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Cheap flights from Portland, Maine to San Diego from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to San Diego departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Portland, Maine to San Diego (PWM-SAN)

Cheap round-trip flights

Delta Logo
6:30 am - 12:19 pmPWM-SAN
8h 49m1 stop
Delta Logo
12:35 pm - 11:49 pmSAN-PWM
8h 14m1 stop
$297Delta
Find Deal
Tue, Feb 24 - Tue, Mar 3
Delta Logo
6:30 am - 6:56 pmPWM-SAN
15h 26m2 stops
Delta Logo
12:35 pm - 11:49 pmSAN-PWM
8h 14m1 stop
$302Delta
Find Deal
Tue, Feb 24 - Tue, Mar 3
Delta Logo
2:35 pm - 10:00 pmPWM-SAN
10h 25m2 stops
Delta Logo
10:00 am - 11:49 pmSAN-PWM
10h 49m2 stops
$307Delta
Find Deal
Tue, Feb 24 - Wed, Mar 4
Southwest Logo
3:30 pm - 9:35 pmPWM-SAN
9h 05m1 stop
Southwest Logo
10:50 am - 12:05 amSAN-PWM
10h 15m1 stop
$336Southwest
Find Deal
Wed, Nov 19 - Wed, Nov 26
JetBlue Logo
7:09 am - 7:30 pmPWM-SAN
15h 21m1 stop
JetBlue Logo
10:06 am - 10:59 pmSAN-PWM
9h 53m1 stop
$339JetBlue
Find Deal
Tue, Oct 21 - Sat, Oct 25
Southwest Logo
12:45 pm - 8:50 pmPWM-SAN
11h 05m2 stops
Southwest Logo
10:50 am - 12:05 amSAN-PWM
10h 15m1 stop
$341Southwest
Find Deal
Wed, Nov 19 - Wed, Nov 26
United Airlines Logo
9:59 am - 3:01 pmPWM-SAN
8h 02m1 stop
United Airlines Logo
12:35 pm - 11:59 pmSAN-PWM
8h 24m1 stop
$348United Airlines
Find Deal
Tue, Sep 30 - Fri, Oct 3
United Airlines Logo
6:00 am - 12:27 pmPWM-SAN
9h 27m1 stop
United Airlines Logo
11:08 am - 11:59 pmSAN-PWM
9h 51m2 stops
$353United Airlines
Find Deal
Tue, Sep 30 - Fri, Oct 3
American Airlines Logo
9:18 am - 2:30 pmPWM-SAN
8h 12m1 stop
American Airlines Logo
10:45 pm - 11:14 amSAN-PWM
9h 29m1 stop
$368American Airlines
Find Deal
Sat, Oct 4 - Tue, Oct 7
American Airlines Logo
9:18 am - 3:53 pmPWM-SAN
9h 35m1 stop
American Airlines Logo
7:15 am - 8:14 pmSAN-PWM
9h 59m2 stops
$373American Airlines
Find Deal
Sat, Oct 4 - Tue, Oct 7

American Airlines flights from Portland, Maine to San Diego

Our best American Airlines deals on Portland, Maine to San Diego flight tickets
American Airlines
Oct 4
PWM9:18 amPortland
8h 12m
1 stop
SAN2:30 pmSan Diego
Oct 7
SAN10:45 pmSan Diego
9h 29m
1 stop
PWM11:14 amPortland
$368
Find similar
American Airlines
Oct 4
PWM9:18 amPortland
9h 35m
1 stop
SAN3:53 pmSan Diego
Oct 7
SAN7:15 amSan Diego
9h 59m
2 stops
PWM8:14 pmPortland
$373
Find similar
American Airlines
Oct 4
PWM9:18 amPortland
8h 12m
1 stop
SAN2:30 pmSan Diego
Oct 7
SAN6:15 amSan Diego
8h 58m
1 stop
PWM6:13 pmPortland
$377
Find similar

