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Cheap flights from Roanoke to San Francisco from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Francisco departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 10:12 am
ROA
-
SFO
7h 12m
1 stop
Delta Logo
1:45 pm - 11:50 pm
SFO
-
ROA
7h 05m
1 stop
$323Delta
Wed, Aug 12 - Wed, Aug 19
American Airlines Logo
6:38 am - 1:12 pm
ROA
-
SFO
9h 34m
2 stops
American Airlines Logo
8:00 am - 9:10 pm
SFO
-
ROA
10h 10m
1 stop
$328American Airlines
Wed, Aug 19 - Wed, Aug 26
United Airlines Logo
5:47 pm - 10:56 pm
ROA
-
SFO
8h 09m
1 stop
United Airlines Logo
10:35 pm - 9:44 am
SFO
-
ROA
8h 09m
1 stop
$346United Airlines
Sat, Sep 12 - Fri, Sep 18
American Airlines Logo
4:00 pm - 10:20 pm
ROA
-
SFO
9h 20m
2 stops
American Airlines Logo
5:51 am - 3:51 pm
SFO
-
ROA
7h 00m
1 stop
$348American Airlines
Sat, Sep 19 - Wed, Sep 23
Delta Logo
6:00 am - 10:12 am
ROA
-
SFO
7h 12m
1 stop
Delta Logo
1:45 pm - 11:50 pm
SFO
-
ROA
7h 05m
1 stop
$357Delta
Wed, Aug 12 - Wed, Aug 19
American Airlines Logo
2:49 pm - 8:10 pm
ROA
-
SFO
8h 21m
1 stop
American Airlines Logo
12:18 am - 2:24 pm
SFO
-
ROA
11h 06m
1 stop
$366American Airlines
Thu, May 28 - Sat, May 30
American Airlines Logo
6:02 pm - 10:49 pm
ROA
-
SFO
7h 47m
1 stop
American Airlines Logo
12:59 am - 2:24 pm
SFO
-
ROA
10h 25m
1 stop
$386American Airlines
Tue, Jun 23 - Mon, Jun 29
American Airlines Logo
6:38 am - 1:12 pm
ROA
-
SFO
9h 34m
2 stops
American Airlines Logo
11:00 am - 10:50 pm
SFO
-
ROA
8h 50m
1 stop
$394American Airlines
Wed, Aug 12 - Wed, Aug 19
American Airlines Logo
6:38 am - 1:12 pm
ROA
-
SFO
9h 34m
2 stops
American Airlines Logo
9:05 am - 10:50 pm
SFO
-
ROA
10h 45m
2 stops
$396American Airlines
Wed, Aug 19 - Wed, Aug 26
American Airlines Logo
4:29 pm - 10:49 pm
ROA
-
SFO
9h 20m
1 stop
American Airlines Logo
12:59 am - 2:24 pm
SFO
-
ROA
10h 25m
1 stop
$406American Airlines
Fri, May 29 - Thu, Jun 4

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Delta flights from Roanoke to San Francisco

Our best Delta deals on Roanoke to San Francisco flight tickets
Delta
Aug 12
ROA6:00 amRoanoke
7h 12m
1 stop
SFO10:12 amSan Francisco
Aug 19
SFO1:45 pmSan Francisco
7h 05m
1 stop
ROA11:50 pmRoanoke
$323
Delta
Aug 12
ROA6:00 amRoanoke
7h 12m
1 stop
SFO10:12 amSan Francisco
Aug 19
SFO1:45 pmSan Francisco
7h 05m
1 stop
ROA11:50 pmRoanoke
$357
Delta
Sep 29
ROA3:25 pmRoanoke
11h 21m
2 stops
SFO11:46 pmSan Francisco
Oct 3
SFO7:30 amSan Francisco
8h 46m
1 stop
ROA7:16 pmRoanoke
$414

