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Cheap flights from Medford to San Luis Obispo from $243

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to San Luis Obispo departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Medford to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Alaska Airlines Logo
1:10 pm - 11:17 pm
MFR
-
SBP
10h 07m
1 stop
Alaska Airlines Logo
6:00 am - 12:33 pm
SBP
-
MFR
6h 33m
1 stop
$243Alaska Airlines
Sat, Feb 28 - Wed, Mar 4
United Airlines Logo
2:00 pm - 11:59 pm
MFR
-
SBP
9h 59m
2 stops
United Airlines Logo
6:05 am - 10:56 am
SBP
-
MFR
4h 51m
1 stop
$272United Airlines
Sat, Feb 28 - Wed, Mar 4
Alaska Airlines Logo
5:45 am - 11:17 pm
MFR
-
SBP
17h 32m
2 stops
Alaska Airlines Logo
12:19 pm - 11:59 pm
SBP
-
MFR
11h 40m
2 stops
$343Alaska Airlines
Sat, Feb 28 - Wed, Mar 4
United Airlines Logo
6:25 pm - 11:59 pm
MFR
-
SBP
5h 34m
1 stop
United Airlines Logo
6:05 am - 10:56 am
SBP
-
MFR
4h 51m
1 stop
$492United Airlines
Mon, Feb 16 - Thu, Feb 19
Alaska Airlines Logo
3:38 pm - 4:54 pm
MFR
-
SBP
25h 16m
1 stop
Alaska Airlines Logo
6:00 am - 12:33 pm
SBP
-
MFR
6h 33m
1 stop
$496Alaska Airlines
Mon, Feb 16 - Thu, Feb 19
United Airlines Logo
2:00 pm - 11:59 pm
MFR
-
SBP
9h 59m
2 stops
United Airlines Logo
6:05 am - 10:56 am
SBP
-
MFR
4h 51m
1 stop
$497United Airlines
Mon, Feb 16 - Thu, Feb 19
United Airlines Logo
7:00 am - 5:15 pm
MFR
-
SBP
10h 15m
2 stops
United Airlines Logo
6:05 am - 10:56 am
SBP
-
MFR
4h 51m
1 stop
$505United Airlines
Mon, Feb 16 - Thu, Feb 19
Alaska Airlines Logo
5:08 am - 3:07 pm
MFR
-
SBP
9h 59m
2 stops
Alaska Airlines Logo
6:00 am - 10:57 pm
SBP
-
MFR
16h 57m
2 stops
$688Alaska Airlines
Mon, Feb 16 - Thu, Feb 19
Alaska Airlines Logo
5:08 am - 3:07 pm
MFR
-
SBP
9h 59m
2 stops
Alaska Airlines Logo
6:00 am - 10:57 pm
SBP
-
MFR
16h 57m
2 stops
$712Alaska Airlines
Mon, Feb 16 - Thu, Feb 19

Alaska Airlines flights from Medford to San Luis Obispo

Our best Alaska Airlines deals on Medford to San Luis Obispo flight tickets
Alaska Airlines
Feb 28
MFR1:10 pmMedford
10h 07m
1 stop
SBP11:17 pmSan Luis Obispo County
Mar 4
SBP6:00 amSan Luis Obispo County
6h 33m
1 stop
MFR12:33 pmMedford
$243
Alaska Airlines
Feb 28
MFR5:45 amMedford
17h 32m
2 stops
SBP11:17 pmSan Luis Obispo County
Mar 4
SBP12:19 pmSan Luis Obispo County
11h 40m
2 stops
MFR11:59 pmMedford
$343
Alaska Airlines
Feb 16
MFR3:38 pmMedford
25h 16m
1 stop
SBP4:54 pmSan Luis Obispo County
Feb 19
SBP6:00 amSan Luis Obispo County
6h 33m
1 stop
MFR12:33 pmMedford
$496

