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Cheap flights from Mississippi to San Diego from $54

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to San Diego departing on 11/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:00 pm - 12:01 amMEM-SAN
30h 01m1 stop
Frontier Logo
6:25 am - 7:05 pmSAN-MEM
10h 40m1 stop
$192Frontier
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
9:16 pm - 4:12 pmMEM-SAN
44h 56m2 stops
Multiple Airlines Logo
2:28 pm - 7:05 pmSAN-MEM
26h 37m1 stop
$205Multiple Airlines
Find Deal
Tue, Dec 2 - Wed, Dec 10
Multiple Airlines Logo
9:17 pm - 9:57 amMEM-SAN
14h 40m2 stops
Multiple Airlines Logo
6:25 am - 7:05 pmSAN-MEM
10h 40m1 stop
$210Multiple Airlines
Find Deal
Fri, Dec 12 - Mon, Dec 15
Frontier Logo
8:12 pm - 10:25 pmMEM-SAN
28h 13m1 stop
Frontier Logo
7:30 pm - 7:15 pmSAN-MEM
21h 45m1 stop
$218Frontier
Find Deal
Fri, Oct 24 - Sat, Nov 8
United Airlines Logo
4:15 pm - 8:38 pmMEM-SAN
6h 23m1 stop
United Airlines Logo
1:55 pm - 9:59 pmSAN-MEM
6h 04m1 stop
$279United Airlines
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Sat, Feb 14 - Tue, Feb 17
Delta Logo
3:40 pm - 11:14 pmBTR-SAN
9h 34m1 stop
Delta Logo
6:15 am - 2:55 pmSAN-BTR
6h 40m1 stop
$289Delta
Find Deal
Fri, Oct 31 - Mon, Nov 3
Delta Logo
9:13 am - 4:08 pmMOB-SAN
8h 55m1 stop
Delta Logo
9:50 pm - 8:36 amSAN-MOB
8h 46m1 stop
$289Delta
Find Deal
Sat, Nov 8 - Mon, Nov 10
American Airlines Logo
5:25 am - 11:12 amGPT-SAN
7h 47m1 stop
American Airlines Logo
12:12 pm - 9:36 pmSAN-GPT
7h 24m1 stop
$289American Airlines
Find Deal
Wed, Feb 18 - Sat, Feb 21
United Airlines Logo
9:30 am - 5:29 pmBTR-SAN
9h 59m2 stops
United Airlines Logo
10:20 am - 5:28 pmSAN-BTR
5h 08m1 stop
$294United Airlines
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Fri, Oct 31 - Mon, Nov 3
American Airlines Logo
1:07 pm - 9:58 pmGPT-SAN
10h 51m2 stops
American Airlines Logo
6:15 am - 5:56 pmSAN-GPT
9h 41m2 stops
$299American Airlines
Find Deal
Thu, Jan 8 - Sun, Jan 11

Frontier flights from Mississippi to San Diego

Our best Frontier deals on Mississippi to San Diego flight tickets
Frontier
Dec 4
MEM8:00 pmMemphis
30h 01m
1 stop
SAN12:01 amSan Diego
Dec 7
SAN6:25 amSan Diego
10h 40m
1 stop
MEM7:05 pmMemphis
$192
Find similar
Frontier
Oct 24
MEM8:12 pmMemphis
28h 13m
1 stop
SAN10:25 pmSan Diego
Nov 8
SAN7:30 pmSan Diego
21h 45m
1 stop
MEM7:15 pmMemphis
$218
Find similar
Frontier
Dec 1
MEM7:59 pmMemphis
6h 00m
1 stop
SAN11:59 pmSan Diego
Dec 10
SAN2:28 pmSan Diego
26h 37m
1 stop
MEM7:05 pmMemphis
$220
Find similar