American Airlines flights from Roanoke to San Francisco

Our best American Airlines deals on Roanoke to San Francisco flight tickets
American Airlines
Aug 19
ROA6:38 amRoanoke
9h 34m
2 stops
SFO1:12 pmSan Francisco
Aug 26
SFO8:00 amSan Francisco
10h 10m
1 stop
ROA9:10 pmRoanoke
$328
American Airlines
Sep 19
ROA4:00 pmRoanoke
9h 20m
2 stops
SFO10:20 pmSan Francisco
Sep 23
SFO5:51 amSan Francisco
7h 00m
1 stop
ROA3:51 pmRoanoke
$348
American Airlines
May 28
ROA2:49 pmRoanoke
8h 21m
1 stop
SFO8:10 pmSan Francisco
May 30
SFO12:18 amSan Francisco
11h 06m
1 stop
ROA2:24 pmRoanoke
$366

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 8/12

6:00 am-10:12 am

1 stop7h 12m

San Francisco

Wed 8/19

1:45 pm-11:50 pm

1 stop7h 05m

$323

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 8/19

6:38 am-1:12 pm

2 stops9h 34m

San Francisco

Wed 8/26

8:00 am-9:10 pm

1 stop10h 10m

$328

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 9/12

5:47 pm-10:56 pm

1 stop8h 09m

San Francisco

Fri 9/18

10:35 pm-9:44 am

1 stop8h 09m

$346

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 9/19

4:00 pm-10:20 pm

2 stops9h 20m

San Francisco

Wed 9/23

5:51 am-3:51 pm

1 stop7h 00m

$348

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 8/12

6:00 am-10:12 am

1 stop7h 12m

San Francisco

Wed 8/19

1:45 pm-11:50 pm

1 stop7h 05m

$357

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 5/28

2:49 pm-8:10 pm

1 stop8h 21m

San Francisco

Sat 5/30

12:18 am-2:24 pm

1 stop11h 06m

$366

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 6/23

6:02 pm-10:49 pm

1 stop7h 47m

San Francisco

Mon 6/29

12:59 am-2:24 pm

1 stop10h 25m

$386

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 8/12

6:38 am-1:12 pm

2 stops9h 34m

San Francisco

Wed 8/19

11:00 am-10:50 pm

1 stop8h 50m

$394

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 8/19

6:38 am-1:12 pm

2 stops9h 34m

San Francisco

Wed 8/26

9:05 am-10:50 pm

2 stops10h 45m

$396

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Fri 5/29

4:29 pm-10:49 pm

1 stop9h 20m

San Francisco

Thu 6/4

12:59 am-2:24 pm

1 stop10h 25m

$406

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Roanoke and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of January, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $407.

How far in advance should I book a flight from Roanoke to San Francisco?

You are more likely to see cheaper flights to San Francisco from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $471 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Roanoke for as low as $348 on momondo.

When to book flights from Roanoke to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to San Francisco (ROA to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Francisco

Fastest flight time

7h 12m

Direct flights

None
The fastest flight from Roanoke to San Francisco takes 7h 12m
There are no direct flights from Roanoke to San Francisco. There are no popular flight routes from Roanoke to San Francisco.
Search flight deals

Frequently asked questions about flying from Roanoke to San Francisco

  • How far is Roanoke to San Francisco by plane?

    A flight from Roanoke to San Francisco will travel around 2304.9 mi. Typically, this will take 7h 12m by plane in normal conditions.

  • When did momondo last update prices for flights from Roanoke Airport to San Francisco Airport?

    Prices for flights from Roanoke Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to San Francisco Airport?

  • How old do you have to be to fly from Roanoke Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to San Francisco?

Best airlines flying from Roanoke to San Francisco

Compare and see reviews for airlines that fly from Roanoke to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $308Free CancellationRating
7.4
9,682 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,672 reviews
Search American Airlines flights
DeltaPriceFrom $308Free CancellationRating
7.9
8,460 reviews
Search Delta flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Vallejo
Fremont
Big Sur
Calistoga
Daly City
South San Francisco
Pacific Grove
Sunnyvale
Salinas
Milpitas

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Roanoke with this policy.

How can momondo help me find flights from Roanoke to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Roanoke to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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