Cheap flights from Maine to San Francisco from $136

If you aren’t able to travel to San Francisco during the month of November, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $407.

The cheapest day to depart from Maine to San Francisco is on a Sunday when prices can be found for as low as $619. The most expensive day to fly to San Francisco is Saturday, with ticket prices averaging around $1,141.

Our data shows that the cheapest Maine to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $603. Flights in the afternoon are often more expensive with an average ticket price of $1,141.

Fly from Portland to San Francisco for the best Maine - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Maine when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $515 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Maine for as low as $318 on momondo.

There are 2 cabin classes available to choose from on Maine to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Delta, and United Airlines are the most popular carriers operating from Maine to San Francisco

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to San Francisco from Maine according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 5 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

The number of flights available between Maine and San Francisco is 192 per week as of September 2026. The most frequent departure day is Wed, with 22% of weekly flights leaving on this day.

Flight times from Maine to San Francisco vary, but if you’re flying out of Portland and flying into San Francisco (one of the most popular routes), then the duration is 6h 35m on average. Another popular route from Maine to San Francisco is flying from Bangor to San Francisco, which will take roughly 10h 47m. Keep in mind that layovers or delays could extend your travel time.