JetBlue flights from Portland, Maine to San Diego

Our best JetBlue deals on Portland, Maine to San Diego flight tickets
JetBlue
Oct 21
PWM7:09 amPortland
15h 21m
1 stop
SAN7:30 pmSan Diego
Oct 25
SAN10:06 amSan Diego
9h 53m
1 stop
PWM10:59 pmPortland
$339
Find similar
JetBlue
Sep 19
PWM7:09 amPortland
15h 21m
1 stop
SAN7:30 pmSan Diego
Sep 22
SAN8:40 pmSan Diego
13h 41m
1 stop
PWM1:21 pmPortland
$553
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 8, 2025.
Use the filters below to find and compare flights from Portland, Maine to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Tue 2/24

6:30 am-12:19 pm

1 stop8h 49m

San Diego

Tue 3/3

12:35 pm-11:49 pm

1 stop8h 14m

$297

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Tue 2/24

6:30 am-6:56 pm

2 stops15h 26m

San Diego

Tue 3/3

12:35 pm-11:49 pm

1 stop8h 14m

$302

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Tue 2/24

2:35 pm-10:00 pm

2 stops10h 25m

San Diego

Wed 3/4

10:00 am-11:49 pm

2 stops10h 49m

$307

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Wed 11/19

3:30 pm-9:35 pm

1 stop9h 05m

San Diego

Wed 11/26

10:50 am-12:05 am

1 stop10h 15m

$336

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Tue 10/21

7:09 am-7:30 pm

1 stop15h 21m

San Diego

Sat 10/25

10:06 am-10:59 pm

1 stop9h 53m

$339

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Wed 11/19

12:45 pm-8:50 pm

2 stops11h 05m

San Diego

Wed 11/26

10:50 am-12:05 am

1 stop10h 15m

$341

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Tue 9/30

9:59 am-3:01 pm

1 stop8h 02m

San Diego

Fri 10/3

12:35 pm-11:59 pm

1 stop8h 24m

$348

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Tue 9/30

6:00 am-12:27 pm

1 stop9h 27m

San Diego

Fri 10/3

11:08 am-11:59 pm

2 stops9h 51m

$353

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Sat 10/4

9:18 am-2:30 pm

1 stop8h 12m

San Diego

Tue 10/7

10:45 pm-11:14 am

1 stop9h 29m

$368

PortlandSan Diego

PWM - SAN

PWMSAN

Portland

Sat 10/4

9:18 am-3:53 pm

1 stop9h 35m

San Diego

Tue 10/7

7:15 am-8:14 pm

2 stops9h 59m

$373

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Portland, Maine to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from Portland, Maine during the month September is also very affordable. Most momondo users find prices during this month for around $407.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Portland, Maine to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $472. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $809. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $476. Flights in the morning are often more expensive with an average ticket price of $543.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Portland, Maine when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $497 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Portland, Maine for as low as $368 on momondo.

How have Portland, Maine to San Diego flight prices changed over time?

As of September 2025, prices for Portland, Maine to San Diego flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from Portland, Maine to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to San Diego (PWM to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to San Diego

Direct flights

None
There are no direct flights from Portland, Maine to San Diego. There are no popular flight routes from Portland, Maine to San Diego.
Search flight deals

  • How far is Portland to San Diego by plane?

    The distance between Portland and San Diego is about 2617.3 mi. In terms of flight time, this usually takes a little over 8h 02m.

  • When did momondo last update prices for flights from Portland Airport to San Diego Airport?

    Prices for flights from Portland Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to San Diego Airport?

  • How old do you have to be to fly from Portland Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Portland, Maine to San Diego?

Best airlines flying from Portland, Maine to San Diego

Compare and see reviews for airlines that fly from Portland, Maine to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $312Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $325Free CancellationRating
8.0
4,244 reviews
Search Southwest flights
DeltaPriceFrom $331Free CancellationRating
7.9
7,966 reviews
Search Delta flights
United AirlinesPriceFrom $375Free CancellationRating
7.4
8,944 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Imperial Beach
Poway
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Portland to San Diego?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to San Diego. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Portland with this policy.

How can momondo help me find flights from Portland to San Diego?

Once all potential Portland to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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