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Cheap flights from Louisville to San Francisco from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to San Francisco departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisville to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
10:45 am - 9:20 pm
SDF
-
SFO
13h 35m
1 stop
Southwest Logo
5:25 am - 3:05 pm
SFO
-
SDF
6h 40m
1 stop
$346Southwest
Sat, Apr 18 - Wed, Apr 22
Multiple Airlines Logo
7:48 pm - 5:34 pm
SDF
-
SFO
24h 46m
2 stops
Multiple Airlines Logo
8:48 pm - 7:26 pm
SFO
-
SDF
19h 38m
1 stop
$348Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
7:48 pm - 5:34 pm
SDF
-
SFO
24h 46m
2 stops
Multiple Airlines Logo
8:48 pm - 7:26 pm
SFO
-
SDF
19h 38m
1 stop
$349Multiple Airlines
Mon, Apr 27 - Tue, May 5
Southwest Logo
1:45 pm - 9:20 pm
SDF
-
SFO
10h 35m
2 stops
Southwest Logo
7:40 pm - 9:55 am
SFO
-
SDF
11h 15m
2 stops
$351Southwest
Sat, Apr 18 - Wed, Apr 22
Multiple Airlines Logo
7:48 pm - 8:36 pm
SDF
-
SFO
27h 48m
3 stops
Multiple Airlines Logo
12:18 pm - 7:48 pm
SFO
-
SDF
4h 30mnonstop
$357Multiple Airlines
Mon, May 11 - Mon, May 18
Multiple Airlines Logo
2:27 pm - 5:34 pm
SDF
-
SFO
30h 07m
2 stops
Multiple Airlines Logo
12:18 pm - 7:48 pm
SFO
-
SDF
4h 30mnonstop
$366Multiple Airlines
Thu, Apr 30 - Fri, May 8
Breeze Airways Logo
9:31 am - 11:33 am
SDF
-
SFO
5h 02mnonstop
Breeze Airways Logo
12:18 pm - 7:48 pm
SFO
-
SDF
4h 30mnonstop
$367Breeze Airways
Mon, May 18 - Mon, May 25
United Airlines Logo
5:00 am - 9:16 am
SDF
-
SFO
7h 16m
1 stop
United Airlines Logo
5:00 am - 2:41 pm
SFO
-
SDF
6h 41m
1 stop
$370United Airlines
Wed, Apr 22 - Tue, May 5
Multiple Airlines Logo
6:06 pm - 5:34 pm
SDF
-
SFO
26h 28m
2 stops
Multiple Airlines Logo
8:48 pm - 7:26 pm
SFO
-
SDF
19h 38m
1 stop
$372Multiple Airlines
Fri, May 1 - Tue, May 5
United Airlines Logo
6:00 pm - 8:09 pm
SDF
-
SFO
5h 09mnonstop
United Airlines Logo
10:35 pm - 6:16 am
SFO
-
SDF
4h 41mnonstop
$373United Airlines
Thu, Apr 30 - Sat, May 2

American Airlines flights from Louisville to San Francisco

Our best American Airlines deals on Louisville to San Francisco flight tickets
American Airlines
Apr 5
SDF10:49 amLouisville Intl
9h 27m
1 stop
SFO5:16 pmSan Francisco
Apr 12
SFO11:59 pmSan Francisco
7h 16m
1 stop
SDF10:15 amLouisville Intl
$565
American Airlines
Mar 28
SDF6:00 amLouisville Intl
12h 05m
1 stop
SFO3:05 pmSan Francisco
Mar 31
SFO5:56 pmSan Francisco
13h 08m
1 stop
SDF10:04 amLouisville Intl
$879
American Airlines
Apr 2
SDF6:23 pmLouisville Intl
9h 25m
1 stop
SFO12:48 amSan Francisco
Apr 10
SFO10:42 amSan Francisco
7h 48m
1 stop
SDF9:30 pmLouisville Intl
$880

Alaska Airlines flights from Louisville to San Francisco

Our best Alaska Airlines deals on Louisville to San Francisco flight tickets
Alaska Airlines
Apr 2
SDF6:33 amLouisville Intl
11h 04m
2 stops
SFO2:37 pmSan Francisco
Apr 5
SFO6:35 amSan Francisco
13h 03m
2 stops
SDF10:38 pmLouisville Intl
$807
Alaska Airlines
Apr 5
SDF6:12 pmLouisville Intl
18h 21m
2 stops
SFO9:33 amSan Francisco
Apr 12
SFO5:09 pmSan Francisco
22h 21m
2 stops
SDF6:30 pmLouisville Intl
$853
Alaska Airlines
Mar 23
SDF10:49 amLouisville Intl
13h 21m
2 stops
SFO9:10 pmSan Francisco
Apr 13
SFO7:31 pmSan Francisco
19h 59m
2 stops
SDF6:30 pmLouisville Intl
$887

