Cheap flights from Roanoke to San Francisco from $357
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Francisco departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Sat 11/7
6:10 am-12:23 pm
1 stop9h 13m
San Francisco
Sat 11/14
9:50 pm-10:30 am
1 stop9h 40m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Wed 12/16
4:52 pm-12:07 am
1 stop10h 15m
San Francisco
Wed 1/13
11:12 am-10:59 pm
1 stop8h 47m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Wed 11/4
6:30 am-11:50 am
1 stop8h 20m
San Francisco
Sat 11/7
10:45 pm-9:26 am
1 stop7h 41m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Tue 11/24
2:55 pm-9:29 pm
1 stop9h 34m
San Francisco
Tue 12/1
11:40 pm-10:01 am
1 stop7h 21m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Wed 2/3
5:09 pm-11:51 pm
1 stop9h 42m
San Francisco
Tue 2/9
12:49 pm-10:59 pm
1 stop7h 10m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Wed 2/3
5:09 pm-11:51 pm
1 stop9h 42m
San Francisco
Tue 2/9
8:30 am-8:31 pm
1 stop9h 01m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Tue 11/24
2:55 pm-8:35 pm
1 stop8h 40m
San Francisco
Tue 12/1
11:10 pm-10:01 am
1 stop7h 51m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Thu 12/3
3:38 pm-10:48 pm
1 stop10h 10m
San Francisco
Tue 12/8
11:49 am-12:26 am
1 stop9h 37m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Thu 12/3
3:38 pm-10:48 pm
1 stop10h 10m
San Francisco
Wed 12/9
11:59 pm-10:37 am
1 stop7h 38m
RoanokeSan Francisco
ROA Roanoke - SFO San Francisco
ROASFO
Roanoke
Thu 12/3
6:55 pm-11:59 pm
1 stop8h 04m
San Francisco
Fri 12/11
2:00 pm-12:26 am
1 stop7h 26m
See travel insights to San Francisco from
How to get the cheapest flight ticket from Roanoke to San Francisco
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Roanoke and San Francisco?
Prices are currently low for flights on this route.
Typical prices usually range from $395 to $507.The lowest price recently found on this route was $393.
What is the cheapest month to fly to San Francisco?
If you aren’t able to travel to San Francisco during the month of October, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $408.
How far in advance should I book a flight from Roanoke to San Francisco?
You are more likely to see cheaper flights to San Francisco from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $515 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Roanoke for as low as $330 on momondo.
What is the cheapest airline that flies from Roanoke to San Francisco?
United Airlines and Delta are the most popular carriers operating from Roanoke to San Francisco
What airlines fly to San Francisco?
American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Francisco from Roanoke according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 3 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.
Which airport is the most popular layover for flights between Roanoke and San Francisco?
Chicago (ORD) was the most common stop: 44% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from Roanoke to San Francisco?
Flights via Atlanta (ATL) offer the lowest average round-trip price of $434.
Which layover airport has the shortest travel time from Roanoke to San Francisco?
Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 8h 50m.
Which layover airport has the shortest connection time from Roanoke to San Francisco?
Charlotte (CLT) has the shortest average layover time for this route: 1h 17m.
When to book flights from Roanoke to San Francisco
Cheap Roanoke to San Francisco (ROA to SFO) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Francisco
Frequently asked questions about flying from Roanoke to San Francisco
How far is Roanoke to San Francisco by plane?
A flight from Roanoke to San Francisco will travel around 2304.9 mi. Typically, this will take 8h 49m by plane in normal conditions.
When did momondo last update prices for flights from Roanoke Airport to San Francisco Airport?
Prices for flights from Roanoke Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Roanoke Airport to San Francisco Airport?
As of October 2026, there are 3 operators available to choose from for flights from Roanoke Airport to San Francisco Airport.
How old do you have to be to fly from Roanoke Airport to San Francisco Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Roanoke to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Roanoke to San Francisco is American Airlines, representing 53% of all bookings. The subsequent popular airlines are United Airlines at 38% and Delta at 10%.
Best airlines flying from Roanoke to San Francisco
Compare and see reviews for airlines that fly from Roanoke to San Francisco with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $318 | Free Cancellation | Rating 7.8 8,646 reviews | |||
| PriceFrom $338 | Free Cancellation | Rating 7.4 10,322 reviews | |||
| PriceFrom $348 | Free Cancellation | Rating 7.0 12,146 reviews |
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Roanoke to San Francisco?
momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to San Francisco. momondo saves you time and could save you money on your trip.
Can I find flights from Roanoke to San Francisco with flexible booking policies on momondo?
Yes. momondo enables you to select and highlight flights to San Francisco from Roanoke with this policy.
How can momondo help me find flights from Roanoke to San Francisco?
momondo provides multiple filters to help you find the best flight to San Francisco from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.
I’m not ready to book a flight from Roanoke to San Francisco right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to San Francisco from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.