American Airlines flights from Mississippi to San Diego

Our best American Airlines deals on Mississippi to San Diego flight tickets
American Airlines
Feb 18
GPT5:25 amGulfport Biloxi Regional
7h 47m
1 stop
SAN11:12 amSan Diego
Feb 21
SAN12:12 pmSan Diego
7h 24m
1 stop
GPT9:36 pmGulfport Biloxi Regional
$289
Find similar
American Airlines
Jan 8
GPT1:07 pmGulfport Biloxi Regional
10h 51m
2 stops
SAN9:58 pmSan Diego
Jan 11
SAN6:15 amSan Diego
9h 41m
2 stops
GPT5:56 pmGulfport Biloxi Regional
$299
Find similar
American Airlines
Nov 8
GPT12:10 pmGulfport Biloxi Regional
7h 55m
1 stop
SAN6:05 pmSan Diego
Nov 15
SAN10:09 amSan Diego
10h 59m
2 stops
GPT11:08 pmGulfport Biloxi Regional
$314
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 9, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 12/4

8:00 pm-12:01 am

1 stop30h 01m

San Diego

Sun 12/7

6:25 am-7:05 pm

1 stop10h 40m

$192

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Tue 12/2

9:16 pm-4:12 pm

2 stops44h 56m

San Diego

Wed 12/10

2:28 pm-7:05 pm

1 stop26h 37m

$205

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Fri 12/12

9:17 pm-9:57 am

2 stops14h 40m

San Diego

Mon 12/15

6:25 am-7:05 pm

1 stop10h 40m

$210

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Fri 10/24

8:12 pm-10:25 pm

1 stop28h 13m

San Diego

Sat 11/8

7:30 pm-7:15 pm

1 stop21h 45m

$218

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Sat 2/14

4:15 pm-8:38 pm

1 stop6h 23m

San Diego

Tue 2/17

1:55 pm-9:59 pm

1 stop6h 04m

$279

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 10/31

3:40 pm-11:14 pm

1 stop9h 34m

San Diego

Mon 11/3

6:15 am-2:55 pm

1 stop6h 40m

$289

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Sat 11/8

9:13 am-4:08 pm

1 stop8h 55m

San Diego

Mon 11/10

9:50 pm-8:36 am

1 stop8h 46m

$289

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Wed 2/18

5:25 am-11:12 am

1 stop7h 47m

San Diego

Sat 2/21

12:12 pm-9:36 pm

1 stop7h 24m

$289

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 10/31

9:30 am-5:29 pm

2 stops9h 59m

San Diego

Mon 11/3

10:20 am-5:28 pm

1 stop5h 08m

$294

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 1/8

1:07 pm-9:58 pm

2 stops10h 51m

San Diego

Sun 1/11

6:15 am-5:56 pm

2 stops9h 41m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Mississippi to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of August, then departing from Mississippi during the month February is also very affordable. Most momondo users find prices during this month for around $379.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Mississippi to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $421. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $625. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $466. Flights in the evening are often more expensive with an average ticket price of $496.

Cheap Mississippi to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to San Diego

Direct flights

None
There are no direct flights from Mississippi to San Diego. There are no popular flight routes from Mississippi to San Diego.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to San Diego Airport?

    Prices for flights from Mississippi to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to San Diego Airport?

  • How old do you have to be to fly from Mississippi to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The travel and health documents you'll need for your trip to San Diego Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Diego Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Mississippi to San Diego

Compare and see reviews for airlines that fly from Mississippi to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $276Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.9
7,969 reviews
Search Delta flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
8,968 reviews
Search United Airlines flights
SouthwestPriceFrom $407Free CancellationRating
8.0
4,237 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
Poway
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to San Diego?

It is quick and easy to find Mississippi to San Diego flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Diego that suits you.

Can I find flights from Mississippi to San Diego with flexible booking policies on momondo?

Yes. All flights to San Diego from Mississippi on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Mississippi to San Diego?

Once all potential Mississippi to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Mississippi to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Mississippi to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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