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Cheap flights from Knoxville to Portland from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Portland departing on 2/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Portland

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:02 pm - 11:50 pm
TYS
-
PWM
6h 48m
1 stop
American Airlines Logo
5:42 am - 10:58 am
PWM
-
TYS
5h 16m
1 stop
$289American Airlines
Wed, Feb 18 - Sun, Feb 22
Southwest Logo
8:05 am - 2:10 pm
TYS
-
PWM
6h 05m
1 stop
Southwest Logo
5:40 am - 6:30 pm
PWM
-
TYS
12h 50m
2 stops
$290Southwest
Thu, Apr 16 - Sat, Apr 25
Southwest Logo
8:05 am - 2:10 pm
TYS
-
PWM
6h 05m
1 stop
Southwest Logo
5:40 am - 1:20 pm
PWM
-
TYS
7h 40m
1 stop
$305Southwest
Thu, Apr 16 - Sat, Apr 25
Delta Logo
5:26 pm - 11:22 pm
TYS
-
PWM
5h 56m
1 stop
Delta Logo
5:30 am - 11:08 am
PWM
-
TYS
5h 38m
1 stop
$329Delta
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
3:00 pm - 11:43 pm
TYS
-
PWM
8h 43m
2 stops
American Airlines Logo
5:20 am - 11:03 am
PWM
-
TYS
5h 43m
1 stop
$334American Airlines
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
4:00 pm - 11:43 pm
TYS
-
PWM
7h 43m
2 stops
American Airlines Logo
5:20 am - 1:54 pm
PWM
-
TYS
8h 34m
2 stops
$340American Airlines
Wed, Feb 4 - Sun, Feb 8
United Airlines Logo
9:40 am - 2:23 pm
TYS
-
PWM
4h 43m
1 stop
United Airlines Logo
6:00 am - 4:52 pm
PWM
-
TYS
10h 52m
2 stops
$393United Airlines
Wed, Feb 18 - Sun, Feb 22
United Airlines Logo
6:45 am - 2:23 pm
TYS
-
PWM
7h 38m
2 stops
United Airlines Logo
6:00 am - 4:52 pm
PWM
-
TYS
10h 52m
2 stops
$398United Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
3:00 pm - 10:07 pm
TYS
-
PWM
7h 07m
1 stop
American Airlines Logo
5:20 am - 10:49 am
PWM
-
TYS
5h 29m
1 stop
$439American Airlines
Sat, Jan 24 - Mon, Jan 26
American Airlines Logo
4:06 pm - 10:07 pm
TYS
-
PWM
6h 01m
1 stop
American Airlines Logo
12:46 pm - 10:54 pm
PWM
-
TYS
10h 08m
2 stops
$444American Airlines
Sat, Jan 24 - Mon, Jan 26

American Airlines flights from Knoxville to Portland, Maine

Our best American Airlines deals on Knoxville to Portland, Maine flight tickets
American Airlines
Feb 28
TYS6:05 amKnoxville McGhee Tyson
4h 35m
1 stop
PWM10:40 amPortland
Mar 3
PWM5:07 pmPortland
4h 41m
1 stop
TYS9:48 pmKnoxville McGhee Tyson
$279
American Airlines
Feb 28
TYS6:05 amKnoxville McGhee Tyson
4h 35m
1 stop
PWM10:40 amPortland
Mar 3
PWM7:00 amPortland
9h 31m
2 stops
TYS4:31 pmKnoxville McGhee Tyson
$284
American Airlines
Feb 18
TYS5:02 pmKnoxville McGhee Tyson
6h 48m
1 stop
PWM11:50 pmPortland
Feb 22
PWM5:42 amPortland
5h 16m
1 stop
TYS10:58 amKnoxville McGhee Tyson
$289

