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Cheap flights from Medford to San Luis Obispo from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to San Luis Obispo departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Medford to San Luis Obispo (MFR-SBP)

Cheap round-trip flights

Alaska Airlines Logo
4:08 pm - 10:41 pmMFR-SBP
6h 33m1 stop
Alaska Airlines Logo
7:50 pm - 11:16 amSBP-MFR
15h 26m1 stop
$294Alaska Airlines
Find Deal
Sat, Oct 4 - Mon, Oct 6
United Airlines Logo
6:00 am - 10:05 amMFR-SBP
4h 05m1 stop
United Airlines Logo
8:34 am - 12:07 pmSBP-MFR
3h 33m1 stop
$295United Airlines
Find Deal
Fri, Oct 3 - Mon, Oct 13
Alaska Airlines Logo
8:48 am - 11:26 pmMFR-SBP
14h 38m2 stops
Alaska Airlines Logo
7:56 pm - 11:30 amSBP-MFR
15h 34m1 stop
$314Alaska Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Alaska Airlines Logo
12:40 pm - 10:41 pmMFR-SBP
10h 01m2 stops
Alaska Airlines Logo
7:50 pm - 11:16 amSBP-MFR
15h 26m1 stop
$324Alaska Airlines
Find Deal
Sat, Oct 4 - Mon, Oct 6
Alaska Airlines Logo
8:48 am - 11:26 pmMFR-SBP
14h 38m2 stops
Alaska Airlines Logo
5:35 pm - 11:54 amSBP-MFR
18h 19m2 stops
$352Alaska Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Alaska Airlines Logo
5:47 pm - 1:32 pmMFR-SBP
19h 45m2 stops
Alaska Airlines Logo
2:14 pm - 2:01 pmSBP-MFR
23h 47m2 stops
$353Alaska Airlines
Find Deal
Thu, Oct 2 - Tue, Oct 7
Alaska Airlines Logo
4:10 pm - 4:17 pmMFR-SBP
24h 07m1 stop
Alaska Airlines Logo
2:19 pm - 11:16 amSBP-MFR
20h 57m2 stops
$361Alaska Airlines
Find Deal
Thu, Oct 2 - Tue, Oct 7
Hawaiian Airlines Logo
12:39 pm - 4:43 pmMFR-SBP
4h 04m1 stop
Hawaiian Airlines Logo
6:29 pm - 12:33 amSBP-MFR
6h 04m1 stop
$404Hawaiian Airlines
Find Deal
Fri, Sep 19 - Fri, Sep 26
United Airlines Logo
6:00 am - 12:16 pmMFR-SBP
6h 16m1 stop
United Airlines Logo
4:00 pm - 12:07 pmSBP-MFR
20h 07m2 stops
$415United Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5
American Airlines Logo
5:30 am - 12:03 pmMFR-SBP
6h 33m1 stop
American Airlines Logo
6:00 am - 1:28 pmSBP-MFR
7h 28m1 stop
$481American Airlines
Find Deal
Mon, Sep 15 - Tue, Sep 16

United Airlines flights from Medford to San Luis Obispo

Our best United Airlines deals on Medford to San Luis Obispo flight tickets
United Airlines
Oct 3
MFR6:00 amMedford
4h 05m
1 stop
SBP10:05 amSan Luis Obispo County
Oct 13
SBP8:34 amSan Luis Obispo County
3h 33m
1 stop
MFR12:07 pmMedford
$295
Find similar
United Airlines
Oct 3
MFR6:00 amMedford
6h 16m
1 stop
SBP12:16 pmSan Luis Obispo County
Oct 5
SBP4:00 pmSan Luis Obispo County
20h 07m
2 stops
MFR12:07 pmMedford
$415
Find similar
United Airlines
Oct 9
MFR6:00 amMedford
4h 05m
1 stop
SBP10:05 amSan Luis Obispo County
Oct 13
SBP4:00 pmSan Luis Obispo County
20h 07m
2 stops
MFR12:07 pmMedford
$446
Find similar

Alaska Airlines flights from Medford to San Luis Obispo

Our best Alaska Airlines deals on Medford to San Luis Obispo flight tickets
Alaska Airlines
Oct 4
MFR4:08 pmMedford
6h 33m
1 stop
SBP10:41 pmSan Luis Obispo County
Oct 6
SBP7:50 pmSan Luis Obispo County
15h 26m
1 stop
MFR11:16 amMedford
$294
Find similar
Alaska Airlines
Nov 14
MFR8:48 amMedford
14h 38m
2 stops
SBP11:26 pmSan Luis Obispo County
Nov 17
SBP7:56 pmSan Luis Obispo County
15h 34m
1 stop
MFR11:30 amMedford
$314
Find similar
Alaska Airlines
Oct 4
MFR12:40 pmMedford
10h 01m
2 stops
SBP10:41 pmSan Luis Obispo County
Oct 6
SBP7:50 pmSan Luis Obispo County
15h 26m
1 stop
MFR11:16 amMedford
$324
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medford to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Medford to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 10/4

