What is the cheapest airline that flies from Roanoke to San Francisco?

Delta is the most popular carrier operating from Roanoke to San Francisco

Which layover airport has the shortest connection time from Roanoke to San Francisco?

Chicago (ORD) has the shortest average layover time for this route: 1h 06m.

What airlines fly to San Francisco?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to San Francisco from Roanoke according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 3 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Roanoke and San Francisco?

Atlanta (ATL) was the most common stop: 43% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Roanoke to San Francisco?

Flights via Atlanta (ATL) offer the lowest average round-trip price of $434.

Which layover airport has the shortest travel time from Roanoke to San Francisco?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 8h 34m.

When did momondo last update prices for flights from Roanoke Airport to San Francisco Airport?

Prices for flights from Roanoke Airport to San Francisco Airport were last updated today.

How many operators does momondo search for flights from Roanoke Airport to San Francisco Airport?

As of August 2026, there are 3 operators available to choose from for flights from Roanoke Airport to San Francisco Airport.

How old do you have to be to fly from Roanoke Airport to San Francisco Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$230 Cheap Flights from Roanoke to San Francisco in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to San Francisco

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:46 pm - 11:57 pmROA Roanoke-SFO San Francisco

10h 11m1 stop Atlanta Hartsfield-Jackson

11:30 pm - 10:31 amSFO San Francisco-ROA Roanoke

8h 01m1 stop Atlanta Hartsfield-Jackson

$373Delta

Sat, Sep 19 - Tue, Sep 22

8:05 pm - 12:59 amROA Roanoke-SFO San Francisco

7h 54m1 stop Washington, D.C. Dulles Intl

5:00 am - 5:04 pmSFO San Francisco-ROA Roanoke

9h 04m1 stop Chicago O'Hare Intl

$373United Airlines

Sat, Sep 19 - Sat, Sep 26

8:15 am - 3:43 pmROA Roanoke-SFO San Francisco

10h 28m1 stop Charlotte Douglas

6:00 am - 4:26 pmSFO San Francisco-ROA Roanoke

7h 26m1 stop Chicago O'Hare Intl

$373American Airlines

Sat, Oct 31 - Tue, Dec 1

4:49 pm - 9:56 pmROA Roanoke-SFO San Francisco

8h 07m1 stop Chicago O'Hare Intl

9:50 pm - 9:43 amSFO San Francisco-ROA Roanoke

8h 53m1 stop Charlotte Douglas

$373American Airlines

Sat, Oct 31 - Tue, Dec 1

1:57 pm - 8:08 pmROA Roanoke-SFO San Francisco

9h 11m1 stop Charlotte Douglas

8:09 am - 8:59 pmSFO San Francisco-ROA Roanoke

9h 50m1 stop Charlotte Douglas

$373American Airlines

Tue, Sep 22 - Sat, Sep 26

6:15 am - 11:12 amROA Roanoke-SFO San Francisco

7h 57m1 stop Washington, D.C. Dulles Intl

10:35 pm - 9:57 amSFO San Francisco-ROA Roanoke

8h 22m1 stop Chicago O'Hare Intl

$376United Airlines

Sun, Sep 6 - Fri, Sep 25

4:46 pm - 9:51 pmROA Roanoke-SFO San Francisco

8h 05m1 stop Atlanta Hartsfield-Jackson

2:00 pm - 11:59 pmSFO San Francisco-ROA Roanoke

6h 59m1 stop Atlanta Hartsfield-Jackson

$376Delta

Fri, Sep 11 - Wed, Sep 16

