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Cheap flights from Knoxville to Portland from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Portland departing on 2/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Portland

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
7:50 am - 11:55 am
TYS
-
PWM
4h 05m1 stop
Southwest Logo
5:30 am - 6:45 pm
PWM
-
TYS
13h 15m2 stops
$290Southwest
Mon, Mar 16 - Mon, Mar 23
Southwest Logo
8:05 am - 2:10 pm
TYS
-
PWM
6h 05m1 stop
Southwest Logo
5:30 am - 6:10 pm
PWM
-
TYS
12h 40m2 stops
$309Southwest
Fri, May 1 - Mon, May 4
Southwest Logo
7:50 am - 2:15 pm
TYS
-
PWM
6h 25m1 stop
Southwest Logo
2:50 pm - 10:10 pm
PWM
-
TYS
7h 20m1 stop
$318Southwest
Mon, Mar 16 - Mon, Mar 23
United Airlines Logo
9:50 am - 2:40 pm
TYS
-
PWM
4h 50m1 stop
United Airlines Logo
7:30 pm - 11:59 pm
PWM
-
TYS
4h 29m1 stop
$323United Airlines
Thu, Dec 25 - Thu, Jan 1
Southwest Logo
1:20 pm - 12:05 am
TYS
-
PWM
10h 45m2 stops
Southwest Logo
5:30 am - 6:45 pm
PWM
-
TYS
13h 15m2 stops
$334Southwest
Mon, Mar 16 - Mon, Mar 23
Southwest Logo
6:35 am - 4:15 pm
TYS
-
PWM
9h 40m2 stops
Southwest Logo
5:30 am - 6:10 pm
PWM
-
TYS
12h 40m2 stops
$348Southwest
Fri, May 1 - Mon, May 4
Southwest Logo
1:20 pm - 12:05 am
TYS
-
PWM
10h 45m2 stops
Southwest Logo
5:30 am - 6:45 pm
PWM
-
TYS
13h 15m2 stops
$354Southwest
Mon, Mar 16 - Mon, Mar 23
Southwest Logo
7:05 am - 3:05 pm
TYS
-
PWM
8h 00m1 stop
Southwest Logo
5:35 am - 2:05 pm
PWM
-
TYS
8h 30m2 stops
$379Southwest
Sun, Jun 7 - Sat, Jun 13
Southwest Logo
12:45 pm - 12:05 am
TYS
-
PWM
11h 20m2 stops
Southwest Logo
5:35 am - 2:05 pm
PWM
-
TYS
8h 30m2 stops
$399Southwest
Sun, Jun 7 - Sat, Jun 13
Southwest Logo
7:05 am - 3:05 pm
TYS
-
PWM
8h 00m1 stop
Southwest Logo
4:55 pm - 9:20 pm
PWM
-
TYS
4h 25m1 stop
$403Southwest
Sun, Jun 7 - Sat, Jun 13

Southwest flights from Knoxville to Portland, Maine

Our best Southwest deals on Knoxville to Portland, Maine flight tickets
Southwest
Mar 16
TYS7:50 amKnoxville McGhee Tyson
4h 05m
1 stop
PWM11:55 amPortland
Mar 23
PWM5:30 amPortland
13h 15m
2 stops
TYS6:45 pmKnoxville McGhee Tyson
$290
Find similar
Southwest
May 1
TYS8:05 amKnoxville McGhee Tyson
6h 05m
1 stop
PWM2:10 pmPortland
May 4
PWM5:30 amPortland
12h 40m
2 stops
TYS6:10 pmKnoxville McGhee Tyson
$309
Find similar
Southwest
Mar 16
TYS7:50 amKnoxville McGhee Tyson
6h 25m
1 stop
PWM2:15 pmPortland
Mar 23
PWM2:50 pmPortland
7h 20m
1 stop
TYS10:10 pmKnoxville McGhee Tyson
$318
Find similar

United Airlines flights from Knoxville to Portland, Maine

Our best United Airlines deals on Knoxville to Portland, Maine flight tickets
United Airlines
Dec 25
TYS9:50 amKnoxville McGhee Tyson
4h 50m
1 stop
PWM2:40 pmPortland
Jan 1
PWM7:30 pmPortland
4h 29m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
$323
Find similar
United Airlines
Jan 24
TYS2:25 pmKnoxville McGhee Tyson
4h 29m
1 stop
PWM6:54 pmPortland
Jan 28
PWM2:31 pmPortland
4h 56m
1 stop
TYS7:27 pmKnoxville McGhee Tyson
$409
Find similar
United Airlines
Jan 24
TYS6:45 amKnoxville McGhee Tyson
7h 54m
1 stop
PWM2:39 pmPortland
Jan 28
PWM11:12 amPortland
9h 40m
2 stops
TYS8:52 pmKnoxville McGhee Tyson
$414
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Portland, Maine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Knoxville to Portland, Maine that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 3/16

