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Cheap flights from Medford to San Luis Obispo from $242

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to San Luis Obispo departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Medford to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Hawaiian Airlines Logo
11:45 am - 6:22 pmMFR-SBP
6h 37m1 stop
Hawaiian Airlines Logo
7:25 pm - 12:09 amSBP-MFR
4h 44m1 stop
$242Hawaiian Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
Alaska Airlines Logo
12:30 pm - 11:07 pmMFR-SBP
10h 37m1 stop
Alaska Airlines Logo
7:25 pm - 12:09 amSBP-MFR
4h 44m1 stop
$252Alaska Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
Alaska Airlines Logo
11:45 am - 6:22 pmMFR-SBP
6h 37m1 stop
Alaska Airlines Logo
6:00 am - 3:39 pmSBP-MFR
9h 39m2 stops
$287Alaska Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
Alaska Airlines Logo
5:05 am - 6:22 pmMFR-SBP
13h 17m2 stops
Alaska Airlines Logo
7:25 pm - 3:00 pmSBP-MFR
19h 35m1 stop
$291Alaska Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
Alaska Airlines Logo
5:05 am - 1:38 pmMFR-SBP
8h 33m2 stops
Alaska Airlines Logo
6:00 am - 3:39 pmSBP-MFR
9h 39m2 stops
$293Alaska Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
Alaska Airlines Logo
5:05 am - 1:38 pmMFR-SBP
8h 33m2 stops
Alaska Airlines Logo
6:00 am - 3:39 pmSBP-MFR
9h 39m2 stops
$313Alaska Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
Alaska Airlines Logo
1:25 pm - 11:35 pmMFR-SBP
10h 10m1 stop
Alaska Airlines Logo
7:45 pm - 3:10 pmSBP-MFR
19h 25m2 stops
$373Alaska Airlines
Find Deal
Fri, Dec 19 - Tue, Dec 23
Alaska Airlines Logo
12:39 pm - 11:35 pmMFR-SBP
10h 56m2 stops
Alaska Airlines Logo
7:45 pm - 3:10 pmSBP-MFR
19h 25m2 stops
$423Alaska Airlines
Find Deal
Fri, Dec 19 - Tue, Dec 23
Alaska Airlines Logo
5:00 am - 3:03 pmMFR-SBP
10h 03m1 stop
Alaska Airlines Logo
7:45 pm - 3:10 pmSBP-MFR
19h 25m2 stops
$429Alaska Airlines
Find Deal
Wed, Dec 24 - Sun, Dec 28
Alaska Airlines Logo
1:25 pm - 4:40 pmMFR-SBP
27h 15m1 stop
Alaska Airlines Logo
3:55 pm - 2:51 pmSBP-MFR
22h 56m1 stop
$452Alaska Airlines
Find Deal
Fri, Dec 19 - Tue, Dec 23

Alaska Airlines flights from Medford to San Luis Obispo

Our best Alaska Airlines deals on Medford to San Luis Obispo flight tickets
Alaska Airlines
Mar 7
MFR12:30 pmMedford
10h 37m
1 stop
SBP11:07 pmSan Luis Obispo County
Mar 10
SBP7:25 pmSan Luis Obispo County
4h 44m
1 stop
MFR12:09 amMedford
$252
Find similar
Alaska Airlines
Mar 7
MFR11:45 amMedford
6h 37m
1 stop
SBP6:22 pmSan Luis Obispo County
Mar 10
SBP6:00 amSan Luis Obispo County
9h 39m
2 stops
MFR3:39 pmMedford
$287
Find similar
Alaska Airlines
Mar 7
MFR5:05 amMedford
13h 17m
2 stops
SBP6:22 pmSan Luis Obispo County
Mar 10
SBP7:25 pmSan Luis Obispo County
19h 35m
1 stop
MFR3:00 pmMedford
$291
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medford to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Medford to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 3/7