4:46 pm - 11:57 pmROA Roanoke-SFO San Francisco

10h 11m1 stop Atlanta Hartsfield-Jackson

9:55 pm - 10:31 amSFO San Francisco-ROA Roanoke

9h 36m1 stop Atlanta Hartsfield-Jackson

$376Delta

Sat, Sep 19 - Mon, Sep 28

3:29 pm - 9:24 pmROA Roanoke-SFO San Francisco

8h 55m1 stop Atlanta Hartsfield-Jackson

9:30 pm - 10:34 amSFO San Francisco-ROA Roanoke

10h 04m1 stop Atlanta Hartsfield-Jackson

$376Delta

Wed, Dec 16 - Mon, Jan 18

5:51 pm - 12:30 amROA Roanoke-SFO San Francisco

9h 39m1 stop Chicago O'Hare Intl

11:30 pm - 9:57 amSFO San Francisco-ROA Roanoke

7h 27m1 stop Chicago O'Hare Intl

$400United Airlines

Fri, Oct 9 - Mon, Oct 12

Cheap last minute flights

Enter your travel dates to find the best prices.

10:44 am - 3:35 pmROA Roanoke-SFO San Francisco

7h 51m1 stop Chicago O'Hare Intl

11:30 pm - 9:59 amSFO San Francisco-ROA Roanoke

7h 29m1 stop Chicago O'Hare Intl

$416United Airlines

Tue, Aug 25 - Sat, Sep 19

6:40 am - 1:11 pmROA Roanoke-SFO San Francisco

9h 31m1 stop Chicago O'Hare Intl

6:00 am - 5:09 pmSFO San Francisco-ROA Roanoke

8h 09m1 stop Chicago O'Hare Intl

$416United Airlines

Tue, Aug 25 - Sat, Sep 19

2:23 pm - 7:56 pmROA Roanoke-SFO San Francisco

8h 33m1 stop Charlotte Douglas

7:40 am - 8:29 pmSFO San Francisco-ROA Roanoke

9h 49m1 stop Philadelphia

$419American Airlines

Tue, Aug 25 - Thu, Sep 17

8:05 pm - 12:59 amROA Roanoke-SFO San Francisco

7h 54m1 stop Washington, D.C. Dulles Intl

11:30 pm - 9:59 amSFO San Francisco-ROA Roanoke

7h 29m1 stop Chicago O'Hare Intl

$419United Airlines

Tue, Aug 25 - Fri, Sep 18

10:35 am - 7:05 pmROA Roanoke-SFO San Francisco

11h 30m2 stops Charlotte Douglas Dallas/Fort Worth

9:29 pm - 10:10 amSFO San Francisco-ROA Roanoke

9h 41m1 stop Philadelphia

$447American Airlines

Tue, Aug 25 - Sat, Sep 19

2:23 pm - 10:18 pmROA Roanoke-SFO San Francisco

10h 55m2 stops Charlotte Douglas Dallas/Fort Worth

11:58 pm - 1:51 pmSFO San Francisco-ROA Roanoke

10h 53m1 stop Philadelphia

$450American Airlines

Tue, Aug 25 - Fri, Sep 18

8:05 pm - 12:59 amROA Roanoke-SFO San Francisco

7h 54m1 stop Washington, D.C. Dulles Intl

10:55 pm - 8:54 pmSFO San Francisco-ROA Roanoke

18h 59m2 stops Sacramento Intl Chicago O'Hare Intl

$796United Airlines

Wed, Aug 26 - Fri, Aug 28

6:00 am - 4:56 pmROA Roanoke-SFO San Francisco

13h 56m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl

6:12 pm - 10:31 amSFO San Francisco-ROA Roanoke

13h 19m2 stops Los Angeles Atlanta Hartsfield-Jackson

$1,282Delta

Tue, Aug 25 - Sat, Sep 19

6:00 am - 4:56 pmROA Roanoke-SFO San Francisco

13h 56m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl

6:12 pm - 10:31 amSFO San Francisco-ROA Roanoke

13h 19m2 stops Los Angeles Atlanta Hartsfield-Jackson

$1,313Delta

Tue, Aug 25 - Sat, Sep 19

6:00 am - 1:31 pmROA Roanoke-SFO San Francisco

10h 31m2 stops Atlanta Hartsfield-Jackson Los Angeles

6:25 pm - 10:37 amSFO San Francisco-ROA Roanoke

13h 12m2 stops Los Angeles Atlanta Hartsfield-Jackson

$1,477Delta

Wed, Aug 26 - Fri, Aug 28

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United Airlines flights from Roanoke to San Francisco

