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Cheap flights from Roanoke to San Francisco from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Francisco departing on 9/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:25 pm - 9:35 pmROA  Roanoke-SFO San Francisco
9h 10m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:45 pm - 10:34 amSFO  San Francisco-ROA Roanoke
7h 49m1 stop Atlanta Hartsfield-Jackson
$373Delta
Sat, Feb 6 - Tue, Feb 16
Delta Logo
4:46 pm - 11:57 pmROA  Roanoke-SFO San Francisco
10h 11m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 11:59 pmSFO  San Francisco-ROA Roanoke
6h 59m1 stop Atlanta Hartsfield-Jackson
$373Delta
Sat, Sep 12 - Tue, Sep 15
American Airlines Logo
6:20 am - 10:52 amROA  Roanoke-SFO San Francisco
7h 32m1 stop Charlotte Douglas
American Airlines Logo
6:00 am - 5:17 pmSFO  San Francisco-ROA Roanoke
8h 17m1 stop Chicago O'Hare Intl
$373American Airlines
Tue, Sep 22 - Wed, Sep 30
American Airlines Logo
8:15 am - 3:43 pmROA  Roanoke-SFO San Francisco
10h 28m1 stop Charlotte Douglas
American Airlines Logo
6:00 am - 4:26 pmSFO  San Francisco-ROA Roanoke
7h 26m1 stop Chicago O'Hare Intl
$373American Airlines
Sat, Oct 31 - Tue, Dec 1
United Airlines Logo
10:30 am - 5:25 pmROA  Roanoke-SFO San Francisco
9h 55m1 stop Chicago O'Hare Intl
United Airlines Logo
11:30 pm - 9:29 amSFO  San Francisco-ROA Roanoke
6h 59m1 stop Chicago O'Hare Intl
$373United Airlines
Tue, Nov 3 - Sat, Nov 7
American Airlines Logo
5:10 pm - 10:14 pmROA  Roanoke-SFO San Francisco
8h 04m1 stop Charlotte Douglas
American Airlines Logo
9:00 am - 9:15 pmSFO  San Francisco-ROA Roanoke
9h 15m1 stop Charlotte Douglas
$373American Airlines
Wed, Feb 3 - Tue, Feb 9
Delta Logo
6:00 am - 11:59 amROA  Roanoke-SFO San Francisco
8h 59m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:00 pm - 12:23 amSFO  San Francisco-ROA Roanoke
7h 23m1 stop Atlanta Hartsfield-Jackson
$373Delta
Tue, Feb 9 - Tue, Feb 16
Delta Logo
3:25 pm - 9:35 pmROA  Roanoke-SFO San Francisco
9h 10m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:30 pm - 10:34 amSFO  San Francisco-ROA Roanoke
10h 04m1 stop Atlanta Hartsfield-Jackson
$373Delta
Sat, Feb 6 - Wed, Feb 10
United Airlines Logo
3:00 pm - 8:49 pmROA  Roanoke-SFO San Francisco
8h 49m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
11:30 pm - 10:11 amSFO  San Francisco-ROA Roanoke
7h 41m1 stop Chicago O'Hare Intl
$376United Airlines
Mon, Feb 8 - Sat, Feb 13
United Airlines Logo
8:05 pm - 12:59 amROA  Roanoke-SFO San Francisco
7h 54m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
11:30 pm - 9:57 amSFO  San Francisco-ROA Roanoke
7h 27m1 stop Chicago O'Hare Intl
$376United Airlines
Sat, Sep 12 - Sun, Sep 27

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United Airlines flights from Roanoke to San Francisco

Our best United Airlines deals on Roanoke to San Francisco flight tickets
United Airlines
Sep 8
ROA8:05 pmRoanoke
7h 54m
1 stop
SFO12:59 amSan Francisco
Sep 15
SFO11:30 pmSan Francisco
7h 29m
1 stop
ROA9:59 amRoanoke
$462
United Airlines
Sep 8
ROA5:51 pmRoanoke
9h 39m
1 stop
SFO12:30 amSan Francisco
Sep 22
SFO6:00 amSan Francisco
8h 07m
1 stop
ROA5:07 pmRoanoke
$466
United Airlines
Nov 14
ROA10:33 amRoanoke
10h 14m
1 stop
SFO5:47 pmSan Francisco
Nov 17
SFO10:50 amSan Francisco
9h 54m
1 stop
ROA11:44 pmRoanoke
$483