7:50 am-11:55 am

1 stop4h 05m

Portland

Mon 3/23

5:30 am-6:45 pm

2 stops13h 15m

$290

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Fri 5/1

8:05 am-2:10 pm

1 stop6h 05m

Portland

Mon 5/4

5:30 am-6:10 pm

2 stops12h 40m

$309

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 3/16

7:50 am-2:15 pm

1 stop6h 25m

Portland

Mon 3/23

2:50 pm-10:10 pm

1 stop7h 20m

$318

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Thu 12/25

9:50 am-2:40 pm

1 stop4h 50m

Portland

Thu 1/1

7:30 pm-11:59 pm

1 stop4h 29m

$323

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 3/16

1:20 pm-12:05 am

2 stops10h 45m

Portland

Mon 3/23

5:30 am-6:45 pm

2 stops13h 15m

$334

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Fri 5/1

6:35 am-4:15 pm

2 stops9h 40m

Portland

Mon 5/4

5:30 am-6:10 pm

2 stops12h 40m

$348

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 3/16

1:20 pm-12:05 am

2 stops10h 45m

Portland

Mon 3/23

5:30 am-6:45 pm

2 stops13h 15m

$354

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sun 6/7

7:05 am-3:05 pm

1 stop8h 00m

Portland

Sat 6/13

5:35 am-2:05 pm

2 stops8h 30m

$379

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sun 6/7

12:45 pm-12:05 am

2 stops11h 20m

Portland

Sat 6/13

5:35 am-2:05 pm

2 stops8h 30m

$399

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sun 6/7

7:05 am-3:05 pm

1 stop8h 00m

Portland

Sat 6/13

4:55 pm-9:20 pm

1 stop4h 25m

$403

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Portland from

How to get the cheapest flight ticket from Knoxville to Portland, Maine

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Portland, Maine?

The cheapest month to fly to Portland, Maine from Knoxville is in January. Flight prices, which tend to average around $258, are often lower during this time because this is during the off-season. If you aren’t able to travel to Portland, Maine during the month of January, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $278.

What is the cheapest day to depart on your flight to Portland, Maine?

On average, the least expensive day to fly to Portland, Maine from Knoxville is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $331. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $452.

What is the cheapest time of day to depart on your flight to Portland, Maine?

In the afternoon is the cheapest time of day to fly from Knoxville to Portland, Maine when you can find flight prices for as low as $325. Flying to Portland, Maine in the afternoon is an ideal time because this is during off-peak travel hours. Try not to purchase tickets in the evening because they tend to be around $452. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Portland, Maine?

You are more likely to see cheaper flights to Portland, Maine from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Portland, Maine for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Portland, Maine from Knoxville for as low as $274 on momondo.

When to book flights from Knoxville to Portland, Maine

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Portland, Maine according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Portland, Maine (TYS to PWM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Portland, Maine

Fastest flight time

4h 05m

Direct flights

None
The fastest flight from Knoxville to Portland, Maine takes 4h 05m
There are no direct flights from Knoxville to Portland, Maine. There are no popular flight routes from Knoxville to Portland, Maine.
Search flight deals

  • How far is Knoxville McGhee Tyson to Portland by plane?

    A flight from Knoxville McGhee Tyson to Portland will travel around 897.0 mi. Flights usually cover this in 4h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Portland Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Portland Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Portland Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Portland Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Portland Airport.

  • What documentation or ID do you need to fly to Portland Airport?

    The travel and health documents required for your trip to Portland Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Portland Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Knoxville to Portland, Maine?

Best airlines flying from Knoxville to Portland, Maine

Compare and see reviews for airlines that fly from Knoxville to Portland, Maine with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
7.9
8,011 reviews
Search Delta flights
United AirlinesPriceFrom $258Free CancellationRating
7.4
9,089 reviews
Search United Airlines flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Boothbay Harbor
Jackson
Conway
Freeport
Lewiston
Bartlett
Brunswick
Auburn
Gorham
Windham
Intervale
Oxford
Bath
Georgetown
Falmouth
Tamworth

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Portland?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Portland from Knoxville.

Can I find flights from Knoxville to Portland with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Portland from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Portland?

Once all potential Knoxville to Portland flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Portland right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Portland now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Portland and let you know when they change.

An easier way to manage your Portland, Maine trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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