Our best United Airlines deals on Roanoke to San Francisco flight tickets

United Airlines

Oct 9

ROA5:51 pmRoanoke

9h 39m

1 stop

SFO12:30 amSan Francisco

Oct 12

SFO11:30 pmSan Francisco

7h 27m

1 stop

ROA9:57 amRoanoke

$400

United Airlines

Aug 25

ROA6:40 amRoanoke

9h 31m

1 stop

SFO1:11 pmSan Francisco

Sep 19

SFO6:00 amSan Francisco

8h 09m

1 stop

ROA5:09 pmRoanoke

$416

United Airlines

Aug 25

ROA8:05 pmRoanoke

7h 54m

1 stop

SFO12:59 amSan Francisco

Sep 18

SFO11:30 pmSan Francisco

7h 29m

1 stop

ROA9:59 amRoanoke

$419

American Airlines flights from Roanoke to San Francisco

Our best American Airlines deals on Roanoke to San Francisco flight tickets

American Airlines

Oct 31

ROA8:15 amRoanoke

10h 28m

1 stop

SFO3:43 pmSan Francisco

Dec 1

SFO6:00 amSan Francisco

7h 26m

1 stop

ROA4:26 pmRoanoke

$373

American Airlines

Sep 9

ROA5:47 pmRoanoke

9h 11m

1 stop

SFO11:58 pmSan Francisco

Sep 13

SFO5:22 amSan Francisco

9h 25m

1 stop

ROA5:47 pmRoanoke

$376

American Airlines

Sep 4

ROA5:03 pmRoanoke

8h 37m

1 stop

SFO10:40 pmSan Francisco

Sep 11

SFO11:03 pmSan Francisco

7h 38m

1 stop

ROA9:41 amRoanoke

$419

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 9/19

4:46 pm-11:57 pm

1 stop10h 11m

San Francisco

Tue 9/22

11:30 pm-10:31 am

1 stop8h 01m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 9/19

8:05 pm-12:59 am

1 stop7h 54m

San Francisco

Sat 9/26

5:00 am-5:04 pm

1 stop9h 04m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 10/31

8:15 am-3:43 pm

1 stop10h 28m

San Francisco

Tue 12/1

6:00 am-4:26 pm

1 stop7h 26m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 10/31

4:49 pm-9:56 pm

1 stop8h 07m

San Francisco

Tue 12/1

9:50 pm-9:43 am

1 stop8h 53m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Tue 9/22

1:57 pm-8:08 pm

1 stop9h 11m

San Francisco

Sat 9/26

8:09 am-8:59 pm

1 stop9h 50m

$373

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sun 9/6

6:15 am-11:12 am

1 stop7h 57m

San Francisco

Fri 9/25

10:35 pm-9:57 am

1 stop8h 22m

$376

Quickest round-trip

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Fri 9/11

4:46 pm-9:51 pm

1 stop8h 05m

San Francisco

Wed 9/16

2:00 pm-11:59 pm

1 stop6h 59m

$376

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Sat 9/19

4:46 pm-11:57 pm

1 stop10h 11m

San Francisco

Mon 9/28

9:55 pm-10:31 am

1 stop9h 36m

$376

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Wed 12/16

3:29 pm-9:24 pm

1 stop8h 55m

San Francisco

Mon 1/18

9:30 pm-10:34 am

1 stop10h 04m

$376

RoanokeSan Francisco

ROA Roanoke - SFO San Francisco

ROASFO

Roanoke

Fri 10/9

5:51 pm-12:30 am

1 stop9h 39m

San Francisco

Mon 10/12

11:30 pm-9:57 am

1 stop7h 27m

$400

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Roanoke and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $430 to $573.
The lowest price recently found on this route was $373.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $390.