American Airlines flights from Roanoke to San Francisco

Our best American Airlines deals on Roanoke to San Francisco flight tickets
American Airlines
Oct 31
ROA8:15 amRoanoke
10h 28m
1 stop
SFO3:43 pmSan Francisco
Dec 1
SFO6:00 amSan Francisco
7h 26m
1 stop
ROA4:26 pmRoanoke
$373
American Airlines
Oct 7
ROA4:49 pmRoanoke
8h 07m
1 stop
SFO9:56 pmSan Francisco
Oct 11
SFO6:00 amSan Francisco
7h 18m
1 stop
ROA4:18 pmRoanoke
$376
American Airlines
Oct 9
ROA4:49 pmRoanoke
10h 10m
1 stop
SFO11:59 pmSan Francisco
Oct 12
SFO11:59 pmSan Francisco
10h 49m
1 stop
ROA1:48 pmRoanoke
$379

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 2/6

3:25 pm-9:35 pm

1 stop9h 10m

San Francisco

Tue 2/16

11:45 pm-10:34 am

1 stop7h 49m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 9/12

4:46 pm-11:57 pm

1 stop10h 11m

San Francisco

Tue 9/15

2:00 pm-11:59 pm

1 stop6h 59m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Tue 9/22

6:20 am-10:52 am

1 stop7h 32m

San Francisco

Wed 9/30

6:00 am-5:17 pm

1 stop8h 17m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 10/31

8:15 am-3:43 pm

1 stop10h 28m

San Francisco

Tue 12/1

6:00 am-4:26 pm

1 stop7h 26m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Tue 11/3

10:30 am-5:25 pm

1 stop9h 55m

San Francisco

Sat 11/7

11:30 pm-9:29 am

1 stop6h 59m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Wed 2/3

5:10 pm-10:14 pm

1 stop8h 04m

San Francisco

Tue 2/9

9:00 am-9:15 pm

1 stop9h 15m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Tue 2/9

6:00 am-11:59 am

1 stop8h 59m

San Francisco

Tue 2/16

2:00 pm-12:23 am

1 stop7h 23m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 2/6

3:25 pm-9:35 pm

1 stop9h 10m

San Francisco

Wed 2/10

9:30 pm-10:34 am

1 stop10h 04m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Mon 2/8

3:00 pm-8:49 pm

1 stop8h 49m

San Francisco

Sat 2/13

11:30 pm-10:11 am

1 stop7h 41m

$376
Quickest round-trip

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 9/12

8:05 pm-12:59 am

1 stop7h 54m

San Francisco

Sun 9/27

11:30 pm-9:57 am

1 stop7h 27m

$376

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Roanoke and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $418 to $553.
The lowest price recently found on this route was $373.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $390.

How far in advance should I book a flight from Roanoke to San Francisco?

You are more likely to see cheaper flights to San Francisco from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $477 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Roanoke for as low as $330 on momondo.

When to book flights from Roanoke to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to San Francisco (ROA to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Francisco

Fastest flight time

7h 21m

Direct flights

None
The fastest flight from Roanoke to San Francisco takes 7h 21m
There are no direct flights from Roanoke to San Francisco. There are no popular flight routes from Roanoke to San Francisco.
Search flight deals

Frequently asked questions about flying from Roanoke to San Francisco

  • How far is Roanoke to San Francisco by plane?

    A flight from Roanoke to San Francisco will travel around 2304.9 mi. Typically, this will take 7h 21m by plane in normal conditions.

  • When did momondo last update prices for flights from Roanoke Airport to San Francisco Airport?

    Prices for flights from Roanoke Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to San Francisco Airport?

  • How old do you have to be to fly from Roanoke Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to San Francisco?

Best airlines flying from Roanoke to San Francisco

Compare and see reviews for airlines that fly from Roanoke to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $308Free CancellationRating
7.4
10,108 reviews
Search United Airlines flights
DeltaPriceFrom $308Free CancellationRating
7.8
8,502 reviews
Search Delta flights
American AirlinesPriceFrom $309Free CancellationRating
7.1
11,929 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Fremont
Berkeley
Bodega Bay
Hayward
Walnut Creek
Santa Clara
Vallejo
Roseville
Sonoma
Salinas
Sunnyvale
Milpitas
Daly City
Burlingame
Marina
Palo Alto

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Roanoke with this policy.

How can momondo help me find flights from Roanoke to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Roanoke to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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