11:45 am-6:22 pm

1 stop6h 37m

San Luis Obispo County

Tue 3/10

7:25 pm-12:09 am

1 stop4h 44m

$242

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 3/7

12:30 pm-11:07 pm

1 stop10h 37m

San Luis Obispo County

Tue 3/10

7:25 pm-12:09 am

1 stop4h 44m

$252

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 3/7

11:45 am-6:22 pm

1 stop6h 37m

San Luis Obispo County

Tue 3/10

6:00 am-3:39 pm

2 stops9h 39m

$287

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 3/7

5:05 am-6:22 pm

2 stops13h 17m

San Luis Obispo County

Tue 3/10

7:25 pm-3:00 pm

1 stop19h 35m

$291

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 3/7

5:05 am-1:38 pm

2 stops8h 33m

San Luis Obispo County

Tue 3/10

6:00 am-3:39 pm

2 stops9h 39m

$293

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Sat 3/7

5:05 am-1:38 pm

2 stops8h 33m

San Luis Obispo County

Tue 3/10

6:00 am-3:39 pm

2 stops9h 39m

$313

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 12/19

1:25 pm-11:35 pm

1 stop10h 10m

San Luis Obispo County

Tue 12/23

7:45 pm-3:10 pm

2 stops19h 25m

$373

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 12/19

12:39 pm-11:35 pm

2 stops10h 56m

San Luis Obispo County

Tue 12/23

7:45 pm-3:10 pm

2 stops19h 25m

$423

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Wed 12/24

5:00 am-3:03 pm

1 stop10h 03m

San Luis Obispo County

Sun 12/28

7:45 pm-3:10 pm

2 stops19h 25m

$429

MedfordSan Luis Obispo

MFR - SBP

MFRSBP

Medford

Fri 12/19

1:25 pm-4:40 pm

1 stop27h 15m

San Luis Obispo County

Tue 12/23

3:55 pm-2:51 pm

1 stop22h 56m

$452

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Medford to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medford and San Luis Obispo?

What is the cheapest month to fly to San Luis Obispo?

In general, May is the cheapest month to fly from Medford to San Luis Obispo. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $290. The month of January is another great option to travel to San Luis Obispo, with average flight prices from Medford averaging around $300.

What is the cheapest day to depart on your flight to San Luis Obispo?

On average, the least expensive day to fly to San Luis Obispo from Medford is on a Friday. momondo users have found tickets for Friday departures for as low as $382. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Medford to San Luis Obispo for around $497.

What is the cheapest time of day to depart on your flight to San Luis Obispo?

Flying to San Luis Obispo from Medford at noon is the least expensive time of day to depart. momondo users have found prices as low as $412 when looking at flights departing at noon. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $468 on average. Flights to San Luis Obispo from Medford in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Medford to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medford to San Luis Obispo (MFR to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to San Luis Obispo

Direct flights

None
There are no direct flights from Medford to San Luis Obispo. There are no popular flight routes from Medford to San Luis Obispo.
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  • How far is Medford to San Luis Obispo County by plane?

    The distance between Medford and San Luis Obispo County is about 500.7 mi. Typically, this will take 6h 37m by plane in normal conditions.

  • When did momondo last update prices for flights from Medford Airport to San Luis Obispo County Airport?

    Prices for flights from Medford Airport to San Luis Obispo County Airport were last updated today.

  • How many operators does momondo search for flights from Medford Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Medford Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The travel and health documents required for your trip to San Luis Obispo County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Luis Obispo County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Medford to San Luis Obispo?

Best airlines flying from Medford to San Luis Obispo

Compare and see reviews for airlines that fly from Medford to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $288Free CancellationRating
7.4
8,999 reviews
Search United Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Paso Robles
Cambria
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Medford to San Luis Obispo?

Finding the right flight to San Luis Obispo from Medford is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Luis Obispo quick and easy, saving you time and money.

Can I find flights from Medford to San Luis Obispo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Medford to San Luis Obispo flights to just show those with flexible booking policies.

How can momondo help me find flights from Medford to San Luis Obispo?

Once all potential Medford to San Luis Obispo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to San Luis Obispo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Luis Obispo from Medford. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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