4:08 pm-10:41 pm

1 stop6h 33m

San Luis Obispo County

Mon 10/6

7:50 pm-11:16 am

1 stop15h 26m

$294

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 10/3

6:00 am-10:05 am

1 stop4h 05m

San Luis Obispo County

Mon 10/13

8:34 am-12:07 pm

1 stop3h 33m

$295

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 11/14

8:48 am-11:26 pm

2 stops14h 38m

San Luis Obispo County

Mon 11/17

7:56 pm-11:30 am

1 stop15h 34m

$314

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 10/4

12:40 pm-10:41 pm

2 stops10h 01m

San Luis Obispo County

Mon 10/6

7:50 pm-11:16 am

1 stop15h 26m

$324

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 11/14

8:48 am-11:26 pm

2 stops14h 38m

San Luis Obispo County

Mon 11/17

5:35 pm-11:54 am

2 stops18h 19m

$352

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Thu 10/2

5:47 pm-1:32 pm

2 stops19h 45m

San Luis Obispo County

Tue 10/7

2:14 pm-2:01 pm

2 stops23h 47m

$353

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Thu 10/2

4:10 pm-4:17 pm

1 stop24h 07m

San Luis Obispo County

Tue 10/7

2:19 pm-11:16 am

2 stops20h 57m

$361

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 9/19

12:39 pm-4:43 pm

1 stop4h 04m

San Luis Obispo County

Fri 9/26

6:29 pm-12:33 am

1 stop6h 04m

$404

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 10/3

6:00 am-12:16 pm

1 stop6h 16m

San Luis Obispo County

Sun 10/5

4:00 pm-12:07 pm

2 stops20h 07m

$415

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 9/15

5:30 am-12:03 pm

1 stop6h 33m

San Luis Obispo County

Tue 9/16

6:00 am-1:28 pm

1 stop7h 28m

$481

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Medford to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medford and San Luis Obispo?

What is the cheapest month to fly to San Luis Obispo?

In general, May is the cheapest month to fly from Medford to San Luis Obispo. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $290. The month of January is another great option to travel to San Luis Obispo, with average flight prices from Medford averaging around $300.

What is the cheapest day to depart on your flight to San Luis Obispo?

On average, the least expensive day to fly to San Luis Obispo from Medford is on a Friday. momondo users have found tickets for Friday departures for as low as $382. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Medford to San Luis Obispo for around $497.

What is the cheapest time of day to depart on your flight to San Luis Obispo?

Flying to San Luis Obispo from Medford at noon is the least expensive time of day to depart. momondo users have found prices as low as $412 when looking at flights departing at noon. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $468 on average. Flights to San Luis Obispo from Medford in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Medford to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to San Luis Obispo (MFR to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to San Luis Obispo

Direct flights

None
There are no direct flights from Medford to San Luis Obispo. There are no popular flight routes from Medford to San Luis Obispo.
Search flight deals

  • How far is Medford to San Luis Obispo County by plane?

    The distance between Medford and San Luis Obispo County is about 500.7 mi. Typically, this will take 3h 20m by plane in normal conditions.

  • When did momondo last update prices for flights from Medford Airport to San Luis Obispo County Airport?

    Prices for flights from Medford Airport to San Luis Obispo County Airport were last updated today.

  • How many operators does momondo search for flights from Medford Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Medford Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The travel and health documents required for your trip to San Luis Obispo County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Luis Obispo County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Medford to San Luis Obispo?

Best airlines flying from Medford to San Luis Obispo

Compare and see reviews for airlines that fly from Medford to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $286Free CancellationRating
7.4
8,939 reviews
Search United Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Cambria
Paso Robles
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Medford to San Luis Obispo?

Finding the right flight to San Luis Obispo from Medford is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Luis Obispo quick and easy, saving you time and money.

Can I find flights from Medford to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Medford to San Luis Obispo flights to just show those with flexible booking policies.

How can momondo help me find flights from Medford to San Luis Obispo?

Once all potential Medford to San Luis Obispo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to San Luis Obispo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Luis Obispo from Medford. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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