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Louisville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Sat 4/18

10:45 am-9:20 pm

1 stop13h 35m

San Francisco

Wed 4/22

5:25 am-3:05 pm

1 stop6h 40m

$346

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Mon 4/27

7:48 pm-5:34 pm

2 stops24h 46m

San Francisco

Tue 5/5

8:48 pm-7:26 pm

1 stop19h 38m

$348

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Mon 4/27

7:48 pm-5:34 pm

2 stops24h 46m

San Francisco

Tue 5/5

8:48 pm-7:26 pm

1 stop19h 38m

$349

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Sat 4/18

1:45 pm-9:20 pm

2 stops10h 35m

San Francisco

Wed 4/22

7:40 pm-9:55 am

2 stops11h 15m

$351

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Mon 5/11

7:48 pm-8:36 pm

3 stops27h 48m

San Francisco

Mon 5/18

12:18 pm-7:48 pm

Nonstop4h 30m

$357

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 4/30

2:27 pm-5:34 pm

2 stops30h 07m

San Francisco

Fri 5/8

12:18 pm-7:48 pm

Nonstop4h 30m

$366
Quickest round-trip

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Mon 5/18

9:31 am-11:33 am

Nonstop5h 02m

San Francisco

Mon 5/25

12:18 pm-7:48 pm

Nonstop4h 30m

$367

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Wed 4/22

5:00 am-9:16 am

1 stop7h 16m

San Francisco

Tue 5/5

5:00 am-2:41 pm

1 stop6h 41m

$370

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Fri 5/1

6:06 pm-5:34 pm

2 stops26h 28m

San Francisco

Tue 5/5

8:48 pm-7:26 pm

1 stop19h 38m

$372

LouisvilleSan Francisco

SDF - SFO

SDFSFO

Louisville Intl

Thu 4/30

6:00 pm-8:09 pm

Nonstop5h 09m

San Francisco

Sat 5/2

10:35 pm-6:16 am

Nonstop4h 41m

$373

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Louisville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of September, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $287.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Louisville to San Francisco is on a Wednesday when prices can be found for as low as $258. The most expensive day to fly to San Francisco is Thursday, with ticket prices averaging around $312.

What is the cheapest Louisville Intl to San Francisco flight route?

Fly from Louisville Intl to San Francisco for the best Louisville Intl - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $379 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Louisville for as low as $246 on momondo.

What cabin class options are available on Louisville Intl to San Francisco flights?

There is only 1 cabin class available to choose from on Louisville Intl to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Louisville to San Francisco flights?

You could potentially save up to 8% on your flight if you consider stops on a Louisville to San Francisco flight.

How have Louisville to San Francisco flight prices changed over time?

As of March 2026, prices for Louisville to San Francisco flights are approximately 61% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to San Francisco (SDF to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to San Francisco

Best Price Found

$209

Fastest flight time

5h 02m

Direct flights

Tue and Sat

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Louisville in the past 72 hours is $209. The best round-trip flight deal from Louisville to San Francisco found on momondo in the last 72 hours is $248.
The fastest flight from Louisville to San Francisco takes 5h 02m
Direct flights go from Louisville to San Francisco on Tuesday and Saturday. The only airline offering direct flights is Breeze Airways.
There is 1 airport in San Francisco. From Louisville there are direct flights to San Francisco (SFO).
Search flight deals

  • How far is Louisville Intl to San Francisco by plane?

    The distance between Louisville Intl and San Francisco is about 1981.0 mi. By plane, this route typically takes 5h 02m.

  • When did momondo last update prices for flights from Louisville Intl Airport to San Francisco Airport?

    Prices for flights from Louisville Intl Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Louisville Intl Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Louisville to San Francisco?

  • What is the most popular airline from Louisville to San Francisco?

Best airlines flying from Louisville to San Francisco

Compare and see reviews for airlines that fly from Louisville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $139Free CancellationRating
8.1
273 reviews
Search Breeze Airways flights
DeltaPriceFrom $142Free CancellationRating
7.9
8,319 reviews
Search Delta flights
SouthwestPriceFrom $254Free CancellationRating
8.0
4,324 reviews
Search Southwest flights
American AirlinesPriceFrom $262Free CancellationRating
7.1
11,488 reviews
Search American Airlines flights
United AirlinesPriceFrom $283Free CancellationRating
7.4
9,462 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Half Moon Bay
Daly City
Milpitas
Pacific Grove
South San Francisco

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Louisville.

Can I find flights from Louisville to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to San Francisco?

momondo helps you find the best flight between Louisville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Louisville to San Francisco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisville to San Francisco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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