Southwest flights from Knoxville to Portland, Maine

Our best Southwest deals on Knoxville to Portland, Maine flight tickets
Southwest
Apr 16
TYS8:05 amKnoxville McGhee Tyson
6h 05m
1 stop
PWM2:10 pmPortland
Apr 25
PWM5:40 amPortland
12h 50m
2 stops
TYS6:30 pmKnoxville McGhee Tyson
$290
Southwest
Apr 16
TYS8:05 amKnoxville McGhee Tyson
6h 05m
1 stop
PWM2:10 pmPortland
Apr 25
PWM5:40 amPortland
7h 40m
1 stop
TYS1:20 pmKnoxville McGhee Tyson
$305
Southwest
Jun 25
TYS6:40 amKnoxville McGhee Tyson
7h 50m
1 stop
PWM2:30 pmPortland
Jul 1
PWM5:30 amPortland
11h 30m
2 stops
TYS5:00 pmKnoxville McGhee Tyson
$310

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Portland, Maine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Knoxville to Portland, Maine that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 2/18

5:02 pm-11:50 pm

1 stop6h 48m

Portland

Sun 2/22

5:42 am-10:58 am

1 stop5h 16m

$289

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Thu 4/16

8:05 am-2:10 pm

1 stop6h 05m

Portland

Sat 4/25

5:40 am-6:30 pm

2 stops12h 50m

$290

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Thu 4/16

8:05 am-2:10 pm

1 stop6h 05m

Portland

Sat 4/25

5:40 am-1:20 pm

1 stop7h 40m

$305

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 2/4

5:26 pm-11:22 pm

1 stop5h 56m

Portland

Sun 2/8

5:30 am-11:08 am

1 stop5h 38m

$329

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 2/4

3:00 pm-11:43 pm

2 stops8h 43m

Portland

Sun 2/8

5:20 am-11:03 am

1 stop5h 43m

$334

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 2/4

4:00 pm-11:43 pm

2 stops7h 43m

Portland

Sun 2/8

5:20 am-1:54 pm

2 stops8h 34m

$340

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 2/18

9:40 am-2:23 pm

1 stop4h 43m

Portland

Sun 2/22

6:00 am-4:52 pm

2 stops10h 52m

$393

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 2/18

6:45 am-2:23 pm

2 stops7h 38m

Portland

Sun 2/22

6:00 am-4:52 pm

2 stops10h 52m

$398

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sat 1/24

3:00 pm-10:07 pm

1 stop7h 07m

Portland

Mon 1/26

5:20 am-10:49 am

1 stop5h 29m

$439

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sat 1/24

4:06 pm-10:07 pm

1 stop6h 01m

Portland

Mon 1/26

12:46 pm-10:54 pm

2 stops10h 08m

$444

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Portland from

How to get the cheapest flight ticket from Knoxville to Portland, Maine

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Portland, Maine?

The cheapest month to fly to Portland, Maine from Knoxville is in September. Flight prices, which tend to average around $298, are often lower during this time because this is during the off-season. If you aren’t able to travel to Portland, Maine during the month of September, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $328.

When to book flights from Knoxville to Portland, Maine

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Portland, Maine according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Portland, Maine (TYS to PWM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Portland, Maine

Fastest flight time

4h 05m

Direct flights

None
The fastest flight from Knoxville to Portland, Maine takes 4h 05m
There are no direct flights from Knoxville to Portland, Maine. There are no popular flight routes from Knoxville to Portland, Maine.
Search flight deals

  • How far is Knoxville McGhee Tyson to Portland by plane?

    A flight from Knoxville McGhee Tyson to Portland will travel around 897.0 mi. Flights usually cover this in 4h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Portland Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Portland Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Portland Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Portland Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Portland Airport.

  • What documentation or ID do you need to fly to Portland Airport?

    The travel and health documents required for your trip to Portland Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Portland Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Knoxville to Portland, Maine?

Best airlines flying from Knoxville to Portland, Maine

Compare and see reviews for airlines that fly from Knoxville to Portland, Maine with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
7.9
8,088 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,174 reviews
Search American Airlines flights
United AirlinesPriceFrom $340Free CancellationRating
7.4
9,191 reviews
Search United Airlines flights

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Boothbay Harbor
Jackson
Conway
Freeport
Lewiston
Brunswick
Bartlett
Gorham
Auburn
Windham
Intervale
Oxford
Bath
Georgetown
Falmouth
Tamworth

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Portland?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Portland from Knoxville.

Can I find flights from Knoxville to Portland with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Portland from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Portland?

Once all potential Knoxville to Portland flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Portland right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Portland now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Portland and let you know when they change.

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Fri 2/20
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