How far in advance should I book a flight from Roanoke to San Francisco?

You are more likely to see cheaper flights to San Francisco from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $474 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Roanoke for as low as $330 on momondo.

When to book flights from Roanoke to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Roanoke to San Francisco (ROA to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Francisco

Best Price Found	$230
Fastest flight time	7h 17m
Direct flights	None

The best one-way flight to San Francisco from Roanoke in the past 72 hours is $230. The best round-trip flight deal from Roanoke to San Francisco found on momondo in the last 72 hours is $373.

The fastest flight from Roanoke to San Francisco takes 7h 17m

There are no direct flights from Roanoke to San Francisco. There are no popular flight routes from Roanoke to San Francisco.

Search flight deals

Frequently asked questions about flying from Roanoke to San Francisco

How far is Roanoke to San Francisco by plane?
A flight from Roanoke to San Francisco will travel around 2304.9 mi. Typically, this will take 7h 17m by plane in normal conditions.
When did momondo last update prices for flights from Roanoke Airport to San Francisco Airport?
Prices for flights from Roanoke Airport to San Francisco Airport were last updated today.
How many operators does momondo search for flights from Roanoke Airport to San Francisco Airport?
As of August 2026, there are 3 operators available to choose from for flights from Roanoke Airport to San Francisco Airport.
How old do you have to be to fly from Roanoke Airport to San Francisco Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Roanoke to San Francisco?
momondo data reveals that the most frequently booked airline on the route from Roanoke to San Francisco is American Airlines, representing 53% of all bookings. The subsequent popular airlines are United Airlines at 39% and Delta at 8%.

Best airlines flying from Roanoke to San Francisco

Compare and see reviews for airlines that fly from Roanoke to San Francisco with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $308	Free Cancellation	Rating 7.4 10,105 reviews	Search United Airlines flights
Delta	PriceFrom $308	Free Cancellation	Rating 7.8 8,513 reviews	Search Delta flights
American Airlines	PriceFrom $309	Free Cancellation	Rating 7.1 11,979 reviews	Search American Airlines flights

Santa Cruz

Carmel-by-the-Sea

Modesto

South San Francisco

Fremont

Berkeley

Bodega Bay

Hayward

Walnut Creek

Santa Clara

Vallejo

Roseville

Sonoma

Salinas

Sunnyvale

Milpitas

Daly City

Marina

Palo Alto

Burlingame

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Roanoke with this policy.

How can momondo help me find flights from Roanoke to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Roanoke to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Roanoke to San Francisco from $230

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Francisco departing on 10/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Roanoke to San Francisco

Our best United Airlines deals on Roanoke to San Francisco flight tickets

American Airlines flights from Roanoke to San Francisco

Our best American Airlines deals on Roanoke to San Francisco flight tickets

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How to get the cheapest flight ticket from Roanoke to San Francisco

What is the typical price of a round-trip flight between Roanoke and San Francisco?

What is the cheapest month to fly to San Francisco?

How far in advance should I book a flight from Roanoke to San Francisco?

What is the cheapest airline that flies from Roanoke to San Francisco?

What airlines fly to San Francisco?

Which airport is the most popular layover for flights between Roanoke and San Francisco?

Which layover airport offers the lowest fares from Roanoke to San Francisco?

Which layover airport has the shortest travel time from Roanoke to San Francisco?

Which layover airport has the shortest connection time from Roanoke to San Francisco?

When to book flights from Roanoke to San Francisco

Cheap Roanoke to San Francisco (ROA to SFO) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Roanoke to San Francisco

Best airlines flying from Roanoke to San Francisco

Compare and see reviews for airlines that fly from Roanoke to San Francisco with momondo

Traveling to a place near San Francisco?

Why use momondo?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California

Fly your favorite airline to San Francisco

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Francisco

List of cabin classes available on flights landing in San Francisco. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

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