan Francisco
Oct 29
SFO11:20 pmSan Francisco
7h 27m
1 stop
ROA9:47 amRoanoke
$409
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 10/22

2:38 pm-9:56 pm

1 stop10h 18m

San Francisco

Wed 10/29

9:35 am-8:29 pm

1 stop7h 54m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 10/22

2:38 pm-8:44 pm

1 stop9h 06m

San Francisco

Wed 10/29

11:25 pm-12:18 pm

2 stops9h 53m

$314

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 9/30

5:40 pm-10:31 pm

1 stop7h 51m

San Francisco

Tue 10/7

6:30 am-6:45 pm

1 stop9h 15m

$339

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 9/30

6:00 am-1:10 pm

2 stops10h 10m

San Francisco

Tue 10/7

12:51 pm-11:05 pm

1 stop7h 14m

$344

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 12/24

7:55 pm-1:17 am

1 stop8h 22m

San Francisco

Wed 12/31

7:00 am-5:10 pm

1 stop7h 10m

$353

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Fri 9/26

2:24 pm-9:46 pm

1 stop10h 22m

San Francisco

Sun 9/28

6:00 am-4:23 pm

1 stop7h 23m

$369

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 10/22

3:00 pm-9:47 pm

1 stop9h 47m

San Francisco

Wed 10/29

11:20 pm-9:47 am

1 stop7h 27m

$409

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 12/23

6:57 pm-11:49 pm

1 stop7h 52m

San Francisco

Sat 1/3

2:05 pm-12:05 am

1 stop7h 00m

$508

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 12/23

6:57 pm-8:26 am

2 stops16h 29m

San Francisco

Sat 1/3

2:05 pm-12:05 am

1 stop7h 00m

$542

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 12/23

6:57 pm-11:49 pm

1 stop7h 52m

San Francisco

Thu 1/1

8:00 am-8:37 pm

1 stop9h 37m

$543

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Roanoke to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of June, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $418.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Roanoke to San Francisco is on a Wednesday when prices can be found for as low as $448. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $722.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Roanoke to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $441. Flights at noon are often more expensive with an average ticket price of $602.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $515 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Roanoke for as low as $333 on momondo.

How have Roanoke to San Francisco flight prices changed over time?

As of September 2025, prices for Roanoke to San Francisco flights are approximately 31% cheaper when compared to flights at the same time last year.

When to book flights from Roanoke to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to San Francisco (ROA to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Francisco

Direct flights

None
There are no direct flights from Roanoke to San Francisco. There are no popular flight routes from Roanoke to San Francisco.
Search flight deals

  • How far is Roanoke to San Francisco by plane?

    A flight from Roanoke to San Francisco will travel around 2305.3 mi. Typically, this will take 7h 51m by plane in normal conditions.

  • When did momondo last update prices for flights from Roanoke Airport to San Francisco Airport?

    Prices for flights from Roanoke Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to San Francisco Airport?

  • How old do you have to be to fly from Roanoke Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to San Francisco?

Best airlines flying from Roanoke to San Francisco

Compare and see reviews for airlines that fly from Roanoke to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $282Free CancellationRating
7.9
7,959 reviews
Search Delta flights
United AirlinesPriceFrom $308Free CancellationRating
7.4
8,934 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Calistoga
Hayward
Bodega Bay
Roseville
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Walnut Creek
Half Moon Bay
Vallejo
South San Francisco
Redwood City
Fairfield
Salinas

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Roanoke with this policy.

How can momondo help me find flights from Roanoke to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Roanoke to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 10/14
Tue 10/21
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States