United Airlines flights from Medford to San Luis Obispo

Our best United Airlines deals on Medford to San Luis Obispo flight tickets
United Airlines
Feb 28
MFR2:00 pmMedford
9h 59m
2 stops
SBP11:59 pmSan Luis Obispo County
Mar 4
SBP6:05 amSan Luis Obispo County
4h 51m
1 stop
MFR10:56 amMedford
$272
United Airlines
Feb 16
MFR6:25 pmMedford
5h 34m
1 stop
SBP11:59 pmSan Luis Obispo County
Feb 19
SBP6:05 amSan Luis Obispo County
4h 51m
1 stop
MFR10:56 amMedford
$492
United Airlines
Feb 16
MFR2:00 pmMedford
9h 59m
2 stops
SBP11:59 pmSan Luis Obispo County
Feb 19
SBP6:05 amSan Luis Obispo County
4h 51m
1 stop
MFR10:56 amMedford
$497

momondo Fare Finder

 
Customize your flight search to find flights from Medford to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Medford to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 2/28

1:10 pm-11:17 pm

1 stop10h 07m

San Luis Obispo County

Wed 3/4

6:00 am-12:33 pm

1 stop6h 33m

$243

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 2/28

2:00 pm-11:59 pm

2 stops9h 59m

San Luis Obispo County

Wed 3/4

6:05 am-10:56 am

1 stop4h 51m

$272

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 2/28

5:45 am-11:17 pm

2 stops17h 32m

San Luis Obispo County

Wed 3/4

12:19 pm-11:59 pm

2 stops11h 40m

$343

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 2/16

6:25 pm-11:59 pm

1 stop5h 34m

San Luis Obispo County

Thu 2/19

6:05 am-10:56 am

1 stop4h 51m

$492

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 2/16

3:38 pm-4:54 pm

1 stop25h 16m

San Luis Obispo County

Thu 2/19

6:00 am-12:33 pm

1 stop6h 33m

$496

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 2/16

2:00 pm-11:59 pm

2 stops9h 59m

San Luis Obispo County

Thu 2/19

6:05 am-10:56 am

1 stop4h 51m

$497

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 2/16

7:00 am-5:15 pm

2 stops10h 15m

San Luis Obispo County

Thu 2/19

6:05 am-10:56 am

1 stop4h 51m

$505

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 2/16

5:08 am-3:07 pm

2 stops9h 59m

San Luis Obispo County

Thu 2/19

6:00 am-10:57 pm

2 stops16h 57m

$688

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Mon 2/16

5:08 am-3:07 pm

2 stops9h 59m

San Luis Obispo County

Thu 2/19

6:00 am-10:57 pm

2 stops16h 57m

$712

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Thu 2/12

5:13 am-12:03 pm

1 stop6h 50m

$273

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Medford to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Medford to San Luis Obispo County?

American Airlines and United Airlines are the most popular carriers operating from Medford to San Luis Obispo County

When to book flights from Medford to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to San Luis Obispo (MFR to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to San Luis Obispo

Fastest flight time

3h 46m

Direct flights

None
The fastest flight from Medford to San Luis Obispo takes 3h 46m
There are no direct flights from Medford to San Luis Obispo. There are no popular flight routes from Medford to San Luis Obispo.
Search flight deals

  • How far is Medford to San Luis Obispo County by plane?

    The distance between Medford and San Luis Obispo County is about 500.7 mi. Typically, this will take 3h 46m by plane in normal conditions.

  • When did momondo last update prices for flights from Medford Airport to San Luis Obispo County Airport?

    Prices for flights from Medford Airport to San Luis Obispo County Airport were last updated today.

  • How many operators does momondo search for flights from Medford Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Medford Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The travel and health documents required for your trip to San Luis Obispo County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Luis Obispo County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Medford to San Luis Obispo?

Best airlines flying from Medford to San Luis Obispo

Compare and see reviews for airlines that fly from Medford to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $211Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
Alaska AirlinesPriceFrom $242Free CancellationRating
8.0
11,807 reviews
Search Alaska Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Paso Robles
Cambria
Avila Beach
Cayucos
San Simeon
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Medford to San Luis Obispo?

Finding the right flight to San Luis Obispo from Medford is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Luis Obispo quick and easy, saving you time and money.

Can I find flights from Medford to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Medford to San Luis Obispo flights to just show those with flexible booking policies.

How can momondo help me find flights from Medford to San Luis Obispo?

Once all potential Medford to San Luis Obispo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to San Luis Obispo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Luis Obispo from Medford. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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