Cheap flights from Guatemala City to San Francisco from $220

If you aren’t able to travel to San Francisco during the month of February, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $342.

The cheapest day to depart from Guatemala City to San Francisco is on a Monday when prices can be found for as low as $353. The most expensive day to fly to San Francisco is Tuesday, with ticket prices averaging around $585.

Fly from Guatemala City La Aurora to San Francisco for the best Guatemala City La Aurora - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Guatemala City when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $416 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Guatemala City for as low as $341 on momondo.

As of May 2026, prices for Guatemala City to San Francisco flights are approximately 66% more expensive when compared to flights at the same time last year.

United Airlines is the most popular carrier operating from Guatemala City La Aurora to San Francisco

Avianca, United Airlines and American Airlines are the top three most popular airlines that fly to San Francisco from Guatemala City according to our data. Avianca is the first choice among our users, with 65% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 4 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 100% of flights between Guatemala City and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 248 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Houston (IAH) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.

Flights via Houston (IAH) offer the lowest average round-trip price of $394.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 9h 16m.

San Salvador (SAL) has the shortest average layover time for this route: 2h 43m.