Cheap flights from Massachusetts to San Francisco from $143

If you aren’t able to travel to San Francisco during the month of January, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $335.

The cheapest day to depart from Massachusetts to San Francisco is on a Wednesday when prices can be found for as low as $411. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $582.

Our data shows that the cheapest Massachusetts to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $363. Flights in the afternoon are often more expensive with an average ticket price of $504.

Fly from Boston Logan Intl to San Francisco for the best Massachusetts - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $404 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Massachusetts for as low as $336 on momondo.

There are 4 cabin classes available to choose from on Massachusetts to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

American Airlines, United Airlines, and Delta are the most popular carriers operating from Massachusetts to San Francisco

JetBlue, United Airlines and Delta are the top three most popular airlines that fly to San Francisco from Massachusetts according to our data. JetBlue is the first choice among our users, with 44% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 9 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

The number of flights available between Massachusetts and San Francisco is 46 per day as of June 2026. The most frequent departure time is 7:00AM, with 50% of daily flights leaving at noon.

The number of flights available between Massachusetts and San Francisco is 322 per week as of June 2026. The most frequent departure day is Fri, with 16% of weekly flights leaving on this day.